prazosin has been researched along with African Sleeping Sickness in 2 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human African trypanosomiasis (HAT) remains a health threat to sub-Saharan Africa." | 1.72 | Identification of Prazosin as a Potential Flagellum Attachment Zone 1(FAZ1) Inhibitor for the Treatment of Human African Trypanosomiasis. ( Afrin, M; Hanna, J; Li, B; Li, Y; Marbury, M; Orahoske, CM; Su, B, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Orahoske, CM | 1 |
| Afrin, M | 1 |
| Li, Y | 1 |
| Hanna, J | 1 |
| Marbury, M | 1 |
| Li, B | 1 |
| Su, B | 1 |
| Khasar, S | 1 |
| Oriowo, MA | 1 |
2 other studies available for prazosin and African Sleeping Sickness
| Article | Year |
|---|---|
Identification of Prazosin as a Potential Flagellum Attachment Zone 1(FAZ1) Inhibitor for the Treatment of Human African Trypanosomiasis.
Topics: Animals; Flagella; Humans; Prazosin; Proteomics; Trypanocidal Agents; Trypanosomiasis, African | 2022 |
Vascular smooth muscle sensitivity to noradrenaline is reduced during an infection with Trypanosoma brucei in rats and rabbits.
Topics: Animals; Arteries; Dose-Response Relationship, Drug; Histamine; Muscle, Smooth, Vascular; Norepineph | 1991 |