praziquantel has been researched along with Schistosoma mansoni Infection in 835 studies
azinox: Russian drug
| Excerpt | Relevance | Reference |
|---|---|---|
| "Schistosomiasis control relies on praziquantel for preventive chemotherapy." | 9.69 | SCHISTOACT: a protocol for an open-label, five-arm, non-inferiority, individually randomized controlled trial of the efficacy and safety of praziquantel plus artemisinin-based combinations in the treatment of Schistosoma mansoni infection. ( Muok, EMO; Obonyo, CO; Wamae, P; Were, VO, 2023) |
| "Praziquantel (PZQ) is the drug of choice for the treatment of all forms of schistosomiasis, although its mechanisms of action are not completely understood." | 9.22 | Praziquantel: An update on the mechanism of its action against schistosomiasis and new therapeutic perspectives. ( Carvalho, RC; Dos Santos, VAF; Filho, ACCM; Frazão, GCCG; Licá, ICL; Lira, MGS; Miranda, GS; Nascimento, FRF; Nogueira, RA; Rodrigues, JGM, 2022) |
| " We report Schistosoma mansoni infection levels in children one year after the initial school-based treatment (SBT) with praziquantel and compare with baseline results to determine the effect of the intervention." | 9.22 | Sustaining Control of Schistosomiasis Mansoni in Western Côte d'Ivoire: Results from a SCORE Study, One Year after Initial Praziquantel Administration. ( Assaré, RK; Coulibaly, JT; Hürlimann, E; Knopp, S; Meïté, A; N'Goran, EK; N'Guessan, NA; Ouattara, M; Tian-Bi, YN; Utzinger, J; Yao, PK; Yapi, A, 2016) |
| "To assess the efficacy and side effects of praziquantel in the treatment for Schistosoma mansoni infection in school children in Senbete Town, northeastern Ethiopia." | 9.17 | Efficacy and side effects of praziquantel in the treatment for Schistosoma mansoni infection in school children in Senbete Town, northeastern Ethiopia. ( Erko, B; Reta, B, 2013) |
| "com/ISRCTN32849447/elliott), offspring of women treated with praziquantel or placebo during pregnancy were examined for S." | 9.17 | Effect of maternal Schistosoma mansoni infection and praziquantel treatment during pregnancy on Schistosoma mansoni infection and immune responsiveness among offspring at age five years. ( Cose, S; Dunne, DW; Elliott, AM; Jones, FM; Mawa, PA; Naniima, P; Tweyongyere, R; Webb, EL, 2013) |
| " In addition, although mebendazole has been extensively used together with praziquantel against infections with schistosomiasis and soil-transmitted helminthiasis (STH) in school-aged children, no specific acceptability or safety studies have been published on this drug combination in younger children." | 9.15 | The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda. ( Kabatereine, NB; Namwanje, H; Olsen, A, 2011) |
| " Praziquantel treatment during pregnancy boosts maternal immune responses to schistosome antigens and reduces worm burden." | 9.15 | Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial. ( Cose, S; Dunne, DW; Elliott, AM; Jones, FM; Kihembo, M; Mawa, PA; Tweyongyere, R; Vennervald, BJ; Webb, EL, 2011) |
| "Praziquantel treatment of schistosomiasis during pregnancy was only recommended in 2002; hence the effects of treatment during pregnancy are not fully known." | 9.14 | Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection and antibody responses to schistosome antigens: results of a randomised, placebo-controlled trial. ( Dunne, DW; Duong, T; Elliott, AM; Emojong, NO; Jones, FM; Katunguka-Rwakishaya, E; Mawa, PA; Mpairwe, H; Tweyongyere, R; Vennervald, BJ, 2009) |
| "The objective of the present study was to test the hypothesis that treatment of schistosomiasis mansoni with praziquantel can alter significantly the immune response of patients and generate a reversal of the level of fibrosis." | 9.13 | Effect of chemotherapy with praziquantel on the production of cytokines and morbidity associated with schistosomiasis mansoni. ( Alves-Oliveira, LF; Correa-Oliveira, R; Gazzinelli, A; Gazzinelli, G; Malaquias, LC; Martins-Leite, P; Silveira, AM; Teixeira-Carvalho, A, 2008) |
| "Pregnancy suppresses a potentially beneficial boost in cytokine responses associated with praziquantel treatment." | 9.13 | Effect of praziquantel treatment during pregnancy on cytokine responses to schistosome antigens: results of a randomized, placebo-controlled trial. ( Dunne, DW; Duong, T; Elliott, AM; Katunguka-Rwakishaya, E; Mawa, PA; Ndibazza, J; Ngom-Wegi, S; Tweyongyere, R; Vennervald, BJ, 2008) |
| "To evaluate the therapeutic efficacy of oxamniquine and praziquantel, the two most clinically important schistosomicide drugs, and to compare the accuracy of faecal examination with the accuracy of oogram in testing for Schistosoma mansoni infection." | 9.10 | Efficacy of oxamniquine and praziquantel in the treatment of Schistosoma mansoni infection: a controlled trial. ( Antunes, CM; Coelho, PM; da Cunha, AS; Ferrari, ML; Tavares, CA, 2003) |
| "Two different regimens of praziquantel, 40 mg/kg in a single dose and 60 mg/kg in two divided doses administered 6 hr apart, for the treatment of Schistosoma mansoni infection were compared in Abu Homos, Egypt." | 9.08 | Praziquantel in the treatment of Schistosoma mansoni infection: comparison of 40 and 60 mg/kg bodyweight regimens. ( Abu-Elyazeed, RR; Cummings, CE; El-Gamal, RL; El-Khoby, TA; Hassanein, YA; Merrell, BR; Youssef, FG, 1997) |
| "In February 1987, 322 Sudanese school children were diagnosed for Schistosoma mansoni infection and treated randomly with praziquantel (either 20 mg/kg or 40 mg/kg body weight)." | 9.07 | Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity twenty-three months after treatment with praziquantel. ( Abdel-Rahim, IM; Doehring-Schwerdtfeger, E; Ehrich, JH; Elsheikh, M; Franke, D; Kaiser, C; Kardorff, R; Mohamed-Ali, Q; Richter, J; Schlake, J, 1992) |
| "Five hundred thirty six Sudanese schoolchildren with Schistosoma mansoni infection were treated at random with either 20 mg or 40 mg/kg praziquantel." | 9.07 | Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity seven months after treatment with praziquantel. ( Abdalla, M; Abdel-Rahim, IM; Doehring-Schwerdtfeger, E; Elsheikh, M; Franke, D; Kaiser, C; Kardorff, R; Mohamed-Ali, Q; Schafer, P; Schlake, J, 1991) |
| "Twenty-eight Zairean patients with Schistosoma mansoni infection were investigated and treated with praziquantel." | 9.06 | Re-infection in human schistosomiasis mansoni: a prospective field study 18 months after praziquantel therapy. ( Feldmeier, H; Harms, G; Müller, O; Poggensee, U; Steiner, A; Zwingenberger, K, 1990) |
| "A resurvey for schistosomiasis mansoni was carried out in a community 2 years after chemotherapy with praziquantel was stopped." | 9.06 | A three year follow-up of chemotherapy with praziquantel in a rural Zambian community endemic for schistosomiasis mansoni. ( Boatin, BA; Sukwa, TY; Wurapa, FK, 1988) |
| "Schistosomiasis is a widely distributed parasitic disease and one of the most important neglected tropical diseases globally, for which Praziquantel® (PZQ) is the only available treatment." | 8.12 | The Effect of Different Formulations of Praziquantel in Reducing Worms in the Prepatent Period of Schistosomiasis in Murine Models. ( da Silva, CH; de Moraes Neto, AHA; Leonardi, D; Mello Silva, CC; Paulino, ÉT; Real, DA; Ribeiro de Lima, M; Salomon, CJ; Viçosa, AL, 2022) |
| " The present study evaluated the effect of oral administration of five days celecoxib regimen (20 mg/kg/day) against different developmental stages of Schistosoma mansoni infection." | 8.02 | Effect of celecoxib against different developmental stages of experimental Schistosoma mansoni infection. ( Abou-El-Naga, IF; El-Temsahy, MM; Ibrahim, EI; Makled, S; Mogahed, NMFH; Sheta, E, 2021) |
| "In view of the potential immunosuppressive and regenerative properties of mesenchymal stem cells (MSC), we investigated whether transplantation of adipose tissue-derived stem cells (ASC) could be used to control the granulomatous reaction in the liver of mice infected with Schistosoma mansoni after Praziquantel (PZQ) treatment." | 7.96 | Liver damage in schistosomiasis is reduced by adipose tissue-derived stem cell therapy after praziquantel treatment. ( Alves, ÉAR; Bicalho, KA; Birbrair, A; Bozzi, A; Chaves, AT; Corrêa-Oliveira, R; de Goes, AM; Eller, DE; Ferraz, LCN; Gomes, TR; Miranda, VHS; Pascoal Xavier, MA; Silva, CEC, 2020) |
| " In this study, the biochemical effects of Schistosoma mansoni infection and praziquantel treatment were studied in 130 preschool aged and 159 school aged infected children and 11 noninfected children in Azaguié, Côte d'Ivoire." | 7.88 | Characterizing the Biochemical Response to Schistosoma mansoni Infection and Treatment with Praziquantel in Preschool and School Aged Children. ( Coulibaly, JT; Harvey, N; Keiser, J; Panic, G; Swann, J, 2018) |
| " Preliminary analyses of RNA sequencing revealed unique genes and canonical pathways associated with establishment of chronic disease, praziquantel-mediated parasite killing, and Sm-p80-mediated protection in vaccinated baboons." | 7.88 | Sm-p80-based vaccine trial in baboons: efficacy when mimicking natural conditions of chronic disease, praziquantel therapy, immunization, and Schistosoma mansoni re-encounter. ( Ahmad, G; Carey, D; Corstjens, PLAM; Freeborn, J; Ganapathy, PK; Hunter, D; Kim, E; Kottapalli, KR; Kottapalli, P; Molehin, AJ; Papin, JF; Redman, WK; Rojo, JU; Sennoune, SR; Siddiqui, AA; Siddiqui, AJ; Sudduth, J; Torben, W; van Dam, GJ; Wettashinghe, R; Zhang, W, 2018) |
| "A dual drug repurposing/nanotechnological approach was used to develop an alternative oral treatment for schistosomiasis mansoni using miltefosine (MFS), an anticancer alkylphosphocholine, and lipid nanocapsules (LNCs) as oral nanovectors." | 7.83 | Miltefosine lipid nanocapsules: Intersection of drug repurposing and nanotechnology for single dose oral treatment of pre-patent schistosomiasis mansoni. ( Eissa, MM; El-Azzouni, MZ; El-Khordagui, LK; El-Moslemany, RM; Ramadan, AA, 2016) |
| "A longitudinal study was conducted to evaluate the impact of praziquantel (PZQ) for the treatment of Schistosoma mansoni infection among schoolchildren in Al Gunaid in Central Sudan." | 7.78 | High levels of Schistosoma mansoni infections among schoolchildren in central Sudan one year after treatment with praziquantel. ( Adam, I; Ahmed, AM; El Tash, LA; Mohamed, EY, 2012) |
| " In this study we evaluated three methods used in the diagnosis of Schistosoma mansoni infection: parasitological (Kato-Katz), immunological (ELISA) and molecular (real time PCR), and also investigated the sensitivity of each technique in the cure determination after treatment with praziquantel using the water rat Nectomys squamipes, a natural reservoir for S." | 7.77 | Evaluation of immunological, parasitological and molecular methods for the diagnosis of Schistosoma mansoni infection before and after chemotherapy treatment with praziquantel in experimentally infected Nectomys squamipes. ( da Costa Neto, SF; da Costa, MM; Gentile, R; Gonçalves, MM; Peralta, JM; Peralta, RH, 2011) |
| "We sought to determine whether praziquantel reverses established pulmonary vascular remodeling and pulmonary hypertension in a mouse model of S." | 7.77 | Praziquantel reverses pulmonary hypertension and vascular remodeling in murine schistosomiasis. ( Butrous, G; Crosby, A; Dunne, DE; Jones, FM; Kolosionek, E; Morrell, NW; Purvis, I; Soon, E; Southwood, M, 2011) |
| "A serological assay was developed to assess the outcome of the treatment of intestinal schistosomiasis with praziquantel, in patients with Schistosoma mansoni infection." | 7.76 | Serological analysis of the outcome of treatment of Schistosoma mansoni infections with praziquantel. ( Bligh, J; Chiodini, PL; Doenhoff, MJ; Schramm, G, 2010) |
| "To investigate trends in the efficacy of praziquantel (PZQ) suggestive of the emergence of drug resistance against Schistosoma mansoni infection after 12." | 7.75 | Impact of intense, longitudinal retreatment with praziquantel on cure rates of schistosomiasis mansoni in a cohort of occupationally exposed adults in western Kenya. ( Black, CL; Colley, DG; Evan Secor, W; Karanja, DM; Mwinzi, PN; Steinauer, ML, 2009) |
| "The activity of lovastatin associated with oxamniquine or praziquantel against schistosomiasis mansoni was evaluated in mice infected with Schistosoma mansoni." | 7.74 | Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni. ( Araújo, N; Coelho, PM; Katz, N; Mattos, AC; Sarvel, AK, 2008) |
| "In a prospective study carried out in New Halfa Teaching Hospital, in eastern Sudan, between June 2001 and April 2003, 25 pregnant Sudanese women with schistosomiasis mansoni were each treated with a single oral dose of praziquantel (PZQ), at 40 mg/kg." | 7.73 | Praziquantel for the treatment of schistosomiasis mansoni during pregnancy. ( Adam, I; Elwasila, E; Homeida, M, 2005) |
| "This study is a trial to demonstrate the effect of the broad spectrum anthelmintic drug flubendazole (methyl 5-(p-fluoro-benzoyl)-2-benzimidazolecarbamate, CAS 31430-15-6), a mebendazole derivative, together with praziquantel (CAS 55268-74-1, EMBAY 8440, Biltricide) in murine schistosomiasis mansoni." | 7.72 | Effect of simultaneous and/or consecutive administration of the broad spectrum anthelmintic flubendazole together with praziquantel in experimental Schistosoma mansoni infection. ( Guirguis, F; Nessim, NG; William, S, 2003) |
| "The effect of treatment with praziquantel (PZQ) on the tegument of adult Schistosoma mansoni worms and on liver egg-granulomas has been examined in mice infected with PZQ-resistant and -susceptible parasite isolates." | 7.71 | Adult worm tegumental damage and egg-granulomas in praziquantel-resistant and -susceptible Schistosoma mansoni treated in vivo. ( Coles, GC; Dai, JR; Doenhoff, MJ; Liang, YS; Zhu, YC, 2002) |
| "This study was conducted to evaluate the efficacy of praziquantel (CAS 55268-74-1, EMBAY 8440, Biltricide) in different grades of Schistosoma mansoni infection." | 7.70 | Correlation between infection intensity, serum immunoglobulin profile, cellular immunity and the efficacy of treatment with praziquantel in murine schistosomiasis mansoni. ( Demerdash, Z; Nessim, NG, 2000) |
| "Colchicine treated mice showed significant decrease in prevalence of fibrocellular and fibrocellular and fibrous granulomas in liver specimens compared to corresponding control groups." | 7.69 | Histopathological evidences for the antifibrogenic effect of colchicine in schistosomiasis mansoni in mice. ( el-Monayerhy, MS; Fahmy, IA; Montasser, MF; Rashad, MS; Sabry, NM; Younis, TA, 1994) |
| " The effect of treatment with praziquantel at 8, 12, and 20 weeks postinfection on fibrosis was assessed by determination of total hepatic collagen content, ratio of type III/I + III collagen, granuloma volume, and histopathological examination of liver section." | 7.67 | Effect of praziquantel on hepatic fibrosis in experimental Schistosomiasis mansoni. ( Abdallah, NM; Botros, SS; el-Badrawy, NM; Hassanein, HI; Herbage, D; Nagy, FM, 1988) |
| "Selective treatment of Schistosoma mansoni infections in various endemic countries usually present cure rates of >70% when using the standard dose of 40 mg kg(-1) body weight of praziquantel." | 6.41 | Interpreting low praziquantel cure rates of Schistosoma mansoni infections in Senegal. ( Danso-Appiah, A; De Vlas, SJ, 2002) |
| "Human schistosomiasis is a neglected tropical disease caused by Schistosoma mansoni, S." | 5.91 | Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. ( Alwan, SN; LoVerde, PT; McHardy, SF; Rhodes, J; Taylor, AB; Tidwell, M, 2023) |
| "Curcumin-treated groups, with and without PZQ, resulted in higher significant Immunoreactivity score (IRS) for Bcl-2-associated X (BAX) and lower Interleukine- 17A (IL-17A), and Human epidermal growth factor (EGF), compared to the control." | 5.72 | Potentiality of curcumin on ISHAK scoring system and the expressions of BAX, IL-17A, and EGF in the treatment ofSchistosoma mansoni infection using Swiss albino mice. ( Abd-Elaal, AA; Amin, NM; El Saftawy, EA; El-Dardiry, MA; Negm, MSI, 2022) |
| "This study aimed to evaluate the efficacy of gamma-aminobutyric acid (GABA) alone or combined with praziquantel (PZQ) against Schistosoma (S) mansoni infection in a murine model." | 5.72 | Schistosomicidal and hepatoprotective activity of gamma-aminobutyric acid (GABA) alone or combined with praziquantel against Schistosoma mansoni infection in murine model. ( Fahmy, AM; Hegab, A; Tm, D; William, S, 2022) |
| "Schistosomiasis is one of the most devastating tropical diseases in the world." | 5.72 | Use of wogonin as a cooperative drug with praziquantel to better combat schistosomiasis. ( Cheng, PC; Hung, MY; Pekkle Lam, HY; Peng, SY, 2022) |
| "Praziquantel treatment of infected mice fed with a standard diet (IN-PZQ) resulted in a significant reduction of worm and egg burdens and a normalization of iron and calcium levels." | 5.72 | Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection. ( Abou-Bacar, A; Boukeng Jatsa, H; Brunet, J; Cannet, C; Gipwe Feussom, N; Greigert, V; Kadji Fassi, JB; Kamgang, R; Kamtchouing, P; Kenfack, CM; Membe Femoe, U; Pfaff, AW; Tchuem Tchuenté, LA; Tienga Nkondo, E, 2022) |
| "Plumbagin treatment restored hepatic enzymes activity to nearly normal levels and induced an increase in catalase, SOD, GSH, total thiol and GST in liver tissue homogenate." | 5.72 | Anti-inflammatory, antioxidant, anti-fibrotic and schistosomicidal properties of plumbagin in murine schistosomiasis. ( Abdel-Latif, M; Abuelsaad, ASA; Allam, GA; Bakery, HH; Elkenawy, AE; Khalil, RG, 2022) |
| "Lactoferrin is an 80 KDa iron-binding glycoprotein that plays a significant role in the innate immune system and is considered to be an important microbicide molecule." | 5.72 | Evaluation of faecal lactoferrin as a morbidity biomarker in Schistosoma mansoni infection. ( Abdo, S; Elhadad, H; Mohamed, MA; Mohamed, MM, 2022) |
| "Arpraziquantel, a first-line orodispersible tablet, showed high efficacy and favourable safety in preschool-aged children with schistosomiasis." | 5.69 | Efficacy, safety, and palatability of arpraziquantel (L-praziquantel) orodispersible tablets in children aged 3 months to 6 years infected with Schistosoma in Côte d'Ivoire and Kenya: an open-label, partly randomised, phase 3 trial. ( Aka, NAD; Assandé Aka, R; Badenhorst, H; Bagchus, WM; Bezuidenhout, D; Bödding, M; Dälken, B; Haj-Ali Saflo, O; Huber, E; Kourany-Lefoll, E; N'Goran, EK; Odiere, MR; Ogutu, B; Ouattara, M; Rawago, F; Tappert, A; Yin, X, 2023) |
| "Schistosomiasis control relies on praziquantel for preventive chemotherapy." | 5.69 | SCHISTOACT: a protocol for an open-label, five-arm, non-inferiority, individually randomized controlled trial of the efficacy and safety of praziquantel plus artemisinin-based combinations in the treatment of Schistosoma mansoni infection. ( Muok, EMO; Obonyo, CO; Wamae, P; Were, VO, 2023) |
| "Praziquantel treatment significantly reduced systemic OPN levels and liver collagen deposition, indicating that OPN could be a reliable tool for monitoring PZQ efficacy and fibrosis regression in murine schistosomiasis." | 5.62 | Praziquantel pharmacotherapy reduces systemic osteopontin levels and liver collagen content in murine schistosomiasis mansoni. ( Pereira, FEL; Pereira, TA; Souza, MM; Trindade Santos, E; Vaz de Melo Trindade, G, 2021) |
| "Praziquantel treatment (40 mg/kg) resulted in 96." | 5.51 | Schistosoma mansoni infection among preschool age children attending Erer Health Center, Ethiopia and the response rate to praziquantel. ( Abay, SM; Esmael, A; Kebede, T; Kemal, M; Tadesse, G, 2019) |
| "Schistosomiasis mansoni is considered one of the most common fibrotic diseases resulting from inflammation and deposition of fibrous tissue around parasitic eggs trapped in the liver, causing morbidity and mortality." | 5.48 | Impact of treatment with a Protein Tyrosine Kinase Inhibitor (Genistein) on acute and chronic experimental Schistosoma mansoni infection. ( El-Sayed, SH; Mahmoud, SS; Negm, MSI; Raafat, A; Rizk, EMA; Sobhy, MMK, 2018) |
| " This study focused on improving the biological characteristics of the already-existing antischistosomal praziquantel (PZQ) by incorporating it into montmorillonite (MMT) clay as a delivery carrier to overcome its known bioavailability drawbacks." | 5.42 | Praziquantel in a clay nanoformulation shows more bioavailability and higher efficacy against murine Schistosoma mansoni infection. ( Botros, SS; El-Feky, GS; El-Lakkany, NM; Mohamed, WS; Nasr, HE; Seif El-Din, SH, 2015) |
| " However, this treatment presents limitations such as low and/or erratic bioavailability that can contribute to cases of tolerance." | 5.42 | Effectiveness of hyperbaric oxygen for experimental treatment of schistosomiasis mansoni using praziquantel-free and encapsulated into liposomes: assay in adult worms and oviposition. ( Allegretti, SM; de Oliveira, CN; de Souza, AL; Dolder, MA; Frezza, TF; Giorgio, S; Gremião, MP; Joazeiro, PP; Prado, CC, 2015) |
| "Preventive chemotherapy using praziquantel is the mainstay for schistosomiasis control." | 5.41 | Effectiveness of school-based preventive chemotherapy strategies for sustaining the control of schistosomiasis in Côte d'Ivoire: Results of a 5-year cluster randomized trial. ( Assaré, RK; Bassa, FK; Coulibaly, JT; Diakité, NR; Guindo-Coulibaly, N; Hattendorf, J; Koné, N; N'Goran, EK; Ouattara, M; Saric, J; Utzinger, J; Yao, PK, 2021) |
| "Praziquantel chemotherapy has been the focus of the Schistosomiasis Control Program in Brazil for the past two decades." | 5.36 | Spatial distribution of Schistosoma mansoni infection before and after chemotherapy with two praziquantel doses in a community of Pernambuco, Brazil. ( Barbosa, CS; Carvalho, OS; Domingues, AL; Favre, TC; Felipe, KT; Galvão, AF; Guimarães, RJ; Pereira, AP; Pieri, OS; Zani, LC, 2010) |
| "G1b: treated with Praziquantel (PZQ) in a dose of 500 mg/kg for two consecutive days." | 5.35 | Parasitological and histo-pathological studies on schistosomiasis mansoni infected mice and treated with praziquatel and/or oltipraz. ( Morsy, GH, 2009) |
| " These effects were more pronounced with dosing regimens launched before the time of oviposition." | 5.32 | Activity of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine against Schistosomiasis mansoni in mice. ( Botros, S; Hammam, O; Holý, A; William, S; Zídek, Z, 2003) |
| "Treatment with praziquantel of individuals from the area residing temporarily in an urban region with no transmission, and re-treatment after 3 weeks of non-cured individuals within the area resulted in normal cure rates (78-88%)." | 5.31 | Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence. ( De Vlas, SJ; Diop, M; Engels, D; Faye, D; Gryseels, B; Guissé, F; Ly, A; Mbaye, A; Polman, K; Stelma, FF; Tchuem-Tchuenté, LA; Van Lieshout, L, 2001) |
| " mansoni infection on responses to childhood measles catch-up immunisation and of praziquantel treatment on this outcome in a randomised trial." | 5.30 | Effect of Schistosoma mansoni infection and its treatment on antibody responses to measles catch-up immunisation in pre-school children: A randomised trial. ( Cose, SC; Elliott, AM; Lule, SA; Muhwezi, A; Nassanga, BR; Nsubuga, RN; Odongo, M; Tweyongyere, R; Webb, EL, 2019) |
| "In praziquantel treated group the level of testosterone was lowered 10, 20 & 30 days post treatment, progesterone and 17 beta-estradiol fell 30 days post treatment after primary rise." | 5.29 | Effect of praziquantel on sex hormone levels in murine schistosomiasis mansoni. ( Abdalla, KF; Abdel-Aziz, SM; Afifi, LM; el Fakahany, AF; el-Hamshary, AS, 1994) |
| "Cimetidine was tested in doses of 50, 100 and 200 mg/kg for 2 consecutive days; praziquantel was given in doses of 100 and 500 mg/kg for 2 consecutive days." | 5.29 | Treatment of experimental schistosomiasis mansoni with praziquantel alone and combined with cimetidine. ( Bennet, JL; Botros, SS; Ebeid, FA; Metwally, AA, 1994) |
| "Treatment with Praziquantel resulted in substantial restoration of the production of 14CO2 from [14C]tryptophan." | 5.28 | Tryptophan metabolism and vitamin B6 nutritional status in patients with schistosomiasis mansoni and in infected mice. ( Bender, DA; Njagi, EN; Okelo, GB, 1992) |
| "In praziquantel-treated mice (500 mg/kg for 2 days orally), the reduction in the percent resistance (45." | 5.28 | Levamisole restored the compromised state of immunity after specific chemotherapy in experimental schistosomiasis mansoni. ( Azab, ME; Botros, SS; el-Garem, A; el-Nahal, HM; Hassan, SI; Shaker, ZA, 1989) |
| "Praziquantel (PZQ) is the drug of choice for the treatment of all forms of schistosomiasis, although its mechanisms of action are not completely understood." | 5.22 | Praziquantel: An update on the mechanism of its action against schistosomiasis and new therapeutic perspectives. ( Carvalho, RC; Dos Santos, VAF; Filho, ACCM; Frazão, GCCG; Licá, ICL; Lira, MGS; Miranda, GS; Nascimento, FRF; Nogueira, RA; Rodrigues, JGM, 2022) |
| " We report Schistosoma mansoni infection levels in children one year after the initial school-based treatment (SBT) with praziquantel and compare with baseline results to determine the effect of the intervention." | 5.22 | Sustaining Control of Schistosomiasis Mansoni in Western Côte d'Ivoire: Results from a SCORE Study, One Year after Initial Praziquantel Administration. ( Assaré, RK; Coulibaly, JT; Hürlimann, E; Knopp, S; Meïté, A; N'Goran, EK; N'Guessan, NA; Ouattara, M; Tian-Bi, YN; Utzinger, J; Yao, PK; Yapi, A, 2016) |
| "Sustaining high uptake of praziquantel is key for long-term control of schistosomiasis." | 5.20 | Reduced uptake of mass treatment for schistosomiasis control in absence of food: beyond a randomized trial. ( Katahoire, A; Muhumuza, S; Nuwaha, F; Olsen, A, 2015) |
| "To assess the efficacy and side effects of praziquantel in the treatment for Schistosoma mansoni infection in school children in Senbete Town, northeastern Ethiopia." | 5.17 | Efficacy and side effects of praziquantel in the treatment for Schistosoma mansoni infection in school children in Senbete Town, northeastern Ethiopia. ( Erko, B; Reta, B, 2013) |
| "com/ISRCTN32849447/elliott), offspring of women treated with praziquantel or placebo during pregnancy were examined for S." | 5.17 | Effect of maternal Schistosoma mansoni infection and praziquantel treatment during pregnancy on Schistosoma mansoni infection and immune responsiveness among offspring at age five years. ( Cose, S; Dunne, DW; Elliott, AM; Jones, FM; Mawa, PA; Naniima, P; Tweyongyere, R; Webb, EL, 2013) |
| " In addition, although mebendazole has been extensively used together with praziquantel against infections with schistosomiasis and soil-transmitted helminthiasis (STH) in school-aged children, no specific acceptability or safety studies have been published on this drug combination in younger children." | 5.15 | The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda. ( Kabatereine, NB; Namwanje, H; Olsen, A, 2011) |
| " Praziquantel treatment during pregnancy boosts maternal immune responses to schistosome antigens and reduces worm burden." | 5.15 | Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial. ( Cose, S; Dunne, DW; Elliott, AM; Jones, FM; Kihembo, M; Mawa, PA; Tweyongyere, R; Vennervald, BJ; Webb, EL, 2011) |
| "The efficacy and safety of oral artesunate+sulfadoxine/pyrimethamine (AS+SP) (4 mg/kg AS for 3 consecutive days+25 mg sulfadoxine on Day 0) in the treatment of Schistosoma mansoni infections were compared with those of praziquantel (PZQ) (40 mg/kg) among infected schoolchildren (46 in each study arm) in eastern Sudan." | 5.14 | Artesunate plus sulfadoxine/pyrimethamine versus praziquantel in the treatment of Schistosoma mansoni in eastern Sudan. ( Adam, I; Ahmed, Ael A; Eldein, WN; Gasim, GI; Magzoub, M; Mahgoub, HM; Mohamed, AA, 2009) |
| "Praziquantel treatment of schistosomiasis during pregnancy was only recommended in 2002; hence the effects of treatment during pregnancy are not fully known." | 5.14 | Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection and antibody responses to schistosome antigens: results of a randomised, placebo-controlled trial. ( Dunne, DW; Duong, T; Elliott, AM; Emojong, NO; Jones, FM; Katunguka-Rwakishaya, E; Mawa, PA; Mpairwe, H; Tweyongyere, R; Vennervald, BJ, 2009) |
| "The objective of the present study was to test the hypothesis that treatment of schistosomiasis mansoni with praziquantel can alter significantly the immune response of patients and generate a reversal of the level of fibrosis." | 5.13 | Effect of chemotherapy with praziquantel on the production of cytokines and morbidity associated with schistosomiasis mansoni. ( Alves-Oliveira, LF; Correa-Oliveira, R; Gazzinelli, A; Gazzinelli, G; Malaquias, LC; Martins-Leite, P; Silveira, AM; Teixeira-Carvalho, A, 2008) |
| "Pregnancy suppresses a potentially beneficial boost in cytokine responses associated with praziquantel treatment." | 5.13 | Effect of praziquantel treatment during pregnancy on cytokine responses to schistosome antigens: results of a randomized, placebo-controlled trial. ( Dunne, DW; Duong, T; Elliott, AM; Katunguka-Rwakishaya, E; Mawa, PA; Ndibazza, J; Ngom-Wegi, S; Tweyongyere, R; Vennervald, BJ, 2008) |
| "To evaluate the therapeutic efficacy of oxamniquine and praziquantel, the two most clinically important schistosomicide drugs, and to compare the accuracy of faecal examination with the accuracy of oogram in testing for Schistosoma mansoni infection." | 5.10 | Efficacy of oxamniquine and praziquantel in the treatment of Schistosoma mansoni infection: a controlled trial. ( Antunes, CM; Coelho, PM; da Cunha, AS; Ferrari, ML; Tavares, CA, 2003) |
| "Eighteen patients with acute Schistosoma mansoni infection were followed up for 2 years after treatment with praziquantel or oxamniquine." | 5.08 | Humoral immune responses in patients with acute Schistosoma mansoni infection who were followed up for two years after treatment. ( Garcia, MM; Katz, N; Pinto da Silva, RA; Rabello, AL; Rocha, RS, 1997) |
| "Two different regimens of praziquantel, 40 mg/kg in a single dose and 60 mg/kg in two divided doses administered 6 hr apart, for the treatment of Schistosoma mansoni infection were compared in Abu Homos, Egypt." | 5.08 | Praziquantel in the treatment of Schistosoma mansoni infection: comparison of 40 and 60 mg/kg bodyweight regimens. ( Abu-Elyazeed, RR; Cummings, CE; El-Gamal, RL; El-Khoby, TA; Hassanein, YA; Merrell, BR; Youssef, FG, 1997) |
| "The pharmacokinetics and therapeutic efficacy of praziquantel (Distocide; Epico, El-Asher-Men-Ramadan City, Egypt) were studied in 40 patients with schistosomiasis mansoni and various degrees of hepatic dysfunction." | 5.07 | Clinical and pharmacokinetic study of praziquantel in Egyptian schistosomiasis patients with and without liver cell failure. ( Abdel-Bary, MA; Abdel-Fatah, SA; el Guiniady, MA; el Touny, MA; Metwally, A, 1994) |
| "In February 1987, 322 Sudanese school children were diagnosed for Schistosoma mansoni infection and treated randomly with praziquantel (either 20 mg/kg or 40 mg/kg body weight)." | 5.07 | Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity twenty-three months after treatment with praziquantel. ( Abdel-Rahim, IM; Doehring-Schwerdtfeger, E; Ehrich, JH; Elsheikh, M; Franke, D; Kaiser, C; Kardorff, R; Mohamed-Ali, Q; Richter, J; Schlake, J, 1992) |
| "A comparison was made of the long-term impact of different methods of administration of chemotherapy (oxamniquine, 30 mg/kg in divided doses; or praziquantel, 40 mg/kg) on prevalence and intensity of Schistosoma mansoni infection in four areas in Kangundo Location, Machakos District, Kenya." | 5.07 | Comparison of different chemotherapy strategies against Schistosoma mansoni in Machakos District, Kenya: effects on human infection and morbidity. ( Butterworth, AE; Fulford, AJ; Kariuki, HC; Koech, D; Mbugua, GG; Ouma, JH; Sturrock, RF, 1991) |
| "Five hundred thirty six Sudanese schoolchildren with Schistosoma mansoni infection were treated at random with either 20 mg or 40 mg/kg praziquantel." | 5.07 | Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity seven months after treatment with praziquantel. ( Abdalla, M; Abdel-Rahim, IM; Doehring-Schwerdtfeger, E; Elsheikh, M; Franke, D; Kaiser, C; Kardorff, R; Mohamed-Ali, Q; Schafer, P; Schlake, J, 1991) |
| "Twenty-eight Zairean patients with Schistosoma mansoni infection were investigated and treated with praziquantel." | 5.06 | Re-infection in human schistosomiasis mansoni: a prospective field study 18 months after praziquantel therapy. ( Feldmeier, H; Harms, G; Müller, O; Poggensee, U; Steiner, A; Zwingenberger, K, 1990) |
| "A resurvey for schistosomiasis mansoni was carried out in a community 2 years after chemotherapy with praziquantel was stopped." | 5.06 | A three year follow-up of chemotherapy with praziquantel in a rural Zambian community endemic for schistosomiasis mansoni. ( Boatin, BA; Sukwa, TY; Wurapa, FK, 1988) |
| "Previous studies have reported that chemotherapy of schistosomiasis by praziquantel in humans boosts protective antibody responses against S mansoni and S haematobium." | 5.01 | Population level changes in schistosome-specific antibody levels following chemotherapy. ( Fukushige, M; Mutapi, F; Woolhouse, MEJ, 2019) |
| " This 'new' burden, inclusive of co-infections with Schistosoma haematobium and Schistosoma mansoni, is being formally explored as infected children are not presently targeted to receive praziquantel (PZQ) within current preventive chemotherapy campaigns." | 4.87 | Closing the praziquantel treatment gap: new steps in epidemiological monitoring and control of schistosomiasis in African infants and preschool-aged children. ( Amin, MA; Betson, M; Fenwick, A; Gabrielli, AF; Garba, A; Green, HK; Kabatereine, NB; Montresor, A; Mutapi, F; Mutumba-Nakalembe, M; Navaratnam, A; Sacko, M; Seto, EY; Sousa-Figueiredo, JC; Stothard, JR; Vaz Nery, S, 2011) |
| " Praziquantel and oxamniquine were effective in curing Schistosoma mansoni infection when compared to placebo." | 4.80 | Interventions for treating schistosomiasis mansoni. ( Atallah, A; Saconato, H, 2000) |
| " The evidence derives mainly from experiments on Schistosoma mansoni infections in the mouse with their immune status variously modulated; this review emphasises praziquantel (PZQ), which is now the main drug used for treatment of human schistosomiasis." | 4.78 | Immune-dependent chemotherapy of schistosomiasis. ( Cooper, RO; Doenhoff, MJ; Fallon, PG; Probert, AJ, 1992) |
| " Praziquantel, oxamniquine, hycanthone and antimony were less effective against Schistosoma mansoni infections in mice immunosuppressed by T cell-deprivation, than against comparable infections in normal mice." | 4.77 | The immune-dependence of chemotherapy in experimental schistosomiasis. ( Doenhoff, MJ, 1989) |
| " This study aimed to investigate baseline Schistosoma mansoni-Circulating Anodic Antigen (CAA) levels and their association with kidney biomarkers related to podocyte injury and inflammation in long-term follow-up after praziquantel (PZQ) treatment." | 4.31 | Subclinical signs of podocyte injury associated with Circulating Anodic Antigen (CAA) in Schistosoma mansoni-infected patients in Brazil. ( Bezerra, FSM; Corstjens, PLAM; Daher, EF; Dam, GJV; Galvão, RLF; Martins, AMC; Meneses, GC; Pinheiro, MCC; Sousa, MS, 2023) |
| "Mass drug administration of praziquantel becomes a less attractive strategy for elimination of schistosomiasis in low-prevalence areas due to cost implications and low treatment compliance." | 4.31 | Test-Treat-Track-Test-Treat Strategy for Control of Schistosomiasis in Two Low-Prevalence Villages in Northwestern Tanzania. ( Angelo, T; Campbell, CH; Kinung'hi, SM; Maganga, JK; Mosha, J; Mwanga, JR, 2023) |
| "Schistosomiasis is a widely distributed parasitic disease and one of the most important neglected tropical diseases globally, for which Praziquantel® (PZQ) is the only available treatment." | 4.12 | The Effect of Different Formulations of Praziquantel in Reducing Worms in the Prepatent Period of Schistosomiasis in Murine Models. ( da Silva, CH; de Moraes Neto, AHA; Leonardi, D; Mello Silva, CC; Paulino, ÉT; Real, DA; Ribeiro de Lima, M; Salomon, CJ; Viçosa, AL, 2022) |
| "Schistosomiasis control relies mainly on mass drug administration of Praziquantel (PZQ) to school aged children (SAC)." | 4.12 | Fine-scale mapping of Schistosoma mansoni infections and infection intensities in sub-districts of Makenene in the Centre region of Cameroon. ( Casacuberta-Partal, M; Kamdem, CN; Mbagnia, MCT; Mengoue, LET; Mewamba, EM; Njiokou, F; Simo, G; Tatang, RJA; Tchounkeu, EY; Tiofack, AAZ; Womeni, HM, 2022) |
| "Schistosomiasis is a major global health problem caused by blood-dwelling parasitic worms, which is currently tackled primarily by mass administration of the drug praziquantel." | 4.12 | Screening of a Library of Recombinant Schistosoma mansoni Proteins With Sera From Murine and Human Controlled Infections Identifies Early Serological Markers. ( Berriman, M; Brandt, C; Clare, S; Crosnier, C; Hokke, CH; Janse, JJ; Langenberg, MCC; Protasio, AV; Rinaldi, G; Roestenberg, M; Wilson, S; Wright, GJ, 2022) |
| " The present study evaluated the effect of oral administration of five days celecoxib regimen (20 mg/kg/day) against different developmental stages of Schistosoma mansoni infection." | 4.02 | Effect of celecoxib against different developmental stages of experimental Schistosoma mansoni infection. ( Abou-El-Naga, IF; El-Temsahy, MM; Ibrahim, EI; Makled, S; Mogahed, NMFH; Sheta, E, 2021) |
| " mansoni in PSAC in Assoni using double-stool smear preparation, (ii) treated the infected PSAC with a standard dose of praziquantel 40 mg/kg, (iii) ran educational campaigns each year in the village, and (iv) built latrines to improve sanitation and reduce schistosomiasis transmission." | 4.02 | A 12-year follow-up of intestinal schistosomiasis in pre-school-aged children in Assoni Village, Eastern Senegal. ( Barbier, D; Bessin, F; Danfakha, F; Dewavrin, P; Diawara, L; Diop, B; Keita, BF; Keita, F; Keita, G; Klotz, F; N'Diaye, M; Senghor, CS; Vernet, C, 2021) |
| " The effect of prolonged administration of bevacizumab with praziquantel was also assessed through parasitic load, protective index, granuloma and fibrous tissue evaluation." | 3.96 | Bevacizumab as a potential anti-angiogenic therapy in schistosomiasis: A double-edged, but adjustable weapon. ( El-Anwar, N; Hasby Saad, MA, 2020) |
| " Blood, urine and stool samples were collected from each participant to diagnose Schistosoma mansoni infection before and two times after treatment with praziquantel using serum- and urine based real-time PCR, point-of-care circulating cathodic antigen (POC-CCA) rapid diagnostic test and the microscopic Kato-Katz (KK) method." | 3.96 | Evaluation of serum-based real-time PCR to detect Schistosoma mansoni infection before and after treatment. ( Fuss, A; Mazigo, HD; Mueller, A, 2020) |
| "In view of the potential immunosuppressive and regenerative properties of mesenchymal stem cells (MSC), we investigated whether transplantation of adipose tissue-derived stem cells (ASC) could be used to control the granulomatous reaction in the liver of mice infected with Schistosoma mansoni after Praziquantel (PZQ) treatment." | 3.96 | Liver damage in schistosomiasis is reduced by adipose tissue-derived stem cell therapy after praziquantel treatment. ( Alves, ÉAR; Bicalho, KA; Birbrair, A; Bozzi, A; Chaves, AT; Corrêa-Oliveira, R; de Goes, AM; Eller, DE; Ferraz, LCN; Gomes, TR; Miranda, VHS; Pascoal Xavier, MA; Silva, CEC, 2020) |
| " The current study is to evaluate the performance of Paeoniflorin (PAE) as an anti-angiogenic therapy, being a powerful anti-fibrotic, compared to artemether (ART) and praziqantel (PZQ) in schistosomiasis mansoni BALB/c mice." | 3.91 | Paeoniflorin in experimental BALB/c mansoniasis: A novel anti-angiogenic therapy. ( Abd El-Aal, NF; Abdelbary, EH, 2019) |
| " In this study, the biochemical effects of Schistosoma mansoni infection and praziquantel treatment were studied in 130 preschool aged and 159 school aged infected children and 11 noninfected children in Azaguié, Côte d'Ivoire." | 3.88 | Characterizing the Biochemical Response to Schistosoma mansoni Infection and Treatment with Praziquantel in Preschool and School Aged Children. ( Coulibaly, JT; Harvey, N; Keiser, J; Panic, G; Swann, J, 2018) |
| " Preliminary analyses of RNA sequencing revealed unique genes and canonical pathways associated with establishment of chronic disease, praziquantel-mediated parasite killing, and Sm-p80-mediated protection in vaccinated baboons." | 3.88 | Sm-p80-based vaccine trial in baboons: efficacy when mimicking natural conditions of chronic disease, praziquantel therapy, immunization, and Schistosoma mansoni re-encounter. ( Ahmad, G; Carey, D; Corstjens, PLAM; Freeborn, J; Ganapathy, PK; Hunter, D; Kim, E; Kottapalli, KR; Kottapalli, P; Molehin, AJ; Papin, JF; Redman, WK; Rojo, JU; Sennoune, SR; Siddiqui, AA; Siddiqui, AJ; Sudduth, J; Torben, W; van Dam, GJ; Wettashinghe, R; Zhang, W, 2018) |
| "Praziquantel-based mass treatment is the main approach to controlling schistosomiasis mansoni in endemic areas." | 3.85 | Perceptions about interventions to control schistosomiasis among the Lake Victoria island communities of Koome, Uganda. ( Elliott, AM; Sanya, RE; Seeley, J; Tumwesige, E, 2017) |
| "A dual drug repurposing/nanotechnological approach was used to develop an alternative oral treatment for schistosomiasis mansoni using miltefosine (MFS), an anticancer alkylphosphocholine, and lipid nanocapsules (LNCs) as oral nanovectors." | 3.83 | Miltefosine lipid nanocapsules: Intersection of drug repurposing and nanotechnology for single dose oral treatment of pre-patent schistosomiasis mansoni. ( Eissa, MM; El-Azzouni, MZ; El-Khordagui, LK; El-Moslemany, RM; Ramadan, AA, 2016) |
| "Here we analyse epidemiological data from three West African countries co-endemic for urogenital and intestinal schistosomiasis (Senegal, Niger and Mali) to test whether the impact of praziquantel (PZQ) treatment, subsequent levels of re-infection or long-term infection dynamics are altered by co-infection." | 3.81 | Epidemiological Interactions between Urogenital and Intestinal Human Schistosomiasis in the Context of Praziquantel Treatment across Three West African Countries. ( Diaw, OT; Fenwick, A; Garba, A; Knowles, SC; Rollinson, D; Sacko, M; Webster, BL; Webster, JP, 2015) |
| "Currently, praziquantel is the drug of choice for the treatment of human Schistosoma mansoni infections." | 3.80 | Dihydroartemisinin: a new story of an old drug against Schistosoma mansoni infection. ( Li, HJ; Wang, W; Wang, YH; Xu, FL; Yi, ZJ, 2014) |
| " This study was conducted to assess whether the short form of the World Health Organization (WHO) QOL questionnaire (WHOQOL-BREF) was an effective tool for measuring morbidity due to Schistosoma mansoni infection and whether it could detect an impact of treatment with praziquantel." | 3.80 | Assessment of quality of life as a tool for measuring morbidity due to Schistosoma mansoni infection and the impact of treatment. ( Abudho, B; Blackstock, AJ; Foo, KT; Hightower, AW; Karanja, DM; Kennedy, ED; Montgomery, SP; Mwinzi, PN; Ochola, EA; Person, B; Secor, WE; Won, KY, 2014) |
| "This study aims to evaluate the immunomodulatory effects of a natural product, blue green algae (BGA) (100 mg/kg BW), alone or combined with praziquantel PZQ (250 mg/kg BW) on granulomatous inflammation, liver histopathology, some biochemical and immunological parameters in mice infected with Schistosoma mansoni." | 3.80 | The hepatoprotective activity of blue green algae in Schistosoma mansoni infected mice. ( Elmalawany, AM; Mohamed, AH; Osman, GY; Salem, TA, 2014) |
| " Treatment of infected mice with Pps, although failed to eradicate the worm, significantly reduced the hepatic granuloma number, their lymphocytic infiltration and aggregation, hepatic and splenic myeloperoxidase (MPO) activity and plasma, and liver and thymus nitric oxide (NOx) levels together with normalization of plasma proteins and alleviation of oxidative stress in the examined tissues as evidenced by reduction of malondialdehyde (MDA) and normalization of glutathione (GSH)." | 3.80 | Propolis enhances the effectiveness of praziquantel in experimental schistosomiasis: biochemical and histopathological study. ( Maghraby, AS; Mahmoud, TY; Rizk, SM; Shaheen, AA, 2014) |
| "Currently, schistosomiasis mansoni is treated clinically with praziquantel (PZQ)." | 3.79 | Liposomal-praziquantel: efficacy against Schistosoma mansoni in a preclinical assay. ( Allegretti, SM; de Souza, AL; Frezza, TF; Gremião, MP; Magalhães, LA; Zanotti-Magalhães, EM, 2013) |
| "The present study evaluated the use of 3 types of Cysteine Protease Inhibitors (CPIs) with praziquantel (PZQ) as chemotherapy against schistosomiasis mansoni in mice." | 3.79 | Overview on cysteine protease inhibitors as chemotherapy for Schistosomiasis mansoni in mice and also its effect on the parasitological and immunological profile. ( El Amir, AM; Farid, A; Helmy, A; Malek, AA; Rabie, I, 2013) |
| "A longitudinal study was conducted to evaluate the impact of praziquantel (PZQ) for the treatment of Schistosoma mansoni infection among schoolchildren in Al Gunaid in Central Sudan." | 3.78 | High levels of Schistosoma mansoni infections among schoolchildren in central Sudan one year after treatment with praziquantel. ( Adam, I; Ahmed, AM; El Tash, LA; Mohamed, EY, 2012) |
| "Schistosomiasis, a high volume neglected tropical disease affecting more than 200 million people worldwide, can only be effectively treated by the tetrahydroisoquinoline drug praziquantel (PZQ)." | 3.78 | MCR synthesis of praziquantel derivatives. ( Botros, S; Dömling, A; Herdtweck, E; Liu, H; William, S, 2012) |
| " In this study we evaluated three methods used in the diagnosis of Schistosoma mansoni infection: parasitological (Kato-Katz), immunological (ELISA) and molecular (real time PCR), and also investigated the sensitivity of each technique in the cure determination after treatment with praziquantel using the water rat Nectomys squamipes, a natural reservoir for S." | 3.77 | Evaluation of immunological, parasitological and molecular methods for the diagnosis of Schistosoma mansoni infection before and after chemotherapy treatment with praziquantel in experimentally infected Nectomys squamipes. ( da Costa Neto, SF; da Costa, MM; Gentile, R; Gonçalves, MM; Peralta, JM; Peralta, RH, 2011) |
| "We sought to determine whether praziquantel reverses established pulmonary vascular remodeling and pulmonary hypertension in a mouse model of S." | 3.77 | Praziquantel reverses pulmonary hypertension and vascular remodeling in murine schistosomiasis. ( Butrous, G; Crosby, A; Dunne, DE; Jones, FM; Kolosionek, E; Morrell, NW; Purvis, I; Soon, E; Southwood, M, 2011) |
| "A serological assay was developed to assess the outcome of the treatment of intestinal schistosomiasis with praziquantel, in patients with Schistosoma mansoni infection." | 3.76 | Serological analysis of the outcome of treatment of Schistosoma mansoni infections with praziquantel. ( Bligh, J; Chiodini, PL; Doenhoff, MJ; Schramm, G, 2010) |
| " However, the optimal time points post-treatment for assessing the efficacy of praziquantel against Schistosoma mansoni and albendazole against hookworm infections are not known." | 3.75 | Sequential analysis of helminth egg output in human stool samples following albendazole and praziquantel administration. ( Allangba, A; Lohourignon, LK; N'Goran, EK; Scherrer, AU; Sjöberg, MK; Traoré, M; Tschannen, AB; Utzinger, J, 2009) |
| "To investigate trends in the efficacy of praziquantel (PZQ) suggestive of the emergence of drug resistance against Schistosoma mansoni infection after 12." | 3.75 | Impact of intense, longitudinal retreatment with praziquantel on cure rates of schistosomiasis mansoni in a cohort of occupationally exposed adults in western Kenya. ( Black, CL; Colley, DG; Evan Secor, W; Karanja, DM; Mwinzi, PN; Steinauer, ML, 2009) |
| "The activity of lovastatin associated with oxamniquine or praziquantel against schistosomiasis mansoni was evaluated in mice infected with Schistosoma mansoni." | 3.74 | Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni. ( Araújo, N; Coelho, PM; Katz, N; Mattos, AC; Sarvel, AK, 2008) |
| "In a prospective study carried out in New Halfa Teaching Hospital, in eastern Sudan, between June 2001 and April 2003, 25 pregnant Sudanese women with schistosomiasis mansoni were each treated with a single oral dose of praziquantel (PZQ), at 40 mg/kg." | 3.73 | Praziquantel for the treatment of schistosomiasis mansoni during pregnancy. ( Adam, I; Elwasila, E; Homeida, M, 2005) |
| "This study is a trial to demonstrate the effect of the broad spectrum anthelmintic drug flubendazole (methyl 5-(p-fluoro-benzoyl)-2-benzimidazolecarbamate, CAS 31430-15-6), a mebendazole derivative, together with praziquantel (CAS 55268-74-1, EMBAY 8440, Biltricide) in murine schistosomiasis mansoni." | 3.72 | Effect of simultaneous and/or consecutive administration of the broad spectrum anthelmintic flubendazole together with praziquantel in experimental Schistosoma mansoni infection. ( Guirguis, F; Nessim, NG; William, S, 2003) |
| "Currently, schistosomiasis control in Mali is mainly based on treatment with praziquantel (PZQ)." | 3.72 | Evaluation of case management in the integrated schistosomiasis-control programme in Mali. ( de Vlas, SJ; Landouré, A; Traoré, M; van der Werf, MJ, 2003) |
| "To determine the relative susceptibility of Schistosoma mansoni infections to treatment with the oxamniquine (OXA) and praziquantel (PZQ)." | 3.71 | Efficacy of oxamniquine and praziquantel in school children from two Schistosoma mansoni endemic areas. ( Mbugua, GG; Ouma, JH; Sturrock, RK; Thiong'o, FW, 2002) |
| "The effect of treatment with praziquantel (PZQ) on the tegument of adult Schistosoma mansoni worms and on liver egg-granulomas has been examined in mice infected with PZQ-resistant and -susceptible parasite isolates." | 3.71 | Adult worm tegumental damage and egg-granulomas in praziquantel-resistant and -susceptible Schistosoma mansoni treated in vivo. ( Coles, GC; Dai, JR; Doenhoff, MJ; Liang, YS; Zhu, YC, 2002) |
| "In a fishing community on Lake Albert in Uganda the pattern of intensity of Schistosoma mansoni infection 6 months after treatment with praziquantel was found to be very similar to reinfection patterns seen in previously studied endemic communities: the profile peaks sharply at around the age of 10 years falling away rapidly to much lower levels in adults." | 3.70 | Adult resistance to schistosomiasis mansoni: age-dependence of reinfection remains constant in communities with diverse exposure patterns. ( Butterworth, AE; Dunne, DW; Fulford, AJ; Kabatereine, NB; Kemijumbi, J; Ouma, JH; Vennervald, BJ, 1999) |
| "Treatment with praziquantel reduces the prevalence and intensity of Schistosoma mansoni infection." | 3.70 | Evidence for a long-term effect of a single dose of praziquantel on Schistosoma mansoni-induced hepatosplenic lesions in northern Uganda. ( Doehring, E; Frenzel, K; Grigull, L; Loroni-Lakwo, T; Ndugwa, CM; Odongo-Aginya, E; Schweigmann, U; Spannbrucker, N; Vester, U, 1999) |
| "This study was conducted to evaluate the efficacy of praziquantel (CAS 55268-74-1, EMBAY 8440, Biltricide) in different grades of Schistosoma mansoni infection." | 3.70 | Correlation between infection intensity, serum immunoglobulin profile, cellular immunity and the efficacy of treatment with praziquantel in murine schistosomiasis mansoni. ( Demerdash, Z; Nessim, NG, 2000) |
| "This study was done to assess the use of immune complexes estimated by micro-ELISA as monitors of cure of schistosomiasis mansoni experimentally infected Swiss albino mice which received praziquantel (PZQ) treatment." | 3.69 | Immune complexes as monitors of cure in Schistosoma mansoni infected mice. ( Abdallah, HM; Bebars, MA; el Zayyat, EA; Ismail, MS; Khalil, HM; Khalil, NM, 1995) |
| "Schistosoma mansoni infections in mice were treated with subcurative multiple doses of either praziquantel (PZQ) or oxamniquine (OX)." | 3.69 | Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific. ( Doenhoff, MJ; Fallon, PG, 1994) |
| "Colchicine treated mice showed significant decrease in prevalence of fibrocellular and fibrocellular and fibrous granulomas in liver specimens compared to corresponding control groups." | 3.69 | Histopathological evidences for the antifibrogenic effect of colchicine in schistosomiasis mansoni in mice. ( el-Monayerhy, MS; Fahmy, IA; Montasser, MF; Rashad, MS; Sabry, NM; Younis, TA, 1994) |
| "In infected mice, pyridinoline increased mainly in the isolated granulomas, corresponding to the fibrotic lesions, and slightly in the surrounding parenchyma." | 3.69 | Urinary excretion of the collagen cross-link pyridinoline increases during liver fibrogenesis. ( Blanquier, B; Grenard, P; Ricard-Blum, S, 1997) |
| "Non steroidal anti-inflammatory drugs (NSAIDs) (tiaprofenic acid and piroxicam have been used alone and as adjuvants to praziquantel in treating hepatic granuloma in Schistosoma mansoni infected mice." | 3.69 | Comparative effect of tiaprofenic acid and piroxicam alone and as adjuvants to praziquantel in Schistosoma mansoni infected mice. ( Hegazy, IH; Moussa, SM; Nassar, SH, 1997) |
| " The efficacy of BAPN, alone or in association with the anti-schistosomal drug, praziquantel (PZQ), was primarily assessed by measuring the reduction in liver and intestinal egg loads in murine schistosomiasis mansoni." | 3.68 | Experimental schistosomiasis mansoni: modulation of granulomas by inhibition of collagen cross-link formation. Preliminary report. ( Giboda, M; Julis, I; Vítovec, J; Zenka, J, 1992) |
| "This study examines the immune-dependence of praziquantel (PZQ) for the treatment of Schistosomiasis mansoni in mice." | 3.68 | Immune dependence of schistosomicidal chemotherapy: an ultrastructural study of Schistosoma mansoni adult worms exposed to praziquantel and immune serum in vivo. ( Doenhoff, MJ; Lambertucci, JR; McLaren, DJ; Modha, J, 1990) |
| "Peripheral blood T cell phenotypes, CD3-induced mitogenesis and soluble IL 2 receptor and CD8 in sera were studied in intestinal and hepatosplenic Schistosomiasis mansoni before and three to six months after therapy with praziquantel." | 3.67 | T cell phenotype alterations in hepatosplenic schistosomiasis mansoni normalize after chemotherapy. ( Bienzle, U; Correia Dacal, AR; Feldmeier, H; Harms, G; Jansen-Rosseck, R; Vergetti de Siqueira, JG; Zwingenberger, K, 1989) |
| "The cellular and humoral immune responses of CF1 and C57BL/6 mice with schistosomiasis mansoni were evaluated before and after chemotherapeutic cure of their infections by praziquantel." | 3.67 | Effects of anti-schistosomal chemotherapy on immune responses, protection and immunity. I. Changes in cellular and humoral responses. ( Carter, CE; Colley, DG; Tawfik, AF, 1986) |
| " The effect of treatment with praziquantel at 8, 12, and 20 weeks postinfection on fibrosis was assessed by determination of total hepatic collagen content, ratio of type III/I + III collagen, granuloma volume, and histopathological examination of liver section." | 3.67 | Effect of praziquantel on hepatic fibrosis in experimental Schistosomiasis mansoni. ( Abdallah, NM; Botros, SS; el-Badrawy, NM; Hassanein, HI; Herbage, D; Nagy, FM, 1988) |
| "Effective schistosomicidal action of praziquantel against Schistosoma mansoni infections in mice appears to be dependent to some extent on appropriate immunological stimulation." | 3.67 | Evidence for an immune-dependent action of praziquantel on Schistosoma mansoni in mice. ( Bain, J; Doenhoff, MJ; Fletcher, C; Sabah, AA; Webbe, G, 1987) |
| "We evaluated praziquantel for therapy of active Schistosoma mansoni infection in 15 rural Egyptian males with hepatosplenic schistosomiasis." | 3.67 | Praziquantel for treatment of schistosomiasis in patients with advanced hepatosplenomegaly. ( Bassily, S; Dunn, M; el-Masry, NA; Farid, Z; Stek, M, 1985) |
| "Praziquantel (PZQ) has been extensively used as the drug of choice for the treatment of schistosomiasis on account of its safety and effectiveness against all major forms of schistosomiasis." | 3.01 | Praziquantel efficacy, urinary and intestinal schistosomiasis reinfection - a systematic review. ( Aboagye, IF; Addison, YAA, 2023) |
| " Adverse events were assessed within four hours of drugs intake." | 2.94 | Efficacy and safety of praziquantel and dihydroartemisinin piperaquine combination for treatment and control of intestinal schistosomiasis: A randomized, non-inferiority clinical trial. ( Aklillu, E; Kamuhabwa, A; Kinung'hi, S; Minzi, O; Mnkugwe, RH, 2020) |
| "Praziquantel treatment was not linked to a major shift in the gut taxonomic profiles, thus reinforcing the good safety profile of the drug by ruling out off-targets effects on the gut microbes." | 2.87 | Investigations on the interplays between Schistosoma mansoni, praziquantel and the gut microbiome. ( Coulibaly, JT; Daubenberger, C; Frey, JE; Gueuning, M; Keiser, J; Panic, G; Schneeberger, PHH, 2018) |
| "Praziquantel has been the drug of choice for schistosomiasis control for more than 40 years, yet surprisingly, the optimal dose for children younger than 4 years is not known." | 2.84 | Efficacy and safety of praziquantel in preschool-aged and school-aged children infected with Schistosoma mansoni: a randomised controlled, parallel-group, dose-ranging, phase 2 trial. ( Coulibaly, JT; Hattendorf, J; Keiser, J; Kovač, J; Panic, G; Silué, KD, 2017) |
| "Praziquantel was distributed by school teachers to students either annually, the first 2 years, or every other year over a 4 year period." | 2.84 | Cluster randomized trial comparing school-based mass drug administration schedules in areas of western Kenya with moderate initial prevalence of Schistosoma mansoni infections. ( Abudho, BO; Awino, EK; Karanja, DMS; Montgomery, SP; Mwinzi, PNM; Okoth, E; Secor, WE; Wiegand, RE, 2017) |
| "Schistosomiasis is a poverty-associated tropical disease caused by blood dwelling trematodes that threaten approximately 10% of the world population." | 2.82 | Improving translational power in antischistosomal drug discovery. ( Biendl, S; Keiser, J; Probst, A, 2022) |
| "Arachidonic acid (ARA), an omega-6 fatty acid, is a potent schistosomicide that displayed significant and safe therapeutic effects in Schistosoma mansoni-infected schoolchildren in S." | 2.80 | Efficacy and safety of arachidonic acid for treatment of school-age children in Schistosoma mansoni high-endemicity regions. ( Abou El-Ela, NE; Barakat, R; Bruins, MJ; El Ridi, R; El Sagheer, O; Hadley, KB; Selim, S; Sharaf, S; Tallima, H, 2015) |
| "Schistosoma mansoni infection is proven to be a major health problem of preschool-age children in sub-Saharan Africa, yet this age category is not part of the schistosomiasis control program." | 2.80 | Single Versus Double Dose Praziquantel Comparison on Efficacy and Schistosoma mansoni Re-Infection in Preschool-Age Children in Uganda: A Randomized Controlled Trial. ( Nalugwa, A; Nuwaha, F; Olsen, A; Tukahebwa, EM, 2015) |
| "Arachidonic acid (ARA), an omega-6 fatty acid, kills juvenile and adult schistosomes in vitro and displays highly significant and safe therapeutic effects in mice and hamsters infected with Schistosoma mansoni or S." | 2.79 | Efficacy and safety of arachidonic acid for treatment of Schistosoma mansoni-infected children in Menoufiya, Egypt. ( Barakat, R; Bruins, MJ; El Amir, A; El Ridi, R; El Sagheer, O; Hadley, K; Selim, S, 2014) |
| "Diagnosis of intestinal schistosomiasis was assessed using single stool sample, double Kato-Katz smear examinations." | 2.77 | Efficacy of praziquantel syrup versus crushed praziquantel tablets in the treatment of intestinal schistosomiasis in Ugandan preschool children, with observation on compliance and safety. ( Fenwick, A; Kabatereine, NB; Mutumba-Nakalembe, MJ; Navaratnam, AM; Sousa-Figueiredo, JC; Stothard, JR, 2012) |
| " Separately, a previously tested side-effect questionnaire was employed before and 24 hours after PZQ treatment to assess incidence and amelioration of symptoms in young children and their mothers." | 2.77 | Performance and safety of praziquantel for treatment of intestinal schistosomiasis in infants and preschool children. ( Arinaitwe, M; Atuhaire, A; Betson, M; Bickle, Q; Kabatereine, NB; Navaratnam, AM; Sousa-Figueiredo, JC; Stothard, JR, 2012) |
| " 666 patients (78%) reported 1327 adverse events (AE) 4 h post-dosing." | 2.76 | A multicentre randomized controlled trial of the efficacy and safety of single-dose praziquantel at 40 mg/kg vs. 60 mg/kg for treating intestinal schistosomiasis in the Philippines, Mauritania, Tanzania and Brazil. ( Alves, F; Amarillo, ML; Belizario, VJ; Chitsulo, L; Diaw, M; Domingues, AC; Favre, TC; Kaatano, GM; Lapujade, O; Lwambo, NJ; Olliaro, PL; Ouldabdallahi, M; Pieri, OS; Vaillant, MT, 2011) |
| "Schistosomiasis is a parasitic infection that commonly affects the gastrointestinal and genitourinary tracts." | 2.72 | Surgical management outcome of cerebral schistosomiasis: a case report and review of the literature. ( Ahmed, MMZ; Ginawi, A; Mohamed, AHA; Osman, HHM, 2021) |
| "Praziquantel cure rate was 73." | 2.71 | Efficacy of myrrh in the treatment of human Schistosomiasis mansoni. ( Barakat, R; Elmorshedy, H; Fenwick, A, 2005) |
| " Statistical analysis of the pharmacokinetic parameters of brand 1 vs brand 2 (in a dose of 20 or 40 mg kg-1) revealed no significant difference in elimination (ke), absorption rate constant (ka), elimination half life (t1/2e), area under the time-concentration curve (Auc), serum maximum concentration (Cpmax) and time to maximum concentration (Tmax)." | 2.68 | Impact of drug dosage and brand on bioavailability and efficacy of praziquantel. ( Bennett, J; Botros, S; Ebeid, F; el attar, Gel D; Metwally, A, 1995) |
| " mansoni focus in northern Senegal, following treatment with a standard dosage of 40 mg/kg." | 2.68 | Therapeutic evaluation of two different dose regimens of praziquantel in a recent Schistosoma mansoni focus in Northern Senegal. ( Deelder, AM; Gryseels, B; Guisse, F; Mbaye, A; Ndir, O; Niang, M; Polman, K; Stelma, FF; Talla, I, 1997) |
| "We evaluated the quantitation of two schistosome circulating antigens in serum and urine as a tool for the assessment of the efficacy of praziquantel dosage regimens (40 versus 60 mg/kgbw)." | 2.67 | Monitoring the efficacy of different doses of praziquantel by quantification of circulating antigens in serum and urine of schistosomiasis patients. ( Bassily, S; de Jonge, N; Deelder, AM; el-Masry, N; Krijger, FW; Mansour, MM; van Lieshout, L, 1994) |
| " Surveillance for praziquantel adverse reactions for all these groups was done." | 2.67 | Side effects of praziquantel in bilharzial children on a field level. ( el-Hawey, AM; el-Rakieby, A; Massoud, AM; Nassar, MO; Rozeik, MS, 1990) |
| " Safety was summarized using reported adverse events (AEs)." | 2.66 | Efficacy and safety of single-dose 40 mg/kg oral praziquantel in the treatment of schistosomiasis in preschool-age versus school-age children: An individual participant data meta-analysis. ( Coulibaly, JT; Garba, A; Halleux, C; Keiser, J; King, CH; Mutapi, F; N'Goran, EK; Olliaro, PL; Raso, G; Scherrer, AU; Sousa-Figueiredo, JC; Stete, K; Utzinger, J; Vaillant, MT, 2020) |
| "praziquantel was equally effective against both parasite species." | 2.66 | The effect of metrifonate in mixed Schistosoma haematobium and Schistosoma mansoni infections in humans. ( Doehring, E; Feldmeier, H; Poggensee, U, 1986) |
| "Further research will help find the optimal dosing regimen of both these drugs in children." | 2.49 | Drugs for treating Schistosoma mansoni infection. ( Danso-Appiah, A; Donegan, S; Olliaro, PL; Sinclair, D; Utzinger, J, 2013) |
| "Treatment with praziquantel the drug of choice in Uganda used in schistosomiasis control programme has reduced development of severe schistosomiasis." | 2.44 | Epidemiology, of bilharzias (schistosomiasis) in Uganda from 1902 until 2005. ( Ekkehard, D; Emmanuel, IO, 2008) |
| "However, liver fibrosis is reversible if antischistosomal drugs are administered before the onset of severe hepatic insufficiency." | 2.41 | [Schistosoma mansoni schistosomiasis]. ( Dessein, A; Ranque, S, 2001) |
| "Selective treatment of Schistosoma mansoni infections in various endemic countries usually present cure rates of >70% when using the standard dose of 40 mg kg(-1) body weight of praziquantel." | 2.41 | Interpreting low praziquantel cure rates of Schistosoma mansoni infections in Senegal. ( Danso-Appiah, A; De Vlas, SJ, 2002) |
| "We report a case of acute transverse myelitis due to Schistosoma mansoni in which treatment with praziquantal and steroids was started three days after the onset of a paraparesis, with complete neurological recovery." | 2.37 | Spinal cord schistosomiasis: a case report and review of the literature. ( Doodha, M; Horwitz, T; Klein, C; Lalla, S; Suchet, I, 1987) |
| " leaves (MOL) alone or in combination with praziquantel (PZQ) drug targeting-infected mice with Schistosoma mansoni-induced liver and spleen damage." | 1.91 | Parasitological and histopathological studies to the effect of aqueous extract of Moringa oleifera Lam. leaves combined with praziquantel therapy in modulating the liver and spleen damage induced by Schistosoma mansoni to male mice. ( Elrayess, RA; Gad El-Hak, HN; Ghobashy, MA; Saad El-Din, MI, 2023) |
| "Schistosomiasis is a neglected tropical disease and a serious global-health problem with over 230 million people requiring treatment, of which the majority live in Africa." | 1.91 | Understanding perceptions of schistosomiasis and its control among highly endemic lakeshore communities in Mayuge, Uganda. ( Lamberton, PHL; Meginnis, K; Mujumbusi, L; Nalwadda, E; Pickering, L; Seeley, J; Ssali, A, 2023) |
| "Schistosomiasis is one of the most prevalent helminthic infections worldwide." | 1.91 | Anti-angiogenic and anti-proliferative activity of ziziphus leaf extract as a novel potential therapeutic agent for reducing hepatic injury in experimental hamster schistosomiasis. ( Alghamdi, T; El-Refaei, MF; Salem, DA, 2023) |
| "Human schistosomiasis is a neglected tropical disease caused by Schistosoma mansoni, S." | 1.91 | Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. ( Alwan, SN; LoVerde, PT; McHardy, SF; Rhodes, J; Taylor, AB; Tidwell, M, 2023) |
| "Schistosomiasis is the second most prevailing parasitic disease worldwide." | 1.91 | In vitro and In silico assessment of antischistosomal activities of ethanolic extract of Cornulacamonacantha. ( Abdel-Malek, AR; Abdelrady, YA; Ali, MF; Anwar, FS; Farouk, M; Salem, SH; Sayed, AM, 2023) |
| "The goal for schistosomiasis is to achieve elimination as a public health problem (EPHP) and elimination of transmission (EOT) in 78 and 25 countries (by 2030), respectively." | 1.72 | Determining the optimal strategies to achieve elimination of transmission for Schistosoma mansoni. ( Anderson, RM; Ayabina, D; Hollingsworth, TD; Kura, K, 2022) |
| "Curcumin-treated groups, with and without PZQ, resulted in higher significant Immunoreactivity score (IRS) for Bcl-2-associated X (BAX) and lower Interleukine- 17A (IL-17A), and Human epidermal growth factor (EGF), compared to the control." | 1.72 | Potentiality of curcumin on ISHAK scoring system and the expressions of BAX, IL-17A, and EGF in the treatment ofSchistosoma mansoni infection using Swiss albino mice. ( Abd-Elaal, AA; Amin, NM; El Saftawy, EA; El-Dardiry, MA; Negm, MSI, 2022) |
| "This study aimed to evaluate the efficacy of gamma-aminobutyric acid (GABA) alone or combined with praziquantel (PZQ) against Schistosoma (S) mansoni infection in a murine model." | 1.72 | Schistosomicidal and hepatoprotective activity of gamma-aminobutyric acid (GABA) alone or combined with praziquantel against Schistosoma mansoni infection in murine model. ( Fahmy, AM; Hegab, A; Tm, D; William, S, 2022) |
| "Schistosomiasis mansoni is considered a serious public health problem." | 1.72 | The prophylactic and anti-fibrotic activity of phthalimido-thiazole derivatives in schistosomiasis mansoni. ( Araújo, DL; de Araújo, RE; de Oliveira Barbosa, M; de Oliveira, SA; Ferreira Pinto, A; Laranjeira Miranda Filho, CA; Lima Leite, AC; Lucena, JP; Rodrigues Oliveira, A, 2022) |
| "Schistosomiasis is one of the most devastating tropical diseases in the world." | 1.72 | Use of wogonin as a cooperative drug with praziquantel to better combat schistosomiasis. ( Cheng, PC; Hung, MY; Pekkle Lam, HY; Peng, SY, 2022) |
| "Schistosoma mansoni infection is endemic in Ethiopia." | 1.72 | Efficacy of Praziquantel Treatment and ( Ali, TE; Atnafie, SA; Berhanu, MS; Chekol, AA; Kebede, HB, 2022) |
| "Praziquantel treatment of infected mice fed with a standard diet (IN-PZQ) resulted in a significant reduction of worm and egg burdens and a normalization of iron and calcium levels." | 1.72 | Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection. ( Abou-Bacar, A; Boukeng Jatsa, H; Brunet, J; Cannet, C; Gipwe Feussom, N; Greigert, V; Kadji Fassi, JB; Kamgang, R; Kamtchouing, P; Kenfack, CM; Membe Femoe, U; Pfaff, AW; Tchuem Tchuenté, LA; Tienga Nkondo, E, 2022) |
| "Plumbagin treatment restored hepatic enzymes activity to nearly normal levels and induced an increase in catalase, SOD, GSH, total thiol and GST in liver tissue homogenate." | 1.72 | Anti-inflammatory, antioxidant, anti-fibrotic and schistosomicidal properties of plumbagin in murine schistosomiasis. ( Abdel-Latif, M; Abuelsaad, ASA; Allam, GA; Bakery, HH; Elkenawy, AE; Khalil, RG, 2022) |
| "Praziquantel (PZQ) treatment presents low efficacy and adverse effects in parasites juvenile stages." | 1.72 | Synthesis, in vitro schistosomicidal activity and ultrastructural alterations caused by thiosemicarbazones and thiazolidinones against juvenile and adult Schistosoma mansoni worms (Sambon, 1907). ( Alves de Lima, MDC; Alves, LC; Bezerra de Mélo, ME; Brayner, FA; de Almeida Júnior, ASA; de Oliveira, JF; do Nascimento, AV; Feitosa, APS; Júnior, NCP; Leite, NMS; Tavares da Rocha, RE, 2022) |
| "Schistosoma mansoni liver fibrosis is a complicated multicellular process involving numerous cytokines, chemokines, and growth factors." | 1.72 | Role of IL-17A in enhancing liver fibrosis induced by TGF-β1 and IL-13 in Schistosoma mansoni infected mice. ( Abd Allah, MH; Abo-Sheishaa, GA; Bayoumy, AS; Shalash, IR; Zaalouk, TK, 2022) |
| "Lactoferrin is an 80 KDa iron-binding glycoprotein that plays a significant role in the innate immune system and is considered to be an important microbicide molecule." | 1.72 | Evaluation of faecal lactoferrin as a morbidity biomarker in Schistosoma mansoni infection. ( Abdo, S; Elhadad, H; Mohamed, MA; Mohamed, MM, 2022) |
| "Although the pathogenesis of liver fibrosis has been intensively studied, the choice of effective treatment is still inadequate." | 1.72 | Antifibrotic and anthelminthic effect of casticin on Schistosoma mansoni-infected BALB/c mice. ( Chang, KC; Cheng, PC; Lam, HYP; Lan, YC; Liang, TR; Peng, SY, 2022) |
| "Praziquantel treatment significantly reduced systemic OPN levels and liver collagen deposition, indicating that OPN could be a reliable tool for monitoring PZQ efficacy and fibrosis regression in murine schistosomiasis." | 1.62 | Praziquantel pharmacotherapy reduces systemic osteopontin levels and liver collagen content in murine schistosomiasis mansoni. ( Pereira, FEL; Pereira, TA; Souza, MM; Trindade Santos, E; Vaz de Melo Trindade, G, 2021) |
| "To assess the status of intestinal schistosomiasis among preschool-aged (PSAC) and school-aged children (SAC) and to compare the efficacy of praziquantel (PZQ) in both groups." | 1.62 | Intestinal schistosomiasis among preschool and school-aged children in a rural setting near Alexandria: initiative for elimination. ( Allam, AF; Dewair, MM; Elsheredy, A; Farag, HF; Hagras, NA; Ibrahim, HS; Salem, A; Shehab, AY, 2021) |
| "Metformin (Met) is a well-known drug for type 2 diabetes." | 1.62 | An adjuvant effect of Metformin as an anti-fibrotic agent when administered with the anti-schistosomal Praziquantel in Schistosoma mansoni infected mice. ( El-Naggar, SA; El-Said, KS; Harras, SF; Salama, WM, 2021) |
| "Praziquantel was the positive control in the experiment." | 1.56 | In vivo effect of essential oil of Mentha x villosa and its active compound against Schistosoma mansoni (Sambon, 1907). ( Alves, LC; Barbosa-Filho, JM; Cavalcanti, MGS; Freitas, CF; Matos-Rocha, TJ; Melo, ES; Santos, AF; Santos, FABD; Suassuna, ASCL; Veras, DL, 2020) |
| "Schistosomiasis has continued to plague low-resource areas of the Nigerian population." | 1.56 | Schistosomiasis Control in Nigeria: Moving Round the Circle? ( Oyeyemi, OT, 2020) |
| "Mean prevalence of urogenital schistosomiasis was 24." | 1.56 | An outbreak of intestinal schistosomiasis, alongside increasing urogenital schistosomiasis prevalence, in primary school children on the shoreline of Lake Malawi, Mangochi District, Malawi. ( Al-Harbi, MH; Baxter, H; Hesketh, J; Juziwelo, L; Kayuni, SA; LaCourse, EJ; Lally, D; Mainga, B; Makaula, P; Musaya, J; O'Ferrall, AM; Stothard, JR, 2020) |
| "Omeprazole is a proton pump inhibitor which is reported to have antiparasitic properties." | 1.51 | Assessment of the potential therapeutic effects of omeprazole in Schistosoma mansoni infected mice. ( Abdel Ghaffar, AE; Alshenawy, HA; Elgendy, DI; Ellakany, AR, 2019) |
| "Only 17% of the children had relevant intestinal schistosomiasis related knowledge and very few of them knew any of the S." | 1.51 | Factors associated with relevant knowledge of intestinal schistosomiasis and intention to participate in treatment campaigns: a cross sectional survey among school children at Ijinga Island on Lake Victoria, North-Western Tanzania. ( Kasang, C; Kreibich, S; Mazigo, HD; Mueller, A; Parisi, S; Puchner, K, 2019) |
| " Unfortunately, it exhibits low oral bioavailability which can compromise its efficacy." | 1.51 | Niosomes for enhanced activity of praziquantel against Schistosoma mansoni: in vivo and in vitro evaluation. ( Abd Elazeem, MA; Aboul Asaad, IA; El Maghraby, GM; El-Kowrany, SI; El-Nouby, KA; Zoghroban, HS, 2019) |
| " Susceptibility of worms in vivo was first assessed during passage 5 when mice infected with PZQ-selected schistosomes were dosed with a lethal dose of 3 × 300 mg/kg PZQ resulting in only a 10% reduction in worm number compared to control treatment." | 1.51 | Transcriptomic analysis of reduced sensitivity to praziquantel in Schistosoma mansoni. ( Bu, L; Cunningham, C; Cupit, PM; Sanchez, MC, 2019) |
| "Praziquantel has proven to be effective against this parasitic disease, though there are increasing concerns regarding tolerance/resistance that calls for new drugs." | 1.51 | In vitro schistosomicidal activity of tamoxifen and its effectiveness in a murine model of schistosomiasis at a single dose. ( Allegretti, SM; Corrêa, SAP; Mendes, T; Miguel, DC; Oliveira, RN; Vieira, KM, 2019) |
| "Schistosomiasis is traditionally classified into an acute and a chronic phase, although a precise temporal distinction between the two phases has not been established." | 1.51 | Restaging Pulmonary Schistosomiasis. ( Angheben, A; Bisoffi, Z; Buonfrate, D; Gobbi, F, 2019) |
| "Praziquantel treatment (40 mg/kg) resulted in 96." | 1.51 | Schistosoma mansoni infection among preschool age children attending Erer Health Center, Ethiopia and the response rate to praziquantel. ( Abay, SM; Esmael, A; Kebede, T; Kemal, M; Tadesse, G, 2019) |
| " This work aimed to improve the therapeutic outcome of the only available antischistosomal drug worldwide, praziquantel (PZQ), by incorporating it into a novel carrier, "solid lipid nanoparticles (SLNs)", to enhance its solubility, bioavailability and efficacy." | 1.51 | A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection. ( Al-Shorbagy, MY; Botros, S; El-Feky, GS; El-Lakkany, NM; Radwan, A; Saleh, S; William, S, 2019) |
| "Schistosomiasis mansoni is considered one of the most common fibrotic diseases resulting from inflammation and deposition of fibrous tissue around parasitic eggs trapped in the liver, causing morbidity and mortality." | 1.48 | Impact of treatment with a Protein Tyrosine Kinase Inhibitor (Genistein) on acute and chronic experimental Schistosoma mansoni infection. ( El-Sayed, SH; Mahmoud, SS; Negm, MSI; Raafat, A; Rizk, EMA; Sobhy, MMK, 2018) |
| "Praziquantel was not available in any of the HF." | 1.48 | Capacity gaps in health facilities for case management of intestinal schistosomiasis and soil-transmitted helminthiasis in Burundi. ( Bizimana, P; Muhimpundu, E; Ngenzebuhoro, C; Nsabiyumva, F; Ortu, G; Polman, K; Van Geertruyden, JP, 2018) |
| "Lipid nanocapsules (LNCs) have shown potential to increase the bioavailability and efficacy of orally administered drugs." | 1.48 | Praziquantel-lipid nanocapsules: an oral nanotherapeutic with potential ( Amara, RO; Eissa, MM; El-Azzouni, MZ; El-Khordagui, LK; El-Moslemany, RM; Ramadan, AA, 2018) |
| "Liver fibrosis is a pathological process complicating schistosomiasis." | 1.46 | Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis. ( Ashour, RH; Elhenawy, AA; Megahed, N; Nabih, N; Shalaby, NM, 2017) |
| "Liver fibrosis is the main pathology of schistosomiasis and its complications are the major cause of death in infected cases." | 1.46 | Artichoke leaf extract protects liver of Schistosoma mansoni infected mice through modulation of hepatic stellate cells recruitment. ( Brakat, RM; Mohamed, ASED; Sharaf El-Deen, SA, 2017) |
| "Praziquantel treatment decreased adult-worm burden, but had a larger negative impact on the mean daily number of miracidia, a proxy for fecundity, across all three parasite isolates." | 1.46 | Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study. ( Faust, CL; Lamberton, PHL; Webster, JP, 2017) |
| " Non-compartmental pharmacokinetic analysis was performed using PKsolver." | 1.46 | Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model. ( Abla, N; Haas, H; Keiser, J; Reimers, N; Spangenberg, T; Vargas, M, 2017) |
| "The simvastatin treated group showed shortening and loss of the tubercles and disappearance of the spines with swelling and twisted shape of the worms." | 1.46 | Simvastatin exerts antifibrotic effect and potentiates the antischistosomal effects of praziquantel in a murine model: Role of IL10. ( Aboulfotouh, N; Aladeeb, NM; Elkaref, A; Elmasry, A, 2017) |
| "Prevalence of intestinal schistosomiasis as measured in schoolchildren by Kato-Katz (Mount Elgon = 5." | 1.46 | Intestinal schistosomiasis in Uganda at high altitude (>1400 m): malacological and epidemiological surveys on Mount Elgon and in Fort Portal crater lakes reveal extra preventive chemotherapy needs. ( Adriko, M; Allison, G; Arinaitwe, M; Davies, J; Howell, A; Kabatereine, NB; LaCourse, EJ; Muheki, E; Stanton, MC; Stothard, JR, 2017) |
| " The aim of the present study was to investigate the potential anti-fibrotic effect of human Wharton's jelly-derived mesenchymal stem cells (WJMSCs) combined with praziquantel (PZQ) in S." | 1.43 | Wharton's jelly-derived mesenchymal stem cells combined with praziquantel as a potential therapy for Schistosoma mansoni-induced liver fibrosis. ( Abdelsalam, RM; Attia, YM; El-Khatib, AS; Elkhafif, N; Elmazar, MM; Hammam, OA; Kenawy, SA; Mansour, MT, 2016) |
| " In the current work, the therapeutic efficacy of different limonin dosing protocols was evaluated in experimentally infected mice harboring Schistosoma mansoni (Egyptian strain) juvenile or adult stages." | 1.43 | Dose-response relationship in Schistosoma mansoni juvenile and adult stages following limonin treatment in experimentally infected mice. ( Abdallah, KF; Abou-Ouf, EA; Aly, NS; El-Kholy, AA; Eraky, MA; Hamdan, DI; Hammam, OA; Kishik, SM; Moharam, AF; Rashed, GA, 2016) |
| "Schistosomiasis is the second most significant parasitic disease in children in several African countries." | 1.43 | Schistosomiasis Sustained Control Program in Ethnic Groups Around Ninefescha (Eastern Senegal). ( Barbier, D; Bessin, F; Dewavrin, P; Diawara, L; Diedhiou, K; Dioukhane, EM; Georges, P; Klotz, F; N'Diaye, M; Ndao, B; Talla, I; Vernet, C, 2016) |
| " muris infection at a single oral dosing of 100 mg/kg, despite being significantly (27." | 1.43 | Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris. ( Becker, L; Giacomin, PR; Loukas, A; Pearson, MS; Pickering, D; Smout, MJ; Sotillo, J; Wangchuk, P, 2016) |
| " We conducted the first PZQ pharmacokinetic (PK) and pharmacodynamic (PD) study in young children comparing dosing." | 1.43 | Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy. ( Atuhaire, A; Bustinduy, AL; Corstjens, PL; de Sousa-Figueiredo, JC; Hope, WW; Kabatereine, NB; Roberts, SA; Scott, JT; Stanton, MC; Stothard, JR; Van Dam, GJ; Ward, S; Waterhouse, D, 2016) |
| "Schistosomiasis is a known risk after exposure to freshwater in tropical parts of the world." | 1.43 | Clinical Report: Schistosomiasis Exposure in U.S. Service Personnel During Whitewater Rafting on the Nile River in Jinja, Uganda. ( Maluil, S; Stevens, RA, 2016) |
| "Despite attempts to control intestinal schistosomiasis through school-based mass drug administration (MDA) with praziquantel using school teachers in Uganda, less than 30% of the school children take the treatment in some areas." | 1.42 | Understanding low uptake of mass treatment for intestinal schistosomiasis among school children: a qualitative study in Jinja district, Uganda. ( Katahoire, A; Muhumuza, S; Nuwaha, F; Olsen, A, 2015) |
| "Praziquantel (PZQ) is a highly efficacious anthelmintic against many flatworms including schistosomes." | 1.42 | Evaluation of a method for induction of praziquantel resistance in Schistosoma mansoni. ( Abu El Einin, HM; El Nashar, AS; Hishmat, MG; Lotfy, WM, 2015) |
| "The overall prevalence and intensity of intestinal schistosomiasis among school children in Hayk Number 1 and Hayk Number 2 Primary Schools was found to be 45% and 161 epg, respectively." | 1.42 | A new focus of schistosomiasis mansoni in Hayk town, northeastern Ethiopia. ( Amsalu, G; Erko, B; Mekonnen, Z, 2015) |
| "Schistomiasis was associated with hepatomegaly (adjusted prevalence ratio [aPR] = 1." | 1.42 | Morbidity associated with schistosomiasis before and after treatment in young children in Rusinga Island, western Kenya. ( Davis, SM; Fox, LM; Harris, R; Kareko, EI; Mulama, F; Mwinzi, PM; Ochola, E; Odiere, MR; Rawago, F; Samuels, AM; Wiegand, RE; Won, KY, 2015) |
| "Praziquantel has been distributed using community resource persons in fixed sites and house-to-house visits; however the uptake is still below target coverage." | 1.42 | Uptake of mass drug administration programme for schistosomiasis control in Koome Islands, Central Uganda. ( Bagonza, J; Elliott, AM; Kiracho, EE; Nuwaha, F; Tuhebwe, D; Yeka, A, 2015) |
| " This study focused on improving the biological characteristics of the already-existing antischistosomal praziquantel (PZQ) by incorporating it into montmorillonite (MMT) clay as a delivery carrier to overcome its known bioavailability drawbacks." | 1.42 | Praziquantel in a clay nanoformulation shows more bioavailability and higher efficacy against murine Schistosoma mansoni infection. ( Botros, SS; El-Feky, GS; El-Lakkany, NM; Mohamed, WS; Nasr, HE; Seif El-Din, SH, 2015) |
| " However, this treatment presents limitations such as low and/or erratic bioavailability that can contribute to cases of tolerance." | 1.42 | Effectiveness of hyperbaric oxygen for experimental treatment of schistosomiasis mansoni using praziquantel-free and encapsulated into liposomes: assay in adult worms and oviposition. ( Allegretti, SM; de Oliveira, CN; de Souza, AL; Dolder, MA; Frezza, TF; Giorgio, S; Gremião, MP; Joazeiro, PP; Prado, CC, 2015) |
| "Neuroschistosomiasis is a severe disease caused by the presence of Schistosoma eggs and/or adult worms in the central nervous system." | 1.42 | Myeloradicular Form of Neuroschistosomiasis in a Six-Year-Old Boy Infected With Schistosoma mansoni. ( Barros, VM; Braga Júnior, LL; Monteiro-Neto, V; Salgado, IA; Salgado, JV; Serra, SC; Silva, MJ, 2015) |
| "Mass treatment with praziquantel applied once to endemic communities led to an important and long-lasting sustained reduction of S." | 1.40 | Long-term effect of mass chemotherapy, transmission and risk factors for Schistosoma mansoni infection in very low endemic communities of Venezuela. ( Ballén, D; Hofstede, SN; Incani, RN; Tami, A; van Liere, GA, 2014) |
| " Adverse events were monitored within 4h after dosing by the survey team and 24h after treatment using a questionnaire." | 1.39 | Efficacy and safety of two closely spaced doses of praziquantel against Schistosoma haematobium and S. mansoni and re-infection patterns in school-aged children in Niger. ( Barkiré, N; Djibo, A; Fenwick, A; Garba, A; Gouvras, AN; Labbo, R; Lamine, MS; Sebangou, H; Sofo, B; Utzinger, J; Webster, JP, 2013) |
| "High intensities in mixed infections may influence disease epidemiology and control warranting further studies." | 1.39 | Praziquantel treatment of school children from single and mixed infection foci of intestinal and urogenital schistosomiasis along the Senegal River Basin: monitoring treatment success and re-infection patterns. ( Diaw, OT; Faye, DS; Rollinson, D; Seye, MM; Sousa-Figueiredo, JC; Stothard, JR; Webster, BL, 2013) |
| " All 8 animals were treated under anaesthesia by oral gavage with PZQ at 60 mg/kg dosing that was well tolerated." | 1.39 | Intestinal schistosomiasis in chimpanzees on Ngamba Island, Uganda: observations on liver fibrosis, schistosome genetic diversity and praziquantel treatment. ( Adriko, M; Ajarova, L; Arinaitwe, M; Betson, M; Kabatereine, NB; Mopya, S; Mugisha, L; Rukundo, J; Standley, CJ; Stothard, JR, 2013) |
| " Children remained under medical supervision for 4h and adverse events were recorded." | 1.39 | Safety and efficacy of praziquantel syrup (Epiquantel®) against Schistosoma haematobium and Schistosoma mansoni in preschool-aged children in Niger. ( Alfari, A; Aouami, MA; Djibo, A; Fenwick, A; Garba, A; Lamine, MS; Phillips, AE; Tahirou, A; Utzinger, J, 2013) |
| "Praziquantel (PZQ) is an isoquinoline derivative (2-cyclohexylcarbonyl-1, 2, 3, 6, 7, 11b-hexahydro-4H-pyrazino{2,1-a}-isoquinoline-4-one), and is currently the drug of choice for all forms of schistosomiasis." | 1.38 | Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis. ( Ain-Shoka, AA; Badawy, AA; Ebeid, FA; El-Lakkany, NM; El-Maadawy, WH; Hammam, OA, 2012) |
| "Its effect on the extent of liver fibrosis, through estimation of hepatic hydroxyproline and hepatic collagen content in liver hydrolysates, was also evaluated." | 1.38 | Tranilast ameliorates impaired hepatic functions in Schistosoma mansoni-infected mice. ( Ammar, EM; Elkashef, WF; Gameil, NM; Said, E; Said, SA, 2012) |
| " Taken together, these findings suggest that long term administration of ASU may result in a mild course of murine schistosomiasis and may be a promising complementary treatment to PZQ." | 1.38 | Evaluation of avocado/soybean unsaponifiable alone or concurrently with praziquantel in murine schistosomiasis. ( Soliman, MF, 2012) |
| " No dosage significantly (p>0." | 1.38 | Susceptibility of a Brazilian wild rodent isolate of Schistosoma mansoni to praziquantel in mice. ( Barros, Lde A; Costa-Silva, M; Garcia, JS; Machado-Silva, JR; Maldonado-Júnior, A; Neves, RH; Rodrigues-Silva, R, 2012) |
| "However, PZQ does not improve liver fibrosis." | 1.38 | Therapeutic effect of alpha lipoic acid combined with praziquantel on liver fibrosis induced by Schistosoma mansoni challenged mice. ( Aabdel-Wahab, S; Abdel-Hafeez, EH; Abdulla, AM; Ahmad, AK; Mosalem, FA, 2012) |
| " This work correlates the physical properties and the dissolution behavior of PZQ-polyvinylpyrrolidone (PVP) solid dispersion (SD) at the ratios of 1:1 and 3:7 with its oral bioavailability and its in vivo efficacy against Schistosoma mansoni (S." | 1.38 | Bioavailability and in vivo efficacy of a praziquantel-polyvinylpyrrolidone solid dispersion in Schistosoma mansoni-infected mice. ( El-Lakkany, N; Heikal, L; Seif El-Din, SH, 2012) |
| "Nevertheless, cerebral vasculitis in later stages of the Schistosoma mansoni infection have not yet been described in living subjects." | 1.38 | Cerebral vasculitis associated with Schistosoma mansoni infection. ( Abou-Bacar, A; Camuset, G; Candolfi, E; Christmann, D; Hansmann, Y; Lefebvre, N; Marescaux, C; Wolff, V, 2012) |
| " Adverse events were assessed and graded 4 and 24 hours posttreatment by interviewing mothers/guardians." | 1.38 | Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium. ( Coulibaly, JT; Keiser, J; Knopp, S; N'gbesso, YK; N'Goran, EK; Utzinger, J, 2012) |
| "Exploratory laparatomy confirmed intussusception of the terminal part of the ileum into the caecum, extending to the ascending colon." | 1.37 | Intestinal schistosomiasis associated with intussusception: a case report. ( Chandika, AB; Heukelbach, J; Mazigo, HD; Rambau, P; Zinga, M, 2011) |
| "This study investigates the efficacy, bioavailability and drug metabolizing enzymes mainly involved in the metabolism of the commercial brands of praziquantel (PZQ) in Egypt in comparison with the original pure powder." | 1.37 | Comparative efficacy and bioavailability of different praziquantel brands. ( Botros, S; El-Lakkany, N; Ibrahim, M; Sabra, AN; Seif el-Din, SH, 2011) |
| "Praziquantel has been used to treat schistosome infections since 1979 and currently is the only chemotherapeutic agent in production for this purpose, raising concerns about the potential for the emergence of drug resistance." | 1.37 | Schistosoma mansoni population structure and persistence after praziquantel treatment in two villages of Bahia, Brazil. ( Barbosa, LM; Blank, WA; Blanton, RE; Carmo, TM; Costa, JM; Reis, EA; Reis, MG; Silva, LK; Test, MR, 2011) |
| "A case is presented of intestinal schistosomiasis due to both Schistosoma intercalatum and Schistosoma mansoni in a 30-year-old man from Senegal with discussion of diagnostic approach, species identification and determination of the effect of treatment." | 1.36 | Intestinal schistosomiasis caused by both Schistosoma intercalatum and Schistosoma mansoni. ( Adamis, G; Astriti, M; Choreftaki, T; Delis, V; Moustakas, G; Papaliodi, E; Sarri, K; Tzanetou, K, 2010) |
| "Praziquantel chemotherapy has been the focus of the Schistosomiasis Control Program in Brazil for the past two decades." | 1.36 | Spatial distribution of Schistosoma mansoni infection before and after chemotherapy with two praziquantel doses in a community of Pernambuco, Brazil. ( Barbosa, CS; Carvalho, OS; Domingues, AL; Favre, TC; Felipe, KT; Galvão, AF; Guimarães, RJ; Pereira, AP; Pieri, OS; Zani, LC, 2010) |
| "To control intestinal schistosomiasis at a national level in sub-Saharan Africa, there is a need for field-applicable markers to measure morbidity associated with this disease." | 1.36 | Intestinal schistosomiasis in mothers and young children in Uganda: investigation of field-applicable markers of bowel morbidity. ( Betson, M; Kabatereine, NB; Rowell, C; Sousa-Figueiredo, JC; Stothard, JR, 2010) |
| "Hepatosplenomegaly was more marked in schistosome and malaria co-infected mice compared to either infection separately." | 1.35 | Plasmodium yoelii: adverse outcome of non-lethal P. yoelii malaria during co-infection with Schistosoma mansoni in BALB/c mouse model. ( Kumar, N; Sangweme, D; Shiff, C, 2009) |
| "Neuroschistosomiasis is a rare but serious complication of the schistosomiasis that can only be made after complete parasite identification and careful differential diagnosis." | 1.35 | [Sciatica after return from Mali: case report of schistosomal myelopathy]. ( Botterel, F; Brugières, P; Hosseini, H; Liance, M; Perignon, A; Poirier, P, 2009) |
| "G1b: treated with Praziquantel (PZQ) in a dose of 500 mg/kg for two consecutive days." | 1.35 | Parasitological and histo-pathological studies on schistosomiasis mansoni infected mice and treated with praziquatel and/or oltipraz. ( Morsy, GH, 2009) |
| "Treatment with praziquantel induced a significant decline in both ECP and EPX, but only a non-significant reduction in faecal MPO." | 1.35 | Assessment of Schistosoma mansoni induced intestinal inflammation by means of eosinophil cationic protein, eosinophil protein X and myeloperoxidase before and after treatment with praziquantel. ( Dunne, DW; Kabatereine, NB; Reimert, CM; Tukahebwa, EM; Vennervald, BJ, 2008) |
| "Portopulmonary hypertension is characterized by a chronic liver disease associated with a mean pulmonary artery pressure >25 mmHg at rest, an increased pulmonary vascular resistance and a capillary pulmonary pressure <15 mmHg with portal hypertension." | 1.34 | [Portopulmonary hypertension due to schistosomiasis in two Malagasy patients]. ( Rajaona, HR; Rajaonarivelo, P; Ramanampamonjy, RM; Razafimahefa, SH, 2007) |
| "Schistosomiasis mansoni is usually a chronic infection that leads to long-term, systemic exposure to schistosome antigens." | 1.34 | T regulatory cell levels decrease in people infected with Schistosoma mansoni on effective treatment. ( Black, CL; Colley, DG; Karanja, DM; Muok, EM; Mwinzi, PN; Secor, WE; Watanabe, K, 2007) |
| " The recommended dosage of PZQ is a single 40 mg/kg oral dose, and each of these patients continued to pass viable Schistosoma mansoni eggs despite three successive doses at or above this level." | 1.33 | Current status of sensitivity to praziquantel in a focus of potential drug resistance in Egypt. ( Amer, N; Bennett, JL; Botros, S; Day, TA; El-Ghannam, M; Sayed, H, 2005) |
| "The therapeutic effect of a subcurative dosage of praziquantel (PZQ) on Schistosoma mansoni infected mice and resistance to challenged worm infection after treatment were assessed and compared with conventional treatment using a curative dosage of PZQ." | 1.33 | Therapeutic effect of subcurative dose praziquantel on Schistosoma mansoni infected mice and resistance to challenge infection after treatment. ( Chaiworaporn, R; Janecharut, T; Kitikoon, V; Maneerat, Y; Matsuda, H; Ramasoota, P; Rojekittikhun, W, 2005) |
| "The level of drug-metabolizing enzymes (cytochrome P450 [CYP450] and cytochrome b5 [cyt b5]) and the bioavailability of praziquantel (PZQ) were investigated in batches of mice infected with Schistosoma mansoni displaying either a decreased susceptibility to PZQ ("EE2" and "BANL"-isolates), or a normal susceptibility to the drug ("CD" isolate)." | 1.33 | Drug-metabolizing enzymes and praziquantel bioavailability in mice harboring Schistosoma mansoni isolates of different drug susceptibilities. ( Botros, SS; Ebeid, FA; El-Din, SH; El-Lakkany, NM; Sabra, AN, 2006) |
| " These effects were more pronounced with dosing regimens launched before the time of oviposition." | 1.32 | Activity of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine against Schistosomiasis mansoni in mice. ( Botros, S; Hammam, O; Holý, A; William, S; Zídek, Z, 2003) |
| "Schistosomiasis mansoni is a tropical helminthic disease characterized by parasite egg-induced granulomatous inflammation and cumulative fibrosis." | 1.32 | Expression of matrix metalloproteinases and their inhibitors during the resorption of schistosome egg-induced fibrosis in praziquantel-treated mice. ( Boros, DL; Gerard, HC; Hudson, AP; Singh, KP, 2004) |
| "Histamine-release was not correlated to plasma concentrations of total or parasite-specific IgE, nor to specific IgG4 plasma concentrations." | 1.32 | Changes in IgE- and antigen-dependent histamine-release in peripheral blood of Schistosoma mansoni-infected Ugandan fishermen after treatment with praziquantel. ( Cahen, P; Dunne, DW; Fitzsimmons, C; Hoffmann, KF; Jones, FM; Joseph, S; Kabatereine, NB; Kariuki, HC; Kazibwe, F; Kimani, G; Mwatha, JK; Ouma, JH; Reimert, C; Satti, MZ; Skov, PS; Vennervald, BJ, 2004) |
| "Liver fibrosis is the main pathological finding in schistosomiasis that occurs after many years of infection." | 1.32 | HTLV-1 modifies the clinical and immunological response to schistosomiasis. ( Alcantara, L; Carvalho, EM; Gonzalez, D; Gonzalez, T; Guerreiro, JB; Ho, JL; Neva, F; Passos, J; Porto, AF; Santos, SB, 2004) |
| "The effect of coinfection on HIV disease progression varied with species." | 1.32 | Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda. ( Brown, M; Elliott, AM; Hughes, P; Kizza, M; Quigley, MA; Rowland, S; Watera, C; Whitworth, JA, 2004) |
| "Management of patients with bleeding oesophageal varices comprises of mainly diagnostic endoscopy, sclerotherapy and band ligation." | 1.32 | Can somatostatin control acute bleeding from oesophageal varices in Schistosoma mansoni patients?[ISRCTN63456799]. ( Chatterjee, S; Van Marck, E, 2004) |
| " When the dosage was increased to 600 mg/kg, after 4 h lesions on the tegument similar to those induced by Pra or L-Pra were seen, but less severe." | 1.31 | Tegumental changes in adult Schistosoma mansoni harboured in mice treated with praziquantel enantiomers. ( Binggui, S; Chollet, J; Shuhua, X; Tanner, M, 2000) |
| "Schistosomiasis is one of the main health problems hindering socio-economic development in Egypt." | 1.31 | Histological assessment of tissue repair after treatment of human schistosomiasis. ( Abdel-Hadi, AM; Talaat, M, 2000) |
| "To determine whether drug treatment of Schistosomiasis mansoni infection leads to a reduction in plasma HIV-1 RNA concentration in coinfected individuals." | 1.31 | The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals. ( Andove, J; Colley, DG; Folks, TM; Karanja, DM; Lawn, SD; Mwinzia, P; Secor, WE, 2000) |
| "Treatment with praziquantel of individuals from the area residing temporarily in an urban region with no transmission, and re-treatment after 3 weeks of non-cured individuals within the area resulted in normal cure rates (78-88%)." | 1.31 | Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence. ( De Vlas, SJ; Diop, M; Engels, D; Faye, D; Gryseels, B; Guissé, F; Ly, A; Mbaye, A; Polman, K; Stelma, FF; Tchuem-Tchuenté, LA; Van Lieshout, L, 2001) |
| "Schistosomiasis mansoni is an endemic fluke infection in South America, the Caribbean, and Africa." | 1.31 | Schistosomal myelopathy: urologic manifestations and urodynamic findings. ( Alaor de Figueiredo, J; Arap, MA; Arap, S; Gabriel, AJ; Gomes, CM; Trigo-Rocha, F, 2002) |
| "Treatment with ibuprofen or naproxen either alone or in combination with praziquantel or praziquantel alone reduced significantly the granuloma diameters." | 1.31 | Effect of combined chemotherapy and anti-inflammatory drugs on murine schistosomiasis. ( Mahmoud, MR; Nosseir, MM; Zoheiry, MM, 2002) |
| "Tests for a haemochromatosis gene and its type showed a homozygotic C282Y variant." | 1.30 | [Flu-like infection and liver disease after a stay in the tropics]. ( Gehrke, S; Nothdurft, HD; Schneider, M; Stremmel, W, 1999) |
| "Surprisingly low cure rates were repeatedly observed after treatment with a standard dosage of praziquantel in a recently established Schistosoma mansoni focus in northern Senegal." | 1.30 | The contribution of host-related factors to low cure rates of praziquantel for the treatment of Schistosoma mansoni in Senegal. ( Deelder, A; Diakhate, M; Falcao Ferreira, ST; Gryseels, B; Guissé, F; Polman, K; Sow, S; Stelma, FF; van Dam, GJ; van Lieshout, L, 1999) |
| "Urinary schistosomiasis was also rapidly spreading." | 1.29 | Epidemic schistosomiasis in the delta of the Senegal River Basin, Senegal: responses of the health care system. ( Kongs, A; Talla, I; Verlé, P, 1994) |
| "The authors report a case of transverse myelitis caused by Schistosoma mansoni." | 1.29 | Schistosoma mansoni infection involving the spinal cord. Case report. ( Onofrio, BM; Parisi, JE; Ueki, K, 1995) |
| "In praziquantel treated group the level of testosterone was lowered 10, 20 & 30 days post treatment, progesterone and 17 beta-estradiol fell 30 days post treatment after primary rise." | 1.29 | Effect of praziquantel on sex hormone levels in murine schistosomiasis mansoni. ( Abdalla, KF; Abdel-Aziz, SM; Afifi, LM; el Fakahany, AF; el-Hamshary, AS, 1994) |
| "Cimetidine was tested in doses of 50, 100 and 200 mg/kg for 2 consecutive days; praziquantel was given in doses of 100 and 500 mg/kg for 2 consecutive days." | 1.29 | Treatment of experimental schistosomiasis mansoni with praziquantel alone and combined with cimetidine. ( Bennet, JL; Botros, SS; Ebeid, FA; Metwally, AA, 1994) |
| "Praziquantel (40 mg/kg) was given at months 0, 12, 24, and 36 to those showing eggs in the feces with a single 28-mg Kato slide." | 1.29 | Impact of repeated community-based selective chemotherapy on morbidity due to schistosomiasis mansoni. ( Engels, D; Gryseels, B; Nkulikyinka, L, 1994) |
| "Oxamniquine-treated worms required 4-8 days for these effects to be apparent." | 1.29 | Temporal differences in praziquantel- and oxamniquine-induced tegumental damage to adult Schistosoma mansoni: implications for drug-antibody synergy. ( Fallon, PG; Fookes, RE; Wharton, GA, 1996) |
| "Praziquantel was found to be more effective, it gave 60% cure rate after the first dose, increased to 100% after the second dose, than oxamniquine which had 37% and 74% cure rates respectively." | 1.28 | Alternate chemotherapy in experimental schistosomiasis. ( Farghaly, AM; Hassan, MM; Ismail, MM; Mohamed, FE; Youssef, SM, 1992) |
| "Treatment with Praziquantel resulted in substantial restoration of the production of 14CO2 from [14C]tryptophan." | 1.28 | Tryptophan metabolism and vitamin B6 nutritional status in patients with schistosomiasis mansoni and in infected mice. ( Bender, DA; Njagi, EN; Okelo, GB, 1992) |
| "Praziquantel was more effective in the destruction of spined papillae, wrinkling and disturbing the interpapillar spaces." | 1.28 | Scanning electron microscopy of the tegumental surface of in vivo treated Schistosoma mansoni (Saudi Arabian geographical strain) with oxamniquine and praziquantel. ( Banaja, AA; Ghandour, AM; Shalaby, IM, 1991) |
| "In praziquantel-treated mice, the reduction in the per cent resistance was accompanied by a diminution in the size of hepatic granulomata and its in vivo correlate the delayed foot pad swelling." | 1.28 | Effect of specific chemotherapy on the immune response and resistance to reinfection in experimental Schistosomiasis mansoni. ( Azab, ME; Botros, SS; el-Garem, AA; el-Nahal, HM; Hassan, SI; Shaker, ZA, 1990) |
| " Control mice and mice infected with Schistosoma mansoni were dosed with PZQ and their urines were examined for the presence of metabolites using a triple-quadrupole mass spectrometer (tandem mass spectrometer)." | 1.28 | Metabolism studies of the antischistosomal drug praziquantel using tandem mass spectrometry: qualitative identification of 17 hydroxylated metabolites from mouse urine. ( Abramson, FP; Ali, MH; Cohn, VH; Fetterolf, DD, 1990) |
| " The reduction in adult worm recovery after dosing with 50 mg/kg oxamniquine was 89." | 1.28 | Effects of praziquantel and oxamniquine on a Saudi Arabian strain of Schistosoma mansoni in mice. ( Banaja, AA; Ghandour, AM; Shalaby, IM, 1990) |
| "Upon treatment with praziquantel (100 mg/kg body wt), this level was significantly less within 1 week." | 1.28 | Schistosoma mansoni: detection of circulating antigens in murine schistosomiasis by antigen-capture sandwich ELISA using a monoclonal antibody. ( Barsoum, IS; Colley, DG; Kamal, KA, 1990) |
| "Chronic schistosomiasis mansoni is associated with impaired cell-mediated immune responsiveness (CMI)." | 1.28 | Altered generation of interleukin 1 in chronic human schistosomiasis mansoni. ( Correia Dacal, AR; Richter, J; Taupitz, S; Vergetti Siqueira, JG; Zwingenberger, K, 1990) |
| " A recombinant hepatitis B vaccine was safe and immunogenic when given to patients with schistosomiasis mansoni." | 1.28 | Safety and immunogenicity of a recombinant hepatitis B vaccine in patients infected with Schistosoma mansoni. ( Bassily, S; el-Ghorab, N; el-Masry, NA; Hyams, KC, 1990) |
| "The high frequence of hepatomegaly, and to a lesser extent of splenomegaly, which were shown to be related to schistosome infection, however, have disappeared." | 1.28 | Eight years of targeted mass treatment of Schistosoma mansoni infection in Maniema, Zaire. ( de Caluwe, P; Polderman, AM, 1989) |
| "Praziquantel (PZQ) is a racemic compound composed of equal proportions of its optical isomers, levo- and dextro-PZQ." | 1.28 | A comparison of the antischistosomal effect of levo- and dextro-praziquantel on Schistosoma japonicum and S. mansoni in mice. ( Irie, Y; Nara, T; Ohmae, H; Tanaka, M; Utsunomiya, H; Yasuraoka, K, 1989) |
| "In praziquantel-treated mice (500 mg/kg for 2 days orally), the reduction in the percent resistance (45." | 1.28 | Levamisole restored the compromised state of immunity after specific chemotherapy in experimental schistosomiasis mansoni. ( Azab, ME; Botros, SS; el-Garem, A; el-Nahal, HM; Hassan, SI; Shaker, ZA, 1989) |
| "Praziquantel is a broad spectrum anti-helminthic drug active against a variety of parasitic trematodes and cestodes." | 1.27 | Effects of anti-schistosomal chemotherapy on immune responses, protection and immunity. III. An effective regimen of praziquantel does not alter immune capabilities of normal mice. ( Colley, DG; Tawfik, AF, 1986) |
| "Oxamniquine was equally effective in children receiving it in both 1981 and 1983, and the efficacy of praziquantel resembled that of oxamniquine." | 1.27 | Immunity after treatment of human schistosomiasis mansoni. III. Long-term effects of treatment and retreatment. ( arap Siongok, TK; Bensted-Smith, R; Butterworth, AE; Dalton, PR; Kariuki, HC; Koech, D; Mugambi, M; Ouma, JH; Sturrock, RF, 1987) |
| "Praziquantel treatment of S." | 1.27 | Effect of praziquantel on Schistosoma mansoni eggs: leucine aminopeptidase (LAP) activity and anti-LAP antibodies. ( Dresden, MH; Matsuda, H; Xu, YZ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 92 (11.02) | 18.7374 |
| 1990's | 186 (22.28) | 18.2507 |
| 2000's | 162 (19.40) | 29.6817 |
| 2010's | 269 (32.22) | 24.3611 |
| 2020's | 126 (15.09) | 2.80 |
| Authors | Studies |
|---|---|
| Boissier, J | 2 |
| Coslédan, F | 2 |
| Robert, A | 2 |
| Meunier, B | 2 |
| Ingram, K | 1 |
| Yaremenko, IA | 1 |
| Krylov, IB | 1 |
| Hofer, L | 1 |
| Terent'ev, AO | 1 |
| Keiser, J | 20 |
| Sharma, LK | 1 |
| Cupit, PM | 4 |
| Goronga, T | 1 |
| Webb, TR | 2 |
| Cunningham, C | 4 |
| Heimburg, T | 1 |
| Chakrabarti, A | 1 |
| Lancelot, J | 2 |
| Marek, M | 1 |
| Melesina, J | 1 |
| Hauser, AT | 1 |
| Shaik, TB | 1 |
| Duclaud, S | 1 |
| Robaa, D | 2 |
| Erdmann, F | 1 |
| Schmidt, M | 1 |
| Romier, C | 1 |
| Pierce, RJ | 3 |
| Jung, M | 1 |
| Sippl, W | 2 |
| Wu, J | 1 |
| Wang, C | 1 |
| Häberli, C | 1 |
| White, KL | 1 |
| Shackleford, DM | 1 |
| Chen, G | 1 |
| Dong, Y | 1 |
| Charman, SA | 1 |
| Vennerstrom, JL | 2 |
| Gardner, JMF | 1 |
| Mansour, NR | 1 |
| Bell, AS | 1 |
| Helmby, H | 1 |
| Bickle, Q | 2 |
| Padalino, G | 3 |
| El-Sakkary, N | 1 |
| Liu, LJ | 1 |
| Liu, C | 1 |
| Harte, DSG | 1 |
| Barnes, RE | 1 |
| Sayers, E | 1 |
| Forde-Thomas, J | 1 |
| Whiteland, H | 1 |
| Bassetto, M | 1 |
| Ferla, S | 2 |
| Johnson, G | 1 |
| Jones, AT | 1 |
| Caffrey, CR | 2 |
| Chalmers, I | 1 |
| Brancale, A | 2 |
| Hoffmann, KF | 9 |
| Webb, EL | 8 |
| Edielu, A | 1 |
| Wu, HW | 1 |
| Kabatereine, NB | 30 |
| Tukahebwa, EM | 15 |
| Mubangizi, A | 1 |
| Adriko, M | 6 |
| Elliott, AM | 16 |
| Hope, WW | 2 |
| Mawa, PA | 7 |
| Friedman, JF | 2 |
| Bustinduy, AL | 4 |
| Mnkugwe, RH | 2 |
| Ngaimisi Kitabi, E | 1 |
| Kinung'hi, S | 9 |
| Kamuhabwa, AAR | 1 |
| Minzi, OM | 1 |
| Aklillu, E | 2 |
| Al-Haidari, SA | 1 |
| Mahdy, MAK | 1 |
| Al-Mekhlafi, AM | 1 |
| Al Murisi, WMS | 1 |
| Thabit, AAQ | 1 |
| Al-Amad, MA | 1 |
| Al-Shamahi, H | 1 |
| Bahashwan, OS | 1 |
| Al Serouri, A | 1 |
| Moses, A | 2 |
| Kibwika, B | 1 |
| Faust, CL | 3 |
| Lamberton, PHL | 6 |
| Chulkov, EG | 2 |
| Smith, E | 1 |
| Rohr, CM | 3 |
| Yahya, NA | 2 |
| Park, SK | 2 |
| Scampavia, L | 1 |
| Spicer, TP | 1 |
| Marchant, JS | 4 |
| Straily, A | 1 |
| Kavere, EA | 1 |
| Wanja, D | 1 |
| Wiegand, RE | 10 |
| Montgomery, SP | 11 |
| Mwaki, A | 1 |
| Eleveld, A | 1 |
| Secor, WE | 22 |
| Odiere, MR | 5 |
| Amer, EI | 2 |
| El-Azzouni, MZ | 5 |
| El-Bannan, RT | 1 |
| Shalaby, TI | 1 |
| El-Achy, SN | 1 |
| Gomaa, MM | 1 |
| Gasan, TA | 1 |
| Kuipers, ME | 1 |
| Roberts, GH | 1 |
| Forde-Thomas, JE | 1 |
| Wilson, S | 9 |
| Wawrzyniak, J | 1 |
| Chalmers, IW | 5 |
| Mughal, MN | 1 |
| Grevelding, CG | 2 |
| Haeberlein, S | 1 |
| Morais, CS | 1 |
| Mengarda, AC | 3 |
| Miguel, FB | 2 |
| Enes, KB | 1 |
| Rodrigues, VC | 1 |
| Espírito-Santo, MCC | 1 |
| Siyadatpanah, A | 1 |
| Wilairatana, P | 1 |
| Couri, MRC | 2 |
| de Moraes, J | 4 |
| Lam, HYP | 2 |
| Cheng, PC | 3 |
| Peng, SY | 3 |
| Le Clec'h, W | 1 |
| Chevalier, FD | 1 |
| Mattos, ACA | 1 |
| Strickland, A | 1 |
| Diaz, R | 1 |
| McDew-White, M | 1 |
| Allan, F | 3 |
| Webster, BL | 5 |
| Webster, JP | 23 |
| Emery, AM | 1 |
| Rollinson, D | 6 |
| Djirmay, AG | 1 |
| Al Mashikhi, KM | 1 |
| Al Yafae, S | 1 |
| Idris, MA | 1 |
| Moné, H | 1 |
| Mouahid, G | 1 |
| LoVerde, P | 1 |
| Anderson, TJC | 1 |
| Bais, S | 2 |
| Norwillo, A | 1 |
| Ruthel, G | 2 |
| Herbert, DR | 2 |
| Freedman, BD | 2 |
| Greenberg, RM | 4 |
| Atwa, MTM | 1 |
| Abd-Elrazek, AM | 1 |
| Salem, NIS | 1 |
| Kura, K | 1 |
| Ayabina, D | 1 |
| Hollingsworth, TD | 2 |
| Anderson, RM | 1 |
| El Saftawy, EA | 1 |
| El-Dardiry, MA | 2 |
| Abd-Elaal, AA | 1 |
| Negm, MSI | 2 |
| Amin, NM | 1 |
| Cotton, JA | 4 |
| Doyle, SR | 2 |
| Mielke, N | 1 |
| Johnson, S | 1 |
| Bahl, A | 1 |
| Fadladdin, YAJ | 1 |
| Xue, M | 1 |
| Zhang, X | 2 |
| Chen, J | 1 |
| Liu, F | 1 |
| Xu, J | 1 |
| Xie, J | 1 |
| Yang, Y | 2 |
| Yu, W | 2 |
| Qiu, H | 1 |
| Xue, J | 1 |
| Jiang, J | 1 |
| Liu, Y | 2 |
| Shallom, SJ | 1 |
| Zelazny, AM | 1 |
| Giri, AR | 1 |
| Kaur, N | 1 |
| Yarrarapu, SNS | 1 |
| Rottman Pietrzak, KA | 1 |
| Santos, C | 2 |
| Lowman, PE | 1 |
| Niaz, S | 1 |
| Franco, PM | 1 |
| Sanghavi, DK | 1 |
| Zhu, D | 1 |
| Liang, R | 1 |
| Li, Z | 2 |
| Cheng, L | 1 |
| Ren, J | 1 |
| Guo, Y | 1 |
| Wang, M | 1 |
| Chai, H | 1 |
| Niu, Q | 1 |
| Yang, S | 1 |
| Bai, J | 1 |
| Yu, H | 1 |
| Zhang, H | 1 |
| Qin, X | 1 |
| Sahrakorpi, N | 1 |
| Engberg, E | 1 |
| Stach-Lempinen, B | 1 |
| Tammelin, TH | 1 |
| Kulmala, J | 1 |
| Roine, RP | 1 |
| Koivusalo, SB | 1 |
| Cheng, W | 1 |
| Pang, H | 1 |
| Campen, MJ | 1 |
| Zhang, J | 2 |
| Li, Y | 1 |
| Gao, J | 2 |
| Ren, D | 1 |
| Ji, X | 1 |
| Rothman, N | 1 |
| Lan, Q | 1 |
| Zheng, Y | 1 |
| Leng, S | 1 |
| Hu, Z | 1 |
| Tang, J | 1 |
| Dong, Q | 1 |
| Song, N | 1 |
| Qin, N | 1 |
| Chen, C | 1 |
| Sun, X | 1 |
| Easton, J | 1 |
| Mulder, H | 1 |
| Plyler, E | 1 |
| Neale, G | 1 |
| Walker, E | 1 |
| Li, Q | 1 |
| Ma, X | 1 |
| Chen, X | 1 |
| Huang, IC | 1 |
| Yasui, Y | 1 |
| Ness, KK | 1 |
| Hudson, MM | 1 |
| Robison, LL | 1 |
| Wang, Z | 1 |
| Subota, A | 1 |
| Spotswood, N | 1 |
| Roach, M | 1 |
| Goodarzi, Z | 1 |
| Holroyd-Leduc, J | 1 |
| Park, EA | 1 |
| Graves, SA | 1 |
| Menda, Y | 1 |
| Membe Femoe, U | 2 |
| Boukeng Jatsa, H | 2 |
| Greigert, V | 2 |
| Brunet, J | 2 |
| Cannet, C | 2 |
| Kenfack, MC | 2 |
| Gipwe Feussom, N | 2 |
| Kadji Fassi, JB | 3 |
| Tienga Nkondo, E | 2 |
| Abou-Bacar, A | 3 |
| Pfaff, AW | 2 |
| Dimo, T | 1 |
| Kamtchouing, P | 3 |
| Tchuem Tchuenté, LA | 5 |
| Fahmy, AM | 1 |
| William, S | 11 |
| Hegab, A | 1 |
| Tm, D | 1 |
| Rahman, MM | 1 |
| McFadden, G | 1 |
| Laranjeira Miranda Filho, CA | 1 |
| de Oliveira Barbosa, M | 1 |
| Rodrigues Oliveira, A | 1 |
| Ferreira Pinto, A | 1 |
| Araújo, DL | 1 |
| Lucena, JP | 1 |
| de Araújo, RE | 1 |
| de Oliveira, SA | 1 |
| Lima Leite, AC | 1 |
| Pekkle Lam, HY | 1 |
| Hung, MY | 1 |
| Sabra, AA | 1 |
| Salem, MB | 1 |
| Hammam, OA | 7 |
| El-Lakkany, NM | 8 |
| Paulino, ÉT | 1 |
| Ribeiro de Lima, M | 1 |
| Viçosa, AL | 1 |
| da Silva, CH | 1 |
| Salomon, CJ | 1 |
| Real, DA | 1 |
| Leonardi, D | 1 |
| Mello Silva, CC | 1 |
| de Moraes Neto, AHA | 1 |
| Dos Reis, LFC | 1 |
| Cerdeira, CD | 1 |
| Gagliano, GS | 1 |
| de Figueiredo, ABT | 1 |
| Ferreira, JH | 1 |
| Castro, AP | 1 |
| Souza, RLM | 2 |
| Marques, MJ | 2 |
| Berhanu, MS | 1 |
| Atnafie, SA | 1 |
| Ali, TE | 1 |
| Chekol, AA | 1 |
| Kebede, HB | 1 |
| Kenfack, CM | 1 |
| Kamgang, R | 1 |
| Probst, A | 1 |
| Biendl, S | 1 |
| Vianney, TJ | 1 |
| Berger, DJ | 2 |
| Sankaranarayanan, G | 1 |
| Serubanja, J | 1 |
| Nakawungu, PK | 1 |
| Besigye, F | 1 |
| Sanya, RE | 3 |
| Holroyd, N | 2 |
| Berriman, M | 3 |
| Bakery, HH | 1 |
| Allam, GA | 1 |
| Abuelsaad, ASA | 1 |
| Abdel-Latif, M | 1 |
| Elkenawy, AE | 1 |
| Khalil, RG | 1 |
| Tavares da Rocha, RE | 1 |
| de Almeida Júnior, ASA | 1 |
| Júnior, NCP | 1 |
| do Nascimento, AV | 1 |
| Leite, NMS | 1 |
| de Oliveira, JF | 1 |
| Alves de Lima, MDC | 1 |
| Feitosa, APS | 1 |
| Bezerra de Mélo, ME | 1 |
| Brayner, FA | 2 |
| Alves, LC | 3 |
| Saad El-Din, MI | 1 |
| Gad El-Hak, HN | 1 |
| Ghobashy, MA | 1 |
| Elrayess, RA | 1 |
| Araújo Fiuza, J | 1 |
| Colt, S | 1 |
| Gambogi de Ornellas, L | 1 |
| Ferreira Matoso, L | 1 |
| Gazzinelli, A | 3 |
| Corrêa-Oliveira, R | 5 |
| Abd Allah, MH | 1 |
| Zaalouk, TK | 1 |
| Abo-Sheishaa, GA | 1 |
| Shalash, IR | 1 |
| Bayoumy, AS | 1 |
| Mewamba, EM | 1 |
| Tiofack, AAZ | 1 |
| Kamdem, CN | 1 |
| Tchounkeu, EY | 1 |
| Tatang, RJA | 1 |
| Mengoue, LET | 1 |
| Mbagnia, MCT | 1 |
| Njiokou, F | 1 |
| Casacuberta-Partal, M | 4 |
| Womeni, HM | 1 |
| Simo, G | 1 |
| Elhadad, H | 1 |
| Mohamed, MA | 1 |
| Mohamed, MM | 1 |
| Abdo, S | 1 |
| Nogueira, RA | 1 |
| Lira, MGS | 1 |
| Licá, ICL | 1 |
| Frazão, GCCG | 1 |
| Dos Santos, VAF | 1 |
| Filho, ACCM | 1 |
| Rodrigues, JGM | 1 |
| Miranda, GS | 1 |
| Carvalho, RC | 1 |
| Nascimento, FRF | 1 |
| Aboagye, IF | 3 |
| Addison, YAA | 3 |
| Wang, N | 3 |
| Peng, HQ | 3 |
| Gao, CZ | 3 |
| Cheng, YH | 3 |
| Sun, MT | 3 |
| Qu, GL | 3 |
| Lu, DB | 3 |
| Pham, K | 3 |
| Mtalitinya, GS | 3 |
| Aristide, C | 4 |
| Airewele, EA | 3 |
| Nyakaru, DK | 3 |
| McMahon, P | 3 |
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| Corstjens, PLAM | 10 |
| J de Dood, C | 3 |
| van Dam, GJ | 15 |
| Changalucha, JM | 3 |
| Mazigo, HD | 9 |
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| Hoekstra, PT | 2 |
| van Lieshout, L | 8 |
| Tsonaka, R | 2 |
| Assaré, RK | 7 |
| Silué, KD | 5 |
| N'Goran, EK | 18 |
| N'Gbesso, YK | 4 |
| Brienen, EAT | 1 |
| Roestenberg, M | 5 |
| Knopp, S | 7 |
| Utzinger, J | 28 |
| Coulibaly, JT | 14 |
| Hassan, EM | 1 |
| Osman, GY | 2 |
| Mohamed, AH | 5 |
| Salem, TA | 2 |
| Palygin, O | 1 |
| Mujumbusi, L | 1 |
| Nalwadda, E | 1 |
| Ssali, A | 1 |
| Pickering, L | 1 |
| Seeley, J | 2 |
| Meginnis, K | 1 |
| Elhenawy, AA | 3 |
| Elmehankar, MS | 1 |
| Nabih, N | 3 |
| Elzoheiry, MA | 1 |
| Hany, H | 1 |
| El-Gamal, R | 1 |
| Aboukamar, WA | 1 |
| Sousa, MS | 3 |
| Meneses, GC | 1 |
| Dam, GJV | 1 |
| Galvão, RLF | 1 |
| Pinheiro, MCC | 2 |
| Martins, AMC | 1 |
| Daher, EF | 2 |
| Bezerra, FSM | 2 |
| Assandé Aka, R | 1 |
| Ouattara, M | 6 |
| Aka, NAD | 1 |
| Ogutu, B | 1 |
| Rawago, F | 3 |
| Bagchus, WM | 1 |
| Bödding, M | 1 |
| Kourany-Lefoll, E | 1 |
| Tappert, A | 1 |
| Yin, X | 1 |
| Bezuidenhout, D | 1 |
| Badenhorst, H | 1 |
| Huber, E | 1 |
| Dälken, B | 1 |
| Haj-Ali Saflo, O | 1 |
| Maganga, JK | 1 |
| Campbell, CH | 6 |
| Angelo, T | 1 |
| Mosha, J | 1 |
| Mwanga, JR | 1 |
| Kinung'hi, SM | 2 |
| Hamdan, ZK | 1 |
| Soliman, MI | 1 |
| Taha, HA | 1 |
| Khalil, MMH | 1 |
| Nigm, AH | 1 |
| Alghamdi, T | 1 |
| Salem, DA | 1 |
| El-Refaei, MF | 1 |
| Alwan, SN | 1 |
| Taylor, AB | 1 |
| Rhodes, J | 1 |
| Tidwell, M | 1 |
| McHardy, SF | 1 |
| LoVerde, PT | 2 |
| Takeuchi, T | 1 |
| Nakamura, R | 2 |
| Hamasaki, M | 1 |
| Oyama, M | 1 |
| Hamano, S | 4 |
| Hatanaka, T | 1 |
| Anwar, FS | 1 |
| Abdel-Malek, AR | 1 |
| Salem, SH | 1 |
| Farouk, M | 1 |
| Ali, MF | 1 |
| Abdelrady, YA | 1 |
| Sayed, AM | 1 |
| Koopman, JPR | 2 |
| Houlder, EL | 1 |
| Janse, JJ | 3 |
| Lamers, OAC | 1 |
| Sijtsma, JC | 1 |
| de Dood, C | 1 |
| Hilt, ST | 1 |
| Ozir-Fazalalikhan, A | 2 |
| Kuiper, VP | 1 |
| Roozen, GVT | 1 |
| de Bes-Roeleveld, LM | 1 |
| Kruize, YCM | 1 |
| Wammes, LJ | 1 |
| Smits, HH | 1 |
| van Amerongen-Westra, IM | 1 |
| Meij, P | 2 |
| Jochems, SP | 2 |
| van Diepen, A | 3 |
| Yazdanbakhsh, M | 4 |
| Hokke, CH | 5 |
| Obonyo, CO | 1 |
| Were, VO | 1 |
| Wamae, P | 1 |
| Muok, EMO | 1 |
| Shen, Y | 4 |
| Olsen, A | 10 |
| King, CH | 8 |
| Kittur, N | 7 |
| Binder, S | 7 |
| Zhang, F | 1 |
| Whalen, CC | 3 |
| Mwinzi, PNM | 7 |
| Magnussen, P | 7 |
| Colley, DG | 24 |
| Chami, GF | 1 |
| Alharbi, RA | 1 |
| Alwajeeh, TS | 1 |
| Assabri, AM | 1 |
| Almalki, SSR | 1 |
| Alruwetei, A | 1 |
| Azazy, AA | 1 |
| Mueller, A | 4 |
| Fuss, A | 3 |
| Ziegler, U | 1 |
| Kaatano, GM | 3 |
| Nalwoga, A | 1 |
| Chihota, B | 1 |
| Miley, W | 1 |
| Walusimbi, B | 1 |
| Nassuuna, J | 1 |
| Nkurunungi, G | 1 |
| Labo, N | 1 |
| Cose, S | 5 |
| Whitby, D | 1 |
| Newton, R | 1 |
| Sung, MH | 1 |
| Ellakany, AR | 1 |
| Elgendy, DI | 1 |
| Alshenawy, HA | 1 |
| Abdel Ghaffar, AE | 1 |
| Tawfeek, GM | 1 |
| Baki, MHA | 1 |
| Ibrahim, AN | 1 |
| Mostafa, MAH | 1 |
| Fathy, MM | 1 |
| Diab, MSEDM | 1 |
| Matos-Rocha, TJ | 1 |
| Cavalcanti, MGS | 1 |
| Veras, DL | 1 |
| Santos, AF | 1 |
| Freitas, CF | 1 |
| Suassuna, ASCL | 1 |
| Melo, ES | 1 |
| Barbosa-Filho, JM | 1 |
| Santos, FABD | 1 |
| Mishra, P | 1 |
| Colombe, S | 1 |
| Paul, N | 1 |
| Mlingi, J | 1 |
| Tosiri, I | 1 |
| Kashangaki, P | 1 |
| Nagai, H | 1 |
| Kalluvya, SE | 1 |
| de Dood, CJ | 3 |
| Corstjens, PL | 2 |
| Mngara, J | 1 |
| Silva, LK | 3 |
| Barbosa, LM | 3 |
| Kovach, JD | 1 |
| Dos Santos Teixeira, R | 1 |
| Soares, ÊS | 1 |
| Cardoso, CW | 1 |
| Marques, RVM | 1 |
| Dos Santos, TP | 1 |
| G Reis, M | 1 |
| Blanton, RE | 4 |
| Karanja, DMS | 6 |
| Carneiro, NFF | 2 |
| Caldeira, AP | 1 |
| Katz, N | 12 |
| Oliveira, ÁA | 3 |
| Siqueira, LMV | 2 |
| Oliveira, E | 4 |
| Silveira, MF | 1 |
| Enk, MJ | 4 |
| Coelho, PMZ | 3 |
| Crotti, M | 1 |
| Oguttu, D | 1 |
| Wamboko, A | 1 |
| Adekanle, EK | 1 |
| Kabatereine, N | 1 |
| Norton, AJ | 4 |
| Gower, CM | 3 |
| Parisi, S | 1 |
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| Langenberg, MCC | 2 |
| Hoogerwerf, MA | 1 |
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| Feijt, C | 1 |
| van Schuijlenburg, R | 1 |
| Manurung, MD | 1 |
| Sartono, E | 1 |
| van der Beek, MT | 1 |
| Winkel, BMF | 1 |
| Verbeek-Menken, PH | 1 |
| Stam, KA | 1 |
| van Leeuwen, FWB | 1 |
| Visser, LG | 1 |
| Meité, A | 4 |
| Amoah, AS | 1 |
| Aly, I | 1 |
| Ibrahim, EH | 1 |
| Hamad, RS | 1 |
| Sayed, HEL | 1 |
| Attiyah, SMN | 1 |
| E-Komy, W | 1 |
| Ghramh, HA | 1 |
| Alshehri, A | 1 |
| Alsyaad, KM | 1 |
| Alshehri, M | 1 |
| Kilany, M | 1 |
| Morsy, K | 1 |
| El-Kott, AF | 1 |
| Taha, R | 1 |
| Armoo, S | 1 |
| Cunningham, LJ | 1 |
| Campbell, SJ | 1 |
| Aboagye, FT | 1 |
| Boampong, FK | 1 |
| Hamidu, BA | 1 |
| Osei-Atweneboana, MY | 1 |
| Stothard, JR | 18 |
| Adams, ER | 1 |
| Hasby Saad, MA | 1 |
| El-Anwar, N | 1 |
| Jacobson, JA | 1 |
| Fleming, FM | 4 |
| Matendechero, SH | 1 |
| Castleman, JD | 1 |
| Kabole, FM | 1 |
| Ramzy, RMR | 2 |
| Musuva, R | 2 |
| Andrade, GN | 1 |
| Ezeamama, AE | 1 |
| Fenwick, A | 20 |
| Phillips, AE | 2 |
| Gazzinelli-Guimaraes, PH | 1 |
| Dhanani, N | 1 |
| Ferro, J | 1 |
| Hamidou, AA | 1 |
| Garba, A | 7 |
| Yoon, N | 1 |
| Wang, X | 1 |
| Lo, NC | 1 |
| Alsallaq, R | 1 |
| Ndeffo-Mbah, M | 1 |
| Li, E | 1 |
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| Spencer, L | 1 |
| Salem, AE | 1 |
| Rashwan, EA | 1 |
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| Delgado, VS | 2 |
| Suárez, DP | 1 |
| el-Hawey, AM | 6 |
| Abou-Taleb, SA | 1 |
| el-Gammal, HA | 1 |
| Abdel-Rahman, MM | 1 |
| Sabry, AA | 1 |
| Youssef, SM | 1 |
| Mohamed, FE | 1 |
| el Malatawy, A | 1 |
| el Habashy, A | 1 |
| Lechine, N | 1 |
| Dixon, H | 1 |
| Davis, A | 1 |
| Mott, KE | 1 |
| Abdel-Rahim, IM | 2 |
| Kaiser, C | 2 |
| Franke, D | 2 |
| Schlake, J | 2 |
| Elsheikh, M | 2 |
| Junghanss, T | 1 |
| Weiss, N | 1 |
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| Hamed, RR | 1 |
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| el Garem, AA | 1 |
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| Tanaka, TM | 1 |
| Khayyal, MT | 3 |
| Piper, KP | 2 |
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| Hockley, DJ | 1 |
| McLaren, DJ | 7 |
| Barsoum, IS | 3 |
| Kamal, KA | 2 |
| Shalaby, IM | 2 |
| Bommert, K | 1 |
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| de Souza, CP | 1 |
| Coura Filho, P | 1 |
| Bruce, JI | 3 |
| Kinoti, GK | 1 |
| Zwingenberger, K | 7 |
| Hohmann, A | 1 |
| de Brito, MC | 1 |
| Ritter, M | 1 |
| Massoud, AM | 4 |
| el-Rakieby, A | 2 |
| Royzeik, MS | 1 |
| Nassar, MO | 2 |
| Homeida, MA | 2 |
| el Tom, I | 2 |
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| Wilkins, PP | 1 |
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| Slemenda, SB | 1 |
| Tsang, VC | 1 |
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| Feldmeier, H | 8 |
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| Irschick, E | 2 |
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| Shaw, MK | 2 |
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| Fetterolf, DD | 2 |
| Abramson, FP | 2 |
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| Sher, A | 4 |
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| Hilberath, GW | 1 |
| Harms, G | 3 |
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| el-Masry, NA | 3 |
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| Stuiver, PC | 1 |
| Smith, SJ | 2 |
| Abou Basha, LM | 1 |
| Fikry, N | 1 |
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| Norden, AP | 1 |
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| Farid, Z | 5 |
| Woody, J | 2 |
| Kamal, M | 2 |
| Wahib, AA | 1 |
| Ossman, OM | 1 |
| el Zahaby, AA | 1 |
| Ripert, C | 1 |
| Appriou, M | 1 |
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| Ambassa, P | 1 |
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| de Caluwe, P | 2 |
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| Nara, T | 2 |
| Irie, Y | 2 |
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| Salafsky, B | 1 |
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| Li, LH | 1 |
| Mueller, J | 1 |
| Ellenberger, B | 1 |
| Elsaghier, AA | 1 |
| Siqueira Vergetti, JG | 1 |
| Janssen-Rosseck, R | 1 |
| Huber, C | 1 |
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| Jansen-Rosseck, R | 1 |
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| Harries, AD | 2 |
| Fryatt, R | 1 |
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| Kardaman, MW | 2 |
| Greenfield, DI | 1 |
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| Barth, WF | 1 |
| Tawfik, AF | 3 |
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| Sabah, AA | 4 |
| Fletcher, C | 3 |
| Webbe, G | 3 |
| Hassan, I | 1 |
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| el-Ridi, AM | 4 |
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| Ata, AA | 2 |
| el-Raziky, EH | 4 |
| el-Khashab, M | 2 |
| el-Badrawy, N | 2 |
| Schlisio, W | 1 |
| Ziegler, K | 1 |
| Abdel Baki, MH | 1 |
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| Coulanges, P | 2 |
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| Pique, G | 1 |
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| Brejt, H | 1 |
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| Shalaby, MA | 1 |
| Grunstein, P | 1 |
| Broquie, G | 1 |
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| Daffalla, AA | 3 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II PK/PD Driven Dose Finding Trial of Praziquantel in Children Under Four[NCT03640377] | Phase 2 | 600 participants (Anticipated) | Interventional | 2021-02-01 | Recruiting | ||
| Establishing a Single-sex Controlled Human Schistosomiasis Infection Model: Safety and Dose Finding[NCT02755324] | 17 participants (Actual) | Interventional | 2016-10-27 | Completed | |||
| Repeated Doses of Praziquantel in Schistosomiasis Treatment (RePST): An Open Label, Randomized Controlled Trial of Single vs. Multiple Treatments of Praziquantel in Intestinal African Schistosomiasis in Côte d'Ivoire[NCT02868385] | Phase 3 | 167 participants (Actual) | Interventional | 2018-10-01 | Completed | ||
| The Effect of One Versus Two Praziquantel Treatments on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria in Uganda[NCT00215267] | 540 participants (Anticipated) | Interventional | 2005-09-30 | Completed | |||
| Effects of Arachidonic Acid Supplementation on Schistosomiasis Mansoni Infection in Egyptian School Children[NCT02144389] | 335 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
| Schistosoma Haematobium Infections Among Schoolchildren in Central Sudan One Year After Treatment With Praziquantel[NCT01558336] | Phase 3 | 520 participants (Actual) | Interventional | 2008-08-31 | Completed | ||
| Changes in HIV Viral Load in Patients Undergoing Treatment for Filarial Infection[NCT00344279] | 1,000 participants (Anticipated) | Observational | 2005-08-08 | Completed | |||
| Can Anthelminthic Treatment Delay the Progression of HIV? Randomised Open-label Trial Testing Presumptive Anthelminthic Treatment on Progression of HIV in ART-naïve HIV-positive Patients in a Rural African Setting With Presumed High Prevalence of Helminth[NCT00817713] | 295 participants (Actual) | Interventional | 2009-01-31 | Terminated (stopped due to Terminated prematurely due to recruitment difficulties. Expansion to more study sites not planned.) | |||
| Study on the Role of Antioxidant Micronutrients on the Reversal of Schistosomal Peri-portal Fibrosis of the Liver.[NCT01260012] | 414 participants (Anticipated) | Interventional | 2010-01-31 | Recruiting | |||
| Randomized, Double Blind, Placebo Controlled Trial of Albendazole in Soil-Transmitted Helminth and HIV-1 co-Infected Kenyan Individuals to Determine the Effect of Such Treatment on HIV-1 Disease Progression and Genital Shedding.[NCT00130910] | 234 participants (Actual) | Interventional | 2006-03-31 | Completed | |||
| Empiric Therapy of Helminth Co-infection to Reduce HIV-1 Disease Progression[NCT00507221] | 948 participants (Actual) | Interventional | 2008-02-29 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
42 reviews available for praziquantel and Schistosoma mansoni Infection
| Article | Year |
|---|---|
Topics: Adult; Aging; Aluminum; Alzheimer Disease; Animals; Anti-Bacterial Agents; Artemisia annua; Body Mas | 2022 |
Improving translational power in antischistosomal drug discovery.
Topics: Animals; Drug Discovery; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis; Schistosomiasis m | 2022 |
Praziquantel: An update on the mechanism of its action against schistosomiasis and new therapeutic perspectives.
Topics: Adult; Animals; Anthelmintics; Humans; Praziquantel; Schistosoma; Schistosoma mansoni; Schistosomias | 2022 |
Praziquantel efficacy, urinary and intestinal schistosomiasis reinfection - a systematic review.
Topics: Anthelmintics; Child; Humans; Praziquantel; Reinfection; Schistosomiasis haematobia; Schistosomiasis | 2023 |
Praziquantel efficacy, urinary and intestinal schistosomiasis reinfection - a systematic review.
Topics: Anthelmintics; Child; Humans; Praziquantel; Reinfection; Schistosomiasis haematobia; Schistosomiasis | 2023 |
Praziquantel efficacy, urinary and intestinal schistosomiasis reinfection - a systematic review.
Topics: Anthelmintics; Child; Humans; Praziquantel; Reinfection; Schistosomiasis haematobia; Schistosomiasis | 2023 |
Praziquantel efficacy, urinary and intestinal schistosomiasis reinfection - a systematic review.
Topics: Anthelmintics; Child; Humans; Praziquantel; Reinfection; Schistosomiasis haematobia; Schistosomiasis | 2023 |
Praziquantel efficacy, urinary and intestinal schistosomiasis reinfection - a systematic review.
Topics: Anthelmintics; Child; Humans; Praziquantel; Reinfection; Schistosomiasis haematobia; Schistosomiasis | 2023 |
Praziquantel efficacy, urinary and intestinal schistosomiasis reinfection - a systematic review.
Topics: Anthelmintics; Child; Humans; Praziquantel; Reinfection; Schistosomiasis haematobia; Schistosomiasis | 2023 |
Praziquantel efficacy, urinary and intestinal schistosomiasis reinfection - a systematic review.
Topics: Anthelmintics; Child; Humans; Praziquantel; Reinfection; Schistosomiasis haematobia; Schistosomiasis | 2023 |
Praziquantel efficacy, urinary and intestinal schistosomiasis reinfection - a systematic review.
Topics: Anthelmintics; Child; Humans; Praziquantel; Reinfection; Schistosomiasis haematobia; Schistosomiasis | 2023 |
Praziquantel efficacy, urinary and intestinal schistosomiasis reinfection - a systematic review.
Topics: Anthelmintics; Child; Humans; Praziquantel; Reinfection; Schistosomiasis haematobia; Schistosomiasis | 2023 |
Praziquantel versus praziquantel associated with immunomodulators in mice infected with schistosoma mansoni: A systematic review and meta-analysis.
Topics: Adjuvants, Immunologic; Animals; Anthelmintics; Immunologic Factors; Mice; Models, Animal; Praziquan | 2020 |
Schistosomiasis Consortium for Operational Research and Evaluation (SCORE): Its Foundations, Development, and Evolution.
Topics: Animals; Disease Reservoirs; Disease Vectors; History, 21st Century; Humans; Mass Drug Administratio | 2020 |
Contributions of the Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) to Schistosomiasis Control and Elimination: Key Findings and Messages for Future Goals, Thresholds, and Operational Research.
Topics: Africa; Animals; Anthelmintics; Antigens, Helminth; Biomarkers; Child; Feces; Glycoproteins; Health | 2020 |
SCORE Studies on the Impact of Drug Treatment on Morbidity due to
Topics: Adolescent; Animals; Child; Cohort Studies; Female; Humans; Kenya; Male; Mass Drug Administration; M | 2020 |
Application of Schistosomiasis Consortium for Operational Research and Evaluation Study Findings to Refine Predictive Modeling of
Topics: Africa South of the Sahara; Animals; Anthelmintics; Child; Cost-Benefit Analysis; Disease Reservoirs | 2020 |
Efficacy and safety of single-dose 40 mg/kg oral praziquantel in the treatment of schistosomiasis in preschool-age versus school-age children: An individual participant data meta-analysis.
Topics: Administration, Oral; Adolescent; Animals; Anthelmintics; Chemoprevention; Child; Child, Preschool; | 2020 |
Activation of transient receptor potential channel Sm.(Schistosoma mansoni)TRPM
Topics: Animals; Anthelmintics; Cestoda; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Tremato | 2020 |
Surgical management outcome of cerebral schistosomiasis: a case report and review of the literature.
Topics: Adult; Brain Diseases; Humans; Male; Praziquantel; Schistosomiasis; Schistosomiasis mansoni; Sudan; | 2021 |
Population level changes in schistosome-specific antibody levels following chemotherapy.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Humans; Immunity, Humoral; Praziquantel; Schistosoma h | 2019 |
Drugs for treating Schistosoma mansoni infection.
Topics: Adolescent; Adult; Child; Commiphora; Humans; Oxamniquine; Plant Extracts; Praziquantel; Randomized | 2013 |
Clinical efficacy and tolerability of praziquantel for intestinal and urinary schistosomiasis-a meta-analysis of comparative and non-comparative clinical trials.
Topics: Africa; Animals; Anthelmintics; Feces; Humans; Incidence; Intestines; Praziquantel; Schistosoma haem | 2014 |
[Schistosomiasis].
Topics: Animals; Biomphalaria; Cross-Sectional Studies; Diagnosis, Differential; Emigrants and Immigrants; F | 2015 |
Epidemiology, of bilharzias (schistosomiasis) in Uganda from 1902 until 2005.
Topics: Animals; Anthelmintics; Biomphalaria; Feces; Humans; Population Surveillance; Praziquantel; Prevalen | 2008 |
Neuroschistosomiasis.
Topics: Adrenal Cortex Hormones; Animals; Cauda Equina; Humans; Hydrocephalus; Intracranial Hypertension; My | 2010 |
Closing the praziquantel treatment gap: new steps in epidemiological monitoring and control of schistosomiasis in African infants and preschool-aged children.
Topics: Africa; Age Factors; Anemia; Animals; Anthelmintics; Child, Preschool; Coinfection; Feces; Female; H | 2011 |
Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition.
Topics: Animals; Anthelmintics; Drug Resistance; Genetic Variation; Genotype; Humans; Praziquantel; Schistos | 2013 |
The impact of schistosomiasis on human nutrition.
Topics: Adolescent; Adult; Child; Child Development; Female; Humans; Male; Nutrition Disorders; Praziquantel | 1993 |
[Hepatosplenic schistosomiasis: case report and clinical review].
Topics: Adult; Animals; Feces; Female; Hepatitis C; Humans; Infant, Newborn; Liver Diseases, Parasitic; Live | 1993 |
[Schistosoma haematobium].
Topics: Animals; Antiplatyhelmintic Agents; Diagnosis, Differential; Humans; Liver Diseases, Parasitic; Praz | 1995 |
[Acute schistosomiasis or Katayama syndrome: apropos of 2 mini-epidemics].
Topics: Adult; Antiplatyhelmintic Agents; Burkina Faso; Contact Tracing; Disease Outbreaks; Female; Humans; | 1996 |
Spinal cord schistosomiasis. A report of 2 cases and review emphasizing clinical aspects.
Topics: Adolescent; Anti-Inflammatory Agents; Antigens, Helminth; Enzyme-Linked Immunosorbent Assay; Humans; | 1999 |
[Schistosomiasis of the spinal cord. The MR aspects in a case].
Topics: Adult; Anthelmintics; Brazil; Drug Therapy, Combination; Female; Humans; Italy; Magnetic Resonance I | 1999 |
Interventions for treating schistosomiasis mansoni.
Topics: Humans; Oxamniquine; Praziquantel; Schistosomiasis mansoni; Schistosomicides | 2000 |
Evolution of schistosomiasis-induced pathology after therapy and interruption of exposure to schistosomes: a review of ultrasonographic studies.
Topics: Adolescent; Adult; Aged; Animals; Anthelmintics; Child; Female; Follow-Up Studies; Gallbladder; Huma | 2000 |
Spinal-cord involvement in the hepato-splenic form of Schistosoma mansoni infection.
Topics: Adolescent; Animals; Anthelmintics; Anti-Inflammatory Agents; Antigens, Helminth; Drug Therapy, Comb | 2001 |
[Schistosoma mansoni schistosomiasis].
Topics: Cause of Death; Chronic Disease; Genetic Predisposition to Disease; Humans; Immunity, Innate; Liver | 2001 |
Interpreting low praziquantel cure rates of Schistosoma mansoni infections in Senegal.
Topics: Animals; Anthelmintics; Drug Resistance; Humans; Praziquantel; Schistosoma mansoni; Schistosomiasis | 2002 |
Spinal cord schistosomiasis in children: analysis of seven cases.
Topics: Adolescent; Anthelmintics; Anti-Inflammatory Agents; Child; Child, Preschool; Female; Humans; Magnet | 2002 |
Immune-dependent chemotherapy of schistosomiasis.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Antigens, Surface; Immunocompromised Host; Male; | 1992 |
Vaccine strategies against schistosomiasis.
Topics: Animals; Antibodies, Helminth; Antibody-Dependent Cell Cytotoxicity; Antigens, Helminth; Disease Mod | 1992 |
[Specific treatment as a weapon for controlling schistosomiasis].
Topics: Adolescent; Brazil; Child; Child, Preschool; Clinical Trials as Topic; Female; Follow-Up Studies; He | 1992 |
New approaches for the control and eradication of schistosomiasis in Venezuela.
Topics: Algorithms; Alkaline Phosphatase; Animals; Antibodies, Helminth; Biomphalaria; Child; Disease Vector | 1992 |
[Control of schistosomiasis mansoni in an area of low transmission].
Topics: Adolescent; Adult; Animals; Biomphalaria; Brazil; Case-Control Studies; Child; Child, Preschool; Dis | 1992 |
Immunological involvement in the efficacy of praziquantel.
Topics: Animals; Immune Tolerance; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni | 1990 |
Experimental animal models in vaccination against schistosomiasis.
Topics: Animals; Guinea Pigs; Immunity, Active; Immunity, Innate; Liver; Lung; Mice; Models, Biological; Pra | 1989 |
The immune-dependence of chemotherapy in experimental schistosomiasis.
Topics: Animals; Antibodies, Helminth; Immune Sera; Immune Tolerance; Immunization, Passive; Mice; Praziquan | 1989 |
Schistosomiasis (Bilharzia) of the spinal cord: case reports and clinical profile.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Male; Praziquantel; Schistosomiasis haem | 1986 |
Spinal cord schistosomiasis: a case report and review of the literature.
Topics: Adult; Humans; Male; Myelitis; Myelitis, Transverse; Paraplegia; Praziquantel; Schistosomiasis manso | 1987 |
86 trials available for praziquantel and Schistosoma mansoni Infection
| Article | Year |
|---|---|
The praziquantel in preschoolers (PIP) trial: study protocol for a phase II PK/PD-driven randomised controlled trial of praziquantel in children under 4 years of age.
Topics: Animals; Anthelmintics; Child; Child, Preschool; Clinical Trials, Phase II as Topic; Humans; Praziqu | 2021 |
Limited efficacy of repeated praziquantel treatment in Schistosoma mansoni infections as revealed by highly accurate diagnostics, PCR and UCP-LF CAA (RePST trial).
Topics: Animals; Anthelmintics; Antigens, Helminth; Feces; Polymerase Chain Reaction; Praziquantel; Prevalen | 2022 |
Efficacy, safety, and palatability of arpraziquantel (L-praziquantel) orodispersible tablets in children aged 3 months to 6 years infected with Schistosoma in Côte d'Ivoire and Kenya: an open-label, partly randomised, phase 3 trial.
Topics: Animals; Anthelmintics; Child, Preschool; Cote d'Ivoire; Female; Humans; Kenya; Male; Praziquantel; | 2023 |
SCHISTOACT: a protocol for an open-label, five-arm, non-inferiority, individually randomized controlled trial of the efficacy and safety of praziquantel plus artemisinin-based combinations in the treatment of Schistosoma mansoni infection.
Topics: Adult; Animals; Anthelmintics; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Equivalen | 2023 |
Five-Year Impact of Different Multi-Year Mass Drug Administration Strategies on Childhood
Topics: Anthelmintics; Child; Cohort Studies; Drug Administration Schedule; Feces; Female; Geography; Humans | 2019 |
Modeling Approaches to Predicting Persistent Hotspots in SCORE Studies for Gaining Control of Schistosomiasis Mansoni in Kenya and Tanzania.
Topics: Animals; Anthelmintics; Child; Feasibility Studies; Feces; Female; Humans; Kenya; Male; Mass Drug Ad | 2020 |
Comparison of School-Based and Community-Wide Mass Drug Administration for Schistosomiasis Control in an Area of Western Kenya with High Initial
Topics: Adolescent; Animals; Anthelmintics; Child; Cluster Analysis; Feces; Female; Humans; Kenya; Male; Mas | 2020 |
A controlled human Schistosoma mansoni infection model to advance novel drugs, vaccines and diagnostics.
Topics: Adolescent; Adult; Animals; Antigens, Helminth; Antiparasitic Agents; Cytokines; Female; Humans; Imm | 2020 |
Efficacy of single versus four repeated doses of praziquantel against Schistosoma mansoni infection in school-aged children from Côte d'Ivoire based on Kato-Katz and POC-CCA: An open-label, randomised controlled trial (RePST).
Topics: Adolescent; Animals; Anthelmintics; Antigens, Helminth; Chemoprevention; Child; Child, Preschool; Co | 2020 |
Impact of Different Mass Drug Administration Strategies for Gaining and Sustaining Control of
Topics: Africa; Animals; Anthelmintics; Child; Drug Administration Schedule; Female; Humans; Male; Mass Drug | 2020 |
Efficacy and safety of praziquantel and dihydroartemisinin piperaquine combination for treatment and control of intestinal schistosomiasis: A randomized, non-inferiority clinical trial.
Topics: Adolescent; Animals; Anthelmintics; Artemisinins; Child; Drug Therapy, Combination; Feces; Female; H | 2020 |
Effectiveness of school-based preventive chemotherapy strategies for sustaining the control of schistosomiasis in Côte d'Ivoire: Results of a 5-year cluster randomized trial.
Topics: Animals; Chemoprevention; Child; Child, Preschool; Cote d'Ivoire; Cross-Sectional Studies; Feces; Fe | 2021 |
Efficacy and safety of praziquantel in preschool-aged and school-aged children infected with Schistosoma mansoni: a randomised controlled, parallel-group, dose-ranging, phase 2 trial.
Topics: Adolescent; Animals; Anthelmintics; Child; Child, Preschool; Cote d'Ivoire; Dose-Response Relationsh | 2017 |
A Persistent Hotspot of Schistosoma mansoni Infection in a Five-Year Randomized Trial of Praziquantel Preventative Chemotherapy Strategies.
Topics: Adult; Animals; Child; Child, Preschool; Cross-Sectional Studies; Geographic Mapping; Humans; Kenya; | 2017 |
Cluster randomized trial comparing school-based mass drug administration schedules in areas of western Kenya with moderate initial prevalence of Schistosoma mansoni infections.
Topics: Animals; Child; Drug Administration Schedule; Feces; Female; Humans; Kenya; Male; Praziquantel; Prev | 2017 |
Rapid clearance of Schistosoma mansoni circulating cathodic antigen after treatment shown by urine strip tests in a Ugandan fishing community - Relevance for monitoring treatment efficacy and re-infection.
Topics: Adolescent; Adult; Aged; Animals; Anthelmintics; Antigens, Helminth; Child; Cohort Studies; Cross-Se | 2017 |
Investigations on the interplays between Schistosoma mansoni, praziquantel and the gut microbiome.
Topics: Adolescent; Animals; Anthelmintics; Biodiversity; Child; Child, Preschool; Cote d'Ivoire; DNA Barcod | 2018 |
Integrating use of point-of-care circulating cathodic antigen rapid diagnostic tests by community health workers during mass drug administration campaigns to improve uptake of praziquantel treatment among the adult population at Kome Island, North-Western
Topics: Adult; Animals; Antigens, Helminth; Community Health Workers; Diagnostic Techniques and Procedures; | 2018 |
Comparison of the Impact of Different Mass Drug Administration Strategies on Infection with
Topics: Animals; Anthelmintics; Child; Drug Administration Schedule; Feces; Female; Humans; Male; Mass Drug | 2018 |
Effect of Schistosoma mansoni infection and its treatment on antibody responses to measles catch-up immunisation in pre-school children: A randomised trial.
Topics: Anthelmintics; Antibodies, Viral; Child, Preschool; Female; Humans; Immunoglobulin G; Male; Measles; | 2019 |
Schistosoma mansoni treatment reduces HIV entry into cervical CD4+ T cells and induces IFN-I pathways.
Topics: Adult; Animals; CD4-Positive T-Lymphocytes; Cells, Cultured; Cervix Uteri; Disease Susceptibility; F | 2019 |
Comparative efficacy of one versus two doses of praziquantel on cure rate of Schistosoma mansoni infection and re-infection in Mayuge District, Uganda.
Topics: Adolescent; Adult; Aged; Animals; Anthelmintics; Child; Drug Administration Schedule; Feces; Female; | 2013 |
Efficacy and side effects of praziquantel in the treatment for Schistosoma mansoni infection in school children in Senbete Town, northeastern Ethiopia.
Topics: Adolescent; Animals; Anthelmintics; Child; Ethiopia; Feces; Female; Humans; Male; Parasite Egg Count | 2013 |
Effect of maternal Schistosoma mansoni infection and praziquantel treatment during pregnancy on Schistosoma mansoni infection and immune responsiveness among offspring at age five years.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Child, Preschool; Female; Humans; Infant; Infant, Newb | 2013 |
Efficacy and safety of arachidonic acid for treatment of Schistosoma mansoni-infected children in Menoufiya, Egypt.
Topics: Adolescent; Animals; Arachidonic Acid; Child; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Rela | 2014 |
Sustaining control of schistosomiasis mansoni in moderate endemicity areas in western Côte d'Ivoire: a SCORE study protocol.
Topics: Anthelmintics; Child; Cote d'Ivoire; Endemic Diseases; Female; Humans; Male; Praziquantel; Prevalenc | 2014 |
Efficacy and safety of arachidonic acid for treatment of school-age children in Schistosoma mansoni high-endemicity regions.
Topics: Adolescent; Animals; Arachidonic Acid; Child; Drug Therapy, Combination; Egypt; Feces; Female; Human | 2015 |
The Lake Victoria Island Intervention Study on Worms and Allergy-related diseases (LaVIISWA): study protocol for a randomised controlled trial.
Topics: Albendazole; Animals; Anthelmintics; Biomarkers; Clinical Protocols; Dermatitis, Atopic; Drug Admini | 2015 |
School-based and community-based actions for scaling-up diagnosis and treatment of schistosomiasis toward its elimination in an endemic area of Brazil.
Topics: Adolescent; Animals; Anthelmintics; Brazil; Child; Community Health Services; Community Participatio | 2015 |
Single Versus Double Dose Praziquantel Comparison on Efficacy and Schistosoma mansoni Re-Infection in Preschool-Age Children in Uganda: A Randomized Controlled Trial.
Topics: Age Factors; Animals; Anthelmintics; Child, Preschool; Female; Humans; Infant; Male; Neglected Disea | 2015 |
Reduced uptake of mass treatment for schistosomiasis control in absence of food: beyond a randomized trial.
Topics: Abdominal Pain; Adolescent; Child; Cross-Sectional Studies; Demography; Diarrhea; Dizziness; Eating; | 2015 |
Sustaining Control of Schistosomiasis Mansoni in Western Côte d'Ivoire: Results from a SCORE Study, One Year after Initial Praziquantel Administration.
Topics: Adolescent; Animals; Anthelmintics; Child; Child, Preschool; Cote d'Ivoire; Cross-Sectional Studies; | 2016 |
Prophylactic effect of artemether on human schistosomiasis mansoni among Egyptian children: A randomized controlled trial.
Topics: Animals; Artemether; Artemisinins; Child; Child, Preschool; Double-Blind Method; Egypt; Female; Huma | 2016 |
Impact of two rounds of praziquantel mass drug administration on Schistosoma mansoni infection prevalence and intensity: a comparison between community wide treatment and school based treatment in western Kenya.
Topics: Adolescent; Adult; Anthelmintics; Child; Child, Preschool; Delivery of Health Care; Feces; Humans; K | 2016 |
Efficacy and Safety of Moxidectin, Synriam, Synriam-Praziquantel versus Praziquantel against Schistosoma haematobium and S. mansoni Infections: A Randomized, Exploratory Phase 2 Trial.
Topics: Adolescent; Animals; Anthelmintics; Antimalarials; Child; Coinfection; Cote d'Ivoire; Drug Therapy, | 2016 |
Effect of chemotherapy with praziquantel on the production of cytokines and morbidity associated with schistosomiasis mansoni.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anthelmintics; Brazil; Cytokines; Female; Human | 2008 |
Effect of praziquantel treatment during pregnancy on cytokine responses to schistosome antigens: results of a randomized, placebo-controlled trial.
Topics: Adolescent; Adult; Antigens, Helminth; Cytokines; Female; Gene Expression Profiling; Humans; Praziqu | 2008 |
Artesunate plus sulfadoxine/pyrimethamine versus praziquantel in the treatment of Schistosoma mansoni in eastern Sudan.
Topics: Adolescent; Animals; Anthelmintics; Antimalarials; Artemisinins; Artesunate; Child; Drug Combination | 2009 |
Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection and antibody responses to schistosome antigens: results of a randomised, placebo-controlled trial.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Double-Blind Method; Female; Human | 2009 |
Comparative randomised trial of high and conventional doses of praziquantel in the treatment of schistosomiasis mansoni.
Topics: Administration, Oral; Adult; Chronic Disease; Dose-Response Relationship, Drug; Feces; Female; Human | 2010 |
Genetic consequences of mass human chemotherapy for Schistosoma mansoni: population structure pre- and post-praziquantel treatment in Tanzania.
Topics: Animals; Child; Cluster Analysis; Genetic Variation; Humans; Phylogeny; Praziquantel; Schistosoma ma | 2010 |
In vitro praziquantel test capable of detecting reduced in vivo efficacy in Schistosoma mansoni human infections.
Topics: Animals; Child; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Male; Praziquante | 2010 |
The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda.
Topics: Animals; Anthelmintics; Ascariasis; Ascaris lumbricoides; Child, Preschool; Drug Therapy, Combinatio | 2011 |
A multicentre randomized controlled trial of the efficacy and safety of single-dose praziquantel at 40 mg/kg vs. 60 mg/kg for treating intestinal schistosomiasis in the Philippines, Mauritania, Tanzania and Brazil.
Topics: Abdominal Pain; Adolescent; Anthelmintics; Brazil; Child; Female; Humans; Incidence; Male; Mauritani | 2011 |
Treatment with anthelminthics during pregnancy: what gains and what risks for the mother and child?
Topics: Albendazole; Ancylostomatoidea; Anemia; Animals; Anthelmintics; Benzimidazoles; Birth Weight; Child; | 2011 |
Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial.
Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Antiprotozoal Agents; Cytokines; Female; Humans | 2011 |
Efficacy of praziquantel syrup versus crushed praziquantel tablets in the treatment of intestinal schistosomiasis in Ugandan preschool children, with observation on compliance and safety.
Topics: Anthelmintics; Child, Preschool; Feces; Female; Follow-Up Studies; Humans; Male; Neglected Diseases; | 2012 |
Performance and safety of praziquantel for treatment of intestinal schistosomiasis in infants and preschool children.
Topics: Animals; Anthelmintics; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Fe | 2012 |
Effects on haemoglobin of multi-micronutrient supplementation and multi-helminth chemotherapy: a randomized, controlled trial in Kenyan school children.
Topics: Adolescent; Albendazole; Anemia; Animals; Anthelmintics; Ascariasis; Ascaris lumbricoides; Child; Di | 2003 |
Efficacy of oxamniquine and praziquantel in the treatment of Schistosoma mansoni infection: a controlled trial.
Topics: Adult; Animals; Brazil; Feces; Female; Humans; Male; Oxamniquine; Parasite Egg Count; Placebos; Praz | 2003 |
Chemotherapy-induced, age-related changes in antischistosome antibody responses.
Topics: Adolescent; Age Factors; Animals; Antibodies, Helminth; Antiplatyhelmintic Agents; Child; Endemic Di | 2003 |
Efficacy of mirazid in comparison with praziquantel in Egyptian Schistosoma mansoni-infected school children and households.
Topics: Adolescent; Adult; Aged; Animals; Child; Egypt; Family Characteristics; Feces; Female; Humans; Male; | 2005 |
Efficacy of myrrh in the treatment of human Schistosomiasis mansoni.
Topics: Adolescent; Adult; Animals; Anthelmintics; Female; Humans; Male; Parasite Egg Count; Praziquantel; S | 2005 |
Impact of drug dosage and brand on bioavailability and efficacy of praziquantel.
Topics: Adolescent; Adult; Animals; Biological Availability; Child; Dose-Response Relationship, Drug; Drug A | 1995 |
Clinical and pharmacokinetic study of praziquantel in Egyptian schistosomiasis patients with and without liver cell failure.
Topics: Absorption; Adolescent; Adult; Bilirubin; Female; Hepatomegaly; Humans; Linear Models; Liver; Liver | 1994 |
Epidemiology, immunology and chemotherapy of Schistosoma mansoni infections in a recently exposed community in Senegal.
Topics: Adolescent; Adult; Age Factors; Aged; Animals; Antibodies, Helminth; Antibody Formation; Child; Chil | 1994 |
Monitoring the efficacy of different doses of praziquantel by quantification of circulating antigens in serum and urine of schistosomiasis patients.
Topics: Administration, Oral; Adolescent; Adult; Animals; Antigens, Helminth; Child; Dose-Response Relations | 1994 |
A community-based randomized trial of praziquantel to control schistosomiasis morbidity in schoolchildren in Zambia.
Topics: Adolescent; Adult; Child; Double-Blind Method; Humans; Praziquantel; Schistosomiasis mansoni; Zambia | 1993 |
Clinical investigation of a population recently infected with Schistosoma mansoni (Richard-Toll, Senegal).
Topics: Adolescent; Adult; Antiplatyhelmintic Agents; Child; Child, Preschool; Disease Outbreaks; Follow-Up | 1996 |
Integrated control trial of schistosomiasis at Nakiwogo fishing village near Entebbe, Uganda.
Topics: Adolescent; Adult; Antiplatyhelmintic Agents; Child; Child, Preschool; Community Participation; Fema | 1996 |
Praziquantel side effects during treatment of Schistosoma mansoni infected pupils in Kibwezi, Kenya.
Topics: Adolescent; Child; Feces; Female; Gastrointestinal Diseases; Headache; Humans; Kenya; Male; Parasite | 1996 |
Effect of early treatment with praziquantel on serum connective tissue metabolite markers in children and adolescents with intestinal schistosomiasis mansoni.
Topics: Adolescent; Animals; Anthelmintics; Antigens, Helminth; Biomarkers; Child; Connective Tissue; Humans | 1997 |
Humoral immune responses in patients with acute Schistosoma mansoni infection who were followed up for two years after treatment.
Topics: Abdomen; Adolescent; Adult; Age Factors; Animals; Antibodies, Helminth; Antiplatyhelmintic Agents; C | 1997 |
Praziquantel in the treatment of Schistosoma mansoni infection: comparison of 40 and 60 mg/kg bodyweight regimens.
Topics: Adolescent; Adult; Age Factors; Antiplatyhelmintic Agents; Child; Child, Preschool; Egypt; Feces; Fe | 1997 |
Therapeutic evaluation of two different dose regimens of praziquantel in a recent Schistosoma mansoni focus in Northern Senegal.
Topics: Adolescent; Antigens, Helminth; Antiplatyhelmintic Agents; Child; Child, Preschool; Female; Humans; | 1997 |
Oxamniquine cures Schistosoma mansoni infection in a focus in which cure rates with praziquantel are unusually low.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Male; Middle Aged; Oxamniquine; Pr | 1997 |
The prevalence and intensity of Schistosoma mansoni infection among residents in two Egyptian villages, at two and twelve months post-treatment with 40 and 60 mg praziquantel per kg body weight at these two villages respectively.
Topics: Adolescent; Adult; Child; Child, Preschool; Egypt; Female; Follow-Up Studies; Humans; Male; Middle A | 1998 |
What is the effect of combining artesunate and praziquantel in the treatment of Schistosoma mansoni infections?
Topics: Adolescent; Adult; Animals; Artemisinins; Artesunate; Child; Child, Preschool; Drug Synergism; Drug | 2000 |
Efficacy of praziquantel against Schistosoma mansoni with particular consideration for intensity of infection.
Topics: Adolescent; Animals; Child; Feces; Female; Humans; Male; Parasite Egg Count; Praziquantel; Schistoso | 2000 |
Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity twenty-three months after treatment with praziquantel.
Topics: Adolescent; Child; Feces; Fibrosis; Follow-Up Studies; Humans; Liver; Morbidity; Parasite Egg Count; | 1992 |
Comparison of different chemotherapy strategies against Schistosoma mansoni in Machakos District, Kenya: effects on human infection and morbidity.
Topics: Adolescent; Age Factors; Child; Cohort Studies; Feces; Follow-Up Studies; Hepatomegaly; Humans; Keny | 1991 |
Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity seven months after treatment with praziquantel.
Topics: Child; Hepatomegaly; Humans; Liver; Liver Cirrhosis; Parasite Egg Count; Praziquantel; Random Alloca | 1991 |
Study of some aspects of cell mediated immune response in bilharzial children on a field level.
Topics: Adolescent; Child; Drug Therapy, Combination; Humans; Immunity, Cellular; Phagocytosis; Praziquantel | 1991 |
Mixed Schistosoma haematobium and S. mansoni infection: effect of different treatments on the serum level of circulating anodic antigen (CAA).
Topics: Animals; Antigens, Helminth; Child; Enzyme-Linked Immunosorbent Assay; Feces; Humans; Male; Oxamniqu | 1990 |
Side effects of praziquantel in bilharzial children on a field level.
Topics: Adolescent; Child; Humans; Praziquantel; Schistosomiasis haematobia; Schistosomiasis mansoni | 1990 |
Studies on liver profile after prolonged praziquantel courses for schistosomiasis mansoni in Egyptian children on a field level.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Child; Humans; Liver; Praziquantel; Schistosomias | 1990 |
Re-infection in human schistosomiasis mansoni: a prospective field study 18 months after praziquantel therapy.
Topics: Adolescent; Adult; Antigens, CD; Biopterins; Child; Child, Preschool; Democratic Republic of the Con | 1990 |
The effect of praziquantel against Schistosoma mansoni-infections in Botswana.
Topics: Animals; Botswana; Child; Child, Preschool; Clinical Trials as Topic; Humans; Parasite Egg Count; Pr | 1989 |
The effect of metrifonate in mixed Schistosoma haematobium and Schistosoma mansoni infections in humans.
Topics: Adolescent; Child; Clinical Trials as Topic; Feces; Humans; Lung; Male; Oxamniquine; Parasite Egg Co | 1986 |
Dosage trial of a combination of oxamniquine and praziquantel in the treatment of schistosomiasis in Zimbabwean schoolchildren.
Topics: Adolescent; Child; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; Huma | 1986 |
Efficacy of low doses of praziquantel for Schistosoma mansoni and S. haematobium.
Topics: Adolescent; Animals; Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Para | 1988 |
Field trials of praziquantel and oxamniquine for the treatment of schistosomiasis mansoni in Burundi.
Topics: Adult; Burundi; Clinical Trials as Topic; Feces; Humans; Nitroquinolines; Oxamniquine; Parasite Egg | 1987 |
Praziquantel and oltipraz: the treatment of schoolchildren infected with Schistosoma mansoni and/or Schistosoma haematobium in Gezira, Sudan.
Topics: Child; Female; Humans; Male; Parasite Egg Count; Praziquantel; Pyrazines; Random Allocation; Recurre | 1988 |
Cure rates and egg reduction in treatment of intestinal schistosomiasis with oxamniquine and praziquantel in Maniema, Zaire.
Topics: Adolescent; Adult; Child; Democratic Republic of the Congo; Feces; Humans; Nitroquinolines; Oxamniqu | 1988 |
Comparison between the efficacy of oxamniquine and praziquantel in the treatment of Schistosoma mansoni infections on a sugar estate in Ethiopia.
Topics: Adolescent; Adult; Drug Administration Schedule; Drug Evaluation; Drug Tolerance; Ethiopia; Female; | 1988 |
A three year follow-up of chemotherapy with praziquantel in a rural Zambian community endemic for schistosomiasis mansoni.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Female; Follow-Up Studies; Hum | 1988 |
707 other studies available for praziquantel and Schistosoma mansoni Infection
| Article | Year |
|---|---|
In vitro activities of trioxaquines against Schistosoma mansoni.
Topics: Aminoquinolines; Animals; Heterocyclic Compounds; Larva; Mice; Parasitic Sensitivity Tests; Schistos | 2009 |
Identification of antischistosomal leads by evaluating bridged 1,2,4,5-tetraoxanes, alphaperoxides, and tricyclic monoperoxides.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Chronic Disease; Female; Heme; Hemin; Heterocyclic | 2012 |
Design and synthesis of molecular probes for the determination of the target of the anthelmintic drug praziquantel.
Topics: Animals; Anthelmintics; Chromatography, Supercritical Fluid; Crystallography, X-Ray; Dose-Response R | 2014 |
Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis.
Topics: Animals; Dose-Response Relationship, Drug; Drug Delivery Systems; Helminth Proteins; Histone Deacety | 2016 |
SAR of a new antischistosomal urea carboxylic acid.
Topics: Animals; Carboxylic Acids; Half-Life; Humans; Mice; Microsomes, Liver; Schistosoma mansoni; Schistos | 2018 |
The discovery of a novel series of compounds with single-dose efficacy against juvenile and adult Schistosoma species.
Topics: Animals; Drug Administration Schedule; Drug Discovery; Female; Humans; Male; Mice; Praziquantel; Sch | 2021 |
Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation.
Topics: Animals; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Humans; Molecular Struct | 2021 |
Optimal single sampling time-point for monitoring of praziquantel exposure in children.
Topics: Administration, Oral; Adolescent; Animals; Anthelmintics; Biological Availability; Blood Specimen Co | 2021 |
Intestinal schistosomiasis among schoolchildren in Sana'a Governorate, Yemen: Prevalence, associated factors and its effect on nutritional status and anemia.
Topics: Adolescent; Anthelmintics; Child; Feces; Female; Growth Disorders; Humans; Male; Mass Drug Administr | 2021 |
Residence Time, Water Contact, and Age-driven Schistosoma mansoni Infection in Hotspot Communities in Uganda.
Topics: Adolescent; Adult; Age Factors; Anthelmintics; Child; Child, Preschool; Female; Humans; Infant; Lake | 2021 |
Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel.
Topics: Animals; Anthelmintics; Calcium; Drug Evaluation, Preclinical; Female; Helminth Proteins; Humans; Ma | 2021 |
Evaluation of the Point-of-Care Circulating Cathodic Antigen Assay for Monitoring Mass Drug Administration in a Schistosoma mansoni Control Program in Western Kenya.
Topics: Animals; Anthelmintics; Antigens, Helminth; Feces; Humans; Kenya; Mass Drug Administration; Point-of | 2021 |
Schistosomiasis mansoni: A new therapeutic target for ubiquinol, a natural inhibitor of neutral magnesium-dependent sphingomyelinase in murine model.
Topics: Animals; Disease Models, Animal; Female; Magnesium; Mice; Pharmaceutical Preparations; Praziquantel; | 2022 |
Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae.
Topics: Adolescent; Adult; Amino Acid Sequence; Animals; Anthelmintics; Antibodies, Helminth; Cercaria; Chil | 2021 |
The anticancer drug imatinib induces autophagy in Schistosoma mansoni.
Topics: Animals; Antineoplastic Agents; Autophagy; Imatinib Mesylate; Praziquantel; Schistosoma mansoni; Sch | 2022 |
Pyrazoline derivatives as promising novel antischistosomal agents.
Topics: Animals; Antiparasitic Agents; Chalcones; Chemistry, Pharmaceutical; Chlorocebus aethiops; Computer | 2021 |
Resolution of systemic complications in Schistosoma mansoni-infected mice by concomitant treatment with praziquantel and Schisandrin B.
Topics: Animals; Anthelmintics; Cyclooctanes; Lignans; Mice; Polycyclic Compounds; Praziquantel; Schistosoma | 2022 |
Genetic analysis of praziquantel response in schistosome parasites implicates a transient receptor potential channel.
Topics: Animals; Anthelmintics; Genome-Wide Association Study; Parasites; Praziquantel; Schistosomiasis mans | 2021 |
Schistosome TRPML channels play a role in neuromuscular activity and tegumental integrity.
Topics: Animals; Anthelmintics; Endosomes; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Trans | 2022 |
Dandelion (Taraxacum officinale) Improves the Therapeutic Efficiency of Praziquantel in Experimental Schistosomiasis.
Topics: Animals; Anthelmintics; Granuloma; Liver; Liver Diseases; Mice; Plant Extracts; Praziquantel; Schist | 2022 |
Determining the optimal strategies to achieve elimination of transmission for Schistosoma mansoni.
Topics: Animals; Anthelmintics; Humans; Mass Drug Administration; Praziquantel; Prevalence; Schistosoma mans | 2022 |
Potentiality of curcumin on ISHAK scoring system and the expressions of BAX, IL-17A, and EGF in the treatment ofSchistosoma mansoni infection using Swiss albino mice.
Topics: Animals; Anthelmintics; bcl-2-Associated X Protein; Curcumin; Epidermal Growth Factor; Granuloma; In | 2022 |
A genetic TRP down the channel to praziquantel resistance.
Topics: Animals; Anthelmintics; Drug Resistance; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni | 2022 |
Pathological and immunological evaluation of different regimens of praziquantel treatment in a mouse model of Schistosoma mansoni infection.
Topics: Animals; Anthelmintics; Disease Models, Animal; Granuloma; Mice; Praziquantel; Schistosoma mansoni; | 2022 |
Schistosomicidal and hepatoprotective activity of gamma-aminobutyric acid (GABA) alone or combined with praziquantel against Schistosoma mansoni infection in murine model.
Topics: Animals; Anthelmintics; Disease Models, Animal; gamma-Aminobutyric Acid; Liver; Mice; Praziquantel; | 2022 |
Oncolytic Myxoma virus infects and damages the tegument of the human parasitic flatworm Schistosoma mansoni.
Topics: Animals; Anthelmintics; Female; Humans; Male; Mammals; Myxoma virus; Oncolytic Viruses; Praziquantel | 2022 |
The prophylactic and anti-fibrotic activity of phthalimido-thiazole derivatives in schistosomiasis mansoni.
Topics: Animals; Praziquantel; Schistosoma mansoni; Schistosomiasis; Schistosomiasis mansoni; Thiazoles | 2022 |
Use of wogonin as a cooperative drug with praziquantel to better combat schistosomiasis.
Topics: Animals; Anthelmintics; Flavanones; Liver; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis; | 2022 |
Itraconazole, a cytochrome P450 inhibitor, enhanced the efficacy of praziquantel against Schistosoma mansoni infection and alleviated liver injury in mice.
Topics: Animals; Anthelmintics; Itraconazole; Liver; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasi | 2022 |
The Effect of Different Formulations of Praziquantel in Reducing Worms in the Prepatent Period of Schistosomiasis in Murine Models.
Topics: Animals; Disease Models, Animal; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis; Schistoso | 2022 |
Alternate-day fasting, a high-sucrose/caloric diet and praziquantel treatment influence biochemical and behavioral parameters during Schistosoma mansoni infection in male BALB/c mice.
Topics: Animals; Anthelmintics; Fasting; Glucose; Granuloma; Liver; Male; Mice; Mice, Inbred BALB C; Praziqu | 2022 |
Efficacy of Praziquantel Treatment and
Topics: Animals; Anthelmintics; Child; Child, Preschool; Cross-Sectional Studies; Ethiopia; Feces; Humans; P | 2022 |
Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection.
Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Calcium; Disease Models, Animal; Iron; Liver; Maln | 2022 |
Genome-wide analysis of Schistosoma mansoni reveals limited population structure and possible praziquantel drug selection pressure within Ugandan hot-spot communities.
Topics: Adult; Animals; Anthelmintics; Child; Humans; Pharmaceutical Preparations; Praziquantel; Schistosoma | 2022 |
Anti-inflammatory, antioxidant, anti-fibrotic and schistosomicidal properties of plumbagin in murine schistosomiasis.
Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Antioxidants; Catalase; Female; Granuloma; Immunog | 2022 |
Synthesis, in vitro schistosomicidal activity and ultrastructural alterations caused by thiosemicarbazones and thiazolidinones against juvenile and adult Schistosoma mansoni worms (Sambon, 1907).
Topics: Animals; Chlorocebus aethiops; Female; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; S | 2022 |
Parasitological and histopathological studies to the effect of aqueous extract of Moringa oleifera Lam. leaves combined with praziquantel therapy in modulating the liver and spleen damage induced by Schistosoma mansoni to male mice.
Topics: Animals; Anthelmintics; Liver; Male; Mice; Moringa oleifera; Praziquantel; Schistosoma mansoni; Schi | 2023 |
The role of environmental enteric dysfunction in the pathogenesis of Schistosoma mansoni-associated morbidity in school-aged children.
Topics: Animals; Anthelmintics; Child; Fatty Acids; Humans; Insulin-Like Growth Factor I; Insulins; Lipopoly | 2022 |
Role of IL-17A in enhancing liver fibrosis induced by TGF-β1 and IL-13 in Schistosoma mansoni infected mice.
Topics: Animals; Antibodies, Monoclonal; Case-Control Studies; Cytokines; Eosine Yellowish-(YS); Female; Hem | 2022 |
Fine-scale mapping of Schistosoma mansoni infections and infection intensities in sub-districts of Makenene in the Centre region of Cameroon.
Topics: Animals; Antigens, Helminth; Cameroon; Child; Feces; Humans; Praziquantel; Prevalence; Schistosoma m | 2022 |
Evaluation of faecal lactoferrin as a morbidity biomarker in Schistosoma mansoni infection.
Topics: Adolescent; Adult; Animals; Biomarkers; Child; Child, Preschool; Cross-Sectional Studies; Feces; Hum | 2022 |
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice.
Topics: Animals; Female; Humans; Infant; Male; Mice; Praziquantel; Schistosoma haematobium; Schistosoma japo | 2022 |
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice.
Topics: Animals; Female; Humans; Infant; Male; Mice; Praziquantel; Schistosoma haematobium; Schistosoma japo | 2022 |
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice.
Topics: Animals; Female; Humans; Infant; Male; Mice; Praziquantel; Schistosoma haematobium; Schistosoma japo | 2022 |
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice.
Topics: Animals; Female; Humans; Infant; Male; Mice; Praziquantel; Schistosoma haematobium; Schistosoma japo | 2022 |
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice.
Topics: Animals; Female; Humans; Infant; Male; Mice; Praziquantel; Schistosoma haematobium; Schistosoma japo | 2022 |
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice.
Topics: Animals; Female; Humans; Infant; Male; Mice; Praziquantel; Schistosoma haematobium; Schistosoma japo | 2022 |
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice.
Topics: Animals; Female; Humans; Infant; Male; Mice; Praziquantel; Schistosoma haematobium; Schistosoma japo | 2022 |
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice.
Topics: Animals; Female; Humans; Infant; Male; Mice; Praziquantel; Schistosoma haematobium; Schistosoma japo | 2022 |
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice.
Topics: Animals; Female; Humans; Infant; Male; Mice; Praziquantel; Schistosoma haematobium; Schistosoma japo | 2022 |
Effects of Schistosoma mansoni and praziquantel treatment on the lower gastrointestinal mucosa: A cohort study in Tanzania.
Topics: Adult; Animals; Anthelmintics; Cohort Studies; Humans; Mucous Membrane; Praziquantel; Prospective St | 2023 |
Effects of Schistosoma mansoni and praziquantel treatment on the lower gastrointestinal mucosa: A cohort study in Tanzania.
Topics: Adult; Animals; Anthelmintics; Cohort Studies; Humans; Mucous Membrane; Praziquantel; Prospective St | 2023 |
Effects of Schistosoma mansoni and praziquantel treatment on the lower gastrointestinal mucosa: A cohort study in Tanzania.
Topics: Adult; Animals; Anthelmintics; Cohort Studies; Humans; Mucous Membrane; Praziquantel; Prospective St | 2023 |
Effects of Schistosoma mansoni and praziquantel treatment on the lower gastrointestinal mucosa: A cohort study in Tanzania.
Topics: Adult; Animals; Anthelmintics; Cohort Studies; Humans; Mucous Membrane; Praziquantel; Prospective St | 2023 |
Effects of Schistosoma mansoni and praziquantel treatment on the lower gastrointestinal mucosa: A cohort study in Tanzania.
Topics: Adult; Animals; Anthelmintics; Cohort Studies; Humans; Mucous Membrane; Praziquantel; Prospective St | 2023 |
Effects of Schistosoma mansoni and praziquantel treatment on the lower gastrointestinal mucosa: A cohort study in Tanzania.
Topics: Adult; Animals; Anthelmintics; Cohort Studies; Humans; Mucous Membrane; Praziquantel; Prospective St | 2023 |
Effects of Schistosoma mansoni and praziquantel treatment on the lower gastrointestinal mucosa: A cohort study in Tanzania.
Topics: Adult; Animals; Anthelmintics; Cohort Studies; Humans; Mucous Membrane; Praziquantel; Prospective St | 2023 |
Effects of Schistosoma mansoni and praziquantel treatment on the lower gastrointestinal mucosa: A cohort study in Tanzania.
Topics: Adult; Animals; Anthelmintics; Cohort Studies; Humans; Mucous Membrane; Praziquantel; Prospective St | 2023 |
Effects of Schistosoma mansoni and praziquantel treatment on the lower gastrointestinal mucosa: A cohort study in Tanzania.
Topics: Adult; Animals; Anthelmintics; Cohort Studies; Humans; Mucous Membrane; Praziquantel; Prospective St | 2023 |
Prevalence of Schistosoma mansoni infection among fishermen in Busega district, Tanzania.
Topics: Adult; Cross-Sectional Studies; Humans; Praziquantel; Prevalence; Schistosomiasis mansoni; Tanzania | 2022 |
Prevalence of Schistosoma mansoni infection among fishermen in Busega district, Tanzania.
Topics: Adult; Cross-Sectional Studies; Humans; Praziquantel; Prevalence; Schistosomiasis mansoni; Tanzania | 2022 |
Prevalence of Schistosoma mansoni infection among fishermen in Busega district, Tanzania.
Topics: Adult; Cross-Sectional Studies; Humans; Praziquantel; Prevalence; Schistosomiasis mansoni; Tanzania | 2022 |
Prevalence of Schistosoma mansoni infection among fishermen in Busega district, Tanzania.
Topics: Adult; Cross-Sectional Studies; Humans; Praziquantel; Prevalence; Schistosomiasis mansoni; Tanzania | 2022 |
Bioactivity of Trigonella foenum (Fenugreek) oil on immunological and biochemical response of Schistosoma mansoni infected mice.
Topics: Animals; Annexins; Humans; Liver; Male; Mice; Plant Oils; Praziquantel; Schistosoma mansoni; Schisto | 2023 |
Electrophysiological characterization of a schistosome transient receptor potential channel activated by praziquantel.
Topics: Animals; Anthelmintics; Humans; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Transien | 2023 |
Understanding perceptions of schistosomiasis and its control among highly endemic lakeshore communities in Mayuge, Uganda.
Topics: Drinking Water; Humans; Lakes; Praziquantel; Prevalence; Schistosomiasis; Schistosomiasis mansoni; U | 2023 |
Biochanin A in murine
Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Fibrosis; Inflammation; Liver; Mice; Oxidative Str | 2023 |
Subclinical signs of podocyte injury associated with Circulating Anodic Antigen (CAA) in Schistosoma mansoni-infected patients in Brazil.
Topics: Animals; Antigens, Helminth; Brazil; Humans; Inflammation; Podocytes; Praziquantel; Prevalence; Schi | 2023 |
Test-Treat-Track-Test-Treat Strategy for Control of Schistosomiasis in Two Low-Prevalence Villages in Northwestern Tanzania.
Topics: Animals; Anthelmintics; Child; Feces; Humans; Praziquantel; Prevalence; Schistosoma mansoni; Schisto | 2023 |
Antischistosomal effects of green and chemically synthesized silver nanoparticles: In vitro and in vivo murine model.
Topics: Animals; Anthelmintics; Disease Models, Animal; Granuloma; Metal Nanoparticles; Mice; Praziquantel; | 2023 |
Anti-angiogenic and anti-proliferative activity of ziziphus leaf extract as a novel potential therapeutic agent for reducing hepatic injury in experimental hamster schistosomiasis.
Topics: Animals; Anthelmintics; Antioxidants; Cricetinae; Granuloma; Ki-67 Antigen; Liver; Plant Extracts; P | 2023 |
Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis.
Topics: Animals; Anthelmintics; Combined Modality Therapy; Humans; Neglected Diseases; Oxamniquine; Praziqua | 2023 |
In vitro evaluation of the effect of galectins on Schistosoma mansoni motility.
Topics: Animals; Galectin 1; Galectins; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni | 2023 |
In vitro and In silico assessment of antischistosomal activities of ethanolic extract of Cornulacamonacantha.
Topics: Animals; Microscopy, Electron, Scanning; Molecular Docking Simulation; Praziquantel; Schistosoma man | 2023 |
Safety and infectivity of female cercariae in Schistosoma-naïve, healthy participants: a controlled human Schistosoma mansoni infection study.
Topics: Adult; Animals; Anthelmintics; Cytokines; Female; Healthy Volunteers; Humans; Male; Praziquantel; Sc | 2023 |
The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda.
Topics: Adolescent; Adult; Aged; Albendazole; Animals; Anthelmintics; Child; Child, Preschool; Community Hea | 2019 |
Intestinal parasitoses and schistosome infections among students with special reference to praziquantel efficacy in patients with schistosomosis in Hajjah governorate, Yemen
Topics: Animals; Child; Feces; Humans; Intestinal Diseases, Parasitic; Praziquantel; Prevalence; Schistosoma | 2019 |
Intestinal schistosomiasis of Ijinga Island, north-western Tanzania: prevalence, intensity of infection, hepatosplenic morbidities and their associated factors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anthelmintics; Child; Child, Preschool; Cross-S | 2019 |
Kaposi's sarcoma-associated herpesvirus seropositivity is associated with parasite infections in Ugandan fishing communities on Lake Victoria islands.
Topics: Adolescent; Adult; Aged; Albendazole; Animals; Antibodies, Helminth; Antigens, Helminth; Child; Chil | 2019 |
Assessment of the potential therapeutic effects of omeprazole in Schistosoma mansoni infected mice.
Topics: Animals; Drug Therapy, Combination; Granuloma; Liver Cirrhosis; Male; Mice; Omeprazole; Parasite Egg | 2019 |
Enhancement of the therapeutic efficacy of praziquantel in murine Schistosomiasis mansoni using silica nanocarrier.
Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Disease Models, Animal; Drug Carriers; Drug Delive | 2019 |
In vivo effect of essential oil of Mentha x villosa and its active compound against Schistosoma mansoni (Sambon, 1907).
Topics: Animals; Female; Mentha; Mice; Oils, Volatile; Praziquantel; Schistosoma mansoni; Schistosomiasis ma | 2020 |
Insufficiency of annual praziquantel treatment to control Schistosoma mansoni infections in adult women: A longitudinal cohort study in rural Tanzania.
Topics: Adult; Animals; Anthelmintics; Female; Humans; Incidence; Longitudinal Studies; Mass Drug Administra | 2019 |
The changing profile of schistosomiasis in a changing urban landscape.
Topics: Adolescent; Adult; Animals; Brazil; Child; Cohort Studies; Female; Humans; Longitudinal Studies; Mal | 2020 |
Transmission control of schistosomiasis mansoni in a low endemicity area through a single intervention with rigorous prospection of infected cases treated with praziquantel: evaluation after 7 years of intervention.
Topics: Adult; Animals; Biomphalaria; Cohort Studies; Female; Humans; Male; Parasite Egg Count; Polymerase C | 2019 |
Two-year longitudinal survey reveals high genetic diversity of Schistosoma mansoni with adult worms surviving praziquantel treatment at the start of mass drug administration in Uganda.
Topics: Animals; Anthelmintics; Child; Drug Resistance; Female; Genetic Variation; Genotype; Humans; Longitu | 2019 |
Factors associated with relevant knowledge of intestinal schistosomiasis and intention to participate in treatment campaigns: a cross sectional survey among school children at Ijinga Island on Lake Victoria, North-Western Tanzania.
Topics: Adolescent; Child; Child, Preschool; Cross-Sectional Studies; Female; Health Knowledge, Attitudes, P | 2019 |
The Protective Role of Toll-Like Receptor Agonist Monophosphoryl Lipid A Against Vaccinated Murine Schistosomiasis.
Topics: Adjuvants, Immunologic; Animals; Anthelmintics; Antigens, Helminth; Helminth Proteins; Lipid A; Male | 2020 |
Detecting Schistosoma mansoni infections among pre-school-aged children in southern Ghana: a diagnostic comparison of urine-CCA, real-time PCR and Kato-Katz assays.
Topics: Animals; Antigens, Helminth; Biological Assay; Body Fluids; Child, Preschool; Diagnostic Tests, Rout | 2020 |
Bevacizumab as a potential anti-angiogenic therapy in schistosomiasis: A double-edged, but adjustable weapon.
Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Chronic Disease; Granuloma; Liver Diseases; Male; Mic | 2020 |
Nationwide Remapping of
Topics: Adolescent; Anthelmintics; Antigens, Helminth; Child; Disease Eradication; Eggs; Feces; Female; Geog | 2020 |
Identification of transmission foci of Schistosoma mansoni: narrowing the intervention target from district to transmission focus in Ethiopia.
Topics: Adolescent; Animals; Anthelmintics; Child; Child, Preschool; Cross-Sectional Studies; Disease Transm | 2020 |
Screening of a Library of Recombinant Schistosoma mansoni Proteins With Sera From Murine and Human Controlled Infections Identifies Early Serological Markers.
Topics: Animals; Biomarkers; Humans; Male; Mammals; Mice; Praziquantel; Recombinant Proteins; Schistosoma ma | 2022 |
Evaluation of morbidity in Schistosoma mansoni-positive primary and secondary school children after four years of mass drug administration of praziquantel in western Kenya.
Topics: Adolescent; Animals; Child; Cross-Sectional Studies; Female; Humans; Kenya; Male; Mass Drug Administ | 2020 |
Evaluation of a rapid diagnostic test for Schistosoma mansoni infection based on the detection of circulating cathodic antigen in urine in Central Sudan.
Topics: Adolescent; Animals; Anthelmintics; Antigens, Helminth; Child; Child, Preschool; Clinical Laboratory | 2020 |
Evaluation of serum-based real-time PCR to detect Schistosoma mansoni infection before and after treatment.
Topics: Adult; Aged; Aged, 80 and over; Animals; Diagnostic Tests, Routine; Feces; Female; Humans; Male; Mid | 2020 |
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni.
Topics: Animals; Anthelmintics; Drug Resistance; Enzyme Inhibitors; Histone Demethylases; Microscopy, Electr | 2020 |
Does mass drug administration affect Schistosoma mansoni infection trends in West Dembia district, Northwest Ethiopia?
Topics: Adolescent; Adult; Animals; Anthelmintics; Child; Child, Preschool; Cross-Sectional Studies; Endemic | 2020 |
Characteristics of persistent hotspots of Schistosoma mansoni in western Côte d'Ivoire.
Topics: Animals; Anthelmintics; Bulinus; Chemoprevention; Child; Cote d'Ivoire; Cross-Sectional Studies; Dis | 2020 |
Therapeutic efficacy of a newly synthesized benzimidazole compound BTP-OH against murine schistosomiasis mansoni.
Topics: Animals; Benzimidazoles; Female; Liver; Male; Mice; Parasite Egg Count; Praziquantel; Schistosoma ma | 2020 |
Schistosomiasis Control in Nigeria: Moving Round the Circle?
Topics: Animals; Anthelmintics; Biomphalaria; Bulinus; Communicable Disease Control; Health Policy; Humans; | 2020 |
Evaluation of Praziquantel Effectivenss After Decades of Prolonged Use in an Endemic Area in Egypt.
Topics: Animals; Anthelmintics; Child; Egypt; Humans; Praziquantel; Schistosoma mansoni; Schistosomiasis man | 2021 |
Use of kinase inhibitors against schistosomes to improve and broaden praziquantel efficacy.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Female; Liver; Male; Mice; Parasite Egg | 2020 |
Prevalence and risk factors of Schistosoma mansoni infection among children under two years of age in Mbita, Western Kenya.
Topics: Anthelmintics; Female; Humans; Infant; Kenya; Male; Praziquantel; Prevalence; Risk Factors; Schistos | 2020 |
Liver damage in schistosomiasis is reduced by adipose tissue-derived stem cell therapy after praziquantel treatment.
Topics: Adipose Tissue; Animals; Cell- and Tissue-Based Therapy; Cytokines; Disease Models, Animal; Granulom | 2020 |
An outbreak of intestinal schistosomiasis, alongside increasing urogenital schistosomiasis prevalence, in primary school children on the shoreline of Lake Malawi, Mangochi District, Malawi.
Topics: Anthelmintics; Child; Cross-Sectional Studies; Disease Outbreaks; Humans; Lakes; Malawi; Morbidity; | 2020 |
Dynamics of serological responses to defined recombinant proteins during Schistosoma mansoni infection in mice before and after the treatment with praziquantel.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Female; Helminth Proteins; Immunog | 2020 |
Single oral fixed-dose praziquantel-miltefosine nanocombination for effective control of experimental schistosomiasis mansoni.
Topics: Administration, Oral; Animals; Disease Models, Animal; Drug Combinations; Drug Compounding; Female; | 2020 |
Evaluation of prophylactic efficacy and safety of praziquantel-miltefosine nanocombination in experimental Schistosomiasis mansoni.
Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Carriers; Drug Combinations; Granuloma; Lipids; | 2020 |
In vivo assessment of the antischistosomal activity of curcumin loaded nanoparticles versus praziquantel in the treatment of Schistosoma mansoni.
Topics: Animals; Anthelmintics; Curcumin; Disease Models, Animal; Drug Synergism; Female; Gold; Male; Metal | 2020 |
Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy.
Topics: Adult; Animals; Anthelmintics; Drug Monitoring; Female; Humans; Male; Metabolome; Mice, Inbred ICR; | 2020 |
Evaluation of the therapeutic efficacy of praziquantel against schistosomes in seven countries with ongoing large-scale deworming programs.
Topics: Animals; Anthelmintics; Brazil; Child; Ethiopia; Humans; Praziquantel; Schistosoma mansoni; Schistos | 2020 |
Antischistosomal properties of aurone derivatives against juvenile and adult worms of Schistosoma mansoni.
Topics: Animals; Benzofurans; Disease Models, Animal; Female; Flavonoids; Mice; Parasitic Sensitivity Tests; | 2021 |
In vitro and in vivo evaluation of cnicin from blessed thistle (Centaurea benedicta) and its inclusion complexes with cyclodextrins against Schistosoma mansoni.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Oral; Animals; beta-Cyclodextrins; Centaurea; Dis | 2021 |
Evaluating survey designs for targeting preventive chemotherapy against Schistosoma haematobium and Schistosoma mansoni across sub-Saharan Africa: a geostatistical analysis and modelling study.
Topics: Adolescent; Africa South of the Sahara; Anthelmintics; Chemoprevention; Child; Child, Preschool; Cos | 2020 |
Praziquantel treatment coverage among school age children against Schistosomiasis and associated factors in Ethiopia: a cross-sectional survey, 2019.
Topics: Adolescent; Age Factors; Animals; Anthelmintics; Child; Cross-Sectional Studies; Deglutition; Delive | 2020 |
Praziquantel pharmacotherapy reduces systemic osteopontin levels and liver collagen content in murine schistosomiasis mansoni.
Topics: Animals; Anthelmintics; Collagen; Liver; Mice; Osteopontin; Praziquantel; Schistosoma mansoni; Schis | 2021 |
Intestinal schistosomiasis among preschool and school-aged children in a rural setting near Alexandria: initiative for elimination.
Topics: Animals; Anthelmintics; Child; Child, Preschool; Egypt; Female; Humans; Infant; Male; Praziquantel; | 2021 |
Doxycycline aggravates granulomatous inflammation and lung microstructural remodeling induced by Schistosoma mansoni infection.
Topics: Airway Remodeling; Animals; Anthelmintics; Cytokines; Disease Models, Animal; Doxycycline; Granuloma | 2021 |
High Egg Reduction Rate but poor clearance of Circulating Cathodic Antigen three weeks after Praziquantel treatment among school children on Ijinga Island, north-western Tanzania.
Topics: Adolescent; Animals; Antigens, Helminth; Child; Child, Preschool; Feces; Female; Humans; Islands; Ki | 2021 |
Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure.
Topics: Animals; Anthelmintics; Female; Liver; Mice; Neglected Diseases; Praziquantel; Schistosoma mansoni; | 2021 |
Recurrent Hematochezia in a Returning Traveler.
Topics: Adult; Animals; Antiplatyhelmintic Agents; Gastrointestinal Hemorrhage; Humans; Male; Praziquantel; | 2021 |
Five-Year Follow-Up on the Prevalence and Intensity of Infections of Schistosoma mansoni in a Hard-to-Reach District of Madagascar.
Topics: Adolescent; Animals; Anthelmintics; Child; Child, Preschool; Chronic Disease; Female; Humans; Madaga | 2021 |
Patients with severe schistosomiasis mansoni in Ituri Province, Democratic Republic of the Congo.
Topics: Adult; Animals; Democratic Republic of the Congo; Feces; Female; Humans; Middle Aged; Praziquantel; | 2021 |
Effect of celecoxib against different developmental stages of experimental Schistosoma mansoni infection.
Topics: Administration, Oral; Animals; Anthelmintics; Apoptosis; Celecoxib; Disease Models, Animal; Female; | 2021 |
Validation of a human-serum-based in vitro growth method for drug screening on juvenile development stages of Schistosoma mansoni.
Topics: Animals; Anthelmintics; Drug Evaluation, Preclinical; Female; Humans; Larva; Mice; Praziquantel; Sch | 2021 |
In vitro and in vivo effects of P-MAPA immunomodulator on schistosomiasis.
Topics: Animals; Female; Granuloma; Humans; Immunologic Factors; Intestines; Linoleic Acids; Liver; Male; Mi | 2021 |
A Real-Time PCR Assay for the Diagnosis of Intestinal Schistosomiasis and Cure Assessment After the Treatment of Individuals With Low Parasite Burden.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anthelmintics; Child; Child, Preschool; Cross-S | 2020 |
Serine protease inhibitor, serpin, is a biomarker following Schistosoma mansoni re-infection in mice.
Topics: Animals; Anthelmintics; Biomarkers; Mice; Praziquantel; Reinfection; Schistosoma mansoni; Schistosom | 2021 |
Ginger (Zingiber Officinale)-derived nanoparticles in Schistosoma mansoni infected mice: Hepatoprotective and enhancer of etiological treatment.
Topics: Administration, Oral; Animals; Anthelmintics; Drug Therapy, Combination; Granuloma; Liver; Male; Mef | 2021 |
Antifibrotic and anthelminthic effect of casticin on Schistosoma mansoni-infected BALB/c mice.
Topics: Animals; Anthelmintics; Anti-Infective Agents; Flavonoids; Humans; Liver; Liver Cirrhosis; Mice; Mic | 2022 |
An adjuvant effect of Metformin as an anti-fibrotic agent when administered with the anti-schistosomal Praziquantel in Schistosoma mansoni infected mice.
Topics: Adjuvants, Pharmaceutic; Animals; Anthelmintics; Diabetes Mellitus, Type 2; Fibrosis; Granuloma; Mal | 2021 |
A 12-year follow-up of intestinal schistosomiasis in pre-school-aged children in Assoni Village, Eastern Senegal.
Topics: Child; Child, Preschool; Follow-Up Studies; Humans; Infant; Praziquantel; Prevalence; Schistosomiasi | 2021 |
Neurological impairment caused by Schistosoma mansoni systemic infection exhibits early features of idiopathic neurodegenerative disease.
Topics: Acetylcysteine; Animals; Anthelmintics; Astrocytes; Deferoxamine; Disease Models, Animal; Free Radic | 2021 |
Efficacy of Mebendazole and Praziquantel against Soil-Transmitted Helminths and
Topics: Adolescent; Animals; Child; Ethiopia; Female; Geography; Helminthiasis; Helminths; Humans; Male; Meb | 2021 |
Parasitological and Biochemical Efficacy of the Active Ingredients of
Topics: Animals; Antioxidants; Curcuma; Curcumin; Disease Models, Animal; Disulfides; DNA Fragmentation; Fem | 2021 |
Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration.
Topics: Animals; Child; Female; Humans; Male; Mass Drug Administration; Praziquantel; Schistosoma mansoni; S | 2021 |
The Brief Case: Benign Rectal Polyp with Schistosoma mansoni.
Topics: Adult; Animals; Anthelmintics; Anti-Bacterial Agents; Biopsy; Female; Helicobacter Infections; Histo | 2017 |
Closing the Brief Case: Benign Rectal Polyp with Schistosoma mansoni.
Topics: Adult; Animals; Anthelmintics; Anti-Bacterial Agents; Biopsy; Female; Helicobacter Infections; Histo | 2017 |
Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis.
Topics: Anilides; Animals; Cercaria; Disease Models, Animal; Drug Therapy, Combination; Egypt; Female; Hedge | 2017 |
Antischistosomal Activity of Pyrido[1,2-a]benzimidazole Derivatives and Correlation with Inhibition of β-Hematin Formation.
Topics: Animals; Benzimidazoles; Disease Models, Animal; Female; Hemeproteins; Inhibitory Concentration 50; | 2017 |
Artichoke leaf extract protects liver of Schistosoma mansoni infected mice through modulation of hepatic stellate cells recruitment.
Topics: Alanine Transaminase; Animals; Anthelmintics; Aspartate Aminotransferases; Cynara scolymus; Female; | 2017 |
An explorative analysis of process and formulation variables affecting comilling in a vibrational mill: The case of praziquantel.
Topics: Animals; Anthelmintics; Chemistry, Pharmaceutical; Crystallization; Drug Compounding; Drug Stability | 2017 |
Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study.
Topics: Animals; Drug Resistance; Female; Fertility; Host-Parasite Interactions; Life History Traits; Male; | 2017 |
Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection.
Topics: Animals; Anthelmintics; ATP-Binding Cassette Transporters; Disease Models, Animal; Drug Resistance; | 2017 |
Change in children's school behavior after mass administration of praziquantel for Schistosoma mansoni infection in endemic areas of western Kenya: A pilot study using the Behavioral Assessment System for Children (BASC-2).
Topics: Animals; Applied Behavior Analysis; Child; Child Behavior; Endemic Diseases; Female; Host-Parasite I | 2017 |
A comparative study on the anti-schistosomal and hepatoprotective effects of vinpocetine and isosorbide-5-mononitrate on Schistosoma mansoni-infected mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Egypt; Female; Isosorbid | 2017 |
Hepatosplenic schistosomiasis: playing hide-and-seek with an elusive parasite.
Topics: Abdominal Pain; Adult; Animals; Denmark; Eritrea; Humans; Liver Diseases, Parasitic; Male; Praziquan | 2017 |
Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model.
Topics: Animals; Anthelmintics; Chemoprevention; Chromatography, Liquid; Dexamethasone; Disease Models, Anim | 2017 |
Insulin growth factor inhibitor as a potential new anti-schistosoma drug: An in vivo experimental study.
Topics: Animals; Antigens, Helminth; Body Weight; Female; Glucose Transporter Type 4; Homeostasis; Insulin R | 2017 |
Perceptions about interventions to control schistosomiasis among the Lake Victoria island communities of Koome, Uganda.
Topics: Adult; Animals; Drinking Water; Feces; Female; Focus Groups; Health Knowledge, Attitudes, Practice; | 2017 |
Simvastatin exerts antifibrotic effect and potentiates the antischistosomal effects of praziquantel in a murine model: Role of IL10.
Topics: Animals; Anthelmintics; Antifibrinolytic Agents; Disease Models, Animal; Drug Therapy, Combination; | 2017 |
Anti-angiogenic and anti-lymphangiogenic role of praziquantel and artemether in experimental mansoniasis.
Topics: Animals; Artemether; Artemisinins; Female; Granuloma; Liver Diseases; Mice; Praziquantel; Schistosom | 2017 |
Paeoniflorin targets apoptosis and ameliorates fibrosis in murine schistosomiasis mansoni: A novel insight.
Topics: Actins; Animals; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Biomphalaria; Fe | 2017 |
Schistosoma mansoni: In vivo evaluation of Phyllanthus amarus hexanic and ethanolic extracts.
Topics: Animals; Anthelmintics; Biomphalaria; Colon, Ascending; Ethanol; Feces; Female; Gas Chromatography-M | 2017 |
A 38-year-old woman with zosteriform skin lesions.
Topics: Adult; Animals; Anthelmintics; Diagnosis, Differential; Female; Humans; Nucleic Acid Amplification T | 2017 |
[Radiculomyelopathy in schistosomiasis].
Topics: Adrenal Cortex Hormones; Adult; Animals; Anthelmintics; Eritrea; Europe; Humans; Male; Neuroschistos | 2018 |
Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme.
Topics: Animals; Anthelmintics; Child; Drug Resistance; Genetic Variation; Genotype; Humans; National Health | 2017 |
The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand.
Topics: Animals; Anthelmintics; Cell Line; Computer Simulation; Drug Partial Agonism; Female; Humans; Mesent | 2017 |
Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases.
Topics: Acetylcholinesterase; Animals; Biological Transport; Cholinesterase Inhibitors; Disease Models, Anim | 2017 |
Impact of treatment with a Protein Tyrosine Kinase Inhibitor (Genistein) on acute and chronic experimental Schistosoma mansoni infection.
Topics: Acute Disease; Animals; Anthelmintics; Biomphalaria; Chronic Disease; Collagen; Female; Genistein; G | 2018 |
[Clinical features of imported schistosomiasis mansoni in Beijing City：a report of 6 cases].
Topics: Animals; Antibodies, Helminth; Beijing; Humans; Immunoglobulin G; Praziquantel; Schistosoma mansoni; | 2017 |
Innovative methodology for point-of-care circulating cathodic antigen with rapid urine concentration for use in the field for detecting low Schistosoma mansoni infection and for control of cure with high accuracy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anthelmintics; Antigens, Helminth; Brazil; Chil | 2018 |
Evaluating a point-of-care circulating cathodic antigen test (POC-CCA) to detect Schistosoma mansoni infections in a low endemic area in north-eastern Brazil.
Topics: Adult; Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Brazil; Child; Enzyme-Linke | 2018 |
Impact of Four Years of Annual Mass Drug Administration on Prevalence and Intensity of Schistosomiasis among Primary and High School Children in Western Kenya: A Repeated Cross-Sectional Study.
Topics: Adolescent; Albendazole; Animals; Anthelmintics; Child; Cross-Sectional Studies; Female; Humans; Ken | 2018 |
Effect of four rounds of annual school-wide mass praziquantel treatment for schistosoma mansoni control on schistosome-specific immune responses.
Topics: Adolescent; Animals; Anthelmintics; Antibodies, Helminth; Child; Cross-Sectional Studies; Cytokines; | 2018 |
Comparing the performance of circulating cathodic antigen and Kato-Katz techniques in evaluating Schistosoma mansoni infection in areas with low prevalence in selected counties of Kenya: a cross-sectional study.
Topics: Adolescent; Animals; Antigens, Helminth; Child; Child, Preschool; Cross-Sectional Studies; Diagnosti | 2018 |
Schistosomicidal, antifibrotic and antioxidant effects of Cucurbita pepo L. seed oil and praziquantel combined treatment for Schistosoma mansoni infection in a mouse model.
Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Antioxidants; Cucurbita; Disease Models, Animal; D | 2019 |
Characterizing the Biochemical Response to Schistosoma mansoni Infection and Treatment with Praziquantel in Preschool and School Aged Children.
Topics: Case-Control Studies; Child; Child, Preschool; Dose-Response Relationship, Drug; Humans; Metabolome; | 2018 |
Antischistosomal and anti-inflammatory activity of garlic and allicin compared with that of praziquantel in vivo.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Cytokines; Disulfides; Female; Garlic; Immunohistoche | 2018 |
Effects of Callistemon citrinus aqueous extract on prepatent and patent infections with Schistosoma mansoni in experimentally infected mice.
Topics: Animals; Drug Therapy, Combination; Granuloma; Intestines; Liver; Male; Mice; Mice, Inbred BALB C; M | 2019 |
Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity.
Topics: Alkaloids; Animals; Cell Line; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Inbred BALB | 2018 |
Sm-p80-based vaccine trial in baboons: efficacy when mimicking natural conditions of chronic disease, praziquantel therapy, immunization, and Schistosoma mansoni re-encounter.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Chronic Disease; Female; Humans; M | 2018 |
Topics: Albendazole; Animals; Anthelmintics; Child; Cohort Studies; Cross-Sectional Studies; Feces; Female; | 2018 |
A single dose of the antineoplastics hydroxyurea or cisplatin has praziquantel-like effects on Schistosoma mansoni worms and host mouse liver.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Female; | 2018 |
Capacity gaps in health facilities for case management of intestinal schistosomiasis and soil-transmitted helminthiasis in Burundi.
Topics: Adolescent; Adult; Albendazole; Animals; Anthelmintics; Burundi; Case Management; Child; Endemic Dis | 2018 |
Efficacy of single dose albendazole and praziquantel drugs among helminth-infected school children at Rural Bahir Dar, northwest Ethiopia.
Topics: Adolescent; Albendazole; Animals; Anthelmintics; Child; Cross-Sectional Studies; Ethiopia; Feces; Fe | 2018 |
Praziquantel-lipid nanocapsules: an oral nanotherapeutic with potential
Topics: Administration, Oral; Animals; Biological Availability; Cell Death; Dose-Response Relationship, Drug | 2018 |
Schistosomiasis (Bilharziasis) ova: An incidental finding in testicular tissue of an obstructive azoospermic man.
Topics: Adult; Animals; Azoospermia; Fertility Preservation; Granuloma, Foreign-Body; Humans; Incidental Fin | 2018 |
IMMUNOPROTECTION OF SOLUBLE EGG ANTIGENS AND PRAZIQUANTEL IN CHALLENGED MURINE SCHISTOSOMIASIS MANSONI.
Topics: Administration, Oral; Animals; Anthelmintics; Antigens, Helminth; Biomphalaria; Cytokines; Feces; Fe | 2017 |
Schistosoma mansoni schistosomula antigens induce Th1/Pro-inflammatory cytokine responses.
Topics: Animals; Anthelmintics; Antigens, Helminth; Cytokines; Female; Humans; Immunity, Cellular; Larva; Le | 2018 |
Antibody responses to Schistosoma mansoni schistosomula antigens.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Antibody Formation; Antigens, Helminth; Enzyme-Linked | 2018 |
Sensitivity of the Point-of-Care Circulating Cathodic Antigen Urine Cassette Test for Diagnosis of
Topics: Adolescent; Animals; Anthelmintics; Antigens, Helminth; Child; Cote d'Ivoire; Cross-Sectional Studie | 2018 |
Paeoniflorin in experimental BALB/c mansoniasis: A novel anti-angiogenic therapy.
Topics: Actins; Angiogenesis Inhibitors; Animals; Anthelmintics; Antigens, CD34; Artemether; Down-Regulation | 2019 |
Niosomes for enhanced activity of praziquantel against Schistosoma mansoni: in vivo and in vitro evaluation.
Topics: Animals; Biological Availability; Female; Humans; Intestines; Liposomes; Liver Diseases; Male; Mice; | 2019 |
Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni.
Topics: Animals; Anthelmintics; Computational Biology; Drug Delivery Systems; Drug Discovery; Epigenesis, Ge | 2018 |
[Etiological diagnosis of pulmonary hypertension: A cause of difficult diagnosis].
Topics: Adolescent; Animals; Diagnosis, Differential; Epoprostenol; Hepatitis B; Humans; Hypertension, Porta | 2019 |
TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling.
Topics: Administration, Oral; Animals; Arylsulfonates; Disease Models, Animal; Drug Discovery; Female; Liver | 2018 |
Transcriptomic analysis of reduced sensitivity to praziquantel in Schistosoma mansoni.
Topics: Animals; Anthelmintics; Drug Resistance; Gene Expression Profiling; Helminth Proteins; Humans; Prazi | 2019 |
A novel cell-free method to culture Schistosoma mansoni from cercariae to juvenile worm stages for in vitro drug testing.
Topics: Animals; Artemether; Cercaria; Culture Media, Serum-Free; Drug Evaluation, Preclinical; Humans; Mefl | 2019 |
Immunization with adult
Topics: Animals; Anthelmintics; Antibodies, Helminth; Female; Helminth Proteins; Humans; Immunization; Inter | 2019 |
In vitro schistosomicidal activity of tamoxifen and its effectiveness in a murine model of schistosomiasis at a single dose.
Topics: Animals; Disease Models, Animal; Drug Resistance; Feces; Female; Male; Mice; Mice, Inbred BALB C; Pr | 2019 |
Restaging Pulmonary Schistosomiasis.
Topics: Animals; Anthelmintics; Female; Humans; Lung; Lung Diseases, Parasitic; Male; Praziquantel; Schistos | 2019 |
Schistosoma mansoni infection among preschool age children attending Erer Health Center, Ethiopia and the response rate to praziquantel.
Topics: Animals; Anthelmintics; Child; Child, Preschool; Ethiopia; Feces; Female; Humans; Longitudinal Studi | 2019 |
Evaluation of the schistosomicidal, antioxidant and anti-inflammatory activities of the ethyl acetate fraction from Ozoroa pulcherrima Schweinf. Roots on Schistosoma mansoni-induced liver pathology in mice and its phytochemical characterization.
Topics: Anacardiaceae; Animals; Anti-Infective Agents; Antioxidants; Chemical and Drug Induced Liver Injury; | 2019 |
Schistosomiasis and associated iron-deficiency anaemia presenting decades after immigration from sub-Saharan Africa.
Topics: Adenoma; Administration, Oral; Africa South of the Sahara; Aged; Anemia, Iron-Deficiency; Animals; A | 2019 |
Testing the Infection Prevalence of
Topics: Adolescent; Animals; Child; Cross-Sectional Studies; DNA, Helminth; Feces; Humans; Mass Drug Adminis | 2019 |
A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection.
Topics: Animals; Biological Availability; Drug Carriers; Lipids; Male; Mice; Nanoparticles; Praziquantel; Sc | 2019 |
Combined chemotherapy manifest less severe immunopathology effects in helminth-protozoa comorbidity.
Topics: Analysis of Variance; Animals; Anthelmintics; Antimony Sodium Gluconate; Antiprotozoal Agents; Chemo | 2019 |
Primary infertility associated with schitosoma mansoni: a case report from the Jos plateau, north central Nigeria.
Topics: Adult; Animals; Anthelmintics; Biopsy; Humans; Infertility, Male; Male; Nigeria; Praziquantel; Schis | 2012 |
An outbreak of acute Schistosoma mansoni Schistosomiasis in a nonendemic area of Brazil: a report on 50 cases, including 5 with severe clinical manifestations.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anthelmintics; Brazil; Case-Control Studies; Ch | 2013 |
Accuracy of urine circulating cathodic antigen test for the diagnosis of Schistosoma mansoni in preschool-aged children before and after treatment.
Topics: Animals; Anthelmintics; Antigens, Helminth; Child, Preschool; Clinical Laboratory Techniques; Cote d | 2013 |
Efficacy and side effects of praziquantel in the treatment of Schistosomiasis mansoni in schoolchildren in Shesha Kekele Elementary School, Wondo Genet, Southern Ethiopia.
Topics: Adolescent; Adult; Child; Cross-Sectional Studies; Ethiopia; Feces; Female; Humans; Male; Praziquant | 2012 |
Evaluation of urine-circulating cathodic antigen (Urine-CCA) cassette test for the detection of Schistosoma mansoni infection in areas of moderate prevalence in Ethiopia.
Topics: Animals; Anthelmintics; Antigens, Helminth; Child; Child, Preschool; Clinical Laboratory Techniques; | 2013 |
Uptake of preventive treatment for intestinal schistosomiasis among school children in Jinja district, Uganda: a cross sectional study.
Topics: Anthelmintics; Child; Confidence Intervals; Cross-Sectional Studies; Female; Humans; Male; Odds Rati | 2013 |
Association between CD4+ T-lymphocyte counts and fecal excretion of Schistosoma mansoni eggs in patients coinfected with S. mansoni and human immunodeficiency virus before and after initiation of antiretroviral therapy.
Topics: Adult; Animals; Anthelmintics; Anti-HIV Agents; CD4 Lymphocyte Count; Coinfection; Feces; HIV Infect | 2013 |
Regular treatments of praziquantel do not impact on the genetic make-up of Schistosoma mansoni in Northern Senegal.
Topics: Animals; Anthelmintics; Cluster Analysis; Drug Resistance; Feces; Genetic Variation; Genotype; Human | 2013 |
Triple worm infestation in an HIV-infected patient.
Topics: Adult; AIDS-Related Opportunistic Infections; Albendazole; Animals; Anthelmintics; Appendicitis; Dic | 2013 |
Efficacy of praziquantel and reinfection patterns in single and mixed infection foci for intestinal and urogenital schistosomiasis in Cameroon.
Topics: Adolescent; Animals; Anthelmintics; Biomphalaria; Bulinus; Cameroon; Child; Coinfection; Female; Fol | 2013 |
In vivo schistosomicidal activity of three novels 8-hydroxyquinoline derivatives against adult and immature worms of Schistosoma mansoni.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Granuloma; Humans; Liver; Male; Mice; Oxyquinolin | 2013 |
Liposomal-praziquantel: efficacy against Schistosoma mansoni in a preclinical assay.
Topics: Animals; Anthelmintics; Biological Availability; Disease Models, Animal; Drug Carriers; Drug Evaluat | 2013 |
Telmisartan, an AT1 receptor blocker and a PPAR gamma activator, alleviates liver fibrosis induced experimentally by Schistosoma mansoni infection.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anthelmintics; Benzimidazoles; Benzoates; Disease | 2013 |
Combination therapy using Pentostam and Praziquantel improves lesion healing and parasite resolution in BALB/c mice co-infected with Leishmania major and Schistosoma mansoni.
Topics: Animals; Anthelmintics; Antimony Sodium Gluconate; Coinfection; Drug Therapy, Combination; Leishmani | 2013 |
Dihydroartemisinin: a new story of an old drug against Schistosoma mansoni infection.
Topics: Animals; Artemisinins; Female; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Sch | 2014 |
Ultrastructural alterations in adult Schistosoma mansoni, harbored in non-antihelminthic treated and low-inflammatory mice by transmission electron microscopy (TEM).
Topics: Animals; Artemether; Artemisinins; Disease Susceptibility; Female; Male; Mice; Mice, Inbred Strains; | 2014 |
Monocyte chemotactic protein-1 (MCP-1) in patients with chronic schistosomiasis mansoni: evidences of subclinical renal inflammation.
Topics: Adolescent; Adult; Albuminuria; Animals; Anthelmintics; Biomarkers; Chemokine CCL2; Child; Child, Pr | 2013 |
Schistogram changes after administration of antischistosomal drugs in mice at the early phase of Schistosoma mansoni infection.
Topics: Animals; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Mice; Oxamniquine; Parasite Eg | 2013 |
Assessment of quality of life as a tool for measuring morbidity due to Schistosoma mansoni infection and the impact of treatment.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albendazole; Animals; Anthropometry; Feces; Female; Foll | 2014 |
Increasing teacher motivation and supervision is an important but not sufficient strategy for improving praziquantel uptake in Schistosoma mansoni control programs: serial cross sectional surveys in Uganda.
Topics: Adolescent; Animals; Anthelmintics; Child; Cross-Sectional Studies; Faculty; Female; Follow-Up Studi | 2013 |
New insights into the molecular epidemiology and population genetics of Schistosoma mansoni in Ugandan pre-school children and mothers.
Topics: Africa; Animals; Anthelmintics; Child, Preschool; Electron Transport Complex IV; Family Health; Fema | 2013 |
Posttreatment changes in cytokines induced by Schistosoma mansoni egg and worm antigens: dissociation of immunity- and morbidity-associated type 2 responses.
Topics: Adolescent; Animals; Antigens, Helminth; Child; Cytokines; Female; Gene Expression Regulation; Human | 2014 |
Praziquantel treatment decreases Schistosoma mansoni genetic diversity in experimental infections.
Topics: Animals; Anthelmintics; Drug Resistance; Female; Genetic Variation; Male; Mice; Microsatellite Repea | 2013 |
Overview on cysteine protease inhibitors as chemotherapy for Schistosomiasis mansoni in mice and also its effect on the parasitological and immunological profile.
Topics: Animals; Cysteine Proteinase Inhibitors; Disease Models, Animal; Granuloma; Intestines; Liver; Male; | 2013 |
Anthelmintic activity in vitro and in vivo of Baccharis trimera (Less) DC against immature and adult worms of Schistosoma mansoni.
Topics: Animals; Anthelmintics; Baccharis; Chlorocebus aethiops; Feces; Female; Liver; Male; Mice; Mice, Inb | 2014 |
Differential expression of anti-glycan antibodies in schistosome-infected humans, rhesus monkeys and mice.
Topics: Adult; Animals; Antibodies, Helminth; Epitopes; Humans; Immunoglobulin G; Lactose; Macaca mulatta; M | 2014 |
Understanding low uptake of mass treatment for intestinal schistosomiasis among school children: a qualitative study in Jinja district, Uganda.
Topics: Adolescent; Child; Cross-Sectional Studies; Faculty; Female; Focus Groups; Humans; Interviews as Top | 2015 |
Immunological and parasitological parameters in Schistosoma mansoni-infected mice treated with crude extract from the leaves of Mentha x piperita L.
Topics: Animals; Cytokines; Female; Humans; Immunoglobulins; Intestines; Mentha piperita; Mice; Mice, Inbred | 2014 |
Suppression of basophil histamine release and other IgE-dependent responses in childhood Schistosoma mansoni/hookworm coinfection.
Topics: Adolescent; Albendazole; Anthelmintics; Child; Histamine; Hookworm Infections; Humans; Immunoglobuli | 2014 |
Bilharziasis cutanea tarda: a rare manifestation of schistosomiasis and ectopic presentation of late cutaneous disease.
Topics: Adult; Animals; Anthelmintics; Brazil; Female; Humans; Lakes; Praziquantel; Schistosoma mansoni; Sch | 2014 |
The use of microencapsulated hepatocytes transplantation reduces mortality and liver alterations in Schistosoma mansoni infected hamsters.
Topics: Animals; Cricetinae; Cyclosporine; Drug Compounding; Hepatocytes; Lipid Peroxidation; Liver; Oxidati | 2014 |
Activity of praziquantel enantiomers and main metabolites against Schistosoma mansoni.
Topics: Animals; Liver; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides | 2014 |
Endomyocardial fibrosis (EMF) in a Ugandan child with advanced hepatosplenic schistosomiasis: coincidence or connection?
Topics: Animals; Anthelmintics; Child; Endomyocardial Fibrosis; Feces; Humans; Liver Diseases; Male; Praziqu | 2014 |
The hepatoprotective activity of blue green algae in Schistosoma mansoni infected mice.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Anthelmintics; Aspartate Aminotransferases; Blo | 2014 |
Long-term effect of mass chemotherapy, transmission and risk factors for Schistosoma mansoni infection in very low endemic communities of Venezuela.
Topics: Adolescent; Adult; Animals; Child; Cross-Sectional Studies; Female; Humans; Male; Praziquantel; Prev | 2014 |
Sensitivity and specificity of multiple Kato-Katz thick smears and a circulating cathodic antigen test for Schistosoma mansoni diagnosis pre- and post-repeated-praziquantel treatment.
Topics: Animals; Anthelmintics; Antigens, Helminth; Child; Feces; Humans; Praziquantel; Schistosoma mansoni; | 2014 |
Propolis enhances the effectiveness of praziquantel in experimental schistosomiasis: biochemical and histopathological study.
Topics: Animals; Anti-Infective Agents; Blood Proteins; Drug Therapy, Combination; Glutathione; Granuloma; I | 2014 |
Bayesian risk mapping and model-based estimation of Schistosoma haematobium-Schistosoma mansoni co-distribution in Côte d'Ivoire.
Topics: Adolescent; Bayes Theorem; Child; Child, Preschool; Coinfection; Cote d'Ivoire; Cross-Sectional Stud | 2014 |
Efficacy of Synriam™, a new antimalarial combination of OZ277 and piperaquine, against different developmental stages of Schistosoma mansoni.
Topics: Adolescent; Animals; Antimalarials; Cricetinae; Disease Models, Animal; Drug Combinations; Heterocyc | 2015 |
Intestinal schistosomiasis associated with intussusception: a case report.
Topics: Anthelmintics; Cecal Diseases; Child; Humans; Ileal Diseases; Intussusception; Male; Praziquantel; S | 2011 |
Evaluation of a method for induction of praziquantel resistance in Schistosoma mansoni.
Topics: Animals; Anthelmintics; Drug Evaluation, Preclinical; Drug Resistance; Mice; Praziquantel; Schistoso | 2015 |
A new focus of schistosomiasis mansoni in Hayk town, northeastern Ethiopia.
Topics: Adolescent; Albendazole; Animals; Anthelmintics; Biomphalaria; Child; Child, Preschool; Cross-Sectio | 2015 |
Schistosomal appendicitis with portal hypertension.
Topics: Animals; Anthelmintics; Appendicitis; Female; Humans; Hypertension, Portal; Middle Aged; Praziquante | 2015 |
Morbidity associated with schistosomiasis before and after treatment in young children in Rusinga Island, western Kenya.
Topics: Age Distribution; Animals; Anthelmintics; Child; Child, Preschool; Cohort Studies; Cross-Sectional S | 2015 |
Transmission electron microscopic observations on ultrastructural alterations in Schistosoma mansoni adult worms recovered from C57BL/6 mice treated with radiation-attenuated vaccine and/or praziquantel in addition to passive immunization with normal and
Topics: Animals; Female; Humans; Immunization, Passive; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron | 2015 |
Uptake of mass drug administration programme for schistosomiasis control in Koome Islands, Central Uganda.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthelmintics; Cross-Sectional Studies; Endemic Diseases | 2015 |
Praziquantel in a clay nanoformulation shows more bioavailability and higher efficacy against murine Schistosoma mansoni infection.
Topics: Animals; Anthelmintics; Biological Availability; Male; Mice; Praziquantel; Schistosoma mansoni; Schi | 2015 |
Evaluation of parasitological and molecular techniques for the diagnosis and assessment of cure of schistosomiasis mansoni in a low transmission area.
Topics: Animals; Anthelmintics; Brazil; Endemic Diseases; Enzyme-Linked Immunosorbent Assay; Feces; Female; | 2015 |
A Case Report--Sonomorphological Changes in Hepatosplenic Schistosomiasis.
Topics: Adult; Developing Countries; Ethiopia; Germany; Humans; Hypertension, Portal; Liver; Liver Cirrhosis | 2015 |
Application in Europe of a urine-based rapid diagnostic test for confirmation of Schistosoma mansoni infection in migrants from endemic areas.
Topics: Adolescent; Animals; Anthelmintics; Antigens, Helminth; Biopsy; Clinical Laboratory Techniques; Erit | 2015 |
Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel Treatment.
Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Animals; Antibodies, Helminth; Antigens, Helminth; Chi | 2015 |
Tandem repeat recombinant proteins as potential antigens for the sero-diagnosis of Schistosoma mansoni infection.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Biomarkers; Disease Models, Animal | 2015 |
Can human schistosomiasis mansoni control be sustained in high-risk transmission foci in Egypt?
Topics: Adolescent; Adult; Anthelmintics; Child; Child, Preschool; Egypt; Feces; Female; Humans; Male; Odds | 2015 |
Effectiveness of hyperbaric oxygen for experimental treatment of schistosomiasis mansoni using praziquantel-free and encapsulated into liposomes: assay in adult worms and oviposition.
Topics: Animals; Anthelmintics; Colon; Drug Administration Schedule; Drug Carriers; Drug Evaluation, Preclin | 2015 |
The Role of Efflux Pumps in Schistosoma mansoni Praziquantel Resistant Phenotype.
Topics: Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Fami | 2015 |
Epidemiological Interactions between Urogenital and Intestinal Human Schistosomiasis in the Context of Praziquantel Treatment across Three West African Countries.
Topics: Animals; Anthelmintics; Coinfection; Female; Humans; Male; Praziquantel; Schistosomiasis haematobia; | 2015 |
Hepatobiliary and Pancreatic: Acute hepatitis in the setting of chronic Schistosoma mansoni infection and post-praziquantel therapy.
Topics: Acute Disease; Animals; Anthelmintics; Anti-Inflammatory Agents; Biopsy; Chronic Disease; Hepatitis; | 2016 |
The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development.
Topics: Animals; Cytochrome P-450 Enzyme System; Drug Resistance; Female; Helminth Proteins; Humans; Male; O | 2015 |
Myeloradicular Form of Neuroschistosomiasis in a Six-Year-Old Boy Infected With Schistosoma mansoni.
Topics: Anthelmintics; Child; Humans; Magnetic Resonance Imaging; Male; Neuroschistosomiasis; Praziquantel; | 2015 |
SCHISTOSOMA MANSONI INFECTION AND THE ASSOCIATED ANTIBODY IMMUNE RESPONSE AMONGST RESIDENTS OF KIGUNGU ENTEBBE, UGANDA.
Topics: Adolescent; Adult; Animals; Anthelmintics; Antibodies, Helminth; Child; Child, Preschool; Cohort Stu | 2012 |
Wharton's jelly-derived mesenchymal stem cells combined with praziquantel as a potential therapy for Schistosoma mansoni-induced liver fibrosis.
Topics: Animals; Cell- and Tissue-Based Therapy; Humans; Liver Cirrhosis; Mesenchymal Stem Cell Transplantat | 2016 |
Repeated praziquantel treatments remodel the genetic and spatial landscape of schistosomiasis risk and transmission.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anthelmintics; Brazil; Child; Child, Preschool; | 2016 |
Miltefosine lipid nanocapsules: Intersection of drug repurposing and nanotechnology for single dose oral treatment of pre-patent schistosomiasis mansoni.
Topics: Administration, Oral; Animals; Disease Models, Animal; Drug Repositioning; Granuloma; Liver; Mice; N | 2016 |
SCHISTOSOMICIDAL ACTIVITY OF THE CRUDE EXTRACT OF ARTOCARPUS LAKOOCHA.
Topics: Animals; Anthelmintics; Laos; Plant Extracts; Praziquantel; Schistosoma mansoni; Schistosomiasis man | 2016 |
[Peranal bleeding and elevated liver function tests in a 33‑year-old refugee from Nigeria].
Topics: Adult; Anthelmintics; Anus Diseases; Diagnosis, Differential; Hemorrhage; Humans; Liver Diseases; Li | 2016 |
Derivatives of biarylalkyl carboxylic acid induce pleiotropic phenotypes in adult Schistosoma mansoni in vitro.
Topics: Animals; Carboxylic Acids; Female; Humans; Male; Molecular Structure; Phenotype; Praziquantel; Schis | 2016 |
Discovery of Antischistosomal Drug Leads Based on Tetraazamacrocyclic Derivatives and Their Metal Complexes.
Topics: Animals; Cations, Divalent; Cercaria; Coordination Complexes; Drug Discovery; Female; Heterocyclic C | 2016 |
Dose-response relationship in Schistosoma mansoni juvenile and adult stages following limonin treatment in experimentally infected mice.
Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resist | 2016 |
Improvement of POC-CCA Interpretation by Using Lyophilization of Urine from Patients with Schistosoma mansoni Low Worm Burden: Towards an Elimination of Doubts about the Concept of Trace.
Topics: Albendazole; Animals; Anthelmintics; Antigens, Helminth; Feces; Freeze Drying; Glycoproteins; Helmin | 2016 |
LOW PREVALENCE OF INTESTINAL SCHISTOSOMIASIS AMONG FISHERFOLK LIVING ALONG THE RIVER NILE IN NORTH-WESTERN UGANDA: A BIOSOCIAL INVESTIGATION.
Topics: Adult; Anthelmintics; Communicable Disease Control; Female; Fisheries; Humans; Hygiene; Intestines; | 2016 |
Schistosomiasis Sustained Control Program in Ethnic Groups Around Ninefescha (Eastern Senegal).
Topics: Adolescent; Animals; Child; Child, Preschool; Ethnicity; Health Education; Health Promotion; Humans; | 2016 |
Reduced Efficacy of Praziquantel Against Schistosoma mansoni Is Associated With Multiple Rounds of Mass Drug Administration.
Topics: Animals; Child; Cross-Sectional Studies; Drug Resistance; Female; Humans; Male; Mass Drug Administra | 2016 |
Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris.
Topics: Animals; Anthelmintics; Asteraceae; Female; Humans; Male; Mice; Mice, Inbred BALB C; Microscopy, Ele | 2016 |
Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy.
Topics: Animals; Anthelmintics; Antigens, Helminth; Child; Child, Preschool; Feces; Female; Humans; Male; Pa | 2016 |
Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems.
Topics: Animals; Disease Models, Animal; Drug Resistance; Female; Genitalia; Half-Life; Humans; Life Cycle S | 2016 |
A 57-Year-Old Woman With a Cecal Mass.
Topics: Adenoma, Villous; Animals; Anthelmintics; Cecum; Colectomy; Female; Humans; Intestinal Neoplasms; Li | 2016 |
Development and evaluation of a Markov model to predict changes in schistosomiasis prevalence in response to praziquantel treatment: a case study of Schistosoma mansoni in Uganda and Mali.
Topics: Animals; Cross-Sectional Studies; Disease Management; Humans; Mali; Markov Chains; Models, Statistic | 2016 |
Prevalence of Schistosoma mansoni infection and the therapeutic efficacy of praziquantel among school children in Manna District, Jimma Zone, southwest Ethiopia.
Topics: Adolescent; Anthelmintics; Child; Cross-Sectional Studies; Ethiopia; Feces; Female; Humans; Male; Mi | 2016 |
Clinical Report: Schistosomiasis Exposure in U.S. Service Personnel During Whitewater Rafting on the Nile River in Jinja, Uganda.
Topics: Adult; Anthelmintics; Female; Fresh Water; Humans; Male; Military Personnel; Praziquantel; Rivers; S | 2016 |
Decline in transmission of schistosomiasis mansoni in Oman.
Topics: Adolescent; Animals; Anthelmintics; Child; Humans; Oman; Praziquantel; Prevalence; Schistosoma manso | 2016 |
Mapping of Schistosoma mansoni in the Nile Delta, Egypt: Assessment of the prevalence by the circulating cathodic antigen urine assay.
Topics: Adult; Animals; Anthelmintics; Antigens, Helminth; Child; Egypt; Female; Geographic Mapping; Humans; | 2017 |
Histological detection of Schistosoma mansoni infection in a mature cystic teratoma of the ovary.
Topics: Adult; Animals; Anthelmintics; Cyst Fluid; Female; Humans; Ovarian Neoplasms; Ovariectomy; Praziquan | 2017 |
Intestinal schistosomiasis in Uganda at high altitude (>1400 m): malacological and epidemiological surveys on Mount Elgon and in Fort Portal crater lakes reveal extra preventive chemotherapy needs.
Topics: Adolescent; Altitude; Animals; Anthelmintics; Child; Geographic Information Systems; Humans; Lakes; | 2017 |
Missed treatment opportunities for schistosomiasis mansoni, in an active programme for the treatment of urinary schistosomiasis in Plateau and Nasarawa states, Nigeria.
Topics: Adolescent; Animals; Anthelmintics; Child; Cross-Sectional Studies; Endemic Diseases; Feces; Female; | 2008 |
Response of Schistosoma mansoni isolates having different drug sensitivity to praziquantel over several life cycle passages with and without therapeutic pressure.
Topics: Animals; Anthelmintics; Biomphalaria; Female; Humans; Inhibitory Concentration 50; Male; Mice; Paras | 2008 |
Experimental schistosomal hepatitis: protective effect of coenzyme-Q10 against the state of oxidative stress.
Topics: Actins; Animals; Anthelmintics; Aryldialkylphosphatase; Biomphalaria; Carboxylic Ester Hydrolases; D | 2008 |
Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni.
Topics: Animals; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice | 2008 |
Two-year impact of single praziquantel treatment on infection in the national control programme on schistosomiasis in Burkina Faso.
Topics: Adolescent; Anthelmintics; Burkina Faso; Child; Cross-Sectional Studies; Female; Humans; Longitudina | 2008 |
Sequential analysis of helminth egg output in human stool samples following albendazole and praziquantel administration.
Topics: Adolescent; Albendazole; Animals; Anthelmintics; Child; Child, Preschool; Feces; Female; Hookworm In | 2009 |
Circulating CD23+ B cell subset correlates with the development of resistance to Schistosoma mansoni reinfection in occupationally exposed adults who have undergone multiple treatments.
Topics: Animals; Anthelmintics; B-Lymphocyte Subsets; Eosinophilia; Humans; Male; Occupational Exposure; Pra | 2009 |
Association of oxamniquine praziquantel and clonazepam in experimental Schistosomiasis mansoni.
Topics: Animals; Clonazepam; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Liver; Male; M | 2008 |
Impact of intense, longitudinal retreatment with praziquantel on cure rates of schistosomiasis mansoni in a cohort of occupationally exposed adults in western Kenya.
Topics: Adult; Animals; Anthelmintics; Drug Resistance; HIV Infections; Humans; Liver Diseases, Parasitic; L | 2009 |
Assessing the marginal error in diagnosis and cure of Schistosoma mansoni in areas of low endemicity using Percoll and PCR techniques.
Topics: Animals; Anthelmintics; Centrifugation, Density Gradient; Child; DNA, Protozoan; Egypt; False Negati | 2009 |
Gastro-intestinal symptoms associated with intense Schistosoma mansoni infection affect class-attentiveness of schoolchildren in Ethiopia.
Topics: Abdominal Pain; Adolescent; Albendazole; Animals; Anthelmintics; Attention; Child; Cross-Sectional S | 2009 |
Common cause of chronic diarrhea not to be forgotten.
Topics: Abdominal Pain; Adult; Animals; Biopsy, Needle; Chronic Disease; Colonoscopy; Diarrhea; Follow-Up St | 2009 |
Plasmodium yoelii: adverse outcome of non-lethal P. yoelii malaria during co-infection with Schistosoma mansoni in BALB/c mouse model.
Topics: Anemia; Animals; Anthelmintics; Disease Models, Animal; Female; Hematocrit; Hepatomegaly; Malaria; M | 2009 |
Schistosoma mansoni: effect of dietary zinc supplement on egg granuloma in Swiss mice treated with praziqantel.
Topics: Animals; Anthelmintics; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Dietary Supplements; Dr | 2009 |
Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility.
Topics: Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance; Eg | 2009 |
Improvement of the oral praziquantel anthelmintic effect by cyclodextrin complexation.
Topics: Administration, Oral; Animals; Anthelmintics; beta-Cyclodextrins; Biological Availability; Calorimet | 2010 |
[Sciatica after return from Mali: case report of schistosomal myelopathy].
Topics: Adult; Anthelmintics; Diagnosis, Differential; Glucocorticoids; Humans; Male; Mali; Methylprednisolo | 2009 |
Nodular lung schistosomiais lesions after chemotherapy for dysgerminoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dysgerminoma; Eosinophilia; Female; Humans; L | 2009 |
Effect of praziquantel administration on hepatic stereology of mice infected with Schistosoma mansoni and fed a low-protein diet.
Topics: Animals; Anthelmintics; Diet, Protein-Restricted; Female; Hepatocytes; Liver; Liver Cirrhosis; Mice; | 2009 |
[Neuroschistosomiasis; an unexpected finding in a Dutch woman].
Topics: Aged; Animals; Anthelmintics; Brazil; Feces; Female; Humans; Magnetic Resonance Imaging; Netherlands | 2009 |
Parasitological and histo-pathological studies on schistosomiasis mansoni infected mice and treated with praziquatel and/or oltipraz.
Topics: Animals; Drug Therapy, Combination; Humans; Liver; Male; Mice; Parasite Egg Count; Praziquantel; Pyr | 2009 |
Elimination of helminth infection restores HIV-1C vaccine-specific T cell responses independent of helminth-induced IL-10.
Topics: AIDS Vaccines; Animals; Anthelmintics; Cytokines; Female; HIV-1; Mice; Mice, Inbred BALB C; Praziqua | 2010 |
Asymptomatic colon adenoma associated with Schistosoma mansoni.
Topics: Adenoma; Anthelmintics; Female; Humans; Middle Aged; Praziquantel; Schistosomiasis mansoni; Sigmoid | 2010 |
Factors controlling the effect of praziquantel on liver fibrosis in Schistosoma mansoni-infected patients.
Topics: Adolescent; Adult; Age Factors; Animals; Anthelmintics; Child; Child, Preschool; Disease Progression | 2010 |
Influence of exposure history on the immunology and development of resistance to human Schistosomiasis mansoni.
Topics: Adult; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Cohort Studies; Humans; Immunoglobulin | 2010 |
Schistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantel.
Topics: Animals; Anthelmintics; Drug Resistance, Multiple; Female; Gene Expression Regulation, Developmental | 2010 |
Intestinal schistosomiasis caused by both Schistosoma intercalatum and Schistosoma mansoni.
Topics: Adult; Amlodipine; Animals; Biphenyl Compounds; Colon, Sigmoid; Colon, Transverse; Colonoscopy; Hist | 2010 |
An unusual case of diarrhea.
Topics: Adult; Animals; Anthelmintics; Biopsy; Colonoscopy; Diagnosis, Differential; Diarrhea; Female; Follo | 2010 |
Is indeterminate colitis really indeterminate?
Topics: Acute Disease; Adult; Anthelmintics; Colitis; Humans; Male; Praziquantel; Schistosomiasis mansoni; S | 2010 |
Increases in levels of schistosome-specific immunoglobulin E and CD23(+) B cells in a cohort of Kenyan children undergoing repeated treatment and reinfection with Schistosoma mansoni.
Topics: Animals; Anthelmintics; Antibodies, Helminth; B-Lymphocytes; Child; Female; Humans; Immunoglobulin E | 2010 |
Use of fluorescent probes as a useful tool to identify resistant Schistosoma mansoni isolates to praziquantel.
Topics: Animals; Anthelmintics; Bisbenzimidazole; Digestive System; Drug Resistance; Fluorescent Dyes; Oxazi | 2010 |
Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice.
Topics: Administration, Oral; Androgen Antagonists; Animals; Anthelmintics; Disease Models, Animal; Female; | 2010 |
Schistosoma mansoni changes the activity of phase II drug-metabolizing enzymes: role of praziquantel as antibilharzial drug.
Topics: Animals; Disease Models, Animal; Glutathione; Glutathione Reductase; Glutathione Transferase; Liver; | 2010 |
ACTs for schistosomiasis: do they act?
Topics: Adolescent; Adult; Animals; Anthelmintics; Child; Child, Preschool; Herbal Medicine; Humans; Infant; | 2010 |
Praziquantel efficacy in mice infected with PZQ non-susceptible S. mansoni isolate treated with artemether: parasitological, biochemical and immunohistochemical assessment.
Topics: Alanine Transaminase; Animals; Anthelmintics; Artemether; Artemisinins; Aspartate Aminotransferases; | 2010 |
Detection of IgG1 and IgG4 subtypes reactive against potato apyrase in schistosomiasis patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anthelmintics; Antibodies, Helminth; Apyrase; C | 2010 |
Schistosomiasis control program in the state of Minas Gerais in Brazil.
Topics: Animals; Anthelmintics; Brazil; Feces; Health Education; Humans; National Health Programs; Praziquan | 2010 |
Spatial distribution of Schistosoma mansoni infection before and after chemotherapy with two praziquantel doses in a community of Pernambuco, Brazil.
Topics: Adolescent; Brazil; Child; Cluster Analysis; Feces; Female; Geographic Information Systems; Humans; | 2010 |
Factors related to transmission of and infection with Schistosoma mansoni in a village in the South-eastern Region of Brazil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albendazole; Animals; Biomphalaria; Brazil; Child; Child | 2010 |
Serological analysis of the outcome of treatment of Schistosoma mansoni infections with praziquantel.
Topics: Adolescent; Adult; Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Enzyme-Linked I | 2010 |
Immunological and parasitological parameters after treatment with dexamethasone in murine Schistosoma mansoni.
Topics: Adjuvants, Immunologic; Animals; Anthelmintics; Cytokines; Dexamethasone; Dioxoles; Drug Therapy, Co | 2010 |
Intestinal schistosomiasis in mothers and young children in Uganda: investigation of field-applicable markers of bowel morbidity.
Topics: Adolescent; Adult; Aged; Albendazole; Anthelmintics; Child; Child, Preschool; Feces; Female; Humans; | 2010 |
Comparative efficacy and bioavailability of different praziquantel brands.
Topics: Animals; Anthelmintics; Area Under Curve; Biological Availability; Cytochrome P-450 Enzyme System; C | 2011 |
Hepatosplenic schistosomiasis.
Topics: Adult; Anthelmintics; Hematemesis; Humans; Liver Diseases, Parasitic; Praziquantel; Schistosomiasis | 2010 |
Efficacy of two praziquantel treatments among primary school children in an area of high Schistosoma mansoni endemicity, Nile Delta, Egypt.
Topics: Animals; Anthelmintics; Child; Egypt; Endemic Diseases; Feces; Humans; Parasite Egg Count; Praziquan | 2011 |
Geographical distribution of intestinal schistosomiasis and soil-transmitted helminthiasis and preventive chemotherapy strategies in Sierra Leone.
Topics: Adolescent; Animals; Anthelmintics; Child; Child, Preschool; Feces; Female; Helminthiasis; Helminths | 2010 |
Observed reductions in Schistosoma mansoni transmission from large-scale administration of praziquantel in Uganda: a mathematical modelling study.
Topics: Adolescent; Adult; Animals; Anthelmintics; Child; Child, Preschool; Feces; Female; Humans; Infant; L | 2010 |
[Chronic hepatitis B with an unexpected coinfection].
Topics: Adult; Animals; Antiviral Agents; Biopsy; Comorbidity; Drug Administration Schedule; Drug Therapy, C | 2010 |
Similar cellular responses after treatment with either praziquantel or oxamniquine in Schistosoma mansoni infection.
Topics: Adolescent; Animals; Antigens, Helminth; Child; Cohort Studies; Cytokines; Enzyme-Linked Immunosorbe | 2009 |
Schistosoma mansoni infection: an immune complex disease presenting with polyarthritis.
Topics: Adult; Alanine Transaminase; Arthritis; Aspartate Aminotransferases; Biomarkers; Chronic Disease; Fe | 2013 |
Acute encephalitis caused by Schistosoma mansoni.
Topics: Adolescent; Animals; Anthelmintics; Antibodies, Helminth; Encephalitis; Feces; Fluorescent Antibody | 2010 |
Antischistosomal action of thioxo-imidazolidine compounds: an ultrastructural and cytotoxicity study.
Topics: Animals; Annexin A5; Apoptosis; Biomphalaria; Cell Survival; Enzyme Inhibitors; Female; Fluorescein- | 2011 |
Metabonomic investigation of human Schistosoma mansoni infection.
Topics: Adolescent; Adult; Aged; Animals; Anthelmintics; Biomarkers; Child; Cohort Studies; Feces; Female; H | 2011 |
Evaluation of immunological, parasitological and molecular methods for the diagnosis of Schistosoma mansoni infection before and after chemotherapy treatment with praziquantel in experimentally infected Nectomys squamipes.
Topics: Animals; Anthelmintics; Enzyme-Linked Immunosorbent Assay; Feces; Female; Male; Polymerase Chain Rea | 2011 |
Modulation of expression and activity of cytochrome P450s and alteration of praziquantel kinetics during murine schistosomiasis.
Topics: Animals; Anthelmintics; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Female | 2011 |
Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro.
Topics: Administration, Oral; Animals; Anthelmintics; Disease Models, Animal; Dose-Response Relationship, Dr | 2011 |
Praziquantel reverses pulmonary hypertension and vascular remodeling in murine schistosomiasis.
Topics: Animals; Anthelmintics; Blood Pressure; Blood Vessels; Cytokines; Down-Regulation; Female; Granuloma | 2011 |
High levels of Schistosoma mansoni infections among schoolchildren in central Sudan one year after treatment with praziquantel.
Topics: Adolescent; Animals; Anthelmintics; Child; Cohort Studies; Female; Humans; Longitudinal Studies; Mal | 2012 |
Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anthelmintics; Disease Models, Animal; Drug Therap | 2011 |
The use of pentoxifylline as adjuvant therapy with praziquantel downregulates profibrogenic cytokines, collagen deposition and oxidative stress in experimental schistosomiasis mansoni.
Topics: Animals; Collagen; Cytokines; Down-Regulation; Drug Therapy, Combination; Free Radical Scavengers; H | 2011 |
Schistosoma mansoni population structure and persistence after praziquantel treatment in two villages of Bahia, Brazil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anthelmintics; Brazil; Child; Child, Preschool; | 2011 |
Structural changes of Schistosoma mansoni adult worms recovered from C57BL/6 mice treated with radiation-attenuated vaccine and/or praziquantel against infection.
Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Therapy, Combination; Female; Immunotherapy; Ma | 2012 |
IL-10 blocks the development of resistance to re-infection with Schistosoma mansoni.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Eosinophils; Female; Immunoglobulin E; Immunoglobulin | 2011 |
Are obliterative pulmonary vascular lesions reversible?
Topics: Animals; Anthelmintics; Blood Vessels; Female; Hypertension, Pulmonary; Lung; Praziquantel; Schistos | 2011 |
Schistosoma mansoni encephalomyelitis.
Topics: Adult; Animals; Brain Neoplasms; Female; Humans; Praziquantel; Schistosoma mansoni; Schistosomiasis | 2011 |
Evidence of intra-hepatic vascular proliferation remodeling early after cure in experimental schistosomiasis mansoni: an immunohistochemical descriptive study.
Topics: Animals; Anthelmintics; Female; Immunohistochemistry; Liver; Liver Cirrhosis; Mice; Neovascularizati | 2012 |
Pharmacodynamics of mefloquine and praziquantel combination therapy in mice harbouring juvenile and adult Schistosoma mansoni.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female | 2011 |
MCR synthesis of praziquantel derivatives.
Topics: Animals; Anthelmintics; Chemistry Techniques, Synthetic; Cricetinae; Crystallography, X-Ray; Humans; | 2012 |
Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis.
Topics: Animals; Drug Therapy, Combination; Hydroxyproline; Liver; Liver Cirrhosis; Liver Function Tests; Ma | 2012 |
Mass drug administration significantly reduces infection of Schistosoma mansoni and hookworm in school children in the national control program in Sierra Leone.
Topics: Adolescent; Ancylostomatoidea; Animals; Anthelmintics; Child; Drug Therapy; Feces; Female; Hookworm | 2012 |
Tranilast ameliorates impaired hepatic functions in Schistosoma mansoni-infected mice.
Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Therapy, Combination; Liver Cirrhosis; Liver Di | 2012 |
Evaluation of avocado/soybean unsaponifiable alone or concurrently with praziquantel in murine schistosomiasis.
Topics: Administration, Oral; Animals; Anthelmintics; Cytokines; Disease Models, Animal; Drug Therapy, Combi | 2012 |
Susceptibility of a Brazilian wild rodent isolate of Schistosoma mansoni to praziquantel in mice.
Topics: Analysis of Variance; Animals; Anthelmintics; Brazil; Disease Reservoirs; Dose-Response Relationship | 2012 |
Antischistosomal activity of trioxaquines: in vivo efficacy and mechanism of action on Schistosoma mansoni.
Topics: Aminoquinolines; Animals; Anthelmintics; Drug Synergism; Female; Humans; Larva; Male; Mice; Praziqua | 2012 |
Therapeutic effect of alpha lipoic acid combined with praziquantel on liver fibrosis induced by Schistosoma mansoni challenged mice.
Topics: Animals; Anthelmintics; Antioxidants; Drug Therapy, Combination; Liver Cirrhosis; Male; Mice; Mice, | 2012 |
Bioavailability and in vivo efficacy of a praziquantel-polyvinylpyrrolidone solid dispersion in Schistosoma mansoni-infected mice.
Topics: Animals; Anthelmintics; Biological Availability; Drug Carriers; Male; Mice; Povidone; Praziquantel; | 2012 |
Schistosomiasis of the spinal cord: report of 5 cases from Sudan.
Topics: Adolescent; Adult; Animals; Anthelmintics; Child; Female; Humans; Lumbar Vertebrae; Male; Neuroschis | 2012 |
Myeloradiculopathy associated to Schistosoma mansoni.
Topics: Adolescent; Adrenal Cortex Hormones; Animals; Anthelmintics; Female; Humans; Magnetic Resonance Imag | 2011 |
Immunohistopathological changes in murine Schistosomiasis mansoni under the influence of N-acetyl-L-cysteine.
Topics: Acetylcysteine; Administration, Oral; Animals; Anthelmintics; Anti-Inflammatory Agents; Disease Mode | 2012 |
High level of Schistosoma mansoni infection in pre-school children in Sierra Leone highlights the need in targeting this age group for praziquantel treatment.
Topics: Animals; Anthelmintics; Child, Preschool; Cross-Sectional Studies; Feces; Female; Health Policy; Hum | 2012 |
Use of fecal occult blood tests as epidemiologic indicators of morbidity associated with intestinal schistosomiasis during preventive chemotherapy in young children.
Topics: Animals; Anthelmintics; Child, Preschool; Feces; Female; Humans; Infant; Male; Morbidity; Occult Blo | 2012 |
Efficacy and safety of two closely spaced doses of praziquantel against Schistosoma haematobium and S. mansoni and re-infection patterns in school-aged children in Niger.
Topics: Adolescent; Animals; Anthelmintics; Child; Cohort Studies; Drug-Related Side Effects and Adverse Rea | 2013 |
Cerebral vasculitis associated with Schistosoma mansoni infection.
Topics: Adult; Animals; Anthelmintics; Burkina Faso; Female; France; Humans; Praziquantel; Schistosoma manso | 2012 |
Praziquantel treatment of school children from single and mixed infection foci of intestinal and urogenital schistosomiasis along the Senegal River Basin: monitoring treatment success and re-infection patterns.
Topics: Adolescent; Animals; Anthelmintics; Child; Child, Preschool; Coinfection; Feces; Female; Humans; Mal | 2013 |
Effects of treatment on IgE responses against parasite allergen-like proteins and immunity to reinfection in childhood schistosome and hookworm coinfections.
Topics: Adolescent; Albendazole; Allergens; Ancylostomatoidea; Animals; Antibodies, Helminth; Antigens, Helm | 2013 |
Intestinal schistosomiasis in chimpanzees on Ngamba Island, Uganda: observations on liver fibrosis, schistosome genetic diversity and praziquantel treatment.
Topics: Animals; Anthelmintics; Ape Diseases; DNA Barcoding, Taxonomic; Feces; Female; Genetic Variation; Hu | 2013 |
Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium.
Topics: Administration, Oral; Animals; Anthelmintics; Chemoprevention; Child, Preschool; Cote d'Ivoire; Drug | 2012 |
Safety and efficacy of praziquantel syrup (Epiquantel®) against Schistosoma haematobium and Schistosoma mansoni in preschool-aged children in Niger.
Topics: Administration, Oral; Animals; Anthelmintics; Chemoprevention; Child, Preschool; Drug-Related Side E | 2013 |
Patterns of intestinal schistosomiasis among mothers and young children from Lake Albert, Uganda: water contact and social networks inferred from wearable global positioning system dataloggers.
Topics: Albendazole; Animals; Anthelmintics; Cercaria; Child; Child, Preschool; Environmental Exposure; Fema | 2012 |
Immunomodulatory effect of the alkaloidic extract of Solanum lycocarpum fruits in mice infected with Schistosoma mansoni.
Topics: Animals; Anthelmintics; Cell Count; Female; Fruit; Immunologic Factors; Interferon-gamma; Liver; Mac | 2013 |
The impact of single versus mixed Schistosoma haematobium and S. mansoni infections on morbidity profiles amongst school-children in Taveta, Kenya.
Topics: Adolescent; Albumins; Animals; Anthelmintics; Child; Child, Preschool; Coinfection; Cross-Sectional | 2013 |
Schistosoma mansoni myeloradiculopathy in an 8-year-old Omani boy.
Topics: Animals; Anthelmintics; Child; Humans; Magnetic Resonance Imaging; Male; Methylprednisolone; Neurosc | 2002 |
Parasitological and immunological changes in murine hepatic schistosomiasis before and after praziquantel treatment.
Topics: Animals; Anthelmintics; Feces; Hydroxyproline; Intestines; Liver; Liver Diseases, Parasitic; Mice; P | 2002 |
Resistance to praziquantel, effect of drug pressure and stability test.
Topics: Animals; Anthelmintics; Dose-Response Relationship, Drug; Drug Resistance; Humans; Lethal Dose 50; P | 2002 |
[Schistosomiasis of the spinal cord: analysis of 80 cases].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Brazil; Child; Child, Preschool; Dexamethasone; F | 2002 |
Drug resistance or tolerance in schistosomes?
Topics: Animals; Anthelmintics; Drug Resistance; Humans; Oxamniquine; Praziquantel; Schistosoma mansoni; Sch | 2002 |
Efficacy of oxamniquine and praziquantel in school children from two Schistosoma mansoni endemic areas.
Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Endemic Diseases; Humans; Log | 2002 |
The effect of treatment on the age-antibody relationship in children infected with Schistosoma mansoni and Schistosoma haematobium.
Topics: Adolescent; Age Factors; Analysis of Variance; Animals; Anthelmintics; Antibodies, Helminth; Antigen | 2002 |
Lack of C3 affects Th2 response development and the sequelae of chemotherapy in schistosomiasis.
Topics: Animals; Anthelmintics; Antigens, Helminth; Cells, Cultured; Complement C3; Cytokines; Immune Tolera | 2003 |
Adult worm tegumental damage and egg-granulomas in praziquantel-resistant and -susceptible Schistosoma mansoni treated in vivo.
Topics: Animals; Anthelmintics; Drug Resistance; Female; Granuloma; Liver Diseases, Parasitic; Male; Mice; M | 2002 |
IgG isotypes in schistosomiasis patients before and after praziquantel.
Topics: Animals; Anthelmintics; Enzyme-Linked Immunosorbent Assay; Feces; Female; Humans; Immunoglobulin G; | 2002 |
Human water contacts patterns in Schistosoma mansoni epidemic foci in northern Senegal change according to age, sex and place of residence, but are not related to intensity of infection.
Topics: Adolescent; Adult; Age Factors; Aged; Animals; Anthelmintics; Child; Disease Outbreaks; Environmenta | 2003 |
Some factors affecting prevalence of and immune responses to Schistosoma mansoni in schoolchildren in Gorgora, northwest Ethiopia.
Topics: Adolescent; Age Distribution; Anthelmintics; Antibodies, Helminth; Child; Cross-Sectional Studies; E | 2002 |
Schistosomiasis of the uterus in a patient with dysmenorrhoea and menorrhagia.
Topics: Adult; Dysmenorrhea; Female; Humans; Hysterectomy; Menorrhagia; Netherlands; Praziquantel; Schistoso | 2003 |
Effect of diazinon and/or praziquantel on selected protein aspects in healthy and Schistosoma mansoni infected mice.
Topics: Animals; Anthelmintics; Blood Proteins; Diazinon; Drug Interactions; Health; Insecticides; Lethal Do | 2003 |
Biochemical changes after subchronic and chronic interaction of Schistosoma mansoni infection in Swiss albino mice with two specific compounds.
Topics: Acetylcholinesterase; Alanine Transaminase; Animals; Brain; Diazinon; Drug Interactions; Liver; Male | 2003 |
High prevalence and morbidity of Schistosoma mansoni along the Albert Nile in Uganda.
Topics: Adolescent; Adult; Anthelmintics; Child; Child, Preschool; Cross-Sectional Studies; Feces; Humans; I | 2002 |
Treatment of acute schistosomiasis mansoni with praziquantel and an antifibrotic agent in mice. Maintenance of resistance to infection.
Topics: Acute Disease; Aminopropionitrile; Animals; Antiplatyhelmintic Agents; Drug Resistance; Fibrosis; Gr | 2003 |
[Acute encephalitis concurrent with primary infection by Schistosoma mansoni].
Topics: Adrenal Cortex Hormones; Adult; Animals; Anthelmintics; Antibodies, Helminth; Encephalitis; Humans; | 2003 |
Effect of simultaneous and/or consecutive administration of the broad spectrum anthelmintic flubendazole together with praziquantel in experimental Schistosoma mansoni infection.
Topics: Animals; Drug Therapy, Combination; Female; Granuloma; Liver; Male; Mebendazole; Mice; Parasite Egg | 2003 |
Acute schistosomiasis outbreak in the metropolitan area of Belo Horizonte, Minas Gerais: alert about the risk of unnoticed transmission increased by growing rural tourism.
Topics: Acute Disease; Animals; Biomphalaria; Brazil; Disease Outbreaks; Feces; Female; Health Knowledge, At | 2003 |
Evaluation of case management in the integrated schistosomiasis-control programme in Mali.
Topics: Case Management; Costs and Cost Analysis; Endemic Diseases; Hematuria; Humans; Mali; Praziquantel; P | 2003 |
Activity of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine against Schistosomiasis mansoni in mice.
Topics: Adenine; Animals; Female; Fertility; Granuloma; Intestines; Liver; Male; Mice; Organophosphonates; O | 2003 |
Altered immunoglobulin isotype profile and anti-immature worm surface immunoglobulins in mice harboring a praziquantel-resistant Schistosoma mansoni isolate.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Disease Models, Animal; Drug Resistance; Granuloma; Im | 2003 |
Efficacy and side effects of praziquantel against Schistosoma mansoni in a community of western Côte d'Ivoire.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anthelmintics; Child; Child, Presc | 2004 |
Measuring schistosomiasis case management of the health services in Ghana and Mali.
Topics: Adult; Analysis of Variance; Anthelmintics; Anti-Bacterial Agents; Case Management; Child; Delivery | 2004 |
Expression of matrix metalloproteinases and their inhibitors during the resorption of schistosome egg-induced fibrosis in praziquantel-treated mice.
Topics: Animals; Anthelmintics; Body Weight; Cell Count; Cells, Cultured; Collagen; Cytokines; Female; Gene | 2004 |
Changes in IgE- and antigen-dependent histamine-release in peripheral blood of Schistosoma mansoni-infected Ugandan fishermen after treatment with praziquantel.
Topics: Animals; Anthelmintics; Antibodies, Anti-Idiotypic; Antigens, Helminth; Cohort Studies; Enzyme-Linke | 2004 |
Antischistosomal effects of praziquantel, its alkaline hydrolysis and sun decomposed products on experimentally S. mansoni infected albino mice. (A) Efficacy assessment based on clinicopathological findings.
Topics: Administration, Oral; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Feces; Female; | 2004 |
Determination of ED50 values for praziquantel in praziquantel-resistant and -susceptible Schistosoma mansoni isolates.
Topics: Adolescent; Animals; Anthelmintics; Dose-Response Relationship, Drug; Drug Resistance; Female; Human | 2004 |
Validation of sensitivity to praziquantel using Schistosoma mansoni worm muscle tension and Ca2+-uptake as possible in vitro correlates to in vivo ED50 determination.
Topics: Animals; Anthelmintics; Calcium; Dose-Response Relationship, Drug; Drug Resistance; Lethal Dose 50; | 2004 |
Impairment of the Schistosoma mansoni-specific immune responses elicited by treatment with praziquantel in Ugandans with HIV-1 coinfection.
Topics: Adult; Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Cytokines; HIV Infections; | 2004 |
HTLV-1 modifies the clinical and immunological response to schistosomiasis.
Topics: Adult; Animals; Anthelmintics; Antigens, Helminth; Cells, Cultured; Female; HTLV-I Infections; Human | 2004 |
Lack of evidence for an antischistosomal activity of myrrh in experimental animals.
Topics: Animals; Anthelmintics; Cricetinae; Disease Models, Animal; Female; Humans; Male; Mesocricetus; Mice | 2004 |
Performance of IgG avidity in an area endemic for schistosomiasis in Egypt.
Topics: Acute Disease; Adolescent; Adult; Age Distribution; Aged; Animals; Antibodies, Protozoan; Antibody A | 2002 |
[A man from Surinam with haemorrhagic diarrhoea after long-standing schistosomiasis].
Topics: Adult; Animals; Anthelmintics; Chronic Disease; Colon, Sigmoid; Colonoscopy; Diarrhea; Feces; Gastro | 2004 |
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres | 2004 |
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres | 2004 |
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres | 2004 |
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres | 2004 |
Schistosoma mansoni of the conus medularis: case report.
Topics: Anthelmintics; Anti-Inflammatory Agents; Child; Dexamethasone; Female; Humans; Laminectomy; Lumbar V | 2004 |
Can somatostatin control acute bleeding from oesophageal varices in Schistosoma mansoni patients?[ISRCTN63456799].
Topics: Adolescent; Anthelmintics; Antihypertensive Agents; Child; Drug Therapy, Combination; Esophageal and | 2004 |
Regression of hepatosplenomegaly in Kenyan school-aged children after praziquantel treatment and three years of greatly reduced exposure to Schistosoma mansoni.
Topics: Adolescent; Age Distribution; Anthelmintics; Child; Cohort Studies; Female; Hepatomegaly; Humans; Ke | 2005 |
Rice irrigation and schistosomiasis in savannah and forest areas of Côte d'Ivoire.
Topics: Adolescent; Agriculture; Animals; Anthelmintics; Child; Child, Preschool; Cote d'Ivoire; Cross-Secti | 2005 |
Evaluation of oral therapy on Mansonial Schistosomiasis using single dose of Balanites aegyptiaca fruits and praziquantel.
Topics: Administration, Oral; Animals; Anthelmintics; Balanites; Drug Therapy, Combination; Feces; Female; F | 2005 |
Praziquantel for the treatment of schistosomiasis mansoni during pregnancy.
Topics: Administration, Oral; Adult; Anthelmintics; Female; Humans; Praziquantel; Pregnancy; Pregnancy Compl | 2005 |
Schistosoma mansoni in family 5 years after safari.
Topics: Adult; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Blotting, Western; Child; Enzyme-Linked | 2005 |
[Malaise and abdominal complaints in a 24-year-old Swiss-African patient from Guinea: schistosomiasis mansoni].
Topics: Abdominal Pain; Adult; Anthelmintics; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Pr | 2005 |
Treatment of Schistosoma mansoni infection increases helminth-specific type 2 cytokine responses and HIV-1 loads in coinfected Ugandan adults.
Topics: Adult; Anthelmintics; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Female; HIV Infections; Huma | 2005 |
[Surprising findings in the colon 15 years after a holiday in Africa].
Topics: Abdominal Pain; Aged; Animals; Anthelmintics; Antibodies, Helminth; Colon; Colonoscopy; Female; Germ | 2005 |
Artemether as adjuvant therapy to praziquantel in murine Egyptian schistosomiasis mansoni.
Topics: Administration, Oral; Animals; Artemether; Artemisinins; Drug Therapy, Combination; Female; Liver; M | 2005 |
Early post-treatment immunoglobulin profile in human schistosomiasis.
Topics: Adolescent; Adult; Animals; Anthelmintics; Antibodies, Helminth; Antibody Specificity; Antigens, Hel | 2005 |
Current status of sensitivity to praziquantel in a focus of potential drug resistance in Egypt.
Topics: Adult; Animals; Anthelmintics; Drug Resistance; Egypt; Female; Humans; Liver Diseases, Parasitic; Ma | 2005 |
Schistosoma mansoni infection and liver graft.
Topics: Adult; Anthelmintics; Humans; Liver Transplantation; Male; Middle Aged; Postoperative Complications; | 2005 |
Paucisymptomatic brainstem lesions revealing CNS schistosomiasis.
Topics: Aged; Animals; Anthelmintics; Cerebrovascular Circulation; Dizziness; Encephalitis; Female; Headache | 2005 |
Combined Schistosoma mansoni and Schistosoma haematobium infection.
Topics: Adolescent; Anthelmintics; Feces; Female; Humans; Parasite Egg Count; Praziquantel; Schistosomiasis | 2005 |
Therapeutic effect of subcurative dose praziquantel on Schistosoma mansoni infected mice and resistance to challenge infection after treatment.
Topics: Animals; Animals, Outbred Strains; Anthelmintics; Antibodies, Helminth; Drug Administration Schedule | 2005 |
Hepatic and intestinal schistosomiasis after orthotopic liver transplant.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Biopsy; Diagnosis, Differential; Follow-Up Studies; Hu | 2005 |
Applied and basic research on the epidemiology, morbidity, and immunology of schistosomiasis in fishing communities on Lake Albert, Uganda.
Topics: Animals; Anthelmintics; Cohort Studies; Drug Resistance; Female; Fisheries; Fresh Water; Humans; Liv | 2006 |
Progress towards countrywide control of schistosomiasis and soil-transmitted helminthiasis in Uganda.
Topics: Adolescent; Albendazole; Anthelmintics; Child; Child, Preschool; Health Care Costs; Helminthiasis; H | 2006 |
The efficacy of human schistosomicide treatment may depend on the rate of transmission.
Topics: Animals; Antibodies, Helminth; Fluorescent Antibody Technique, Indirect; Humans; Immunoglobulin M; O | 2006 |
A case of bowel schistosomiasis not adhering to endoscopic findings.
Topics: Adult; Animals; Anthelmintics; Feces; Humans; Intestinal Mucosa; Male; Parasite Egg Count; Praziquan | 2005 |
Bayesian spatial analysis and disease mapping: tools to enhance planning and implementation of a schistosomiasis control programme in Tanzania.
Topics: Adolescent; Adult; Anthelmintics; Bayes Theorem; Child; Communicable Disease Control; Female; Health | 2006 |
Parasitological, hematological and ultrastructural study of the effect of COX-2 inhibitor, pyocyanin pigment and praziquantel, on S. mansoni infected mice.
Topics: Animals; Anthelmintics; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Leukocyte Count; Mal | 2006 |
Lumbar intramedullary spinal schistosomiasis presenting as progressive paraparesis: case report.
Topics: Adult; Animals; Diagnosis, Differential; Humans; Lumbosacral Region; Male; Neuroschistosomiasis; Par | 2006 |
Eosinophil activity in Schistosoma mansoni infections in vivo and in vitro in relation to plasma cytokine profile pre- and posttreatment with praziquantel.
Topics: Adolescent; Adult; Animals; Antigens, Helminth; Cells, Cultured; Cytokines; Eosinophil Cationic Prot | 2006 |
Effect of artemether administered alone or in combination with praziquantel to mice infected with Plasmodium berghei or Schistosoma mansoni or both.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Drug Therapy, Combination; Female; Humans; Intesti | 2006 |
Prolonged latent schistosomiasis diagnosed 38 years after infestation in a HIV patient.
Topics: Adult; Animals; Anthelmintics; Biopsy, Needle; France; HIV Seropositivity; Humans; Liver; Male; Praz | 2006 |
Morbidity indicators of Schistosoma mansoni: relationship between infection and anemia in Ugandan schoolchildren before and after praziquantel and albendazole chemotherapy.
Topics: Adolescent; Albendazole; Anemia; Animals; Anthelmintics; Child; Feces; Female; Hemoglobins; Humans; | 2006 |
Triclabendazole and its two main metabolites lack activity against Schistosoma mansoni in the mouse model.
Topics: Animals; Anthelmintics; Benzimidazoles; Disease Models, Animal; Feces; Female; Liver; Male; Mesenter | 2006 |
A combined school- and community-based campaign targeting all school-age children of Burkina Faso against schistosomiasis and soil-transmitted helminthiasis: performance, financial costs and implications for sustainability.
Topics: Adolescent; Albendazole; Animals; Anthelmintics; Burkina Faso; Child; Child, Preschool; Drug Costs; | 2006 |
Factors affecting human IgE and IgG responses to allergen-like Schistosoma mansoni antigens: Molecular structure and patterns of in vivo exposure.
Topics: Adolescent; Adult; Allergens; Amino Acid Sequence; Animals; Anthelmintics; Antibodies, Helminth; Ant | 2007 |
Mazzotti-like reaction after treatment with praziquantel for schistosomiasis.
Topics: Abdominal Pain; Adolescent; Animals; Anthelmintics; Exanthema; Fever; Humans; Male; Praziquantel; Re | 2006 |
Cerebral schistosomiasis.
Topics: Adult; Anthelmintics; Brain Diseases; Carbamazepine; Humans; Magnetic Resonance Imaging; Male; Neuro | 2006 |
Impact of National Schistosomiasis Control Program in Kafr El-Sheikh governorate, Nile Delta, Egypt: an independent evaluation.
Topics: Adult; Age Distribution; Anthelmintics; Chi-Square Distribution; Egypt; Endemic Diseases; Humans; Lo | 1998 |
Drug-metabolizing enzymes and praziquantel bioavailability in mice harboring Schistosoma mansoni isolates of different drug susceptibilities.
Topics: Animals; Anthelmintics; Biological Availability; Cytochrome P-450 Enzyme System; Cytochromes b5; Hum | 2006 |
The spatial distribution of Schistosoma mansoni infection before and after chemotherapy in the Jequitinhonha Valley in Brazil.
Topics: Adolescent; Adult; Albendazole; Animals; Anthelmintics; Brazil; Child; Child, Preschool; Feces; Fema | 2006 |
Remodeling of hepatic vascular changes after specific chemotherapy of schistosomal periportal fibrosis.
Topics: Animals; Anthelmintics; Chronic Disease; Disease Models, Animal; Female; Granuloma; Humans; Liver Ci | 2006 |
Associations between specific antibody responses and resistance to reinfection in a Senegalese population recently exposed to Schistosoma mansoni.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Anthelmintics; Antibodies, Helminth; C | 2007 |
Field-based evaluation of a reagent strip test for diagnosis of Schistosoma mansoni by detecting circulating cathodic antigen in urine before and after chemotherapy.
Topics: Adolescent; Adult; Aged; Anthelmintics; Antigens, Helminth; Child; Cross-Sectional Studies; Ethiopia | 2007 |
[Portopulmonary hypertension due to schistosomiasis in two Malagasy patients].
Topics: Adolescent; Adult; Anthelmintics; Ascites; Combined Modality Therapy; Diet, Sodium-Restricted; Dyspn | 2007 |
Studies on parasitologic and haematologic activities of an enaminone derivative of 4-hydroxyquinolin-2(1H)-one against murine schistosomiasis mansoni.
Topics: Animals; Female; Hydroxyquinolines; Male; Mice; Parasite Egg Count; Praziquantel; Schistosoma manson | 2007 |
Evaluation of the effect of oxamniquine, praziquantel and a combination of both drugs on the intramolluscan phase of Schistosoma mansoni.
Topics: Animals; Anthelmintics; Biomphalaria; Drug Therapy, Combination; Oxamniquine; Praziquantel; Schistos | 2007 |
Mansoni's schistosomiasis of a leiomyoma: case report.
Topics: Adult; Animals; Anthelmintics; Female; Humans; Leiomyoma; Praziquantel; Schistosomiasis mansoni; Ute | 2007 |
Immunohistopathological and biochemical changes in Schistosoma mansoni-infected mice treated with artemether.
Topics: Animals; Apoptosis; Artemether; Artemisinins; Granuloma; Histocytochemistry; Liver; Liver Function T | 2007 |
Antischistosomal and liver protective effects of Curcuma longa extract in Schistosoma mansoni infected mice.
Topics: Animals; Curcuma; Humans; Liver; Male; Mice; Parasite Egg Count; Phytotherapy; Plant Extracts; Prazi | 2007 |
Effect of Curcuma longa or parziquantel on Schistosoma mansoni infected mice liver--histological and histochemical study.
Topics: Alkaline Phosphatase; Animals; Body Weight; Curcuma; Liver Diseases; Male; Mice; Organ Size; Phytoth | 2007 |
T regulatory cell levels decrease in people infected with Schistosoma mansoni on effective treatment.
Topics: Adolescent; Adult; Animals; Anthelmintics; CD4-Positive T-Lymphocytes; Eosinophilia; HIV Seropositiv | 2007 |
Hepatosplenomegaly in Kenyan schoolchildren: exacerbation by concurrent chronic exposure to malaria and Schistosoma mansoni infection.
Topics: Adolescent; Animals; Anthelmintics; Child; Child, Preschool; Cross-Sectional Studies; Female; Hepato | 2007 |
Assessment of Schistosoma mansoni induced intestinal inflammation by means of eosinophil cationic protein, eosinophil protein X and myeloperoxidase before and after treatment with praziquantel.
Topics: Adolescent; Adult; Animals; Anthelmintics; Biomarkers; Child; Cohort Studies; Enzyme-Linked Immunoso | 2008 |
Modulation of the antioxidant defence in different developmental stages of Schistosoma mansoni by praziquantel and artemether.
Topics: Analysis of Variance; Animals; Antioxidants; Artemether; Artemisinins; Humans; Oxidative Stress; Pra | 2007 |
Reversibility of schistosomal periportal thickening/fibrosis after praziquantel therapy: a twenty-six month follow-up study in Ethiopia.
Topics: Adolescent; Adult; Aged; Animals; Anthelmintics; Antibodies, Viral; Child; Ethiopia; Feces; Female; | 2008 |
Immune response of mice infected with Schistosoma mansoni is modulated by antifibrotic treatment.
Topics: Aminopropionitrile; Animals; Antiplatyhelmintic Agents; Drug Therapy, Combination; Female; Granuloma | 1995 |
Transverse myelitis in a child with Down's syndrome and schistosomal colitis.
Topics: Child; Colitis; Down Syndrome; Humans; Male; Myelitis, Transverse; Praziquantel; Schistosomiasis man | 1993 |
Schistosoma mansoni: molecular cloning and sequencing of the 200-kDa chemotherapeutic target antigen.
Topics: Amino Acid Sequence; Animals; Antibodies, Helminth; Antigens, Helminth; Base Sequence; Blotting, Nor | 1995 |
Effect of chemotherapy on immune response to egg antigens of Schistosoma mansoni in chronically infected children from areas of low transmission.
Topics: Adolescent; Animals; Antibodies, Helminth; Antigens, Helminth; Blotting, Western; Child; Child, Pres | 1995 |
Enhanced efficacy of praziquantel treatment in mice vaccinated with radiation attenuated cercariae of Schistosoma mansoni.
Topics: Animals; Female; Gamma Rays; Immunoglobulin E; Male; Mice; Praziquantel; Schistosoma mansoni; Schist | 1995 |
Schistosomal glomerulopathy: a putative role for commonly associated Salmonella infection.
Topics: Animals; Antibodies, Helminth; Chloramphenicol; Complement C3; Fibrosis; Glomerulonephritis; Humans; | 1995 |
Effect of praziquantel treatment on hepatic pathology of Schistosoma mansoni experimentally infected mice.
Topics: Animals; Liver; Mice; Praziquantel; Schistosomiasis mansoni | 1995 |
Efficacy of treatment of murine Schistosoma mansoni infections with praziquantel and oxamniquine correlates with infection intensity: role of host antibody.
Topics: Animals; Antibodies, Helminth; Antigens, Protozoan; Female; Male; Mice; Oxamniquine; Praziquantel; S | 1995 |
Fistula-in-ano: an unusual presentation of chronic schistosomiasis.
Topics: Adult; Animals; Chronic Disease; Feces; Humans; Male; Praziquantel; Rectal Fistula; Schistosoma mans | 1995 |
Short report: diminished susceptibility to praziquantel in a Senegal isolate of Schistosoma mansoni.
Topics: Animals; Biomphalaria; Drug Resistance; Kenya; Mice; Mice, Inbred CBA; Praziquantel; Puerto Rico; Sc | 1995 |
Immune complexes as monitors of cure in Schistosoma mansoni infected mice.
Topics: Animals; Antigen-Antibody Complex; Biomarkers; Enzyme-Linked Immunosorbent Assay; Mice; Praziquantel | 1995 |
Detection of circulating schistosome antigens in serum and urine of schistosomiasis patients and assessment of cure by a monoclonal antibody.
Topics: Adolescent; Adult; Animals; Antibodies, Monoclonal; Antigens, Helminth; Biomarkers; Child; Enzyme-Li | 1995 |
Active immunization of mice with Schistosoma mansoni worm membrane antigens enhances efficacy of praziquantel.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Antigens, Surface; Blotting, Western; Cell Membra | 1995 |
[Acute schistosomiasis (Katayama fever)].
Topics: Acute Disease; Child; Feces; Female; Humans; Praziquantel; Schistosomiasis mansoni; Travel | 1995 |
Efficacy and side effects of praziquantel in an epidemic focus of Schistosoma mansoni.
Topics: Adolescent; Adult; Aged; Animals; Antigens, Helminth; Child; Child, Preschool; Cohort Studies; Disea | 1995 |
A statistical approach to schistosome population dynamics and estimation of the life-span of Schistosoma mansoni in man.
Topics: Adolescent; Adult; Age Factors; Animals; Child; Child, Preschool; Feces; Host-Parasite Interactions; | 1995 |
Epidemic schistosomiasis in the delta of the Senegal River Basin, Senegal: responses of the health care system.
Topics: Adolescent; Animals; Biomphalaria; Bulinus; Child; Child, Preschool; Health Education; Humans; Pest | 1994 |
Schistosoma mansoni infection involving the spinal cord. Case report.
Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Myelitis, Transverse; Praziquantel; Schistosomiasis | 1995 |
[Schistosomiasis mansoni infection in a hyperendemic region of midwestern Madagascar: epidemiology, morbidity and secondary effects of praziquantel treatment].
Topics: Adolescent; Adult; Age Distribution; Child; Child, Preschool; Female; Humans; Infant; Infant, Newbor | 1994 |
Efficacy of a combination of metrifonate and praziquantel in the treatment of Schistosoma mansoni infection in albino mice.
Topics: Animals; Drug Combinations; Drug Interactions; Mice; Praziquantel; Schistosomiasis mansoni; Trichlor | 1995 |
Observations on the effects of different chemotherapy strategies on the transmission of Schistosoma mansoni in Machakos District, Kenya, measured by long-term snail sampling and cercariometry.
Topics: Animals; Biomphalaria; Child; Disease Vectors; Ecosystem; Humans; Kenya; Praziquantel; Rain; Schisto | 1994 |
Treatment of schistosomiasis with praziquantel among school children.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Egypt; Humans; Infant; Praziquantel; Preval | 1994 |
Effect of praziquantel on sex hormone levels in murine schistosomiasis mansoni.
Topics: Animals; Estradiol; Female; Male; Mice; Ovary; Praziquantel; Progesterone; Schistosomiasis mansoni; | 1994 |
Laboratory induced resistance to praziquantel in experimental schistosomiasis.
Topics: Animals; Dose-Response Relationship, Drug; Drug Resistance; Mice; Praziquantel; Schistosoma mansoni; | 1994 |
Quantification of praziquantel-induced damage on the surface of adult Schistosoma mansoni worms: estimation of esterase and alkaline phosphatase activity.
Topics: Alkaline Phosphatase; Animals; Antigens, Helminth; Esterases; Mice; Praziquantel; Schistosoma manson | 1994 |
Epidemiological studies on Schistosoma mansoni infection in the western region of Saudi Arabia using the potassium hydroxide stool digestion technique.
Topics: Adolescent; Adult; Age Distribution; Child; Child, Preschool; Feces; Female; Humans; Hydroxides; Inf | 1995 |
Praziquantel-induced exposure of Schistosoma mansoni alkaline phosphatase: drug-antibody synergy which acts preferentially against female worms.
Topics: Alkaline Phosphatase; Animals; Antibodies, Helminth; Antibody Specificity; Drug Synergism; Female; F | 1994 |
Control of Schistosoma mansoni and intestinal helminths: 8-year follow-up of an urban school programme in Bujumbura, Burundi.
Topics: Adolescent; Burundi; Child; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Male; Parasi | 1994 |
Treatment of experimental schistosomiasis mansoni with praziquantel alone and combined with cimetidine.
Topics: Animals; Cimetidine; Drug Synergism; Drug Therapy, Combination; Mice; Praziquantel; Schistosomiasis | 1994 |
[Intestinal bilharziasis with rectal bleeding: apropos of 3 cases].
Topics: Adult; Diarrhea; Female; Gastrointestinal Hemorrhage; Humans; Praziquantel; Rectum; Schistosomiasis | 1994 |
Reduction in tissue egg load and maintenance of resistance to challenge in mice infected with Schistosoma mansoni, following combined treatment with praziquantel and an antifibrotic agent.
Topics: Aminopropionitrile; Animals; Drug Therapy, Combination; Feces; Female; Granuloma; Intestines; Liver; | 1994 |
Impact of repeated community-based selective chemotherapy on morbidity due to schistosomiasis mansoni.
Topics: Abdominal Pain; Adolescent; Adult; Age Factors; Burundi; Child; Child, Preschool; Cluster Analysis; | 1994 |
Schistosomiasis prevalence after administration of praziquantel to school children in Melela village, Morogoro region, Tanzania.
Topics: Adolescent; Child; Feces; Female; Follow-Up Studies; Hematuria; Humans; Incidence; Male; Morbidity; | 1993 |
Alkaline phosphatase as marker of Schistosoma mansoni egg viability.
Topics: Alkaline Phosphatase; Animals; Intestines; Liver; Male; Mice; Ovum; Praziquantel; Schistosoma manson | 1994 |
Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific.
Topics: Animals; Drug Resistance; Female; Male; Mice; Oxamniquine; Praziquantel; Schistosoma mansoni; Schist | 1994 |
Gene expression of transforming growth factor beta 1 and extracellular matrix proteins in murine Schistosoma mansoni infection.
Topics: Animals; Extracellular Matrix Proteins; Female; Fibrosis; Gene Expression; Liver; Mice; Mice, Inbred | 1994 |
The physical fitness and work performance of agricultural workers infected with Schistosoma mansoni in Zimbabwe.
Topics: Adult; Age Factors; Agricultural Workers' Diseases; Feces; Humans; Male; Middle Aged; Physical Fitne | 1993 |
Effect of praziquantel treatment on lipid peroxide levels and superoxide dismutase activity in tissues of healthy and Schistosoma mansoni infected mice.
Topics: Animals; Kidney; Lipid Peroxides; Liver; Male; Malondialdehyde; Mice; Praziquantel; Schistosoma mans | 1994 |
Histopathological evidences for the antifibrogenic effect of colchicine in schistosomiasis mansoni in mice.
Topics: Animals; Colchicine; Drug Therapy, Combination; Granuloma; Liver; Liver Cirrhosis; Mice; Praziquante | 1994 |
Assessment of praziquantel therapy in treatment of Schistosoma mansoni infection.
Topics: Drug Resistance; Egypt; Feces; Female; Humans; Male; Parasite Egg Count; Praziquantel; Prevalence; S | 1994 |
Schistosoma mansoni eggs as a target for praziquantel: efficacy of oral application in mice.
Topics: Administration, Oral; Animals; Drug Administration Schedule; Drug Evaluation, Preclinical; Feces; In | 1994 |
Effect of praziquantel on platelet levels in mice infected with S. mansoni.
Topics: Animals; Drug Evaluation, Preclinical; Female; Male; Mice; Mice, Inbred BALB C; Platelet Count; Praz | 1993 |
Schistosoma mansoni: immunoreactivity of human sera with the surface antigen Sm23.
Topics: Age Factors; Animals; Antibodies, Helminth; Antigens, Helminth; Antigens, Surface; Base Sequence; Bl | 1993 |
Clinical and immunological study of schistosomal myeloradiculopathy.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Immunoglobulin G; Male; Middle Age | 1993 |
The effect of praziquantel treatment on the liver functions, worm burden, and granuloma size using two drug regimen in murine Schistosoma mansoni infection.
Topics: Animals; Female; Granuloma; Liver; Male; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis ma | 1993 |
Enhancement of eosinophil-mediated cytotoxicity to schistosomula of Schistosoma mansoni by autologous mononuclear cells from patients.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Cells, Cultured; Complement System Proteins; Cyto | 1993 |
Regression of hepatic lesions after treatment of Schistosoma mansoni or Schistosoma japonicum infection in mice: a comparative study.
Topics: Animals; Collagen; Granuloma; Hydroxyproline; Liver; Lung; Mice; Praziquantel; Schistosoma japonicum | 1993 |
Experimental schistomiasis: the effect of chemotherapy on concomitant immunity and resistance to reinfection.
Topics: Animals; Immunity, Active; Mice; Praziquantel; Recurrence; Schistosomiasis mansoni; Time Factors | 1993 |
An experimental study on the effect of praziquantel and oltipraz on some lysosomal enzymes.
Topics: Animals; Follow-Up Studies; Glucuronidase; Liver; Lysosomes; Male; Mice; Naphthol AS D Esterase; Pra | 1993 |
Assessment of serum copper and zinc levels in chronic Schistosoma mansoni patients with and without hepatic involvement before and after praziquantel therapy.
Topics: Adult; Copper; Female; Humans; Male; Praziquantel; Schistosomiasis mansoni; Zinc | 1993 |
Schistosomiasis mansoni in Burundi: progress in its control since 1985.
Topics: Adolescent; Adult; Animals; Anthelmintics; Burundi; Child; Humans; Levamisole; Mebendazole; Niclosam | 1993 |
Variations of direct fluorescent antibody test and serum bile acids levels following praziquantel treatment in Schistosoma mansoni experimentally infected mice.
Topics: Animals; Bile Acids and Salts; Female; Fluorescent Antibody Technique, Direct; Male; Mice; Praziquan | 1995 |
Temporal differences in praziquantel- and oxamniquine-induced tegumental damage to adult Schistosoma mansoni: implications for drug-antibody synergy.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Blotting, Western; Drug Synergism; Enzyme-Linked | 1996 |
Effect of schistosomal infection and its treatment on some key enzymes of glucose metabolism in mice livers.
Topics: Animals; Body Weight; Citric Acid Cycle; Female; Glucose; Glycolysis; Liver; Liver Glycogen; Male; M | 1995 |
Case 4-1996: paralysis due to schistosomiasis.
Topics: Drug Resistance; Humans; Oxamniquine; Praziquantel; Schistosomiasis mansoni; Schistosomicides | 1996 |
Case 4-1996: paralysis due to schistosomiasis.
Topics: Humans; Oxamniquine; Praziquantel; Schistosomiasis mansoni; Schistosomicides; Spinal Cord Diseases | 1996 |
[Schistosomiasis at Marselisborg hospital 1981-1990].
Topics: Africa; Antiplatyhelmintic Agents; Denmark; Emigration and Immigration; Humans; Praziquantel; Retros | 1996 |
Impact of population-based selective chemotherapy on prevalence and intensity of Schistosoma mansoni infections in the Nile Delta: Kafr El Sheikh.
Topics: Adolescent; Adult; Aged; Antiplatyhelmintic Agents; Child; Child, Preschool; Cross-Sectional Studies | 1995 |
Ultrasonography in a Senegalese community recently exposed to Schistosoma mansoni infection.
Topics: Adolescent; Adult; Aged; Antiplatyhelmintic Agents; Child; Child, Preschool; Cohort Studies; Female; | 1996 |
Synthesis and antischistosomal activity of a new 2-nicotinoyl dipeptide analogue of praziquantel.
Topics: Animals; Female; Liver; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosom | 1996 |
Effect of some parasitic infection on neurotransmitters in the brain of experimentally infected mice before and after treatment.
Topics: Animals; Brain; Dopamine; Mebendazole; Mice; Neurotransmitter Agents; Norepinephrine; Parasitic Dise | 1996 |
Effect of anti-schistosomal treatment on schistosomal hepatic pathology: an experimental study in Syrian golden hamsters.
Topics: Animals; Antiplatyhelmintic Agents; Biomphalaria; Blood Proteins; Cricetinae; Granuloma; Liver; Meso | 1996 |
Characterization of isolates of Schistosoma mansoni from Egyptian villagers that tolerate high doses of praziquantel.
Topics: Adult; Animals; Antiplatyhelmintic Agents; Biological Availability; Confounding Factors, Epidemiolog | 1996 |
Effect of adamantylamide dipeptide on reinfection resistance after primary infection eradication in experimental Schistosomiasis mansoni.
Topics: Adjuvants, Immunologic; Amantadine; Animals; Antibody Formation; Antiplatyhelmintic Agents; Dipeptid | 1996 |
Host and parasite determinants of morbidity in Egyptian children with schistosomiasis.
Topics: Animals; Antibodies, Helminth; Antiplatyhelmintic Agents; Child; Egypt; Eosinophils; Host-Parasite I | 1996 |
[Mansonic neuroschistosomiasis: clinical, laboratory and therapeutic aspects].
Topics: Adolescent; Adult; Female; Humans; Male; Meningitis; Middle Aged; Myelitis; Praziquantel; Prednisone | 1996 |
Effect of two trematodicidal drugs on the morphology and tegumentary ultrastructure of Schistosoma mansoni.
Topics: Animals; Antiplatyhelmintic Agents; Benzimidazoles; Mice; Microscopy, Electron, Scanning; Praziquant | 1997 |
Clinical, parasitological and immunological features of canal cleaners hyper-exposed to Schistosoma mansoni in the Sudan.
Topics: Adult; Antibodies, Helminth; Antigens, Helminth; Antiplatyhelmintic Agents; Enzyme-Linked Immunosorb | 1996 |
Schistosoma mansoni: maturation rate and drug susceptibility of different geographic isolates.
Topics: Animals; Digestive System; Drug Resistance; Feces; Female; Fertility; Kenya; Liver; Male; Mice; Oxam | 1997 |
Efficacy of an antipathology vaccine in murine schistosomiasis administered with and without chemotherapy.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Female; Granuloma; Immune Tolerance; Immunoglobul | 1996 |
Schistosomiasis in the Senegal River Basin: before and after the construction of the dams at Diama, Senegal and Manantali, Mali and future prospects.
Topics: Animals; Antiplatyhelmintic Agents; Environment; Forecasting; Humans; Mali; Praziquantel; Prevalence | 1997 |
Urinary excretion of the collagen cross-link pyridinoline increases during liver fibrogenesis.
Topics: Amino Acids; Animals; Antiplatyhelmintic Agents; Chromatography, High Pressure Liquid; Chronic Disea | 1997 |
Schistosomiasis: an unusual cause of right lower quadrant abdominal pain.
Topics: Abdominal Pain; Appendicitis; Appendix; Cecal Diseases; Diagnosis, Differential; Emigration and Immi | 1997 |
Comparative effect of tiaprofenic acid and piroxicam alone and as adjuvants to praziquantel in Schistosoma mansoni infected mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclic AMP; Dinoprostone; Drug Therapy, Combinatio | 1997 |
Effect of praziquantel and oxamniquine treatment on human isotype responses to Schistosoma mansoni: elevated IgE to adult worm.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Drug Therapy, Combination; Female; Humans; Immuno | 1997 |
The impact of passive chemotherapy on Schistosoma mansoni prevalence and intensity of infection in the Egyptian Nile Delta.
Topics: Adolescent; Adult; Child; Child, Preschool; Egypt; Feces; Female; Humans; Infant; Male; Middle Aged; | 1997 |
Membrane internalization processes in different stages of Schistosoma mansoni as shown by a styryl dye (Frei Mao 1-43).
Topics: Animals; Calcium; Endocytosis; Fluorescent Dyes; Genistein; Life Cycle Stages; Membranes; Mice; Orga | 1998 |
Seasonality as a determinant of the efficacy of praziquantel in population-based chemotherapy: lessons from the practice.
Topics: Animals; Egypt; Female; Humans; Male; Population Surveillance; Praziquantel; Schistosomiasis haemato | 1998 |
Octreotide decreases connective tissue formation and improves vascular changes associated with hepatic schistosomiasis.
Topics: Animals; Drug Therapy, Combination; Egypt; Female; Liver Cirrhosis; Liver Diseases, Parasitic; Mice; | 1998 |
An investigation into the interaction between drug efficacy and drug price of praziquantel in determining the cost-effectiveness of school-targeted treatment for Schistosoma mansoni using a population dynamic model.
Topics: Adolescent; Animals; Antiplatyhelmintic Agents; Child; Cost-Benefit Analysis; Female; Global Health; | 1998 |
Phenotypic analysis of cellular immune response in Swiss albino mice immunized with antigen extract from exposed B. alexandrina subjected to UV-, gamma irradiation and praziquantel treatment.
Topics: Animals; Antigens, Helminth; Biomphalaria; Gamma Rays; Immunization; Immunophenotyping; Lymphocyte S | 1998 |
Studies on schistosomiasis in western Kenya: II. Efficacy of praziquantel for treatment of schistosomiasis in persons coinfected with human immunodeficiency virus-1.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Antiplatyhelmintic Agents; CD4 Lymphocyte Count; | 1998 |
Effect of octreotide on the pathology of hepatic schistosomiasis.
Topics: Animals; Blood Vessels; Collagen; Drug Synergism; Female; Liver; Liver Cirrhosis, Experimental; Live | 1998 |
Schistosoma mansoni infection in owl monkeys (Aontus nancymai): evidence for the early elimination of adult worms.
Topics: Animals; Aotidae; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Feces; Granuloma; Hemat | 1998 |
Schistosomal myelopathy: relevance and limits of contrast-enhanced magnetic resonance imaging in spinal cord infections.
Topics: Adult; Combined Modality Therapy; Contrast Media; Humans; Image Enhancement; Magnetic Resonance Imag | 1998 |
Protein deficiency impairs the schistosomicidal action of praziquantel.
Topics: Animals; Drug Synergism; Female; Mice; Mice, Inbred C57BL; Praziquantel; Protein Deficiency; Schisto | 1998 |
Praziquantel side effects and efficacy related to Schistosoma mansoni egg loads and morbidity in primary school children in north-east Ethiopia.
Topics: Animals; Child; Cohort Studies; Ethiopia; Feces; Humans; Parasite Egg Count; Praziquantel; Schistoso | 1999 |
Meckel's diverticulitis associated with Schistosoma mansoni.
Topics: Adolescent; Animals; Child; Child, Preschool; Eosinophilia; Female; Humans; Male; Meckel Diverticulu | 1999 |
Adult resistance to schistosomiasis mansoni: age-dependence of reinfection remains constant in communities with diverse exposure patterns.
Topics: Adolescent; Adult; Age Factors; Animals; Antiplatyhelmintic Agents; Child; Child, Preschool; Female; | 1999 |
Seroepidemiology of schistosomiasis in Puerto Rico: evidence for vanishing endemicity.
Topics: Adult; Animals; Antibodies, Helminth; Antigens, Helminth; Endemic Diseases; Female; Humans; Male; Pr | 1999 |
Relationships between several markers of extracellular matrix turn-over and ultrasonography in human Schistosomiasis mansoni.
Topics: Amino Acids; Biomarkers; Collagen; E-Selectin; Extracellular Matrix; Humans; Hyaluronic Acid; Interc | 1999 |
Control of schistosomiasis pathology by combination of Sm28GST DNA immunization and praziquantel treatment.
Topics: Animals; Antibodies, Helminth; Combined Modality Therapy; DNA, Helminth; Glutathione Transferase; Mi | 1999 |
Evidence for a long-term effect of a single dose of praziquantel on Schistosoma mansoni-induced hepatosplenic lesions in northern Uganda.
Topics: Adolescent; Adult; Age Factors; Aged; Animals; Child; Child, Preschool; Feces; Female; Humans; Inter | 1999 |
Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers.
Topics: Animals; Drug Resistance; Egypt; Humans; Liver; Male; Mesenteric Veins; Mice; Muscle Contraction; Pr | 1999 |
Praziquantel--its use, cost and possible development of resistance.
Topics: Africa; Animals; Anthelmintics; Child; Drug Resistance; Female; Humans; Oxamniquine; Praziquantel; P | 1999 |
Increase of intestinal schistosomiasis after praziquantel treatment in a Schistosoma haematobium and Schistosoma mansoni mixed focus.
Topics: Animals; Cohort Studies; Delivery of Health Care; Geography; Humans; Intestinal Diseases, Parasitic; | 1999 |
The epidemiology of a recent focus of mixed Schistosoma haematobium and Schistosoma mansoni infections around the 'Lac de Guiers' in the Senegal River Basin, Senegal.
Topics: Adolescent; Adult; Age Factors; Animals; Biomphalaria; Child; Child, Preschool; Disease Vectors; Fec | 1999 |
[Flu-like infection and liver disease after a stay in the tropics].
Topics: Adult; Africa, Southern; Anthelmintics; Biopsy; Clinical Enzyme Tests; Diagnosis, Differential; Fece | 1999 |
Cytokine control of the granulomatous response in Schistosoma mansoni-infected baboons: role of exposure and treatment.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Cytokines; Disease Models, Animal; Feces; Granulo | 1999 |
The contribution of host-related factors to low cure rates of praziquantel for the treatment of Schistosoma mansoni in Senegal.
Topics: Adult; Age Factors; Animals; Anthelmintics; Antigens, Helminth; Child; Cohort Studies; Feces; Female | 1999 |
Acute pulmonary schistosomiasis in travelers returning from Lake Malawi, sub-Saharan Africa.
Topics: Acute Disease; Adult; Female; Fresh Water; Humans; Lung Diseases, Parasitic; Male; Praziquantel; Sch | 1999 |
Simple school questionnaires can map both Schistosoma mansoni and Schistosoma haematobium in the Democratic Republic of Congo.
Topics: Adolescent; Animals; Anthelmintics; Democratic Republic of the Congo; Feces; Female; Hematuria; Huma | 2000 |
Detection of praziquantel resistance in schistosomes.
Topics: Animals; Drug Resistance; Humans; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; | 2000 |
Correlation between infection intensity, serum immunoglobulin profile, cellular immunity and the efficacy of treatment with praziquantel in murine schistosomiasis mansoni.
Topics: Animals; Body Burden; Enzyme-Linked Immunosorbent Assay; Granuloma; Immunity, Cellular; Immunoglobul | 2000 |
Schistosoma mansoni in mice: the pattern of primary cercarial exposure determines whether a secondary infection post-chemotherapy elicits a T helper 1- or a T helper 2-associated immune response.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Cells, Cultured; Concanavalin A; Culture Media; C | 2000 |
A comparative analysis of the cost-effectiveness of treatment based on parasitological and symptomatic screening for Schistosoma mansoni in Burundi.
Topics: Adolescent; Adult; Animals; Burundi; Child; Cost-Benefit Analysis; Drug Costs; Endemic Diseases; Fec | 2000 |
Experimental trials of an artemisinin derivative in treatment of Schistosoma mansoni infected mice.
Topics: Animals; Anthelmintics; Artemisinins; Mice; Praziquantel; Schistosomiasis mansoni; Sesquiterpenes | 2000 |
Effect of a combination of the new antischistosomal drug Ro 15-5458 and praziquantel on different strains of Schistosoma mansoni infected mice.
Topics: Acridines; Animals; Antiplatyhelmintic Agents; Dose-Response Relationship, Drug; Drug Combinations; | 2000 |
Tegumental changes in adult Schistosoma mansoni harboured in mice treated with praziquantel enantiomers.
Topics: Animals; Anthelmintics; Female; Male; Mice; Microscopy, Electron, Scanning; Optical Rotation; Praziq | 2000 |
Histological assessment of tissue repair after treatment of human schistosomiasis.
Topics: Adult; Animals; Anthelmintics; Cricetinae; Dogs; Egypt; Fibrosis; Humans; Kidney Glomerulus; Liver; | 2000 |
Effect of Schistosoma mansoni infection and treatment on drug metabolizing enzymes.
Topics: Alanine Transaminase; Animals; Cytochrome P-450 Enzyme System; Feces; Liver; Male; Mice; Microsomes, | 2000 |
Effect of combined praziquantel and recombinant glutathione S-transferase on resistance to reinfection in murine Schistosomiasis mansoni.
Topics: Animals; Anthelmintics; Antibodies, Helminth; Drug Therapy, Combination; Glutathione Transferase; Im | 2000 |
The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals.
Topics: Adult; Animals; Anthelmintics; Antigens, Helminth; Feces; HIV Infections; HIV-1; Humans; Male; Paras | 2000 |
The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals.
Topics: Adult; Animals; Anthelmintics; Antigens, Helminth; Feces; HIV Infections; HIV-1; Humans; Male; Paras | 2000 |
The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals.
Topics: Adult; Animals; Anthelmintics; Antigens, Helminth; Feces; HIV Infections; HIV-1; Humans; Male; Paras | 2000 |
The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals.
Topics: Adult; Animals; Anthelmintics; Antigens, Helminth; Feces; HIV Infections; HIV-1; Humans; Male; Paras | 2000 |
Praziquantel-induced tegumental damage in vitro is diminished in schistosomes derived from praziquantel-resistant infections.
Topics: Animals; Anthelmintics; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resista | 2001 |
Effect of praziquantel treatment on the activities of some liver microsomal enzymes in mice infected with Schistosoma mansoni.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Antiplatyhelmintic Agents; gamma-Glutamyltr | 2001 |
Some aspects in the control of schistosomosis and soil-transmitted helminthosis in Yemeni children.
Topics: Adolescent; Albendazole; Analysis of Variance; Anthelmintics; Antiprotozoal Agents; Child; Child, Pr | 2001 |
Relative contribution of day-to-day and intra-specimen variation in faecal egg counts of Schistosoma mansoni before and after treatment with praziquantel.
Topics: Adult; Animals; Anthelmintics; Child; Cote d'Ivoire; Feces; Female; Humans; Male; Parasite Egg Count | 2001 |
Photo quiz: cerebral S. mansoni infection.
Topics: Adult; Animals; Brain; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Neuroschistosomi | 2001 |
Stability and reproductive fitness of Schistosoma mansoni isolates with decreased sensitivity to praziquantel.
Topics: Animals; Anthelmintics; Antibodies, Monoclonal; Antigens, Protozoan; Drug Resistance; Feces; Female; | 2001 |
Fulminant hepatitis associated with Schistosoma mansoni.
Topics: Adolescent; Adrenal Cortex Hormones; Animals; Biopsy; Hepatitis; Humans; Liver; Male; Praziquantel; | 2001 |
[Reinfection with Schistosoma haematobium and mansoni despite repeated praziquantel office treatment in Niger, Mali].
Topics: Adolescent; Age Distribution; Agriculture; Anthelmintics; Child; Female; Humans; Incidence; Male; Ma | 2000 |
Cellular immune responses of schistosomiasis patients are altered by human immunodeficiency virus type 1 coinfection.
Topics: Adolescent; Adult; Animals; Anthelmintics; CD4 Lymphocyte Count; Cells, Cultured; Cytokines; HIV Inf | 2001 |
Effect of combined treatment with praziquantel and artemether on Schistosoma japonicum and Schistosoma mansoni in experimentally infected animals.
Topics: Administration, Oral; Animals; Anthelmintics; Artemether; Artemisinins; Cricetinae; Disease Models, | 2001 |
In vitro responses of praziquantel-resistant and -susceptible Schistosoma mansoni to praziquantel.
Topics: Animals; Anthelmintics; Drug Resistance; Female; Kinetics; Male; Mice; Parasite Egg Count; Parasitic | 2001 |
Replacing oxamniquine by praziquantel against Schistosoma mansoni infection in a rural community from the sugar-cane zone of Northeast Brazil: an epidemiological follow-up.
Topics: Animals; Anthelmintics; Brazil; Crops, Agricultural; Follow-Up Studies; Humans; Oxamniquine; Parasit | 2001 |
Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence.
Topics: Animals; Anthelmintics; Disease Models, Animal; Disease Outbreaks; Drug Resistance; Feces; Humans; M | 2001 |
The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice.
Topics: Analysis of Variance; Animals; Anthelmintics; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Mic | 2002 |
Biological characteristics of praziquantel-resistant and -susceptible isolates of Schistosoma mansoni.
Topics: Animals; Anthelmintics; Biomphalaria; Disease Vectors; Drug Resistance; Feces; Mice; Parasite Egg Co | 2001 |
Factors associated with Schistosoma mansoni infection 5 years after selective treatment in a low endemic area in Brazil.
Topics: Adolescent; Adult; Anthelmintics; Brazil; Child; Child, Preschool; Female; Humans; Infant; Male; Mid | 2002 |
Schistosomal myelopathy: urologic manifestations and urodynamic findings.
Topics: Acute Disease; Adult; Anthelmintics; Chronic Disease; Female; Humans; Male; Middle Aged; Praziquante | 2002 |
Age- and sex-related differences in antibody responses against Schistosoma mansoni soluble egg antigen in a cohort of school children in Ethiopia.
Topics: Adolescent; Age Factors; Animals; Antibodies, Helminth; Antigens, Helminth; Child; Cohort Studies; E | 2001 |
Evaluation of staff performance and material resources for integrated schistosomiasis control in northern Senegal.
Topics: Anthelmintics; Employee Performance Appraisal; Health Education; Health Personnel; Health Resources; | 2002 |
Effect of combined chemotherapy and anti-inflammatory drugs on murine schistosomiasis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Helminth; Drug Therapy, Combination; G | 2002 |
Altered response of strain of Schistosoma mansoni to oxamniquine and praziquantel.
Topics: Animals; Drug Resistance; Female; Humans; Mice; Oxamniquine; Praziquantel; Schistosoma mansoni; Schi | 2002 |
Reduction in the prevalence and intensity of hookworm infections after praziquantel treatment for schistosomiasis infection.
Topics: Adolescent; Ancylostomatoidea; Animals; Anthelmintics; Child; Cote d'Ivoire; Feces; Female; Hookworm | 2002 |
Polyparasitism with Schistosoma mansoni, geohelminths, and intestinal protozoa in rural Côte d'Ivoire.
Topics: Adolescent; Adult; Age Factors; Aged; Animals; Child; Child, Preschool; Cote d'Ivoire; Feces; Female | 2002 |
Cross sectional study of schistosomiasis among military recruits in Alexandria.
Topics: Cross-Sectional Studies; Egypt; Feces; Military Personnel; Parasite Egg Count; Population Surveillan | 1992 |
Efficacy of praziquantel treatment of schistosomiasis in a non-endemic country: a follow-up of parasitological, clinical and immunological parameters.
Topics: Adult; Animals; Antibodies, Helminth; Cohort Studies; Colon; Feces; Humans; Male; Praziquantel; Schi | 1992 |
Experimental schistosomiasis mansoni: modulation of granulomas by inhibition of collagen cross-link formation. Preliminary report.
Topics: Aminopropionitrile; Animals; Collagen; Drug Therapy, Combination; Female; Granuloma; Intestinal Dise | 1992 |
Persistence of eggs and hepatic fibrosis after treatment of Schistosoma mansoni-infected mice.
Topics: Analysis of Variance; Animals; Benzenesulfonates; Collagen; Diphenylamine; Feces; Intestines; Isothi | 1992 |
Effect of praziquantel treatment on brain and kidney ATPase activities in healthy and schistosoma mansoni-infected mice.
Topics: Adenosine Triphosphatases; Animals; Brain; Ca(2+) Mg(2+)-ATPase; Kidney; Male; Mice; Praziquantel; S | 1992 |
Experiences with the control of schistosomiasis mansoni in two foci in central Africa.
Topics: Adult; Animals; Biomphalaria; Burundi; Child; Democratic Republic of the Congo; Disease Reservoirs; | 1992 |
Pre- and post-treatment immunodiagnostic evaluation in human schistosomiasis mansoni.
Topics: Adolescent; Adult; Aged; Antibodies, Helminth; Child; Child, Preschool; Drug Evaluation; Enzyme-Link | 1992 |
Assessment of interleukin-1 activity of peritoneal macrophages in mice infected with Schistosoma mansoni before and after praziquantel administration.
Topics: Animals; Cells, Cultured; Interleukin-1; Macrophages; Mice; Praziquantel; Schistosomiasis mansoni | 1992 |
Experimental chemotherapy of Schistosoma mansoni with praziquantel and oxamniquine: differential effect of single or combined formulations of drugs on various strains and on both sexes of the parasite.
Topics: Animals; Dose-Response Relationship, Drug; Drug Combinations; Female; Intestines; Liver; Male; Mice; | 1992 |
Profile of portal hypertension in hepatosplenic schistosomiasis.
Topics: Feces; Hepatomegaly; Humans; Hypertension, Portal; Parasite Egg Count; Praziquantel; Schistosomiasis | 1992 |
Alternate chemotherapy in experimental schistosomiasis.
Topics: Animals; Drug Therapy, Combination; Feces; Mice; Oxamniquine; Parasite Egg Count; Praziquantel; Schi | 1992 |
Selective population chemotherapy among schoolchildren in Beheira governorate: the UNICEF/Arab Republic of Egypt/WHO Schistosomiasis Control Project.
Topics: Adult; Child; Child, Preschool; Egypt; Female; Humans; Infant; Male; Parasite Egg Count; Praziquante | 1992 |
[Acute schistosomiasis in travellers to the tropics].
Topics: Adult; Animals; Antibodies, Helminth; Diagnosis, Differential; Eosinophilia; Feces; Female; Humans; | 1992 |
Circulating schistosomal antigen in diagnosis and assessment of cure in individuals infected with Schistosoma mansoni.
Topics: Adult; Animals; Antigens, Helminth; Child; Enzyme-Linked Immunosorbent Assay; Feces; Female; Humans; | 1992 |
Detection of circulating anodic antigen before and after specific chemotherapy in experimental murine Schistosomiasis mansoni.
Topics: Animals; Antigens, Helminth; Mice; Mice, Inbred Strains; Parasite Egg Count; Praziquantel; Schistoso | 1992 |
Tryptophan metabolism and vitamin B6 nutritional status in patients with schistosomiasis mansoni and in infected mice.
Topics: Adolescent; Adult; Animals; Humans; Male; Mice; Nutritional Status; Praziquantel; Pyridoxal Phosphat | 1992 |
Selective release of a glycosylphosphatidylinositol-anchored antigen from the surface of Schistosoma mansoni.
Topics: Animals; Antigens, Helminth; Antigens, Surface; Female; Glycolipids; Glycosylphosphatidylinositols; | 1991 |
Schistosoma mansoni: angiotensin converting enzyme activity in mice under the influence of praziquantel and/or captopril.
Topics: Animals; Captopril; Drug Therapy, Combination; Granuloma; Intestines; Liver; Liver Diseases, Parasit | 1991 |
Schistosoma mansoni: larval damage and role of effector cell(s) in the synergy between vaccine immunity and praziquantel treatment.
Topics: Animals; Disease Models, Animal; Eosinophils; Female; Guinea Pigs; Larva; Leukocyte Count; Mice; Mic | 1991 |
Diagnosis of human schistosomiasis by detection of circulating cathodic antigen with a monoclonal antibody.
Topics: Adolescent; Adult; Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens, Helminth; Child; | 1991 |
Scanning electron microscopy of the tegumental surface of in vivo treated Schistosoma mansoni (Saudi Arabian geographical strain) with oxamniquine and praziquantel.
Topics: Animals; Mice; Microscopy, Electron, Scanning; Oxamniquine; Praziquantel; Schistosoma mansoni; Schis | 1991 |
Immunological analysis of cloned Schistosoma mansoni antigens Sm31 and Sm32 with sera of schistosomiasis patients.
Topics: Adolescent; Adult; Animals; Antibodies, Helminth; Antigens, Helminth; Blotting, Western; Child; Clon | 1991 |
Schistosoma mansoni and S. japonicum: decline of antibodies against diagnostic adult worm antigens (Sm31/32) following praziquantel treatment of mice.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Blotting, Western; Cysteine Endopeptidases; Enzym | 1991 |
Effect of praziquantel on pancreatic histopathological changes in experimental schistosomiasis mansoni.
Topics: Animals; Mice; Pancreas; Praziquantel; Schistosomiasis mansoni | 1991 |
Effect of praziquantel therapy on testes of mice infected with Schistosoma mansoni.
Topics: Animals; Male; Mice; Praziquantel; Schistosomiasis mansoni; Spermatogenesis; Testis | 1991 |
Assessment of cure in schistosomiasis patients after chemotherapy with praziquantel by quantitation of circulating anodic antigen (CAA) in urine.
Topics: Adolescent; Adult; Animals; Antigens, Helminth; Child; Creatinine; Enzyme-Linked Immunosorbent Assay | 1991 |
Efficacy of alternating therapy with oxamniquine and praziquantel to treat Schistosoma mansoni in children following failure of first treatment.
Topics: Adolescent; Animals; Child; Drug Therapy, Combination; Feces; Humans; Male; Mice; Oxamniquine; Paras | 1991 |
Impaired balance of interleukin-4 and interferon-gamma production in infections with Schistosoma mansoni and intestinal nematodes.
Topics: Female; Humans; Immunoglobulin E; Interferon-gamma; Interleukin-4; Intestines; Male; Mebendazole; Ne | 1991 |
Association of the therapeutic activity of praziquantel with the reversal of Symmers' fibrosis induced by Schistosoma mansoni.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Female; Hepatomegaly; Humans; Liver Cirrhos | 1991 |
Repeated community-based chemotherapy for the control of Schistosoma mansoni: effect of screening and selective treatment on prevalences and intensities of infection.
Topics: Adolescent; Adult; Age Factors; Burundi; Child; Child, Preschool; Feces; Humans; Infant; Morbidity; | 1991 |
Isotypic analysis of humoral immune responses in rhesus monkeys to an adult microsomal antigen of Schistosoma mansoni: an indicator of successful treatment.
Topics: Animals; Antibody Formation; Antigens, Helminth; Immunoglobulin A; Immunoglobulin E; Immunoglobulin | 1991 |
Tumour necrosis factor in hepatosplenic schistosomiasis.
Topics: Adolescent; Adult; Aged; Biopterins; Cells, Cultured; Child; Female; Humans; Interleukin-1; Leukocyt | 1990 |
Schistosoma mansoni: stage-dependent damage after in vivo treatment with praziquantel.
Topics: Animals; Female; Male; Mice; Microscopy, Electron; Microscopy, Electron, Scanning; Praziquantel; Sch | 1990 |
Effect of specific chemotherapy on the immune response and resistance to reinfection in experimental Schistosomiasis mansoni.
Topics: Animals; Antibody Formation; Granuloma; Liver Diseases; Mice; Praziquantel; Schistosomiasis mansoni; | 1990 |
Antibody response to Schistosoma mansoni adult worm cysteine proteinases in infected individuals.
Topics: Adolescent; Adult; Aged; Animals; Antibodies, Helminth; Antibody Specificity; Child; Child, Preschoo | 1990 |
Metabolism studies of the antischistosomal drug praziquantel using tandem mass spectrometry: qualitative identification of 17 hydroxylated metabolites from mouse urine.
Topics: Animals; Biotransformation; Estrogens; Female; Hydroxylation; Male; Mass Spectrometry; Mice; Praziqu | 1990 |
Metabolism studies of the antischistosomal drug praziquantel using tandem mass spectrometry: distribution of parent drug and ten metabolites obtained from control and schistosome-infected mouse urine.
Topics: Animals; Biotransformation; Female; Hydroxylation; Male; Mass Spectrometry; Mice; Praziquantel; Schi | 1990 |
Effects of praziquantel and oxamniquine on a Saudi Arabian strain of Schistosoma mansoni in mice.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Mice; Nitroquinolines; Oxamniquine; | 1990 |
Evaluation of UNICEF/Arab Republic of Egypt/WHO schistosomiasis Control Project in Beheira Governorate.
Topics: Child; Egypt; Female; Humans; Male; Mobile Health Units; Parasite Egg Count; Praziquantel; Prevalenc | 1990 |
Schistosoma mansoni: detection of circulating antigens in murine schistosomiasis by antigen-capture sandwich ELISA using a monoclonal antibody.
Topics: Animals; Antibodies, Helminth; Antibodies, Monoclonal; Antigens, Helminth; Enzyme-Linked Immunosorbe | 1990 |
Altered generation of interleukin 1 in chronic human schistosomiasis mansoni.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Cells, Cultured; Child; Chronic Disease; Female; HL | 1990 |
Plasminogen activator activity increases during reversal of hepatic fibrosis in murine schistosomiasis.
Topics: Animals; Female; Liver; Liver Cirrhosis, Experimental; Mice; Plasminogen Activators; Praziquantel; S | 1990 |
Immune dependence of schistosomicidal chemotherapy: an ultrastructural study of Schistosoma mansoni adult worms exposed to praziquantel and immune serum in vivo.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Drug Synergism; Fluorescent Antibody Technique; I | 1990 |
Schistosoma mansoni: histological analysis of the synergistic interaction between vaccine immunity and praziquantel therapy in the lungs of mice.
Topics: Analysis of Variance; Animals; Drug Administration Schedule; Drug Synergism; Female; Immunity; Leuko | 1990 |
Immunodiagnosis of schistosomiasis patients in The Netherlands: comparison of antibody and antigen detection before and after chemotherapy.
Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Enzyme-Linked Immunosorbent Assay; Feces; Fluores | 1990 |
Acute schistosomiasis mansoni in Finnish hunters visiting Africa: need for appropriate diagnostic serology.
Topics: Adult; Aged; Animals; Antibodies, Helminth; Central African Republic; Feces; Finland; Fluorescent An | 1990 |
Intestinal schistosomiasis among children in a labour village of Wonji Sugar Estate, Ethiopia.
Topics: Adolescent; Child; Child, Preschool; Ethiopia; Feces; Humans; Parasite Egg Count; Praziquantel; Prev | 1990 |
Attempts to induce resistance in mice to Schistosoma japonicum and Schistosoma mansoni by exposure to crude schistosome antigens plus cloned glutathione-S-transferases.
Topics: Adjuvants, Immunologic; Animals; Antigens, Helminth; Cloning, Molecular; Cyclosporins; Female; Gluta | 1990 |
Safety and immunogenicity of a recombinant hepatitis B vaccine in patients infected with Schistosoma mansoni.
Topics: Adolescent; Adult; Child; Hepatitis B Antibodies; Hepatitis B Vaccines; Hepatitis B virus; Humans; M | 1990 |
Acute schistosomiasis in travellers returning from Africa.
Topics: Botswana; Cote d'Ivoire; Fresh Water; Humans; Praziquantel; Schistosomiasis mansoni; Travel; United | 1990 |
Effect of praziquantel treatment on lung-stage larvae of Schistosoma mansoni in vivo.
Topics: Animals; Antigens, Helminth; Antigens, Surface; Aprotinin; Disease Models, Animal; Dose-Response Rel | 1989 |
[Therapeutic management of schistosomiasis as an imported disease in The Netherlands].
Topics: Anthelmintics; Humans; Praziquantel; Schistosomiasis haematobia; Schistosomiasis mansoni | 1989 |
A study of the ultrastructure of the intestines of mice experimentally infected with S. mansoni and treated with praziquantel.
Topics: Animals; Intestines; Mice; Microscopy, Electron; Praziquantel; Schistosomiasis mansoni | 1989 |
Role of host antibody in the chemotherapeutic action of praziquantel against Schistosoma mansoni: identification of target antigens.
Topics: Animals; Antibodies, Helminth; Antibodies, Monoclonal; Antigens, Helminth; Fluorescent Antibody Tech | 1989 |
Praziquantel and acute urban schistosomiasis.
Topics: Adolescent; Animals; Child; Egypt; Female; Humans; Male; Praziquantel; Schistosoma mansoni; Schistos | 1989 |
Ultrasonographic profile of the liver and caliber of portal vein after oral antibilharzial drugs.
Topics: Adult; Humans; Liver; Male; Nitroquinolines; Oxamniquine; Portal Vein; Praziquantel; Schistosomiasis | 1989 |
Effect of a mass treatment with praziquantel on the excretion in urine of a polysaccharide antigen used for diagnosis of schistosomiasis due to S. mansoni in Cameroon.
Topics: Age Factors; Animals; Antigens, Helminth; Cameroon; Feces; Female; Hemagglutination Tests; Humans; M | 1989 |
Eight years of targeted mass treatment of Schistosoma mansoni infection in Maniema, Zaire.
Topics: Animals; Democratic Republic of the Congo; Hepatomegaly; Humans; Praziquantel; Schistosomiasis manso | 1989 |
Prevalence and control of Schistosoma haematobium infections in the Amran subprovince of the Yemen Arab Republic.
Topics: Adolescent; Animals; Biomphalaria; Bulinus; Child; Cross-Sectional Studies; Female; Humans; Male; Mo | 1989 |
Efficiency of focal molluscicide treatment against schistosomiasis reinfection in an irrigation scheme and in a small dams area in Mali. Preliminary communication.
Topics: Animals; Disease Vectors; Fresh Water; Humans; Mali; Molluscacides; Praziquantel; Recurrence; Schist | 1989 |
A comparison of the antischistosomal effect of levo- and dextro-praziquantel on Schistosoma japonicum and S. mansoni in mice.
Topics: Administration, Oral; Animals; Drug Evaluation, Preclinical; Feces; Female; Male; Mice; Mice, Inbred | 1989 |
Schistosoma japonicum and S. mansoni: ultrastructural damage in the tegument and reproductive organs after treatment with levo- and dextro-praziquantel.
Topics: Animals; Drug Evaluation, Preclinical; Female; Male; Mice; Mice, Inbred ICR; Microscopy, Electron; M | 1989 |
Schistosoma mansoni: enhanced efficacy of praziquantel treatment in immune mice.
Topics: Analysis of Variance; Animals; Female; Immunity, Active; Male; Mice; Mice, Inbred CBA; Praziquantel; | 1989 |
Schistosoma mansoni: experimental chemoprophylaxis in mice using oral anti-penetration agents.
Topics: Administration, Oral; Animals; Castor Oil; Glycerol; Mice; Mice, Inbred ICR; Polyethylene Glycols; P | 1989 |
Effect of praziquantel on the migration and survival of developmental stages of Schistosoma mansoni in mice.
Topics: Animals; Autoradiography; Female; Mice; Mice, Inbred CBA; Praziquantel; Schistosoma mansoni; Schisto | 1989 |
Release of interleukin 2 and gamma interferon by peripheral mononuclear cells in human Schistosoma mansoni infection normalizes after chemotherapy.
Topics: Adolescent; Adult; Aged; Antigens, Helminth; Child; Female; Humans; Hypersensitivity, Delayed; Inter | 1989 |
Acute schistosomiasis (Katayama fever): corticosteroid as adjunct therapy.
Topics: Adjuvants, Pharmaceutic; Adult; Humans; Male; Praziquantel; Prednisolone; Schistosomiasis mansoni | 1989 |
T cell phenotype alterations in hepatosplenic schistosomiasis mansoni normalize after chemotherapy.
Topics: Adolescent; Adult; Aged; Antigens, CD; Child; Female; Humans; Liver Diseases; Lymphocyte Activation; | 1989 |
Effect of praziquantel on the eggs of Schistosoma mansoni, with a note on the implications for managing central nervous system schistosomiasis.
Topics: Animals; Brain Diseases; Feces; Mice; Ovum; Parasite Egg Count; Praziquantel; Schistosoma mansoni; S | 1989 |
Levamisole restored the compromised state of immunity after specific chemotherapy in experimental schistosomiasis mansoni.
Topics: Adjuvants, Immunologic; Animals; Drug Therapy, Combination; Granuloma; Hypersensitivity, Delayed; Hy | 1989 |
A new approach to the treatment of acute schistosomiasis.
Topics: Acute Disease; Adolescent; Adult; Animals; Child; Child, Preschool; Dexamethasone; Drug Synergism; D | 1989 |
Schistosomiasis in expatriates returning to Britain from the tropics: a controlled study.
Topics: Adolescent; Adult; Africa; Egypt; Eosinophilia; Female; Humans; Immunoenzyme Techniques; Male; Middl | 1986 |
Effect of antischistosomal chemotherapy on prevalence of Symmers' periportal fibrosis in Sudanese villages.
Topics: Adolescent; Adult; Aged; Child; Epidemiologic Methods; Humans; Liver Cirrhosis; Middle Aged; Praziqu | 1988 |
Liver involvement in human schistosomiasis mansoni. Regression of immunological and biochemical disease markers after specific treatment.
Topics: Adolescent; Adult; Animals; Antibodies, Helminth; beta 2-Microglobulin; Biopterins; Child; Child, Pr | 1988 |
Immune complex arthritis in a patient with Schistosoma mansoni infection.
Topics: Adult; Antigen-Antibody Complex; Antigens, Protozoan; Arthritis, Infectious; Humans; Immune Complex | 1986 |
Effects of anti-schistosomal chemotherapy on immune responses, protection and immunity. I. Changes in cellular and humoral responses.
Topics: Animals; Antibodies; Antibody Formation; Female; Granuloma; Hypersensitivity, Delayed; Immunity; Imm | 1986 |
Effects of anti-schistosomal chemotherapy on immune responses, protection and immunity. II. Concomitant immunity and immunization with irradiated cercariae.
Topics: Animals; Antigens, Helminth; Female; Immunization; Male; Mice; Praziquantel; Schistosoma mansoni; Sc | 1986 |
Effects of anti-schistosomal chemotherapy on immune responses, protection and immunity. III. An effective regimen of praziquantel does not alter immune capabilities of normal mice.
Topics: Animals; Antibody Formation; Female; Hypersensitivity, Delayed; Immunity, Cellular; Immunization; Le | 1986 |
Praziquantel in the acute porphyrias.
Topics: Adult; Humans; Male; Porphyrias; Praziquantel; Schistosomiasis mansoni | 1986 |
Schistosoma mansoni: chemotherapy of infections of different ages.
Topics: Animals; Antimony Potassium Tartrate; Diphenylamine; Female; Hycanthone; Isothiocyanates; Mice; Mice | 1986 |
Histopathological changes in experimental schistosomiasis mansoni before and after praziquantel therapy.
Topics: Animals; Cricetinae; Intestines; Kidney; Liver; Mesocricetus; Myocardium; Praziquantel; Schistosomia | 1986 |
The efficacy of praziquantel in Egyptian schistosomiasis.
Topics: Adolescent; Adult; Child; Feces; Female; Humans; Male; Praziquantel; Schistosomiasis haematobia; Sch | 1986 |
Enzyme linked immunosorbent assay for the evaluation of praziquantel therapy in different groups of bilharzial patients.
Topics: Antibodies; Antigens, Helminth; Enzyme-Linked Immunosorbent Assay; Humans; Praziquantel; Schistosoma | 1986 |
Blood picture and liver function tests before and after praziquantel therapy of Egyptian bilharzial patients.
Topics: Blood Cell Count; Humans; Liver Function Tests; Praziquantel; Schistosomiasis haematobia; Schistosom | 1986 |
[Effectiveness of praziquantel as an antihelmintic agent in the treatment of bilharziasis].
Topics: Adolescent; Child; Child, Preschool; Congo; Humans; Pilot Projects; Praziquantel; Schistosoma haemat | 1986 |
Schistosomiasis in a mining area: intersectoral implications.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Cost-Benefit Analysis; Democratic Republic of t | 1986 |
Study of some immunopharmacological properties of praziquantel in experimental schistosomiasis mansoni.
Topics: Animals; Antigen-Antibody Reactions; Fluorescent Antibody Technique; Granuloma; Hypersensitivity, De | 1986 |
[Kinetics of the antibody level in schistosomiasis under chemotherapy].
Topics: Adolescent; Adult; Antibody Formation; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; | 1986 |
Evaluation of praziquantel efficiency in the treatment of schistosomiasis.
Topics: Adolescent; Adult; Animals; Female; Humans; Male; Praziquantel; Schistosomiasis haematobia; Schistos | 1986 |
[Sero-epidemiological study of intestinal bilharziasis in Ampefy (Lake Itasy, Madagascar)].
Topics: Adolescent; Age Factors; Antibodies; Child; Child, Preschool; Feces; Female; Fluorescent Antibody Te | 1986 |
[Serodiagnosis of bilharziasis caused by Schistosoma mansoni using the ELISA technic in Madagascar].
Topics: Adolescent; Child; Enzyme-Linked Immunosorbent Assay; Feces; Female; Humans; Madagascar; Male; Prazi | 1986 |
Acute schistosomiasis (Katayama fever): clinical deterioration after chemotherapy.
Topics: Acute Disease; Adult; Female; Humans; Male; Niridazole; Praziquantel; Prednisolone; Schistosomiasis | 1987 |
Ileocolonic schistosomiasis presenting as lymphoma.
Topics: Adult; Colonic Diseases; Diagnosis, Differential; Humans; Ileal Diseases; Ileal Neoplasms; Lymphoma; | 1987 |
The chemotherapeutic effect of praziquantel against Schistosoma mansoni is dependent on host antibody response.
Topics: Animals; Antibodies; Antibody Formation; Antigens, Helminth; B-Lymphocytes; Erythrocytes; Immunizati | 1987 |
Schistosoma mansoni: structural damage and tegumental repair after in vivo treatment with praziquantel.
Topics: Animals; Female; Male; Mice; Microscopy, Electron; Microscopy, Electron, Scanning; Organoids; Praziq | 1987 |
Immune responses and immunoregulation in relation to human schistosomiasis in Egypt. III. Immunity and longitudinal studies of in vitro responsiveness after treatment.
Topics: Adolescent; Adult; Antigens, Helminth; Child; Female; Humans; Immunity; Longitudinal Studies; Lympho | 1986 |
Schistosomiasis control in the southern province of Saudi Arabia.
Topics: Animals; Disease Vectors; Humans; Praziquantel; Saudi Arabia; Schistosomiasis haematobia; Schistosom | 1987 |
Effect of praziquantel on certain immune responses of schistosomal Egyptian patients. I. Changes of specific immunoglobulins.
Topics: Adolescent; Child; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin E; Immunoglobulin G; Im | 1987 |
Effect of praziquantel on certain immune responses of schistosomal Egyptian patients. II. Cell-mediated lymphoproliferative response.
Topics: Adolescent; Adult; Antigens, Helminth; Child; Concanavalin A; Humans; Immunity, Cellular; Lymphocyte | 1987 |
Immunity after treatment of human schistosomiasis mansoni. III. Long-term effects of treatment and retreatment.
Topics: Adolescent; Adult; Age Factors; Child; Female; Humans; Immunity; Immunity, Innate; Male; Middle Aged | 1987 |
Report of an independent evaluation mission on the National Bilharzia Control Program, Egypt, 1985 (abridged version).
Topics: Animals; Costs and Cost Analysis; Disease Vectors; Egypt; Government Agencies; Humans; Molluscacides | 1987 |
Reduction in prevalence, intensity of infection and morbidity due to Schistosoma mansoni infection in a community following treatment with praziquantel.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Hepatomegaly; Humans; Infant; Male; Middle Aged; | 1987 |
[Schistosoma mansoni in the ovary].
Topics: Adult; Animals; Endometriosis; Female; Humans; Ovarian Diseases; Praziquantel; Schistosoma mansoni; | 1987 |
Experience with praziquantel at a lower dose in Kenya.
Topics: Adolescent; Adult; Child; Humans; Kenya; Middle Aged; Praziquantel; Schistosomiasis mansoni | 1987 |
Praziquantel in acute schistosomiasis.
Topics: Animals; Antibodies, Helminth; Child; Dexamethasone; Humans; Male; Praziquantel; Schistosoma mansoni | 1987 |
The status of schistosomiasis before and after treatment among school pupils in a village in the Nile Delta, Egypt.
Topics: Adolescent; Child; Egypt; Female; Humans; Male; Praziquantel; Schistosomiasis haematobia; Schistosom | 1988 |
Praziquantel in treatment of S. mansoni and S. haematobium infections.
Topics: Adolescent; Adult; Female; Humans; Male; Praziquantel; Schistosomiasis haematobia; Schistosomiasis m | 1988 |
[Pulmonary bilharziasis due to Schistosoma mansoni simulating Carrington's disease].
Topics: Diagnosis, Differential; Female; Humans; Lung Diseases, Parasitic; Middle Aged; Praziquantel; Pulmon | 1988 |
Effect of praziquantel on Schistosoma mansoni eggs: leucine aminopeptidase (LAP) activity and anti-LAP antibodies.
Topics: Animals; Antibodies, Helminth; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assa | 1988 |
Immune response in chronic Schistosomiasis haematobium and mansoni. Reversibility of alterations after anti-parasitic treatment with praziquantel.
Topics: Antibodies, Helminth; Antibody Formation; Child; Humans; Male; Praziquantel; Schistosomiasis haemato | 1988 |
Zinc and praziquantel on the pathogenesis of hepatosplenomegaly in experimental mansoniasis.
Topics: Animals; Hepatomegaly; Mice; Praziquantel; Schistosomiasis mansoni; Splenomegaly; Zinc | 1988 |
Effect of praziquantel on hepatic fibrosis in experimental Schistosomiasis mansoni.
Topics: Animals; Collagen; Electrophoresis, Polyacrylamide Gel; Granuloma; Liver; Liver Cirrhosis; Male; Mic | 1988 |
Experiences with mass chemotherapy in the control of schistosomiasis in Mali.
Topics: Adolescent; Adult; Age Factors; Animals; Child; Child, Preschool; Female; Humans; Male; Mali; Parasi | 1988 |
Evidence for an immune-dependent action of praziquantel on Schistosoma mansoni in mice.
Topics: Animals; Mice; Mice, Inbred CBA; Praziquantel; Rabbits; Schistosoma mansoni; Schistosomiasis mansoni | 1987 |
The diagnosis and treatment of acute toxaemic schistosomiasis in children.
Topics: Adolescent; Child; Child, Preschool; Counterimmunoelectrophoresis; Humans; Male; Praziquantel; Predn | 1987 |
Comparative effect of tiaprofenic acid and piroxicam alone and as adjuvants to antibilharzial therapy on pulmonary granuloma in unsensitized mice.
Topics: Animals; Drug Therapy, Combination; Granuloma; Hypersensitivity, Delayed; Lung Diseases; Mice; Pirox | 1988 |
Analysis of worm burdens in experimental schistosomiasis.
Topics: Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Male; Mice; Models, Bi | 1988 |
Anti-schistosome chemotherapy enhanced by antibodies specific for a parasite esterase.
Topics: Animals; Antibodies, Helminth; Combined Modality Therapy; Esterases; Fluorescent Antibody Technique; | 1988 |
Effect of anti-schistosomal treatment on schistosomal-specific nephropathy.
Topics: Adult; Antibodies, Helminth; Antigens, Helminth; Female; Follow-Up Studies; Glomerulonephritis; Glom | 1988 |
A comparison of the efficacy and side effects of various regimens of praziquantel for the treatment of schistosomiasis.
Topics: Dose-Response Relationship, Drug; Humans; Praziquantel; Schistosomiasis haematobia; Schistosomiasis | 1988 |
Anti-schistosomal drugs: observations on the mechanism of drug resistance to hycanthone, and on the involvement of host antibodies in the mode of action of praziquantel.
Topics: Animals; Antibodies, Helminth; Antibody-Dependent Cell Cytotoxicity; Drug Resistance; Hycanthone; Mi | 1987 |
Study of the in vitro cell proliferation of lymphocytes from Manson's schistosomiasis patients treated with praziquantel.
Topics: Adolescent; Adult; Cell Division; Female; Humans; Lymphocytes; Male; Middle Aged; Praziquantel; Schi | 1987 |
Specific treatment of advanced schistosomiasis liver disease in man: favourable results.
Topics: Adolescent; Adult; Aged; Child; Drug Evaluation; Female; Hepatitis, Chronic; Hepatomegaly; Humans; L | 1987 |
Circulating antigens for assessing cure in schistosomiasis mansoni.
Topics: Adolescent; Adult; Antibodies, Helminth; Antigens, Helminth; Child; Enzyme-Linked Immunosorbent Assa | 1988 |
Efficacy and tolerance of praziquantel in patients with Schistosoma mansoni infection and Symmers' fibrosis: a field study in the Sudan.
Topics: Drug Tolerance; Gallbladder; Humans; Liver Cirrhosis; Portal Vein; Praziquantel; Schistosomiasis man | 1988 |
Hepatic histochemistry and electron microscopy of hamsters infected with S. mansoni and treated with praziquantel therapy.
Topics: Animals; Cricetinae; Liver; Microscopy, Electron; Praziquantel; Schistosomiasis mansoni | 1985 |
Treatment of bilharzial colonic polyposis with praziquantel.
Topics: Adolescent; Adult; Child; Colonic Polyps; Humans; Male; Middle Aged; Praziquantel; Schistosomiasis m | 1985 |
Schistosoma mansoni: reduced efficacy of chemotherapy in infected T-cell-deprived mice.
Topics: Animals; Antilymphocyte Serum; Diphenylamine; Hycanthone; Isothiocyanates; Mice; Mice, Inbred CBA; O | 1985 |
Praziquantel for treatment of schistosomiasis in patients with advanced hepatosplenomegaly.
Topics: Adolescent; Adult; Child; Feces; Hepatitis B Surface Antigens; Hepatomegaly; Humans; Male; Middle Ag | 1985 |