prazosin has been researched along with Allergic Encephalomyelitis in 5 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Excerpt | Relevance | Reference |
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"The effectiveness of the alpha 1-adrenergic antagonist prazosin for preventing monoaminergic axonal damage in the spinal cords of rats that were inoculated for experimental allergic encephalomyelitis (EAE) was assessed using immunohistochemistry." | 7.68 | Prazosin suppresses development of axonal damage in rats inoculated for experimental allergic encephalomyelitis. ( Black, PC; Paros, KC; Samathanam, GK; White, SR, 1992) |
"The effectiveness of the alpha 1-adrenergic antagonist prazosin for preventing monoaminergic axonal damage in the spinal cords of rats that were inoculated for experimental allergic encephalomyelitis (EAE) was assessed using immunohistochemistry." | 3.68 | Prazosin suppresses development of axonal damage in rats inoculated for experimental allergic encephalomyelitis. ( Black, PC; Paros, KC; Samathanam, GK; White, SR, 1992) |
"Treatment with prazosin was also able to suppress clinical and histological signs of EAE in animals sensitized by adoptive transfer with activated spleen or lymph node cells." | 1.27 | Prazosin, an alpha 1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat. ( Bloom, BR; Brosnan, CF; Cammer, W; Factor, SM; Goldmuntz, EA; Norton, WT, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (80.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
White, SR | 1 |
Black, PC | 1 |
Samathanam, GK | 1 |
Paros, KC | 1 |
Brosnan, CF | 4 |
Goldmuntz, EA | 4 |
Cammer, W | 1 |
Factor, SM | 1 |
Bloom, BR | 1 |
Norton, WT | 4 |
Sacks, HJ | 1 |
Goldschmidt, RC | 1 |
Chiu, FC | 1 |
5 other studies available for prazosin and Allergic Encephalomyelitis
Article | Year |
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Prazosin suppresses development of axonal damage in rats inoculated for experimental allergic encephalomyelitis.
Topics: Animals; Axons; Encephalomyelitis, Autoimmune, Experimental; Male; Myelitis; Prazosin; Rats; Rats, I | 1992 |
Prazosin, an alpha 1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat.
Topics: Animals; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Female; Immu | 1985 |
Prazosin treatment during the effector stage of disease suppresses experimental autoimmune encephalomyelitis in the Lewis rat.
Topics: Animals; Capillary Permeability; Drug Administration Schedule; Encephalomyelitis, Autoimmune, Experi | 1986 |
Astrocytic reactivity and intermediate filament metabolism in experimental autoimmune encephalomyelitis: the effect of suppression with prazosin.
Topics: Animals; Astrocytes; Encephalomyelitis, Autoimmune, Experimental; Glial Fibrillary Acidic Protein; H | 1986 |
Prazosin treatment suppresses increased vascular permeability in both acute and passively transferred experimental autoimmune encephalomyelitis in the Lewis rat.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; DNA; Edema; Encephalomyelitis, Autoimmune, Exp | 1986 |