prazosin has been researched along with Acute Kidney Failure in 7 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, the effect of Prazosin, an α1-Adrenergic receptor antagonist, was investigated on the liver injury induced by kidney ischemia-reperfusion (I/R) in rats." | 8.31 | Prazosin Protects the Liver Against Renal Ischemia/Reperfusion Injury in Rats. ( Aghajani, S; Bagheri, Y; Bahraminia, F; Jafari, E; Kakaei, F; Khajepour, F; Mahmoodpoor, F; Vahed, SZ, 2023) |
| "With doxazosin treatment, the mean supine and standing SBPs were reduced by 15 mmHg and 13 mmHg, respectively." | 6.67 | An evaluation of the efficacy and safety of doxazosin in the treatment of hypertension associated with renal insufficiency. ( Anderton, JL; Notghi, A, 1990) |
| "Prazosin has shown protective effects against IR-injuries." | 5.72 | Prazosin Treatment Protects Brain and Heart by Diminishing Oxidative Stress and Apoptotic Pathways After Renal Ischemia Reperfusion. ( Aghajani, S; Ahmadian, E; Bagheri, Y; Jeddi, M; Malekinejad, Z; Qahremani, R; Shahbazi, S, 2022) |
| "Prazosin was administered by intraperitoneal injection 30 min prior to IR induction." | 5.62 | Renoprotective effects of prazosin on ischemia-reperfusion injury in rats. ( Bagheri, A; Bagheri, S; Bagheri, Y; Fathi, E; Jafari, S; Montazersaheb, S; Nia, AV; Rahimi, MM, 2021) |
| " In this study, the effect of Prazosin, an α1-Adrenergic receptor antagonist, was investigated on the liver injury induced by kidney ischemia-reperfusion (I/R) in rats." | 4.31 | Prazosin Protects the Liver Against Renal Ischemia/Reperfusion Injury in Rats. ( Aghajani, S; Bagheri, Y; Bahraminia, F; Jafari, E; Kakaei, F; Khajepour, F; Mahmoodpoor, F; Vahed, SZ, 2023) |
| "With doxazosin treatment, the mean supine and standing SBPs were reduced by 15 mmHg and 13 mmHg, respectively." | 2.67 | An evaluation of the efficacy and safety of doxazosin in the treatment of hypertension associated with renal insufficiency. ( Anderton, JL; Notghi, A, 1990) |
| "Prazosin has shown protective effects against IR-injuries." | 1.72 | Prazosin Treatment Protects Brain and Heart by Diminishing Oxidative Stress and Apoptotic Pathways After Renal Ischemia Reperfusion. ( Aghajani, S; Ahmadian, E; Bagheri, Y; Jeddi, M; Malekinejad, Z; Qahremani, R; Shahbazi, S, 2022) |
| "Prazosin was administered by intraperitoneal injection 30 min prior to IR induction." | 1.62 | Renoprotective effects of prazosin on ischemia-reperfusion injury in rats. ( Bagheri, A; Bagheri, S; Bagheri, Y; Fathi, E; Jafari, S; Montazersaheb, S; Nia, AV; Rahimi, MM, 2021) |
| "Mice treated with terazosin had a significant decrease in serum creatinine, urinary Kim-1 levels, HIF-1α, apoptosis, and downstream Adrab1 genes including Ece1, Edn1, pMAPK14 with increased cell proliferation." | 1.62 | Identification of novel therapeutic targets for contrast induced acute kidney injury (CI-AKI): alpha blockers as a therapeutic strategy for CI-AKI. ( Cai, C; Kilari, S; Misra, S; Sharma, A; Simeon, M; Singh, A; van Wijnen, AJ; Zhao, C, 2021) |
| "Ischemic acute renal failure was induced by occlusion of the left renal artery and vein for 45 min followed by reperfusion, 2 weeks after contralateral nephrectomy." | 1.34 | Selective antagonism of the postsynaptic alpha(1)-adrenoceptor is protective against ischemic acute renal failure in rats. ( Fujii, T; Kobuchi, S; Matsumura, Y; Ohkita, M; Sugiura, T; Takaoka, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Malekinejad, Z | 1 |
| Aghajani, S | 2 |
| Jeddi, M | 1 |
| Qahremani, R | 1 |
| Shahbazi, S | 1 |
| Bagheri, Y | 3 |
| Ahmadian, E | 1 |
| Khajepour, F | 1 |
| Mahmoodpoor, F | 1 |
| Jafari, E | 1 |
| Kakaei, F | 1 |
| Bahraminia, F | 1 |
| Vahed, SZ | 1 |
| Rahimi, MM | 1 |
| Bagheri, A | 1 |
| Fathi, E | 1 |
| Bagheri, S | 1 |
| Nia, AV | 1 |
| Jafari, S | 1 |
| Montazersaheb, S | 1 |
| Kilari, S | 1 |
| Sharma, A | 1 |
| Zhao, C | 1 |
| Singh, A | 1 |
| Cai, C | 1 |
| Simeon, M | 1 |
| van Wijnen, AJ | 1 |
| Misra, S | 1 |
| Fujii, T | 1 |
| Sugiura, T | 1 |
| Ohkita, M | 1 |
| Kobuchi, S | 1 |
| Takaoka, M | 1 |
| Matsumura, Y | 1 |
| Bourland, WA | 1 |
| Tobin, HM | 1 |
| Reynolds, DG | 1 |
| Printen, KJ | 1 |
| Anderton, JL | 1 |
| Notghi, A | 1 |
1 trial available for prazosin and Acute Kidney Failure
| Article | Year |
|---|---|
An evaluation of the efficacy and safety of doxazosin in the treatment of hypertension associated with renal insufficiency.
Topics: Acute Kidney Injury; Adult; Blood Pressure; Doxazosin; Female; Heart Rate; Humans; Hypertension; Mal | 1990 |
6 other studies available for prazosin and Acute Kidney Failure
| Article | Year |
|---|---|
Prazosin Treatment Protects Brain and Heart by Diminishing Oxidative Stress and Apoptotic Pathways After Renal Ischemia Reperfusion.
Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Brain; Ischemia; Kidney; Oxidative Stress; Pr | 2022 |
Prazosin Protects the Liver Against Renal Ischemia/Reperfusion Injury in Rats.
Topics: Acute Kidney Injury; Animals; Ischemia; Kidney; Liver; Male; Oxidative Stress; Prazosin; Rats; Rats, | 2023 |
Renoprotective effects of prazosin on ischemia-reperfusion injury in rats.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Cytokines; Kidney; Male; NF-kappa | 2021 |
Identification of novel therapeutic targets for contrast induced acute kidney injury (CI-AKI): alpha blockers as a therapeutic strategy for CI-AKI.
Topics: Acute Kidney Injury; Adrenergic alpha-1 Receptor Antagonists; Animals; Apoptosis; Cell Proliferation | 2021 |
Selective antagonism of the postsynaptic alpha(1)-adrenoceptor is protective against ischemic acute renal failure in rats.
Topics: Acute Kidney Injury; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; | 2007 |
Pancreatitis induced renal vasoconstriction.
Topics: Acute Kidney Injury; Animals; Bile; Disease Models, Animal; Dogs; Female; Fluid Therapy; Male; Pancr | 1982 |