prazosin has been researched along with Catatonic Rigidity in 4 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This implied muscular rigidity was appreciably antagonized by prior intrathecal (10 microliters) administration of prazosin (5 or 10 nmol), but not equimolar dose of yohimbine." | 1.29 | Inhibition by intrathecal prazosin but not yohimbine of fentanyl-induced muscular rigidity in the rat. ( Chan, SH; Fu, MJ; Lee, TY; Lui, PW; Tsen, LY; Yeh, CP, 1995) |
| "This correlate of opiate-induced muscular rigidity was appreciably antagonized by a pretreatment with the specific alpha 1-adrenoceptor blocker, prazosin (250 micrograms/kg, i." | 1.28 | Involvement of coerulospinal noradrenergic pathway in fentanyl-induced muscular rigidity in rats. ( Chan, SH; Lee, TY; Lui, PW, 1990) |
| "Whereas muscular rigidity is a well-known phenomenon that is related to anesthesia induced by large doses of narcotic drugs, the precise underlying mechanism(s) remain to be fully elucidated." | 1.28 | Differential effects of prazosin and yohimbine on fentanyl-induced muscular rigidity in rats. ( Chan, SH; Lee, TY; Lui, PW; Pan, JT; Tsou, MY, 1989) |
| "Whereas muscular rigidity is a well-known side effect that is associated with high-dose fentanyl anesthesia, a paucity of information exists with regard to its underlying mechanism(s)." | 1.28 | Involvement of locus coeruleus and noradrenergic neurotransmission in fentanyl-induced muscular rigidity in the rat. ( Chan, SH; Lee, TY; Lui, PW, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lui, PW | 4 |
| Tsen, LY | 1 |
| Fu, MJ | 1 |
| Yeh, CP | 1 |
| Lee, TY | 4 |
| Chan, SH | 4 |
| Tsou, MY | 1 |
| Pan, JT | 1 |
4 other studies available for prazosin and Catatonic Rigidity
| Article | Year |
|---|---|
Inhibition by intrathecal prazosin but not yohimbine of fentanyl-induced muscular rigidity in the rat.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Electromyography; Fentanyl; Injections, I | 1995 |
Involvement of coerulospinal noradrenergic pathway in fentanyl-induced muscular rigidity in rats.
Topics: Adrenergic Fibers; Animals; Dose-Response Relationship, Drug; Fentanyl; Locus Coeruleus; Male; Micro | 1990 |
Differential effects of prazosin and yohimbine on fentanyl-induced muscular rigidity in rats.
Topics: Animals; Blood Pressure; Electromyography; Fentanyl; Heart Rate; Male; Muscle Rigidity; Muscles; Pra | 1989 |
Involvement of locus coeruleus and noradrenergic neurotransmission in fentanyl-induced muscular rigidity in the rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Anesthetics; Animals; Dose-Response Relationship, D | 1989 |