Page last updated: 2024-11-03

prazosin and Coronary Disease

prazosin has been researched along with Coronary Disease in 114 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
" This result was not significant but suggested a favorable effect of terazosin on diminishing the risk of coronary heart disease."9.09[Evaluation of serum lipid levels in clinical benign prostatic hyperplasia patients with terazosin monotherapy]. ( Kageyama, S; Tamaki, M; Ueda, T, 1999)
" Forty-two patients, ages 42 to 65 years, including 21 men with sustained hypertension and elevated serum cholesterol levels, were included in a trial of monotherapy with doxazosin administered once daily (range, 1 to 16 mg)."9.07Efficacy and safety of doxazosin in the treatment of patients with mild or moderate essential hypertension and elevated levels of cholesterol. ( Taylor, SH, 1991)
"This Latin American study assessed in the general practice setting the efficacy and tolerance of once-daily doxazosin in the treatment of mild or moderate essential hypertension (sitting diastolic blood pressure, 95 to 115 mm Hg)."9.07Doxazosin in the treatment of essential hypertension in general medical practice in Latin America. ( Fonseca, R; Marshall, D; Silva, H, 1991)
"This study was designed to assess the efficacy and tolerance of doxazosin in patients with mild, moderate, or severe essential hypertension in a general practice setting."9.07A multicenter study of doxazosin in the treatment of essential hypertension in France. ( Bonnet, G, 1991)
"A single daily dose of doxazosin taken during a 12-week period produced a significant reduction in blood pressure and left ventricular mass index in patients with mild or moderate hypertension."9.07Echocardiographic assessment of doxazosin on left ventricular mass in patients with essential hypertension. ( Fonseca, R; López, B; Lugo de Franco, V; Medina, O; Monsalve, P; Ostojich, K; Pérez Acuña, F; Torres, N; Vera, O, 1991)
"Doxazosin is a selective alpha 1-inhibitor for the reduction of calculated coronary heart disease (CHD) risk in hypertensive patients."9.06Doxazosin versus atenolol: a randomized comparison of calculated coronary heart disease risk reduction. ( Guerrasio, E; Mazzola, C, 1988)
"Ten patients with severe chronic heart failure were given prazosin 5 mg and captopril 25 mg in random order on consecutive days."9.05Prazosin and captopril in chronic heart failure: comparison of acute haemodynamic and hormonal effects. ( Coxon, R; Sharpe, DN, 1982)
"Oral prazosin hydrochloride (2-20 mg/day) was administered to 38 patients with chronic congestive heart failure due to ischemic heart disease for 6-18 months."7.68Prazosin in chronic congestive heart failure due to ischemic heart disease. ( Antani, JA; Antani, NJ; Nanivadekar, AS, 1991)
"Although the pathology of essential hypertension is still unclear, studies have shown that doxazosin, a selective alpha 1-inhibitor, is able to effectively control mild-to-moderate hypertension."7.67Control of coronary heart disease risk factors with doxazosin as monotherapy and in combination therapy. ( Rosenthal, J, 1988)
"Doxazosin, a selective alpha 1-inhibitor, was assessed in 34 patients with mild and moderate hypertension."7.67Doxazosin in the treatment of mild and moderate essential hypertension in general medical practice. ( van den Hogen, AL, 1988)
"Short- and long-term hemodynamic and clinical responses to sequential therapy with prazosin (15 mg/day for 3 to 12 weeks) and captopril (75 to 300 mg/day for 2 to 15 weeks) were compared in 22 patients with severe chronic congestive heart failure."7.67Comparative hemodynamic and clinical effects of long-term treatment with prazosin and captopril for severe chronic congestive heart failure secondary to coronary artery disease or idiopathic dilated cardiomyopathy. ( Medina, N; Packer, M; Yushak, M, 1986)
"The effect of prazosin in congestive heart failure was assessed in 10 patients (age 39--69) years) with ischemic heart disease or cardiomyopathy in functional class II-IV (NYHA)."7.66Acute hemodynamic and long-term clinical effects of prazosin in the treatment of chronic congestive heart failure. ( Lund-Johansen, P; Ohm, OJ; von der Lippe, G, 1981)
"We compared cardiocirculatory actions of nitroprusside (NP) to prazosin (PZ) in eleven chronic coronary patients with refractory congestive heart failure."7.66Comparison of effects of nitroprusside and prazosin on left ventricular function and the peripheral circulation in chronic refractory congestive heart failure. ( Awan, NA; Mason, DT; Miller, RR, 1978)
"Severe tachycardia, ventricular ectopy, and sodium retention manifested by hemodynamic deterioration developed with hydralazine hydrochloride therapy in chronic coronary heart disease with congestive failure refractory to digitalis, diuretics, and nitrates."7.66Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy. ( Amsterdam, EA; DeMaria, AN; Laslett, LJ; Mason, DT, 1978)
"The long-term efficacy of the new oral vasodilator, prazosin (PZ), was evaluated in nine patients with refractory heart failure due to chronic coronary heart disease."7.65Efficacy of ambulatory systemic vasodilator therapy with oral prazosin in chronic refractory heart failure. Concomitant relief of pulmonary congestion and elevation of pump output demonstrated by improvements in symptomatology, exercise tolerance, hemodyn ( Awan, NA; DeMaria, AN; Mason, DT; Maxwell, KS; Miller, RR; Neumann, A, 1977)
"Ischemia-induced arrhythmias were studied during a 30 min period of occlusion of the left anterior descending (LAD) coronary artery, and 100% of control animals (n = 24) exhibited ventricular tachycardia and 63% ventricular fibrillation."5.27Ischemia- and reperfusion-induced arrhythmias in conscious rats--studies with prazosin and atenolol. ( Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS, 1988)
" This result was not significant but suggested a favorable effect of terazosin on diminishing the risk of coronary heart disease."5.09[Evaluation of serum lipid levels in clinical benign prostatic hyperplasia patients with terazosin monotherapy]. ( Kageyama, S; Tamaki, M; Ueda, T, 1999)
" Forty-two patients, ages 42 to 65 years, including 21 men with sustained hypertension and elevated serum cholesterol levels, were included in a trial of monotherapy with doxazosin administered once daily (range, 1 to 16 mg)."5.07Efficacy and safety of doxazosin in the treatment of patients with mild or moderate essential hypertension and elevated levels of cholesterol. ( Taylor, SH, 1991)
"The antihypertensive efficacy and safety of doxazosin (once daily) and prazosin (twice daily) were compared in patients with mild or moderate essential hypertension (diastolic blood pressure [DBP] 95 to 114 mm Hg) not adequately controlled by diuretics and beta-blockers."5.07A double-blind comparative study of doxazosin and prazosin when administered with beta-blockers or diuretics. ( de Planque, BA, 1991)
"This study investigated the safety and efficacy of doxazosin treatment in a large population of patients (n = 336) with essential hypertension and assessed the effect of doxazosin on the serum lipid profile and the calculated risk of developing coronary heart disease."5.07Clinical experience with doxazosin in general medical practice in New Zealand. ( Maslowski, AH, 1991)
"This Latin American study assessed in the general practice setting the efficacy and tolerance of once-daily doxazosin in the treatment of mild or moderate essential hypertension (sitting diastolic blood pressure, 95 to 115 mm Hg)."5.07Doxazosin in the treatment of essential hypertension in general medical practice in Latin America. ( Fonseca, R; Marshall, D; Silva, H, 1991)
"This study was designed to assess the efficacy and tolerance of doxazosin in patients with mild, moderate, or severe essential hypertension in a general practice setting."5.07A multicenter study of doxazosin in the treatment of essential hypertension in France. ( Bonnet, G, 1991)
"This study was designed to investigate the efficacy and toleration of once-daily doxazosin in the treatment of essential hypertension (sitting diastolic blood pressure 95 to 115 mm Hg) in a general medical practice."5.07Clinical experience with doxazosin in general medical practice in The Netherlands. ( Harmse, DP, 1991)
"A single daily dose of doxazosin taken during a 12-week period produced a significant reduction in blood pressure and left ventricular mass index in patients with mild or moderate hypertension."5.07Echocardiographic assessment of doxazosin on left ventricular mass in patients with essential hypertension. ( Fonseca, R; López, B; Lugo de Franco, V; Medina, O; Monsalve, P; Ostojich, K; Pérez Acuña, F; Torres, N; Vera, O, 1991)
"The efficacy and toleration of doxazosin and atenolol were compared over a 52-week period in a double-blind, multicenter study of 228 patients with mild-to-moderate hypertension."5.06Comparison of the effects of doxazosin and atenolol on blood pressure and blood lipids: a one-year, double-blind study in 228 hypertensive patients. ( Daae, L; Talseth, T; Vatle, S; Westlie, L, 1988)
"Doxazosin is a selective alpha 1-inhibitor for the reduction of calculated coronary heart disease (CHD) risk in hypertensive patients."5.06Doxazosin versus atenolol: a randomized comparison of calculated coronary heart disease risk reduction. ( Guerrasio, E; Mazzola, C, 1988)
"Ten patients with severe chronic heart failure were given prazosin 5 mg and captopril 25 mg in random order on consecutive days."5.05Prazosin and captopril in chronic heart failure: comparison of acute haemodynamic and hormonal effects. ( Coxon, R; Sharpe, DN, 1982)
"Prazosin (Minipress) monotherapy was given to 152 patients with essential hypertension for one year in a multi-center study involving 13 hospitals and university clinics."3.68[The anti-lipidemic effect of Minipress]. ( Dudás, M; Farsang, C; Földes, I; Iványi, J; Pados, G, 1990)
"Oral prazosin hydrochloride (2-20 mg/day) was administered to 38 patients with chronic congestive heart failure due to ischemic heart disease for 6-18 months."3.68Prazosin in chronic congestive heart failure due to ischemic heart disease. ( Antani, JA; Antani, NJ; Nanivadekar, AS, 1991)
"Doxazosin, a selective alpha 1-inhibitor, was assessed in 34 patients with mild and moderate hypertension."3.67Doxazosin in the treatment of mild and moderate essential hypertension in general medical practice. ( van den Hogen, AL, 1988)
"The antihypertensive efficacy, lipid effects, and safety of doxazosin, a selective alpha 1-inhibitor for the reduction of coronary heart disease (CHD) risk in hypertensive patients, was assessed in a general medical practice setting."3.67Clinical experience with doxazosin in general medical practice. ( Rosenthal, J, 1988)
"Although the pathology of essential hypertension is still unclear, studies have shown that doxazosin, a selective alpha 1-inhibitor, is able to effectively control mild-to-moderate hypertension."3.67Control of coronary heart disease risk factors with doxazosin as monotherapy and in combination therapy. ( Rosenthal, J, 1988)
"Short- and long-term hemodynamic and clinical responses to sequential therapy with prazosin (15 mg/day for 3 to 12 weeks) and captopril (75 to 300 mg/day for 2 to 15 weeks) were compared in 22 patients with severe chronic congestive heart failure."3.67Comparative hemodynamic and clinical effects of long-term treatment with prazosin and captopril for severe chronic congestive heart failure secondary to coronary artery disease or idiopathic dilated cardiomyopathy. ( Medina, N; Packer, M; Yushak, M, 1986)
"The system release of prazosin confirms the good efficacy and tolerance of Alpress in the hypertension treatment."3.67[Efficacy, tolerance and incidence of risk factors of Alpress in the treatment of arterial hypertension]. ( Neimann, JL, 1989)
"Severe tachycardia, ventricular ectopy, and sodium retention manifested by hemodynamic deterioration developed with hydralazine hydrochloride therapy in chronic coronary heart disease with congestive failure refractory to digitalis, diuretics, and nitrates."3.66Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy. ( Amsterdam, EA; DeMaria, AN; Laslett, LJ; Mason, DT, 1978)
"We compared cardiocirculatory actions of nitroprusside (NP) to prazosin (PZ) in eleven chronic coronary patients with refractory congestive heart failure."3.66Comparison of effects of nitroprusside and prazosin on left ventricular function and the peripheral circulation in chronic refractory congestive heart failure. ( Awan, NA; Mason, DT; Miller, RR, 1978)
"The effect of prazosin in congestive heart failure was assessed in 10 patients (age 39--69) years) with ischemic heart disease or cardiomyopathy in functional class II-IV (NYHA)."3.66Acute hemodynamic and long-term clinical effects of prazosin in the treatment of chronic congestive heart failure. ( Lund-Johansen, P; Ohm, OJ; von der Lippe, G, 1981)
"The long-term efficacy of the new oral vasodilator, prazosin (PZ), was evaluated in nine patients with refractory heart failure due to chronic coronary heart disease."3.65Efficacy of ambulatory systemic vasodilator therapy with oral prazosin in chronic refractory heart failure. Concomitant relief of pulmonary congestion and elevation of pump output demonstrated by improvements in symptomatology, exercise tolerance, hemodyn ( Awan, NA; DeMaria, AN; Mason, DT; Maxwell, KS; Miller, RR; Neumann, A, 1977)
"Because coronary heart disease is known to have many causes, primary preventive therapy must logically go beyond the relatively simple goal of lowering blood pressure."2.66Effects of oral antihypertensive agents on blood lipid levels. ( Leren, P, 1986)
"Treatment with prazosin for one month also reduced systemic vascular resistance by 8%, renal vascular resistance increased by 20%, and renal blood flow and the percentage of the cardiac output going to the kidney fell by 14% and 26%."2.66The renal response to neuroendocrine inhibition in chronic heart failure: double-blind comparison of captopril and prazosin. ( Bayliss, J; Canepa-Anson, R; Norell, M; Poole-Wilson, P; Sutton, G, 1986)
" It is readily absorbed, with high bioavailability and a relatively long plasma half-life, neither of which property is influenced by age."2.38Clinical pharmacotherapeutics of doxazosin. ( Taylor, SH, 1989)
"Doxazosin appears to inhibit the development of CHD on two fronts."2.38Effects of doxazosin on serum lipids: a review of the clinical data and molecular basis for altered lipid metabolism. ( Pool, JL, 1991)
"When nifedipine was compared with isosorbide dinitrate in a randomized crossover, double-blind trial in patients with coronary artery spasm, both drugs were shown to be efficacious and neither was superior."2.37Large vessel coronary vasospasm: diagnosis, natural history and treatment. ( Conti, CR, 1985)
"An arterial stenosis that decreased coronary pressure to 40-42 mmHg resulted in a decrease of myocardial blood flow to 1."1.28Coronary arteriolar vasoconstriction in myocardial ischaemia: coronary vasodilator reserve during ischaemia. ( Bache, RJ; Laxson, DD, 1990)
"4."1.28Enhanced alpha-adrenoceptor responsiveness and receptor number during global ischaemia in the Langendorff perfused rat heart. ( Butterfield, MC; Chess-Williams, R, 1990)
"When adenosine release was attenuated by administration of prazosin (4 micrograms/kg/min i."1.28Endogenous adenosine blunts beta-adrenoceptor-mediated inotropic response in hypoperfused canine myocardium. ( Hori, M; Inoue, M; Kamada, T; Kitabatake, A; Kitakaze, M; Sato, H; Takashima, S, 1992)
" Phentolamine effected a partial dose-related inhibition of flow reductions; however, prazosin and yohimbine, given separately or in combination, failed to produce any significant effect despite an alpha-blocking action equivalent to or greater than that of phentolamine (alpha-agonist dose-response studies)."1.27Influence of alpha-adrenergic blockade on platelet-mediated thrombosis in stenosed canine coronary arteries. ( Bolli, R; Brandon, TA; Mace, ML; Weibaecher, DG, 1985)
"Systemic hypertension is a common clinical problem in the elderly."1.27Geriatric hypertension: antihypertensive therapy in coronary artery disease. ( Gonzalez, DG; Ram, CV, 1987)
"During coronary reperfusion, arrhythmias did not differ in control and treated groups."1.27Effect of alpha-adrenergic blockade on arrhythmias induced by acute myocardial ischemia and reperfusion in the dog. ( Bolli, R; Fisher, DJ; Miller, RR; Taylor, AA; Young, JB, 1984)
" These results show that the dose-response curve for the inhibitory effect of prazosin on Ca2+ overload is complex, and that adding prazosin coincident with the reperfusion of isolated ischaemic hearts does not attenuate Ca2+ gain."1.27The protective effect of prazosin on the ischaemic and reperfused myocardium. ( Gordon, M; Nayler, WG; Stephens, DJ; Sturrock, WJ, 1985)
"Prazosin treatment also prevented the delayed conduction of paced ventricular complexes entering and exiting the ischemic zone."1.27Electrophysiologic effects of prazosin during acute myocardial ischemia. ( Lucchesi, BR; Lynch, JJ; Wilber, DJ, 1986)
"Ischemia-induced arrhythmias were studied during a 30 min period of occlusion of the left anterior descending (LAD) coronary artery, and 100% of control animals (n = 24) exhibited ventricular tachycardia and 63% ventricular fibrillation."1.27Ischemia- and reperfusion-induced arrhythmias in conscious rats--studies with prazosin and atenolol. ( Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS, 1988)
"Initially, the pharmacologic treatment of hypertension consisted mostly of thiazide diuretics, since they were the only agents generally available that were well-tolerated by most patients."1.27Lipids and hypertension. Implications of new guidelines for cholesterol management in the treatment of hypertension. ( Grimm, RH; Hunninghake, DB, 1986)
"Protection from arrhythmias seems to be related to the combined presence of a noncompetitive adrenergic blockade associated with salutary effects on coronary circulation."1.27The effect of antiarrhythmic drugs on life-threatening arrhythmias induced by the interaction between acute myocardial ischemia and sympathetic hyperactivity. ( Schwartz, PJ; Vanoli, E; Zaza, A; Zuanetti, G, 1985)
"With prazosin there was a reduction in ventricular filling pressures and rate-pressure product but no change in coronary sinus flow or MVO2."1.26Vasodilators in heart failure secondary to coronary artery disease. ( Chatterjee, K; Parmley, WW; Rouleau, JL, 1982)

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-199080 (70.18)18.7374
1990's34 (29.82)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leren, P2
Foss, PO1
Helgeland, A1
Hjermann, I1
Holme, I2
Lund-Larsen, PG1
Thandroyen, FT1
Worthington, MG1
Higginson, LM1
Opie, LH2
Heinecker, R1
Sharma, AD1
Saffitz, JE1
Lee, BI1
Sobel, BE1
Corr, PB2
Shevchenko, VA1
Lowenstein, J1
Bolli, R2
Fisher, DJ1
Taylor, AA2
Young, JB1
Miller, RR3
Shayman, JA1
Kramer, JB1
Kipnis, RJ1
Ram, CV2
Manno, BV1
Iskandrian, AS1
Hakki, AH1
Bolte, HD1
Bush, LR1
Campbell, WB1
Kern, K1
Tilton, GD1
Apprill, P1
Ashton, J1
Schmitz, J1
Buja, LM1
Willerson, JT1
Benfey, BG1
Elfellah, MS1
Ogilvie, RI1
Varma, DR1
Sharpe, DN1
Coxon, R1
Klein, W1
Goebel, R1
Heusch, G2
Deussen, A1
Chatterjee, K3
Rouleau, JL3
Benge, W1
Parmley, WW2
Hiramatsu, B1
Młyński, J1
Silke, B2
Taylor, SH5
von der Lippe, G1
Ohm, OJ1
Lund-Johansen, P1
Hendry, WG1
Krishnan, S1
Levy, MN1
Tamaki, M1
Ueda, T1
Kageyama, S1
Bartolo, M1
Pittorino, L1
Di Lorenzo, M1
Ricci, G1
Awan, NA2
Mason, DT3
Laslett, LJ1
DeMaria, AN2
Amsterdam, EA1
Timio, M1
Gentili, S1
Pede, S1
Schiaroli, M1
Maxwell, KS1
Neumann, A1
Sato, H1
Hori, M2
Kitakaze, M2
Takashima, S1
Inoue, M1
Kitabatake, A2
Kamada, T2
Piatak, OA1
Yanovskii, GV1
Lizogub, VG1
de Planque, BA1
Grimm, RH2
McInnes, GT1
Passarelli, P1
Galiè, N1
Limonetti, P1
Branzi, A1
Magnani, B1
Westby, J3
Hexeberg, E1
Olweus, J1
Myking, OL1
Lekven, J3
Grong, K3
Antani, JA1
Antani, NJ1
Nanivadekar, AS1
Pool, JL2
Fauchald, P1
Rugstad, HE1
Stokke, HP1
Langdon, CG1
Naber, FB1
Talseth, T2
Westlie, L2
Daae, L2
Wessels, F1
Maslowski, AH1
Silva, H1
Fonseca, R2
Marshall, D1
Bonnet, G1
Harmse, DP1
Monsalve, P1
Vera, O1
Pérez Acuña, F1
Medina, O1
Ostojich, K1
López, B1
Torres, N1
Lugo de Franco, V1
Hernandez Hernandez, R1
Guerrero Pajuelo, JR1
Carvajal, AR1
Armas Padilla, MC1
Armas de Hernandez, MJ1
Barragan, O1
Boada Boada, JJ1
Kaneko, M1
Hayashi, H1
Kobayashi, A1
Yamazaki, N1
Dhalla, NS1
Kvitting, P2
Birkeland, S2
Bache, RJ2
Laxson, DD2
Lenz, ML1
Seitelberger, R1
Guth, BD1
Ross, J1
Rouffy, J1
Butterfield, MC1
Chess-Williams, R1
Kawai, T1
Okumura, K1
Hashimoto, H1
Ito, T1
Satake, T1
Pados, G1
Iványi, J1
Földes, I1
Dudás, M1
Farsang, C1
Mohanlal, RW1
Mauve, I1
van der Valk, L1
Bruschke, AV1
van der Laarse, A1
Galassi, AR1
Kaski, JC1
Pupita, G1
Vejar, M1
Crea, F1
Maseri, A1
Dai, XZ1
Homans, DC1
Manning, AS2
Crome, R1
Klein, N1
Hearse, DJ2
Maguire, ME1
Graham, RM1
Rosenthal, J3
Neimann, JL1
Rockhold, FW1
Goldberg, MR1
Thompson, WL1
Burduli, FU1
Khadzhidis, PK1
Vatsadze, TG1
Tabidze, GA1
Tamai, J1
Iwakura, K1
Gotoh, K1
Iwai, K1
Koretsune, Y1
Kagiya, T1
Shiga, T1
Nakazawa, M1
Imai, S1
Dillon, JS1
Gu, XH1
Nayler, WG2
Conti, CR1
Moulds, RF1
Brandon, TA1
Mace, ML1
Weibaecher, DG1
Davey, MJ1
Sheridan, DJ1
Gonzalez, DG1
van den Hogen, AL1
Bartels, AC1
de Vries, PM1
Oe, LP1
van Bronswÿk, H1
Donker, AJ1
Réveillaud, RJ1
Fillastre, JP1
Zech, P1
Castrignano, R1
D'Angelo, A1
Pati, T1
Al Awady, M1
Tronca, R1
Crepaldi, G1
Vatle, S1
Mazzola, C1
Guerrasio, E1
Nechwatal, W1
Berger, J1
Blumrich, W1
Bouzo, H1
Brandl, K1
Braun, S1
Laukaitis, A1
Müller, G1
Ryba, W1
Schreiegg, J1
Lindner, UK1
von Manteuffel, GE1
Stafunsky, M1
Englert, RG1
Mauersberger, H1
Hansson, L1
Gordon, M1
Stephens, DJ1
Sturrock, WJ1
Wilber, DJ1
Lynch, JJ1
Lucchesi, BR1
Urbaszek, W1
Graf, B1
Bölter, C1
Zingler, C1
Mekat, A1
Nabel, HJ1
Ernst, B1
Kinoshita, K1
Braimbridge, MV1
Hagestad, EL1
Verrier, RL1
Packer, M1
Medina, N1
Yushak, M1
Bayliss, J2
Canepa-Anson, R2
Norell, M1
Poole-Wilson, P2
Sutton, G2
Schwartz, PJ2
Vanoli, E2
Norell, MS1
Reid, C1
Hunninghake, DB1
Zaza, A1
Zuanetti, G1

Reviews

14 reviews available for prazosin and Coronary Disease

ArticleYear
[Treatment of heart failure in ischemic heart disease with beta-adrenostimulators and peripheral vasodilators].
    Vrachebnoe delo, 1983, Issue:10

    Topics: Adrenergic beta-Agonists; Captopril; Cardiotonic Agents; Coronary Disease; Dobutamine; Dopamine; Hea

1983
Hypertensive crisis.
    Cardiology clinics, 1984, Volume: 2, Issue:2

    Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia

1984
Right ventricular function: methodologic and clinical considerations in noninvasive scintigraphic assessment.
    Journal of the American College of Cardiology, 1984, Volume: 3, Issue:4

    Topics: Animals; Captopril; Coronary Disease; Echocardiography; Heart; Heart Defects, Congenital; Heart Vent

1984
[Treatment of heart failure with vasodilators].
    Der Internist, 1980, Volume: 21, Issue:12

    Topics: Captopril; Cardiomegaly; Cardiotonic Agents; Coronary Disease; Heart Failure; Heart Function Tests;

1980
Antihypertensive therapy: taking lipids into consideration.
    American heart journal, 1991, Volume: 122, Issue:3 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors;

1991
The value of alpha-blockers in the management of hypertension: a practical view.
    Journal of human hypertension, 1991, Volume: 5, Issue:4

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Blood Pressure; Coronary Disease; Doxazosin;

1991
Effects of doxazosin on serum lipids: a review of the clinical data and molecular basis for altered lipid metabolism.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Cholesterol; Clinical Trials as Topic; Coronary Disease; Doxazosin; Humans;

1991
Clinical pharmacotherapeutics of doxazosin.
    The American journal of medicine, 1989, Aug-16, Volume: 87, Issue:2A

    Topics: Adrenergic alpha-Antagonists; Coronary Disease; Doxazosin; Hemodynamics; Humans; Hypertension; Prazo

1989
Selective alpha 1-adrenergic blockade, lipids, and coronary heart disease risk. Considerations in the treatment of mild hypertension.
    The American journal of medicine, 1989, Aug-16, Volume: 87, Issue:2A

    Topics: Adrenergic alpha-Antagonists; Coronary Disease; Humans; Hypertension; Lipids; Prazosin; Risk Factors

1989
Blood pressure and lipid lowering effects of terazosin.
    Journal of human hypertension, 1989, Volume: 3 Suppl 2

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Blood Pressure; Coronary Disease; Humans; Hyp

1989
Large vessel coronary vasospasm: diagnosis, natural history and treatment.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aspirin; Coronary Artery Bypass; Coronary

1985
Alpha adrenoceptors--an overview.
    Journal of molecular and cellular cardiology, 1986, Volume: 18 Suppl 5

    Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Catecholamines; Child, Preschool; Coron

1986
Pharmacotherapeutic stature of doxazosin and its role in coronary risk reduction.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Coronary Disease; Dose-Response Relationship,

1988
Implications of doxazosin therapy on risk of coronary heart disease.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Coronary Disease; Doxazosin; Humans; Lipoprot

1988

Trials

28 trials available for prazosin and Coronary Disease

ArticleYear
Effect of propranolol and prazosin on blood lipids. The Oslo Study.
    Lancet (London, England), 1980, Jul-05, Volume: 2, Issue:8184

    Topics: Cerebrovascular Disorders; Cholesterol; Coronary Disease; Drug Antagonism; Drug Therapy, Combination

1980
Prazosin and captopril in chronic heart failure: comparison of acute haemodynamic and hormonal effects.
    Australian and New Zealand journal of medicine, 1982, Volume: 12, Issue:5

    Topics: Aged; Aldosterone; Blood Pressure; Captopril; Chronic Disease; Clinical Trials as Topic; Coronary Di

1982
Alterations in left ventricular function and coronary hemodynamics with captopril, hydralazine and prazosin in chronic ischemic heart failure: a comparative study.
    Circulation, 1982, Volume: 65, Issue:4

    Topics: Aged; Captopril; Coronary Disease; Dose-Response Relationship, Drug; Heart Failure; Hemodynamics; Hu

1982
[Evaluation of serum lipid levels in clinical benign prostatic hyperplasia patients with terazosin monotherapy].
    Hinyokika kiyo. Acta urologica Japonica, 1999, Volume: 45, Issue:12

    Topics: Aged; Coronary Disease; Humans; Hyperlipidemias; Lipids; Male; Middle Aged; Prazosin; Prostatic Hype

1999
The influence of adrenoreactive preparations on clinical and haemodynamic parameters in patients with ischaemic heart disease.
    Cor et vasa, 1991, Volume: 33, Issue:1

    Topics: Adult; Angina Pectoris; Coronary Artery Disease; Coronary Disease; Double-Blind Method; Exercise Tes

1991
A double-blind comparative study of doxazosin and prazosin when administered with beta-blockers or diuretics.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Coronary Disease; Diuretics; Double-Blind Meth

1991
[Comparative effects of doxazosin and enalapril in patients with arterial hypertension and exercise-induced acute myocardial ischemia].
    Cardiologia (Rome, Italy), 1991, Volume: 36, Issue:10

    Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Coronary Disease; Doxazosin; Enalapril;

1991
Preliminary results of the Norwegian doxazosin postmarketing surveillance study: a twelve-week experience.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Blood Pressure; Cholesterol; Coronary Disease; Doxazosin; Female; Heart Rat

1991
Doxazosin: a study in a cohort of patients with hypertension in general practice--an interim report.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Cholesterol; Cohort Studies; Coronary Disease; Doxazosin; England; Family P

1991
An open, noncomparative study of doxazosin in essential hypertension: experience in general practice in The Netherlands.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Cholesterol; Coronary Disease; Doxazosin; Family Practice; Female; Humans;

1991
Doxazosin and atenolol as monotherapy in mild and moderate hypertension: a randomized, parallel study with a three-year follow-up.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Atenolol; Cholesterol; Coronary Disease; Double-Blind Method; Doxazosin; Fe

1991
Double-blind comparison of doxazosin and enalapril in patients with mild or moderate essential hypertension.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Coronary Disease; Double-Blind Method; Doxazosin; Enalapril; Family Practic

1991
Clinical experience with doxazosin in general medical practice in New Zealand.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Cholesterol; Coronary Disease; Doxazosin; Family Practice; Female; Humans;

1991
Doxazosin in the treatment of essential hypertension in general medical practice in Latin America.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Argentina; Cholesterol; Coronary Disease; Doxazosin; Family Practice; Femal

1991
A multicenter study of doxazosin in the treatment of essential hypertension in France.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Cholesterol; Coronary Disease; Doxazosin; Family Practice; Female; France;

1991
Clinical experience with doxazosin in general medical practice in The Netherlands.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Cholesterol; Coronary Disease; Doxazosin; Family Practice; Female; Humans;

1991
Echocardiographic assessment of doxazosin on left ventricular mass in patients with essential hypertension.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Cardiomegaly; Cholesterol; Coronary Disease; Doxazosin; Echocardiography; F

1991
Efficacy and safety of doxazosin in the treatment of patients with mild or moderate essential hypertension and elevated levels of cholesterol.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Cholesterol; Coronary Disease; Doxazosin; England; Female; Humans; Hyperten

1991
Evidence of an antiplatelet aggregation action of doxazosin in patients with hypertension: an ex vivo study.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Cholesterol; Coronary Disease; Dose-Response Relationship, Drug; Doxazosin;

1991
[Alpha-1 inhibition. Prevention of coronary risk factors].
    Annales de cardiologie et d'angeiologie, 1990, Dec-30, Volume: 39, Issue:10 ( Pt 2)

    Topics: Atenolol; Coronary Disease; Delayed-Action Preparations; Female; Humans; Hypertension; Lipids; Male;

1990
Beneficial effects of pinacidil on blood lipids: comparisons with prazosin and placebo in patients with hypertension. Pinacidil-Prazosin and Pinacidil-Placebo Research Groups, Lilly Research Laboratories.
    The Journal of laboratory and clinical medicine, 1989, Volume: 114, Issue:6

    Topics: Antihypertensive Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic;

1989
[Use of prazosin and capoten in the treatment of heart failure in patients with ischemic heart disease].
    Kardiologiia, 1989, Volume: 29, Issue:9

    Topics: Adult; Captopril; Cardiomyopathy, Dilated; Clinical Trials as Topic; Coronary Disease; Hemodynamics;

1989
Effects of oral antihypertensive agents on blood lipid levels.
    Clinical therapeutics, 1986, Volume: 8, Issue:3

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Cl

1986
Comparison of the effects of doxazosin and atenolol on blood pressure and blood lipids: a one-year, double-blind study in 228 hypertensive patients.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Coronary D

1988
Doxazosin versus atenolol: a randomized comparison of calculated coronary heart disease risk reduction.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pres

1988
A double-blind comparative study of doxazosin and nitrendipine in patients with mild-to-moderate essential hypertension.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease

1988
The renal response to neuroendocrine inhibition in chronic heart failure: double-blind comparison of captopril and prazosin.
    European heart journal, 1986, Volume: 7, Issue:10

    Topics: Aged; Aldosterone; Captopril; Cardiac Output; Cardiomyopathy, Dilated; Coronary Disease; Double-Blin

1986
Clinical importance of the renin-angiotensin system in chronic heart failure: double blind comparison of captopril and prazosin.
    British medical journal (Clinical research ed.), 1985, Jun-22, Volume: 290, Issue:6485

    Topics: Aged; Captopril; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; F

1985

Other Studies

72 other studies available for prazosin and Coronary Disease

ArticleYear
Antihypertensive drugs, plasma lipids, and coronary disease.
    Lancet (London, England), 1980, Jul-05, Volume: 2, Issue:8184

    Topics: Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Coronary Disease; Drug Antagonis

1980
The effect of alpha- and beta-adrenoceptor antagonist agents on reperfusion ventricular fibrillation and metabolic status in the isolated perfused rat heart.
    Journal of the American College of Cardiology, 1983, Volume: 1, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arterial Occlusive Diseases; Ate

1983
[Frequent errors in the therapy of heart disease].
    Wiener medizinische Wochenschrift (1946), 1982, Nov-30, Volume: 132, Issue:22

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biologic

1982
Alpha adrenergic-mediated accumulation of calcium in reperfused myocardium.
    The Journal of clinical investigation, 1983, Volume: 72, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium; C

1983
Effects of prazosin on serum lipids in patients with essential hypertension: a review of the findings presented at the Satellite Symposium on coronary heart disease: hypertension and other risk factors, Milan, 1983.
    The American journal of cardiology, 1984, Jan-27, Volume: 53, Issue:3

    Topics: Adrenergic beta-Antagonists; Benzothiadiazines; Chlorthalidone; Cholesterol; Cholesterol, HDL; Coron

1984
Calcium ions, drug action and the heart--with special reference to calcium antagonist drugs.
    Pharmacology & therapeutics, 1984, Volume: 25, Issue:3

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channe

1984
Effect of alpha-adrenergic blockade on arrhythmias induced by acute myocardial ischemia and reperfusion in the dog.
    Journal of molecular and cellular cardiology, 1984, Volume: 16, Issue:12

    Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Coronar

1984
Increased alpha-adrenergic receptors in ischemic cat myocardium. A potential mediator of electrophysiological derangements.
    The Journal of clinical investigation, 1981, Volume: 67, Issue:4

    Topics: Animals; Cats; Coronary Disease; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Rece

1981
The effects of alpha 2-adrenergic and serotonergic receptor antagonists on cyclic blood flow alterations in stenosed canine coronary arteries.
    Circulation research, 1984, Volume: 55, Issue:5

    Topics: Adenosine Diphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Disease; Dogs; F

1984
Coronary heart disease: hypertension and other risk factors. Proceedings of a satellite symposium of the first European Meeting on Hypertension.
    The American journal of medicine, 1984, Feb-27, Volume: 76, Issue:2A

    Topics: Coronary Disease; Humans; Hypertension; Lipid Metabolism; Prazosin; Risk

1984
Anti-arrhythmic effects of prazosin and propranolol during coronary artery occlusion and re-perfusion in dogs and pigs.
    British journal of pharmacology, 1984, Volume: 82, Issue:3

    Topics: Animals; Arterial Occlusive Diseases; Blood Pressure; Coronary Disease; Dogs; Drug Therapy, Combinat

1984
[Effects of acute and chronic vasodilator administration on hemodynamics and catecholamine concentration in chronic left heart failure (author's transl)].
    Zeitschrift fur Kardiologie, 1980, Volume: 69, Issue:2

    Topics: Blood Pressure; Cardiac Output; Cardiomyopathies; Catecholamines; Coronary Disease; Dopamine; Epinep

1980
The effects of cardiac sympathetic nerve stimulation on perfusion of stenotic coronary arteries in the dog.
    Circulation research, 1983, Volume: 53, Issue:1

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Electric Stimulation; Heart

1983
Hemodynamic and metabolic effects of vasodilators, nitrates, hydralazine, prazosin and captopril in chronic ischemic heart failure.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 651

    Topics: Captopril; Coronary Disease; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Lactates; Myoc

1981
Vasodilators in heart failure secondary to coronary artery disease.
    American heart journal, 1982, Volume: 103, Issue:4 Pt 2

    Topics: Cardiac Output; Coronary Disease; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Myocardi

1982
[Effect of prazosin on changes in blood lipids].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Nov-15, Volume: 37, Issue:44

    Topics: Coronary Disease; Humans; Hyperlipoproteinemia Type IV; Hypertension; Lipoproteins, HDL; Lipoprotein

1982
Pharmacokinetic and haemodynamic studies with prazosin in chronic heart failure.
    Irish journal of medical science, 1981, Volume: 150, Issue:8

    Topics: Aged; Blood Pressure; Chronic Disease; Coronary Disease; Electrocardiography; Exercise Test; Female;

1981
Acute hemodynamic and long-term clinical effects of prazosin in the treatment of chronic congestive heart failure.
    Acta medica Scandinavica, 1981, Volume: 210, Issue:3

    Topics: Adult; Aged; Coronary Disease; Female; Follow-Up Studies; Heart Failure; Hemodynamics; Humans; Male;

1981
Immediate and sustained haemodynamic effects of prazosin during upright exercise in man.
    British heart journal, 1981, Volume: 46, Issue:6

    Topics: Coronary Disease; Hemodynamics; Humans; Physical Exertion; Prazosin; Quinazolines

1981
Effects of coronary artery occlusion and reperfusion on the idioventricular rate in anesthetized dogs.
    Journal of the American College of Cardiology, 1994, Volume: 23, Issue:6

    Topics: Analysis of Variance; Animals; Coronary Disease; Disease Models, Animal; Dogs; Heart Block; Heart Ra

1994
The role of prazosin in the management of hypertension.
    The Medical journal of Australia, 1977, Aug-27, Volume: 2, Issue:2 Suppl

    Topics: Adolescent; Adrenergic beta-Antagonists; Anesthesia, General; Child; Coronary Disease; Diuretics; Dr

1977
[Flow measurement characteristics in heart patients after the acute and protracted administration of 2 vasoactive drugs: prazosin hydrochloride and isosorbide dinitrate].
    Bollettino della Societa italiana di cardiologia, 1979, Volume: 24, Issue:9

    Topics: Blood Circulation; Coronary Disease; Humans; Hyperemia; Isosorbide Dinitrate; Prazosin; Quinazolines

1979
Comparison of effects of nitroprusside and prazosin on left ventricular function and the peripheral circulation in chronic refractory congestive heart failure.
    Circulation, 1978, Volume: 57, Issue:1

    Topics: Adult; Aged; Blood Circulation; Coronary Disease; Female; Ferricyanides; Heart Failure; Heart Rate;

1978
Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy.
    Archives of internal medicine, 1978, Volume: 138, Issue:5

    Topics: Aged; Coronary Disease; Digitalis Glycosides; Female; Furosemide; Heart Failure; Humans; Hydralazine

1978
[Prazosin in refractory congestive heart failure].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:4

    Topics: Adult; Aged; Coronary Disease; Digitalis Glycosides; Diuretics; Heart Failure; Humans; Male; Middle

1978
Efficacy of ambulatory systemic vasodilator therapy with oral prazosin in chronic refractory heart failure. Concomitant relief of pulmonary congestion and elevation of pump output demonstrated by improvements in symptomatology, exercise tolerance, hemodyn
    Circulation, 1977, Volume: 56, Issue:3

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Blood Pressure; Cardiac Output; Chronic Disease;

1977
Endogenous adenosine blunts beta-adrenoceptor-mediated inotropic response in hypoperfused canine myocardium.
    Circulation, 1992, Volume: 85, Issue:4

    Topics: Adenosine; Animals; Coronary Disease; Dogs; Heart; Isoproterenol; Myocardial Contraction; Prazosin;

1992
Management of coronary heart disease risk factors in hypertensive patients: clinical experience with doxazosin. A symposium. London, England, January 26, 1990. Proceedings.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Coronary Disease; Doxazosin; Humans; Hypertension; Prazosin; Risk Factors

1991
Blood flow regulation during acute regional ischemia in feline hearts: importance of postjunctional alpha 1- and alpha 2-adrenoceptors.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Catecholamines; Cats; Coronary Circulation; Cor

1991
Prazosin in chronic congestive heart failure due to ischemic heart disease.
    Clinical cardiology, 1991, Volume: 14, Issue:6

    Topics: Aged; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Female; Follow-Up

1991
Stunned myocardium and oxygen free radicals--sarcolemmal membrane damage due to oxygen free radicals.
    Japanese circulation journal, 1991, Volume: 55, Issue:9

    Topics: Adenosine Triphosphatases; Animals; Calcium; Catalase; Cell Membrane; Coronary Disease; Free Radical

1991
Regional perfusion in hearts with acute coronary artery occlusion and subsequent beta 2- and alpha 1-adrenergic blockade.
    Clinical physiology (Oxford, England), 1990, Volume: 10, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cats; Coronary Circulation; Coro

1990
Coronary arteriolar vasoconstriction in myocardial ischaemia: coronary vasodilator reserve during ischaemia.
    European heart journal, 1990, Volume: 11 Suppl B

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Constriction, Pathologic; Coronary Circulatio

1990
Hypertension, coronary risk and alpha-blockade.
    Journal of human hypertension, 1990, Volume: 4 Suppl 3

    Topics: Adrenergic alpha-Antagonists; Coronary Disease; Doxazosin; Humans; Hypertension; Prazosin; Risk Fact

1990
Alpha 1-adrenoreceptor blockade and the molecular basis of lipid metabolism alterations.
    Journal of human hypertension, 1990, Volume: 4 Suppl 3

    Topics: Adrenergic alpha-Antagonists; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Dox

1990
Alpha 2-adrenergic coronary constriction in ischemic myocardium during exercise.
    Basic research in cardiology, 1990, Volume: 85 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Disease;

1990
Enhanced alpha-adrenoceptor responsiveness and receptor number during global ischaemia in the Langendorff perfused rat heart.
    British journal of pharmacology, 1990, Volume: 100, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Binding Sites; Coronary Disease; Heart Rate;

1990
Alteration of 1,2-diacylglycerol content in ischemic and reperfused heart.
    Molecular and cellular biochemistry, 1990, Dec-03, Volume: 99, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Diglycerides; Dogs; Kinetics; Male; Myocardial Repe

1990
[The anti-lipidemic effect of Minipress].
    Orvosi hetilap, 1990, May-27, Volume: 131, Issue:21

    Topics: Coronary Disease; Drug Evaluation; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertension; Hypo

1990
Does alpha 1-adrenergic blockade influence regional blood flow regulation in hearts with coronary artery occlusion?
    Clinical physiology (Oxford, England), 1989, Volume: 9, Issue:2

    Topics: Animals; Atenolol; Cats; Coronary Circulation; Coronary Disease; Doxazosin; Female; Male; Prazosin;

1989
Delayed recovery of homogeneous perfusion distribution in isolated rat heart after vasodilatation induced by alpha 1 adrenoceptor blockade during postischaemic reperfusion.
    Cardiovascular research, 1989, Volume: 23, Issue:11

    Topics: Animals; Blood Flow Velocity; Coronary Circulation; Coronary Disease; Doxazosin; L-Lactate Dehydroge

1989
Lack of evidence for alpha-adrenergic receptor-mediated mechanisms in the genesis of ischemia in syndrome X.
    The American journal of cardiology, 1989, Aug-01, Volume: 64, Issue:5

    Topics: Adult; Angina Pectoris; Clonidine; Coronary Angiography; Coronary Disease; Electrocardiography; Exer

1989
The role of alpha 1- and alpha 2-adrenergic receptors in mediation of coronary vasoconstriction in hypoperfused ischemic myocardium during exercise.
    Circulation research, 1989, Volume: 65, Issue:6

    Topics: Animals; Coronary Circulation; Coronary Disease; Dioxanes; Dogs; Female; Hemodynamics; Idazoxan; Mal

1989
Dissociation between reperfusion induced arrhythmias and increases in ventricular alpha 1 receptor density in the anaesthetised rat.
    Cardiovascular research, 1989, Volume: 23, Issue:10

    Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Heart Ventricles; Male; Myocardial Reperfusion Inju

1989
Alpha-blockade for hypertension: indifferent past, uncertain future.
    Lancet (London, England), 1989, May-13, Volume: 1, Issue:8646

    Topics: Antihypertensive Agents; Coronary Disease; Doxazosin; Drug Evaluation; Humans; Hypertension; Prazosi

1989
[Efficacy, tolerance and incidence of risk factors of Alpress in the treatment of arterial hypertension].
    Annales de cardiologie et d'angeiologie, 1989, Dec-15, Volume: 38, Issue:9 Pt 2

    Topics: Adult; Aged; Coronary Disease; Delayed-Action Preparations; Drug Evaluation; Female; Humans; Hyperte

1989
Adenosine-induced hyperemia attenuates myocardial ischemia in coronary microembolization in dogs.
    The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 2

    Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Embolism; Microspheres; Myocardium

1989
Ventricular pressure-heart rate product before induction of ischemia as a determinant of the reperfusion-induced accumulation of calcium within myocardium.
    Japanese journal of pharmacology, 1987, Volume: 45, Issue:3

    Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Coronary Disease; Cyclic AMP; Guinea Pig

1987
Alpha 1 adrenoceptors in the ischaemic and reperfused myocardium.
    Journal of molecular and cellular cardiology, 1988, Volume: 20, Issue:8

    Topics: Aerobiosis; Animals; Binding, Competitive; Cell Membrane; Coronary Disease; Kinetics; Male; Myocardi

1988
Clinical pharmacology of vasodilator drugs.
    The Medical journal of Australia, 1985, Apr-01, Volume: 142, Issue:7

    Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Coronary Disease; Humans; Hydralazine; Hyper

1985
Influence of alpha-adrenergic blockade on platelet-mediated thrombosis in stenosed canine coronary arteries.
    Cardiovascular research, 1985, Volume: 19, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Flow Velocity; Blood Platelets; Blood Pressure; Coronar

1985
[Reduction of coronary risk factors with selective alpha-blockers. International Doxazosin Symposium. Frankfurt/Main, 7 June 1986].
    Fortschritte der Medizin. Supplement : die Kongressinformation fur die Praxis, 1986, Volume: 8

    Topics: Adrenergic alpha-Antagonists; Coronary Disease; Doxazosin; Humans; Prazosin; Risk

1986
Alpha adrenoceptors and arrhythmias.
    Journal of molecular and cellular cardiology, 1986, Volume: 18 Suppl 5

    Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Guine

1986
Geriatric hypertension: antihypertensive therapy in coronary artery disease.
    Geriatrics, 1987, Volume: 42, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blocker

1987
Doxazosin in the treatment of mild and moderate essential hypertension in general medical practice.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease

1988
Clinical experience with doxazosin in general medical practice.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease

1988
Control of coronary heart disease risk factors with doxazosin as monotherapy and in combination therapy.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Coronary Disease; Doxazosin; Dru

1988
Doxazosin in the treatment of patients with mild or moderate hypertension and mild or moderate renal insufficiency.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease

1988
A single-blind study of doxazosin in the treatment of mild-to-moderate essential hypertensive patients with concomitant noninsulin-dependent diabetes mellitus.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease

1988
The addition of doxazosin to the treatment regimen of hypertensive patients not responsive to nifedipine.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease

1988
A single-blind study of doxazosin in the treatment of essential hypertension when added to nonresponders to angiotensin-converting enzyme inhibitor therapy.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensiv

1988
A symposium: Doxazosin: coronary artery disease risk factor management. June 7, 1986, Frankfurt, Germany.
    The American journal of cardiology, 1987, May-29, Volume: 59, Issue:14

    Topics: Antihypertensive Agents; Coronary Disease; Doxazosin; Humans; Hypertension; Prazosin; Risk

1987
Doxazosin: A distinctive approach to risk reduction of coronary heart disease in hypertensive patients. Proceedings of a symposium. Hamburg, West Germany, January 30, 1988.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Antihypertensive Agents; Coronary Disease; Doxazosin; Humans; Hypertension; Prazosin; Risk Factors

1988
The protective effect of prazosin on the ischaemic and reperfused myocardium.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:7

    Topics: Adenosine Triphosphate; Animals; Calcium; Coronary Disease; Diltiazem; Male; Myocardial Contraction;

1985
Electrophysiologic effects of prazosin during acute myocardial ischemia.
    European journal of pharmacology, 1986, Aug-07, Volume: 127, Issue:1-2

    Topics: Animals; Coronary Disease; Dogs; Electrophysiology; Male; Prazosin; Receptors, Adrenergic, alpha; Ve

1986
[The status of prazosin in therapy of chronic heart failure].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1988, Nov-01, Volume: 43, Issue:21

    Topics: Cardiomyopathy, Dilated; Coronary Disease; Drug Therapy, Combination; Heart Failure; Heart Valve Dis

1988
Ischemia- and reperfusion-induced arrhythmias in conscious rats--studies with prazosin and atenolol.
    Japanese circulation journal, 1988, Volume: 52, Issue:12

    Topics: Animals; Arrhythmias, Cardiac; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Male; Myocard

1988
Delayed myocardial ischemia following the cessation of sympathetic stimulation.
    American heart journal, 1988, Volume: 115, Issue:1 Pt 1

    Topics: Animals; Coronary Disease; Dogs; Electric Stimulation; Hemodynamics; Nifedipine; Prazosin; Stellate

1988
Comparative hemodynamic and clinical effects of long-term treatment with prazosin and captopril for severe chronic congestive heart failure secondary to coronary artery disease or idiopathic dilated cardiomyopathy.
    The American journal of cardiology, 1986, Jun-01, Volume: 57, Issue:15

    Topics: Adult; Aged; Captopril; Cardiomyopathy, Dilated; Coronary Disease; Female; Heart Failure; Hemodynami

1986
An experimental approach to the choice of antiarrhythmic therapy.
    European heart journal, 1986, Volume: 7 Suppl A

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Diltiazem

1986
Lipids and hypertension. Implications of new guidelines for cholesterol management in the treatment of hypertension.
    The American journal of medicine, 1986, Feb-14, Volume: 80, Issue:2A

    Topics: Adolescent; Adult; Child; Child, Preschool; Cholesterol; Cholestyramine Resin; Coronary Disease; Die

1986
The effect of antiarrhythmic drugs on life-threatening arrhythmias induced by the interaction between acute myocardial ischemia and sympathetic hyperactivity.
    American heart journal, 1985, Volume: 109, Issue:5 Pt 1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Disease M

1985