Page last updated: 2024-11-03

prazosin and Drop Attack

prazosin has been researched along with Drop Attack in 10 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"We describe a 71-year-old male patient who developed acute myocardial infarction (AMI) due to a dynamic left ventricular outflow tract obstruction induced by terazosin."7.83Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report. ( Ferrando-Castagnetto, F; Lluberas, N; Martínez, F; Vidal Margenat, A; Vignolo, G, 2016)
" In a four-trial, randomized placebo-controlled crossover experiment, 12 normotensive volunteers (aged 25 ± 1 yrs; mean ± SE) completed a 60° head-upward tilt (HUT; 15 min or until onset of presyncope) at 06:00 and 16:00 h, 90 min after the administration of either α(1)-blockade (prazosin, 1 mg/20 kg body weight) or placebo."5.16The effect of time-of-day and sympathetic α1-blockade on orthostatic tolerance. ( Ainslie, PN; Atkinson, G; Grant, EJ; Jones, H; Lewis, NC; Lucas, SJ, 2012)
"We describe a 71-year-old male patient who developed acute myocardial infarction (AMI) due to a dynamic left ventricular outflow tract obstruction induced by terazosin."3.83Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report. ( Ferrando-Castagnetto, F; Lluberas, N; Martínez, F; Vidal Margenat, A; Vignolo, G, 2016)
"Treatment of benign prostatic hyperplasia (BPH) with nonselective alpha1 antagonists such as terazosin, doxazosin, and prazosin results in blood pressure reduction due to vasodilation."3.71Initiation of nonselective alpha1-antagonist therapy and occurrence of hypotension-related adverse events among men with benign prostatic hyperplasia: a retrospective cohort study. ( Chao, J; Chrischilles, E; Gilden, D; Kreder, KJ; Rubenstein, L; Shah, H, 2001)
"The safety of terazosin, an effective agent for the treatment of hypertension, was assessed by analyzing data from 1,006 hypertensive patients who were enrolled in short-term and/or long-term studies."3.67Overall safety of terazosin as an antihypertensive agent. ( Glassman, HN; Jordan, DC; Luther, RR; Sperzel, WD, 1986)
"Hence, paragangliomas are occasionally misdiagnosed, and this results in unanticipated intraoperative hypertensive crisis."1.56Micturition syncope secondary to urinary bladder paraganglioma. ( Cherian, KE; Johnson, JT; Kapoor, N; Paul, TV, 2020)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Ohyama, K1
Hori, Y1
Sugiura, M1
Johnson, JT1
Cherian, KE1
Kapoor, N1
Paul, TV1
Vidal Margenat, A1
Ferrando-Castagnetto, F1
Martínez, F1
Lluberas, N1
Vignolo, G1
Lewis, NC2
Ainslie, PN2
Atkinson, G2
Jones, H2
Grant, EJ2
Lucas, SJ2
Seideman, P1
Grahnén, A1
Haglund, K1
Lindström, B1
von Bahr, C1
Rubin, P1
Jackson, G1
Blaschke, T1
Ball, J1
Chrischilles, E1
Rubenstein, L1
Chao, J1
Kreder, KJ1
Gilden, D1
Shah, H1
Sperzel, WD1
Glassman, HN1
Jordan, DC1
Luther, RR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Systemic Alfuzosin and Tamsulosin Hydrochloride on Choroidal Thickness and Pupil Diameter Sizes in Cases With Benign Prostatic Hyperplasia[NCT03144596]Phase 463 participants (Actual)Interventional2015-10-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for prazosin and Drop Attack

ArticleYear
The effect of time-of-day and sympathetic α1-blockade on orthostatic tolerance.
    Chronobiology international, 2012, Volume: 29, Issue:7

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Blood Pressure; Circadian Rhythm; Cross-Over Studies

2012
Initial orthostatic hypotension and cerebral blood flow regulation: effect of α1-adrenoreceptor activity.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Jan-15, Volume: 304, Issue:2

    Topics: Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adult; Arterial Pressure; Blood Flow

2013

Other Studies

8 other studies available for prazosin and Drop Attack

ArticleYear
Evaluation of syncope association with α
    Die Pharmazie, 2019, 12-01, Volume: 74, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Doxazosin; Humans; Hypertension; Indoles; Male; Midd

2019
Micturition syncope secondary to urinary bladder paraganglioma.
    BMJ case reports, 2020, Mar-12, Volume: 13, Issue:3

    Topics: 3-Iodobenzylguanidine; Adrenergic alpha-1 Receptor Antagonists; Adult; Diagnosis, Differential; Diag

2020
Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report.
    Medwave, 2016, Jun-28, Volume: 16, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Angina Pectoris; Cardiomyopathies; Coronary Angiograp

2016
Prazosin dynamics in hypertension: relationship to plasma concentration.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:4

    Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle

1981
Studies on the clinical pharmacology of prazosin. II: The influence of indomethacin and of propranolol on the action and disposition of prazosin.
    British journal of clinical pharmacology, 1980, Volume: 10, Issue:1

    Topics: Adult; Blood Pressure; Drug Interactions; Endocrine Glands; Heart Rate; Humans; Indomethacin; Kineti

1980
Symptomatic sinus bradycardia due to prazosin.
    Lancet (London, England), 1994, Jan-08, Volume: 343, Issue:8889

    Topics: Bradycardia; Humans; Male; Middle Aged; Prazosin; Syncope

1994
Initiation of nonselective alpha1-antagonist therapy and occurrence of hypotension-related adverse events among men with benign prostatic hyperplasia: a retrospective cohort study.
    Clinical therapeutics, 2001, Volume: 23, Issue:5

    Topics: Accidental Falls; Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Cohort Studies; Comor

2001
Overall safety of terazosin as an antihypertensive agent.
    The American journal of medicine, 1986, May-23, Volume: 80, Issue:5B

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Asthenia; Body Weight; Dizziness; Female; Hea

1986