prazosin has been researched along with Drop Attack in 10 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a 71-year-old male patient who developed acute myocardial infarction (AMI) due to a dynamic left ventricular outflow tract obstruction induced by terazosin." | 7.83 | Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report. ( Ferrando-Castagnetto, F; Lluberas, N; Martínez, F; Vidal Margenat, A; Vignolo, G, 2016) |
| " In a four-trial, randomized placebo-controlled crossover experiment, 12 normotensive volunteers (aged 25 ± 1 yrs; mean ± SE) completed a 60° head-upward tilt (HUT; 15 min or until onset of presyncope) at 06:00 and 16:00 h, 90 min after the administration of either α(1)-blockade (prazosin, 1 mg/20 kg body weight) or placebo." | 5.16 | The effect of time-of-day and sympathetic α1-blockade on orthostatic tolerance. ( Ainslie, PN; Atkinson, G; Grant, EJ; Jones, H; Lewis, NC; Lucas, SJ, 2012) |
| "We describe a 71-year-old male patient who developed acute myocardial infarction (AMI) due to a dynamic left ventricular outflow tract obstruction induced by terazosin." | 3.83 | Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report. ( Ferrando-Castagnetto, F; Lluberas, N; Martínez, F; Vidal Margenat, A; Vignolo, G, 2016) |
| "Treatment of benign prostatic hyperplasia (BPH) with nonselective alpha1 antagonists such as terazosin, doxazosin, and prazosin results in blood pressure reduction due to vasodilation." | 3.71 | Initiation of nonselective alpha1-antagonist therapy and occurrence of hypotension-related adverse events among men with benign prostatic hyperplasia: a retrospective cohort study. ( Chao, J; Chrischilles, E; Gilden, D; Kreder, KJ; Rubenstein, L; Shah, H, 2001) |
| "The safety of terazosin, an effective agent for the treatment of hypertension, was assessed by analyzing data from 1,006 hypertensive patients who were enrolled in short-term and/or long-term studies." | 3.67 | Overall safety of terazosin as an antihypertensive agent. ( Glassman, HN; Jordan, DC; Luther, RR; Sperzel, WD, 1986) |
| "Hence, paragangliomas are occasionally misdiagnosed, and this results in unanticipated intraoperative hypertensive crisis." | 1.56 | Micturition syncope secondary to urinary bladder paraganglioma. ( Cherian, KE; Johnson, JT; Kapoor, N; Paul, TV, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohyama, K | 1 |
| Hori, Y | 1 |
| Sugiura, M | 1 |
| Johnson, JT | 1 |
| Cherian, KE | 1 |
| Kapoor, N | 1 |
| Paul, TV | 1 |
| Vidal Margenat, A | 1 |
| Ferrando-Castagnetto, F | 1 |
| Martínez, F | 1 |
| Lluberas, N | 1 |
| Vignolo, G | 1 |
| Lewis, NC | 2 |
| Ainslie, PN | 2 |
| Atkinson, G | 2 |
| Jones, H | 2 |
| Grant, EJ | 2 |
| Lucas, SJ | 2 |
| Seideman, P | 1 |
| Grahnén, A | 1 |
| Haglund, K | 1 |
| Lindström, B | 1 |
| von Bahr, C | 1 |
| Rubin, P | 1 |
| Jackson, G | 1 |
| Blaschke, T | 1 |
| Ball, J | 1 |
| Chrischilles, E | 1 |
| Rubenstein, L | 1 |
| Chao, J | 1 |
| Kreder, KJ | 1 |
| Gilden, D | 1 |
| Shah, H | 1 |
| Sperzel, WD | 1 |
| Glassman, HN | 1 |
| Jordan, DC | 1 |
| Luther, RR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Systemic Alfuzosin and Tamsulosin Hydrochloride on Choroidal Thickness and Pupil Diameter Sizes in Cases With Benign Prostatic Hyperplasia[NCT03144596] | Phase 4 | 63 participants (Actual) | Interventional | 2015-10-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for prazosin and Drop Attack
| Article | Year |
|---|---|
The effect of time-of-day and sympathetic α1-blockade on orthostatic tolerance.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Blood Pressure; Circadian Rhythm; Cross-Over Studies | 2012 |
Initial orthostatic hypotension and cerebral blood flow regulation: effect of α1-adrenoreceptor activity.
Topics: Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adult; Arterial Pressure; Blood Flow | 2013 |
8 other studies available for prazosin and Drop Attack
| Article | Year |
|---|---|
Evaluation of syncope association with α
Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Doxazosin; Humans; Hypertension; Indoles; Male; Midd | 2019 |
Micturition syncope secondary to urinary bladder paraganglioma.
Topics: 3-Iodobenzylguanidine; Adrenergic alpha-1 Receptor Antagonists; Adult; Diagnosis, Differential; Diag | 2020 |
Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Angina Pectoris; Cardiomyopathies; Coronary Angiograp | 2016 |
Prazosin dynamics in hypertension: relationship to plasma concentration.
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle | 1981 |
Studies on the clinical pharmacology of prazosin. II: The influence of indomethacin and of propranolol on the action and disposition of prazosin.
Topics: Adult; Blood Pressure; Drug Interactions; Endocrine Glands; Heart Rate; Humans; Indomethacin; Kineti | 1980 |
Symptomatic sinus bradycardia due to prazosin.
Topics: Bradycardia; Humans; Male; Middle Aged; Prazosin; Syncope | 1994 |
Initiation of nonselective alpha1-antagonist therapy and occurrence of hypotension-related adverse events among men with benign prostatic hyperplasia: a retrospective cohort study.
Topics: Accidental Falls; Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Cohort Studies; Comor | 2001 |
Overall safety of terazosin as an antihypertensive agent.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Asthenia; Body Weight; Dizziness; Female; Hea | 1986 |