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praziquantel and Cirrhosis

praziquantel has been researched along with Cirrhosis in 14 studies

azinox: Russian drug

Research Excerpts

ExcerptRelevanceReference
"In February 1987, 322 Sudanese school children were diagnosed for Schistosoma mansoni infection and treated randomly with praziquantel (either 20 mg/kg or 40 mg/kg body weight)."9.07Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity twenty-three months after treatment with praziquantel. ( Abdel-Rahim, IM; Doehring-Schwerdtfeger, E; Ehrich, JH; Elsheikh, M; Franke, D; Kaiser, C; Kardorff, R; Mohamed-Ali, Q; Richter, J; Schlake, J, 1992)
" Recently, we demonstrated a persistent APF in over one-third of opisthorchiasis patients after worm removal by praziquantel (PZQ) treatment."8.12Persistent advanced periductal fibrosis is associated with cagA-positive Helicobacter pylori infection in post-praziquantel treatment of opisthorchiasis. ( Deenonpoe, R; Edwards, SW; Mairiang, E; Phung, HTT; Sripa, B; Suttiprapa, S, 2022)
"This study investigated the effects of nanoencapsulated curcumin (NEC) and praziquantel (PZQ) treatment on the resolution of periductal fibrosis (PDF) and bile canalicular (BC) abnormalities in Opisthorchis viverrini infected hamsters."7.83Nanoencapsulated curcumin and praziquantel treatment reduces periductal fibrosis and attenuates bile canalicular abnormalities in Opisthorchis viverrini-infected hamsters. ( Chaidee, A; Charoensuk, L; Intuyod, K; Pairojkul, C; Pinlaor, P; Pinlaor, S; Suwannateep, N; Vaeteewoottacharn, K; Wanichwecharungruang, S; Yongvanit, P, 2016)
"In February 1987, 322 Sudanese school children were diagnosed for Schistosoma mansoni infection and treated randomly with praziquantel (either 20 mg/kg or 40 mg/kg body weight)."5.07Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity twenty-three months after treatment with praziquantel. ( Abdel-Rahim, IM; Doehring-Schwerdtfeger, E; Ehrich, JH; Elsheikh, M; Franke, D; Kaiser, C; Kardorff, R; Mohamed-Ali, Q; Richter, J; Schlake, J, 1992)
" Recently, we demonstrated a persistent APF in over one-third of opisthorchiasis patients after worm removal by praziquantel (PZQ) treatment."4.12Persistent advanced periductal fibrosis is associated with cagA-positive Helicobacter pylori infection in post-praziquantel treatment of opisthorchiasis. ( Deenonpoe, R; Edwards, SW; Mairiang, E; Phung, HTT; Sripa, B; Suttiprapa, S, 2022)
" The participants with advanced periductal fibrosis (APF) by ultrasound (n = 785) were invited to undergo annual follow-up ultrasonography for five years after praziquantel treatment."4.02Hepatobiliary morbidities detected by ultrasonography in Opisthorchis viverrini-infected patients before and after praziquantel treatment: a five-year follow up study. ( Bethony, J; Brindley, PJ; Kaewkes, S; Laha, T; Loukas, A; Mairiang, E; Sripa, B, 2021)
"This study investigated the effects of nanoencapsulated curcumin (NEC) and praziquantel (PZQ) treatment on the resolution of periductal fibrosis (PDF) and bile canalicular (BC) abnormalities in Opisthorchis viverrini infected hamsters."3.83Nanoencapsulated curcumin and praziquantel treatment reduces periductal fibrosis and attenuates bile canalicular abnormalities in Opisthorchis viverrini-infected hamsters. ( Chaidee, A; Charoensuk, L; Intuyod, K; Pairojkul, C; Pinlaor, P; Pinlaor, S; Suwannateep, N; Vaeteewoottacharn, K; Wanichwecharungruang, S; Yongvanit, P, 2016)
"The purpose of this study was to examine in vivo the activity of cytochrome P450 (CYP) 2A6, an enzyme capable of activating carcinogens, including N-nitrosodimethylamine, in humans with the carcinogenic liver fluke infection, opisthorchiasis viverrini, before and after treatment with the antiparasitic agent, praziquantel."3.69Induction of cytochrome P450 2A6 expression in humans by the carcinogenic parasite infection, opisthorchiasis viverrini. ( Bartsch, H; Haswell-Elkins, MR; Lang, MA; Mairiang, E; Mairiang, P; Pelkonen, P; Satarug, S; Sithithaworn, P; Yongvanit, P, 1996)
"Metformin (Met) is a well-known drug for type 2 diabetes."1.62An adjuvant effect of Metformin as an anti-fibrotic agent when administered with the anti-schistosomal Praziquantel in Schistosoma mansoni infected mice. ( El-Naggar, SA; El-Said, KS; Harras, SF; Salama, WM, 2021)
"Schistosomiasis is one of the many illnesses endemic in Africa and approximately 40% of refugees have been found to be infected by this parasite."1.34Asymptomatic schistosomiasis in a young Sudanese refugee. ( Benson, J, 2007)
"Schistosomiasis is one of the main health problems hindering socio-economic development in Egypt."1.31Histological assessment of tissue repair after treatment of human schistosomiasis. ( Abdel-Hadi, AM; Talaat, M, 2000)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (28.57)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's4 (28.57)2.80

Authors

AuthorsStudies
Phung, HTT1
Deenonpoe, R1
Suttiprapa, S1
Mairiang, E4
Edwards, SW1
Sripa, B3
Elhenawy, AA1
Elmehankar, MS1
Nabih, N1
Elzoheiry, MA1
Hany, H1
El-Gamal, R1
Aboukamar, WA1
Shen, J1
Wang, L1
Peng, M1
Liu, Z1
Zhang, B1
Zhou, T1
Sun, X1
Wu, Z1
Laha, T1
Kaewkes, S1
Loukas, A1
Bethony, J1
Brindley, PJ1
Salama, WM1
El-Naggar, SA1
Harras, SF1
El-Said, KS1
Wangboon, C1
Yongvanit, P3
Loilome, W1
Thanan, R1
Worasith, C1
Eamudomkarn, C1
Chamadol, N1
Sithithaworn, J1
Saichua, P1
Khuntikeo, N1
Bethony, JM1
Sithithaworn, P2
Charoensuk, L1
Pinlaor, P1
Wanichwecharungruang, S1
Intuyod, K1
Vaeteewoottacharn, K1
Chaidee, A1
Pairojkul, C1
Suwannateep, N1
Pinlaor, S1
Hassan, SI1
Ali, I1
Nessim, NG1
Amer, NM1
Abd el Kader el Khafif, M1
Ashour, A1
el Mohandes, M1
Benson, J1
Abdul-Fattah, MM1
Yossef, SM1
Ebraheem, ME1
Nasr, ME1
Hassan, MA1
Abdul Wahab, SE1
Kresina, TF1
He, Q1
Degli Esposti, S1
Zern, MA1
Satarug, S1
Lang, MA1
Mairiang, P1
Pelkonen, P1
Bartsch, H1
Haswell-Elkins, MR1
Abdel-Hadi, AM1
Talaat, M1
Doehring-Schwerdtfeger, E1
Abdel-Rahim, IM1
Kardorff, R1
Kaiser, C1
Franke, D1
Schlake, J1
Richter, J1
Elsheikh, M1
Mohamed-Ali, Q1
Ehrich, JH1

Trials

1 trial available for praziquantel and Cirrhosis

ArticleYear
Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity twenty-three months after treatment with praziquantel.
    The American journal of tropical medicine and hygiene, 1992, Volume: 46, Issue:4

    Topics: Adolescent; Child; Feces; Fibrosis; Follow-Up Studies; Humans; Liver; Morbidity; Parasite Egg Count;

1992

Other Studies

13 other studies available for praziquantel and Cirrhosis

ArticleYear
Persistent advanced periductal fibrosis is associated with cagA-positive Helicobacter pylori infection in post-praziquantel treatment of opisthorchiasis.
    Helicobacter, 2022, Volume: 27, Issue:4

    Topics: Antigens, Bacterial; Bacterial Proteins; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Fibrosis; Fo

2022
Biochanin A in murine
    Journal of helminthology, 2023, Feb-06, Volume: 97

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents; Fibrosis; Inflammation; Liver; Mice; Oxidative Str

2023
Recombinant Sj16 protein with novel activity alleviates hepatic granulomatous inflammation and fibrosis induced by Schistosoma japonicum associated with M2 macrophages in a mouse model.
    Parasites & vectors, 2019, Sep-23, Volume: 12, Issue:1

    Topics: Animals; Anthelmintics; Disease Models, Animal; Fibrosis; Granuloma; Helminth Proteins; Immunologic

2019
Hepatobiliary morbidities detected by ultrasonography in Opisthorchis viverrini-infected patients before and after praziquantel treatment: a five-year follow up study.
    Acta tropica, 2021, Volume: 217

    Topics: Adult; Animals; Anthelmintics; Bile Ducts, Intrahepatic; Case-Control Studies; Cholangiocarcinoma; D

2021
An adjuvant effect of Metformin as an anti-fibrotic agent when administered with the anti-schistosomal Praziquantel in Schistosoma mansoni infected mice.
    Tropical biomedicine, 2021, Jun-01, Volume: 38, Issue:2

    Topics: Adjuvants, Pharmaceutic; Animals; Anthelmintics; Diabetes Mellitus, Type 2; Fibrosis; Granuloma; Mal

2021
Elevated Levels of Urinary 8-oxodG Correlate with Persistent Periductal Fibrosis after Praziquantel Treatment in Chronic Opisthorchiasis.
    The American journal of tropical medicine and hygiene, 2018, Volume: 98, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Animals; Anthelmintics; Biomarkers; Cholangiocarcinoma; Chronic

2018
Nanoencapsulated curcumin and praziquantel treatment reduces periductal fibrosis and attenuates bile canalicular abnormalities in Opisthorchis viverrini-infected hamsters.
    Nanomedicine : nanotechnology, biology, and medicine, 2016, Volume: 12, Issue:1

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Bile Canaliculi; Cricetinae; Curcum

2016
Treatment of acute schistosomiasis mansoni with praziquantel and an antifibrotic agent in mice. Maintenance of resistance to infection.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:6

    Topics: Acute Disease; Aminopropionitrile; Animals; Antiplatyhelmintic Agents; Drug Resistance; Fibrosis; Gr

2003
Asymptomatic schistosomiasis in a young Sudanese refugee.
    Australian family physician, 2007, Volume: 36, Issue:4

    Topics: Adolescent; Animals; Anthelmintics; Australia; Fibrosis; Humans; Male; Praziquantel; Refugees; Schis

2007
Schistosomal glomerulopathy: a putative role for commonly associated Salmonella infection.
    Journal of the Egyptian Society of Parasitology, 1995, Volume: 25, Issue:1

    Topics: Animals; Antibodies, Helminth; Chloramphenicol; Complement C3; Fibrosis; Glomerulonephritis; Humans;

1995
Gene expression of transforming growth factor beta 1 and extracellular matrix proteins in murine Schistosoma mansoni infection.
    Gastroenterology, 1994, Volume: 107, Issue:3

    Topics: Animals; Extracellular Matrix Proteins; Female; Fibrosis; Gene Expression; Liver; Mice; Mice, Inbred

1994
Induction of cytochrome P450 2A6 expression in humans by the carcinogenic parasite infection, opisthorchiasis viverrini.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1996, Volume: 5, Issue:10

    Topics: Analysis of Variance; Animals; Antiplatyhelmintic Agents; Aryl Hydrocarbon Hydroxylases; Bile Ducts,

1996
Histological assessment of tissue repair after treatment of human schistosomiasis.
    Acta tropica, 2000, Oct-23, Volume: 77, Issue:1

    Topics: Adult; Animals; Anthelmintics; Cricetinae; Dogs; Egypt; Fibrosis; Humans; Kidney Glomerulus; Liver;

2000