prazosin has been researched along with Aortic Valve Insufficiency in 13 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Therapy with prazosin can improve the condition of patients with congestive heart failure due to its vasodilating action." | 3.66 | Noninvasive assessment of left ventricular wall stress in chronic congestive heart failure patients. ( Abdou, O; Chandy, F; Gopalaswamy, C; Gould, L, 1983) |
| "Seventeen patients with chronic aortic regurgitation (AR) were examined by echocardiography and left and right heart catheterization." | 1.27 | Unloading effects of prazosin in patients with chronic aortic regurgitation. ( Henzlová, M; Jebavý, P; Koudelková, E, 1983) |
| "In this group of patients with severe aortic regurgitation but without severe cardiac failure, the changes with either drug, studied in doses conventionally used, were small but those with prazosin were directionally more desirable than those resulting from digoxin." | 1.26 | Comparison of vasodilator drug prazosin with digoxin in aortic regurgitation. ( Clarke, GM; Cope, GD; Hockings, BE; Taylor, RR, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rumiński, W | 1 |
| Markiewicz, M | 1 |
| Przegaliński, J | 1 |
| Sterz, H | 1 |
| Cohn, JN | 1 |
| Juillard, A | 1 |
| Batalla, N | 1 |
| Leroy, G | 1 |
| Fernandez, F | 1 |
| Gerbaux, A | 1 |
| Gould, L | 1 |
| Gopalaswamy, C | 1 |
| Chandy, F | 1 |
| Abdou, O | 1 |
| Jebavý, P | 3 |
| Koudelková, E | 3 |
| Henzlová, M | 1 |
| Chatterjee, K | 1 |
| Rouleau, JL | 1 |
| Massie, BM | 1 |
| Hockings, BE | 1 |
| Cope, GD | 1 |
| Clarke, GM | 1 |
| Taylor, RR | 1 |
| Lavítola, Pde L | 1 |
| de Moraes, AV | 1 |
| Dallan, L | 1 |
| Grinberg, M | 1 |
| Sosa, EA | 1 |
| Higa, SS | 1 |
| Bessegato, L | 1 |
| Pileggi, F | 1 |
| Kozáková, M | 1 |
| Poch, T | 1 |
| Jalil, J | 1 |
| Escobar, E | 1 |
| Thumala, A | 1 |
| Domenech, R | 1 |
| Venegas, P | 1 |
1 review available for prazosin and Aortic Valve Insufficiency
| Article | Year |
|---|---|
Vasodilator therapy of congestive heart failure.
Topics: Aortic Valve Insufficiency; Captopril; Dobutamine; Heart Failure; Humans; Hydralazine; Isosorbide Di | 1980 |
1 trial available for prazosin and Aortic Valve Insufficiency
| Article | Year |
|---|---|
[Comparative study of vasodilator drugs in heart valve diseases].
Topics: Adolescent; Adult; Aortic Valve Insufficiency; Clinical Trials as Topic; Echocardiography; Female; H | 1987 |
11 other studies available for prazosin and Aortic Valve Insufficiency
| Article | Year |
|---|---|
[Hemodynamic effect of prazosin in patients with aortic and mitral valve insufficiency].
Topics: Adult; Aortic Valve Insufficiency; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; M | 1983 |
[Causes of acute valve-conditioned left ventricular insufficiency-- attempt at a tabulated review].
Topics: Aortic Valve Insufficiency; Cardiac Glycosides; Dyspnea; Endocarditis, Bacterial; Humans; Hydralazin | 1984 |
[Hemodynamic effects of a single dose of prazosin in 8 cases of mitral or aortic regurgitation].
Topics: Adult; Aortic Valve Insufficiency; Female; Hemodynamics; Humans; Male; Mitral Valve Insufficiency; P | 1981 |
Noninvasive assessment of left ventricular wall stress in chronic congestive heart failure patients.
Topics: Adult; Aged; Aortic Valve Insufficiency; Blood Pressure; Echocardiography; Female; Heart; Heart Fail | 1983 |
Unloading effects of prazosin in patients with chronic aortic regurgitation.
Topics: Adolescent; Adult; Aortic Valve Insufficiency; Cardiac Catheterization; Cardiac Output; Echocardiogr | 1983 |
Hydralazine in chronic CHF.
Topics: Administration, Oral; Aortic Valve Insufficiency; Cardiac Output; Chronic Disease; Drug Therapy, Com | 1981 |
[Effect of prazosin on aortal regurgitation (author's transl)].
Topics: Administration, Oral; Adolescent; Adult; Aortic Valve Insufficiency; Female; Humans; Male; Middle Ag | 1980 |
Comparison of vasodilator drug prazosin with digoxin in aortic regurgitation.
Topics: Adult; Aortic Valve Insufficiency; Digoxin; Female; Hemodynamics; Humans; Male; Middle Aged; Prazosi | 1980 |
[Echocardiographic evaluation of the effect of prazosin in aortic insufficiency (author's transl)].
Topics: Adult; Aortic Valve Insufficiency; Echocardiography; Humans; Middle Aged; Prazosin; Quinazolines | 1980 |
[The effect of vasodilator therapy on mitral and aortic insufficiency in a Doppler echocardiography study].
Topics: Adult; Aged; Aged, 80 and over; Aortic Valve Insufficiency; Echocardiography; Female; Humans; Male; | 1987 |
[Vasodilator agents in chronic asymptomatic aortic insufficiency: echocardiographic study].
Topics: Adult; Aged; Aortic Valve Insufficiency; Captopril; Chronic Disease; Echocardiography; Female; Hemod | 1985 |