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praziquantel and Inflammation

praziquantel has been researched along with Inflammation in 28 studies

azinox: Russian drug

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"This cohort study assessed urinary eosinophil cationic protein (ECP) as an indicator for urinary tract morbidity and inflammation indication related to single-dose or dual-dose praziquantel (PZQ) treatment."7.85Inflammation dynamics after praziquantel treatment of Schistosoma haematobium reflected by urinary eosinophil cationic protein. ( Fofana, HKM; Keita, AD; Landouré, A; Madsen, H; Reimert, CM; Sacko, M; Stecher, CW; Traoré, MS; Vennervald, BJ; Wilson, S, 2017)
" Aspirin has many properties including anti-inflammation and anti-cancer."7.83Combination of Praziquantel and Aspirin Minimizes Liver Pathology of Hamster Opisthorchis viverrini Infection Associated Cholangiocarcinoma. ( Aukkanimart, R; Boonmars, T; Jiraporn, S; Loilome, W; Nadchanan, W; Namwat, N; Ruangjirachuporn, W; Sriraj, P; Sudsarn, P, 2016)
"Taken together, these data suggest that the combined treatment of PZQ and edelfosine promotes a high decrease in granuloma formation, as well as in the cellular immune response that underlies granuloma development, with changes in the cytokine patterns, and may provide a promising and effective strategy for a prophylactic treatment of schistosomiasis."7.81Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel. ( López-Abán, J; Mollinedo, F; Muro, A; Rojas-Caraballo, J; Varela-M, RE; Yepes, E, 2015)
"A 59-year-old man with known neurocysticercosis developed a large cerebral infarction during praziquantel therapy."7.69Large cerebral infarction during praziquantel therapy in neurocysticercosis. ( Bang, OY; Choi, SA; Heo, JH; Kim, DI, 1997)
"Curcumin-treated groups, with and without PZQ, resulted in higher significant Immunoreactivity score (IRS) for Bcl-2-associated X (BAX) and lower Interleukine- 17A (IL-17A), and Human epidermal growth factor (EGF), compared to the control."5.72Potentiality of curcumin on ISHAK scoring system and the expressions of BAX, IL-17A, and EGF in the treatment ofSchistosoma mansoni infection using Swiss albino mice. ( Abd-Elaal, AA; Amin, NM; El Saftawy, EA; El-Dardiry, MA; Negm, MSI, 2022)
" We investigated systemic inflammation as measured by plasma levels of soluble tumor necrosis factor-alpha receptor II (sTNF-rII), interleukin-8, (IL-8), and IL-10 during schistosomiasis and HIV co-infection and after schistosomiasis treatment."5.13Schistosomiasis and infection with human immunodeficiency virus 1 in rural Zimbabwe: systemic inflammation during co-infection and after treatment for schistosomiasis. ( Butterworth, AE; Deelder, AM; Erikstrup, C; Gerstoft, J; Gomo, E; Kallestrup, P; Ostrowski, SR; Pedersen, BK; Ullum, H; van Dam, GJ; Zinyama-Gutsire, RB, 2008)
" Antischistosomal therapy, praziquantel, used for pulmonary hypertension secondary to schistosomiasis usually has no effect, but it is given to prevent further progression of disease."4.86Pulmonary vascular disease associated with schistosomiasis. ( Butrous, G; Crosby, A; Harhay, MO; Kolosionek, E; Morrell, N, 2010)
" This study aimed to investigate baseline Schistosoma mansoni-Circulating Anodic Antigen (CAA) levels and their association with kidney biomarkers related to podocyte injury and inflammation in long-term follow-up after praziquantel (PZQ) treatment."4.31Subclinical signs of podocyte injury associated with Circulating Anodic Antigen (CAA) in Schistosoma mansoni-infected patients in Brazil. ( Bezerra, FSM; Corstjens, PLAM; Daher, EF; Dam, GJV; Galvão, RLF; Martins, AMC; Meneses, GC; Pinheiro, MCC; Sousa, MS, 2023)
"This cohort study assessed urinary eosinophil cationic protein (ECP) as an indicator for urinary tract morbidity and inflammation indication related to single-dose or dual-dose praziquantel (PZQ) treatment."3.85Inflammation dynamics after praziquantel treatment of Schistosoma haematobium reflected by urinary eosinophil cationic protein. ( Fofana, HKM; Keita, AD; Landouré, A; Madsen, H; Reimert, CM; Sacko, M; Stecher, CW; Traoré, MS; Vennervald, BJ; Wilson, S, 2017)
" Aspirin has many properties including anti-inflammation and anti-cancer."3.83Combination of Praziquantel and Aspirin Minimizes Liver Pathology of Hamster Opisthorchis viverrini Infection Associated Cholangiocarcinoma. ( Aukkanimart, R; Boonmars, T; Jiraporn, S; Loilome, W; Nadchanan, W; Namwat, N; Ruangjirachuporn, W; Sriraj, P; Sudsarn, P, 2016)
"Taken together, these data suggest that the combined treatment of PZQ and edelfosine promotes a high decrease in granuloma formation, as well as in the cellular immune response that underlies granuloma development, with changes in the cytokine patterns, and may provide a promising and effective strategy for a prophylactic treatment of schistosomiasis."3.81Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel. ( López-Abán, J; Mollinedo, F; Muro, A; Rojas-Caraballo, J; Varela-M, RE; Yepes, E, 2015)
"A 59-year-old man with known neurocysticercosis developed a large cerebral infarction during praziquantel therapy."3.69Large cerebral infarction during praziquantel therapy in neurocysticercosis. ( Bang, OY; Choi, SA; Heo, JH; Kim, DI, 1997)
" INTERPRETATION/SIGNIFICANCE: PZQ treatment is as safe and efficacious in children aged 1-5 years as it is in older children aged 6-10 years in whom PZQ is the drug of choice for control of schistosome infections."2.76Schistosoma haematobium treatment in 1-5 year old children: safety and efficacy of the antihelminthic drug praziquantel. ( Appleby, L; Bourke, C; Mduluza, T; Midzi, N; Mitchell, K; Mutapi, F; Nausch, N; Rujeni, N, 2011)
"Curcumin-treated groups, with and without PZQ, resulted in higher significant Immunoreactivity score (IRS) for Bcl-2-associated X (BAX) and lower Interleukine- 17A (IL-17A), and Human epidermal growth factor (EGF), compared to the control."1.72Potentiality of curcumin on ISHAK scoring system and the expressions of BAX, IL-17A, and EGF in the treatment ofSchistosoma mansoni infection using Swiss albino mice. ( Abd-Elaal, AA; Amin, NM; El Saftawy, EA; El-Dardiry, MA; Negm, MSI, 2022)
"Vesical paragonimiasis is an extremely rare form of ectopic infestation caused by Paragonimus spp."1.40Vesical paragonimiasis diagnosed by histopathology: a case report. ( Han, P; Li, X; Liu, L; Wei, Q; Wei, X; Yue, X; Zhu, Y, 2014)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's3 (10.71)18.2507
2000's2 (7.14)29.6817
2010's16 (57.14)24.3611
2020's6 (21.43)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Zanet, S1
Morelli, S1
Di Cesare, A1
Bò, S1
Traversa, D1
Lebon, W1
Beugnet, F1
Simonato, G1
Ferroglio, E1
El Saftawy, EA1
El-Dardiry, MA1
Abd-Elaal, AA1
Negm, MSI1
Amin, NM1
Steuer, AE1
Scoggin, K1
Stewart, JC1
Barker, VD1
Adams, AA1
Loynachan, AT1
Nielsen, MK1
Elhenawy, AA1
Elmehankar, MS1
Nabih, N1
Elzoheiry, MA1
Hany, H1
El-Gamal, R1
Aboukamar, WA1
Sousa, MS1
Meneses, GC1
Dam, GJV1
Corstjens, PLAM1
Galvão, RLF1
Pinheiro, MCC1
Martins, AMC1
Daher, EF1
Bezerra, FSM1
Shen, J1
Wang, L1
Peng, M1
Liu, Z1
Zhang, B1
Zhou, T1
Sun, X1
Wu, Z1
Santos, MP1
Gonçalves-Santos, E1
Gonçalves, RV2
Santos, EC1
Campos, CC2
Bastos, DSS1
Marques, MJ2
Souza, RLM2
Novaes, RD2
Wilgus, NC1
Williams, P1
Bolesta, ES1
Chamberland, RR1
Garcia, HH3
Del Brutto, OH1
Stecher, CW1
Fofana, HKM1
Madsen, H1
Wilson, S1
Keita, AD1
Landouré, A1
Traoré, MS1
Vennervald, BJ1
Reimert, CM1
Sacko, M1
Mahanty, S3
Orrego, MA1
Cangalaya, C2
Adrianzen, MP1
Arroyo, G1
Calcina, J1
Gonzalez, AE2
Guerra-Giraldez, C2
Nash, TE3
Toledo, A1
Osorio, R1
Matus, C1
Martinez Lopez, Y1
Ramirez Cruz, N1
Sciutto, E1
Fragoso, G1
Arauz, A1
Carrillo-Mezo, R1
Fleury, A1
Ware, JM1
Coyle, CM1
Dias, MV1
Castro, AP1
Souza-Silva, TG1
Yue, X1
Wei, X1
Zhu, Y1
Han, P1
Li, X1
Wei, Q1
Liu, L1
Yepes, E1
Varela-M, RE1
López-Abán, J1
Rojas-Caraballo, J1
Muro, A1
Mollinedo, F1
Sudsarn, P1
Boonmars, T1
Ruangjirachuporn, W1
Namwat, N1
Loilome, W1
Sriraj, P1
Aukkanimart, R1
Nadchanan, W1
Jiraporn, S1
Zimic, M1
Marzal, M1
Erikstrup, C1
Kallestrup, P1
Zinyama-Gutsire, RB1
Gomo, E1
van Dam, GJ1
Deelder, AM1
Butterworth, AE1
Pedersen, BK1
Ostrowski, SR1
Gerstoft, J1
Ullum, H1
Landeyro, J1
Elguezabal, A1
Gené, M1
García-Fontgivell, J1
Mayayo, E1
Kolosionek, E1
Crosby, A1
Harhay, MO1
Morrell, N1
Butrous, G1
Mutapi, F1
Rujeni, N1
Bourke, C1
Mitchell, K1
Appleby, L1
Nausch, N1
Midzi, N1
Mduluza, T1
Leenstra, T1
Coutinho, HM1
Acosta, LP1
Langdon, GC1
Su, L1
Olveda, RM1
McGarvey, ST1
Kurtis, JD1
Friedman, JF1
Rosin, MP1
Saad el Din Zaki, S1
Ward, AJ1
Anwar, WA1
Bang, OY1
Heo, JH1
Choi, SA1
Kim, DI1
Jung, H1
Hurtado, M1
Medina, MT1
Sanchez, M1
Sotelo, J1
Byram, JE1
Harrison, RA1
von Lichtenberg, F1
Webbe, G1
Sturrock, RF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Childhood Schistosomiasis: a Novel Strategy Extending the Benefits/Reach of Antihelminthic Treatment[NCT02495909]700 participants (Actual)Observational2016-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for praziquantel and Inflammation

ArticleYear
Antiparasitic treatment of neurocysticercosis - The effect of cyst destruction in seizure evolution.
    Epilepsy & behavior : E&B, 2017, Volume: 76

    Topics: Albendazole; Anticestodal Agents; Antiparasitic Agents; Brain; Cysts; Epilepsy; Female; Humans; Infl

2017
Pulmonary vascular disease associated with schistosomiasis.
    Expert review of anti-infective therapy, 2010, Volume: 8, Issue:12

    Topics: Animals; Familial Primary Pulmonary Hypertension; Female; Humans; Hypertension, Portal; Hypertension

2010
Involvement of inflammatory reactions and elevated cell proliferation in the development of bladder cancer in schistosomiasis patients.
    Mutation research, 1994, Mar-01, Volume: 305, Issue:2

    Topics: Cell Division; DNA Damage; Humans; Inflammation; Micronucleus Tests; Praziquantel; Schistosomiasis;

1994

Trials

3 trials available for praziquantel and Inflammation

ArticleYear
Efficacy of fipronil/(S)-methoprene/eprinomectin/praziquantel (Broadline
    Parasites & vectors, 2021, Sep-15, Volume: 14, Issue:1

    Topics: Animals; Antiparasitic Agents; Cat Diseases; Cats; Drug Combinations; Eye; Female; Inflammation; Ive

2021
Schistosomiasis and infection with human immunodeficiency virus 1 in rural Zimbabwe: systemic inflammation during co-infection and after treatment for schistosomiasis.
    The American journal of tropical medicine and hygiene, 2008, Volume: 79, Issue:3

    Topics: Adolescent; Adult; Cohort Studies; Cross-Sectional Studies; Cytokines; Female; HIV Infections; HIV-1

2008
Schistosoma haematobium treatment in 1-5 year old children: safety and efficacy of the antihelminthic drug praziquantel.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:5

    Topics: Administration, Oral; Animals; Anthelmintics; Appetite; Child; Child, Preschool; Feeding and Eating

2011

Other Studies

22 other studies available for praziquantel and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Potentiality of curcumin on ISHAK scoring system and the expressions of BAX, IL-17A, and EGF in the treatment ofSchistosoma mansoni infection using Swiss albino mice.
    Tropical biomedicine, 2022, Mar-01, Volume: 39, Issue:1

    Topics: Animals; Anthelmintics; bcl-2-Associated X Protein; Curcumin; Epidermal Growth Factor; Granuloma; In

2022
Comparison of the host response to larvicidal and nonlarvicidal treatment of naturally acquired cyathostomin infections in horses.
    Parasite immunology, 2022, Volume: 44, Issue:10

    Topics: Animals; Anthelmintics; Feces; Horse Diseases; Horses; Inflammation; Ivermectin; Larva; Macrolides;

2022
Biochanin A in murine
    Journal of helminthology, 2023, Feb-06, Volume: 97

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Fibrosis; Inflammation; Liver; Mice; Oxidative Str

2023
Subclinical signs of podocyte injury associated with Circulating Anodic Antigen (CAA) in Schistosoma mansoni-infected patients in Brazil.
    Revista da Sociedade Brasileira de Medicina Tropical, 2023, Volume: 56

    Topics: Animals; Antigens, Helminth; Brazil; Humans; Inflammation; Podocytes; Praziquantel; Prevalence; Schi

2023
Recombinant Sj16 protein with novel activity alleviates hepatic granulomatous inflammation and fibrosis induced by Schistosoma japonicum associated with M2 macrophages in a mouse model.
    Parasites & vectors, 2019, Sep-23, Volume: 12, Issue:1

    Topics: Animals; Anthelmintics; Disease Models, Animal; Fibrosis; Granuloma; Helminth Proteins; Immunologic

2019
Doxycycline aggravates granulomatous inflammation and lung microstructural remodeling induced by Schistosoma mansoni infection.
    International immunopharmacology, 2021, Volume: 94

    Topics: Airway Remodeling; Animals; Anthelmintics; Cytokines; Disease Models, Animal; Doxycycline; Granuloma

2021
Photo Quiz: A 46-Year-Old Man with a Lung Mass and History of Hemoptysis.
    Journal of clinical microbiology, 2017, Volume: 55, Issue:6

    Topics: Anthelmintics; Anti-Bacterial Agents; Biopsy; Hemoptysis; Humans; Inflammation; Lung; Male; Middle A

2017
Inflammation dynamics after praziquantel treatment of Schistosoma haematobium reflected by urinary eosinophil cationic protein.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2017, 07-01, Volume: 111, Issue:7

    Topics: Adolescent; Adult; Animals; Anthelmintics; Biomarkers; Child; Child, Preschool; Cohort Studies; Eosi

2017
TNF-α blockade suppresses pericystic inflammation following anthelmintic treatment in porcine neurocysticercosis.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:11

    Topics: Animals; Anticestodal Agents; Antiparasitic Agents; Blood-Brain Barrier; Brain; Cytokines; Dexametha

2017
Human Extraparenchymal Neurocysticercosis: The Control of Inflammation Favors the Host…but Also the Parasite.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Adrenal Cortex Hormones; Animals; Anthelmintics; Biomarkers; Brain; Drug Therapy, Combination; Foodb

2018
Etanercept to Control Inflammation in the Treatment of Complicated Neurocysticercosis.
    The American journal of tropical medicine and hygiene, 2019, Volume: 100, Issue:3

    Topics: Adult; Albendazole; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Etanercept; Female; Huma

2019
Doxycycline hyclate: A schistosomicidal agent in vitro with immunomodulatory potential on granulomatous inflammation in vivo.
    International immunopharmacology, 2019, Volume: 70

    Topics: Animals; Antimalarials; Cells, Cultured; Disease Models, Animal; Doxycycline; Granuloma; Humans; Imm

2019
Vesical paragonimiasis diagnosed by histopathology: a case report.
    Urologia internationalis, 2014, Volume: 93, Issue:3

    Topics: Animals; Antiparasitic Agents; Humans; Inflammation; Male; Middle Aged; Paragonimiasis; Paragonimus;

2014
Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:7

    Topics: Animals; Anthelmintics; Cytokines; Gene Expression Regulation; Granuloma; Inflammation; Mice; Phosph

2015
Combination of Praziquantel and Aspirin Minimizes Liver Pathology of Hamster Opisthorchis viverrini Infection Associated Cholangiocarcinoma.
    Pathology oncology research : POR, 2016, Volume: 22, Issue:1

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile Duct Neoplasms; Bile

2016
Inflammation Caused by Praziquantel Treatment Depends on the Location of the Taenia solium Cysticercus in Porcine Neurocysticercosis.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:12

    Topics: Animals; Anthelmintics; Brain; Histocytochemistry; Inflammation; Meninges; Neurocysticercosis; Prazi

2015
Rectal inflammatory polyp in a child: an unusual case of polyparasitism.
    Journal of tropical pediatrics, 2010, Volume: 56, Issue:4

    Topics: Albendazole; Animals; Child; Humans; Inflammation; Male; Polyps; Praziquantel; Rectum; Schistosoma h

2010
Schistosoma japonicum reinfection after praziquantel treatment causes anemia associated with inflammation.
    Infection and immunity, 2006, Volume: 74, Issue:11

    Topics: Adolescent; Adult; Anemia; Anemia, Iron-Deficiency; Animals; Anthelmintics; Child; Cohort Studies; F

2006
Large cerebral infarction during praziquantel therapy in neurocysticercosis.
    Stroke, 1997, Volume: 28, Issue:1

    Topics: Antiplatyhelmintic Agents; Basal Ganglia; Brain Diseases; Carotid Artery, Internal; Cerebral Angiogr

1997
Dexamethasone increases plasma levels of albendazole.
    Journal of neurology, 1990, Volume: 237, Issue:5

    Topics: Adult; Albendazole; Cysticercosis; Dexamethasone; Drug Therapy, Combination; Female; Humans; Inflamm

1990
Pathology resulting from the administration of a live attenuated anti-Schistosoma haematobium vaccine in baboons.
    The American journal of tropical medicine and hygiene, 1989, Volume: 40, Issue:1

    Topics: Animals; Eosinophilia; Eosinophils; Immunization, Secondary; Inflammation; Leukocyte Count; Papio; P

1989