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prazosin and Catatonic Rigidity

prazosin has been researched along with Catatonic Rigidity in 4 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"This implied muscular rigidity was appreciably antagonized by prior intrathecal (10 microliters) administration of prazosin (5 or 10 nmol), but not equimolar dose of yohimbine."1.29Inhibition by intrathecal prazosin but not yohimbine of fentanyl-induced muscular rigidity in the rat. ( Chan, SH; Fu, MJ; Lee, TY; Lui, PW; Tsen, LY; Yeh, CP, 1995)
"This correlate of opiate-induced muscular rigidity was appreciably antagonized by a pretreatment with the specific alpha 1-adrenoceptor blocker, prazosin (250 micrograms/kg, i."1.28Involvement of coerulospinal noradrenergic pathway in fentanyl-induced muscular rigidity in rats. ( Chan, SH; Lee, TY; Lui, PW, 1990)
"Whereas muscular rigidity is a well-known phenomenon that is related to anesthesia induced by large doses of narcotic drugs, the precise underlying mechanism(s) remain to be fully elucidated."1.28Differential effects of prazosin and yohimbine on fentanyl-induced muscular rigidity in rats. ( Chan, SH; Lee, TY; Lui, PW; Pan, JT; Tsou, MY, 1989)
"Whereas muscular rigidity is a well-known side effect that is associated with high-dose fentanyl anesthesia, a paucity of information exists with regard to its underlying mechanism(s)."1.28Involvement of locus coeruleus and noradrenergic neurotransmission in fentanyl-induced muscular rigidity in the rat. ( Chan, SH; Lee, TY; Lui, PW, 1989)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lui, PW4
Tsen, LY1
Fu, MJ1
Yeh, CP1
Lee, TY4
Chan, SH4
Tsou, MY1
Pan, JT1

Other Studies

4 other studies available for prazosin and Catatonic Rigidity

ArticleYear
Inhibition by intrathecal prazosin but not yohimbine of fentanyl-induced muscular rigidity in the rat.
    Neuroscience letters, 1995, Dec-08, Volume: 201, Issue:2

    Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Electromyography; Fentanyl; Injections, I

1995
Involvement of coerulospinal noradrenergic pathway in fentanyl-induced muscular rigidity in rats.
    Neuroscience letters, 1990, Jan-01, Volume: 108, Issue:1-2

    Topics: Adrenergic Fibers; Animals; Dose-Response Relationship, Drug; Fentanyl; Locus Coeruleus; Male; Micro

1990
Differential effects of prazosin and yohimbine on fentanyl-induced muscular rigidity in rats.
    Neuropharmacology, 1989, Volume: 28, Issue:11

    Topics: Animals; Blood Pressure; Electromyography; Fentanyl; Heart Rate; Male; Muscle Rigidity; Muscles; Pra

1989
Involvement of locus coeruleus and noradrenergic neurotransmission in fentanyl-induced muscular rigidity in the rat.
    Neuroscience letters, 1989, Jan-02, Volume: 96, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Anesthetics; Animals; Dose-Response Relationship, D

1989