prazosin has been researched along with Diabetic Neuropathies in 4 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate whether alpha1-adrenoceptors are involved in pain behaviors in streptozotocin (STZ)-induced diabetic rats, we measured the effects of phenylephrine or prazosin on allodynia in the diabetic rats." | 3.70 | Alpha1-adrenoceptors involvement in painful diabetic neuropathy: a role in allodynia. ( Hur, GM; Jeon, BH; Kim, KJ; Lee, YH; Park, SJ; Ryu, TG; Yang, EJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, YH | 1 |
| Ryu, TG | 1 |
| Park, SJ | 1 |
| Yang, EJ | 1 |
| Jeon, BH | 1 |
| Hur, GM | 1 |
| Kim, KJ | 1 |
| Gallego, M | 1 |
| Casis, E | 1 |
| Izquierdo, MJ | 1 |
| Casis, O | 1 |
| Cameron, NE | 1 |
| Cotter, MA | 1 |
| Ferguson, K | 1 |
| Robertson, S | 1 |
| Radcliffe, MA | 1 |
| Moss, HE | 1 |
| Crowe, R | 1 |
| Burnstock, G | 1 |
4 other studies available for prazosin and Diabetic Neuropathies
| Article | Year |
|---|---|
Alpha1-adrenoceptors involvement in painful diabetic neuropathy: a role in allodynia.
Topics: Adrenergic alpha-Antagonists; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Gangl | 2000 |
Restoration of cardiac transient outward potassium current by norepinephrine in diabetic rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Nervous System Disease | 2000 |
Effects of chronic alpha-adrenergic receptor blockade on peripheral nerve conduction, hypoxic resistance, polyols, Na(+)-K(+)-ATPase activity, and vascular supply in STZ-D rats.
Topics: Action Potentials; Alcohols; Animals; Capillaries; Cell Hypoxia; Diabetes Mellitus, Experimental; Di | 1991 |
The seminal vesicle in eight and 16 week streptozotocin-induced diabetic rats: adrenergic, cholinergic and peptidergic innervation.
Topics: Acetylcholine; Adrenergic Fibers; Animals; Cholinergic Fibers; Diabetes Mellitus, Experimental; Diab | 1987 |