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prazosin and Allergic Encephalomyelitis

prazosin has been researched along with Allergic Encephalomyelitis in 5 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"The effectiveness of the alpha 1-adrenergic antagonist prazosin for preventing monoaminergic axonal damage in the spinal cords of rats that were inoculated for experimental allergic encephalomyelitis (EAE) was assessed using immunohistochemistry."7.68Prazosin suppresses development of axonal damage in rats inoculated for experimental allergic encephalomyelitis. ( Black, PC; Paros, KC; Samathanam, GK; White, SR, 1992)
"The effectiveness of the alpha 1-adrenergic antagonist prazosin for preventing monoaminergic axonal damage in the spinal cords of rats that were inoculated for experimental allergic encephalomyelitis (EAE) was assessed using immunohistochemistry."3.68Prazosin suppresses development of axonal damage in rats inoculated for experimental allergic encephalomyelitis. ( Black, PC; Paros, KC; Samathanam, GK; White, SR, 1992)
"Treatment with prazosin was also able to suppress clinical and histological signs of EAE in animals sensitized by adoptive transfer with activated spleen or lymph node cells."1.27Prazosin, an alpha 1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat. ( Bloom, BR; Brosnan, CF; Cammer, W; Factor, SM; Goldmuntz, EA; Norton, WT, 1985)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
White, SR1
Black, PC1
Samathanam, GK1
Paros, KC1
Brosnan, CF4
Goldmuntz, EA4
Cammer, W1
Factor, SM1
Bloom, BR1
Norton, WT4
Sacks, HJ1
Goldschmidt, RC1
Chiu, FC1

Other Studies

5 other studies available for prazosin and Allergic Encephalomyelitis

ArticleYear
Prazosin suppresses development of axonal damage in rats inoculated for experimental allergic encephalomyelitis.
    Journal of neuroimmunology, 1992, Volume: 39, Issue:3

    Topics: Animals; Axons; Encephalomyelitis, Autoimmune, Experimental; Male; Myelitis; Prazosin; Rats; Rats, I

1992
Prazosin, an alpha 1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:17

    Topics: Animals; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Female; Immu

1985
Prazosin treatment during the effector stage of disease suppresses experimental autoimmune encephalomyelitis in the Lewis rat.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Dec-01, Volume: 137, Issue:11

    Topics: Animals; Capillary Permeability; Drug Administration Schedule; Encephalomyelitis, Autoimmune, Experi

1986
Astrocytic reactivity and intermediate filament metabolism in experimental autoimmune encephalomyelitis: the effect of suppression with prazosin.
    Brain research, 1986, Nov-05, Volume: 397, Issue:1

    Topics: Animals; Astrocytes; Encephalomyelitis, Autoimmune, Experimental; Glial Fibrillary Acidic Protein; H

1986
Prazosin treatment suppresses increased vascular permeability in both acute and passively transferred experimental autoimmune encephalomyelitis in the Lewis rat.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Dec-01, Volume: 137, Issue:11

    Topics: Animals; Blood-Brain Barrier; Capillary Permeability; DNA; Edema; Encephalomyelitis, Autoimmune, Exp

1986