Page last updated: 2024-11-03

prazosin and Cardiovascular Stroke

prazosin has been researched along with Cardiovascular Stroke in 55 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"We describe a 71-year-old male patient who developed acute myocardial infarction (AMI) due to a dynamic left ventricular outflow tract obstruction induced by terazosin."7.83Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report. ( Ferrando-Castagnetto, F; Lluberas, N; Martínez, F; Vidal Margenat, A; Vignolo, G, 2016)
"Central hemodynamic parameters were monitored by invasive procedures (pulmonary arterial catheterization), and prazosin kinetics following the administration of a single 5 mg dose were determined in 69 patients with subacute myocardial infarction, complicated by heart failure."7.67[Prazosin pharmacodynamics and pharmacokinetics in patients with myocardial infarct complicated by heart failure in the subacute period]. ( Gofman, AM; Ol'binskaia, LI; Petrosian, IuR, 1987)
"Prazosine and isosorbide dinitrate have been studied in 15 patients with acute myocardial infarction complicated by heart failure."7.66Peripheral resistances in acute myocardial infarction: the use of prazosine versus isosorbide dinitrate. ( Costa, PP; Croce, G; Fernandes, P; Permutti, B, 1980)
"The hemodynamic effects of the new oral vasocilator prazosin were evaluated in 11 patients with congestive failure following myocardial infarction."7.66Use of oral prazosin hydrochloride in congestive failure following acute myocardial infarction. ( Coma-Canella, I; Jadraque, LM; Lombera, F; Lopez-Sendon, J, 1979)
"To elucidate the hemodynamic effects of prazosin, an antihypertensive agent, in congestive heart failure, we studied 10 patients with ischemic cardiomyopathy and severe ventricular dysfunction."7.65Sustained reduction of cardiac impedance and preload in congestive heart failure with the antihypertensive vasodilator prazosin. ( Awan, NA; Mason, DT; Maxwell, KS; Miller, RR, 1977)
"We describe a 71-year-old male patient who developed acute myocardial infarction (AMI) due to a dynamic left ventricular outflow tract obstruction induced by terazosin."3.83Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report. ( Ferrando-Castagnetto, F; Lluberas, N; Martínez, F; Vidal Margenat, A; Vignolo, G, 2016)
"The present study sought to evaluate the effects of the afterload-reducing drugs captopril and prazosin on changes in antioxidants as well as oxidative stress in relation to hemodynamic function in congestive heart failure (CHF) subsequent to myocardial infarction (MI)."3.69Effects of afterload-reducing drugs on pathogenesis of antioxidant changes and congestive heart failure in rats. ( Khaper, N; Singal, PK, 1997)
"[3H]Prazosin binding was determined in arterial segments of Wistar-Kyoto rats (WKY), and of Wistar rats 5 weeks after myocardial infarction (MI) or sham operation (SHAM)."3.69Alpha 1-adrenoceptor subtypes in rat aorta and mesenteric small arteries are preserved during left ventricular dysfunction post-myocardial infarction. ( DeMey, JG; Janssen, GM; Stassen, FR; Willemsen, MJ, 1997)
"The effect of alpha 1-adrenergic blockade with prazosin on myocardial blood flow at rest and during two levels of treadmill exercise was assessed in 16 chronically instrumented dogs 9-14 days after myocardial infarction had been produced by occlusion of the left circumflex coronary artery."3.68Effect of alpha 1-adrenergic blockade on myocardial blood flow during exercise after myocardial infarction. ( Bache, RJ; Dai, XZ; Herzog, CA, 1991)
"The antiarrhythmic and antifibrillatory actions of the alpha 1-adrenoceptor antagonist prazosin were evaluated in conscious dogs 4-7 days after anterior myocardial infarction."3.67Alpha-adrenergic influences in canine ischemic sudden death: effects of alpha 1-adrenoceptor blockade with prazosin. ( Lucchesi, BR; Lynch, JJ; Montgomery, DG; Wilber, DJ, 1987)
"Central hemodynamic parameters were monitored by invasive procedures (pulmonary arterial catheterization), and prazosin kinetics following the administration of a single 5 mg dose were determined in 69 patients with subacute myocardial infarction, complicated by heart failure."3.67[Prazosin pharmacodynamics and pharmacokinetics in patients with myocardial infarct complicated by heart failure in the subacute period]. ( Gofman, AM; Ol'binskaia, LI; Petrosian, IuR, 1987)
"To investigate the possibility of limiting infarct size by decreasing afterload 32 normotensive patients with uncomplicated acute myocardial infarction (AMI) were put on prazosin and compared with 32 control patients."3.66Limitation of infarct size by decrease of afterload with prazosin. ( Alexandris, AT; Kalogeropoulos, CK; Karlas, EN; Kolettis, MT; Tzannetis, GC, 1983)
"Prazosine and isosorbide dinitrate have been studied in 15 patients with acute myocardial infarction complicated by heart failure."3.66Peripheral resistances in acute myocardial infarction: the use of prazosine versus isosorbide dinitrate. ( Costa, PP; Croce, G; Fernandes, P; Permutti, B, 1980)
"The hemodynamic effects of the new oral vasocilator prazosin were evaluated in 11 patients with congestive failure following myocardial infarction."3.66Use of oral prazosin hydrochloride in congestive failure following acute myocardial infarction. ( Coma-Canella, I; Jadraque, LM; Lombera, F; Lopez-Sendon, J, 1979)
"To elucidate the hemodynamic effects of prazosin, an antihypertensive agent, in congestive heart failure, we studied 10 patients with ischemic cardiomyopathy and severe ventricular dysfunction."3.65Sustained reduction of cardiac impedance and preload in congestive heart failure with the antihypertensive vasodilator prazosin. ( Awan, NA; Mason, DT; Maxwell, KS; Miller, RR, 1977)
"Treatment with prazosin for one month also reduced systemic vascular resistance by 8%, renal vascular resistance increased by 20%, and renal blood flow and the percentage of the cardiac output going to the kidney fell by 14% and 26%."2.66The renal response to neuroendocrine inhibition in chronic heart failure: double-blind comparison of captopril and prazosin. ( Bayliss, J; Canepa-Anson, R; Norell, M; Poole-Wilson, P; Sutton, G, 1986)
"Incidences and severity of ventricular arrhythmia during ischemia and early reperfusion significantly decreased in noradrenaline preconditioned group compared with saline-control group."1.37Noradrenaline protects in vivo rat heart against infarction and ventricular arrhythmias via nitric oxide and reactive oxygen species. ( Alizadeh, AM; Faghihi, M; Imani, A; Niaraki, SS; Sadr, SS, 2011)
"Reserpine pretreatment attenuated this protective effect of preconditioning on reperfusion-induced arrhythmias."1.30The possible role of adrenergic component in ischemic preconditioning. ( Sharma, A; Singh, M, 1997)
"Tyramine pretreatment resulted in a smaller infarct size than in untreated controls (AN/AR, 0."1.29Alpha-adrenoceptor stimulation with exogenous norepinephrine or release of endogenous catecholamines mimics ischemic preconditioning. ( Bankwala, Z; Hale, SL; Kloner, RA, 1994)
"Adenosine receptors were blocked with 8-p-sulfophenyl theophylline (10 mg/kg intravenously), alpha 1-adrenergic receptors were selectively blocked with prazosin (0."1.29Adrenergic activation confers cardioprotection mediated by adenosine, but is not required for ischemic preconditioning. ( Chien, GL; Davis, RF; Haessler, R; Kuzume, K; Van Winkle, DM; Wolff, RA, 1996)
"In phentolamine-treated dogs, arterial pressure and heart rate were kept constant to prevent exacerbation of ischemia."1.27Effect of alpha-adrenergic blockade on arrhythmias induced by acute myocardial ischemia and reperfusion in the dog. ( Bolli, R; Fisher, DJ; Miller, RR; Taylor, AA; Young, JB, 1984)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199031 (56.36)18.7374
1990's17 (30.91)18.2507
2000's2 (3.64)29.6817
2010's5 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wahab, NA1
Zainudin, S1
AbAziz, A1
Kamaruddin, NA1
Nunez, WR1
Ozaki, MR1
Vinagre, AM1
Collares, EF1
Almeida, EA1
Lamont, K1
Nduhirabandi, F1
Adam, T1
Thomas, DP1
Opie, LH2
Lecour, S1
Vidal Margenat, A1
Ferrando-Castagnetto, F1
Martínez, F1
Lluberas, N1
Vignolo, G1
Imani, A1
Faghihi, M1
Sadr, SS1
Niaraki, SS1
Alizadeh, AM1
Fu, YJ1
Shu, H1
Miao, CY1
Wang, MW1
Su, DF1
Bolli, R1
Fisher, DJ1
Taylor, AA1
Young, JB1
Miller, RR3
Chatterjee, K2
Parmley, WW2
Manno, BV1
Iskandrian, AS1
Hakki, AH1
Kolettis, MT1
Karlas, EN1
Tzannetis, GC1
Kalogeropoulos, CK1
Alexandris, AT1
Kather, H1
Colucci, WS1
Wynne, J1
Holman, BL1
Braunwald, E1
Khomenko, VL1
Pomerantsev, VP1
Vasiuk, IuA1
Wagner, GC1
Robinson, PH1
Seino, Y1
Takano, T1
Endo, T1
Obayashi, K1
Hayakawa, H1
Vyden, JK1
Rose, HB1
Kimura, E1
Tzivoni, D1
Keren, A1
Benhorin, J1
Gottlieb, S1
Atlas, D1
Stern, S1
Storm-Mathisen, H1
Løken, H1
Hebnes, K1
Rouleau, JL1
Benge, W1
Hiramatsu, B1
Engler, R1
Pouleur, H1
Link, J1
Printz, M1
Covell, JW1
López-Sendón, J2
Coma Canella, I1
Trongé, J1
Villamayor, RM1
Pérez Baliño, N1
Riccitelli, MA1
Bertolasi, CA2
Oliveri, R1
Cremades, E1
Bazzino, O1
Doval, H1
Mason, DT4
Costa, PP1
Permutti, B1
Fernandes, P1
Croce, G1
Billman, GE1
Bankwala, Z1
Hale, SL1
Kloner, RA1
Kitakaze, M1
Hori, M1
Morioka, T1
Minamino, T1
Takashima, S1
Sato, H1
Shinozaki, Y1
Chujo, M1
Mori, H1
Inoue, M1
Saeki, K1
Ogawa, S1
Sadanaga, T1
Yoh, S1
Furuno, I1
Nakamura, Y1
Haessler, R1
Kuzume, K2
Wolff, RA1
Chien, GL1
Davis, RF1
Van Winkle, DM1
Khaper, N1
Singal, PK1
Stassen, FR1
Willemsen, MJ1
Janssen, GM1
DeMey, JG1
Sharma, A2
Singh, M2
Fujita, M1
Tanaka, T1
Nakae, I1
Tamaki, S1
Kihara, Y1
Nohara, R1
Sasayama, S1
Lloyd, EA1
Awan, NA2
Coma-Canella, I1
Lombera, F1
Jadraque, LM1
Maxwell, KS1
Verma, SP1
Silke, B1
Reynolds, GW1
Kelly, JG1
Richmond, A1
Taylor, SH1
Boutjdir, M1
el-Sherif, N1
Herzog, CA1
Dai, XZ1
Bache, RJ1
Rowley, KG1
Tung, LH1
Hodsman, GP1
Howes, LG1
Jarrott, B1
Beart, PM1
Louis, WJ1
Murdock, CJ1
Hickey, GM1
Hockings, BE1
Pitman, GF1
Taylor, RR1
Morozova, TE2
Petrosian, IuR2
Gofman, AM2
Itaya, T1
Hashimoto, H1
Satoh, R1
Uematsu, T1
Nakashima, M1
Wilber, DJ1
Lynch, JJ1
Montgomery, DG1
Lucchesi, BR1
Franciosa, JA1
Ol'binskaia, LI2
Wood, M1
Bayliss, J1
Canepa-Anson, R1
Norell, M1
Poole-Wilson, P1
Sutton, G1

Reviews

6 reviews available for prazosin and Cardiovascular Stroke

ArticleYear
Right ventricular function: methodologic and clinical considerations in noninvasive scintigraphic assessment.
    Journal of the American College of Cardiology, 1984, Volume: 3, Issue:4

    Topics: Animals; Captopril; Coronary Disease; Echocardiography; Heart; Heart Defects, Congenital; Heart Vent

1984
[Peripheral vasodilator agents in cardiology].
    Sovetskaia meditsina, 1980, Issue:12

    Topics: Clinical Trials as Topic; Coronary Vessels; Heart Failure; Hemodynamics; Humans; Hydralazine; Myocar

1980
Afterload reduction and cardiac performance. Physiologic basis of systemic vasodilators as a new approach in treatment of congestive heart failure.
    The American journal of medicine, 1978, Volume: 65, Issue:1

    Topics: Aorta; Cardiac Output; Chronic Disease; Heart; Heart Failure; Heart Ventricles; Hemodynamics; Humans

1978
The use of vasodilator agents in the treatment of heart failure.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Nov-10, Volume: 56, Issue:20

    Topics: Cardiac Output; Cardiomegaly; Catheterization; Chronic Disease; Coronary Vessels; Dose-Response Rela

1979
Afterload reduction in the management of congestive heart failure following acute myocardial infarction.
    Advances in cardiology, 1978, Volume: 23

    Topics: Acute Disease; Dopamine; Heart Failure; Hemodynamics; Humans; Hydralazine; Myocardial Infarction; Ni

1978
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca

1986

Trials

5 trials available for prazosin and Cardiovascular Stroke

ArticleYear
Long-term therapy of heart failure with prazosin: a randomized double blind trial.
    The American journal of cardiology, 1980, Volume: 45, Issue:2

    Topics: Adult; Aged; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Drug Toleranc

1980
[Peripheral vasodilator agents in cardiology].
    Sovetskaia meditsina, 1980, Issue:12

    Topics: Clinical Trials as Topic; Coronary Vessels; Heart Failure; Hemodynamics; Humans; Hydralazine; Myocar

1980
Alterations in left ventricular function and coronary hemodynamics with captopril, hydralazine and prazosin in chronic ischemic heart failure: a comparative study.
    Circulation, 1982, Volume: 65, Issue:4

    Topics: Aged; Captopril; Coronary Disease; Dose-Response Relationship, Drug; Heart Failure; Hemodynamics; Hu

1982
Effect of alpha 1-adrenoceptor blockade on ventricular ectopic beats inacute myocardial infarction.
    International journal of cardiology, 1990, Volume: 26, Issue:1

    Topics: Adrenergic alpha-Antagonists; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Myocardia

1990
The renal response to neuroendocrine inhibition in chronic heart failure: double-blind comparison of captopril and prazosin.
    European heart journal, 1986, Volume: 7, Issue:10

    Topics: Aged; Aldosterone; Captopril; Cardiac Output; Cardiomyopathy, Dilated; Coronary Disease; Double-Blin

1986

Other Studies

45 other studies available for prazosin and Cardiovascular Stroke

ArticleYear
Utility of alpha-blockade in a hypotensive pheochromocytoma patient with myocardial infarction.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2015, Volume: 24, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-1 Receptor Antagonists; Adult; Echocardiography; Humans; H

2015
Neural mechanisms and delayed gastric emptying of liquid induced through acute myocardial infarction in rats.
    Arquivos brasileiros de cardiologia, 2015, Volume: 104, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Baclofen; GABA-B Receptor Agonists; Gastric Emptyi

2015
Role of melatonin, melatonin receptors and STAT3 in the cardioprotective effect of chronic and moderate consumption of red wine.
    Biochemical and biophysical research communications, 2015, Oct-02, Volume: 465, Issue:4

    Topics: Animals; Cardiotonic Agents; Male; Melatonin; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial I

2015
Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report.
    Medwave, 2016, Jun-28, Volume: 16, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Angina Pectoris; Cardiomyopathies; Coronary Angiograp

2016
Noradrenaline protects in vivo rat heart against infarction and ventricular arrhythmias via nitric oxide and reactive oxygen species.
    The Journal of surgical research, 2011, Volume: 169, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Arrhythmias, Cardiac; Cyclic N-Oxides; Ischemic Preconditioning,

2011
Restoration of baroreflex function by ketanserin is not blood pressure dependent in conscious freely moving rats.
    Journal of hypertension, 2004, Volume: 22, Issue:6

    Topics: Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Female; Ketanserin; Male; Myocardial I

2004
Calcium ions, drug action and the heart--with special reference to calcium antagonist drugs.
    Pharmacology & therapeutics, 1984, Volume: 25, Issue:3

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channe

1984
Effect of alpha-adrenergic blockade on arrhythmias induced by acute myocardial ischemia and reperfusion in the dog.
    Journal of molecular and cellular cardiology, 1984, Volume: 16, Issue:12

    Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Coronar

1984
Vasodilator therapy for acute myocardial infarction and chronic congestive heart failure.
    Journal of the American College of Cardiology, 1983, Volume: 1, Issue:1

    Topics: Captopril; Heart Failure; Hemodynamics; Humans; Hydralazine; Myocardial Infarction; Prazosin; Region

1983
Limitation of infarct size by decrease of afterload with prazosin.
    Acta cardiologica, 1983, Volume: 38, Issue:5

    Topics: Adult; Aged; Aspartate Aminotransferases; Electrocardiography; Female; Hemodynamics; Humans; L-Lacta

1983
[Hypertensive therapy with prazosin. Concomitant cardiovascular, metabolic and respiratory diseases. Proven facts and potential aspects].
    Fortschritte der Medizin, 1984, Apr-26, Volume: 102, Issue:16

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Cardiovascular Diseases; Diabetes Complications; Humans; Hy

1984
The role of vasodilator therapy in the management of the patient with acute myocardial infarction.
    Primary care, 1981, Volume: 8, Issue:3

    Topics: Heart Failure; Heart Rupture; Hemodynamics; Humans; Hydralazine; Mitral Valve Insufficiency; Myocard

1981
Unloading effects of vasodilators on peripheral circulation and cardiac hemodynamics in patients with acute myocardial infarction.
    Japanese heart journal, 1982, Volume: 23, Issue:6

    Topics: Adult; Aged; Female; Heart; Hemodynamics; Humans; Isosorbide Dinitrate; Leg; Male; Middle Aged; Myoc

1982
Prazosin therapy for refractory variant angina.
    American heart journal, 1983, Volume: 105, Issue:2

    Topics: Aged; Angina Pectoris, Variant; Coronary Vasospasm; Electrocardiography; Female; Humans; Male; Middl

1983
Complications in long term treatment of essential hypertension.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 646

    Topics: Benzothiadiazines; Diuretics; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Myocardia

1981
Changes in control of renin release in congestive heart failure in dogs: response to acute and chronic vasodilator therapy.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:4-5

    Topics: Animals; Blood Pressure; Blood Volume; Dogs; Heart Failure; Heart Rate; Hydralazine; Myocardial Infa

1982
[Comparative hemodynamic effect of sodium nitroprusside and prazosin hydrochloride in patients with cardiac insufficiency following acute myocardial infarction].
    Revista espanola de cardiologia, 1981, Volume: 34, Issue:1

    Topics: Aged; Female; Ferricyanides; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infa

1981
[Vasodilator therapy of pump failure in acute myocardial infarction].
    Cardiology, 1980, Volume: 66 Suppl 2

    Topics: Adult; Aged; Female; Ferricyanides; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male;

1980
[Acute myocardial infarction with pump failure: hemodynamic response to prazosin].
    Cardiology, 1980, Volume: 66 Suppl 2

    Topics: Adult; Aged; Arterioles; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardial

1980
Vasodilator therapy in congestive heart failure.
    Annals of the Academy of Medicine, Singapore, 1981, Volume: 10, Issue:4 Suppl

    Topics: Heart Failure; Hemodynamics; Humans; Myocardial Infarction; Prazosin; Quinazolines; Vasodilator Agen

1981
Peripheral resistances in acute myocardial infarction: the use of prazosine versus isosorbide dinitrate.
    International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:5

    Topics: Cardiac Output; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardial Infarction; Prazosin; Quinazo

1980
Effect of alpha 1-adrenergic receptor antagonists on susceptibility to malignant arrhythmias: protection from ventricular fibrillation.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dioxanes; Disease Models, Animal; Dogs; Elect

1994
Alpha-adrenoceptor stimulation with exogenous norepinephrine or release of endogenous catecholamines mimics ischemic preconditioning.
    Circulation, 1994, Volume: 90, Issue:2

    Topics: Animals; Blood Pressure; Coronary Circulation; Heart Rate; Male; Myocardial Infarction; Myocardial I

1994
Alpha 1-adrenoceptor activation mediates the infarct size-limiting effect of ischemic preconditioning through augmentation of 5'-nucleotidase activity.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:5

    Topics: 5'-Nucleotidase; Adaptation, Biological; Adenosine; Animals; Blood Pressure; Dogs; Endocardium; Esop

1994
Sympathetic denervation of the epicardial border zone in the genesis of dispersion of refractoriness and arrhythmogenesis in a 7-day-old canine myocardial infarction model.
    Coronary artery disease, 1993, Volume: 4, Issue:9

    Topics: Animals; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Models, Biological; Myocardial Infarction

1993
Adrenergic activation confers cardioprotection mediated by adenosine, but is not required for ischemic preconditioning.
    Coronary artery disease, 1996, Volume: 7, Issue:4

    Topics: Adenosine; Adrenergic alpha-Agonists; Animals; Ischemic Preconditioning, Myocardial; Myocardial Infa

1996
Effects of afterload-reducing drugs on pathogenesis of antioxidant changes and congestive heart failure in rats.
    Journal of the American College of Cardiology, 1997, Mar-15, Volume: 29, Issue:4

    Topics: Animals; Captopril; Catalase; Glutathione Peroxidase; Heart; Heart Failure; Hemodynamics; Lipid Pero

1997
Alpha 1-adrenoceptor subtypes in rat aorta and mesenteric small arteries are preserved during left ventricular dysfunction post-myocardial infarction.
    Cardiovascular research, 1997, Volume: 33, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Calcium Channel Blockers; Dihydropyridines; In Vitro T

1997
The possible role of adrenergic component in ischemic preconditioning.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:7

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Blood Pressure; Catecholamines;

1997
Importance of alpha 1-sympathetic activity for diurnal change in ischemic threshold in patients with stable angina.
    Clinical cardiology, 1998, Volume: 21, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Amlodipine; Analysis of Variance; Angina Pectoris; Calciu

1998
Possible mechanism of cardioprotective effect of ischaemic preconditioning in isolated rat heart.
    Pharmacological research, 2000, Volume: 41, Issue:6

    Topics: Animals; Colchicine; Creatine Kinase; Female; In Vitro Techniques; Ischemic Preconditioning, Myocard

2000
Use of oral prazosin hydrochloride in congestive failure following acute myocardial infarction.
    American heart journal, 1979, Volume: 98, Issue:4

    Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Female; Heart Failure; Heart Rate; Humans; Male

1979
Vasodilator and inotropic therapy of heart failure [panel discussion].
    The American journal of medicine, 1978, Volume: 65, Issue:1

    Topics: Animals; Cardiac Output; Coronary Circulation; Dobutamine; Dogs; Dose-Response Relationship, Drug; H

1978
Sustained reduction of cardiac impedance and preload in congestive heart failure with the antihypertensive vasodilator prazosin.
    The New England journal of medicine, 1977, Aug-11, Volume: 297, Issue:6

    Topics: Blood Pressure; Cardiac Output; Female; Heart; Heart Failure; Heart Rate; Hemodynamics; Humans; Male

1977
Vasodilator therapy for acute heart failure: haemodynamic comparison of hydralazine/isosorbide, alpha-adrenoceptor blockade, and angiotensin-converting enzyme inhibition.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cardiac Output,

1992
Alpha 1-adrenoceptor regulation of delayed afterdepolarizations and triggered activity in subendocardial Purkinje fibers surviving 1 day of myocardial infarction.
    Journal of molecular and cellular cardiology, 1991, Volume: 23, Issue:1

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Dogs; Heart; Myocardial Infarction; Myocardium

1991
Effect of alpha 1-adrenergic blockade on myocardial blood flow during exercise after myocardial infarction.
    The American journal of physiology, 1991, Volume: 261, Issue:2 Pt 2

    Topics: Adrenergic alpha-Antagonists; Animals; Coronary Circulation; Dogs; Female; Hemodynamics; Male; Motor

1991
Altered alpha 1-adrenoceptor-mediated responses in atria of rats with chronic left ventricular infarction.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:3

    Topics: Animals; Chronic Disease; Female; Heart; Heart Rate; Inositol Phosphates; Male; Myocardial Contracti

1991
[Use of prazosin in the treatment of heart failure in patients with post-infarction cardiosclerosis].
    Kardiologiia, 1990, Volume: 30, Issue:12

    Topics: Adult; Aged; Cardiomyopathy, Dilated; Coronary Artery Disease; Female; Hemodynamics; Humans; Male; M

1990
[Study of the relations between prazosin administration schedule for patients with subacute myocardial infarction and the type of central hemodynamics based on pharmacokinetic data].
    Kardiologiia, 1990, Volume: 30, Issue:12

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hemodynamics; H

1990
Increases in alpha-but not beta-adrenoceptors in hypertrophied non-infarcted cardiac muscles from rats with chronic myocardial infarction.
    Japanese journal of pharmacology, 1990, Volume: 53, Issue:4

    Topics: Animals; Body Weight; Cardiomegaly; Coronary Vessels; Dihydroalprenolol; Male; Muscle Proteins; Myoc

1990
Alpha-adrenergic influences in canine ischemic sudden death: effects of alpha 1-adrenoceptor blockade with prazosin.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Dogs; Electrophysiology; Hemodynamics;

1987
Current indications for vasodilator therapy for left ventricular failure.
    Comprehensive therapy, 1985, Volume: 11, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Drug Therapy, Combination; Heart Failure; Hemodynamics; Hu

1985
[Effect of peripheral vasodilators on the local contractile function of the myocardium in patients with post-infarction cardiosclerosis].
    Kardiologiia, 1988, Volume: 28, Issue:10

    Topics: Aged; Captopril; Endomyocardial Fibrosis; Female; Humans; Male; Middle Aged; Myocardial Contraction;

1988
[Prazosin pharmacodynamics and pharmacokinetics in patients with myocardial infarct complicated by heart failure in the subacute period].
    Kardiologiia, 1987, Volume: 27, Issue:12

    Topics: Adult; Aged; Cardiac Catheterization; Drug Tolerance; Electrocardiography; Female; Half-Life; Heart

1987