Compounds > praziquantel
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praziquantel and Disease Models, Animal

praziquantel has been researched along with Disease Models, Animal in 130 studies

azinox: Russian drug

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as preventive chemotherapy as part of national helminth control strategies."9.05Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models. ( Mutapi, F; Zdesenko, G, 2020)
"Schistosomiasis is a widely distributed parasitic disease and one of the most important neglected tropical diseases globally, for which Praziquantel® (PZQ) is the only available treatment."8.12The Effect of Different Formulations of Praziquantel in Reducing Worms in the Prepatent Period of Schistosomiasis in Murine Models. ( da Silva, CH; de Moraes Neto, AHA; Leonardi, D; Mello Silva, CC; Paulino, ÉT; Real, DA; Ribeiro de Lima, M; Salomon, CJ; Viçosa, AL, 2022)
" The present study evaluated the effect of oral administration of five days celecoxib regimen (20 mg/kg/day) against different developmental stages of Schistosoma mansoni infection."8.02Effect of celecoxib against different developmental stages of experimental Schistosoma mansoni infection. ( Abou-El-Naga, IF; El-Temsahy, MM; Ibrahim, EI; Makled, S; Mogahed, NMFH; Sheta, E, 2021)
"These results provide the first preclinical evidence that praziquantel may effectively treat psoriasis, and suggest that praziquantel alleviates symptoms in mice by inhibiting STAT3 phosphorylation, thereby suppressing Th17 immune responses."8.02Repurposing the anthelmintic praziquantel to treat psoriasis. ( Bae, EJ; Hao, L; Mao, Y; Park, BH; Park, J, 2021)
"In view of the potential immunosuppressive and regenerative properties of mesenchymal stem cells (MSC), we investigated whether transplantation of adipose tissue-derived stem cells (ASC) could be used to control the granulomatous reaction in the liver of mice infected with Schistosoma mansoni after Praziquantel (PZQ) treatment."7.96Liver damage in schistosomiasis is reduced by adipose tissue-derived stem cell therapy after praziquantel treatment. ( Alves, ÉAR; Bicalho, KA; Birbrair, A; Bozzi, A; Chaves, AT; Corrêa-Oliveira, R; de Goes, AM; Eller, DE; Ferraz, LCN; Gomes, TR; Miranda, VHS; Pascoal Xavier, MA; Silva, CEC, 2020)
"Epidemiological studies in China have revealed that Schistosoma japonicum infection is inversely correlated with metabolic syndrome, even after repeated chemotherapy with praziquantel (PZQ)."7.85Praziquantel treatment after Schistosoma japonicum infection maintains hepatic insulin sensitivity and improves glucose metabolism in mice. ( Chen, L; Hou, M; Ji, M; Liu, R; Luo, X; Song, J; Xu, Z; Yang, B; Zhang, F; Zhang, W; Zhu, Y, 2017)
"A dual drug repurposing/nanotechnological approach was used to develop an alternative oral treatment for schistosomiasis mansoni using miltefosine (MFS), an anticancer alkylphosphocholine, and lipid nanocapsules (LNCs) as oral nanovectors."7.83Miltefosine lipid nanocapsules: Intersection of drug repurposing and nanotechnology for single dose oral treatment of pre-patent schistosomiasis mansoni. ( Eissa, MM; El-Azzouni, MZ; El-Khordagui, LK; El-Moslemany, RM; Ramadan, AA, 2016)
"Porcine Taenia solium cysticercosis, recognized as a model of the human disease, was used to analyze the effect of the anthelminthic drug praziquantel on hosts and parasites."7.68Praziquantel treatment of porcine brain and muscle Taenia solium cysticercosis. 1. Radiological, physiological and histopathological studies. ( Cohen, S; Collado, M; Correa, D; Fernandez, B; Flisser, A; Gonzalez, D; Madrazo, I; Rodriguez-Carbajal, J; Rodriguez-del-Rosal, E; Shkurovich, M, 1990)
" Significant improvement in hepatic oxidative stress levels, serum albumin and total protein in response to GABA treatment alone or combined with PZQ."5.72Schistosomicidal and hepatoprotective activity of gamma-aminobutyric acid (GABA) alone or combined with praziquantel against Schistosoma mansoni infection in murine model. ( Fahmy, AM; Hegab, A; Tm, D; William, S, 2022)
"Praziquantel treatment of infected mice fed with a standard diet (IN-PZQ) resulted in a significant reduction of worm and egg burdens and a normalization of iron and calcium levels."5.72Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection. ( Abou-Bacar, A; Boukeng Jatsa, H; Brunet, J; Cannet, C; Gipwe Feussom, N; Greigert, V; Kadji Fassi, JB; Kamgang, R; Kamtchouing, P; Kenfack, CM; Membe Femoe, U; Pfaff, AW; Tchuem Tchuenté, LA; Tienga Nkondo, E, 2022)
"Neurocysticercosis is the most common parasitic infection of the nervous system and currently represents a serious public health issue in many regions of Latin America, Asia, and Africa."5.48In vivo treatment of experimental neurocysticercosis with praziquantel nanosuspensions-a metabolic approach. ( Arrua, EC; Lima, NF; Salomon, CJ; Silva, LD; Vinaud, MC, 2018)
"The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms."5.46Radiological evolution of porcine neurocysticercosis after combined antiparasitic treatment with praziquantel and albendazole. ( Arroyo, G; Bustos, JA; Calcina, J; Cangalaya, C; Chacaltana, J; García, HH; Gonzalez, AE; Guerra-Giraldez, C; Mahanty, S; Mamani, J; Nash, TE; Suarez, D; Vargas-Calla, A, 2017)
"Pentoxifylline (PTX) was proved to exert both anti-inflammatory and anti-fibrotic effects, and was used therapeutically in this experimental model to investigate its role alone or with praziquantel (PZQ) in Schistosoma mansoni-infected mice, and to explore its impact on the tissue expression of transforming growth factor-beta1 (TGF-beta1)."5.34Pharmacodynamics of pentoxifylline and/or praziquantel in murine schistosomiasis mansoni. ( El-Lakkany, N; Nosseir, M, 2007)
" Pharmacokinetic studies in dogs confirmed that SRP was absorbed more slowly than PZQ."5.32Sustained-release praziquantel tablet: pharmacokinetics and the treatment of clonorchiasis in beagle dogs. ( Choi, MH; Chung, BS; Hong, ST; Kho, WG; Lee, M; Lee, SH; Lee, SJ; Li, S; Seo, M, 2003)
"The present study using a murine model heavily infected with Schistosoma japonicum aimed to elucidate the pathogenesis of adverse effects of praziquantel treatment of schistosome-infected subjects."5.31Adverse effects of praziquantel treatment of Schistosoma japonicum infection: involvement of host anaphylactic reactions induced by parasite antigen release. ( Matsumoto, J, 2002)
"Treatment with praziquantel of individuals from the area residing temporarily in an urban region with no transmission, and re-treatment after 3 weeks of non-cured individuals within the area resulted in normal cure rates (78-88%)."5.31Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence. ( De Vlas, SJ; Diop, M; Engels, D; Faye, D; Gryseels, B; Guissé, F; Ly, A; Mbaye, A; Polman, K; Stelma, FF; Tchuem-Tchuenté, LA; Van Lieshout, L, 2001)
"Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as preventive chemotherapy as part of national helminth control strategies."5.05Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models. ( Mutapi, F; Zdesenko, G, 2020)
"Schistosomiasis is a widely distributed parasitic disease and one of the most important neglected tropical diseases globally, for which Praziquantel® (PZQ) is the only available treatment."4.12The Effect of Different Formulations of Praziquantel in Reducing Worms in the Prepatent Period of Schistosomiasis in Murine Models. ( da Silva, CH; de Moraes Neto, AHA; Leonardi, D; Mello Silva, CC; Paulino, ÉT; Real, DA; Ribeiro de Lima, M; Salomon, CJ; Viçosa, AL, 2022)
" The present study evaluated the effect of oral administration of five days celecoxib regimen (20 mg/kg/day) against different developmental stages of Schistosoma mansoni infection."4.02Effect of celecoxib against different developmental stages of experimental Schistosoma mansoni infection. ( Abou-El-Naga, IF; El-Temsahy, MM; Ibrahim, EI; Makled, S; Mogahed, NMFH; Sheta, E, 2021)
"These results provide the first preclinical evidence that praziquantel may effectively treat psoriasis, and suggest that praziquantel alleviates symptoms in mice by inhibiting STAT3 phosphorylation, thereby suppressing Th17 immune responses."4.02Repurposing the anthelmintic praziquantel to treat psoriasis. ( Bae, EJ; Hao, L; Mao, Y; Park, BH; Park, J, 2021)
"In view of the potential immunosuppressive and regenerative properties of mesenchymal stem cells (MSC), we investigated whether transplantation of adipose tissue-derived stem cells (ASC) could be used to control the granulomatous reaction in the liver of mice infected with Schistosoma mansoni after Praziquantel (PZQ) treatment."3.96Liver damage in schistosomiasis is reduced by adipose tissue-derived stem cell therapy after praziquantel treatment. ( Alves, ÉAR; Bicalho, KA; Birbrair, A; Bozzi, A; Chaves, AT; Corrêa-Oliveira, R; de Goes, AM; Eller, DE; Ferraz, LCN; Gomes, TR; Miranda, VHS; Pascoal Xavier, MA; Silva, CEC, 2020)
"Epidemiological studies in China have revealed that Schistosoma japonicum infection is inversely correlated with metabolic syndrome, even after repeated chemotherapy with praziquantel (PZQ)."3.85Praziquantel treatment after Schistosoma japonicum infection maintains hepatic insulin sensitivity and improves glucose metabolism in mice. ( Chen, L; Hou, M; Ji, M; Liu, R; Luo, X; Song, J; Xu, Z; Yang, B; Zhang, F; Zhang, W; Zhu, Y, 2017)
"A dual drug repurposing/nanotechnological approach was used to develop an alternative oral treatment for schistosomiasis mansoni using miltefosine (MFS), an anticancer alkylphosphocholine, and lipid nanocapsules (LNCs) as oral nanovectors."3.83Miltefosine lipid nanocapsules: Intersection of drug repurposing and nanotechnology for single dose oral treatment of pre-patent schistosomiasis mansoni. ( Eissa, MM; El-Azzouni, MZ; El-Khordagui, LK; El-Moslemany, RM; Ramadan, AA, 2016)
" Praziquantel (PZQ) is the drug of choice for the treatment of opisthorchiasis, but the effects of this drug on O."3.81The first comprehensive study of praziquantel effects in vivo and in vitro on European liver fluke Opisthorchis felineus (Trematoda). ( Katokhin, AV; Mordvinov, VA; Pakharukova, MY; Pirozhkova, DS; Shilov, AG, 2015)
"Praziquantel is currently the only drug of choice for the treatment of human Schistosoma japonicum infections, and praziquantel-based chemotherapy has been proved to be generally effective to control the morbidity and reduce the prevalence and intensity of S."3.80Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum. ( Dai, JR; Ji, Y; Li, HJ; Li, TY; Liang, YS; Qian, YL; Qu, GL; Wang, W, 2014)
"Currently, schistosomiasis mansoni is treated clinically with praziquantel (PZQ)."3.79Liposomal-praziquantel: efficacy against Schistosoma mansoni in a preclinical assay. ( Allegretti, SM; de Souza, AL; Frezza, TF; Gremião, MP; Magalhães, LA; Zanotti-Magalhães, EM, 2013)
"The present study evaluated the use of 3 types of Cysteine Protease Inhibitors (CPIs) with praziquantel (PZQ) as chemotherapy against schistosomiasis mansoni in mice."3.79Overview on cysteine protease inhibitors as chemotherapy for Schistosomiasis mansoni in mice and also its effect on the parasitological and immunological profile. ( El Amir, AM; Farid, A; Helmy, A; Malek, AA; Rabie, I, 2013)
"To explore the value of B-ultrasound on the evaluation of the effects of traditional Chinese medicine compound of Radix astragali, Salvia miltiorrhiza and Angelica sinensis, and TCM + praziquantel on liver fibrosis in rabbits with schistosomiasis."3.79Effect of Chinese herbal compound on liver fibrosis in rabbits with schistosomiasis by B-ultrasound. ( Liang, XL; Yuan, JY, 2013)
"Opisthorchiasis, caused by the liver fluke Opisthorchis viverrini, a food-borne trematode, is an important public health problem; however, only a single drug, praziquantel is available."3.79Activity of tribendimidine and praziquantel combination therapy against the liver fluke Opisthorchis viverrini in vitro and in vivo. ( Adelfio, R; Keiser, J; Odermatt, P; Tesana, S; Vargas, M, 2013)
" Treatment of opisthorchiasis patients with praziquantel, an anti- trematode drug was shown to reduce inflammation-mediated tissue damage and carcinogenesis."3.78Oxidative and nitrative DNA damage: key events in opisthorchiasis-induced carcinogenesis. ( Bartsch, H; Pinlaor, S; Yongvanit, P, 2012)
"To evaluate the effect of rosiglitazone in a murine model of liver fibrosis induced by Schistosoma japonicum infection."3.74Rosiglitazone prevents murine hepatic fibrosis induced by Schistosoma japonicum. ( Chen, H; He, YW; Liu, WQ; Zhang, JH, 2008)
"Porcine Taenia solium cysticercosis, recognized as a model of the human disease, was used to analyze the effect of the anthelminthic drug praziquantel on hosts and parasites."3.68Praziquantel treatment of porcine brain and muscle Taenia solium cysticercosis. 1. Radiological, physiological and histopathological studies. ( Cohen, S; Collado, M; Correa, D; Fernandez, B; Flisser, A; Gonzalez, D; Madrazo, I; Rodriguez-Carbajal, J; Rodriguez-del-Rosal, E; Shkurovich, M, 1990)
" Treatments were performed at the minimum therapeutic dosage 5 days after the experimental infection."2.77Treatment of third-stage larvae of Toxocara cati with milbemycin oxime plus praziquantel tablets and emodepside plus praziquantel spot-on formulation in experimentally infected cats. ( Böhm, C; Schaper, R; Schnieder, T; Wolken, S, 2012)
"Valuable information on human schistosomiasis japonica has been provided using primates and experimental rodent hosts."2.41Schistosoma japonicum infection in the pig as a model for human schistosomiasis japonica. ( Bogh, HO; Christensen, NO; Johansen, MV; Nansen, P, 2000)
" Significant improvement in hepatic oxidative stress levels, serum albumin and total protein in response to GABA treatment alone or combined with PZQ."1.72Schistosomicidal and hepatoprotective activity of gamma-aminobutyric acid (GABA) alone or combined with praziquantel against Schistosoma mansoni infection in murine model. ( Fahmy, AM; Hegab, A; Tm, D; William, S, 2022)
"Praziquantel treatment of infected mice fed with a standard diet (IN-PZQ) resulted in a significant reduction of worm and egg burdens and a normalization of iron and calcium levels."1.72Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection. ( Abou-Bacar, A; Boukeng Jatsa, H; Brunet, J; Cannet, C; Gipwe Feussom, N; Greigert, V; Kadji Fassi, JB; Kamgang, R; Kamtchouing, P; Kenfack, CM; Membe Femoe, U; Pfaff, AW; Tchuem Tchuenté, LA; Tienga Nkondo, E, 2022)
"Praziquantel treatment damages the outermost surface of the parasite, the tegument, liberating surface antigens from dying worms that invoke a robust immune response which in some subjects results in immunologic resistance to reinfection."1.62Immunomics-Guided Antigen Discovery for Praziquantel-Induced Vaccination in Urogenital Human Schistosomiasis. ( Becker, L; Felgner, PL; Greco, B; Jasinskas, A; Loukas, A; Mduluza, T; Mutapi, F; Nakajima, R; Oeuvray, C; Pearson, MS; Sotillo, J; Tedla, BA, 2021)
"Praziquantel has proven to be effective against this parasitic disease, though there are increasing concerns regarding tolerance/resistance that calls for new drugs."1.51In vitro schistosomicidal activity of tamoxifen and its effectiveness in a murine model of schistosomiasis at a single dose. ( Allegretti, SM; Corrêa, SAP; Mendes, T; Miguel, DC; Oliveira, RN; Vieira, KM, 2019)
"PZQ exhibited a strong efficacy against liver fibrosis by inhibiting activation of HSCs via Smad7 up-regulation, suggesting potential broad utility in treatment of diseases characterized by liver fibrosis."1.51Praziquantel ameliorates CCl ( Kong, D; Liu, J; Liu, X; Lu, Z; Qiu, J; Wang, Y; Xie, Y; Zhang, R; Zhou, C, 2019)
"Neurocysticercosis is the most common parasitic infection of the nervous system and currently represents a serious public health issue in many regions of Latin America, Asia, and Africa."1.48In vivo treatment of experimental neurocysticercosis with praziquantel nanosuspensions-a metabolic approach. ( Arrua, EC; Lima, NF; Salomon, CJ; Silva, LD; Vinaud, MC, 2018)
"Opisthorchiasis is a serious human and fish-eating animal's disease affecting bile ducts and the gall bladder."1.48Effects of miconazole/clotrimazole and praziquantel combinations against the liver fluke Opisthorchis felineus in vivo and in vitro. ( Mordvinov, VA; Pakharukov, YV; Pakharukova, MY, 2018)
"Simvastatin has an additional pleiotropic effect halting inflammation and decreasing fibrosis due to increasing IL-10 leading to a hepatoprotective effect."1.46Simvastatin exerts antifibrotic effect and potentiates the antischistosomal effects of praziquantel in a murine model: Role of IL10. ( Aboulfotouh, N; Aladeeb, NM; Elkaref, A; Elmasry, A, 2017)
" Dose-response studies with racemic PZQ with or without addition of an irreversible pan-cytochrome P450 (CYP) inhibitor, 1-aminobenzotriazole (ABT), were performed."1.46Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model. ( Abla, N; Haas, H; Keiser, J; Reimers, N; Spangenberg, T; Vargas, M, 2017)
"The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms."1.46Radiological evolution of porcine neurocysticercosis after combined antiparasitic treatment with praziquantel and albendazole. ( Arroyo, G; Bustos, JA; Calcina, J; Cangalaya, C; Chacaltana, J; García, HH; Gonzalez, AE; Guerra-Giraldez, C; Mahanty, S; Mamani, J; Nash, TE; Suarez, D; Vargas-Calla, A, 2017)
"Liver fibrosis was reduced significantly evidenced by reduced hydroxyproline levels [P<0."1.46Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis. ( Ashour, RH; Elhenawy, AA; Megahed, N; Nabih, N; Shalaby, NM, 2017)
" In the current work, the therapeutic efficacy of different limonin dosing protocols was evaluated in experimentally infected mice harboring Schistosoma mansoni (Egyptian strain) juvenile or adult stages."1.43Dose-response relationship in Schistosoma mansoni juvenile and adult stages following limonin treatment in experimentally infected mice. ( Abdallah, KF; Abou-Ouf, EA; Aly, NS; El-Kholy, AA; Eraky, MA; Hamdan, DI; Hammam, OA; Kishik, SM; Moharam, AF; Rashed, GA, 2016)
"Taenia solium cysticercosis is a common parasitic infection of humans and pigs."1.42Successful Antiparasitic Treatment for Cysticercosis is Associated with a Fast and Marked Reduction of Circulating Antigen Levels in a Naturally Infected Pig Model. ( Bustos, JA; Castillo, Y; Dorny, P; Gabriël, S; Garcia, HH; Gilman, RH; Gonzalez, AE; Praet, N; Rodriguez, S; Zimic, M, 2015)
" japonicum, the subsequent effect of an IC50 dosage of praziquantel was exacerbated, reducing motility from 47% to 27% in female worms and from 61% to 23% in males."1.39Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII. ( Brindley, PJ; Gobert, GN; Hu, W; McManus, DP; Smout, MJ; You, H, 2013)
"Its effect on the extent of liver fibrosis, through estimation of hepatic hydroxyproline and hepatic collagen content in liver hydrolysates, was also evaluated."1.38Tranilast ameliorates impaired hepatic functions in Schistosoma mansoni-infected mice. ( Ammar, EM; Elkashef, WF; Gameil, NM; Said, E; Said, SA, 2012)
" Taken together, these findings suggest that long term administration of ASU may result in a mild course of murine schistosomiasis and may be a promising complementary treatment to PZQ."1.38Evaluation of avocado/soybean unsaponifiable alone or concurrently with praziquantel in murine schistosomiasis. ( Soliman, MF, 2012)
"Echinostomiasis is a food-borne intestinal, snail-mediated parasitosis caused principally by ingestion of snails infected with digenean trematodes of the Echinostoma genus."1.38Effect of praziquantel on adult Echinostoma paraensei worms in experimentally infected mice. ( Costa-Silva, M; Ferraz, J; Garcia, J; Lanfredi, R; Maldonado, A; Santana, A; Souza, J; Torres, E, 2012)
"The purpose of the study is to explore the efficacy of mefloquine administered orally at single, multiple doses, or in combination with artesuante, artemether, or praziquantel in mouse--Schistosoma japonicum model."1.37Effect of mefloquine administered orally at single, multiple, or combined with artemether, artesunate, or praziquantel in treatment of mice infected with Schistosoma japonicum. ( Jiao, PY; Mei, JY; Xiao, SH, 2011)
"Hepatosplenomegaly was more marked in schistosome and malaria co-infected mice compared to either infection separately."1.35Plasmodium yoelii: adverse outcome of non-lethal P. yoelii malaria during co-infection with Schistosoma mansoni in BALB/c mouse model. ( Kumar, N; Sangweme, D; Shiff, C, 2009)
"Pentoxifylline (PTX) was proved to exert both anti-inflammatory and anti-fibrotic effects, and was used therapeutically in this experimental model to investigate its role alone or with praziquantel (PZQ) in Schistosoma mansoni-infected mice, and to explore its impact on the tissue expression of transforming growth factor-beta1 (TGF-beta1)."1.34Pharmacodynamics of pentoxifylline and/or praziquantel in murine schistosomiasis mansoni. ( El-Lakkany, N; Nosseir, M, 2007)
" Pharmacokinetic studies in dogs confirmed that SRP was absorbed more slowly than PZQ."1.32Sustained-release praziquantel tablet: pharmacokinetics and the treatment of clonorchiasis in beagle dogs. ( Choi, MH; Chung, BS; Hong, ST; Kho, WG; Lee, M; Lee, SH; Lee, SJ; Li, S; Seo, M, 2003)
"Developed hydatid cysts were counted, weighed and processed for observation by transmission electron microscopy."1.31Combined praziquantel and albendazole chemoprophylaxis in experimental hydatidosis. ( Casado, N; Moreno, MJ; Rodríguez-Caabeiro, F; Urrea-París, MA, 2001)
"Treatment with praziquantel of individuals from the area residing temporarily in an urban region with no transmission, and re-treatment after 3 weeks of non-cured individuals within the area resulted in normal cure rates (78-88%)."1.31Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence. ( De Vlas, SJ; Diop, M; Engels, D; Faye, D; Gryseels, B; Guissé, F; Ly, A; Mbaye, A; Polman, K; Stelma, FF; Tchuem-Tchuenté, LA; Van Lieshout, L, 2001)
"The present study using a murine model heavily infected with Schistosoma japonicum aimed to elucidate the pathogenesis of adverse effects of praziquantel treatment of schistosome-infected subjects."1.31Adverse effects of praziquantel treatment of Schistosoma japonicum infection: involvement of host anaphylactic reactions induced by parasite antigen release. ( Matsumoto, J, 2002)
"Albendazole was the most effective agent in reducing cyst growth and was, when compared with other regimes significantly more effective than mebendazole (p less than 0."1.28Comparison of albendazole, mebendazole and praziquantel chemotherapy of Echinococcus multilocularis in a gerbil model. ( Morris, DL; Reffin, D; Richards, KS; Taylor, DH, 1989)
"Praziquantel was the most effective drug; a dose of 100 mg/kg given orally for 5 days resulted in a 95% reduction in worm burdens."1.28Experimental chemotherapy of Schistosoma curassoni in mice. ( Hilderson, H; Rollinson, D; Southgate, VR; Vercruysse, J, 1989)

Research

Studies (130)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.31)18.7374
1990's10 (7.69)18.2507
2000's27 (20.77)29.6817
2010's69 (53.08)24.3611
2020's21 (16.15)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Amer, EI2
El-Azzouni, MZ4
El-Bannan, RT1
Shalaby, TI1
El-Achy, SN1
Gomaa, MM1
Membe Femoe, U2
Boukeng Jatsa, H2
Greigert, V2
Brunet, J2
Cannet, C2
Kenfack, MC1
Gipwe Feussom, N2
Kadji Fassi, JB2
Tienga Nkondo, E2
Abou-Bacar, A2
Pfaff, AW2
Dimo, T1
Kamtchouing, P2
Tchuem Tchuenté, LA2
Fahmy, AM1
William, S2
Hegab, A1
Tm, D1
Paulino, ÉT1
Ribeiro de Lima, M1
Viçosa, AL1
da Silva, CH1
Salomon, CJ2
Real, DA1
Leonardi, D1
Mello Silva, CC1
de Moraes Neto, AHA1
Kenfack, CM1
Kamgang, R1
Adekiya, TA1
Kumar, P1
Kondiah, PPD1
Ubanako, P1
Choonara, YE1
Hamdan, ZK1
Soliman, MI1
Taha, HA1
Khalil, MMH1
Nigm, AH1
Liu, J1
Kong, D1
Qiu, J1
Xie, Y1
Lu, Z1
Zhou, C1
Liu, X1
Zhang, R1
Wang, Y2
Shen, J1
Wang, L3
Peng, M1
Liu, Z1
Zhang, B1
Zhou, T1
Sun, X1
Wu, Z2
Tawfeek, GM1
Baki, MHA1
Ibrahim, AN1
Mostafa, MAH1
Fathy, MM1
Diab, MSEDM1
Miranda, VHS1
Gomes, TR1
Eller, DE1
Ferraz, LCN1
Chaves, AT1
Bicalho, KA1
Silva, CEC1
Birbrair, A1
Pascoal Xavier, MA1
de Goes, AM1
Corrêa-Oliveira, R1
Alves, ÉAR1
Bozzi, A1
Eissa, MM3
El-Khordagui, LK3
Abdel Bary, A2
El-Moslemany, RM3
Abdel Salam, SA2
Zdesenko, G1
Mutapi, F2
Mokbel, KEM1
Baiuomy, IR1
Sabry, AEA1
Mohammed, MM1
El-Dardiry, MA1
Pereira, VRD1
da Silveira, LS1
Mengarda, AC2
Alves Júnior, IJ1
da Silva, OOZ1
Miguel, FB1
Silva, MP1
Almeida, ADC2
Torres, DDS1
Pinto, PF2
Coimbra, ES2
de Moraes, J3
Couri, MRC1
da Silva Filho, AA2
Queiroz, LS1
Ferreira, EA1
Denadai, ÂML1
Santos, MP1
Gonçalves-Santos, E1
Gonçalves, RV2
Santos, EC1
Campos, CC2
Bastos, DSS1
Marques, MJ2
Souza, RLM2
Novaes, RD2
Abou-El-Naga, IF1
El-Temsahy, MM1
Mogahed, NMFH1
Sheta, E1
Makled, S1
Ibrahim, EI1
Pearson, MS2
Tedla, BA2
Becker, L2
Nakajima, R1
Jasinskas, A1
Mduluza, T1
Oeuvray, C1
Greco, B1
Sotillo, J1
Felgner, PL1
Loukas, A3
Gasparotto, J1
Senger, MR1
Telles de Sá Moreira, E1
Brum, PO1
Carazza Kessler, FG1
Peixoto, DO1
Panzenhagen, AC1
Ong, LK1
Campos Soares, M1
Reis, PA1
Schirato, GV2
Góes Valente, WC1
Araújo Montoya, BO1
Silva, FP1
Fonseca Moreira, JC1
Dal-Pizzol, F1
Castro-Faria-Neto, HC1
Gelain, DP1
Abu Almaaty, AH1
Rashed, HAE1
Soliman, MFM1
Fayad, E1
Althobaiti, F1
El-Shenawy, NS1
Hao, L1
Mao, Y1
Park, J1
Bae, EJ1
Park, BH1
Elhenawy, AA1
Ashour, RH1
Nabih, N1
Shalaby, NM1
Megahed, N1
Okombo, J1
Singh, K1
Mayoka, G1
Ndubi, F1
Barnard, L1
Njogu, PM1
Njoroge, M1
Gibhard, L1
Brunschwig, C1
Vargas, M5
Keiser, J7
Egan, TJ1
Chibale, K1
Cangalaya, C1
Bustos, JA2
Calcina, J1
Vargas-Calla, A1
Mamani, J1
Suarez, D1
Arroyo, G1
Gonzalez, AE2
Chacaltana, J1
Guerra-Giraldez, C1
Mahanty, S1
Nash, TE1
García, HH2
Sanchez, MC1
Krasnec, KV1
Parra, AS1
von Cabanlong, C1
Gobert, GN3
Umylny, B1
Cupit, PM1
Cunningham, C1
Abla, N1
Reimers, N1
Haas, H1
Spangenberg, T1
Luo, X1
Zhu, Y1
Liu, R1
Song, J1
Zhang, F1
Zhang, W3
Xu, Z1
Hou, M1
Yang, B1
Chen, L1
Ji, M1
Elmasry, A1
Aladeeb, NM1
Elkaref, A1
Aboulfotouh, N1
Sundaraneedi, MK1
Eichenberger, RM1
Pickering, D1
Smout, MJ2
Rajan, S1
Wangchuk, P1
Keene, FR1
Collins, JG1
Beshay, EVN1
Rady, AA1
Afifi, AF1
Mohamed, AH1
Pakharukova, MY2
Pakharukov, YV1
Mordvinov, VA2
Guimarães, MA1
de Oliveira, RN1
de Almeida, RL1
Mafud, AC1
Sarkis, ALV1
Ganassin, R1
da Silva, MP1
Roquini, DB1
Veras, LM1
Sawada, TCH1
Ropke, CD1
Muehlmann, LA1
Joanitti, GA1
Kuckelhaus, SAS1
Allegretti, SM3
Mascarenhas, YP1
Leite, JRSA1
Kang, N1
Shen, W1
Gao, H1
Feng, Y1
Zhu, W1
Yang, S1
Liu, Y1
Xu, Q1
Yu, D1
Silva, LD1
Lima, NF1
Arrua, EC1
Vinaud, MC1
Wolfe, AR1
Neitz, RJ1
Burlingame, M1
Suzuki, BM1
Lim, KC1
Scheideler, M1
Nelson, DL1
Benet, LZ1
Caffrey, CR1
Oliveira, RN1
Corrêa, SAP1
Vieira, KM1
Mendes, T1
Miguel, DC1
Dias, MV1
Castro, AP1
Souza-Silva, TG1
Avgustinovich, D1
Tsyganov, M1
Vishnivetskaya, G1
Kovner, A1
Sorokina, I1
Orlovskaya, I1
Toporkova, L1
Goiman, E1
Tolstikova, T1
Dushkin, A1
Lyakhov, N1
Mordvinov, V1
Khayeka-Wandabwa, C1
Zhou, G1
Magak, NG1
Choge, JK1
Kemei, WK1
Makwali, JA1
Karani, LW1
Kisavi, MP1
Ndulu, JV1
Anjili, CO1
Malagón, D1
Botterill, B1
Gray, DJ1
Lovas, E1
Duke, M1
Gray, C1
Kopp, SR1
Knott, LM1
McManus, DP3
Daly, NL1
Mulvenna, J1
Craik, DJ1
Jones, MK2
You, H1
Hu, W1
Brindley, PJ2
Liang, XL1
Yuan, JY1
Frezza, TF1
Gremião, MP1
Zanotti-Magalhães, EM1
Magalhães, LA1
de Souza, AL1
Attia, YM1
Elalkamy, EF1
Hammam, OA3
Mahmoud, SS1
El-Khatib, AS1
Wonkchalee, N1
Boonmars, T1
Laummaunwai, P1
Aromdee, C1
Hahnvajanawong, C1
Sriraj, P1
Aukkanimart, R1
Chamgramol, Y2
Pairojkul, C2
Juasook, A1
Sudsarn, P1
Wang, W6
Li, HJ5
Qu, GL5
Xing, YT4
Yang, ZK2
Dai, JR5
Liang, YS6
Li, TY1
Ji, Y1
Qian, YL1
Farid, A1
Malek, AA1
Rabie, I1
Helmy, A1
El Amir, AM1
Dong, L1
Duan, W1
Chen, J1
Sun, H2
Qiao, C1
Xia, CM3
Palomares-Alonso, F1
Palencia Hernández, G1
Rojas-Tomé, IS1
Jung-Cook, H1
Pinzón-Estrada, E1
Mossallam, SF1
El-Faham, MH1
Deenonpoe, R1
Chomvarin, C1
Sripa, B1
Shilov, AG1
Pirozhkova, DS1
Katokhin, AV1
Woolsey, ID1
Fredensborg, BL1
Jensen, PM1
Kapel, CM1
Meyling, NV1
Kalenda, YD1
Kato, K1
Goto, Y1
Fujii, Y1
Hamano, S1
Rodriguez, S1
Zimic, M1
Castillo, Y1
Praet, N1
Gabriël, S1
Gilman, RH1
Dorny, P1
Chuah, C1
Nawaratna, SK1
Burke, ML1
Owen, HC1
Ramm, GA1
Ramadan, AA1
Eraky, MA1
El-Kholy, AA1
Rashed, GA1
Moharam, AF1
Abou-Ouf, EA1
Aly, NS1
Kishik, SM1
Abdallah, KF1
Hamdan, DI1
Guidi, A1
Lalli, C1
Perlas, E1
Bolasco, G1
Nibbio, M1
Monteagudo, E1
Bresciani, A1
Ruberti, G1
Othman, AA1
Shoheib, ZS1
Abdel-Aleem, GA1
Shareef, MM1
Yadav, AK2
Tangpu, V1
Rong, R1
Lu, ZX1
Shi, CJ1
Xu, J2
Zhang, HQ1
Gong, W1
Luo, W1
Sangweme, D1
Shiff, C1
Kumar, N2
Xiao, SH4
Mei, JY3
Jiao, PY3
Kim, TI1
Yoo, WG1
Li, S3
Hong, ST3
Hong, SJ1
Li, T1
Yang, Z1
Cai, HJ1
Song, LW1
Lu, KY1
Zhou, Z1
Wu, ZD2
Vennerstrom, JL1
Sheweita, SA1
Hassan, M1
Bahashwan, SA1
Qian, CY2
Song, LJ2
Hua, WQ1
Yin, XR2
Wang, J2
Xu, YL1
Yu, CX2
Xue, J1
Xu, LL1
Zhang, YN1
Qiang, HQ1
Zheng, X1
Fang, Y1
Duan, C1
Yao, B1
Manneck, T1
Yongvanit, P1
Pinlaor, S1
Bartsch, H1
El-Lakkany, NM2
El-Maadawy, W1
Ain-Shoka, A1
Badawy, A1
Hammam, O1
Ebeid, F2
Reda, ES1
Ouhtit, A1
Abdeen, SH1
El-Shabasy, EA1
Tao, YH3
Li, YZ3
Wei, JY3
el-Din, SH1
Sabra, AN1
Ferraz, J1
Souza, J1
Costa-Silva, M1
Torres, E1
Santana, A1
Lanfredi, R1
Maldonado, A1
Garcia, J1
Said, E1
Said, SA1
Elkashef, WF1
Gameil, NM1
Ammar, EM1
Soliman, MF1
Qian, K2
Jia, Y1
Jin, Y1
Ke, XD1
de Lima Aires, A1
de Azevedo Albuquerque, MC1
Silva, RA1
de Pontes Filho, NT1
de Araújo, SB1
Souza, VM1
Costa, VM1
Malagueño, E1
Wolken, S1
Böhm, C1
Schaper, R1
Schnieder, T1
Adelfio, R1
Odermatt, P1
Tesana, S1
Liu, AP1
Guo, JJ1
Wang, B1
Qiu, SJ1
Guan, W1
Zhu, XQ1
Lee, SH1
Lee, SJ1
Kho, WG1
Lee, M2
Chung, BS2
Seo, M1
Choi, MH2
Hanallah, S1
El-Lakkany, N2
Mahmoud, S1
Mousa, M1
Botros, S2
Zhang, H1
Jeon, D1
Suleiman, MI1
Akarim, EI1
Ibrahim, KE1
Saad, AM1
Mohammed, AE1
Ahmed, BM1
Sulaiman, SM1
Johansen, MV4
Ornbjerg, N1
Cioli, D1
Katz, N1
Day, TA1
Bennett, JL1
Ostlind, DA1
Mickle, WG1
Smith, SK1
Cifelli, S1
Ewanciw, DV1
El Ela, NA1
El Komy, E1
El Lakkany, N1
Diab, T1
Chollet, J2
Utzinger, J2
Barakat, R1
Noland, GS1
Graczyk, TK1
Fried, B1
Fitzgerald, EJ1
Elbiaze, M1
Andrade, ZA1
Baptista, AP1
Santana, TS1
Nosseir, M1
Lier, T1
Hjelmevoll, SO1
Vennervald, BJ1
Simonsen, GS1
Chen, H1
He, YW1
Liu, WQ1
Zhang, JH1
Hagan, P1
Gryseels, B2
Fillié, Y1
Monrad, J1
Christensen, NO2
Deelder, A1
Landa García, JI1
Alonso, E1
Gonzalez-Uriarte, J1
Rodriguez Romano, D1
el-Bahy, MM1
Noya, O1
Gonzalez-Rico, S1
Rodriguez, R1
Arrechedera, H1
Patarroyo, ME1
Alarcon de Noya, B1
Mola, PW1
Farah, IO1
Kariuki, TM1
Nyindo, M1
Blanton, RE1
King, CL1
Bogh, HO1
Nansen, P1
Moreno, MJ3
Urrea-París, MA3
Casado, N3
Rodriguez-Caabeiro, F3
You, J1
Mei, J1
Tanner, M1
Xiao, S1
Mbaye, A1
De Vlas, SJ1
Stelma, FF1
Guissé, F1
Van Lieshout, L1
Faye, D1
Diop, M1
Ly, A1
Tchuem-Tchuenté, LA1
Engels, D1
Polman, K1
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Capron, M1
Pierce, RJ1
Piper, KP1
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Hockley, DJ1
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Flisser, A2
Gonzalez, D1
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Madrazo, I1
Correa, D1
Rodriguez-Carbajal, J1
Cohen, S1
Rodriguez-del-Rosal, E1
Collado, M1
Fernandez, B1
Morris, DL2
Richards, KS2
Clarkson, MJ1
Taylor, DH2
Reffin, D1
Vercruysse, J1
Southgate, VR1
Rollinson, D1
Hilderson, H1

Reviews

5 reviews available for praziquantel and Disease Models, Animal

ArticleYear
Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models.
    PLoS neglected tropical diseases, 2020, Volume: 14, Issue:9

    Topics: Animals; Anthelmintics; Disease Models, Animal; Humans; Praziquantel; Schistosoma mansoni; Schistoso

2020
Susceptibility or resistance of praziquantel in human schistosomiasis: a review.
    Parasitology research, 2012, Volume: 111, Issue:5

    Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Resistance; Humans; Mice; Praziquantel; Schisto

2012
Schistosomiasis research and the European Community.
    Tropical and geographical medicine, 1994, Volume: 46, Issue:4 Spec No

    Topics: Clinical Trials as Topic; Disease Models, Animal; European Union; Forecasting; Glutathione Transfera

1994
Schistosoma japonicum infection in the pig as a model for human schistosomiasis japonica.
    Acta tropica, 2000, Sep-18, Volume: 76, Issue:2

    Topics: Animals; Anthelmintics; China; Denmark; Dietary Proteins; Disease Models, Animal; DNA, Helminth; Fec

2000
Vaccine strategies against schistosomiasis.
    Memorias do Instituto Oswaldo Cruz, 1992, Volume: 87 Suppl 4

    Topics: Animals; Antibodies, Helminth; Antibody-Dependent Cell Cytotoxicity; Antigens, Helminth; Disease Mod

1992

Trials

1 trial available for praziquantel and Disease Models, Animal

ArticleYear
Treatment of third-stage larvae of Toxocara cati with milbemycin oxime plus praziquantel tablets and emodepside plus praziquantel spot-on formulation in experimentally infected cats.
    Parasitology research, 2012, Volume: 111, Issue:5

    Topics: Animals; Anthelmintics; Cat Diseases; Cats; Depsipeptides; Disease Models, Animal; Drug Therapy, Com

2012

Other Studies

124 other studies available for praziquantel and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Schistosomiasis mansoni: A new therapeutic target for ubiquinol, a natural inhibitor of neutral magnesium-dependent sphingomyelinase in murine model.
    Acta tropica, 2022, Volume: 226

    Topics: Animals; Disease Models, Animal; Female; Magnesium; Mice; Pharmaceutical Preparations; Praziquantel;

2022
Pathological and immunological evaluation of different regimens of praziquantel treatment in a mouse model of Schistosoma mansoni infection.
    PLoS neglected tropical diseases, 2022, Volume: 16, Issue:4

    Topics: Animals; Anthelmintics; Disease Models, Animal; Granuloma; Mice; Praziquantel; Schistosoma mansoni;

2022
Schistosomicidal and hepatoprotective activity of gamma-aminobutyric acid (GABA) alone or combined with praziquantel against Schistosoma mansoni infection in murine model.
    Experimental parasitology, 2022, Volume: 238

    Topics: Animals; Anthelmintics; Disease Models, Animal; gamma-Aminobutyric Acid; Liver; Mice; Praziquantel;

2022
The Effect of Different Formulations of Praziquantel in Reducing Worms in the Prepatent Period of Schistosomiasis in Murine Models.
    Frontiers in public health, 2022, Volume: 10

    Topics: Animals; Disease Models, Animal; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis; Schistoso

2022
Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection.
    PLoS neglected tropical diseases, 2022, Volume: 16, Issue:7

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Calcium; Disease Models, Animal; Iron; Liver; Maln

2022
In Vivo Evaluation of Praziquantel-Loaded Solid Lipid Nanoparticles against
    International journal of molecular sciences, 2022, Aug-22, Volume: 23, Issue:16

    Topics: Animals; Disease Models, Animal; Drug Carriers; Lipids; Liposomes; Mice; Nanoparticles; Particle Siz

2022
Antischistosomal effects of green and chemically synthesized silver nanoparticles: In vitro and in vivo murine model.
    Acta tropica, 2023, Volume: 244

    Topics: Animals; Anthelmintics; Disease Models, Animal; Granuloma; Metal Nanoparticles; Mice; Praziquantel;

2023
Praziquantel ameliorates CCl
    British journal of pharmacology, 2019, Volume: 176, Issue:24

    Topics: Animals; Carbon Tetrachloride; Cell Line; Disease Models, Animal; Gene Expression; Hepatic Stellate

2019
Recombinant Sj16 protein with novel activity alleviates hepatic granulomatous inflammation and fibrosis induced by Schistosoma japonicum associated with M2 macrophages in a mouse model.
    Parasites & vectors, 2019, Sep-23, Volume: 12, Issue:1

    Topics: Animals; Anthelmintics; Disease Models, Animal; Fibrosis; Granuloma; Helminth Proteins; Immunologic

2019
Enhancement of the therapeutic efficacy of praziquantel in murine Schistosomiasis mansoni using silica nanocarrier.
    Parasitology research, 2019, Volume: 118, Issue:12

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Disease Models, Animal; Drug Carriers; Drug Delive

2019
Liver damage in schistosomiasis is reduced by adipose tissue-derived stem cell therapy after praziquantel treatment.
    PLoS neglected tropical diseases, 2020, Volume: 14, Issue:8

    Topics: Adipose Tissue; Animals; Cell- and Tissue-Based Therapy; Cytokines; Disease Models, Animal; Granulom

2020
Single oral fixed-dose praziquantel-miltefosine nanocombination for effective control of experimental schistosomiasis mansoni.
    Parasites & vectors, 2020, Sep-15, Volume: 13, Issue:1

    Topics: Administration, Oral; Animals; Disease Models, Animal; Drug Combinations; Drug Compounding; Female;

2020
Evaluation of prophylactic efficacy and safety of praziquantel-miltefosine nanocombination in experimental Schistosomiasis mansoni.
    Acta tropica, 2020, Volume: 212

    Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Carriers; Drug Combinations; Granuloma; Lipids;

2020
In vivo assessment of the antischistosomal activity of curcumin loaded nanoparticles versus praziquantel in the treatment of Schistosoma mansoni.
    Scientific reports, 2020, 09-25, Volume: 10, Issue:1

    Topics: Animals; Anthelmintics; Curcumin; Disease Models, Animal; Drug Synergism; Female; Gold; Male; Metal

2020
Antischistosomal properties of aurone derivatives against juvenile and adult worms of Schistosoma mansoni.
    Acta tropica, 2021, Volume: 213

    Topics: Animals; Benzofurans; Disease Models, Animal; Female; Flavonoids; Mice; Parasitic Sensitivity Tests;

2021
In vitro and in vivo evaluation of cnicin from blessed thistle (Centaurea benedicta) and its inclusion complexes with cyclodextrins against Schistosoma mansoni.
    Parasitology research, 2021, Volume: 120, Issue:4

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Oral; Animals; beta-Cyclodextrins; Centaurea; Dis

2021
Doxycycline aggravates granulomatous inflammation and lung microstructural remodeling induced by Schistosoma mansoni infection.
    International immunopharmacology, 2021, Volume: 94

    Topics: Airway Remodeling; Animals; Anthelmintics; Cytokines; Disease Models, Animal; Doxycycline; Granuloma

2021
Effect of celecoxib against different developmental stages of experimental Schistosoma mansoni infection.
    Acta tropica, 2021, Volume: 218

    Topics: Administration, Oral; Animals; Anthelmintics; Apoptosis; Celecoxib; Disease Models, Animal; Female;

2021
Immunomics-Guided Antigen Discovery for Praziquantel-Induced Vaccination in Urogenital Human Schistosomiasis.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Computational Biology; Disease Models, Animal; Ep

2021
Neurological impairment caused by Schistosoma mansoni systemic infection exhibits early features of idiopathic neurodegenerative disease.
    The Journal of biological chemistry, 2021, Volume: 297, Issue:2

    Topics: Acetylcysteine; Animals; Anthelmintics; Astrocytes; Deferoxamine; Disease Models, Animal; Free Radic

2021
Parasitological and Biochemical Efficacy of the Active Ingredients of
    Molecules (Basel, Switzerland), 2021, Jul-27, Volume: 26, Issue:15

    Topics: Animals; Antioxidants; Curcuma; Curcumin; Disease Models, Animal; Disulfides; DNA Fragmentation; Fem

2021
Repurposing the anthelmintic praziquantel to treat psoriasis.
    British journal of pharmacology, 2021, Volume: 178, Issue:23

    Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Repositioning; Mice; Mice, Inbred BALB C; Prazi

2021
Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis.
    Parasitology international, 2017, Volume: 66, Issue:5

    Topics: Anilides; Animals; Cercaria; Disease Models, Animal; Drug Therapy, Combination; Egypt; Female; Hedge

2017
Antischistosomal Activity of Pyrido[1,2-a]benzimidazole Derivatives and Correlation with Inhibition of β-Hematin Formation.
    ACS infectious diseases, 2017, 06-09, Volume: 3, Issue:6

    Topics: Animals; Benzimidazoles; Disease Models, Animal; Female; Hemeproteins; Inhibitory Concentration 50;

2017
Radiological evolution of porcine neurocysticercosis after combined antiparasitic treatment with praziquantel and albendazole.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:6

    Topics: Albendazole; Animals; Anthelmintics; Brain; Cysts; Disease Models, Animal; Drug Therapy, Combination

2017
Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:6

    Topics: Animals; Anthelmintics; ATP-Binding Cassette Transporters; Disease Models, Animal; Drug Resistance;

2017
Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:9

    Topics: Animals; Anthelmintics; Chemoprevention; Chromatography, Liquid; Dexamethasone; Disease Models, Anim

2017
Praziquantel treatment after Schistosoma japonicum infection maintains hepatic insulin sensitivity and improves glucose metabolism in mice.
    Parasites & vectors, 2017, Oct-02, Volume: 10, Issue:1

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Cell Line; Chronic Disease; Cytokines; Disease Mod

2017
Simvastatin exerts antifibrotic effect and potentiates the antischistosomal effects of praziquantel in a murine model: Role of IL10.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 96

    Topics: Animals; Anthelmintics; Antifibrinolytic Agents; Disease Models, Animal; Drug Therapy, Combination;

2017
Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:12

    Topics: Acetylcholinesterase; Animals; Biological Transport; Cholinesterase Inhibitors; Disease Models, Anim

2017
Schistosomicidal, antifibrotic and antioxidant effects of Cucurbita pepo L. seed oil and praziquantel combined treatment for Schistosoma mansoni infection in a mouse model.
    Journal of helminthology, 2019, Volume: 93, Issue:3

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Antioxidants; Cucurbita; Disease Models, Animal; D

2019
Effects of miconazole/clotrimazole and praziquantel combinations against the liver fluke Opisthorchis felineus in vivo and in vitro.
    Parasitology research, 2018, Volume: 117, Issue:7

    Topics: Animals; Anthelmintics; Clotrimazole; Cricetinae; Disease Models, Animal; Drug Therapy, Combination;

2018
Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Alkaloids; Animals; Cell Line; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Inbred BALB

2018
Antischistosomal Properties of Hederacolchiside A1 Isolated from
    Molecules (Basel, Switzerland), 2018, Jun-13, Volume: 23, Issue:6

    Topics: Animals; Artemisinins; Artesunate; Disease Models, Animal; Female; Mice; Plant Extracts; Praziquante

2018
In vivo treatment of experimental neurocysticercosis with praziquantel nanosuspensions-a metabolic approach.
    Drug delivery and translational research, 2018, Volume: 8, Issue:5

    Topics: Animals; Anthelmintics; Cysticercus; Disease Models, Animal; Drug Stability; Metabolome; Metabolomic

2018
TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling.
    International journal for parasitology. Drugs and drug resistance, 2018, Volume: 8, Issue:3

    Topics: Administration, Oral; Animals; Arylsulfonates; Disease Models, Animal; Drug Discovery; Female; Liver

2018
In vitro schistosomicidal activity of tamoxifen and its effectiveness in a murine model of schistosomiasis at a single dose.
    Parasitology research, 2019, Volume: 118, Issue:5

    Topics: Animals; Disease Models, Animal; Drug Resistance; Feces; Female; Male; Mice; Mice, Inbred BALB C; Pr

2019
Doxycycline hyclate: A schistosomicidal agent in vitro with immunomodulatory potential on granulomatous inflammation in vivo.
    International immunopharmacology, 2019, Volume: 70

    Topics: Animals; Antimalarials; Cells, Cultured; Disease Models, Animal; Doxycycline; Granuloma; Humans; Imm

2019
Effects of supramolecular complexation of praziquantel with disodium glycyrrhizinate on the liver fluke Opisthorchis felineus: An in vitro and in vivo study.
    Acta tropica, 2019, Volume: 194

    Topics: Animals; Anthelmintics; Cricetinae; Disease Models, Animal; Glycyrrhizic Acid; Male; Mesocricetus; O

2019
Combined chemotherapy manifest less severe immunopathology effects in helminth-protozoa comorbidity.
    Experimental parasitology, 2019, Volume: 204

    Topics: Analysis of Variance; Animals; Anthelmintics; Antimony Sodium Gluconate; Antiprotozoal Agents; Chemo

2019
Anthelminthic activity of the cyclotides (kalata B1 and B2) against schistosome parasites.
    Biopolymers, 2013, Volume: 100, Issue:5

    Topics: Animals; Anthelmintics; Cyclotides; Disease Models, Animal; Humans; Parasites; Praziquantel; Schisto

2013
Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII.
    PLoS pathogens, 2013, Volume: 9, Issue:3

    Topics: Animals; Anthelmintics; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disea

2013
Effect of Chinese herbal compound on liver fibrosis in rabbits with schistosomiasis by B-ultrasound.
    Asian Pacific journal of tropical medicine, 2013, Volume: 6, Issue:8

    Topics: Angelica sinensis; Animals; Anthelmintics; Disease Models, Animal; Herbal Medicine; Liver; Liver Cir

2013
Liposomal-praziquantel: efficacy against Schistosoma mansoni in a preclinical assay.
    Acta tropica, 2013, Volume: 128, Issue:1

    Topics: Animals; Anthelmintics; Biological Availability; Disease Models, Animal; Drug Carriers; Drug Evaluat

2013
Telmisartan, an AT1 receptor blocker and a PPAR gamma activator, alleviates liver fibrosis induced experimentally by Schistosoma mansoni infection.
    Parasites & vectors, 2013, Jul-05, Volume: 6

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anthelmintics; Benzimidazoles; Benzoates; Disease

2013
A combination of praziquantel and the traditional medicinal plant Thunbergia laurifolia on Opisthorchis viverrini infection and cholangiocarcinoma in a hamster model.
    Parasitology research, 2013, Volume: 112, Issue:12

    Topics: Acanthaceae; Alanine Transaminase; Alkaline Phosphatase; Animals; Anthelmintics; Anti-Inflammatory A

2013
Is there a reduced sensitivity of dihydroartemisinin against praziquantel-resistant Schistosoma japonicum?
    Parasitology research, 2014, Volume: 113, Issue:1

    Topics: Animals; Artemisinins; Disease Models, Animal; Drug Resistance; Female; Mice; Mice, Inbred ICR; Praz

2014
Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum.
    Parasitology research, 2014, Volume: 113, Issue:3

    Topics: Administration, Oral; Animals; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Drug Re

2014
Overview on cysteine protease inhibitors as chemotherapy for Schistosomiasis mansoni in mice and also its effect on the parasitological and immunological profile.
    Pakistan journal of biological sciences : PJBS, 2013, Dec-15, Volume: 16, Issue:24

    Topics: Animals; Cysteine Proteinase Inhibitors; Disease Models, Animal; Granuloma; Intestines; Liver; Male;

2013
An artemisinin derivative of praziquantel as an orally active antischistosomal agent.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Administration, Oral; Animals; Artemisinins; Disease Models, Animal; Female; Mice; Mice, Inbred ICR;

2014
Murine cysticercosis model: influence of the infection time and the time of treatment on the cysticidal efficacy of albendazole and praziquantel.
    Experimental parasitology, 2015, Volume: 149

    Topics: Albendazole; Animals; Anthelmintics; Cysticercosis; Cysticercus; Disease Models, Animal; Drug Admini

2015
Efficacy of Synriam™, a new antimalarial combination of OZ277 and piperaquine, against different developmental stages of Schistosoma mansoni.
    Acta tropica, 2015, Volume: 143

    Topics: Adolescent; Animals; Antimalarials; Cricetinae; Disease Models, Animal; Drug Combinations; Heterocyc

2015
The carcinogenic liver fluke Opisthorchis viverrini is a reservoir for species of Helicobacter.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:5

    Topics: Animals; Anthelmintics; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Cricetina

2015
The first comprehensive study of praziquantel effects in vivo and in vitro on European liver fluke Opisthorchis felineus (Trematoda).
    International journal of antimicrobial agents, 2015, Volume: 46, Issue:1

    Topics: Animals; Anthelmintics; Disease Models, Animal; Histocytochemistry; Inhibitory Concentration 50; Loc

2015
An insect-tapeworm model as a proxy for anthelminthic effects in the mammalian host.
    Parasitology research, 2015, Volume: 114, Issue:7

    Topics: Animals; Anthelmintics; Cestoda; Cestode Infections; Coleoptera; Disease Models, Animal; Female; Hum

2015
Tandem repeat recombinant proteins as potential antigens for the sero-diagnosis of Schistosoma mansoni infection.
    Parasitology international, 2015, Volume: 64, Issue:6

    Topics: Animals; Anthelmintics; Antibodies, Helminth; Antigens, Helminth; Biomarkers; Disease Models, Animal

2015
Successful Antiparasitic Treatment for Cysticercosis is Associated with a Fast and Marked Reduction of Circulating Antigen Levels in a Naturally Infected Pig Model.
    The American journal of tropical medicine and hygiene, 2015, Volume: 93, Issue:6

    Topics: Albendazole; Animals; Anticestodal Agents; Antigens, Helminth; Benzimidazoles; Cysticercosis; Diseas

2015
Characterising granuloma regression and liver recovery in a murine model of schistosomiasis japonica.
    International journal for parasitology, 2016, Volume: 46, Issue:4

    Topics: Animals; Anthelmintics; Disease Models, Animal; Eosinophils; Female; Granuloma; Immunohistochemistry

2016
Miltefosine lipid nanocapsules: Intersection of drug repurposing and nanotechnology for single dose oral treatment of pre-patent schistosomiasis mansoni.
    Acta tropica, 2016, Volume: 159

    Topics: Administration, Oral; Animals; Disease Models, Animal; Drug Repositioning; Granuloma; Liver; Mice; N

2016
Dose-response relationship in Schistosoma mansoni juvenile and adult stages following limonin treatment in experimentally infected mice.
    Parasitology research, 2016, Volume: 115, Issue:10

    Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resist

2016
Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems.
    PLoS neglected tropical diseases, 2016, Volume: 10, Issue:8

    Topics: Animals; Disease Models, Animal; Drug Resistance; Female; Genitalia; Half-Life; Humans; Life Cycle S

2016
Experimental schistosomal hepatitis: protective effect of coenzyme-Q10 against the state of oxidative stress.
    Experimental parasitology, 2008, Volume: 120, Issue:2

    Topics: Actins; Animals; Anthelmintics; Aryldialkylphosphatase; Biomphalaria; Carboxylic Ester Hydrolases; D

2008
Anticestodal activity of Adhatoda vasica extract against Hymenolepis diminuta infections in rats.
    Journal of ethnopharmacology, 2008, Sep-26, Volume: 119, Issue:2

    Topics: Animals; Anthelmintics; Disease Models, Animal; Female; Hymenolepiasis; Hymenolepis diminuta; India;

2008
Schistosoma japonicum: a PCR assay for the early detection and evaluation of treatment in a rabbit model.
    Experimental parasitology, 2009, Volume: 121, Issue:2

    Topics: Animals; Anthelmintics; Disease Models, Animal; DNA, Helminth; Enzyme-Linked Immunosorbent Assay; Fe

2009
Plasmodium yoelii: adverse outcome of non-lethal P. yoelii malaria during co-infection with Schistosoma mansoni in BALB/c mouse model.
    Experimental parasitology, 2009, Volume: 122, Issue:3

    Topics: Anemia; Animals; Anthelmintics; Disease Models, Animal; Female; Hematocrit; Hepatomegaly; Malaria; M

2009
Further study on mefloquine concerning several aspects in experimental treatment of mice and hamsters infected with Schistosoma japonicum.
    Parasitology research, 2009, Volume: 106, Issue:1

    Topics: Administration, Oral; Animals; Anthelmintics; Cricetinae; Disease Models, Animal; Female; Hepatic Ve

2009
Efficacy of artesunate and artemether against Clonorchis sinensis in rabbits.
    Parasitology research, 2009, Volume: 106, Issue:1

    Topics: Administration, Oral; Animals; Anthelmintics; Artemether; Artemisinins; Artesunate; Bile Ducts; Clon

2009
Effects of in vitro cultivated Calculus Bovis compound on pulmonary lesions in rabbits with schistosomiasis.
    World journal of gastroenterology, 2010, Feb-14, Volume: 16, Issue:6

    Topics: Animals; Anthelmintics; Bilirubin; Disease Models, Animal; Drugs, Chinese Herbal; Fibronectins; Hype

2010
Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:9

    Topics: Administration, Oral; Androgen Antagonists; Animals; Anthelmintics; Disease Models, Animal; Female;

2010
Schistosoma mansoni changes the activity of phase II drug-metabolizing enzymes: role of praziquantel as antibilharzial drug.
    Drug metabolism letters, 2010, Volume: 4, Issue:3

    Topics: Animals; Disease Models, Animal; Glutathione; Glutathione Reductase; Glutathione Transferase; Liver;

2010
Schistosoma japonicum-infected hamsters (Mesocricetus auratus) used as a model in experimental chemotherapy with praziquantel, artemether, and OZ compounds.
    Parasitology research, 2011, Volume: 108, Issue:2

    Topics: Animals; Cricetinae; Disease Models, Animal; Female; Heterocyclic Compounds; Host-Parasite Interacti

2011
Effect of mefloquine administered orally at single, multiple, or combined with artemether, artesunate, or praziquantel in treatment of mice infected with Schistosoma japonicum.
    Parasitology research, 2011, Volume: 108, Issue:2

    Topics: Administration, Oral; Animals; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Dose-Re

2011
Kinetics of circulating antigen 14-3-3 in sera of rabbits firstly infected with Schistosoma japonicum and treated with/without praziquantel.
    Parasitology research, 2011, Volume: 108, Issue:2

    Topics: Animals; Anthelmintics; Antigens, Helminth; Disease Models, Animal; Enzyme-Linked Immunosorbent Assa

2011
Comparative effect of mebendazole, albendazole, tribendimidine, and praziquantel in treatment of rats infected with Clonorchis sinensis.
    Parasitology research, 2011, Volume: 108, Issue:3

    Topics: Albendazole; Animals; Antiprotozoal Agents; Clonorchiasis; Clonorchis sinensis; Disease Models, Anim

2011
Transdermal evaporation delivery system of praziquantel for schistosomiasis japonicum chemotherapy.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:7

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Anthelmintics; Biological Availability; Ch

2011
Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:8

    Topics: Administration, Oral; Animals; Anthelmintics; Disease Models, Animal; Dose-Response Relationship, Dr

2011
Oxidative and nitrative DNA damage: key events in opisthorchiasis-induced carcinogenesis.
    Parasitology international, 2012, Volume: 61, Issue:1

    Topics: Animals; Anthelmintics; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Cyclooxyg

2012
Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:10

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anthelmintics; Disease Models, Animal; Drug Therap

2011
Structural changes of Schistosoma mansoni adult worms recovered from C57BL/6 mice treated with radiation-attenuated vaccine and/or praziquantel against infection.
    Parasitology research, 2012, Volume: 110, Issue:2

    Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Therapy, Combination; Female; Immunotherapy; Ma

2012
Dihydroartemisinin-praziquantel combinations and multiple doses of dihydroartemisinin in the treatment of Schistosoma japonicum in experimentally infected mice.
    Annals of tropical medicine and parasitology, 2011, Volume: 105, Issue:4

    Topics: Animals; Anthelmintics; Artemisinins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug

2011
Pharmacodynamics of mefloquine and praziquantel combination therapy in mice harbouring juvenile and adult Schistosoma mansoni.
    Memorias do Instituto Oswaldo Cruz, 2011, Volume: 106, Issue:7

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female

2011
Effect of praziquantel on adult Echinostoma paraensei worms in experimentally infected mice.
    Parasitology research, 2012, Volume: 111, Issue:1

    Topics: Animals; Anthelmintics; Disease Models, Animal; Echinostoma; Echinostomiasis; Female; Mice; Microsco

2012
Tranilast ameliorates impaired hepatic functions in Schistosoma mansoni-infected mice.
    Inflammopharmacology, 2012, Volume: 20, Issue:2

    Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Therapy, Combination; Liver Cirrhosis; Liver Di

2012
Evaluation of avocado/soybean unsaponifiable alone or concurrently with praziquantel in murine schistosomiasis.
    Acta tropica, 2012, Volume: 122, Issue:3

    Topics: Administration, Oral; Animals; Anthelmintics; Cytokines; Disease Models, Animal; Drug Therapy, Combi

2012
[Studies on resistance of Schistosoma to praziquantel XIII resistance of Schistosoma japonicum to praziquantel is experimentally induced in laboratory].
    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control, 2011, Volume: 23, Issue:6

    Topics: Animals; Cercaria; China; Disease Models, Animal; Drug Resistance; Female; Humans; Liver; Male; Mice

2011
[Studies on resistance of Schistosoma to praziquantel XIV experimental comparison of susceptibility to praziquantel between PZQ-resistant isolates and PZQ-susceptible isolates of Schistosoma japonicum in stages of adult worms, miracidia and cercariae].
    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control, 2011, Volume: 23, Issue:6

    Topics: Animals; Cercaria; China; Disease Models, Animal; Drug Resistance; Female; Humans; Life Cycle Stages

2011
In vivo anthelmintic activity of Clerodendrum colebrookianum Walp., a traditionally used taenicidal plant in Northeast India.
    Parasitology research, 2012, Volume: 111, Issue:4

    Topics: Animals; Anthelmintics; Clerodendrum; Disease Models, Animal; Feces; Female; Hymenolepiasis; Hymenol

2012
Characterization of IgG responses of rabbits to Sj14-3-3 protein after experimental infection with Schistosoma japonicum.
    Parasitology research, 2012, Volume: 111, Issue:5

    Topics: 14-3-3 Proteins; Animals; Anthelmintics; Antibodies, Helminth; Disease Models, Animal; Enzyme-Linked

2012
Immunohistopathological changes in murine Schistosomiasis mansoni under the influence of N-acetyl-L-cysteine.
    Parasitology research, 2012, Volume: 111, Issue:4

    Topics: Acetylcysteine; Administration, Oral; Animals; Anthelmintics; Anti-Inflammatory Agents; Disease Mode

2012
Activity of tribendimidine and praziquantel combination therapy against the liver fluke Opisthorchis viverrini in vitro and in vivo.
    Journal of helminthology, 2013, Volume: 87, Issue:2

    Topics: Animals; Cricetinae; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Inhibitory C

2013
The sources and metabolic dynamics of Schistosoma japonicum DNA in serum of the host.
    Parasitology research, 2013, Volume: 112, Issue:1

    Topics: Animals; Anthelmintics; Coinfection; Disease Models, Animal; DNA, Helminth; Female; Male; Praziquant

2013
Sustained-release praziquantel tablet: pharmacokinetics and the treatment of clonorchiasis in beagle dogs.
    Parasitology research, 2003, Volume: 91, Issue:4

    Topics: Animals; Anthelmintics; Area Under Curve; Clonorchiasis; Clonorchis sinensis; Disease Models, Animal

2003
Altered immunoglobulin isotype profile and anti-immature worm surface immunoglobulins in mice harboring a praziquantel-resistant Schistosoma mansoni isolate.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2003, Volume: 111, Issue:12

    Topics: Animals; Anthelmintics; Antibodies, Helminth; Disease Models, Animal; Drug Resistance; Granuloma; Im

2003
Development of resistance to reinfection by Clonorchis sinensis in rats.
    The Korean journal of parasitology, 2004, Volume: 42, Issue:1

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Clonorchiasis; Clonorchis sinensis; Cricetinae; Di

2004
Antischistosomal effects of praziquantel, its alkaline hydrolysis and sun decomposed products on experimentally S. mansoni infected albino mice. (A) Efficacy assessment based on clinicopathological findings.
    Journal of the Egyptian Society of Parasitology, 2004, Volume: 34, Issue:1

    Topics: Administration, Oral; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Feces; Female;

2004
Prenatal Schistosoma japonicum infection in piglets: effect of repeated exposure of the dams on treatment efficacy and susceptibility to challenge infections.
    The Journal of parasitology, 2004, Volume: 90, Issue:2

    Topics: Animals; Anthelmintics; Cecum; Disease Models, Animal; Disease Susceptibility; Feces; Female; Liver;

2004
Lack of evidence for an antischistosomal activity of myrrh in experimental animals.
    The American journal of tropical medicine and hygiene, 2004, Volume: 71, Issue:2

    Topics: Animals; Anthelmintics; Cricetinae; Disease Models, Animal; Female; Humans; Male; Mesocricetus; Mice

2004
The Hymenolepis diminuta-golden hamster (Mesocricetus auratus) model for the evaluation of gastrointestinal anticestode activity.
    The Journal of parasitology, 2004, Volume: 90, Issue:4

    Topics: Administration, Oral; Amidines; Animals; Anticestodal Agents; Cambendazole; Cricetinae; Digestive Sy

2004
Triclabendazole and its two main metabolites lack activity against Schistosoma mansoni in the mouse model.
    The American journal of tropical medicine and hygiene, 2006, Volume: 75, Issue:2

    Topics: Animals; Anthelmintics; Benzimidazoles; Disease Models, Animal; Feces; Female; Liver; Male; Mesenter

2006
Exacerbation of Plasmodium yoelii malaria in Echinostoma caproni infected mice and abatement through anthelmintic treatment.
    The Journal of parasitology, 2005, Volume: 91, Issue:4

    Topics: Animals; Anthelmintics; Disease Models, Animal; Echinostomiasis; Malaria; Male; Mice; Mice, Inbred B

2005
[Thoracic hydatid cysts: news].
    Revue des maladies respiratoires, 2006, Volume: 23, Issue:4 Pt 2

    Topics: Albendazole; Animals; Anthelmintics; Anticestodal Agents; Antinematodal Agents; Benzimidazoles; Dise

2006
Remodeling of hepatic vascular changes after specific chemotherapy of schistosomal periportal fibrosis.
    Memorias do Instituto Oswaldo Cruz, 2006, Volume: 101 Suppl 1

    Topics: Animals; Anthelmintics; Chronic Disease; Disease Models, Animal; Female; Granuloma; Humans; Liver Ci

2006
Pharmacodynamics of pentoxifylline and/or praziquantel in murine schistosomiasis mansoni.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2007, Volume: 115, Issue:3

    Topics: Animals; Anthelmintics; Disease Models, Animal; Granuloma; Male; Mice; Pentoxifylline; Praziquantel;

2007
Real-time PCR for detection of low intensity Schistosoma japonicum infections in a pig model.
    Acta tropica, 2008, Volume: 105, Issue:1

    Topics: Animals; Disease Models, Animal; DNA, Helminth; DNA, Mitochondrial; Electron Transport Complex I; Fe

2008
Rosiglitazone prevents murine hepatic fibrosis induced by Schistosoma japonicum.
    World journal of gastroenterology, 2008, May-14, Volume: 14, Issue:18

    Topics: Actins; Animals; Anthelmintics; Collagen Type I; Collagen Type III; Disease Models, Animal; Hypoglyc

2008
Experimental Schistosoma bovis infection in goats. Circulating antigen and antibody responses to egg and adult worm antigens during infection and following treatment with praziquantel.
    Parasitology, 1996, Volume: 113 ( Pt 4)

    Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Antiplatyhelmintic Agents; Disease Models, Animal

1996
Evaluation of scolicidal agents in an experimental hydatid disease model.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1997, Volume: 29, Issue:3

    Topics: Animals; Anti-Infective Agents, Local; Antiplatyhelmintic Agents; Disease Models, Animal; Echinococc

1997
Comparative studies on the effect of bithionol, praziquantel and triclabendazole in rabbit's fascioliasis.
    Journal of the Egyptian Society of Parasitology, 1997, Volume: 27, Issue:2

    Topics: Animals; Anthelmintics; Benzimidazoles; Bithionol; Disease Models, Animal; Fasciola; Fascioliasis; P

1997
Schistosoma mansoni infection in owl monkeys (Aontus nancymai): evidence for the early elimination of adult worms.
    Acta tropica, 1998, Jul-30, Volume: 70, Issue:3

    Topics: Animals; Aotidae; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Feces; Granuloma; Hemat

1998
Cytokine control of the granulomatous response in Schistosoma mansoni-infected baboons: role of exposure and treatment.
    Infection and immunity, 1999, Volume: 67, Issue:12

    Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Cytokines; Disease Models, Animal; Feces; Granulo

1999
Praziquantel and albendazole in the combined treatment of experimental hydatid disease.
    Parasitology research, 2001, Volume: 87, Issue:3

    Topics: Albendazole; Animals; Anthelmintics; Disease Models, Animal; Drug Therapy, Combination; Echinococcos

2001
Chemoprophylactic praziquantel treatment in experimental hydatidosis.
    Parasitology research, 2001, Volume: 87, Issue:6

    Topics: Animals; Anthelmintics; Disease Models, Animal; Echinococcosis; Echinococcus; Female; Mice; Praziqua

2001
Effect of combined treatment with praziquantel and artemether on Schistosoma japonicum and Schistosoma mansoni in experimentally infected animals.
    Acta tropica, 2001, Sep-01, Volume: 80, Issue:1

    Topics: Administration, Oral; Animals; Anthelmintics; Artemether; Artemisinins; Cricetinae; Disease Models,

2001
Combined praziquantel and albendazole chemoprophylaxis in experimental hydatidosis.
    Parasitology research, 2001, Volume: 87, Issue:9

    Topics: Albendazole; Animals; Anthelmintics; Disease Models, Animal; Drug Therapy, Combination; Echinococcos

2001
Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence.
    Tropical medicine & international health : TM & IH, 2001, Volume: 6, Issue:11

    Topics: Animals; Anthelmintics; Disease Models, Animal; Disease Outbreaks; Drug Resistance; Feces; Humans; M

2001
Adverse effects of praziquantel treatment of Schistosoma japonicum infection: involvement of host anaphylactic reactions induced by parasite antigen release.
    International journal for parasitology, 2002, Volume: 32, Issue:4

    Topics: Anaphylaxis; Animals; Antibodies, Helminth; Antigens, Helminth; Disease Models, Animal; Female; Huma

2002
Schistosoma mansoni: larval damage and role of effector cell(s) in the synergy between vaccine immunity and praziquantel treatment.
    Parasitology, 1991, Volume: 103 Pt 2

    Topics: Animals; Disease Models, Animal; Eosinophils; Female; Guinea Pigs; Larva; Leukocyte Count; Mice; Mic

1991
Praziquantel treatment of porcine brain and muscle Taenia solium cysticercosis. 1. Radiological, physiological and histopathological studies.
    Parasitology research, 1990, Volume: 76, Issue:3

    Topics: Animals; Biopsy; Brain; Cysticercosis; Cysticercus; Disease Models, Animal; Electrophysiology; Muscl

1990
Comparison of Albendazole and Praziquantel therapy of Echinococcus granulosus in naturally infected sheep.
    Veterinary parasitology, 1990, Volume: 36, Issue:1-2

    Topics: Albendazole; Animals; Disease Models, Animal; Echinococcosis; Echinococcus; Microscopy, Electron; Pr

1990
Effect of praziquantel treatment on lung-stage larvae of Schistosoma mansoni in vivo.
    Parasitology, 1989, Volume: 98 Pt 2

    Topics: Animals; Antigens, Helminth; Antigens, Surface; Aprotinin; Disease Models, Animal; Dose-Response Rel

1989
Comparison of albendazole, mebendazole and praziquantel chemotherapy of Echinococcus multilocularis in a gerbil model.
    Gut, 1989, Volume: 30, Issue:10

    Topics: Albendazole; Animals; Anthelmintics; Disease Models, Animal; Echinococcosis; Echinococcus; Gerbillin

1989
Experimental chemotherapy of Schistosoma curassoni in mice.
    Parasitology research, 1989, Volume: 75, Issue:7

    Topics: Animals; Disease Models, Animal; Female; Hycanthone; Male; Mice; Nitroquinolines; Oxamniquine; Prazi

1989