prazosin has been researched along with Asthma in 16 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of prazosin therapy were recently evaluated in ambulatory patients with essential hypertension and chronic obstructive pulmonary disease." | 9.06 | Prazosin in hypertensive patients with chronic bronchitis and asthma: a brief report. ( Chodosh, S; Pizzuto, D; Tuck, J, 1989) |
| "The role of prazosin, an alpha 1 adrenoceptor blocker, was investigated in patients with chronic stable asthma who continued to have symptoms despite conventional treatment." | 9.06 | Prazosin in the treatment of chronic asthma. ( Aitman, TJ; Baudouin, SV; Johnson, AJ, 1988) |
| "The effect of prazosin, a potent and specific alpha 1-adrenoceptor antagonist given by inhalation (total nebulized 2 mg) was compared with placebo in a double-blind randomized study of 10 atopic asthmatic children." | 9.05 | Prazosin, an alpha 1-adrenoceptor antagonist, partially inhibits exercise-induced asthma. ( Barnes, PJ; Vickers, H; Wilson, NM, 1981) |
| "Prazosin, a potent and selective alpha-adrenergic antagonist, was given by inhalation to nine asthmatic subjects aged 25-48 years (six with positive skin tests)." | 9.05 | Inhaled prazosin in asthma. ( Barnes, PJ; Dollery, CT; Ind, PW, 1981) |
| "Low levels of [3H]-dihydroergocryptine (DHE) (alpha adrenergic receptor) binding to peripheral blood mononuclear leukocytes from asthmatic subjects were significantly increased following incubation with histamine." | 7.68 | Effects of histamine on alpha adrenergic receptor expression on the lymphocytes of normal and asthmatic subjects. ( Easton, JG; Goldberg, BJ; Herman, FF; Kaplan, M; Lad, PM; Neidzin, H, 1990) |
| "The effect of 1 mg inhaled prazosin on bronchoconstriction induced by methoxamine was investigated in seven asthmatic subjects." | 7.67 | The action of prazosin and propylene glycol on methoxamine-induced bronchoconstriction in asthmatic subjects. ( Black, JL; Salome, C; Shaw, J; Yan, K, 1984) |
| "The animal and human pharmacology of several new drugs (prazosin, trimazosin, pirbuterol, and carbazeran) useful in the treatment of congestive heart failure (CHF) is delineated in relation to the pharmacology of other agents employed for CHF management." | 6.15 | Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure. ( Baird, JR; Blackburn, KJ; Cambridge, D; Constantine, JW; Ghaly, MS; Hayden, ML; McIlhenny, HM; Moore, PF; Olukotun, AY; Pullman, LG; Salsburg, DS; Saxton, CA; Shevde, S; Taylor, CR, 1981) |
| " This doxazosin dosage reduced the diastolic blood pressure on average from 103 to 91 mmHg (P = 0." | 5.28 | Doxazosin, a new alpha-1-antagonist drug, controls hypertension without causing airways obstruction in asthma and COPD. ( Biernacki, W; Flenley, DC, 1989) |
| "The effects of prazosin therapy were recently evaluated in ambulatory patients with essential hypertension and chronic obstructive pulmonary disease." | 5.06 | Prazosin in hypertensive patients with chronic bronchitis and asthma: a brief report. ( Chodosh, S; Pizzuto, D; Tuck, J, 1989) |
| "The role of prazosin, an alpha 1 adrenoceptor blocker, was investigated in patients with chronic stable asthma who continued to have symptoms despite conventional treatment." | 5.06 | Prazosin in the treatment of chronic asthma. ( Aitman, TJ; Baudouin, SV; Johnson, AJ, 1988) |
| "The effect of prazosin, a potent and specific alpha 1-adrenoceptor antagonist given by inhalation (total nebulized 2 mg) was compared with placebo in a double-blind randomized study of 10 atopic asthmatic children." | 5.05 | Prazosin, an alpha 1-adrenoceptor antagonist, partially inhibits exercise-induced asthma. ( Barnes, PJ; Vickers, H; Wilson, NM, 1981) |
| "Prazosin, a potent and selective alpha-adrenergic antagonist, was given by inhalation to nine asthmatic subjects aged 25-48 years (six with positive skin tests)." | 5.05 | Inhaled prazosin in asthma. ( Barnes, PJ; Dollery, CT; Ind, PW, 1981) |
| "Low levels of [3H]-dihydroergocryptine (DHE) (alpha adrenergic receptor) binding to peripheral blood mononuclear leukocytes from asthmatic subjects were significantly increased following incubation with histamine." | 3.68 | Effects of histamine on alpha adrenergic receptor expression on the lymphocytes of normal and asthmatic subjects. ( Easton, JG; Goldberg, BJ; Herman, FF; Kaplan, M; Lad, PM; Neidzin, H, 1990) |
| "The effect of 1 mg inhaled prazosin on bronchoconstriction induced by methoxamine was investigated in seven asthmatic subjects." | 3.67 | The action of prazosin and propylene glycol on methoxamine-induced bronchoconstriction in asthmatic subjects. ( Black, JL; Salome, C; Shaw, J; Yan, K, 1984) |
| " The autoradiographic distribution of alpha 1-adrenoceptors was investigated in non-diseased and asthmatic human lung by use of [3H]-prazosin (H-PZ)." | 3.67 | Alpha 1-adrenoceptor function and autoradiographic distribution in human asthmatic lung. ( Goldie, RG; Paterson, JW; Rigby, PJ; Spina, D, 1989) |
| "Viable lymphocytes were used to investigate the binding of physiological concentrations of hormones and therapeutic concentrations of anti-asthmatic drugs to [3H]dihydroalprenolol (DHA, beta antagonist) and [3H]prazosin (alpha antagonist) receptor sites." | 3.67 | Modulation of lymphocyte adrenergic receptors by hormones and anti-asthmatic drugs. ( Davies, BH; Williams, WR, 1985) |
| " This doxazosin dosage reduced the diastolic blood pressure on average from 103 to 91 mmHg (P = 0." | 1.28 | Doxazosin, a new alpha-1-antagonist drug, controls hypertension without causing airways obstruction in asthma and COPD. ( Biernacki, W; Flenley, DC, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (93.75) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marlin, GE | 2 |
| Thompson, PJ | 2 |
| Chow, CM | 2 |
| Reddel, HK | 2 |
| Cheng, S | 2 |
| Barnes, P | 1 |
| Barnes, PJ | 3 |
| Wilson, NM | 1 |
| Vickers, H | 1 |
| Ind, PW | 1 |
| Dollery, CT | 2 |
| Kincaid-Smith, P | 1 |
| MacDermot, J | 1 |
| Black, JL | 1 |
| Salome, C | 1 |
| Yan, K | 1 |
| Shaw, J | 1 |
| Taylor, CR | 1 |
| Baird, JR | 1 |
| Blackburn, KJ | 1 |
| Cambridge, D | 1 |
| Constantine, JW | 1 |
| Ghaly, MS | 1 |
| Hayden, ML | 1 |
| McIlhenny, HM | 1 |
| Moore, PF | 1 |
| Olukotun, AY | 1 |
| Pullman, LG | 1 |
| Salsburg, DS | 1 |
| Saxton, CA | 1 |
| Shevde, S | 1 |
| Herman, FF | 1 |
| Goldberg, BJ | 1 |
| Lad, PM | 1 |
| Neidzin, H | 1 |
| Kaplan, M | 1 |
| Easton, JG | 1 |
| Spina, D | 1 |
| Rigby, PJ | 1 |
| Paterson, JW | 1 |
| Goldie, RG | 1 |
| Biernacki, W | 1 |
| Flenley, DC | 1 |
| Chodosh, S | 1 |
| Tuck, J | 1 |
| Pizzuto, D | 1 |
| Williams, WR | 1 |
| Davies, BH | 1 |
| Baudouin, SV | 1 |
| Aitman, TJ | 1 |
| Johnson, AJ | 1 |
| Riabova, KG | 1 |
| Pashkova, TL | 1 |
| Bichev, AA | 1 |
1 review available for prazosin and Asthma
| Article | Year |
|---|---|
Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure.
Topics: Animals; Asthma; Carbamates; Cardiotonic Agents; Cardiovascular Agents; Clinical Trials as Topic; Dr | 1981 |
7 trials available for prazosin and Asthma
| Article | Year |
|---|---|
Bronchodilator action of prazosin.
Topics: Adult; Asthma; Bronchi; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Female | 1981 |
Prazosin as bronchodilator.
Topics: Asthma; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Humans; Prazosin; Quin | 1981 |
Prazosin, an alpha 1-adrenoceptor antagonist, partially inhibits exercise-induced asthma.
Topics: Adolescent; Adrenergic alpha-Agonists; Asthma; Asthma, Exercise-Induced; Child; Clinical Trials as T | 1981 |
Inhaled prazosin in asthma.
Topics: Adrenergic alpha-Antagonists; Adult; Albuterol; Asthma; Clinical Trials as Topic; Double-Blind Metho | 1981 |
Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure.
Topics: Animals; Asthma; Carbamates; Cardiotonic Agents; Cardiovascular Agents; Clinical Trials as Topic; Dr | 1981 |
Prazosin in hypertensive patients with chronic bronchitis and asthma: a brief report.
Topics: Asthma; Blood Pressure; Bronchitis; Chronic Disease; Forced Expiratory Volume; Humans; Hypertension; | 1989 |
Prazosin in the treatment of chronic asthma.
Topics: Adolescent; Adult; Aged; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expir | 1988 |
9 other studies available for prazosin and Asthma
| Article | Year |
|---|---|
Beta-adrenergic receptor blocking drugs in hypertension. With special reference to their use as initial therapy.
Topics: Adrenergic beta-Antagonists; Asthma; Central Nervous System; Depression, Chemical; Heart Failure; Hu | 1984 |
Increased pulmonary alpha-adrenergic and reduced beta-adrenergic receptors in experimental asthma.
Topics: Adenylyl Cyclases; Animals; Asthma; Dihydroalprenolol; Disease Models, Animal; Enzyme Activation; Gu | 1980 |
The action of prazosin and propylene glycol on methoxamine-induced bronchoconstriction in asthmatic subjects.
Topics: Adult; Aged; Asthma; Female; Forced Expiratory Volume; Histamine; Humans; Male; Methoxamine; Middle | 1984 |
Bronchodilator activity of prazosin in patients with allergic rhinitis and asthma.
Topics: Adult; Aged; Asthma; Blood Pressure; Bronchodilator Agents; Double-Blind Method; Female; Forced Expi | 1982 |
Effects of histamine on alpha adrenergic receptor expression on the lymphocytes of normal and asthmatic subjects.
Topics: Asthma; Dihydroalprenolol; Dihydroergotoxine; Dose-Response Relationship, Drug; Histamine; Humans; M | 1990 |
Alpha 1-adrenoceptor function and autoradiographic distribution in human asthmatic lung.
Topics: Adult; Asthma; Autoradiography; Bronchi; Carbachol; Humans; In Vitro Techniques; Iodine Radioisotope | 1989 |
Doxazosin, a new alpha-1-antagonist drug, controls hypertension without causing airways obstruction in asthma and COPD.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Asthma; Blood Pressure; Doxazosin; Female; Forced Expirat | 1989 |
Modulation of lymphocyte adrenergic receptors by hormones and anti-asthmatic drugs.
Topics: Asthma; Binding, Competitive; Dihydroalprenolol; Hormones; Humans; Kinetics; Lymphocytes; Prazosin; | 1985 |
[Effect of the alpha-adrenergic blockader prazosin on physical effort-induced bronchospasm in bronchial asthma].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Drug Evaluation; Exercise Test; Female; Humans; | 1988 |