Page last updated: 2024-11-03

praziquantel and Liver Dysfunction

praziquantel has been researched along with Liver Dysfunction in 23 studies

azinox: Russian drug

Research Excerpts

ExcerptRelevanceReference
"In view of the potential immunosuppressive and regenerative properties of mesenchymal stem cells (MSC), we investigated whether transplantation of adipose tissue-derived stem cells (ASC) could be used to control the granulomatous reaction in the liver of mice infected with Schistosoma mansoni after Praziquantel (PZQ) treatment."7.96Liver damage in schistosomiasis is reduced by adipose tissue-derived stem cell therapy after praziquantel treatment. ( Alves, ÉAR; Bicalho, KA; Birbrair, A; Bozzi, A; Chaves, AT; Corrêa-Oliveira, R; de Goes, AM; Eller, DE; Ferraz, LCN; Gomes, TR; Miranda, VHS; Pascoal Xavier, MA; Silva, CEC, 2020)
"Inflammation of the hepatobiliary system in chronic opisthorchiasis is associated with an elevated level of urinary 8-oxo-7,8 dihydro-2'deoxyguanosine (8-oxodG) during active as well as past exposure to Opisthorchis viverrini infection."7.91Evaluation of a short term effect of praziquantel treatment in opisthorchiasis-induced hepatobiliary inflammation by urinary 8-oxodG. ( Bethony, JM; Chamadol, N; Eamudomkarn, C; Jumnainsong, A; Khuntikeo, N; Loilome, W; Pinlaor, S; Sithithaworn, J; Sithithaworn, P; Techasen, A; Thanan, R; Wangboon, C; Worasith, C; Yongvanit, P, 2019)
"In praziquantel-treated mice (500 mg/kg for 2 days orally), the reduction in the percent resistance (45."5.28Levamisole restored the compromised state of immunity after specific chemotherapy in experimental schistosomiasis mansoni. ( Azab, ME; Botros, SS; el-Garem, A; el-Nahal, HM; Hassan, SI; Shaker, ZA, 1989)
"Mice treated with praziquantel showed a prompt decrease in S."5.27Reversal of hepatic fibrosis after praziquantel therapy of murine schistosomiasis. ( Dunn, MA; Girgis, NI; Ishak, EA; Khayyal, MT; Mansour, MM; Morcos, SH; Saleh, S, 1985)
" The effect of prolonged administration of bevacizumab with praziquantel was also assessed through parasitic load, protective index, granuloma and fibrous tissue evaluation."3.96Bevacizumab as a potential anti-angiogenic therapy in schistosomiasis: A double-edged, but adjustable weapon. ( El-Anwar, N; Hasby Saad, MA, 2020)
"In view of the potential immunosuppressive and regenerative properties of mesenchymal stem cells (MSC), we investigated whether transplantation of adipose tissue-derived stem cells (ASC) could be used to control the granulomatous reaction in the liver of mice infected with Schistosoma mansoni after Praziquantel (PZQ) treatment."3.96Liver damage in schistosomiasis is reduced by adipose tissue-derived stem cell therapy after praziquantel treatment. ( Alves, ÉAR; Bicalho, KA; Birbrair, A; Bozzi, A; Chaves, AT; Corrêa-Oliveira, R; de Goes, AM; Eller, DE; Ferraz, LCN; Gomes, TR; Miranda, VHS; Pascoal Xavier, MA; Silva, CEC, 2020)
"Inflammation of the hepatobiliary system in chronic opisthorchiasis is associated with an elevated level of urinary 8-oxo-7,8 dihydro-2'deoxyguanosine (8-oxodG) during active as well as past exposure to Opisthorchis viverrini infection."3.91Evaluation of a short term effect of praziquantel treatment in opisthorchiasis-induced hepatobiliary inflammation by urinary 8-oxodG. ( Bethony, JM; Chamadol, N; Eamudomkarn, C; Jumnainsong, A; Khuntikeo, N; Loilome, W; Pinlaor, S; Sithithaworn, J; Sithithaworn, P; Techasen, A; Thanan, R; Wangboon, C; Worasith, C; Yongvanit, P, 2019)
"Treatment with praziquantel reduces the prevalence and intensity of Schistosoma mansoni infection."3.70Evidence for a long-term effect of a single dose of praziquantel on Schistosoma mansoni-induced hepatosplenic lesions in northern Uganda. ( Doehring, E; Frenzel, K; Grigull, L; Loroni-Lakwo, T; Ndugwa, CM; Odongo-Aginya, E; Schweigmann, U; Spannbrucker, N; Vester, U, 1999)
"Non steroidal anti-inflammatory drugs (NSAIDs) (tiaprofenic acid and piroxicam have been used alone and as adjuvants to praziquantel in treating hepatic granuloma in Schistosoma mansoni infected mice."3.69Comparative effect of tiaprofenic acid and piroxicam alone and as adjuvants to praziquantel in Schistosoma mansoni infected mice. ( Hegazy, IH; Moussa, SM; Nassar, SH, 1997)
" The efficacy of BAPN, alone or in association with the anti-schistosomal drug, praziquantel (PZQ), was primarily assessed by measuring the reduction in liver and intestinal egg loads in murine schistosomiasis mansoni."3.68Experimental schistosomiasis mansoni: modulation of granulomas by inhibition of collagen cross-link formation. Preliminary report. ( Giboda, M; Julis, I; Vítovec, J; Zenka, J, 1992)
"Peripheral blood T cell phenotypes, CD3-induced mitogenesis and soluble IL 2 receptor and CD8 in sera were studied in intestinal and hepatosplenic Schistosomiasis mansoni before and three to six months after therapy with praziquantel."3.67T cell phenotype alterations in hepatosplenic schistosomiasis mansoni normalize after chemotherapy. ( Bienzle, U; Correia Dacal, AR; Feldmeier, H; Harms, G; Jansen-Rosseck, R; Vergetti de Siqueira, JG; Zwingenberger, K, 1989)
" Unfortunately, it exhibits low oral bioavailability which can compromise its efficacy."1.51Niosomes for enhanced activity of praziquantel against Schistosoma mansoni: in vivo and in vitro evaluation. ( Abd Elazeem, MA; Aboul Asaad, IA; El Maghraby, GM; El-Kowrany, SI; El-Nouby, KA; Zoghroban, HS, 2019)
"Tests for a haemochromatosis gene and its type showed a homozygotic C282Y variant."1.30[Flu-like infection and liver disease after a stay in the tropics]. ( Gehrke, S; Nothdurft, HD; Schneider, M; Stremmel, W, 1999)
"In praziquantel-treated mice, the reduction in the per cent resistance was accompanied by a diminution in the size of hepatic granulomata and its in vivo correlate the delayed foot pad swelling."1.28Effect of specific chemotherapy on the immune response and resistance to reinfection in experimental Schistosomiasis mansoni. ( Azab, ME; Botros, SS; el-Garem, AA; el-Nahal, HM; Hassan, SI; Shaker, ZA, 1990)
"In praziquantel-treated mice (500 mg/kg for 2 days orally), the reduction in the percent resistance (45."1.28Levamisole restored the compromised state of immunity after specific chemotherapy in experimental schistosomiasis mansoni. ( Azab, ME; Botros, SS; el-Garem, A; el-Nahal, HM; Hassan, SI; Shaker, ZA, 1989)
"Mice treated with praziquantel showed a prompt decrease in S."1.27Reversal of hepatic fibrosis after praziquantel therapy of murine schistosomiasis. ( Dunn, MA; Girgis, NI; Ishak, EA; Khayyal, MT; Mansour, MM; Morcos, SH; Saleh, S, 1985)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19905 (21.74)18.7374
1990's8 (34.78)18.2507
2000's1 (4.35)29.6817
2010's6 (26.09)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Atwa, MTM1
Abd-Elrazek, AM1
Salem, NIS1
Hasby Saad, MA1
El-Anwar, N1
Miranda, VHS1
Gomes, TR1
Eller, DE1
Ferraz, LCN1
Chaves, AT1
Bicalho, KA1
Silva, CEC1
Birbrair, A1
Pascoal Xavier, MA1
de Goes, AM1
Corrêa-Oliveira, R1
Alves, ÉAR1
Bozzi, A1
Abd El-Aal, NF1
Hamza, RS1
Magdy, M1
Wangboon, C1
Worasith, C1
Thanan, R1
Eamudomkarn, C1
Techasen, A1
Sithithaworn, J1
Loilome, W1
Chamadol, N1
Pinlaor, S1
Jumnainsong, A1
Yongvanit, P1
Khuntikeo, N1
Bethony, JM1
Sithithaworn, P1
Zoghroban, HS1
El-Kowrany, SI1
Aboul Asaad, IA1
El Maghraby, GM1
El-Nouby, KA1
Abd Elazeem, MA1
Bustinduy, AL1
Luzinda, K1
Mpoya, S1
Gothard, P1
Stone, N1
Wright, S1
Stothard, JR1
Argirovic, N1
Caselitz, M1
Mohren, W1
Cruz Cordero, F1
Huber, J1
Wagner, S1
Zhu, ZJ1
Shen, ZY1
Gao, W1
Zheng, H1
Deng, YL1
Pan, C1
Sun, LY1
Zeng, ZG1
Sun, JS1
Traore, HA1
Maiga, MY1
Sogodogo, S1
Dembele, M1
Sidibe, TA1
Diallo, D1
Diallo, AN1
Guindo, A1
Pichard, E1
Doumbo, O1
El-Banhawey, MA1
Ashry, MA1
El-Ansary, AK1
Aly, SA1
Mehlhorn, H1
Frenkel, JK1
Andrews, P1
Thomas, H1
Johansen, MV1
Monrad, J1
Christensen, NO1
Lindberg, R1
Botros, SS3
Doughty, BL1
Shaker, ZA3
Akl, MM1
Sharmy, R1
Diab, TM1
Hassanein, HI1
Hegazy, IH1
Nassar, SH1
Moussa, SM1
Frenzel, K1
Grigull, L1
Odongo-Aginya, E1
Ndugwa, CM1
Loroni-Lakwo, T1
Schweigmann, U1
Vester, U1
Spannbrucker, N1
Doehring, E1
Schneider, M1
Gehrke, S1
Nothdurft, HD1
Stremmel, W1
Giboda, M1
Zenka, J1
Julis, I1
Vítovec, J1
Hassan, SI2
el-Nahal, HM2
Azab, ME2
el-Garem, AA1
Zwingenberger, K1
Harms, G1
Vergetti de Siqueira, JG1
Correia Dacal, AR1
Jansen-Rosseck, R1
Bienzle, U1
Feldmeier, H1
el-Garem, A1
Thammapalerd, N1
Tharavanij, S1
Nacapunchai, D1
Bunnag, D1
Radomyos, P1
Prasertsiriroj, V1
Morcos, SH1
Khayyal, MT1
Mansour, MM1
Saleh, S1
Ishak, EA1
Girgis, NI1
Dunn, MA1

Other Studies

23 other studies available for praziquantel and Liver Dysfunction

ArticleYear
Dandelion (Taraxacum officinale) Improves the Therapeutic Efficiency of Praziquantel in Experimental Schistosomiasis.
    Acta parasitologica, 2022, Volume: 67, Issue:2

    Topics: Animals; Anthelmintics; Granuloma; Liver; Liver Diseases; Mice; Plant Extracts; Praziquantel; Schist

2022
Bevacizumab as a potential anti-angiogenic therapy in schistosomiasis: A double-edged, but adjustable weapon.
    Parasite immunology, 2020, Volume: 42, Issue:10

    Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Chronic Disease; Granuloma; Liver Diseases; Male; Mic

2020
Liver damage in schistosomiasis is reduced by adipose tissue-derived stem cell therapy after praziquantel treatment.
    PLoS neglected tropical diseases, 2020, Volume: 14, Issue:8

    Topics: Adipose Tissue; Animals; Cell- and Tissue-Based Therapy; Cytokines; Disease Models, Animal; Granulom

2020
Anti-angiogenic and anti-lymphangiogenic role of praziquantel and artemether in experimental mansoniasis.
    Acta parasitologica, 2017, Dec-20, Volume: 62, Issue:4

    Topics: Animals; Artemether; Artemisinins; Female; Granuloma; Liver Diseases; Mice; Praziquantel; Schistosom

2017
Evaluation of a short term effect of praziquantel treatment in opisthorchiasis-induced hepatobiliary inflammation by urinary 8-oxodG.
    Acta tropica, 2019, Volume: 189

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anthelmintics; Biliary Tract Diseases; Biomarkers; Deoxyguanos

2019
Niosomes for enhanced activity of praziquantel against Schistosoma mansoni: in vivo and in vitro evaluation.
    Parasitology research, 2019, Volume: 118, Issue:1

    Topics: Animals; Biological Availability; Female; Humans; Intestines; Liposomes; Liver Diseases; Male; Mice;

2019
Endomyocardial fibrosis (EMF) in a Ugandan child with advanced hepatosplenic schistosomiasis: coincidence or connection?
    The American journal of tropical medicine and hygiene, 2014, Volume: 91, Issue:4

    Topics: Animals; Anthelmintics; Child; Endomyocardial Fibrosis; Feces; Humans; Liver Diseases; Male; Praziqu

2014
[Peranal bleeding and elevated liver function tests in a 33‑year-old refugee from Nigeria].
    Der Internist, 2016, Volume: 57, Issue:8

    Topics: Adult; Anthelmintics; Anus Diseases; Diagnosis, Differential; Hemorrhage; Humans; Liver Diseases; Li

2016
Feasibility of using a liver infected with Clonorchis sinensis for liver transplantation: fourteen cases.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2010, Volume: 16, Issue:12

    Topics: Adult; Animals; Anthelmintics; Clonorchiasis; Clonorchis sinensis; Feasibility Studies; Female; Foll

2010
[Importance of hepatic bilharziasis in liver pathologies in the internal medicine department of the National Hospital of Point "G", Bamako-Mali].
    Dakar medical, 1996, Volume: Spec No

    Topics: Adolescent; Adult; Aged; Anthelmintics; Biopsy; Child; Female; Granuloma; Hepatomegaly; Hospital Dep

1996
Effect of Curcuma longa or parziquantel on Schistosoma mansoni infected mice liver--histological and histochemical study.
    Indian journal of experimental biology, 2007, Volume: 45, Issue:10

    Topics: Alkaline Phosphatase; Animals; Body Weight; Curcuma; Liver Diseases; Male; Mice; Organ Size; Phytoth

2007
Light and electron microscopic studies on Schistosoma mansoni Granulomas of mouse livers following treatment with praziquantel.
    Tropenmedizin und Parasitologie, 1982, Volume: 33, Issue:4

    Topics: Animals; Female; Granuloma; Isoquinolines; Liver; Liver Diseases; Mice; Ovum; Praziquantel; Schistos

1982
Experimental Schistosoma bovis infection in goats: pathological consequences of praziquantel treatment.
    Journal of comparative pathology, 1996, Volume: 115, Issue:1

    Topics: Animals; Antiplatyhelmintic Agents; Female; Goats; Granuloma; Intestines; Liver; Liver Diseases; Lym

1996
Efficacy of an antipathology vaccine in murine schistosomiasis administered with and without chemotherapy.
    International journal of immunopharmacology, 1996, Volume: 18, Issue:12

    Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Female; Granuloma; Immune Tolerance; Immunoglobul

1996
Comparative effect of tiaprofenic acid and piroxicam alone and as adjuvants to praziquantel in Schistosoma mansoni infected mice.
    Journal of the Egyptian Society of Parasitology, 1997, Volume: 27, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclic AMP; Dinoprostone; Drug Therapy, Combinatio

1997
Evidence for a long-term effect of a single dose of praziquantel on Schistosoma mansoni-induced hepatosplenic lesions in northern Uganda.
    The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Animals; Child; Child, Preschool; Feces; Female; Humans; Inter

1999
[Flu-like infection and liver disease after a stay in the tropics].
    Deutsche medizinische Wochenschrift (1946), 1999, Oct-01, Volume: 124, Issue:39

    Topics: Adult; Africa, Southern; Anthelmintics; Biopsy; Clinical Enzyme Tests; Diagnosis, Differential; Fece

1999
Experimental schistosomiasis mansoni: modulation of granulomas by inhibition of collagen cross-link formation. Preliminary report.
    Annals of tropical medicine and parasitology, 1992, Volume: 86, Issue:6

    Topics: Aminopropionitrile; Animals; Collagen; Drug Therapy, Combination; Female; Granuloma; Intestinal Dise

1992
Effect of specific chemotherapy on the immune response and resistance to reinfection in experimental Schistosomiasis mansoni.
    International journal of immunopharmacology, 1990, Volume: 12, Issue:2

    Topics: Animals; Antibody Formation; Granuloma; Liver Diseases; Mice; Praziquantel; Schistosomiasis mansoni;

1990
T cell phenotype alterations in hepatosplenic schistosomiasis mansoni normalize after chemotherapy.
    Immunobiology, 1989, Volume: 179, Issue:4-5

    Topics: Adolescent; Adult; Aged; Antigens, CD; Child; Female; Humans; Liver Diseases; Lymphocyte Activation;

1989
Levamisole restored the compromised state of immunity after specific chemotherapy in experimental schistosomiasis mansoni.
    Immunopharmacology and immunotoxicology, 1989, Volume: 11, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Drug Therapy, Combination; Granuloma; Hypersensitivity, Delayed; Hy

1989
Detection of antibodies against Opisthorchis viverrini in patients before and after treatment with praziquantel.
    The Southeast Asian journal of tropical medicine and public health, 1988, Volume: 19, Issue:1

    Topics: Animals; Antibodies, Helminth; Concanavalin A; Enzyme-Linked Immunosorbent Assay; Hemagglutination T

1988
Reversal of hepatic fibrosis after praziquantel therapy of murine schistosomiasis.
    The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:2

    Topics: Animals; Collagen; Granuloma; Hydroxyproline; Isoquinolines; Liver; Liver Diseases; Male; Mice; Orga

1985