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praziquantel and Enlarged Liver

praziquantel has been researched along with Enlarged Liver in 32 studies

azinox: Russian drug

Research Excerpts

ExcerptRelevanceReference
"Five hundred thirty six Sudanese schoolchildren with Schistosoma mansoni infection were treated at random with either 20 mg or 40 mg/kg praziquantel."9.07Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity seven months after treatment with praziquantel. ( Abdalla, M; Abdel-Rahim, IM; Doehring-Schwerdtfeger, E; Elsheikh, M; Franke, D; Kaiser, C; Kardorff, R; Mohamed-Ali, Q; Schafer, P; Schlake, J, 1991)
"A repeat survey for schistosomiasis japonica was carried out in Sisan community 1 year after chemotherapy with praziquantel was stopped."5.29Changes in prevalence, intensity of infection and morbidity due to Schistosoma japonicum infection in a community following a single treatment with praziquantel. ( Jiang, Q; Liu, Z; ljWu, Z; Wasley, A; Yuan, H; Zhang, S; Zhao, G, 1995)
"The pharmacokinetics and therapeutic efficacy of praziquantel (Distocide; Epico, El-Asher-Men-Ramadan City, Egypt) were studied in 40 patients with schistosomiasis mansoni and various degrees of hepatic dysfunction."5.07Clinical and pharmacokinetic study of praziquantel in Egyptian schistosomiasis patients with and without liver cell failure. ( Abdel-Bary, MA; Abdel-Fatah, SA; el Guiniady, MA; el Touny, MA; Metwally, A, 1994)
"A comparison was made of the long-term impact of different methods of administration of chemotherapy (oxamniquine, 30 mg/kg in divided doses; or praziquantel, 40 mg/kg) on prevalence and intensity of Schistosoma mansoni infection in four areas in Kangundo Location, Machakos District, Kenya."5.07Comparison of different chemotherapy strategies against Schistosoma mansoni in Machakos District, Kenya: effects on human infection and morbidity. ( Butterworth, AE; Fulford, AJ; Kariuki, HC; Koech, D; Mbugua, GG; Ouma, JH; Sturrock, RF, 1991)
"Five hundred thirty six Sudanese schoolchildren with Schistosoma mansoni infection were treated at random with either 20 mg or 40 mg/kg praziquantel."5.07Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity seven months after treatment with praziquantel. ( Abdalla, M; Abdel-Rahim, IM; Doehring-Schwerdtfeger, E; Elsheikh, M; Franke, D; Kaiser, C; Kardorff, R; Mohamed-Ali, Q; Schafer, P; Schlake, J, 1991)
" This 'new' burden, inclusive of co-infections with Schistosoma haematobium and Schistosoma mansoni, is being formally explored as infected children are not presently targeted to receive praziquantel (PZQ) within current preventive chemotherapy campaigns."4.87Closing the praziquantel treatment gap: new steps in epidemiological monitoring and control of schistosomiasis in African infants and preschool-aged children. ( Amin, MA; Betson, M; Fenwick, A; Gabrielli, AF; Garba, A; Green, HK; Kabatereine, NB; Montresor, A; Mutapi, F; Mutumba-Nakalembe, M; Navaratnam, A; Sacko, M; Seto, EY; Sousa-Figueiredo, JC; Stothard, JR; Vaz Nery, S, 2011)
"We evaluated praziquantel for therapy of active Schistosoma mansoni infection in 15 rural Egyptian males with hepatosplenic schistosomiasis."3.67Praziquantel for treatment of schistosomiasis in patients with advanced hepatosplenomegaly. ( Bassily, S; Dunn, M; el-Masry, NA; Farid, Z; Stek, M, 1985)
"Schistomiasis was associated with hepatomegaly (adjusted prevalence ratio [aPR] = 1."1.42Morbidity associated with schistosomiasis before and after treatment in young children in Rusinga Island, western Kenya. ( Davis, SM; Fox, LM; Harris, R; Kareko, EI; Mulama, F; Mwinzi, PM; Ochola, E; Odiere, MR; Rawago, F; Samuels, AM; Wiegand, RE; Won, KY, 2015)
"Hepatosplenomegaly was more marked in schistosome and malaria co-infected mice compared to either infection separately."1.35Plasmodium yoelii: adverse outcome of non-lethal P. yoelii malaria during co-infection with Schistosoma mansoni in BALB/c mouse model. ( Kumar, N; Sangweme, D; Shiff, C, 2009)
"Clinical hepatomegaly (25 vs."1.34Liver morbidity due to Schistosoma mekongi in Cambodia after seven rounds of mass drug administration. ( Cheam, S; Degrémont, A; Hatz, C; Keang, H; Odermatt, P; Odermatt-Biays, S, 2007)
"Praziquantel (40 mg/kg) was given at months 0, 12, 24, and 36 to those showing eggs in the feces with a single 28-mg Kato slide."1.29Impact of repeated community-based selective chemotherapy on morbidity due to schistosomiasis mansoni. ( Engels, D; Gryseels, B; Nkulikyinka, L, 1994)
"A repeat survey for schistosomiasis japonica was carried out in Sisan community 1 year after chemotherapy with praziquantel was stopped."1.29Changes in prevalence, intensity of infection and morbidity due to Schistosoma japonicum infection in a community following a single treatment with praziquantel. ( Jiang, Q; Liu, Z; ljWu, Z; Wasley, A; Yuan, H; Zhang, S; Zhao, G, 1995)
"Forty-six school children with japonicum schistosomiasis living in a village at Napu Valley, Indonesia were treated with praziquantel at a dosage of 70 mg/kg in two divided doses in a day."1.28The effect of praziquantel treatment on liver and spleen size of children with schistosomiasis in Napu Valley, central Sulawesi. ( Campbell, J; Hadidjaja, P; Ismid, IS; Putrali, J; Sudomo, M; Syamsuddin, N, 1990)
"The high frequence of hepatomegaly, and to a lesser extent of splenomegaly, which were shown to be related to schistosome infection, however, have disappeared."1.28Eight years of targeted mass treatment of Schistosoma mansoni infection in Maniema, Zaire. ( de Caluwe, P; Polderman, AM, 1989)
"Hepatomegaly was somewhat more frequent in moderate and heavy infections, but splenomegaly was rare and unrelated to intensity of infection."1.27Morbidity in schistosomiasis japonica in relation to intensity of infection. A study of two rural brigades in Anhui Province, China. ( Cook, JA; Houser, HB; Mott, KE; Peters, PA; Su, DL; Warren, KS; Xu, ZY; Yuan, HC, 1983)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199010 (31.25)18.7374
1990's14 (43.75)18.2507
2000's4 (12.50)29.6817
2010's4 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mueller, A1
Fuss, A1
Ziegler, U1
Kaatano, GM1
Mazigo, HD1
Davis, SM1
Wiegand, RE1
Mulama, F1
Kareko, EI1
Harris, R1
Ochola, E1
Samuels, AM1
Rawago, F1
Mwinzi, PM1
Fox, LM1
Odiere, MR1
Won, KY1
Sangweme, D1
Shiff, C1
Kumar, N1
Juraschek, SP1
Bankova, L1
Falade, O1
Chow, G1
McKenzie, R1
Bhogal, HK1
Stothard, JR1
Sousa-Figueiredo, JC1
Betson, M1
Green, HK1
Seto, EY1
Garba, A1
Sacko, M1
Mutapi, F1
Vaz Nery, S1
Amin, MA1
Mutumba-Nakalembe, M1
Navaratnam, A1
Fenwick, A1
Kabatereine, NB1
Gabrielli, AF1
Montresor, A1
Traore, HA1
Maiga, MY1
Sogodogo, S1
Dembele, M1
Sidibe, TA1
Diallo, D1
Diallo, AN1
Guindo, A1
Pichard, E1
Doumbo, O1
Vennervald, BJ2
Booth, M2
Butterworth, AE2
Kariuki, HC3
Kadzo, H2
Ireri, E2
Amaganga, C2
Kimani, G2
Kenty, L1
Mwatha, J1
Ouma, JH3
Dunne, DW2
Keang, H1
Odermatt, P1
Odermatt-Biays, S1
Cheam, S1
Degrémont, A1
Hatz, C1
Wilson, S1
Mwatha, JK1
Muchiri, E1
Hayashi, M1
Matsuda, H1
Tormis, LC1
Noseñas, JS1
Blas, BL1
Warren, KS1
Su, DL1
Xu, ZY1
Yuan, HC1
Peters, PA3
Cook, JA1
Mott, KE1
Houser, HB1
el Guiniady, MA1
el Touny, MA1
Abdel-Bary, MA1
Abdel-Fatah, SA1
Metwally, A1
Gryseels, B1
Nkulikyinka, L1
Engels, D1
Wiest, PM2
Wu, G1
Zhong, S1
McGarvey, ST1
Yuan, J1
Olveda, RM2
Olds, GR2
Zhao, G1
Jiang, Q1
Wasley, A1
Zhang, S1
ljWu, Z1
Liu, Z1
Yuan, H1
Daniel, BL1
Ramirez, BD1
Aligui, GD1
Acosta, LP1
Fevidal, P1
Tiu, E1
de Veyra, F1
Romulo, R1
Domingo, E1
Pungpak, S1
Viravan, C1
Radomyos, B1
Chalermrut, K1
Yemput, C1
Plooksawasdi, W1
Ho, M1
Harinasuta, T1
Bunnag, D1
el-Karaksy, H1
Hassanein, B1
Okasha, S1
Behairy, B1
Gadallah, I1
Bina, JC1
el-Hawey, AM1
Abou-Taleb, SA1
el-Gammal, HA1
Abdel-Rahman, MM1
Sabry, AA1
Sturrock, RF1
Mbugua, GG1
Fulford, AJ1
Koech, D1
Mohamed-Ali, Q1
Doehring-Schwerdtfeger, E1
Abdel-Rahim, IM1
Schlake, J1
Kardorff, R1
Franke, D1
Kaiser, C1
Elsheikh, M1
Abdalla, M1
Schafer, P1
Homeida, MA1
el Tom, I1
Nash, T1
Bennett, JL1
Hadidjaja, P2
Ismid, IS2
Sudomo, M2
Syamsuddin, N2
Putrali, J2
Campbell, J2
Polderman, AM1
de Caluwe, P1
Stephenson, LS1
Kinoti, SN1
Latham, MC1
Kurz, KM1
Kyobe, J1
Zwingenberger, K1
Harms, G1
Feldmeier, H1
Müller, O1
Steiner, A1
Bienzle, U1
Sukwa, TY1
Bulsara, MK1
Wurapa, FK1
el-Ridi, AM1
el-Gamal, RL1
Sobhy, MM1
el-Naggar, AM1
Mansour, MA1
Mahfouz, S1
Coutinho, A1
Domingues, AL1
Bassily, S1
Farid, Z1
Dunn, M1
el-Masry, NA1
Stek, M1

Reviews

2 reviews available for praziquantel and Enlarged Liver

ArticleYear
Closing the praziquantel treatment gap: new steps in epidemiological monitoring and control of schistosomiasis in African infants and preschool-aged children.
    Parasitology, 2011, Volume: 138, Issue:12

    Topics: Africa; Age Factors; Anemia; Animals; Anthelmintics; Child, Preschool; Coinfection; Feces; Female; H

2011
[Specific treatment as a weapon for controlling schistosomiasis].
    Memorias do Instituto Oswaldo Cruz, 1992, Volume: 87 Suppl 4

    Topics: Adolescent; Brazil; Child; Child, Preschool; Clinical Trials as Topic; Female; Follow-Up Studies; He

1992

Trials

4 trials available for praziquantel and Enlarged Liver

ArticleYear
Clinical and pharmacokinetic study of praziquantel in Egyptian schistosomiasis patients with and without liver cell failure.
    The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:6

    Topics: Absorption; Adolescent; Adult; Bilirubin; Female; Hepatomegaly; Humans; Linear Models; Liver; Liver

1994
Comparison of different chemotherapy strategies against Schistosoma mansoni in Machakos District, Kenya: effects on human infection and morbidity.
    Parasitology, 1991, Volume: 103 Pt 3

    Topics: Adolescent; Age Factors; Child; Cohort Studies; Feces; Follow-Up Studies; Hepatomegaly; Humans; Keny

1991
Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity seven months after treatment with praziquantel.
    The American journal of tropical medicine and hygiene, 1991, Volume: 44, Issue:4

    Topics: Child; Hepatomegaly; Humans; Liver; Liver Cirrhosis; Parasite Egg Count; Praziquantel; Random Alloca

1991
Single dose metrifonate or praziquantel treatment in Kenyan children. I. Effects on Schistosoma haematobium, hookworm, hemoglobin levels, splenomegaly, and hepatomegaly.
    The American journal of tropical medicine and hygiene, 1989, Volume: 41, Issue:4

    Topics: Adolescent; Animals; Child; Cross-Sectional Studies; Female; Hemoglobins; Hepatomegaly; Hookworm Inf

1989

Other Studies

26 other studies available for praziquantel and Enlarged Liver

ArticleYear
Intestinal schistosomiasis of Ijinga Island, north-western Tanzania: prevalence, intensity of infection, hepatosplenic morbidities and their associated factors.
    BMC infectious diseases, 2019, Oct-07, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anthelmintics; Child; Child, Preschool; Cross-S

2019
Morbidity associated with schistosomiasis before and after treatment in young children in Rusinga Island, western Kenya.
    The American journal of tropical medicine and hygiene, 2015, Volume: 92, Issue:5

    Topics: Age Distribution; Animals; Anthelmintics; Child; Child, Preschool; Cohort Studies; Cross-Sectional S

2015
Plasmodium yoelii: adverse outcome of non-lethal P. yoelii malaria during co-infection with Schistosoma mansoni in BALB/c mouse model.
    Experimental parasitology, 2009, Volume: 122, Issue:3

    Topics: Anemia; Animals; Anthelmintics; Disease Models, Animal; Female; Hematocrit; Hepatomegaly; Malaria; M

2009
An uncommon cause of portal hypertension: schistosomiasis.
    The American journal of medicine, 2011, Volume: 124, Issue:2

    Topics: Adult; Animals; Anthelmintics; Antihypertensive Agents; Hepatomegaly; Humans; Hypertension, Portal;

2011
[Importance of hepatic bilharziasis in liver pathologies in the internal medicine department of the National Hospital of Point "G", Bamako-Mali].
    Dakar medical, 1996, Volume: Spec No

    Topics: Adolescent; Adult; Aged; Anthelmintics; Biopsy; Child; Female; Granuloma; Hepatomegaly; Hospital Dep

1996
Regression of hepatosplenomegaly in Kenyan school-aged children after praziquantel treatment and three years of greatly reduced exposure to Schistosoma mansoni.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2005, Volume: 99, Issue:2

    Topics: Adolescent; Age Distribution; Anthelmintics; Child; Cohort Studies; Female; Hepatomegaly; Humans; Ke

2005
Liver morbidity due to Schistosoma mekongi in Cambodia after seven rounds of mass drug administration.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:8

    Topics: Adolescent; Adult; Aged; Animals; Cambodia; Cross-Sectional Studies; Female; Hepatomegaly; Humans; L

2007
Hepatosplenomegaly in Kenyan schoolchildren: exacerbation by concurrent chronic exposure to malaria and Schistosoma mansoni infection.
    Tropical medicine & international health : TM & IH, 2007, Volume: 12, Issue:12

    Topics: Adolescent; Animals; Anthelmintics; Child; Child, Preschool; Cross-Sectional Studies; Female; Hepato

2007
Clinical study on hepatosplenomegalic schistosomiasis japonica on Leyte Island: follow-up study 4 years after treatment with praziquantel.
    The Southeast Asian journal of tropical medicine and public health, 1984, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Evaluation; Female; Follow-Up Studies; Hepato

1984
Morbidity in schistosomiasis japonica in relation to intensity of infection. A study of two rural brigades in Anhui Province, China.
    The New England journal of medicine, 1983, Dec-22, Volume: 309, Issue:25

    Topics: Adolescent; Adult; Child; Child, Preschool; China; Feces; Female; Hepatomegaly; Humans; Male; Medica

1983
Impact of repeated community-based selective chemotherapy on morbidity due to schistosomiasis mansoni.
    The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:5

    Topics: Abdominal Pain; Adolescent; Adult; Age Factors; Burundi; Child; Child, Preschool; Cluster Analysis;

1994
Impact of annual screening and chemotherapy with praziquantel on schistosomiasis japonica on Jishan Island, People's Republic of China.
    The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:2

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; China; Cohort Studies; Feces; Female; Hepat

1994
Changes in prevalence, intensity of infection and morbidity due to Schistosoma japonicum infection in a community following a single treatment with praziquantel.
    Tropical and geographical medicine, 1995, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Age Distribution; Antiplatyhelmintic Agents; Child; Child, Preschool; China; Foll

1995
Schistosomiasis japonica in the Philippines: the long-term impact of population-based chemotherapy on infection, transmission, and morbidity.
    The Journal of infectious diseases, 1996, Volume: 174, Issue:1

    Topics: Adolescent; Adult; Age Distribution; Antiplatyhelmintic Agents; Child; Child, Preschool; Female; Hep

1996
Opisthorchis viverrini infection in Thailand: studies on the morbidity of the infection and resolution following praziquantel treatment.
    The American journal of tropical medicine and hygiene, 1997, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Antiplatyhelmintic Agents; Biliary Tract; Child; Child, Preschool; Feces; Female;

1997
Human fascioliasis in Egyptian children: successful treatment with triclabendazole.
    Journal of tropical pediatrics, 1999, Volume: 45, Issue:3

    Topics: Anthelmintics; Benzimidazoles; Child; Egypt; Eosinophilia; Fascioliasis; Female; Fever; Follow-Up St

1999
Profile of portal hypertension in hepatosplenic schistosomiasis.
    Journal of the Egyptian Society of Parasitology, 1992, Volume: 22, Issue:2

    Topics: Feces; Hepatomegaly; Humans; Hypertension, Portal; Parasite Egg Count; Praziquantel; Schistosomiasis

1992
Association of the therapeutic activity of praziquantel with the reversal of Symmers' fibrosis induced by Schistosoma mansoni.
    The American journal of tropical medicine and hygiene, 1991, Volume: 45, Issue:3

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Female; Hepatomegaly; Humans; Liver Cirrhos

1991
The effect of praziquantel treatment on liver and spleen size of children with schistosomiasis in Napu Valley, central Sulawesi.
    The Southeast Asian journal of tropical medicine and public health, 1990, Volume: 21, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Female; Hepatomegaly; Humans; Indonesia; Male; Praziquantel; Sc

1990
Eight years of targeted mass treatment of Schistosoma mansoni infection in Maniema, Zaire.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1989, Volume: 40, Issue:2

    Topics: Animals; Democratic Republic of the Congo; Hepatomegaly; Humans; Praziquantel; Schistosomiasis manso

1989
Liver involvement in human schistosomiasis mansoni. Regression of immunological and biochemical disease markers after specific treatment.
    Acta tropica, 1988, Volume: 45, Issue:3

    Topics: Adolescent; Adult; Animals; Antibodies, Helminth; beta 2-Microglobulin; Biopterins; Child; Child, Pr

1988
Reduction in prevalence, intensity of infection and morbidity due to Schistosoma mansoni infection in a community following treatment with praziquantel.
    The Journal of tropical medicine and hygiene, 1987, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; Female; Hepatomegaly; Humans; Infant; Male; Middle Aged;

1987
Zinc and praziquantel on the pathogenesis of hepatosplenomegaly in experimental mansoniasis.
    Journal of the Egyptian Society of Parasitology, 1988, Volume: 18, Issue:2

    Topics: Animals; Hepatomegaly; Mice; Praziquantel; Schistosomiasis mansoni; Splenomegaly; Zinc

1988
Specific treatment of advanced schistosomiasis liver disease in man: favourable results.
    Memorias do Instituto Oswaldo Cruz, 1987, Volume: 82 Suppl 4

    Topics: Adolescent; Adult; Aged; Child; Drug Evaluation; Female; Hepatitis, Chronic; Hepatomegaly; Humans; L

1987
Praziquantel for treatment of schistosomiasis in patients with advanced hepatosplenomegaly.
    Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:6

    Topics: Adolescent; Adult; Child; Feces; Hepatitis B Surface Antigens; Hepatomegaly; Humans; Male; Middle Ag

1985
The impact of schistosomiasis mass treatment on hepato-splenomegaly in Napu Valley, Central Sulawesi, Indonesia.
    The Southeast Asian journal of tropical medicine and public health, 1985, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Child; Child, Preschool; Female; Hepatomegaly; Humans; Indonesia; Infant; Infant,

1985