prazosin has been researched along with Decerebrate Posturing in 58 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the effects of aging on the blood pressure potency of phenylephrine, 6-, 10- and 40-week-old rats were used." | 3.69 | Age-related changes in alpha-adrenoceptor-mediated blood pressure in the rat: relationship between the potency for phenylephrine and the maximum number of binding sites. ( Kanai, S; Koike, K; Ohtsuki, H; Satoh, M; Takayanagi, I, 1996) |
| " The effect of artificial hypothyroidism (induced by feeding 6-propyl-2-thiouracil, PTU) and hyperthyroidism (induced by daily injections of triiodothyronine, T3) on myocardial adrenoceptor binding, catecholamines, some physiological responses, and their interdependence was examined." | 3.67 | Thyroid-dependent alterations of myocardial adrenoceptors and adrenoceptor-mediated responses in the rat. ( Gross, G; Lues, I, 1985) |
| "Pretreatment with prazosin inhibited (S)-8-OH-DPAT-induced monosynaptic reflex enhancement in intact rats, as did noradrenaline and 5-HT depletion." | 1.30 | Differential effects of (R)- and (S)-8-hydroxy-2-(di-n-propylamino)tetralin on the monosynaptic spinal reflex in rats. ( Honda, M; Ono, H, 1999) |
| " The effects of drugs on IGP, IDP, and ICP (increase or decrease) can be assessed and a dose-response curve before and after antagonists can be computed." | 1.29 | A method for simultaneous measurement of intragastric, intraduodenal, and intracolonic pressures in the bilaterally vagotomized spinal rat. ( Dhasmana, KM; Erdmann, W; Zhu, YN, 1994) |
| "5." | 1.29 | Alfuzosin, a selective alpha 1-adrenoceptor antagonist in the lower urinary tract. ( Gautier, E; Hicks, PE; Langer, SZ; Lechaire, J; Lefèvre-Borg, F; Manoury, P; O'Connor, SE; Pierre, F; Pimoule, C; Schoemaker, H, 1993) |
| " doses of efaroxan (mumol/kg) producing 2-fold shifts in dose-response curves for UK-14,304 at prejunctional cardiac alpha 2-adrenoceptors and postjunctional vascular alpha 2-adrenoceptors, and for cirazoline at postjunctional vascular alpha 1-adrenoceptors, were 0." | 1.28 | Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat. ( Berridge, TL; Doxey, JC; Roach, AG; Smith, CF, 1992) |
| "Prazosin's action was almost totally abolished by monoamine depletion with reserpine and a synthesis inhibitor." | 1.28 | Effect of prazosin on spontaneous sympathetic-cholinergic activity. ( Hey, JA; Ito, T; Koss, MC, 1990) |
| "In pithed rats two recently-introduced beta-blockers, nipradilol and arotinolol, as well as labetalol shifted the pressor dose-response curve for phenylephrine to the right." | 1.27 | Alpha-blockade and vasodilatation induced by nipradilol, arotinolol and labetalol in pithed rats. ( Chin, WP; Imai, S; Nakagawa, Y; Nakahara, H, 1985) |
| " In addition, L-654,284 had better (5-6 times) oral bioavailability than RX 781094 or WY 26703." | 1.27 | L-654,284 a new potent and selective alpha 2-adrenoceptor antagonist. ( Baldwin, JJ; Clineschmidt, BV; Huff, JR; Lotti, VJ; Martin, GE; Pettibone, DJ; Randall, WC; Vacca, J, 1986) |
| " Reserpinization shifted the (-)-norephedrine dose-response curve slightly to the right, indicating that only a minor portion of its activity is due to the release of stored endogenous catecholamines." | 1.27 | Adrenergic receptor subtype activation by (+)-, (-)- and (+/-)-norephedrine in the pithed rat. ( Maher, TJ; Moya-Huff, FA, 1987) |
| " Labetalol and prazosin also significantly shifted the dose-response curve to the right for phenylephrine but not for angiotensin II." | 1.27 | Analysis of the mechanism underlying the vasodilator action of carvedilol in pithed spontaneously hypertensive rats. ( Akashi, A; Hashimoto, H; Kanda, A; Tanaka, M, 1988) |
| "Urapidil is a novel antihypertensive agent, chemically related to uracil." | 1.27 | Cardiovascular effects and interaction with adrenoceptors of urapidil. ( Beckeringh, JJ; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B, 1985) |
| " The dose-response curve to guanfacine for increase in blood pressure was shifted in a parallel fashion to the right by 1 mg/kg of yohimbine, an alpha 2-antagonist and by 1 mg/kg of phentolamine, a nonselective alpha 1- and alpha 2-antagonist." | 1.26 | [Effects of guanfacine on pre- and postsynaptic alpha-adrenoceptors studied in comparison with those of clonidine]. ( Chin, W; Imai, S; Nakagawa, Y, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (56.90) | 18.7374 |
| 1990's | 22 (37.93) | 18.2507 |
| 2000's | 3 (5.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Turner, S | 1 |
| Myers, M | 1 |
| Gadie, B | 1 |
| Nelson, AJ | 1 |
| Pape, R | 1 |
| Saville, JF | 1 |
| Doxey, JC | 2 |
| Berridge, TL | 2 |
| Centurión, D | 1 |
| Mehotra, S | 1 |
| Sánchez-López, A | 1 |
| Gupta, S | 1 |
| MaassenVanDenBrink, A | 1 |
| Villalón, CM | 1 |
| Ruffolo, RR | 5 |
| Morgan, EL | 2 |
| Messick, K | 3 |
| Nakagawa, Y | 2 |
| Chin, W | 1 |
| Imai, S | 2 |
| Timmermans, PB | 5 |
| Matthews, WD | 1 |
| Demarinis, RM | 1 |
| Hieble, JP | 3 |
| Mathy, MJ | 1 |
| Doods, HN | 1 |
| Thoolen, MJ | 5 |
| De Jonge, A | 4 |
| Wilffert, B | 4 |
| Van Zwieten, PA | 6 |
| Goldberg, MR | 1 |
| Tabrizchi, R | 2 |
| Lupichuk, SM | 1 |
| Sugimoto, T | 1 |
| Hosoki, K | 1 |
| Karasawa, T | 1 |
| Takahashi, T | 2 |
| Ono, H | 3 |
| Fukushima, C | 1 |
| Fukuda, H | 1 |
| Cirelli, C | 1 |
| D'Ascanio, P | 1 |
| Horn, E | 1 |
| Pompeiano, O | 1 |
| Stampacchia, G | 1 |
| Zhu, YN | 1 |
| Dhasmana, KM | 1 |
| Erdmann, W | 1 |
| Angel, I | 1 |
| Grosset, A | 1 |
| Perrault, G | 1 |
| Schoemaker, H | 2 |
| Langer, SZ | 2 |
| Lefèvre-Borg, F | 1 |
| O'Connor, SE | 1 |
| Hicks, PE | 1 |
| Lechaire, J | 1 |
| Gautier, E | 1 |
| Pierre, F | 1 |
| Pimoule, C | 1 |
| Manoury, P | 1 |
| Castillo, C | 1 |
| Bobadilla, RA | 1 |
| Ibarra, M | 1 |
| Castillo, EF | 1 |
| Hong, E | 1 |
| Li, Q | 1 |
| Zhang, J | 1 |
| Pfaffendorf, M | 1 |
| Koike, K | 1 |
| Satoh, M | 2 |
| Kanai, S | 1 |
| Ohtsuki, H | 1 |
| Takayanagi, I | 1 |
| Alvarez-Guerra, M | 1 |
| Bertholom, N | 1 |
| Garay, RP | 1 |
| Honda, M | 1 |
| McCafferty, GP | 1 |
| Naselsky, DP | 1 |
| Clarke, RW | 2 |
| Harris, J | 2 |
| Houghton, AK | 1 |
| Elayan, HH | 1 |
| Kennedy, BP | 1 |
| Ziegler, MG | 1 |
| Roach, AG | 1 |
| Smith, CF | 1 |
| Nishizawa, O | 1 |
| Sugaya, K | 1 |
| Shimoda, N | 1 |
| Satoh, K | 1 |
| Otomo, R | 1 |
| Noto, H | 1 |
| Harada, T | 1 |
| Tsuchida, S | 1 |
| Hasebe, Y | 1 |
| Nagao, T | 1 |
| Ohta, S | 1 |
| Hirobe, M | 1 |
| Fuduka, H | 1 |
| Xiao, XH | 1 |
| Rand, MJ | 3 |
| Koss, MC | 1 |
| Hey, JA | 1 |
| Ito, T | 1 |
| Mizutani, M | 1 |
| Neya, T | 1 |
| Nakayama, S | 1 |
| Nakahara, H | 1 |
| Chin, WP | 1 |
| Nichols, AJ | 1 |
| Hamada, A | 1 |
| Adejare, A | 1 |
| Miller, DD | 1 |
| Patil, PN | 1 |
| Lonart, G | 1 |
| Harsing, LG | 1 |
| Folly, G | 1 |
| Vizi, ES | 1 |
| Willette, RN | 1 |
| Sauermelch, C | 1 |
| Tsujimoto, G | 1 |
| Hashimoto, K | 1 |
| De Luca, A | 1 |
| Savola, JM | 1 |
| Puurunen, J | 1 |
| Ruskoaho, H | 1 |
| Kärki, NT | 1 |
| Docherty, JR | 2 |
| Hyland, L | 2 |
| Aono, J | 1 |
| Nabata, H | 1 |
| Ishizuka, N | 1 |
| Sakai, K | 1 |
| van den Berg, G | 1 |
| Qian, JQ | 1 |
| Jie, K | 1 |
| van Brummelen, P | 1 |
| Jonkman, FA | 1 |
| Pettibone, DJ | 1 |
| Clineschmidt, BV | 1 |
| Lotti, VJ | 1 |
| Martin, GE | 1 |
| Huff, JR | 1 |
| Randall, WC | 1 |
| Vacca, J | 1 |
| Baldwin, JJ | 1 |
| Tung, LH | 1 |
| Louis, WJ | 1 |
| Hanazuka, M | 1 |
| Horii, D | 1 |
| Mizogami, S | 1 |
| Moya-Huff, FA | 1 |
| Maher, TJ | 1 |
| Chen, DF | 1 |
| Bianchetti, M | 1 |
| Wiesendanger, M | 1 |
| Hashimoto, H | 1 |
| Tanaka, M | 1 |
| Kanda, A | 1 |
| Akashi, A | 1 |
| Gradin, K | 1 |
| Pettersson, A | 1 |
| Hedner, T | 1 |
| Persson, B | 1 |
| Rawłów, A | 1 |
| Górka, Z | 1 |
| Bulloch, JM | 1 |
| McGrath, JC | 1 |
| Hyman, AL | 1 |
| Dempesy, CW | 1 |
| Fontana, C | 1 |
| Richardson, DE | 1 |
| Rieck, RW | 1 |
| Kadowitz, PJ | 1 |
| Yajima, T | 1 |
| Urano, T | 1 |
| Nakamura, K | 2 |
| Matsuura, A | 1 |
| Himori, N | 1 |
| Gross, G | 1 |
| Lues, I | 1 |
| Beckeringh, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Open-Labeled Study of Prophylactic Vs. Therapeutic Use of Uroxatrol to Determine Improvements in Urinary Morbidity Following Men Undergoing Prostate Brachytherapy[NCT00201630] | Phase 3 | 150 participants | Interventional | 2005-09-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
58 other studies available for prazosin and Decerebrate Posturing
| Article | Year |
|---|---|
Antihypertensive thiadiazoles. 1. Synthesis of some 2-aryl-5-hydrazino-1,3,4-thiadiazoles with vasodilator activity.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Decerebrate State; Hydrazines; Hypertension; Male; | 1988 |
Potential vascular alpha1-adrenoceptor blocking properties of an array of 5-HT receptor ligands in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Rec | 2006 |
Possible relationship between receptor reserve and the differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by calcium channel antagonists in the pithed rat.
Topics: Animals; Aorta, Thoracic; Azepines; Blood Pressure; Decerebrate State; Diltiazem; Dose-Response Rela | 1984 |
[Effects of guanfacine on pre- and postsynaptic alpha-adrenoceptors studied in comparison with those of clonidine].
Topics: Adrenalectomy; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Clonidine; Decerebrate S | 1982 |
Alpha 1-adrenoceptor-mediated vasoconstriction in vivo to enantiomers of SK & F 89748-A.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Blood Pressure; Cats; Clonidine; Decerebra | 1984 |
Interactions of epinephrine, norepinephrine, dopamine and their corresponding alpha-methyl-substituted derivatives with alpha and beta adrenoceptors in the pithed rat.
Topics: Animals; Blood Pressure; Decerebrate State; Deoxyepinephrine; Dopamine; Dose-Response Relationship, | 1984 |
The effects of losartan and captopril on vasopressor actions of cirazoline in the absence and presence of SZL-49 and nifedipine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antihyperten | 1995 |
Relative contribution of alpha 1-adrenoceptor blocking activity to the hypotensive effect of the novel calcium antagonist monatepil.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calc | 1995 |
Influence of nonpeptide angiotensin II receptor antagonist, losartan, on neurogenic vasoconstriction.
Topics: Adenosine Triphosphate; Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Blood Pre | 1995 |
[Alpha adrenergic mechanism on the reflex micturition in the male decerebrate dog].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Decerebrate State; Dogs | 1993 |
Effect of the centrally acting muscle relaxant tizanidine on spinal reflexes: involvement of descending noradrenergic systems.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A | 1993 |
Modulation of vestibulospinal reflexes through microinjection of an alpha 1-adrenergic antagonist in the dorsal pontine tegmentum of decerebrate cats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cats; Decerebrate St | 1993 |
A method for simultaneous measurement of intragastric, intraduodenal, and intracolonic pressures in the bilaterally vagotomized spinal rat.
Topics: Animals; Atropine; Decerebrate State; Dopamine; Female; Gastrointestinal Motility; Male; Prazosin; P | 1994 |
In vivo pharmacological profile of SL 84.0418, a new selective, peripherally active alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Blood Pressure; Bri | 1993 |
Alfuzosin, a selective alpha 1-adrenoceptor antagonist in the lower urinary tract.
Topics: Adenofibroma; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cats; Decerebrate State; | 1993 |
A comparative study of the effects of some 5-HT1A receptor agonists on the blood pressure of pithed rats.
Topics: 5-Methoxytryptamine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; | 1995 |
Direct positive chronotropic effects of angiotensin II and angiotensin III in pithed rats and in rat isolated atria.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin III; Angioten | 1996 |
Age-related changes in alpha-adrenoceptor-mediated blood pressure in the rat: relationship between the potency for phenylephrine and the maximum number of binding sites.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Analysis of Variance; Animals; Aorta | 1996 |
Selective blockade by nicergoline of vascular responses elicited by stimulation of alpha 1A-adrenoceptor subtype in the rat.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An | 1999 |
Differential effects of (R)- and (S)-8-hydroxy-2-(di-n-propylamino)tetralin on the monosynaptic spinal reflex in rats.
Topics: 5,6-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Anima | 1999 |
Characterization of postjunctional alpha-adrenoceptors in the pithed mouse.
Topics: 3T3 Cells; Adrenergic alpha-Antagonists; Animals; Azepines; Binding, Competitive; Blood Pressure; CH | 1999 |
Endogenous adrenergic control of reflexes evoked by mechanical stimulation of the heel in the decerebrated rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Azocines; Blood Pressure; Decerebrate State; Female; Idazoxan | 2001 |
Selective peripheral regulation of noradrenaline and adrenaline release by nitric oxide.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Enzy | 2002 |
Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Benzofurans; Blood Glucose; Brimonidine Tartrate; Clonidine; | 1992 |
An analysis of adrenergic influences on the sural-gastrocnemius reflex of the decerebrated rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Decerebrate State; Dioxanes; Dose-Response Rela | 1992 |
[Effect of terazosin on lower urinary tract function in the male decerebrate dog].
Topics: Animals; Decerebrate State; Dogs; Dose-Response Relationship, Drug; Electromyography; Male; Muscle C | 1992 |
Amphetamine-antagonistic properties of 4-phenyl-1,2,3,4- tetrahydroisoquinoline: inhibition of spinal reflex-enhancing effects of methamphetamine, phenylethylamine and nomifensine.
Topics: Amphetamine; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Isoquinolines; Male; | 1991 |
Effects of the alpha 2-adrenoceptor agonist UK14304 on pressor responses in pithed rats.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Decerebrate State; Dose-Response Relations | 1990 |
Effect of prazosin on spontaneous sympathetic-cholinergic activity.
Topics: Animals; Biogenic Monoamines; Cats; Decerebrate State; Female; Galvanic Skin Response; In Vitro Tech | 1990 |
Capsaicin-sensitive afferents activate a sympathetic intestinointestinal inhibitory reflex in dogs.
Topics: Afferent Pathways; Animals; Capsaicin; Decerebrate State; Dogs; Electric Stimulation; Female; Inject | 1990 |
Alpha-blockade and vasodilatation induced by nipradilol, arotinolol and labetalol in pithed rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Decer | 1985 |
Effect of aromatic fluorine substitution on the alpha and beta adrenoceptor-mediated effects of 3,4-dihydroxytolazoline in the pithed rat.
Topics: Animals; Blood Pressure; Decerebrate State; Fluorine; Heart Rate; Imidazoles; Male; Prazosin; Rats; | 1989 |
Failure of selective antagonists (CH-38083 and idazoxan) to distinguish between prejunctional and postjunctional alpha 2-adrenoreceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Berberine; Berberine Alkaloids; Blood Pressure; Dec | 1989 |
Stimulation of postjunctional alpha-1 and alpha-2 adrenoreceptors increases proximal urethral perfusion pressure in the pithed rat.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Decerebrate State; Perfusion; Phenylephrine; Prazosin; | 1989 |
Effects of triiodo-L-thyronine (T3)-induced hyperthyroidism on the cardiovascular alpha-adrenoceptor system in young and older rats.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Cardiovascular System | 1987 |
Involvement of alpha 1-adrenoceptors in chronotropic responses to endogenously released amines in the pithed rat.
Topics: Animals; Biogenic Amines; Decerebrate State; Diltiazem; Drug Interactions; Electric Stimulation; Hea | 1988 |
Peripheral cardiovascular alpha- and beta-adrenergic effects of some hypotensive and bradycardic arylalkyl imidazole derivatives in the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Clonidi | 1985 |
No evidence for differences between pre- and post-junctional alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Decerebrate State; | 1985 |
Mechanism of the hypotensive effect of a novel phenylpiperazine derivative, SGB-1534: antagonism at alpha 1-adrenergic and 5-HT2 receptors.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Decerebrate State; Gastr | 1985 |
Inhibitory effect of alpha-1 adrenoceptor stimulation on cardiac sympathetic neurotransmission in pithed normotensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Decerebrate State; Ethanolamines; Heart; Heart Rate; | 1986 |
Effects of PN 200-110, a new calcium antagonist, on alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction elicited by selective alpha-adrenoceptor agonists and catecholamines in the pithed rat.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Catecholamin | 1985 |
Central and peripheral effects of S 3341 [(N-dicyclopropylmethyl)-amino-2-oxazoline] in animal models.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cats; Clonidine; De | 1986 |
L-654,284 a new potent and selective alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Cattle; Cerebral Cortex; Clonidine; Decerebrate State; Dihydr | 1986 |
Positive chronotropic responses to cardiac alpha 1-adrenoreceptor activation in the pithed rat.
Topics: Adrenergic alpha-Agonists; Animals; Decerebrate State; Drug Interactions; Epinephrine; Female; Heart | 1986 |
[Alpha-adrenoceptor blocking action of terazosin].
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta; Decerebrate State; Heart Rate | 1986 |
Adrenergic receptor subtype activation by (+)-, (-)- and (+/-)-norephedrine in the pithed rat.
Topics: Animals; Blood Pressure; Cardiovascular System; Decerebrate State; Heart Rate; Isomerism; Male; Phen | 1987 |
The adrenergic agonist tizanidine has differential effects on flexor reflexes of intact and spinalized rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Clonidine; Decerebrate State; Dose-Response | 1987 |
Analysis of the mechanism underlying the vasodilator action of carvedilol in pithed spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Decerebrate State; Dos | 1988 |
Chronic 5-HT2 receptor blockade with ritanserin does not reduce blood pressure in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; | 1985 |
Evaluation of the alpha-1 and alpha-2 adrenoceptor-mediated effects of a series of dimethoxy-substituted tolazoline derivatives in the cardiovascular system of the pithed rat.
Topics: Animals; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dose-Response Relations | 1985 |
Involvement of postsynaptic alpha 1- and alpha 2-adrenoceptors in the flexor reflex activity in the spinal rats.
Topics: Animals; Clonidine; Clozapine; Decerebrate State; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred | 1986 |
Alpha-adrenoceptor responsiveness in the aged rat.
Topics: Aging; Anesthesia; Animals; Blood Pressure; Cocaine; Decerebrate State; Ethanolamines; Heart Rate; M | 1986 |
Selective blockade by nifedipine of 'purinergic' rather than adrenergic nerve-mediated vasopressor responses in the pithed rat.
Topics: Adenosine Triphosphate; Animals; Decerebrate State; Gallamine Triethiodide; Halothane; Nifedipine; P | 1988 |
Pulmonary vascular responses to forebrain stimulation in the cat.
Topics: Animals; Cats; Decerebrate State; Diencephalon; Electric Stimulation; Female; Freezing; Histamine An | 1988 |
Cerebral vasodilating and vasospasmolytic action of the cerebral circulation improver 6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-4-([4-(2-methoxyphenyl)-1- piperazinyl]methyl)isoquinoline in experimental animals.
Topics: Animals; Brain Chemistry; Cats; Cerebrovascular Circulation; Decerebrate State; Dogs; Female; Hypert | 1987 |
Thyroid-dependent alterations of myocardial adrenoceptors and adrenoceptor-mediated responses in the rat.
Topics: Animals; Cycloheximide; Decerebrate State; Dihydroalprenolol; Dose-Response Relationship, Drug; Elec | 1985 |
Cardiovascular effects and interaction with adrenoceptors of urapidil.
Topics: Animals; Antihypertensive Agents; Binding, Competitive; Cats; Clonidine; Decerebrate State; Female; | 1985 |
Inotropic selectivity of dobutamine enantiomers in the pithed rat.
Topics: Animals; Blood Pressure; Decerebrate State; Dobutamine; Dose-Response Relationship, Drug; Heart Rate | 1985 |