prazosin has been researched along with Central Hypothyroidism in 15 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In hypothyroidism, 5'D-II is highly stimulated by the SNS and hypothyroxinemia." | 3.68 | Central role of brown adipose tissue thyroxine 5'-deiodinase on thyroid hormone-dependent thermogenic response to cold. ( Bianco, AC; Carvalho, SD; Kimura, ET; Silva, JE, 1991) |
| " The effect of artificial hypothyroidism (induced by feeding 6-propyl-2-thiouracil, PTU) and hyperthyroidism (induced by daily injections of triiodothyronine, T3) on myocardial adrenoceptor binding, catecholamines, some physiological responses, and their interdependence was examined." | 3.67 | Thyroid-dependent alterations of myocardial adrenoceptors and adrenoceptor-mediated responses in the rat. ( Gross, G; Lues, I, 1985) |
| "[3H]Prazosin binding was typical of an alpha 1-adrenergic receptor, and (-)epinephrine affinity for the [3H]prazosin-binding sites was not altered in the presence of 10(-5) M guanylyl-imidodiphosphate." | 1.27 | Normal ontogeny of alpha 1-adrenergic receptor in rat liver is thyroid hormone dependent. ( Noguchi, A, 1983) |
| "Prazosin (1 microM) was used to define nonspecific binding of [3H]DHE." | 1.27 | Alpha 1-adrenoreceptors and alpha 1-adrenoreceptor-mediated thyrotropin release in cultures of euthyroid and hypothyroid rat anterior pituitary cells. ( Dieguez, C; Foord, SM; Hall, R; Peters, JR; Scanlon, MF, 1985) |
| "Acquired hypothyroidism is also associated with a decreased density of alpha 1- and beta-adrenergic receptors in rat myocardium." | 1.26 | Ontogeny of alpha 1-adrenergic receptors in the rat myocardium: effects of hypothyroidism. ( Noguchi, A; Whitsett, JA, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zaninovich, AA | 1 |
| Rebagliati, I | 1 |
| Raices, M | 1 |
| Ricci, C | 1 |
| Hagmuller, K | 1 |
| Yasuzawa-Amano, S | 1 |
| Toyoda, N | 1 |
| Maeda, A | 1 |
| Kosaki, A | 1 |
| Mori, Y | 1 |
| Iwasaka, T | 1 |
| Nishikawa, M | 1 |
| Medina, JH | 1 |
| Wolfman, C | 1 |
| Levi de Stein, M | 1 |
| Tumilasci, O | 1 |
| Houssay, AB | 1 |
| Chang, HY | 1 |
| Kunos, G | 2 |
| Preiksaitis, HG | 1 |
| Kan, WH | 1 |
| Noguchi, A | 2 |
| Whitsett, JA | 1 |
| Corvera, S | 1 |
| García-Sáinz, JA | 1 |
| Oguro, K | 1 |
| Ohguchi, S | 1 |
| Nakashima, M | 1 |
| Sandrini, M | 1 |
| Marrama, D | 1 |
| Vergoni, AV | 1 |
| Bertolini, A | 1 |
| Carvalho, SD | 1 |
| Kimura, ET | 1 |
| Bianco, AC | 1 |
| Silva, JE | 2 |
| Mills, I | 1 |
| Raasmaja, A | 1 |
| Moolten, N | 1 |
| Lemack, G | 1 |
| Larsen, PR | 1 |
| Dieguez, C | 1 |
| Foord, SM | 1 |
| Peters, JR | 1 |
| Hall, R | 1 |
| Scanlon, MF | 1 |
| Storm, H | 1 |
| van Hardeveld, C | 1 |
| Gross, G | 1 |
| Lues, I | 1 |
15 other studies available for prazosin and Central Hypothyroidism
| Article | Year |
|---|---|
Mitochondrial respiration in muscle and liver from cold-acclimated hypothyroid rats.
Topics: Adipose Tissue, Brown; Adrenergic Antagonists; Adrenergic Uptake Inhibitors; Animals; Body Weight; C | 2003 |
Expression and regulation of type 2 iodothyronine deiodinase in rat aorta media.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aorta; Gene Expression Regulatio | 2004 |
Thyroid hormone regulation of adrenergic receptors and beta-adrenergic responsiveness in the rat submandibular gland.
Topics: Animals; Dihydroalprenolol; Hyperthyroidism; Hypothyroidism; Isoproterenol; Kinetics; Male; Prazosin | 1984 |
Short term effects of triiodothyronine on rat heart adrenoceptors.
Topics: Animals; Dihydroalprenolol; Hypothyroidism; Kinetics; Male; Myocardium; Prazosin; Rats; Receptors, A | 1981 |
Decreased alpha 1-adrenoceptor responsiveness and density in liver cells of thyroidectomized rats.
Topics: Animals; Binding, Competitive; Calcium; Enzyme Activation; Epinephrine; Hypothyroidism; In Vitro Tec | 1982 |
Ontogeny of alpha 1-adrenergic receptors in the rat myocardium: effects of hypothyroidism.
Topics: Animals; Animals, Newborn; Congenital Hypothyroidism; Dihydroalprenolol; Heart; Hypothyroidism; Kine | 1982 |
Normal ontogeny of alpha 1-adrenergic receptor in rat liver is thyroid hormone dependent.
Topics: Aging; Animals; Binding, Competitive; Cell Membrane; Female; Hypothyroidism; Kinetics; Liver; Male; | 1983 |
Hypothyroidism abolishes the glycogenolytic effect of vasopressin, angiotensin II and A23187 but not that of alpha 1-adrenergic amines in rat hepatocytes.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Calcimycin; Epinephrine; Female; Hypothyroidism; Kine | 1983 |
Induction of opposite response of hindlimb vasculature to adrenergic agents in hypothyroid rats.
Topics: Acetylcholine; Animals; Blood Pressure; Clonidine; Heart Rate; Hindlimb; Hypothyroidism; In Vitro Te | 1984 |
Effects of thyroid status on the characteristics of alpha 1-, alpha 2-, beta, imipramine and GABA receptors in the rat brain.
Topics: Animals; Brain; Dihydroalprenolol; Hyperthyroidism; Hypothyroidism; Imipramine; Kinetics; Male; Musc | 1991 |
Central role of brown adipose tissue thyroxine 5'-deiodinase on thyroid hormone-dependent thermogenic response to cold.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Calorimetry; Cell Nucleus; Cold Tempera | 1991 |
Effect of thyroid status on catecholamine stimulation of thyroxine 5'-deiodinase in brown adipocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue, Brown; Alprenolol; Animals; Catecholamines; | 1989 |
Alpha 1-adrenoreceptors and alpha 1-adrenoreceptor-mediated thyrotropin release in cultures of euthyroid and hypothyroid rat anterior pituitary cells.
Topics: Animals; Calcimycin; Cells, Cultured; Epinephrine; Hypothyroidism; Isoproterenol; Kinetics; Male; Pi | 1985 |
Effect of hypothyroidism on the cytosolic free Ca2+ concentration in rat hepatocytes during rest and following stimulation by noradrenaline or vasopressin.
Topics: Animals; Calcium; Cytosol; Hypothyroidism; Liver; Male; Norepinephrine; Oxygen Consumption; Prazosin | 1986 |
Thyroid-dependent alterations of myocardial adrenoceptors and adrenoceptor-mediated responses in the rat.
Topics: Animals; Cycloheximide; Decerebrate State; Dihydroalprenolol; Dose-Response Relationship, Drug; Elec | 1985 |