prazosin has been researched along with ANS (Autonomic Nervous System) Diseases in 12 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prazosin was well tolerated and did not produce a significant lowering of resting blood pressure." | 2.67 | A study of the alpha-1 adrenoceptor blocker prazosin in the prophylactic management of autonomic dysreflexia in high spinal cord injury patients. ( Brown, DJ; Howes, LG; Krum, H; Louis, WJ, 1992) |
| "Treatment with hydralazine at hypotensive dose for 12 weeks also failed to affect the proteinuria in 5 of 6 nephrectomized CKD rats." | 1.40 | Involvement of renal sympathetic nerve overactivation in the progression of chronic kidney disease in rats. ( Ayajiki, K; Funai, A; Kobuchi, S; Matsumura, Y; Ohkita, M; Suzuki, R; Tanaka, R; Tsutsui, H; Yazawa, M, 2014) |
| "The mechanism of autonomic hyperreflexia has been thought to be an acute general autonomic overactivity in response to cutaneous or visceral stimuli, but it remains uncertain." | 1.30 | [Induction of noradrenergic supersensitivity following cordotomy in neonatal rat spinal motoneurons]. ( Kadotani, H, 1999) |
| "Terazosin was evaluated in 21 normotensive spinal cord injured patients with autonomic dysreflexia." | 1.29 | Prospective evaluation of terazosin for the treatment of autonomic dysreflexia. ( Chancellor, MB; Erhard, MJ; Hirsch, IH; Stass, WE, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 7 (58.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kobuchi, S | 1 |
| Tanaka, R | 1 |
| Funai, A | 1 |
| Suzuki, R | 1 |
| Yazawa, M | 1 |
| Tsutsui, H | 1 |
| Ohkita, M | 1 |
| Ayajiki, K | 1 |
| Matsumura, Y | 1 |
| Osborn, JW | 2 |
| Collister, JP | 1 |
| Guzman, P | 1 |
| Santajuliana, D | 1 |
| Zukowska-Grojec, Z | 1 |
| Rivas, DA | 1 |
| Chancellor, MB | 2 |
| Huang, B | 1 |
| Salzman, SK | 1 |
| Erhard, MJ | 1 |
| Hirsch, IH | 1 |
| Stass, WE | 1 |
| Murray, A | 1 |
| Pearson, GT | 1 |
| Cottrell, DF | 1 |
| Vaidyanathan, S | 1 |
| Soni, BM | 1 |
| Sett, P | 1 |
| Watt, JW | 1 |
| Oo, T | 1 |
| Bingley, J | 1 |
| Kadotani, H | 1 |
| Gallego, M | 1 |
| Casis, E | 1 |
| Izquierdo, MJ | 1 |
| Casis, O | 1 |
| Krum, H | 1 |
| Louis, WJ | 1 |
| Brown, DJ | 1 |
| Howes, LG | 1 |
| Rochette, G | 1 |
| Lecomte, J | 1 |
| Onrot, J | 1 |
| Goldberg, MR | 1 |
| Biaggioni, I | 1 |
| Hollister, AS | 1 |
| Kincaid, D | 1 |
| Robertson, D | 1 |
2 trials available for prazosin and ANS (Autonomic Nervous System) Diseases
| Article | Year |
|---|---|
Pathophysiology of autonomic dysreflexia: long-term treatment with terazosin in adult and paediatric spinal cord injury patients manifesting recurrent dysreflexic episodes.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Autonomic Nervous System Diseases; Child; Dose-Resp | 1998 |
A study of the alpha-1 adrenoceptor blocker prazosin in the prophylactic management of autonomic dysreflexia in high spinal cord injury patients.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Autonomic Nervous System Diseases; Blood Pressure; | 1992 |
10 other studies available for prazosin and ANS (Autonomic Nervous System) Diseases
| Article | Year |
|---|---|
Involvement of renal sympathetic nerve overactivation in the progression of chronic kidney disease in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Autonom | 2014 |
Effect of peripheral sympathetic nerve dysfunction on salt sensitivity of arterial pressure.
Topics: Animals; Antihypertensive Agents; Autonomic Nervous System Diseases; Blood Pressure; Dose-Response R | 2008 |
Contribution of alpha- and beta- adrenoceptors and neuropeptide-Y to autonomic dysreflexia.
Topics: Animals; Autonomic Nervous System Diseases; Blood Pressure; Ganglionic Blockers; Heart Rate; Hexamet | 1995 |
Autonomic dysreflexia in a rat model spinal cord injury and the effect of pharmacologic agents.
Topics: Adrenergic alpha-Antagonists; Animals; Autonomic Nervous System Diseases; Calcium Channel Blockers; | 1995 |
Prospective evaluation of terazosin for the treatment of autonomic dysreflexia.
Topics: Adrenergic alpha-Agonists; Adult; Autonomic Nervous System Diseases; Humans; Male; Middle Aged; Praz | 1994 |
In vitro responses to noradrenaline of small intestine taken from normal and grass sickness-affected horses.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autonomic Nervous System Diseases; | 1997 |
[Induction of noradrenergic supersensitivity following cordotomy in neonatal rat spinal motoneurons].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Autonomic Nervou | 1999 |
Restoration of cardiac transient outward potassium current by norepinephrine in diabetic rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Nervous System Disease | 2000 |
[Several cardiovascular manifestations induced by vibrational stimuli].
Topics: Adult; Autonomic Nervous System Diseases; Cardiovascular Diseases; Fingers; Humans; Hypertension; Me | 1985 |
Postjunctional vascular smooth muscle alpha-2 adrenoreceptors in human autonomic failure.
Topics: Aged; Autonomic Nervous System Diseases; Blood Platelets; Blood Pressure; Clonidine; Dose-Response R | 1987 |