prazosin has been researched along with Cold Fingers, Hereditary in 28 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prazosin, an orally active alpha-1 selective adrenergic antagonist, has been of value in treating patients with hypertension and congestive heart failure." | 8.76 | Alpha-adrenergic receptor blockade with prazosin. Consideration of hypertension, heart failure, and potential new applications. ( Colucci, WS, 1982) |
| "Prazosin, an orally active alpha-1 selective adrenergic antagonist, has been of value in treating patients with hypertension and congestive heart failure." | 4.76 | Alpha-adrenergic receptor blockade with prazosin. Consideration of hypertension, heart failure, and potential new applications. ( Colucci, WS, 1982) |
| "Idiopathic Raynaud's disease is characterized by cold-induced digital vasospasms, but its origin has not been established." | 2.68 | Blockade of vasospastic attacks by alpha 2-adrenergic but not alpha 1-adrenergic antagonists in idiopathic Raynaud's disease. ( Baer, RP; Freedman, RR; Mayes, MD, 1995) |
| "Raynaud's disease is characterized by excessive cutaneous vasoconstriction in response to ambient cold." | 2.68 | Role of digital artery adrenoceptors in Raynaud's disease. ( Beetham, WP; Cooke, JP; Creager, MA; Creager, SJ; Ren, C; Scales, KM; Tsapatsaris, NP, 1997) |
| " In the higher dosage ranges, spontaneous mentioned side effects were noticed most often, which was in accordance with the results of a checklist analysis on adverse effects." | 2.66 | Dose-response study of prazosin in Raynaud's phenomenon: clinical effectiveness versus side effects. ( Thien, T; Wollersheim, H, 1988) |
| "Prazosin was shown to be effective in reducing both the frequency and the severity of vasospasm reported by the patients." | 2.65 | A double-blind study of prazosin in the treatment of Raynaud's phenomenon in scleroderma. ( Allen, LM; Duvic, M; Gilgor, RS; Surwit, RS, 1984) |
| "Prazosin has been found in two randomized controlled cross-over trials to be more effective than placebo in the treatment of Raynaud's secondary to scleroderma." | 2.41 | Prazosin for Raynaud's phenomenon in progressive systemic sclerosis. ( Fenlon, D; Furst, D; Pope, J; Shea, B; Silman, A; Thompson, A; Wells, G, 2000) |
| "We suggest that Raynaud's disease is characterized by a defect in alpha 1-adrenoceptor function." | 1.28 | Adrenoceptors in Raynaud's disease. ( Bevegård, S; Ekenvall, L; Etzell, BM; Lindblad, LE, 1989) |
| "Nifedipine was shown to be effective in reducing both the frequency and the severity of Raynaud's phenomenon, whereas prazosin was ineffective." | 1.27 | Nifedipine and alpha 1-adrenergic blockade in Raynaud's phenomenon. ( Amor, B; Degeorges, M; Foult, JM; Kahan, A; Menkes, CJ; Weber, S, 1985) |
| "Among seven patients with Raynaud phenomenon, we have only a good result in one case (Buerger disease) and two cases with a little increase of the fingertips blood flow." | 1.26 | [Alpha blockers and microcirculation (author's transl)]. ( Cloarec, M; Dumas, JR; Graisely, B; Perdriset, G, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (71.43) | 18.7374 |
| 1990's | 5 (17.86) | 18.2507 |
| 2000's | 3 (10.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tagliarino, H | 1 |
| Purdon, M | 1 |
| Jamieson, B | 1 |
| Hoekzema, G | 1 |
| Bergstrom, KG | 1 |
| Perelman, RO | 1 |
| Cloarec, M | 1 |
| Graisely, B | 1 |
| Perdriset, G | 1 |
| Dumas, JR | 1 |
| Colucci, WS | 1 |
| Nielsen, SL | 1 |
| Vitting, K | 1 |
| Rasmussen, K | 1 |
| Pisenti, L | 1 |
| Hart, LL | 1 |
| Surwit, RS | 2 |
| Gilgor, RS | 2 |
| Allen, LM | 2 |
| Duvic, M | 2 |
| Giudice, PA | 1 |
| Freedman, RR | 1 |
| Baer, RP | 1 |
| Mayes, MD | 1 |
| Paterna, S | 1 |
| Pinto, A | 1 |
| Arrostuto, A | 1 |
| Cannavò, MG | 1 |
| Di Pasquale, P | 1 |
| Cottone, C | 1 |
| Licata, G | 1 |
| Cooke, JP | 1 |
| Creager, SJ | 1 |
| Scales, KM | 1 |
| Ren, C | 1 |
| Tsapatsaris, NP | 1 |
| Beetham, WP | 1 |
| Creager, MA | 1 |
| Pope, J | 1 |
| Fenlon, D | 1 |
| Thompson, A | 1 |
| Shea, B | 1 |
| Furst, D | 1 |
| Wells, G | 1 |
| Silman, A | 1 |
| Beaucher, WN | 1 |
| Coffman, JD | 1 |
| Appleby, BR | 1 |
| Waldo, R | 1 |
| Brouwer, RM | 2 |
| Wenting, GJ | 2 |
| Schalekamp, MA | 2 |
| Harker, CT | 1 |
| Ousley, PJ | 1 |
| Harris, EJ | 1 |
| Edwards, JM | 1 |
| Taylor, LM | 1 |
| Porter, JM | 1 |
| Lindblad, LE | 1 |
| Ekenvall, L | 1 |
| Etzell, BM | 1 |
| Bevegård, S | 1 |
| Wollersheim, H | 3 |
| Berden, J | 1 |
| Thien, T | 3 |
| vd Meiracker, AJ | 1 |
| Man in't Veld, AJ | 1 |
| Rochette, G | 1 |
| Bodolay, E | 1 |
| Hatvani, I | 1 |
| Szegedi, G | 1 |
| Fennis, J | 1 |
| van Elteren, P | 1 |
| van 't Laar, A | 1 |
| Russell, IJ | 1 |
| Lessard, JA | 1 |
| Kahan, A | 1 |
| Foult, JM | 1 |
| Weber, S | 1 |
| Amor, B | 1 |
| Menkes, CJ | 1 |
| Degeorges, M | 1 |
3 reviews available for prazosin and Cold Fingers, Hereditary
| Article | Year |
|---|---|
Clinical inquiries. What is the evaluation and treatment strategy for Raynaud's phenomenon?
Topics: Adrenergic alpha-Antagonists; Evidence-Based Medicine; Humans; Nifedipine; Practice Guidelines as To | 2005 |
Alpha-adrenergic receptor blockade with prazosin. Consideration of hypertension, heart failure, and potential new applications.
Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Child; Drug Tolerance; Heart Failure; H | 1982 |
Prazosin for Raynaud's phenomenon in progressive systemic sclerosis.
Topics: Adrenergic alpha-Antagonists; Humans; Prazosin; Raynaud Disease; Scleroderma, Systemic | 2000 |
9 trials available for prazosin and Cold Fingers, Hereditary
| Article | Year |
|---|---|
Prazosin treatment of primary Raynaud's phenomenon.
Topics: Blood Pressure; Clinical Trials as Topic; Cold Temperature; Double-Blind Method; Humans; Prazosin; P | 1983 |
DIAS rounds. Nifedipine and prazosin in Raynaud's phenomenon.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Nifedipine; Prazosin; Qu | 1984 |
A double-blind study of prazosin in the treatment of Raynaud's phenomenon in scleroderma.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Prazosin; Q | 1984 |
Blockade of vasospastic attacks by alpha 2-adrenergic but not alpha 1-adrenergic antagonists in idiopathic Raynaud's disease.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adult; Female; Hum | 1995 |
[Raynaud's phenomenon: effects of terazosin].
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Female; Humans; Male; Middle Aged; Prazosin; Raynaud Dise | 1997 |
Role of digital artery adrenoceptors in Raynaud's disease.
Topics: Adrenergic alpha-Antagonists; Adult; Arteries; Cold Temperature; Female; Fingers; Humans; Male; Plet | 1997 |
Dose-response study of prazosin in Raynaud's phenomenon: clinical effectiveness versus side effects.
Topics: Adolescent; Adult; Aged; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Female; Fing | 1988 |
Double-blind, placebo-controlled study of prazosin in Raynaud's phenomenon.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Drug Evaluation; Female; Fingers; Humans; Male; Middle | 1986 |
Prazosin treatment of Raynaud's phenomenon: a double blind single crossover study.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Fingers; Humans; | 1985 |
16 other studies available for prazosin and Cold Fingers, Hereditary
| Article | Year |
|---|---|
Treatment for Raynaud's: beyond calcium channel blockers.
Topics: Arginine; Bosentan; Botulinum Toxins; Calcium Channel Blockers; Humans; Piperazines; Prazosin; Purin | 2008 |
[Alpha blockers and microcirculation (author's transl)].
Topics: Adrenergic alpha-Antagonists; Humans; Hypertension; Microcirculation; Prazosin; Raynaud Disease | 1981 |
The combined effect of prazosin and autogenic training on cold reactivity in Raynaud's phenomenon.
Topics: Adult; Autogenic Training; Blood Pressure; Cold Temperature; Female; Fingers; Humans; Male; Middle A | 1982 |
[New views on therapy of Raynaud's syndrome. Preliminary note].
Topics: Adolescent; Adult; Drug Evaluation; Female; Humans; Male; Middle Aged; Prazosin; Quinazolines; Rayna | 1980 |
Vasodilator drugs for peripheral vascular disease.
Topics: Humans; Nitroglycerin; Ointments; Prazosin; Quinazolines; Raynaud Disease | 1979 |
Vasodilator drugs for peripheral vascular disease.
Topics: Griseofulvin; Humans; Nitroglycerin; Prazosin; Quinazolines; Raynaud Disease | 1979 |
Raynaud's phenomenon?
Topics: Aged; Female; Humans; Prazosin; Quinazolines; Raynaud Disease | 1978 |
Prazosin relieves Raynaud's vasospasm.
Topics: Adult; Amputation, Surgical; Blood Vessels; Female; Fingers; Humans; Muscle, Smooth; Prazosin; Quina | 1979 |
Acute effects and mechanism of action of ketanserin in patients with primary Raynaud's phenomenon.
Topics: Adult; Blood Gas Monitoring, Transcutaneous; Female; Fingers; Humans; Ketanserin; Lasers; Male; Oxyg | 1990 |
The effects of cooling on human saphenous vein reactivity to adrenergic agonists.
Topics: Cold Temperature; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle, Smooth, Vascular; | 1990 |
Adrenoceptors in Raynaud's disease.
Topics: Adult; Azepines; Doxazosin; Female; Fingers; Humans; Isoproterenol; Male; Middle Aged; Norepinephrin | 1989 |
Decreased rectal body temperature induced by different vasodilatory drugs.
Topics: Adult; Epoprostenol; Female; Humans; Hypertension; Hypothermia; Middle Aged; Nifedipine; Prazosin; R | 1989 |
Mechanism of action of ketanserin in hypertension and vasospastic disease.
Topics: Blood Pressure; Drug Therapy, Combination; Fingers; Humans; Hypertension; Ketanserin; Muscle, Smooth | 1987 |
[Action of prazosin on vasospasm in white finger disease].
Topics: Adult; Body Temperature; Cold Temperature; Fingers; Humans; Male; Prazosin; Raynaud Disease; Spasm; | 1988 |
Minipress treatment of primary Raynaud's disease.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prazosin; Raynaud Disease; Rese | 1986 |
Nifedipine and alpha 1-adrenergic blockade in Raynaud's phenomenon.
Topics: Adult; Blood Pressure; Double-Blind Method; Female; Humans; Male; Nifedipine; Phenylephrine; Prazosi | 1985 |