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prazosin and Elevated Cholesterol

prazosin has been researched along with Elevated Cholesterol in 17 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"The effect of enalapril and terazosin on serum lipid profile was investigated in 36 patients with primary hypertension and hypercholesterolemia (total cholesterol 5."7.68[Effect of enalapril and terazosin on lipid metabolism in patients with essential arterial hypertension and accompanying hypercholesterolemia]. ( Hańczycowa, H; Jordanek, P; Jurga, M; Ponikowski, P; Rotter, A; Sebzda, T; Spring, A, 1993)
"In an open multicenter prospective study, the effects of short-term (4 weeks, n = 101) and long-term (6 months, n = 38) terazosin treatment on blood pressure, serum lipids and safety in the patients with mild to moderate essential hypertension were observed."5.09Effect of terazosin on blood pressure and serum lipids. ( Cheng, L; Gong, P; Lu, Z; Tang, J; Zeng, F; Zhang, J, 1999)
"The effect of enalapril and terazosin on serum lipid profile was investigated in 36 patients with primary hypertension and hypercholesterolemia (total cholesterol 5."3.68[Effect of enalapril and terazosin on lipid metabolism in patients with essential arterial hypertension and accompanying hypercholesterolemia]. ( Hańczycowa, H; Jordanek, P; Jurga, M; Ponikowski, P; Rotter, A; Sebzda, T; Spring, A, 1993)
"Prazosin (Minipress) monotherapy was given to 152 patients with essential hypertension for one year in a multi-center study involving 13 hospitals and university clinics."3.68[The anti-lipidemic effect of Minipress]. ( Dudás, M; Farsang, C; Földes, I; Iványi, J; Pados, G, 1990)
"The effect of doxazosin administration on hemodynamics, hemostasis, and serum lipid and lipoprotein levels was investigated in cynomolgus monkeys (Macaca fascicularis) with diet-induced hypercholesterolemia."3.67Serum lipids, lipoproteins, hemodynamics, and hemostasis in doxazosin-treated monkeys. ( Karge, WH; Kowala, MC; Nicolosi, RJ; Weiner, EJ, 1989)
"Because coronary heart disease is known to have many causes, primary preventive therapy must logically go beyond the relatively simple goal of lowering blood pressure."2.66Effects of oral antihypertensive agents on blood lipid levels. ( Leren, P, 1986)
"Prazosin treatment significantly decreased mean arterial pressure in normal and hypercholesterolemic monkeys."1.28Effects of prazosin on hemodynamics, hemostasis, and serum lipid and lipoprotein levels in normal and hypercholesterolemic monkeys. ( Graham, RM; Karge, WH; Kowala, MC; Nicolosi, RJ; Weiner, EJ, 1989)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19908 (47.06)18.7374
1990's7 (41.18)18.2507
2000's2 (11.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bur, A1
Woisetschläger, C1
Herkner, H1
Derhaschnig, U1
Quehenberger, P1
Hirschl, MM1
Gong, P1
Tang, J1
Cheng, L1
Lu, Z1
Zhang, J1
Zeng, F1
Jatwa, R1
Kar, A1
Ponikowski, P1
Hańczycowa, H1
Sebzda, T1
Jurga, M1
Spring, A1
Rotter, A1
Jordanek, P1
Makaritsis, KP1
Gavras, H1
Du, Y1
Chobanian, AV1
Brecher, P1
Foxall, TL1
Shwaery, GT1
Stucchi, AF1
Nicolosi, RJ3
Wong, SS1
Jansson, JH1
Johansson, B1
Boman, K1
Nilsson, TK1
Pool, JL1
Lenz, ML1
Taylor, AA1
Pados, G1
Iványi, J1
Földes, I1
Dudás, M1
Farsang, C1
Karge, WH2
Kowala, MC2
Weiner, EJ2
Jansen, H1
Lammers, R1
Baggen, MG1
Penders, JM1
Birkenhäger, JC1
Leren, P1
Swindell, AC1
Valentine, JJ1
Seki, K1
Watanabe, T1
Suga, T1
Leren, TP1
Berg, K1
Graham, RM1
Leon, AS1
Hunninghake, DB1
Belcher, J1
Stoulil, J1

Trials

5 trials available for prazosin and Elevated Cholesterol

ArticleYear
[Effects of terazosine and atenolol on serum lipids in essential hypertension].
    Zeitschrift fur Kardiologie, 2002, Volume: 91, Issue:9

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Ate

2002
Effect of terazosin on blood pressure and serum lipids.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1999, Volume: 19, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Essential Hypertension; Humans; Hypercholesterolemia; Hyper

1999
Effects of doxazosin and atenolol on the fibrinolytic system in patients with hypertension and elevated serum cholesterol.
    European journal of clinical pharmacology, 1991, Volume: 40, Issue:4

    Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Body Weight; Double-Blind Method; Doxazosi

1991
Effects of oral antihypertensive agents on blood lipid levels.
    Clinical therapeutics, 1986, Volume: 8, Issue:3

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Cl

1986
Comparative effects of prazosin and propranolol on blood lipid profiles in hypertensive, hypercholesterolemic patients. Preliminary results.
    The American journal of medicine, 1989, Jan-23, Volume: 86, Issue:1B

    Topics: Adult; Aged; Apoproteins; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholester

1989

Other Studies

12 other studies available for prazosin and Elevated Cholesterol

ArticleYear
Cardio-protective role of terazosin is possibly mediated through alteration in thyroid function.
    European journal of pharmacology, 2006, Dec-03, Volume: 551, Issue:1-3

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Cholesterol, Dietary; Disease Models, Animal;

2006
[Effect of enalapril and terazosin on lipid metabolism in patients with essential arterial hypertension and accompanying hypercholesterolemia].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1993, Volume: 46, Issue:7-8

    Topics: Adrenergic alpha-Antagonists; Adult; Enalapril; Female; Humans; Hypercholesterolemia; Hypertension;

1993
Alpha1-adrenergic plus angiotensin receptor blockade reduces atherosclerosis in apolipoprotein E-deficient mice.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:6

    Topics: Adrenergic alpha-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Ap

1998
Dose-related effects of doxazosin on plasma lipids and aortic fatty streak formation in the hypercholesterolemic hamster model.
    The American journal of pathology, 1992, Volume: 140, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Aortic Diseases; Arteriosclerosis; Cricetinae; Dose-Response

1992
Alpha 1-adrenoreceptor blockade and the molecular basis of lipid metabolism alterations.
    Journal of human hypertension, 1990, Volume: 4 Suppl 3

    Topics: Adrenergic alpha-Antagonists; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Dox

1990
[The anti-lipidemic effect of Minipress].
    Orvosi hetilap, 1990, May-27, Volume: 131, Issue:21

    Topics: Coronary Disease; Drug Evaluation; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertension; Hypo

1990
Serum lipids, lipoproteins, hemodynamics, and hemostasis in doxazosin-treated monkeys.
    Journal of cardiovascular pharmacology, 1989, Volume: 13 Suppl 2

    Topics: Adrenergic alpha-Antagonists; Animals; Apolipoproteins B; Disease Models, Animal; Doxazosin; Hemodyn

1989
Inhibition of hepatic cholesterol synthesis by the alpha 1-adrenoceptor blocker doxazosin in the hypercholesterolemic golden hamster.
    Life sciences, 1989, Volume: 44, Issue:15

    Topics: Acetates; Adrenergic alpha-Antagonists; Animals; Cholesterol; Cholesterol, Dietary; Cricetinae; Doxa

1989
Effects of doxazosin on diet-induced hypercholesterolemia in C57BR/cdJ mice.
    The American journal of cardiology, 1987, May-29, Volume: 59, Issue:14

    Topics: Adrenergic alpha-Antagonists; Animals; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Dise

1987
Influence of the new antihypertensive drug, SM-2470 (a quinazoline derivative), on cholesterol metabolism in rats.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:11

    Topics: Adrenergic alpha-Antagonists; Animals; Cholesterol; Hypercholesterolemia; Intestinal Absorption; Int

1987
Studies of serum lipids in hypercholesterolaemic rabbits treated with doxazosin.
    Scandinavian journal of clinical and laboratory investigation, 1988, Volume: 48, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Chinchilla; Cholesterol; Doxazosin; Drug Evaluation, Preclini

1988
Effects of prazosin on hemodynamics, hemostasis, and serum lipid and lipoprotein levels in normal and hypercholesterolemic monkeys.
    The American journal of medicine, 1989, Jan-23, Volume: 86, Issue:1B

    Topics: Animals; Apoproteins; Blood Coagulation; Blood Pressure; Cholesterol; Heart Rate; Hemodynamics; Hemo

1989