Page last updated: 2024-11-03

praziquantel and Cirrhosis, Liver

praziquantel has been researched along with Cirrhosis, Liver in 73 studies

azinox: Russian drug

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of repeated application of praziquantel in the treatment of hepatic fibrosis due to schistosomiasis."9.22[Efficacy of repeated application of praziquantel in treatment of hepatic fibrosis due to schistosomiasis]. ( Hong-Bao, L; Ming, S, 2016)
"Five hundred thirty six Sudanese schoolchildren with Schistosoma mansoni infection were treated at random with either 20 mg or 40 mg/kg praziquantel."9.07Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity seven months after treatment with praziquantel. ( Abdalla, M; Abdel-Rahim, IM; Doehring-Schwerdtfeger, E; Elsheikh, M; Franke, D; Kaiser, C; Kardorff, R; Mohamed-Ali, Q; Schafer, P; Schlake, J, 1991)
"To investigate the clinical therapeutic effect of biological information infrared liver therapeutic apparatus (BILT) combined with praziquantel in the treatment of patients with chronic schistosomiasis."7.85[Therapeutic effect of BILT combined with praziquantel in treatment of chronic schistosomiasis]. ( Hong-Bo, W; Li-le, L; Na, Z; Ni-Na, P; Ru-Yi, L; Yan, M; Yu, H, 2017)
"To study the therapeutical effect and mechanisms of resveratrol and its combination with praziquantel on the liver fibrosis due to Schistosoma japonicum infection."7.79[Therapeutic effect of resveratrol as well as resveratrol combined with praziquantel on the liver fibrosis due to Schistosoma japonicum infection in mice]. ( Chen, Y; Xiao, Z, 2013)
"Colchicine treated mice showed significant decrease in prevalence of fibrocellular and fibrocellular and fibrous granulomas in liver specimens compared to corresponding control groups."7.69Histopathological evidences for the antifibrogenic effect of colchicine in schistosomiasis mansoni in mice. ( el-Monayerhy, MS; Fahmy, IA; Montasser, MF; Rashad, MS; Sabry, NM; Younis, TA, 1994)
" The effect of treatment with praziquantel at 8, 12, and 20 weeks postinfection on fibrosis was assessed by determination of total hepatic collagen content, ratio of type III/I + III collagen, granuloma volume, and histopathological examination of liver section."7.67Effect of praziquantel on hepatic fibrosis in experimental Schistosomiasis mansoni. ( Abdallah, NM; Botros, SS; el-Badrawy, NM; Hassanein, HI; Herbage, D; Nagy, FM, 1988)
"mansoni) induced liver fibrosis."5.48Impact of treatment with a Protein Tyrosine Kinase Inhibitor (Genistein) on acute and chronic experimental Schistosoma mansoni infection. ( El-Sayed, SH; Mahmoud, SS; Negm, MSI; Raafat, A; Rizk, EMA; Sobhy, MMK, 2018)
"To evaluate the efficacy of repeated application of praziquantel in the treatment of hepatic fibrosis due to schistosomiasis."5.22[Efficacy of repeated application of praziquantel in treatment of hepatic fibrosis due to schistosomiasis]. ( Hong-Bao, L; Ming, S, 2016)
"Five hundred thirty six Sudanese schoolchildren with Schistosoma mansoni infection were treated at random with either 20 mg or 40 mg/kg praziquantel."5.07Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity seven months after treatment with praziquantel. ( Abdalla, M; Abdel-Rahim, IM; Doehring-Schwerdtfeger, E; Elsheikh, M; Franke, D; Kaiser, C; Kardorff, R; Mohamed-Ali, Q; Schafer, P; Schlake, J, 1991)
"The pharmacokinetics and therapeutic efficacy of praziquantel (Distocide; Epico, El-Asher-Men-Ramadan City, Egypt) were studied in 40 patients with schistosomiasis mansoni and various degrees of hepatic dysfunction."5.07Clinical and pharmacokinetic study of praziquantel in Egyptian schistosomiasis patients with and without liver cell failure. ( Abdel-Bary, MA; Abdel-Fatah, SA; el Guiniady, MA; el Touny, MA; Metwally, A, 1994)
"These findings suggest that in order to reverse moderate to severe liver fibrosis due to schistosomiasis and improve clinical outcomes, a higher clinical dosage of praziquantel (i."3.85Biennial versus annual treatment for schistosomiasis and its impact on liver morbidity. ( Guevarra, JR; Harn, DA; Inobaya, MT; Lam, AK; Li, Y; McManus, DP; Ng, SK; Olveda, DU; Olveda, RM; Ross, AG; Vinluan, ML, 2017)
"To investigate the clinical therapeutic effect of biological information infrared liver therapeutic apparatus (BILT) combined with praziquantel in the treatment of patients with chronic schistosomiasis."3.85[Therapeutic effect of BILT combined with praziquantel in treatment of chronic schistosomiasis]. ( Hong-Bo, W; Li-le, L; Na, Z; Ni-Na, P; Ru-Yi, L; Yan, M; Yu, H, 2017)
"To assess whether schistosomiasis coinfection with chronic hepatitis C virus (HCV) influences hepatic fibrosis and pegylated-interferon/ribavirin (PEG-IFN/RIB) therapy response."3.79Coinfection with hepatitis C virus and schistosomiasis: fibrosis and treatment response. ( Abdel-Rahman, M; El Raziky, M; El-Akel, W; El-Sayed, M; Elsharkawy, A; Esmat, G; Ghoneim, H; Khattab, H, 2013)
"To explore the value of B-ultrasound on the evaluation of the effects of traditional Chinese medicine compound of Radix astragali, Salvia miltiorrhiza and Angelica sinensis, and TCM + praziquantel on liver fibrosis in rabbits with schistosomiasis."3.79Effect of Chinese herbal compound on liver fibrosis in rabbits with schistosomiasis by B-ultrasound. ( Liang, XL; Yuan, JY, 2013)
"To study the therapeutical effect and mechanisms of resveratrol and its combination with praziquantel on the liver fibrosis due to Schistosoma japonicum infection."3.79[Therapeutic effect of resveratrol as well as resveratrol combined with praziquantel on the liver fibrosis due to Schistosoma japonicum infection in mice]. ( Chen, Y; Xiao, Z, 2013)
"To evaluate the effect of rosiglitazone in a murine model of liver fibrosis induced by Schistosoma japonicum infection."3.74Rosiglitazone prevents murine hepatic fibrosis induced by Schistosoma japonicum. ( Chen, H; He, YW; Liu, WQ; Zhang, JH, 2008)
"Colchicine treated mice showed significant decrease in prevalence of fibrocellular and fibrocellular and fibrous granulomas in liver specimens compared to corresponding control groups."3.69Histopathological evidences for the antifibrogenic effect of colchicine in schistosomiasis mansoni in mice. ( el-Monayerhy, MS; Fahmy, IA; Montasser, MF; Rashad, MS; Sabry, NM; Younis, TA, 1994)
" The effect of treatment with praziquantel at 8, 12, and 20 weeks postinfection on fibrosis was assessed by determination of total hepatic collagen content, ratio of type III/I + III collagen, granuloma volume, and histopathological examination of liver section."3.67Effect of praziquantel on hepatic fibrosis in experimental Schistosomiasis mansoni. ( Abdallah, NM; Botros, SS; el-Badrawy, NM; Hassanein, HI; Herbage, D; Nagy, FM, 1988)
"Schistosomiasis is a prevalent parasitic disease worldwide."2.61The role of microRNAs in the pathogenesis, grading and treatment of hepatic fibrosis in schistosomiasis. ( Chen, H; Chen, Q; Gong, Q; Nie, H; Zhang, J; Zheng, B; Zheng, T, 2019)
"In China, only schistosomiasis japonica is transmitted."2.52Research and control of advanced schistosomiasis japonica in China. ( Feng, A; Huang, Y; Wu, W, 2015)
"Liver fibrosis is the main cause of death in the 20 millions individuals suffering from chronic schistosomosis."2.41[Schistosoma mansoni schistosomiasis]. ( Dessein, A; Ranque, S, 2001)
"Schistosoma mansoni liver fibrosis is a complicated multicellular process involving numerous cytokines, chemokines, and growth factors."1.72Role of IL-17A in enhancing liver fibrosis induced by TGF-β1 and IL-13 in Schistosoma mansoni infected mice. ( Abd Allah, MH; Abo-Sheishaa, GA; Bayoumy, AS; Shalash, IR; Zaalouk, TK, 2022)
"Although the pathogenesis of liver fibrosis has been intensively studied, the choice of effective treatment is still inadequate."1.72Antifibrotic and anthelminthic effect of casticin on Schistosoma mansoni-infected BALB/c mice. ( Chang, KC; Cheng, PC; Lam, HYP; Lan, YC; Liang, TR; Peng, SY, 2022)
"Praziquantel not only has broad-spectrum anti-trematode and anti-tapeworm effects, but also has pharmacological effects such as regulating inflammatory response and anti-fibrosis."1.62[Progress of researches on the actions of praziquantel against hepatic fibrosis]. ( Dai, JR; Yuan, X, 2021)
"Omeprazole is a proton pump inhibitor which is reported to have antiparasitic properties."1.51Assessment of the potential therapeutic effects of omeprazole in Schistosoma mansoni infected mice. ( Abdel Ghaffar, AE; Alshenawy, HA; Elgendy, DI; Ellakany, AR, 2019)
"PZQ exhibited a strong efficacy against liver fibrosis by inhibiting activation of HSCs via Smad7 up-regulation, suggesting potential broad utility in treatment of diseases characterized by liver fibrosis."1.51Praziquantel ameliorates CCl ( Kong, D; Liu, J; Liu, X; Lu, Z; Qiu, J; Wang, Y; Xie, Y; Zhang, R; Zhou, C, 2019)
"Liver fibrosis is an important process that occurs in most types of chronic liver diseases and often results in the end stage of liver diseases, such as cirrhosis, portal hypertension, and hepatocellular carcinoma."1.48Sorafenib and praziquantel synergistically attenuate Schistosoma japonicum-induced liver fibrosis in mice. ( Chen, Y; Dong, H; Liu, X; Ma, Z; Wang, L; Xia, D; Xiong, Y, 2018)
" CONCLUSIONS Our findings suggest that the treatment using APS-1 in combination with praziquantel attenuated S."1.48A Polysaccharide from Amusium Pleuronectes Combined with Praziquantel Treatment Ameliorates Hepatic Fibrosis in Schistosoma Japonicum-Infected Mice. ( Hu, W; Jiang, Y; Lv, Y; Sun, T; Tang, X; Zhan, X; Zhang, W; Zhou, S, 2018)
"mansoni) induced liver fibrosis."1.48Impact of treatment with a Protein Tyrosine Kinase Inhibitor (Genistein) on acute and chronic experimental Schistosoma mansoni infection. ( El-Sayed, SH; Mahmoud, SS; Negm, MSI; Raafat, A; Rizk, EMA; Sobhy, MMK, 2018)
"Liver fibrosis is the main pathology of schistosomiasis and its complications are the major cause of death in infected cases."1.46Artichoke leaf extract protects liver of Schistosoma mansoni infected mice through modulation of hepatic stellate cells recruitment. ( Brakat, RM; Mohamed, ASED; Sharaf El-Deen, SA, 2017)
"Liver fibrosis was reduced significantly evidenced by reduced hydroxyproline levels [P<0."1.46Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis. ( Ashour, RH; Elhenawy, AA; Megahed, N; Nabih, N; Shalaby, NM, 2017)
"mansoni)-induced liver fibrosis in mice."1.43Sodium valproate, a histone deacetylase inhibitor, with praziquantel ameliorates Schistosoma mansoni-induced liver fibrosis in mice. ( Eissa, MM; Elatrebi, SF; Elsakkar, MG; Hewedy, WA; Nassra, RM, 2016)
"Regression of S."1.43Wharton's jelly-derived mesenchymal stem cells combined with praziquantel as a potential therapy for Schistosoma mansoni-induced liver fibrosis. ( Abdelsalam, RM; Attia, YM; El-Khatib, AS; Elkhafif, N; Elmazar, MM; Hammam, OA; Kenawy, SA; Mansour, MT, 2016)
"Schistomiasis was associated with hepatomegaly (adjusted prevalence ratio [aPR] = 1."1.42Morbidity associated with schistosomiasis before and after treatment in young children in Rusinga Island, western Kenya. ( Davis, SM; Fox, LM; Harris, R; Kareko, EI; Mulama, F; Mwinzi, PM; Ochola, E; Odiere, MR; Rawago, F; Samuels, AM; Wiegand, RE; Won, KY, 2015)
" All 8 animals were treated under anaesthesia by oral gavage with PZQ at 60 mg/kg dosing that was well tolerated."1.39Intestinal schistosomiasis in chimpanzees on Ngamba Island, Uganda: observations on liver fibrosis, schistosome genetic diversity and praziquantel treatment. ( Adriko, M; Ajarova, L; Arinaitwe, M; Betson, M; Kabatereine, NB; Mopya, S; Mugisha, L; Rukundo, J; Standley, CJ; Stothard, JR, 2013)
"Hepatic schistosomiasis is a well recognized cause of chronic liver disease and portal hypertension."1.38Incidental hepatic schistosomiasis in a liver transplant recipient. ( Ariza-Heredia, E; Razonable, RR, 2012)
"Praziquantel (PZQ) is an isoquinoline derivative (2-cyclohexylcarbonyl-1, 2, 3, 6, 7, 11b-hexahydro-4H-pyrazino{2,1-a}-isoquinoline-4-one), and is currently the drug of choice for all forms of schistosomiasis."1.38Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis. ( Ain-Shoka, AA; Badawy, AA; Ebeid, FA; El-Lakkany, NM; El-Maadawy, WH; Hammam, OA, 2012)
"Its effect on the extent of liver fibrosis, through estimation of hepatic hydroxyproline and hepatic collagen content in liver hydrolysates, was also evaluated."1.38Tranilast ameliorates impaired hepatic functions in Schistosoma mansoni-infected mice. ( Ammar, EM; Elkashef, WF; Gameil, NM; Said, E; Said, SA, 2012)
"However, PZQ does not improve liver fibrosis."1.38Therapeutic effect of alpha lipoic acid combined with praziquantel on liver fibrosis induced by Schistosoma mansoni challenged mice. ( Aabdel-Wahab, S; Abdel-Hafeez, EH; Abdulla, AM; Ahmad, AK; Mosalem, FA, 2012)
"Liver fibrosis was graded according to semi-quantitative scoring system (SSS) method."1.37[Effect of ginsenoside Rg3 on hepatic fibrosis in murine schistosomiasis japonica]. ( Jia, XM; Li, CY; Li, F; Wang, H; Zeng, J, 2011)
"Praziquantel treatment in Opisthorchis viverrini-infected patients reduces the hepatobiliary fibrosis due to tissue resorption, however, some fibroses are irreversible."1.35Effect of praziquantel treatment on the expression of matrix metalloproteinases in relation to tissue resorption during fibrosis in hamsters with acute and chronic Opisthorchis viverrini infection. ( Boonmars, T; Hiraku, Y; Pinlaor, P; Pinlaor, S; Prakobwong, S; Wongkham, C, 2009)
"Effects of PTX on the content change of hepatic TGF-beta1, type I and type III collagen in schistosomiasis japonica mice with liver fibrosis were related to the dosage of PTX, high dose PTX treated group could significantly reduce the content of TGF-beta1 (0."1.32Effects of pentoxifylline on the hepatic content of TGF-beta1 and collagen in Schistosomiasis japonica mice with liver fibrosis. ( Cai, SQ; Luo, DD; Xiong, LJ; Zen, LL; Zhu, JF, 2003)
"Liver fibrosis was mild in all HTLV-1 coinfected patients and efficacy of praziquantel was lower in patients dually infected than in patients infected only with S."1.32HTLV-1 modifies the clinical and immunological response to schistosomiasis. ( Alcantara, L; Carvalho, EM; Gonzalez, D; Gonzalez, T; Guerreiro, JB; Ho, JL; Neva, F; Passos, J; Porto, AF; Santos, SB, 2004)
"Schistosomiasis mansoni is a tropical helminthic disease characterized by parasite egg-induced granulomatous inflammation and cumulative fibrosis."1.32Expression of matrix metalloproteinases and their inhibitors during the resorption of schistosome egg-induced fibrosis in praziquantel-treated mice. ( Boros, DL; Gerard, HC; Hudson, AP; Singh, KP, 2004)

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-19905 (6.85)18.7374
1990's11 (15.07)18.2507
2000's12 (16.44)29.6817
2010's39 (53.42)24.3611
2020's6 (8.22)2.80

Authors

AuthorsStudies
Yuan, X1
Dai, JR1
Abou Rayia, DM1
Ashour, DS1
Abo Safia, HS1
Abdel Ghafar, MT1
Amer, RS1
Saad, AE1
Abd Allah, MH1
Zaalouk, TK1
Abo-Sheishaa, GA1
Shalash, IR1
Bayoumy, AS1
Dong, H3
Zhao, L2
Sun, H2
Shang, M2
Lv, G2
Yu, X2
Hu, B2
Huang, Y3
Liu, J1
Kong, D1
Qiu, J1
Xie, Y1
Lu, Z1
Zhou, C2
Liu, X2
Zhang, R1
Wang, Y2
Mueller, A1
Fuss, A1
Ziegler, U1
Kaatano, GM1
Mazigo, HD1
Ellakany, AR1
Elgendy, DI1
Alshenawy, HA1
Abdel Ghaffar, AE1
Chen, Q1
Zhang, J1
Zheng, T1
Chen, H2
Nie, H1
Zheng, B1
Gong, Q1
Nono, JK1
Fu, K1
Mpotje, T1
Varrone, G1
Aziz, NA1
Mosala, P1
Hlaka, L1
Kamdem, SD1
Xu, D1
Spangenberg, T1
Brombacher, F1
Lam, HYP1
Liang, TR1
Lan, YC1
Chang, KC1
Cheng, PC1
Peng, SY1
Elhenawy, AA1
Ashour, RH1
Nabih, N1
Shalaby, NM1
Megahed, N1
Sharaf El-Deen, SA1
Brakat, RM1
Mohamed, ASED1
Sanchez, MC1
Krasnec, KV1
Parra, AS1
von Cabanlong, C1
Gobert, GN1
Umylny, B1
Cupit, PM1
Cunningham, C1
Abd El-Aal, NF1
Hamza, RS1
Harb, O1
Sobhy, MMK1
Mahmoud, SS2
El-Sayed, SH1
Rizk, EMA1
Raafat, A1
Negm, MSI1
Hong-Bao, L1
Ming, S1
Ru-Yi, L1
Na, Z1
Ni-Na, P1
Li-le, L1
Yu, H1
Yan, M1
Hong-Bo, W1
Tang, X1
Hu, W1
Lv, Y1
Zhang, W1
Sun, T1
Jiang, Y1
Zhan, X1
Zhou, S1
Wangboon, C1
Yongvanit, P1
Loilome, W1
Thanan, R1
Worasith, C1
Eamudomkarn, C1
Chamadol, N1
Mairiang, E1
Sithithaworn, J1
Saichua, P1
Sripa, B1
Khuntikeo, N1
Bethony, JM1
Sithithaworn, P1
Ma, Z1
Xia, D1
Wang, L1
Chen, Y2
Xiong, Y1
Issa, YA1
El Achy, SN1
Mady, RF1
Abdel-Rahman, M1
El-Sayed, M1
El Raziky, M1
Elsharkawy, A1
El-Akel, W1
Ghoneim, H1
Khattab, H1
Esmat, G1
Liang, XL1
Yuan, JY1
Attia, YM2
Elalkamy, EF1
Hammam, OA3
El-Khatib, AS2
Xiao, Z1
Wu, W1
Feng, A1
Davis, SM1
Wiegand, RE1
Mulama, F1
Kareko, EI1
Harris, R1
Ochola, E1
Samuels, AM1
Rawago, F1
Mwinzi, PM1
Fox, LM1
Odiere, MR1
Won, KY1
Schacherer, D1
Birkenfeld, G1
Gassiep, I1
Clark, PJ1
McManus, DP3
Looke, DL1
Elkhafif, N1
Mansour, MT1
Elmazar, MM1
Abdelsalam, RM1
Kenawy, SA1
Elsakkar, MG1
Eissa, MM1
Hewedy, WA1
Nassra, RM1
Elatrebi, SF1
Olveda, DU2
Inobaya, MT1
Olveda, RM3
Vinluan, ML2
Ng, SK2
Harn, DA2
Li, Y2
Guevarra, JR2
Lam, AK2
Ross, AG2
Inobaya, M1
Weerakoon, K1
Ramm, GA1
Pinlaor, S1
Prakobwong, S1
Boonmars, T1
Wongkham, C1
Pinlaor, P1
Hiraku, Y1
Barros, LA1
Costa-Silva, M1
Biolchini, CL1
Neves, RH1
Machado-Silva, JR1
Rahoud, SA1
Mergani, A1
Khamis, AH1
Saeed, OK1
Mohamed-Ali, Q2
Dessein, AJ1
Elwali, NE1
Fabre, V1
Wu, H1
PondTor, S1
Coutinho, H1
Acosta, L1
Jiz, M1
Olveda, R1
Cheng, L1
White, ES1
Jarilla, B1
McGarvey, ST2
Friedman, JF1
Kurtis, JD1
Ariza-Heredia, E1
Razonable, RR1
Liang, YJ1
Luo, J1
Yuan, Q1
Zheng, D1
Liu, YP1
Shi, L1
Zhou, Y1
Chen, AL1
Ren, YY1
Sun, KY1
Sun, Y1
Zhang, ZS1
Zeng, J1
Wang, H1
Jia, XM1
Li, CY1
Li, F1
Abdel Fattah, NS1
Ahmed, NS1
El-Lakkany, NM1
El-Maadawy, WH1
Badawy, AA1
Ain-Shoka, AA1
Ebeid, FA1
Said, E1
Said, SA1
Elkashef, WF1
Gameil, NM1
Ammar, EM1
Chen, BL1
Zhang, GY1
Wang, SP1
Li, Q1
Xu, MH1
Shen, YM1
Yan, L1
Gu, H1
Li, J1
Huang, YL1
Mu, YB1
Abdel-Hafeez, EH1
Ahmad, AK1
Abdulla, AM1
Aabdel-Wahab, S1
Mosalem, FA1
Xu, H2
Qian, H1
Zhu, W1
Zhang, X1
Yan, Y1
Mao, F1
Wang, M1
Xu, W1
Standley, CJ1
Mugisha, L1
Adriko, M1
Arinaitwe, M1
Rukundo, J1
Ajarova, L1
Mopya, S1
Betson, M1
Kabatereine, NB2
Stothard, JR1
Xiong, LJ1
Zhu, JF1
Luo, DD1
Zen, LL1
Cai, SQ1
Yan, SN1
Fang, H1
Xiang, LK1
Singh, KP1
Gerard, HC1
Hudson, AP1
Boros, DL1
Porto, AF1
Santos, SB1
Alcantara, L1
Guerreiro, JB1
Passos, J1
Gonzalez, T1
Neva, F1
Gonzalez, D1
Ho, JL1
Carvalho, EM1
Dunne, DW1
Vennervald, BJ1
Booth, M1
Joseph, S1
Fitzsimmons, CM1
Cahen, P1
Sturrock, RF1
Ouma, JH1
Mwatha, JK1
Kimani, G1
Kariuki, HC1
Kazibwe, F1
Tukahebwa, E1
Hrckova, G1
Velebný, S1
Daxnerová, Z1
Solár, P1
Andrade, ZA1
Baptista, AP1
Santana, TS1
Berhe, N1
Myrvang, B1
Gundersen, SG1
He, YW1
Liu, WQ1
Zhang, JH1
Yang, YQ1
Zhu, XY1
Yang, HZ1
Le, WJ1
el Guiniady, MA1
el Touny, MA1
Abdel-Bary, MA1
Abdel-Fatah, SA1
Metwally, A1
Wiest, PM1
Wu, G1
Zhong, S1
Yuan, J1
Peters, PA1
Olds, GR1
Montasser, MF1
Younis, TA1
Fahmy, IA1
Sabry, NM1
el-Monayerhy, MS1
Rashad, MS1
Morris, W1
Knauer, CM1
Mansy, SS1
Yehia, HA1
Hassan, MM1
Hassan, EA1
Youssef, MM1
Hadi, AA1
Mackenzie, CD1
Cai, W1
Chen, Z1
Chen, F1
Liu, R1
Wang, J1
Ricard-Blum, S1
Hartmann, DJ1
Grenard, P1
Ravaoalimalala, VE1
Boisier, P1
Esterre, P1
Ranque, S1
Dessein, A1
Cheever, AW1
Macedonia, JG1
Deb, S1
Cheever, EA1
Mosimann, JE1
Tanaka, M1
Doehring-Schwerdtfeger, E1
Abdel-Rahim, IM1
Schlake, J1
Kardorff, R1
Franke, D1
Kaiser, C1
Elsheikh, M1
Abdalla, M1
Schafer, P1
Homeida, MA2
el Tom, I2
Nash, T2
Bennett, JL3
Fenwick, A1
DeFalla, AA1
Suliman, S1
Kardaman, MW1
el-Badrawy, NM1
Hassanein, HI1
Botros, SS1
Nagy, FM1
Abdallah, NM1
Herbage, D1
Homeida, MM1
el Tom, IA1
Sulaiman, SM1
Daffalla, AA1
el-Hawy, AM1
Anter, A1
Hegazi, MM1
Massoud, A1
Abou Tal, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study on the Role of Antioxidant Micronutrients on the Reversal of Schistosomal Peri-portal Fibrosis of the Liver.[NCT01260012]414 participants (Anticipated)Interventional2010-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for praziquantel and Cirrhosis, Liver

ArticleYear
The role of microRNAs in the pathogenesis, grading and treatment of hepatic fibrosis in schistosomiasis.
    Parasites & vectors, 2019, Dec-30, Volume: 12, Issue:1

    Topics: Animals; Anthelmintics; Humans; Liver Cirrhosis; MicroRNAs; Praziquantel; Schistosoma; Schistosomias

2019
Research and control of advanced schistosomiasis japonica in China.
    Parasitology research, 2015, Volume: 114, Issue:1

    Topics: Animals; Anthelmintics; China; Humans; Liver Cirrhosis; Praziquantel; Schistosoma japonicum; Schisto

2015
Cardiopulmonary manifestations of schistosomiasis.
    Seminars in respiratory infections, 1997, Volume: 12, Issue:2

    Topics: Antiplatyhelmintic Agents; Heart Diseases; Humans; Hypertension, Portal; Liver Cirrhosis; Lung Disea

1997
[Schistosoma mansoni schistosomiasis].
    La Revue du praticien, 2001, Dec-01, Volume: 51, Issue:19

    Topics: Cause of Death; Chronic Disease; Genetic Predisposition to Disease; Humans; Immunity, Innate; Liver

2001
Mini-review: the ultrasonographical and serological changes and their improvement after praziquantel treatment in Schistosoma japonicum infected patients in Leyte, Philippines.
    Memorias do Instituto Oswaldo Cruz, 1992, Volume: 87 Suppl 4

    Topics: Adolescent; Adult; Atrophy; Bile Acids and Salts; Biomarkers; Humans; Hypertrophy; Liver; Liver Cirr

1992

Trials

3 trials available for praziquantel and Cirrhosis, Liver

ArticleYear
[Efficacy of repeated application of praziquantel in treatment of hepatic fibrosis due to schistosomiasis].
    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control, 2016, Oct-09, Volume: 29, Issue:2

    Topics: Humans; Liver; Liver Cirrhosis; Praziquantel; Schistosomiasis

2016
Clinical and pharmacokinetic study of praziquantel in Egyptian schistosomiasis patients with and without liver cell failure.
    The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:6

    Topics: Absorption; Adolescent; Adult; Bilirubin; Female; Hepatomegaly; Humans; Linear Models; Liver; Liver

1994
Ultrasonographical investigation of periportal fibrosis in children with Schistosoma mansoni infection: reversibility of morbidity seven months after treatment with praziquantel.
    The American journal of tropical medicine and hygiene, 1991, Volume: 44, Issue:4

    Topics: Child; Hepatomegaly; Humans; Liver; Liver Cirrhosis; Parasite Egg Count; Praziquantel; Random Alloca

1991

Other Studies

65 other studies available for praziquantel and Cirrhosis, Liver

ArticleYear
[Progress of researches on the actions of praziquantel against hepatic fibrosis].
    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control, 2021, Mar-30, Volume: 33, Issue:5

    Topics: Humans; Liver Cirrhosis; Praziquantel

2021
Human umbilical cord blood mesenchymal stem cells as a potential therapy for schistosomal hepatic fibrosis: an experimental study.
    Pathogens and global health, 2023, Volume: 117, Issue:2

    Topics: Animals; Fetal Blood; Humans; Liver Cirrhosis; Mesenchymal Stem Cells; Mice; Praziquantel

2023
Role of IL-17A in enhancing liver fibrosis induced by TGF-β1 and IL-13 in Schistosoma mansoni infected mice.
    The Egyptian journal of immunology, 2022, Volume: 29, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Case-Control Studies; Cytokines; Eosine Yellowish-(YS); Female; Hem

2022
Coinfection of Clonorchis sinensis and hepatitis B virus: clinical liver indices and interaction in hepatic cell models.
    Parasites & vectors, 2022, Dec-12, Volume: 15, Issue:1

    Topics: Adult; Animals; Clonorchis sinensis; Coinfection; Hepatitis B; Hepatitis B virus; Hepatocytes; Human

2022
Coinfection of Clonorchis sinensis and hepatitis B virus: clinical liver indices and interaction in hepatic cell models.
    Parasites & vectors, 2022, Dec-12, Volume: 15, Issue:1

    Topics: Adult; Animals; Clonorchis sinensis; Coinfection; Hepatitis B; Hepatitis B virus; Hepatocytes; Human

2022
Coinfection of Clonorchis sinensis and hepatitis B virus: clinical liver indices and interaction in hepatic cell models.
    Parasites & vectors, 2022, Dec-12, Volume: 15, Issue:1

    Topics: Adult; Animals; Clonorchis sinensis; Coinfection; Hepatitis B; Hepatitis B virus; Hepatocytes; Human

2022
Coinfection of Clonorchis sinensis and hepatitis B virus: clinical liver indices and interaction in hepatic cell models.
    Parasites & vectors, 2022, Dec-12, Volume: 15, Issue:1

    Topics: Adult; Animals; Clonorchis sinensis; Coinfection; Hepatitis B; Hepatitis B virus; Hepatocytes; Human

2022
Praziquantel ameliorates CCl
    British journal of pharmacology, 2019, Volume: 176, Issue:24

    Topics: Animals; Carbon Tetrachloride; Cell Line; Disease Models, Animal; Gene Expression; Hepatic Stellate

2019
Intestinal schistosomiasis of Ijinga Island, north-western Tanzania: prevalence, intensity of infection, hepatosplenic morbidities and their associated factors.
    BMC infectious diseases, 2019, Oct-07, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anthelmintics; Child; Child, Preschool; Cross-S

2019
Assessment of the potential therapeutic effects of omeprazole in Schistosoma mansoni infected mice.
    Parasitology research, 2019, Volume: 118, Issue:12

    Topics: Animals; Drug Therapy, Combination; Granuloma; Liver Cirrhosis; Male; Mice; Omeprazole; Parasite Egg

2019
Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in in vitro and in vivo preclinical models.
    Scientific reports, 2020, 06-30, Volume: 10, Issue:1

    Topics: Animals; Antiparasitic Agents; Female; Hepatic Stellate Cells; Hepatocytes; Kupffer Cells; Liver Cir

2020
Antifibrotic and anthelminthic effect of casticin on Schistosoma mansoni-infected BALB/c mice.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2022, Volume: 55, Issue:2

    Topics: Animals; Anthelmintics; Anti-Infective Agents; Flavonoids; Humans; Liver; Liver Cirrhosis; Mice; Mic

2022
Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis.
    Parasitology international, 2017, Volume: 66, Issue:5

    Topics: Anilides; Animals; Cercaria; Disease Models, Animal; Drug Therapy, Combination; Egypt; Female; Hedge

2017
Artichoke leaf extract protects liver of Schistosoma mansoni infected mice through modulation of hepatic stellate cells recruitment.
    Experimental parasitology, 2017, Volume: 178

    Topics: Alanine Transaminase; Animals; Anthelmintics; Aspartate Aminotransferases; Cynara scolymus; Female;

2017
Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:6

    Topics: Animals; Anthelmintics; ATP-Binding Cassette Transporters; Disease Models, Animal; Drug Resistance;

2017
Paeoniflorin targets apoptosis and ameliorates fibrosis in murine schistosomiasis mansoni: A novel insight.
    Experimental parasitology, 2017, Volume: 183

    Topics: Actins; Animals; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Biomphalaria; Fe

2017
Impact of treatment with a Protein Tyrosine Kinase Inhibitor (Genistein) on acute and chronic experimental Schistosoma mansoni infection.
    Experimental parasitology, 2018, Volume: 185

    Topics: Acute Disease; Animals; Anthelmintics; Biomphalaria; Chronic Disease; Collagen; Female; Genistein; G

2018
[Therapeutic effect of BILT combined with praziquantel in treatment of chronic schistosomiasis].
    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control, 2017, May-17, Volume: 29, Issue:5

    Topics: Case-Control Studies; Humans; Infrared Rays; Liver Cirrhosis; Praziquantel; Schistosomiasis

2017
A Polysaccharide from Amusium Pleuronectes Combined with Praziquantel Treatment Ameliorates Hepatic Fibrosis in Schistosoma Japonicum-Infected Mice.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Mar-18, Volume: 24

    Topics: Animals; Bivalvia; Cytokines; Hyaluronoglucosaminidase; Interleukin-13; Liver Cirrhosis; Male; Mice,

2018
Elevated Levels of Urinary 8-oxodG Correlate with Persistent Periductal Fibrosis after Praziquantel Treatment in Chronic Opisthorchiasis.
    The American journal of tropical medicine and hygiene, 2018, Volume: 98, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Animals; Anthelmintics; Biomarkers; Cholangiocarcinoma; Chronic

2018
Sorafenib and praziquantel synergistically attenuate Schistosoma japonicum-induced liver fibrosis in mice.
    Parasitology research, 2018, Volume: 117, Issue:9

    Topics: Actins; Animals; Collagen Type I; Collagen Type III; Female; Liver; Liver Cirrhosis; Mice; Mice, Inb

2018
Cannabinoid receptor-1 antagonism: a new perspective on treating a murine schistosomal liver fibrosis model.
    Memorias do Instituto Oswaldo Cruz, 2019, Volume: 114

    Topics: Actins; Animals; Anthelmintics; Cannabinoid Receptor Antagonists; Drug Therapy, Combination; Granulo

2019
Coinfection with hepatitis C virus and schistosomiasis: fibrosis and treatment response.
    World journal of gastroenterology, 2013, May-07, Volume: 19, Issue:17

    Topics: Adult; Antiviral Agents; Chi-Square Distribution; Coinfection; Drug Therapy, Combination; Egypt; Fem

2013
Effect of Chinese herbal compound on liver fibrosis in rabbits with schistosomiasis by B-ultrasound.
    Asian Pacific journal of tropical medicine, 2013, Volume: 6, Issue:8

    Topics: Angelica sinensis; Animals; Anthelmintics; Disease Models, Animal; Herbal Medicine; Liver; Liver Cir

2013
Telmisartan, an AT1 receptor blocker and a PPAR gamma activator, alleviates liver fibrosis induced experimentally by Schistosoma mansoni infection.
    Parasites & vectors, 2013, Jul-05, Volume: 6

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anthelmintics; Benzimidazoles; Benzoates; Disease

2013
[Therapeutic effect of resveratrol as well as resveratrol combined with praziquantel on the liver fibrosis due to Schistosoma japonicum infection in mice].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2013, Volume: 31, Issue:5

    Topics: Animals; Drug Therapy, Combination; Female; Liver Cirrhosis; Male; Mice; Oxidative Stress; Praziquan

2013
Morbidity associated with schistosomiasis before and after treatment in young children in Rusinga Island, western Kenya.
    The American journal of tropical medicine and hygiene, 2015, Volume: 92, Issue:5

    Topics: Age Distribution; Animals; Anthelmintics; Child; Child, Preschool; Cohort Studies; Cross-Sectional S

2015
A Case Report--Sonomorphological Changes in Hepatosplenic Schistosomiasis.
    Ultraschall in der Medizin (Stuttgart, Germany : 1980), 2015, Volume: 36, Issue:3

    Topics: Adult; Developing Countries; Ethiopia; Germany; Humans; Hypertension, Portal; Liver; Liver Cirrhosis

2015
Hepatobiliary and Pancreatic: Acute hepatitis in the setting of chronic Schistosoma mansoni infection and post-praziquantel therapy.
    Journal of gastroenterology and hepatology, 2016, Volume: 31, Issue:5

    Topics: Acute Disease; Animals; Anthelmintics; Anti-Inflammatory Agents; Biopsy; Chronic Disease; Hepatitis;

2016
Wharton's jelly-derived mesenchymal stem cells combined with praziquantel as a potential therapy for Schistosoma mansoni-induced liver fibrosis.
    Scientific reports, 2016, Feb-15, Volume: 6

    Topics: Animals; Cell- and Tissue-Based Therapy; Humans; Liver Cirrhosis; Mesenchymal Stem Cell Transplantat

2016
Sodium valproate, a histone deacetylase inhibitor, with praziquantel ameliorates Schistosoma mansoni-induced liver fibrosis in mice.
    Life sciences, 2016, Oct-01, Volume: 162

    Topics: Animals; Anthelmintics; Histone Deacetylase Inhibitors; Liver Cirrhosis; Male; Mice; Praziquantel; S

2016
Biennial versus annual treatment for schistosomiasis and its impact on liver morbidity.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2017, Volume: 54

    Topics: Adolescent; Adult; Aged; Animals; Child; Child, Preschool; Drug Administration Schedule; Female; Hum

2017
Diagnosing schistosomiasis-induced liver morbidity: implications for global control.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2017, Volume: 54

    Topics: Adolescent; Adult; Aged; Biomarkers; Child; Child, Preschool; Female; Humans; Hyaluronic Acid; Liver

2017
Effect of praziquantel treatment on the expression of matrix metalloproteinases in relation to tissue resorption during fibrosis in hamsters with acute and chronic Opisthorchis viverrini infection.
    Acta tropica, 2009, Volume: 111, Issue:2

    Topics: Animals; Collagen; Cricetinae; Gene Expression Profiling; Hydroxyproline; Liver; Liver Cirrhosis; Ma

2009
Effect of praziquantel administration on hepatic stereology of mice infected with Schistosoma mansoni and fed a low-protein diet.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2009, Volume: 42, Issue:9

    Topics: Animals; Anthelmintics; Diet, Protein-Restricted; Female; Hepatocytes; Liver; Liver Cirrhosis; Mice;

2009
Factors controlling the effect of praziquantel on liver fibrosis in Schistosoma mansoni-infected patients.
    FEMS immunology and medical microbiology, 2010, Volume: 58, Issue:1

    Topics: Adolescent; Adult; Age Factors; Animals; Anthelmintics; Child; Child, Preschool; Disease Progression

2010
Tissue inhibitor of matrix-metalloprotease-1 predicts risk of hepatic fibrosis in human Schistosoma japonicum infection.
    The Journal of infectious diseases, 2011, Mar-01, Volume: 203, Issue:5

    Topics: Adolescent; Adult; Animals; Anthelmintics; Biomarkers; Child; Cohort Studies; Collagen; Feces; Femal

2011
Incidental hepatic schistosomiasis in a liver transplant recipient.
    Transplant infectious disease : an official journal of the Transplantation Society, 2012, Volume: 14, Issue:1

    Topics: Animals; Anthelmintics; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Liver Diseases, Parasi

2012
New insight into the antifibrotic effects of praziquantel on mice in infection with Schistosoma japonicum.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Alanine Transaminase; Animals; Anthelmintics; Aspartate Aminotransferases; Cells, Cultured; Female;

2011
[Effect of ginsenoside Rg3 on hepatic fibrosis in murine schistosomiasis japonica].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2011, Apr-30, Volume: 29, Issue:2

    Topics: Animals; Ginsenosides; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Phytotherapy; Praziquan

2011
Evidence of intra-hepatic vascular proliferation remodeling early after cure in experimental schistosomiasis mansoni: an immunohistochemical descriptive study.
    Experimental parasitology, 2012, Volume: 130, Issue:1

    Topics: Animals; Anthelmintics; Female; Immunohistochemistry; Liver; Liver Cirrhosis; Mice; Neovascularizati

2012
Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis.
    Parasites & vectors, 2012, Jan-11, Volume: 5

    Topics: Animals; Drug Therapy, Combination; Hydroxyproline; Liver; Liver Cirrhosis; Liver Function Tests; Ma

2012
Tranilast ameliorates impaired hepatic functions in Schistosoma mansoni-infected mice.
    Inflammopharmacology, 2012, Volume: 20, Issue:2

    Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Therapy, Combination; Liver Cirrhosis; Liver Di

2012
The combined treatment of praziquantel with osteopontin immunoneutralization reduces liver damage in Schistosoma japonicum-infected mice.
    Parasitology, 2012, Volume: 139, Issue:4

    Topics: Animals; Antibodies, Neutralizing; Arteriosclerosis; Drug Therapy, Combination; Female; Granuloma; I

2012
Therapeutic effect of alpha lipoic acid combined with praziquantel on liver fibrosis induced by Schistosoma mansoni challenged mice.
    Parasitology research, 2012, Volume: 111, Issue:2

    Topics: Animals; Anthelmintics; Antioxidants; Drug Therapy, Combination; Liver Cirrhosis; Male; Mice; Mice,

2012
Mesenchymal stem cells relieve fibrosis of Schistosoma japonicum-induced mouse liver injury.
    Experimental biology and medicine (Maywood, N.J.), 2012, Volume: 237, Issue:5

    Topics: Actins; Animals; Collagen Type III; Combined Modality Therapy; Epithelial-Mesenchymal Transition; Fe

2012
Intestinal schistosomiasis in chimpanzees on Ngamba Island, Uganda: observations on liver fibrosis, schistosome genetic diversity and praziquantel treatment.
    Parasitology, 2013, Volume: 140, Issue:3

    Topics: Animals; Anthelmintics; Ape Diseases; DNA Barcoding, Taxonomic; Feces; Female; Genetic Variation; Hu

2013
Effects of pentoxifylline on the hepatic content of TGF-beta1 and collagen in Schistosomiasis japonica mice with liver fibrosis.
    World journal of gastroenterology, 2003, Volume: 9, Issue:1

    Topics: Animals; Anthelmintics; Collagen Type I; Collagen Type III; Female; Liver; Liver Cirrhosis; Mice; Pe

2003
[Detection of serum transforming growth factor beta 1 in diagnosis of hepatic fibrosis in schistosomiasis and evaluation of treatment efficacy].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2003, Volume: 21, Issue:3

    Topics: Anthelmintics; Humans; Liver Cirrhosis; Praziquantel; Schistosomiasis; Transforming Growth Factor be

2003
Expression of matrix metalloproteinases and their inhibitors during the resorption of schistosome egg-induced fibrosis in praziquantel-treated mice.
    Immunology, 2004, Volume: 111, Issue:3

    Topics: Animals; Anthelmintics; Body Weight; Cell Count; Cells, Cultured; Collagen; Cytokines; Female; Gene

2004
HTLV-1 modifies the clinical and immunological response to schistosomiasis.
    Clinical and experimental immunology, 2004, Volume: 137, Issue:2

    Topics: Adult; Animals; Anthelmintics; Antigens, Helminth; Cells, Cultured; Female; HTLV-I Infections; Human

2004
Applied and basic research on the epidemiology, morbidity, and immunology of schistosomiasis in fishing communities on Lake Albert, Uganda.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, Volume: 100, Issue:3

    Topics: Animals; Anthelmintics; Cohort Studies; Drug Resistance; Female; Fisheries; Fresh Water; Humans; Liv

2006
Praziquantel and liposomized glucan-treatment modulated liver fibrogenesis and mastocytosis in mice infected with Mesocestoides vogae (M. corti, Cestoda) tetrathyridia.
    Parasitology, 2006, Volume: 132, Issue:Pt 4

    Topics: Animals; Anthelmintics; beta-Glucans; Bromodeoxyuridine; Cestode Infections; Collagen; Drug Therapy,

2006
Remodeling of hepatic vascular changes after specific chemotherapy of schistosomal periportal fibrosis.
    Memorias do Instituto Oswaldo Cruz, 2006, Volume: 101 Suppl 1

    Topics: Animals; Anthelmintics; Chronic Disease; Disease Models, Animal; Female; Granuloma; Humans; Liver Ci

2006
Reversibility of schistosomal periportal thickening/fibrosis after praziquantel therapy: a twenty-six month follow-up study in Ethiopia.
    The American journal of tropical medicine and hygiene, 2008, Volume: 78, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Anthelmintics; Antibodies, Viral; Child; Ethiopia; Feces; Female;

2008
Rosiglitazone prevents murine hepatic fibrosis induced by Schistosoma japonicum.
    World journal of gastroenterology, 2008, May-14, Volume: 14, Issue:18

    Topics: Actins; Animals; Anthelmintics; Collagen Type I; Collagen Type III; Disease Models, Animal; Hypoglyc

2008
[Evaluation of praziquantel on rabbit liver cirrhosis due to schistosomiasis according to pathological changes (author's transl)].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1982, Volume: 4, Issue:1

    Topics: Animals; Hepatic Artery; Isoquinolines; Liver Cirrhosis; Praziquantel; Rabbits; Radiography; Schisto

1982
Impact of annual screening and chemotherapy with praziquantel on schistosomiasis japonica on Jishan Island, People's Republic of China.
    The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:2

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; China; Cohort Studies; Feces; Female; Hepat

1994
Histopathological evidences for the antifibrogenic effect of colchicine in schistosomiasis mansoni in mice.
    Journal of the Egyptian Society of Parasitology, 1994, Volume: 24, Issue:1

    Topics: Animals; Colchicine; Drug Therapy, Combination; Granuloma; Liver; Liver Cirrhosis; Mice; Praziquante

1994
Octreotide decreases connective tissue formation and improves vascular changes associated with hepatic schistosomiasis.
    Journal of the Egyptian Society of Parasitology, 1998, Volume: 28, Issue:1

    Topics: Animals; Drug Therapy, Combination; Egypt; Female; Liver Cirrhosis; Liver Diseases, Parasitic; Mice;

1998
Changes of ultrasonography and two serum biochemical indices for hepatic fibrosis in schistosomiasis japonica patients one year after praziquantel treatment.
    Chinese medical journal, 1997, Volume: 110, Issue:10

    Topics: Adolescent; Adult; Antiplatyhelmintic Agents; Biomarkers; Child; Female; Humans; Hyaluronic Acid; Li

1997
Relationships between several markers of extracellular matrix turn-over and ultrasonography in human Schistosomiasis mansoni.
    The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:4

    Topics: Amino Acids; Biomarkers; Collagen; E-Selectin; Extracellular Matrix; Humans; Hyaluronic Acid; Interc

1999
Persistence of eggs and hepatic fibrosis after treatment of Schistosoma mansoni-infected mice.
    The American journal of tropical medicine and hygiene, 1992, Volume: 46, Issue:6

    Topics: Analysis of Variance; Animals; Benzenesulfonates; Collagen; Diphenylamine; Feces; Intestines; Isothi

1992
Association of the therapeutic activity of praziquantel with the reversal of Symmers' fibrosis induced by Schistosoma mansoni.
    The American journal of tropical medicine and hygiene, 1991, Volume: 45, Issue:3

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Female; Hepatomegaly; Humans; Liver Cirrhos

1991
Effect of antischistosomal chemotherapy on prevalence of Symmers' periportal fibrosis in Sudanese villages.
    Lancet (London, England), 1988, Aug-20, Volume: 2, Issue:8608

    Topics: Adolescent; Adult; Aged; Child; Epidemiologic Methods; Humans; Liver Cirrhosis; Middle Aged; Praziqu

1988
Effect of praziquantel on hepatic fibrosis in experimental Schistosomiasis mansoni.
    Experimental and molecular pathology, 1988, Volume: 49, Issue:2

    Topics: Animals; Collagen; Electrophoresis, Polyacrylamide Gel; Granuloma; Liver; Liver Cirrhosis; Male; Mic

1988
Efficacy and tolerance of praziquantel in patients with Schistosoma mansoni infection and Symmers' fibrosis: a field study in the Sudan.
    The American journal of tropical medicine and hygiene, 1988, Volume: 38, Issue:3

    Topics: Drug Tolerance; Gallbladder; Humans; Liver Cirrhosis; Portal Vein; Praziquantel; Schistosomiasis man

1988
Polymorphonuclear leucocyte phagocytosis in bilharzial and non bilharzial patients with enteric fevers.
    Journal of the Egyptian Society of Parasitology, 1985, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Ampicillin; Chloramphenicol; Female; Humans; Liver Cirrhosis; Male; Middle Aged;

1985