Page last updated: 2024-11-03

prazosin and Angor Pectoris

prazosin has been researched along with Angor Pectoris in 15 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"We describe a 71-year-old male patient who developed acute myocardial infarction (AMI) due to a dynamic left ventricular outflow tract obstruction induced by terazosin."7.83Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report. ( Ferrando-Castagnetto, F; Lluberas, N; Martínez, F; Vidal Margenat, A; Vignolo, G, 2016)
"A case of angina pectoris worsened by prazosin is presented."7.66Exacerbation of angina pectoris by prazosin. ( Charness, ME; Fishman, JA; Robertson, D, 1979)
"We describe a 71-year-old male patient who developed acute myocardial infarction (AMI) due to a dynamic left ventricular outflow tract obstruction induced by terazosin."3.83Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report. ( Ferrando-Castagnetto, F; Lluberas, N; Martínez, F; Vidal Margenat, A; Vignolo, G, 2016)
"A case of angina pectoris worsened by prazosin is presented."3.66Exacerbation of angina pectoris by prazosin. ( Charness, ME; Fishman, JA; Robertson, D, 1979)
"Pretreatment with prazosin (300 μg/kg IV) allowed determination of α(1)-adrenergic receptor involvement (n=8)."1.37Ranolazine injection into coronary or femoral arteries exerts marked, transient regional vasodilation without systemic hypotension in an intact porcine model. ( Belardinelli, L; Nieminen, T; Pegler, JR; Tavares, CA; Verrier, RL, 2011)
" The LD50 value for adrenaline in control animals was 11."1.27Adrenaline toxicity in mice: sensitization of alpha 1 adrenoreceptors by nitroglycerin. ( Axelsson, KL; Rydell, EL, 1984)
"Prazosin was well tolerated except in one patient who experienced worsening angina."1.26Antihypertensive therapy with prazosin in patients with left ventricular dysfunction. Improvement in cardiac performance and exercise tolerance. ( Chan, S; Massie, BM, 1981)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's4 (26.67)18.2507
2000's0 (0.00)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vidal Margenat, A1
Ferrando-Castagnetto, F1
Martínez, F1
Lluberas, N1
Vignolo, G1
Nieminen, T1
Tavares, CA1
Pegler, JR1
Belardinelli, L1
Verrier, RL1
Rydell, EL1
Axelsson, KL1
Heinecker, R1
Robertson, RM1
Bernard, YD1
Carr, RK1
Robertson, D2
Opie, LH1
Ellingsen, O1
Kjekshus, J1
Massie, BM1
Chan, S1
Liusov, VA1
Volov, NA1
Dibirova, GO1
Uteshev, DB1
Fujita, M1
Tanaka, T1
Nakae, I1
Tamaki, S1
Kihara, Y1
Nohara, R1
Sasayama, S1
Enenkel, W1
Charness, ME1
Fishman, JA1
Steen, S1
Willén, R1
Sjöberg, T1
Carlén, B1
Piatak, OA1
Yanovskii, GV1
Lizogub, VG1
Galassi, AR1
Kaski, JC1
Pupita, G1
Vejar, M1
Crea, F1
Maseri, A1

Reviews

1 review available for prazosin and Angor Pectoris

ArticleYear
[Cardiac therapy in the old patient].
    Wiener medizinische Wochenschrift (1946), 1979, Oct-10, Volume: 129, Issue:18

    Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Body Water; Calcium; Clonidine; Digitalis Glycos

1979

Trials

3 trials available for prazosin and Angor Pectoris

ArticleYear
Alpha-adrenergic blockade in vasotonic angina: lack of efficacy of specific alpha 1-receptor blockade with prazosin.
    Journal of the American College of Cardiology, 1983, Volume: 2, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Vasos

1983
[Prazosin in exercise-induced angina pectoris. An open study of work capacity after a single dose of prazosin, isosorbide dinitrate, atenolol and nifedipine].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1984, Mar-30, Volume: 104, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Atenolol; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Age

1984
The influence of adrenoreactive preparations on clinical and haemodynamic parameters in patients with ischaemic heart disease.
    Cor et vasa, 1991, Volume: 33, Issue:1

    Topics: Adult; Angina Pectoris; Coronary Artery Disease; Coronary Disease; Double-Blind Method; Exercise Tes

1991

Other Studies

11 other studies available for prazosin and Angor Pectoris

ArticleYear
Myocardial infarction induced by oral terazosin in a patient with predisposing structural cardiomyopathy: case report.
    Medwave, 2016, Jun-28, Volume: 16, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Angina Pectoris; Cardiomyopathies; Coronary Angiograp

2016
Ranolazine injection into coronary or femoral arteries exerts marked, transient regional vasodilation without systemic hypotension in an intact porcine model.
    Circulation. Cardiovascular interventions, 2011, Oct-01, Volume: 4, Issue:5

    Topics: Acetanilides; Adrenergic alpha-1 Receptor Agonists; Angina Pectoris; Animals; Blood Pressure; Corona

2011
Adrenaline toxicity in mice: sensitization of alpha 1 adrenoreceptors by nitroglycerin.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:1

    Topics: Angina Pectoris; Animals; Coronary Vessels; Epinephrine; Humans; Male; Mice; Mice, Inbred Strains; N

1984
[Frequent errors in the therapy of heart disease].
    Wiener medizinische Wochenschrift (1946), 1982, Nov-30, Volume: 132, Issue:22

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biologic

1982
Calcium ions, drug action and the heart--with special reference to calcium antagonist drugs.
    Pharmacology & therapeutics, 1984, Volume: 25, Issue:3

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channe

1984
Antihypertensive therapy with prazosin in patients with left ventricular dysfunction. Improvement in cardiac performance and exercise tolerance.
    Chest, 1981, Volume: 80, Issue:6

    Topics: Aged; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Dizziness; Exercise Test; Headache;

1981
[The prognosis of drug therapy efficacy in ventricular rhythm disorders by the level of intracellular Ca2+ in the lymphocytes of patients with ischemic heart disease].
    Kardiologiia, 1993, Volume: 33, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Calcium; Drug Evaluation; Drug Therapy, Combinat

1993
Importance of alpha 1-sympathetic activity for diurnal change in ischemic threshold in patients with stable angina.
    Clinical cardiology, 1998, Volume: 21, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Amlodipine; Analysis of Variance; Angina Pectoris; Calciu

1998
Exacerbation of angina pectoris by prazosin.
    Southern medical journal, 1979, Volume: 72, Issue:9

    Topics: Acute Disease; Aged; Angina Pectoris; Blood Pressure; Heart Failure; Humans; Hypertension; Male; Pra

1979
Contractile and morphologic properties of a saphenous vein after 12 years as an aortocoronary bypass graft.
    Blood vessels, 1991, Volume: 28, Issue:5

    Topics: Angina Pectoris; Coronary Artery Bypass; Humans; Male; Microscopy, Electron; Microscopy, Electron, S

1991
Lack of evidence for alpha-adrenergic receptor-mediated mechanisms in the genesis of ischemia in syndrome X.
    The American journal of cardiology, 1989, Aug-01, Volume: 64, Issue:5

    Topics: Adult; Angina Pectoris; Clonidine; Coronary Angiography; Coronary Disease; Electrocardiography; Exer

1989