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prazosin and Cardiovascular Pregnancy Complications

prazosin has been researched along with Cardiovascular Pregnancy Complications in 13 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"To determine whether nifedipine or prazosin is the more appropriate second-line antihypertensive agent in pregnancy."9.09Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial. ( Hall, DR; Odendaal, HJ; Smith, M; Steyn, DW, 2000)
"Prazosin is a selective peripheral alpha 1-adrenoceptor antagonist used in the treatment of hypertension and heart failure."7.68[Weak transplacental passage of prazosin (Alpress) during the third trimester of pregnancy. 3 cases]. ( Bourget, P; Edouard, D; Fernandez, H; Frydman, R; Ribou, F, 1993)
"The combination of prazosin (3-21 mg/day) and oxprenolol (60-360 mg/day) was used to treat 25 pregnant women with severe essential hypertension and 19 women with the hypertension-oedema-proteinuria syndrome."7.66Combined alpha- and beta-adrenoceptor antagonism with prazosin and oxprenolol in control of severe hypertension in pregnancy. ( Hodge, JV; Lubbe, WF, 1981)
"The disposition and effect of orally administered prazosin have been studied in eight women with hypertension which was uncontrolled by beta-adrenoceptor blockade during the last trimester of pregnancy."7.66Clinical pharmacological studies with prazosin during pregnancy complicated by hypertension. ( Butters, L; Low, RA; Reid, JL; Rubin, PC, 1983)
"Prazosin (Minipress; Pfizer), the first purely alpha-blocking antihypertensive agent, was used to treat 22 pregnant patients with moderately severe hypertension (diastolic blood pressure persistently above 95 mmHg at gestational ages ranging from 18 to 33 weeks)."7.66Prazosin and oxprenolol therapy in pregnancy hypertension. ( Davey, DA; Dommisse, J; Roos, PJ, 1983)
"To determine whether nifedipine or prazosin is the more appropriate second-line antihypertensive agent in pregnancy."5.09Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial. ( Hall, DR; Odendaal, HJ; Smith, M; Steyn, DW, 2000)
"Prazosin is a selective peripheral alpha 1-adrenoceptor antagonist used in the treatment of hypertension and heart failure."3.68[Weak transplacental passage of prazosin (Alpress) during the third trimester of pregnancy. 3 cases]. ( Bourget, P; Edouard, D; Fernandez, H; Frydman, R; Ribou, F, 1993)
"The combination of prazosin (3-21 mg/day) and oxprenolol (60-360 mg/day) was used to treat 25 pregnant women with severe essential hypertension and 19 women with the hypertension-oedema-proteinuria syndrome."3.66Combined alpha- and beta-adrenoceptor antagonism with prazosin and oxprenolol in control of severe hypertension in pregnancy. ( Hodge, JV; Lubbe, WF, 1981)
"The disposition and effect of orally administered prazosin have been studied in eight women with hypertension which was uncontrolled by beta-adrenoceptor blockade during the last trimester of pregnancy."3.66Clinical pharmacological studies with prazosin during pregnancy complicated by hypertension. ( Butters, L; Low, RA; Reid, JL; Rubin, PC, 1983)
"Prazosin (Minipress; Pfizer), the first purely alpha-blocking antihypertensive agent, was used to treat 22 pregnant patients with moderately severe hypertension (diastolic blood pressure persistently above 95 mmHg at gestational ages ranging from 18 to 33 weeks)."3.66Prazosin and oxprenolol therapy in pregnancy hypertension. ( Davey, DA; Dommisse, J; Roos, PJ, 1983)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199010 (76.92)18.7374
1990's2 (15.38)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lubbe, WF3
Hodge, JV2
Rubin, PC2
Butters, L1
Low, RA1
Reid, JL1
Dommisse, J1
Davey, DA1
Roos, PJ1
Kellaway, GS1
Berkowitz, RL1
Bourget, P1
Fernandez, H1
Ribou, F1
Edouard, D1
Frydman, R1
Hall, DR2
Odendaal, HJ2
Steyn, DW1
Smith, M1
Durando, C1
Leidi, L1
Margaria, E1
Medaglia, M1
Gessa, M1
Maina, G1
Redgrave, JE1
Swartz, SL1

Reviews

2 reviews available for prazosin and Cardiovascular Pregnancy Complications

ArticleYear
Anti-hypertensive drugs in the pregnant patient.
    Obstetrical & gynecological survey, 1980, Volume: 35, Issue:4

    Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide

1980
Treatment of hypertension in pregnancy.
    Clinics in obstetrics and gynaecology, 1986, Volume: 13, Issue:2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsia; Female; Human

1986

Trials

2 trials available for prazosin and Cardiovascular Pregnancy Complications

ArticleYear
The addition of a diuretic to anti-hypertensive therapy for early severe hypertension in pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1998, Volume: 60, Issue:1

    Topics: Adult; Amiloride; Antihypertensive Agents; Diuretics; Drug Combinations; Drug Therapy, Combination;

1998
Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial.
    BJOG : an international journal of obstetrics and gynaecology, 2000, Volume: 107, Issue:6

    Topics: Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertension; Ni

2000

Other Studies

9 other studies available for prazosin and Cardiovascular Pregnancy Complications

ArticleYear
Combined alpha- and beta-adrenoceptor antagonism with prazosin and oxprenolol in control of severe hypertension in pregnancy.
    The New Zealand medical journal, 1981, Sep-09, Volume: 94, Issue:691

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Drug Therapy, Combination

1981
Clinical pharmacological studies with prazosin during pregnancy complicated by hypertension.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Female; Humans; Hypertension; Prazosin; Pregnancy; Pregnancy Complications, Cardi

1983
Prazosin and oxprenolol therapy in pregnancy hypertension.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1983, Aug-13, Volume: 64, Issue:7

    Topics: Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertension; Oxprenolol; Prazosin; Pregn

1983
Antihypertensive treatment and fetal welfare in essential hypertension in pregnancy: a retrospective survey of experience with various regimes at National Women's Hospital, Auckland, 1970-80.
    The New Zealand medical journal, 1982, Jan-13, Volume: 95, Issue:699

    Topics: Antihypertensive Agents; Bed Rest; Benzothiadiazines; Birth Weight; Diuretics; Drug Therapy, Combina

1982
The management of hypertension in pregnancy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Mar-07, Volume: 59, Issue:10

    Topics: Adult; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hypertension; Oxprenolol; Prazosin;

1981
[Weak transplacental passage of prazosin (Alpress) during the third trimester of pregnancy. 3 cases].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1993, Volume: 22, Issue:8

    Topics: Adult; Delayed-Action Preparations; Drug Monitoring; Female; Fetal Blood; Humans; Hypertension; Mate

1993
The role of prazosin in the management of hypertension.
    The Medical journal of Australia, 1977, Aug-27, Volume: 2, Issue:2 Suppl

    Topics: Adolescent; Adrenergic beta-Antagonists; Anesthesia, General; Child; Coronary Disease; Diuretics; Dr

1977
[Hypertension in pregnancy: proposed monitoring and therapy].
    Minerva ginecologica, 1985, Volume: 37, Issue:10

    Topics: Adrenergic beta-Antagonists; Captopril; Diuretics; Female; Follow-Up Studies; Humans; Hydralazine; H

1985
Diagnosis and management of malignant hypertension.
    Comprehensive therapy, 1985, Volume: 11, Issue:3

    Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Malignant; Kidney Function Tests

1985