Page last updated: 2024-11-03

prazosin and Age-Related Memory Disorders

prazosin has been researched along with Age-Related Memory Disorders in 6 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
" The present studies show that the inhibition of memory by high doses of noradrenaline is mimicked by the alpha1-AR agonist methoxamine, and the dose-response curve is shifted to the right by pretreatment with the alpha1-AR antagonist prazosin."1.31Stimulation of alpha1-adrenoceptors inhibits memory consolidation in the chick. ( Gibbs, ME; Summers, RJ, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kobori, N1
Hu, B1
Dash, PK1
Katsouri, L1
Vizcaychipi, MP1
McArthur, S1
Harrison, I1
Suárez-Calvet, M1
Lleo, A1
Lloyd, DG1
Ma, D1
Sastre, M1
Collier, TJ1
Greene, JG1
Felten, DL1
Stevens, SY1
Collier, KS1
Egashira, N1
Yano, A1
Ishigami, N1
Mishima, K1
Iwasaki, K1
Fujioka, M1
Matsushita, M1
Nishimura, R1
Fujiwara, M1
Stuchlik, A1
Vales, K1
Gibbs, ME1
Summers, RJ1

Other Studies

6 other studies available for prazosin and Age-Related Memory Disorders

ArticleYear
Altered adrenergic receptor signaling following traumatic brain injury contributes to working memory dysfunction.
    Neuroscience, 2011, Jan-13, Volume: 172

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Brain Injuries; Disease Models, Animal; Epinephrin

2011
Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease.
    Neurobiology of aging, 2013, Volume: 34, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease

2013
Reduced cortical noradrenergic neurotransmission is associated with increased neophobia and impaired spatial memory in aged rats.
    Neurobiology of aging, 2004, Volume: 25, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals

2004
Investigation of mechanisms mediating 8-OH-DPAT-induced impairment of spatial memory: involvement of 5-HT1A receptors in the dorsal hippocampus in rats.
    Brain research, 2006, Jan-19, Volume: 1069, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Analysis of Variance; Animals;

2006
Role of alpha1- and alpha2-adrenoceptors in the regulation of locomotion and spatial behavior in the active place avoidance task: a dose-response study.
    Neuroscience letters, 2008, Mar-15, Volume: 433, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A

2008
Stimulation of alpha1-adrenoceptors inhibits memory consolidation in the chick.
    The European journal of neuroscience, 2001, Volume: 14, Issue:8

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anima

2001