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praziquantel and Onchocerciasis

praziquantel has been researched along with Onchocerciasis in 9 studies

azinox: Russian drug

Onchocerciasis: Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions.

Research Excerpts

ExcerptRelevanceReference
"Two-arm comparative study in northern Ghana integrated praziquantel distribution into an existing lymphatic filariasis and onchocerciasis control programme using Community Directed Distributors."7.77Simultaneous administration of praziquantel, ivermectin and albendazole, in a community in rural northern Ghana endemic for schistosomiasis, onchocerciasis and lymphatic filariasis. ( Aborigo, R; Adjuik, M; Akweongo, P; Amankwa, J; Anto, F; Anyorigiya, T; Asoala, V; Bimi, L; Hodgson, A; Oduro, A, 2011)
"We assessed the impact of three annual vs five semiannual rounds of mass drug administration (MDA) with ivermectin plus albendazole followed by praziquantel for the control or elimination of lymphatic filariasis (LF), onchocerciasis, soil-transmitted helminth (STH) infections and schistosomiasis in Lofa County, Liberia."5.51Community-based trial assessing the impact of annual versus semiannual mass drug administration with ivermectin plus albendazole and praziquantel on helminth infections in northwestern Liberia. ( Bolay, FK; Curtis, K; Eneanya, OA; Fischer, K; Fischer, PU; Gankpala, L; Goss, CW; Gray, EB; Momolu, AT; Nyan, ES; Weil, GJ, 2022)
"Our data suggest that co-administration of ivermectin, albendazole and praziquantel is safe in areas where lymphatic filariasis, soil-transmitted helminthiasis and schistosomiasis are co-endemic and where several rounds of treatment with one or two drugs have been implemented in the past."5.13Triple co-administration of ivermectin, albendazole and praziquantel in zanzibar: a safety study. ( Biswas, G; Bradley, MH; Chitsulo, L; Engels, D; Gabrielli, AF; Haji, HJ; Mohammed, KA; Molyneux, DH; Mubila, L; Savioli, L, 2008)
" The introduction of oxamniquine and praziquantel constitutes a break through in the treatment of intestinal and urogenital schistosomiasis."4.76[Present status of the treatment of helminthiasis]. ( Coulaud, JP, 1984)
"Two-arm comparative study in northern Ghana integrated praziquantel distribution into an existing lymphatic filariasis and onchocerciasis control programme using Community Directed Distributors."3.77Simultaneous administration of praziquantel, ivermectin and albendazole, in a community in rural northern Ghana endemic for schistosomiasis, onchocerciasis and lymphatic filariasis. ( Aborigo, R; Adjuik, M; Akweongo, P; Amankwa, J; Anto, F; Anyorigiya, T; Asoala, V; Bimi, L; Hodgson, A; Oduro, A, 2011)
" Lastly, widespread neurocysticercosis may be a concern in mass treatment programs that provide praziquantel (for managing schistosomiasis) or albendazole (for managing intestinal worms or lymphatic filariasis) because these drugs may kill cerebral cysticerci, resulting in severe adverse events."3.74Could neurocysticercosis be the cause of "onchocerciasis-associated" epileptic seizures? ( Eberhard, M; Habumogisha, P; Katabarwa, M; Lakwo, T; Richards, F, 2008)
"Onchocerciasis is co-endemic with schistosomiasis and intestinal helminths infections, which are all diseases of the rural and the poorest communities in Africa."1.32Integrated community-directed treatment for the control of onchocerciasis, schistosomiasis and intestinal helminths infections in Uganda: advantages and disadvantages. ( Kabatereine, N; Ndyomugyenyi, R, 2003)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's5 (55.56)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Eneanya, OA1
Gankpala, L1
Goss, CW1
Momolu, AT1
Nyan, ES1
Gray, EB1
Fischer, K1
Curtis, K1
Bolay, FK1
Weil, GJ1
Fischer, PU1
Anto, F1
Asoala, V1
Anyorigiya, T1
Oduro, A1
Adjuik, M1
Akweongo, P1
Aborigo, R1
Bimi, L1
Amankwa, J1
Hodgson, A1
Hopkins, DR1
Eigege, A2
Miri, ES1
Gontor, I1
Ogah, G1
Umaru, J2
Gwomkudu, CC1
Mathai, W1
Jinadu, M1
Amadiegwu, S1
Oyenekan, OK1
Korve, K1
Richards, FO1
Ndyomugyenyi, R1
Kabatereine, N1
Mohammed, KA1
Haji, HJ1
Gabrielli, AF1
Mubila, L1
Biswas, G1
Chitsulo, L1
Bradley, MH1
Engels, D1
Savioli, L1
Molyneux, DH1
Pede, E1
Miri, E1
Ogbu Pearce, P1
Jinadu, MY1
Njepuome, AN1
Katabarwa, M1
Lakwo, T1
Habumogisha, P1
Richards, F1
Eberhard, M1
Coulaud, JP1
Forsyth, KP1
Mitchell, GF1
Copeman, DB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Can Anthelminthic Treatment Delay the Progression of HIV? Randomised Open-label Trial Testing Presumptive Anthelminthic Treatment on Progression of HIV in ART-naïve HIV-positive Patients in a Rural African Setting With Presumed High Prevalence of Helminth[NCT00817713]295 participants (Actual)Interventional2009-01-31Terminated (stopped due to Terminated prematurely due to recruitment difficulties. Expansion to more study sites not planned.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for praziquantel and Onchocerciasis

ArticleYear
[Present status of the treatment of helminthiasis].
    Presse medicale (Paris, France : 1983), 1984, Oct-13, Volume: 13, Issue:36

    Topics: Albendazole; Anthelmintics; Benzimidazoles; Cestode Infections; Echinococcosis; Helminthiasis; Human

1984

Trials

2 trials available for praziquantel and Onchocerciasis

ArticleYear
Community-based trial assessing the impact of annual versus semiannual mass drug administration with ivermectin plus albendazole and praziquantel on helminth infections in northwestern Liberia.
    Acta tropica, 2022, Volume: 231

    Topics: Albendazole; Animals; Cross-Sectional Studies; Elephantiasis, Filarial; Helminthiasis; Humans; Iverm

2022
Triple co-administration of ivermectin, albendazole and praziquantel in zanzibar: a safety study.
    PLoS neglected tropical diseases, 2008, Jan-23, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Albendazole; Anthelmintics; Child; Child, Preschool; Drug Therapy, Combination; E

2008

Other Studies

6 other studies available for praziquantel and Onchocerciasis

ArticleYear
Simultaneous administration of praziquantel, ivermectin and albendazole, in a community in rural northern Ghana endemic for schistosomiasis, onchocerciasis and lymphatic filariasis.
    Tropical medicine & international health : TM & IH, 2011, Volume: 16, Issue:9

    Topics: Adolescent; Albendazole; Child; Drug Therapy, Combination; Elephantiasis, Filarial; Endemic Diseases

2011
Lymphatic filariasis elimination and schistosomiasis control in combination with onchocerciasis control in Nigeria.
    The American journal of tropical medicine and hygiene, 2002, Volume: 67, Issue:3

    Topics: Anthelmintics; Elephantiasis, Filarial; Health Education; Health Knowledge, Attitudes, Practice; Hum

2002
Integrated community-directed treatment for the control of onchocerciasis, schistosomiasis and intestinal helminths infections in Uganda: advantages and disadvantages.
    Tropical medicine & international health : TM & IH, 2003, Volume: 8, Issue:11

    Topics: Adolescent; Anthelmintics; Child; Child, Preschool; Community Health Services; Decision Making; Feas

2003
Triple drug administration (TDA), with praziquantel, ivermectin and albendazole, for the prevention of three neglected tropical diseases in Nigeria.
    Annals of tropical medicine and parasitology, 2008, Volume: 102, Issue:2

    Topics: Albendazole; Anthelmintics; Antiparasitic Agents; Cost-Benefit Analysis; Drug Interactions; Drug The

2008
Could neurocysticercosis be the cause of "onchocerciasis-associated" epileptic seizures?
    The American journal of tropical medicine and hygiene, 2008, Volume: 78, Issue:3

    Topics: Albendazole; Animals; Anthelmintics; Epilepsy; Humans; Neurocysticercosis; Onchocerca; Onchocerciasi

2008
Onchocerca gibsoni: increase of circulating egg antigen with chemotherapy in bovines.
    Experimental parasitology, 1984, Volume: 58, Issue:1

    Topics: Animals; Anthelmintics; Antibodies, Monoclonal; Antigens, Surface; Cattle; Diethylcarbamazine; Femal

1984