prazosin has been researched along with Cocaine Abuse in 7 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cocaine abuse and dependence are a global public health problem." | 3.85 | Synergistic interactions between mirtazapine and prazosin prevent the induction and expression of behavioral sensitization to cocaine in rats. ( Barbosa-Méndez, S; Matus-Ortega, M; Salazar-Juárez, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmidt, KT | 1 |
| Schroeder, JP | 1 |
| Foster, SL | 1 |
| Squires, K | 1 |
| Smith, BM | 1 |
| Pitts, EG | 1 |
| Epstein, MP | 1 |
| Weinshenker, D | 1 |
| Barbosa-Méndez, S | 1 |
| Matus-Ortega, M | 1 |
| Salazar-Juárez, A | 1 |
| Vanderschuren, LJ | 1 |
| Beemster, P | 1 |
| Schoffelmeer, AN | 1 |
| Zhang, XY | 1 |
| Kosten, TA | 1 |
| Tapp, AM | 1 |
| Kennedy, A | 1 |
| Peskind, ER | 1 |
| Raskind, MA | 1 |
| Platt, DM | 1 |
| Rowlett, JK | 1 |
| Spealman, RD | 1 |
| Wee, S | 1 |
| Mandyam, CD | 1 |
| Lekic, DM | 1 |
| Koob, GF | 1 |
7 other studies available for prazosin and Cocaine Abuse
| Article | Year |
|---|---|
Norepinephrine regulates cocaine-primed reinstatement via α1-adrenergic receptors in the medial prefrontal cortex.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Cocaine; Cocaine-Relate | 2017 |
Synergistic interactions between mirtazapine and prazosin prevent the induction and expression of behavioral sensitization to cocaine in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Anesthetics, Local; Animals; Cocaine; | 2017 |
On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Clonidine; Cocaine; Cocai | 2003 |
Prazosin, an alpha-1 adrenergic antagonist, reduces cocaine-induced reinstatement of drug-seeking.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cocaine; Cocaine-Rel | 2005 |
Beneficial effects of prazosin for visual hallucinations associated with chronic cocaine abuse.
Topics: Adrenergic alpha-Antagonists; Chronic Disease; Cocaine-Related Disorders; Crack Cocaine; Hallucinati | 2006 |
Noradrenergic mechanisms in cocaine-induced reinstatement of drug seeking in squirrel monkeys.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Addictive; Be | 2007 |
Alpha 1-noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Betax | 2008 |