Page last updated: 2024-11-03

praziquantel and Central Nervous System Cysticercosis

praziquantel has been researched along with Central Nervous System Cysticercosis in 103 studies

azinox: Russian drug

Research Excerpts

ExcerptRelevanceReference
"Our study demonstrates the safety and efficacy of albendazole and praziquantel in combination for complete radiologic resolution in children with persistent neurocysticercosis when compared with albendazole monotherapy or placebo."9.51Efficacy of Combination Therapy of Albendazole and Praziquantel vs Albendazole Monotherapy in Children With Persistent Neurocysticercosis: A Randomized Controlled Trial. ( Khandelwal, N; Saini, AG; Singh, K; Singhi, P, 2022)
"In this double-blind, placebo-controlled, phase 3 trial, patients with viable intraparenchymal neurocysticercosis were randomly assigned to receive 10 days of combined albendazole (15 mg/kg per day) plus praziquantel (50 mg/kg per day), standard albendazole (15 mg/kg per day), or increased dose albendazole (22·5 mg/kg per day)."9.19Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial. ( Bustos, JA; Escalante, D; Garcia, HH; Gavidia, M; Gonzales, I; Lescano, AG; Najar, E; Pretell, EJ; Rodriguez, L; Saavedra, H; Umeres, H; Zimic, M, 2014)
"To evaluate the efficacy and safety of a combination of albendazole and praziquantel in children with seizures and single small enhancing computerized tomographic lesions."9.14Combination therapy with albendazole and praziquantel versus albendazole alone in children with seizures and single lesion neurocysticercosis: a randomized, placebo-controlled double blind trial. ( Kaur, S; Khandelwal, N; Singhi, P; Singhi, S, 2009)
"A recently described one-day regimen of praziquantel (PZQ) therapy for neurocysticercosis (NCC), three doses of 25 mg/k given at 2 h intervals, was applied in eight patients with viable NCC cysts without any evidence of inflammation."9.09Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions. ( García, HH; Gilman, RH; Martinez, M; Pretell, EJ; Saavedra, H, 2001)
"A critical review of the available data from comparative trials suggests that albendazole is more effective than praziquantel regarding clinically important outcomes in patients with neurocysticercosis."8.84Albendazole versus praziquantel in the treatment of neurocysticercosis: a meta-analysis of comparative trials. ( Adamidi, ES; Falagas, ME; Matthaiou, DK; Panos, G, 2008)
"The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal."7.91Albendazole Sulfoxide Plasma Levels and Efficacy of Antiparasitic Treatment in Patients With Parenchymal Neurocysticercosis. ( Arroyo, G; Bonato, PS; Bustos, JA; Garcia, HH; Gilman, RH; Gonzales, I; Gonzalez, AE; Horton, J; Lanchote, VL; Lescano, AG; Pretell, EJ; Rodriguez, S; Saavedra, H; Takayanagui, OM, 2019)
" We report a case in which treatment with high-dose praziquantel resulted in prolonged perilesional edema requiring use of corticosteroids and corticosteroid-sparing agents for >1 year, suggesting a role for methotrexate in the management of this condition."7.72Prolonged perilesional edema after treatment of parenchymal neurocysticercosis: methotrexate as a corticosteroid-sparing agent. ( Keiser, PB; Nash, TE, 2003)
"Albendazole (ABZ) has been used together with praziquantel (PZQ) before for geohelminths, echinococcosis and cysticercosis, but their combined use is not yet formally recommended and only scarce, discrepant data exist on their pharmacokinetics when given together."6.76Pharmacokinetics of combined treatment with praziquantel and albendazole in neurocysticercosis. ( Bonato, PS; Bustos, JA; Garcia, HH; Gilman, RH; Gonzales, I; Gonzalez, AE; Horton, J; Lanchote, VL; Lescano, AG; Pretell, EJ; Saavedra, H; Takayanagui, OM, 2011)
"55%; P = 0."6.43Meta-analysis: Cysticidal drugs for neurocysticercosis: albendazole and praziquantel. ( Coffey, CS; Del Brutto, OH; García, HH; Roos, KL, 2006)
" Conclusion: Praziquantel is effective and safe in the treatment of patients with neurocysticercosis."5.72Efficacy and safety of praziquantel in the treatment of neurocysticercosis in Vietnam. ( Loi, CB; Phuc, TQ; Thang, TD; Thanh, DT; Thieu, NQ; Tho, TH; Tran-Anh, L, 2022)
"Praziquantel (PZQ) has been commonly used to treat diverse parasitic infections for over thirty years."5.56Acute pancytopenia due to praziquantel treatment for cerebral cysticercosis: A rare case report. ( Deng, H; Fu, Y; Lai, J; Li, Q; Zhang, Y, 2020)
"Our study demonstrates the safety and efficacy of albendazole and praziquantel in combination for complete radiologic resolution in children with persistent neurocysticercosis when compared with albendazole monotherapy or placebo."5.51Efficacy of Combination Therapy of Albendazole and Praziquantel vs Albendazole Monotherapy in Children With Persistent Neurocysticercosis: A Randomized Controlled Trial. ( Khandelwal, N; Saini, AG; Singh, K; Singhi, P, 2022)
"Neurocysticercosis is the most common parasitic infection of the nervous system and currently represents a serious public health issue in many regions of Latin America, Asia, and Africa."5.48In vivo treatment of experimental neurocysticercosis with praziquantel nanosuspensions-a metabolic approach. ( Arrua, EC; Lima, NF; Salomon, CJ; Silva, LD; Vinaud, MC, 2018)
"The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms."5.46Radiological evolution of porcine neurocysticercosis after combined antiparasitic treatment with praziquantel and albendazole. ( Arroyo, G; Bustos, JA; Calcina, J; Cangalaya, C; Chacaltana, J; García, HH; Gonzalez, AE; Guerra-Giraldez, C; Mahanty, S; Mamani, J; Nash, TE; Suarez, D; Vargas-Calla, A, 2017)
"In this double-blind, placebo-controlled, phase 3 trial, patients with viable intraparenchymal neurocysticercosis were randomly assigned to receive 10 days of combined albendazole (15 mg/kg per day) plus praziquantel (50 mg/kg per day), standard albendazole (15 mg/kg per day), or increased dose albendazole (22·5 mg/kg per day)."5.19Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial. ( Bustos, JA; Escalante, D; Garcia, HH; Gavidia, M; Gonzales, I; Lescano, AG; Najar, E; Pretell, EJ; Rodriguez, L; Saavedra, H; Umeres, H; Zimic, M, 2014)
"To evaluate the efficacy and safety of a combination of albendazole and praziquantel in children with seizures and single small enhancing computerized tomographic lesions."5.14Combination therapy with albendazole and praziquantel versus albendazole alone in children with seizures and single lesion neurocysticercosis: a randomized, placebo-controlled double blind trial. ( Kaur, S; Khandelwal, N; Singhi, P; Singhi, S, 2009)
"A recently described one-day regimen of praziquantel (PZQ) therapy for neurocysticercosis (NCC), three doses of 25 mg/k given at 2 h intervals, was applied in eight patients with viable NCC cysts without any evidence of inflammation."5.09Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions. ( García, HH; Gilman, RH; Martinez, M; Pretell, EJ; Saavedra, H, 2001)
"18 patients with partial epilepsy and neurocysticercosis were treated with albendazol or praziquantel and followed from 3 months to 12 years."5.09Cysticidal therapy: impact on seizure control in epilepsy associated with neurocysticercosis. ( Cardoso, TM; Cendes, F; Guerreiro, CA; Kobayashi, E; Santos, IC, 2000)
"Anthelminthic treatment with albendazole provides improved rates of seizure freedom and hastens resolution of the granuloma."4.89Drug therapy for solitary cysticercus granuloma: a systematic review and meta-analysis. ( Otte, WM; Sander, JW; Singh, G; Singla, M, 2013)
"A critical review of the available data from comparative trials suggests that albendazole is more effective than praziquantel regarding clinically important outcomes in patients with neurocysticercosis."4.84Albendazole versus praziquantel in the treatment of neurocysticercosis: a meta-analysis of comparative trials. ( Adamidi, ES; Falagas, ME; Matthaiou, DK; Panos, G, 2008)
"Therapy for neurocysticercosis has advanced during the last 20 years with the advent of albendazole (Zentel) and praziquantel (Cysticide)."4.82Therapy for neurocysticercosis. ( Takayanagui, OM, 2004)
"Four trials met the inclusion criteria, treating intraparenchymatous neurocysticercosis with either albendazole or praziquantel compared to placebo or no treatment."4.80Treating neurocysticercosis medically: a systematic review of randomized, controlled trials. ( Counsell, C; Garner, P; Gelband, H; Prasad, K; Salinas, R, 1999)
"Cyst resolution was unsatisfactory with albendazole monotherapy but was very high when it was followed by a combination of albendazole and praziquantel."4.31Efficacy and safety of antiparasitic therapy for neurocysticercosis in rural Tanzania: a prospective cohort study. ( Bottieau, E; Carabin, H; Dorny, P; Fleury, A; Gabriël, S; Jackson, E; Magnussen, P; Makasi, C; Mwape, KE; Ngowi, BJ; Prazeres da Costa, C; Prodjinotho, UF; Ruether, C; Schmidt, V; Stelzle, D; Trevisan, C; Van Damme, I; Winkler, AS; Zulu, G, 2023)
"The current pharmacological treatment of neurocysticercosis is based on two drugs, praziquantel (PZQ) and albendazole; however, suboptimal efficacy has been documented."3.96Cysticidal activity of praziquantel-mebendazole combination: In vitro and in vivo studies. ( Fernanda, GM; Francisca, PA; Guadalupe, PH; Helgi, JC; Iliana, GH; Javier, LF; Nelly, C; Susana, RI, 2020)
"The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal."3.91Albendazole Sulfoxide Plasma Levels and Efficacy of Antiparasitic Treatment in Patients With Parenchymal Neurocysticercosis. ( Arroyo, G; Bonato, PS; Bustos, JA; Garcia, HH; Gilman, RH; Gonzales, I; Gonzalez, AE; Horton, J; Lanchote, VL; Lescano, AG; Pretell, EJ; Rodriguez, S; Saavedra, H; Takayanagui, OM, 2019)
"A patient with paucisymptomatic neurocysticercosis (NCC) diagnosed by Ag-ELISA, and confirmed by MRI images, was treated with praziquantel, albendazole and dexamethasone."3.91Monitoring treatment of Taenia solium- neurocysticercosis by detection of circulating antigens: a case report. ( Benítez-Ortiz, W; Carpio, A; Rodríguez-Hidalgo, R; Van den Enden, E, 2019)
"Albendazole is an anthelmintic drug widely used in the treatment of neurocysticercosis (NCC), an infection of the brain with Taenia solium cysts."3.79In vitro analysis of albendazole sulfoxide enantiomers shows that (+)-(R)-albendazole sulfoxide is the active enantiomer against Taenia solium. ( Cass, QB; de Campos Lourenço, T; Dorny, P; García, HH; Guerra-Giraldez, C; Mahanty, S; Marzal, M; Nash, TE; Paredes, A; Rivera, A, 2013)
" Lastly, widespread neurocysticercosis may be a concern in mass treatment programs that provide praziquantel (for managing schistosomiasis) or albendazole (for managing intestinal worms or lymphatic filariasis) because these drugs may kill cerebral cysticerci, resulting in severe adverse events."3.74Could neurocysticercosis be the cause of "onchocerciasis-associated" epileptic seizures? ( Eberhard, M; Habumogisha, P; Katabarwa, M; Lakwo, T; Richards, F, 2008)
" We report a case in which treatment with high-dose praziquantel resulted in prolonged perilesional edema requiring use of corticosteroids and corticosteroid-sparing agents for >1 year, suggesting a role for methotrexate in the management of this condition."3.72Prolonged perilesional edema after treatment of parenchymal neurocysticercosis: methotrexate as a corticosteroid-sparing agent. ( Keiser, PB; Nash, TE, 2003)
"In this study, 65 patients with active neurocysticercosis (NCC) treated with praziquantel or albendazole were retrospectively reviewed to evaluate radiological and clinical outcome."3.70Outcomes of medical treatment of neurocysticercosis: a study of 65 cases in Cheju Island, Korea. ( Cho, BK; Hong, KS; Kim, SK; Paek, SH; Wang, KC, 1999)
"Albendazole (ABZ) has been used together with praziquantel (PZQ) before for geohelminths, echinococcosis and cysticercosis, but their combined use is not yet formally recommended and only scarce, discrepant data exist on their pharmacokinetics when given together."2.76Pharmacokinetics of combined treatment with praziquantel and albendazole in neurocysticercosis. ( Bonato, PS; Bustos, JA; Garcia, HH; Gilman, RH; Gonzales, I; Gonzalez, AE; Horton, J; Lanchote, VL; Lescano, AG; Pretell, EJ; Saavedra, H; Takayanagui, OM, 2011)
"Neurocysticercosis is a parasitic infection of the central nervous system by the larval stage of the pork tapeworm and is a common cause of seizures and epilepsy in endemic areas."2.72Anthelmintics for people with neurocysticercosis. ( Abba, K; Monk, EJM; Ranganathan, LN, 2021)
"Neurocysticercosis is the most common parasitosis of the central nervous system."2.49Neurocysticercosis. ( Zymberg, ST, 2013)
"Human neurocysticercosis is a severe disease caused by the installation of Taenia solium larvae in the CNS."2.48Pharmacokinetic variability of anthelmintics: implications for the treatment of neurocysticercosis. ( Jung-Cook, H, 2012)
"Neurocysticercosis is an infection of the brain by the larval stage of the pork tapeworm."2.46Anthelmintics for people with neurocysticercosis. ( Abba, K; Ramaratnam, S; Ranganathan, LN, 2010)
"Neurocysticercosis is an infection of the brain by the larval stage of the pork tapeworm."2.46Anthelmintics for people with neurocysticercosis. ( Abba, K; Ramaratnam, S; Ranganathan, LN, 2010)
"Neurocysticercosis is a pleomorphic disease due to individual differences in the number and location of the parasites within the nervous system as well as to differences in the severity of the host's immune reaction against the parasite."2.43[Neurocysticercosis: up-dating in diagnosis and treatment]. ( Del Brutto, OH, 2005)
"55%; P = 0."2.43Meta-analysis: Cysticidal drugs for neurocysticercosis: albendazole and praziquantel. ( Coffey, CS; Del Brutto, OH; García, HH; Roos, KL, 2006)
" Conclusion: Praziquantel is effective and safe in the treatment of patients with neurocysticercosis."1.72Efficacy and safety of praziquantel in the treatment of neurocysticercosis in Vietnam. ( Loi, CB; Phuc, TQ; Thang, TD; Thanh, DT; Thieu, NQ; Tho, TH; Tran-Anh, L, 2022)
"Subarachnoid cysticercosis is a type of extra-parenchymal infection in which the prevalence is not known and racemose NC with cerebellar involvement has been rarely reported."1.62Subarachnoid racemose neurocysticercosis with cerebellar involvement: an old friend in an infrequent location? ( Calderon-Vargas, CM; Montejo-Coy, JA; Parra-Cárdenas, DM; Severiche-Bueno, DF; Vargas-Cuervo, MT, 2021)
"Praziquantel (PZQ) has been commonly used to treat diverse parasitic infections for over thirty years."1.56Acute pancytopenia due to praziquantel treatment for cerebral cysticercosis: A rare case report. ( Deng, H; Fu, Y; Lai, J; Li, Q; Zhang, Y, 2020)
"Neurocysticercosis is the most common parasitic infection of the nervous system and currently represents a serious public health issue in many regions of Latin America, Asia, and Africa."1.48In vivo treatment of experimental neurocysticercosis with praziquantel nanosuspensions-a metabolic approach. ( Arrua, EC; Lima, NF; Salomon, CJ; Silva, LD; Vinaud, MC, 2018)
"The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms."1.46Radiological evolution of porcine neurocysticercosis after combined antiparasitic treatment with praziquantel and albendazole. ( Arroyo, G; Bustos, JA; Calcina, J; Cangalaya, C; Chacaltana, J; García, HH; Gonzalez, AE; Guerra-Giraldez, C; Mahanty, S; Mamani, J; Nash, TE; Suarez, D; Vargas-Calla, A, 2017)
"Albendazole has better therapeutic effects than praziquantel."1.43[Clinical Analysis of 94 Patients with Neurocysticercosis in Sichuan Province]. ( Hu, TY; Liu, Y; Lv, XJ; Zhong, CJ, 2016)
"Taenia solium cysticercosis is a common parasitic infection of humans and pigs."1.42Successful Antiparasitic Treatment for Cysticercosis is Associated with a Fast and Marked Reduction of Circulating Antigen Levels in a Naturally Infected Pig Model. ( Bustos, JA; Castillo, Y; Dorny, P; Gabriël, S; Garcia, HH; Gilman, RH; Gonzalez, AE; Praet, N; Rodriguez, S; Zimic, M, 2015)
"When cerebral cysticercosis were in acute stage (the single and multiple sacculus type, encephalitis type, and macrocyst and sacculus coexistence type), the therapeutic effect was good; while in the mixed type, the therapeutic effect was relatively poor."1.40[Comparative study on EEG and neuroimaging of patients with cerebral cysticercosis before and after treatment]. ( Fu, TX; Hu, YX; Li, GL; Mao, DH; Tan, WB; Wang, ZL, 2014)
"Neurocysticercosis is a widely prevalent disease in the tropics that causes seizures and a variety into of neurological symptoms in most of the world."1.39Disruption of the blood-brain barrier in pigs naturally infected with Taenia solium, untreated and after anthelmintic treatment. ( Arroyo, G; Balboa, D; Cangalaya, C; García, HH; Gonzales-Gustavson, E; González, AE; Guerra-Giraldez, C; Mahanty, S; Marzal, M; Nash, TE; Orrego, MÁ; Paredes, A, 2013)
"Neurocysticercosis is an unusual cause of seizure in the New Zealand setting."1.38Neurocysticercosis: an unusual cause of seizure in the New Zealand setting. ( Heron, P; Pybus, M, 2012)
"Neurocysticercosis was easy to misdiagnose."1.35Clinical analysis of 52 cases of neurocysticercosis. ( Chaoshuang, L; Xiaohong, W; Zhanlian, H; Zhiliang, G; Zhixin, Z, 2008)
"Neurocysticercosis is a pathology that we are finding nowadays over the immigrant population."1.32[Neurocysticercosis: report of three cases and recommendations of treatment]. ( Alvarez Rodríguez, E; Cabello, J; Espinós Pérez, D; Gutiérrez Larráinzar, A; Torres-Gárate, R, 2004)
"Cysticercosis is an helminthic disease which is usually observed in endemic areas or in immigrants coming from these areas."1.32[Neurocysticercosis complicating the treatment of cutaneous cysticercosis in a traveller]. ( Bricaire, E; Caumes, E; Chemali, N; Danis, M; Epelboin, L; Klement, E, 2004)
"Cysticercosis is a disease caused by the hydatid of the porcine tapeworm (cysticercus)."1.32[Cysticercosis as a rare cause of a tumor of the tongue]. ( Gocht, A; Metternich, FU; Roth, B, 2003)
"A 29-year-old man presented focal seizure on the left side."1.31[A case of neurocysticercosis presenting as focal seizure]. ( Higuchi, H; Kobayashi, N; Okada, T; Sugiyama, M; Teramoto, A; Yabe, Y, 2000)
"Treatment with praziquantel associated with cimetidine to increase the drug bioavailability and prednisone to reduce the inflammatory reaction gives good results."1.30Parenchymatous cerebral neurocysticercosis in a quadriplegic patient. ( Al-Khodairy, AT; Annoni, JM; Uebelhart, D, 1999)

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (8.74)18.2507
2000's34 (33.01)29.6817
2010's46 (44.66)24.3611
2020's14 (13.59)2.80

Authors

AuthorsStudies
Singh, K1
Saini, AG1
Khandelwal, N2
Singhi, P2
Cunningham, FG1
Twickler, DM1
Takayanagui, OM6
Haes, TM1
Thang, TD1
Phuc, TQ1
Thanh, DT1
Thieu, NQ1
Tho, TH1
Loi, CB1
Tran-Anh, L1
Stelzle, D1
Makasi, C1
Schmidt, V1
Trevisan, C1
Van Damme, I1
Ruether, C1
Dorny, P3
Magnussen, P1
Zulu, G1
Mwape, KE1
Bottieau, E1
Prazeres da Costa, C1
Prodjinotho, UF1
Carabin, H1
Jackson, E1
Fleury, A3
Gabriël, S2
Ngowi, BJ1
Winkler, AS1
Nash, TE9
O'Connell, EM1
Hammoud, DA1
Wetzler, L1
Ware, JM2
Mahanty, S8
Francisca, PA1
Javier, LF1
Guadalupe, PH1
Fernanda, GM1
Nelly, C1
Helgi, JC1
Iliana, GH1
Susana, RI1
Del Brutto, OH8
Pérez-Jacoiste Asín, MA1
Calleja-Castaño, P1
Hilario, A1
Zhang, Y1
Fu, Y1
Deng, H1
Li, Q1
Lai, J1
Ramiandrasoa, NS1
Ravoniarimbinina, P1
Solofoniaina, AR1
Andrianjafy Rakotomanga, IP1
Andrianarisoa, SH1
Molia, S1
Labouche, AM1
Fahrion, AS1
Donadeu, M1
Abela-Ridder, B1
Rajaonatahina, D1
Landzberg, DR1
Dhir, A1
Jillella, DV1
Monk, EJM1
Abba, K3
Ranganathan, LN3
Parra-Cárdenas, DM1
Vargas-Cuervo, MT1
Montejo-Coy, JA1
Calderon-Vargas, CM1
Severiche-Bueno, DF1
Cangalaya, C4
Bustos, JA7
Calcina, J2
Vargas-Calla, A1
Mamani, J1
Suarez, D1
Arroyo, G4
Gonzalez, AE8
Chacaltana, J1
Guerra-Giraldez, C5
García, HH16
Orrego, MA2
Adrianzen, MP1
Liu, P1
Weng, X1
Zhou, J1
Xu, X1
He, F1
Du, Y1
Wu, H1
Gong, Y1
Peng, G1
Silva, LD1
Lima, NF1
Arrua, EC1
Salomon, CJ1
Vinaud, MC2
Liu, Y1
Hu, TY1
Zhong, CJ1
Lv, XJ1
Toledo, A1
Osorio, R1
Matus, C1
Martinez Lopez, Y1
Ramirez Cruz, N1
Sciutto, E2
Fragoso, G1
Arauz, A1
Carrillo-Mezo, R2
Coyle, CM1
Lescano, AG4
Gonzales, I5
Saavedra, H6
Rodriguez, S2
Pretell, EJ7
Bonato, PS3
Lanchote, VL3
Horton, J3
Gilman, RH6
Rodríguez-Hidalgo, R1
Carpio, A3
Van den Enden, E1
Benítez-Ortiz, W1
Marzal, M3
Balboa, D1
Paredes, A2
Gonzales-Gustavson, E1
Romo, ML2
Kelvin, EA1
de Almeida Leandro, L1
Fraga, CM1
de Souza Lino, R1
Karegowda, LH1
Shenoy, PM1
Prakashini, K1
Karur, G1
Singh, G3
White, AC1
Zimic, M3
Escalante, D1
Gavidia, M2
Rodriguez, L2
Najar, E2
Umeres, H2
Wang, ZL1
Fu, TX1
Hu, YX1
Li, GL1
Mao, DH1
Tan, WB1
Valadas, E1
Badura, R1
Marques, T1
Neno, M1
Boura, M1
Sutre, AF1
Beato, S1
Grácio, MA1
Neves, JC1
Ahmed, S1
Paul, SP1
Mahamat, A1
Abboud, P1
Demar, M1
JeanBourquin, D1
Djossou, F1
Wang, W1
Castillo, Y1
Praet, N1
Li, Y1
Sun, L1
Chen, C1
Yang, CM1
Ghasemi, R1
Rowe, A1
Shah, R1
Venkatesan, P1
England, TJ1
Chaoshuang, L1
Zhixin, Z1
Xiaohong, W1
Zhanlian, H1
Zhiliang, G1
Kaur, S1
Singhi, S1
Proaño, JV2
Torres-Corzo, J1
Rodríguez-Della Vecchia, R1
Guizar-Sahagun, G1
Rangel-Castilla, L1
Maïga, Y1
Diallo, M1
Bouteille, B1
Konate, A1
Diarra, M1
Maïga, M1
Marjolet, M1
Ramaratnam, S2
Cárdenas, G1
Jung, H2
Hernandez, JL1
Sotelo, J2
Diaz-Olavarrieta, C1
Hewagama, SS1
Darby, JD1
Sheorey, H1
Daffy, JR1
Pybus, M1
Heron, P1
Odashima, NS1
Lima, JE1
Jung-Cook, H1
Wandra, T1
Sudewi, AA1
Swastika, IK1
Sutisna, P1
Dharmawan, NS1
Yulfi, H1
Darlan, DM1
Kapti, IN1
Samaan, G1
Sato, MO1
Okamoto, M1
Sako, Y1
Ito, A1
Zymberg, ST1
Madrid, EM1
de Campos Lourenço, T1
Rivera, A1
Cass, QB1
Otte, WM1
Singla, M1
Sander, JW2
Al Shahrani, D1
Frayha, HH1
Dabbagh, O1
Al Shail, E1
Keiser, PB1
Narula, G1
Bawa, KS1
Roth, B1
Gocht, A1
Metternich, FU1
Guo, DM1
Xie, SP1
Jia, JP1
Kim, JS1
Jeong, SM1
Moon, SY1
Park, SH1
Alvarez Rodríguez, E1
Torres-Gárate, R1
Gutiérrez Larráinzar, A1
Cabello, J1
Espinós Pérez, D1
Sheehan, JP1
Sheehan, J1
Lopes, MB1
Jane, JA1
DeGiorgio, CM1
Houston, I1
Oviedo, S1
Sorvillo, F1
Pawlowski, ZS1
Roos, KL1
Coffey, CS1
Nogales-Gaete, J1
Arriagada, C1
Salinas, R4
Epelboin, L1
Klement, E1
Chemali, N1
Danis, M1
Bricaire, E1
Caumes, E1
Prasad, K3
Matthaiou, DK1
Panos, G1
Adamidi, ES1
Falagas, ME1
Katabarwa, M1
Lakwo, T1
Habumogisha, P1
Richards, F1
Eberhard, M1
Yee, T1
Barakos, JA1
Knight, RT1
Al-Khodairy, AT1
Annoni, JM1
Uebelhart, D1
Campos, X1
Sánchez, J1
Mosquera, A1
Isozumi, K1
Izumi, Y1
Monteiro, L1
Lopes, J1
Martins da Silva, A1
Counsell, C1
Gelband, H1
Garner, P1
Kim, SK1
Wang, KC1
Paek, SH1
Hong, KS1
Cho, BK1
Morales, NM1
Agapejev, S1
Morales, RR1
Padula, NA1
Lima, MM1
Djientcheu, VD1
Zona, G1
Rilliet, B1
Gogna, A1
Sugiyama, M1
Okada, T1
Higuchi, H1
Yabe, Y1
Kobayashi, N1
Teramoto, A1
Santos, IC1
Kobayashi, E1
Cardoso, TM1
Guerreiro, CA1
Cendes, F1
Custodio, N1
Padilla, C1
Alvarado, M1
Martinez, M2
Belo, M1
Grunitzky, EK1
Balogou, A1
Kowu, L1
Madrazo, I1
Avelar, F1
López-Félix, B1
Díaz, G1
Grijalva, I1
López-Gómez, M1
Castro, N1
Corona, T1
Lev, N1
Michowiz, S1
Inbar, E1
Coire, CI1
Pitlik, S1
Melamed, E1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Characteristics of Patients With Symptomatic Active Neurocysticercosis and Effect of Treatment on Symptoms, Lesions and Quality of Life in Resource-poor Rural Areas of Eastern Africa - TOPANA, a Multi-centre Prospective Cohort Study.[NCT03834337]63 participants (Actual)Observational2019-04-01Completed
Clinical, Laboratory and Imaging Features, Treatment Trends and Long Term Outcomes in Patients With Parenchymal and Extraparenchymal Neurocysticercosis-A Registry Based Study[NCT04706819]1,000 participants (Anticipated)Observational [Patient Registry]2021-01-15Not yet recruiting
Antiparasitic Therapy for Neurocysticercosis: Phase II/III Study on Safety and Efficacy of Combined Treatment With Praziquantel and Albendazole[NCT00441285]Phase 2/Phase 3156 participants (Actual)Interventional2010-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Phase III Trial - Proportion of Patients Without Remaining Live Cysts

Proportion of patients whose 6 month MR does not show viable parasites anymore (NCT00441285)
Timeframe: Day 180

Interventionparticipants (Number)
Phase III Trial - ABZ+PZQ25
Phase III Trial - Increased ABZ19
Phase III Trial - Standard ABZ15

PK Substudy - Area Under the Curve of Albendazole in Treatment Days 10 and 11

- To evaluate kinetic disposition of Albendazole we calculated the Area under the curve of the active metabolite of Albendazole (Albendazole Sulphoxide) with Praziquantel or Placebo (of Praziquantel). (NCT00441285)
Timeframe: 0.5, 1, 1.5, 2, 3, 4, 8, 10, 12, 24 and 36 hours post dose on Treatment days 10-11

Interventionng*h/ml (Mean)
Albendazole + Praziquantel4925.3
Albendazole + Placebo2969.6

PK Substudy - Area Under the Curve of Albendazole in Treatment in Day 1

- To evaluate kinetic disposition of Albendazole we calculated the Area under the curve of the active metabolite of Albendazole (Albendazole Sulphoxide) with Praziquantel or Placebo (of Praziquantel). (NCT00441285)
Timeframe: 0, 0.5, 1, 1.5, 2, 3, 4, 8, 10 and 12 hours post dose on Treatment day 1

Interventionng*h/mL (Mean)
Albendazole + Praziquantel1412.2
Albendazole + Placebo1111

PK Substudy - Area Under the Curve of Praziquantel by Antiepileptic Drug in Treatment Days 10 and 11

- To evaluate the kinetic disposition of Praziquantel by antiepileptic drug after the last praziquantel dose, we calculated the Area Under the Curve of Praziquantel with Carbamazepine or Phenytoin (NCT00441285)
Timeframe: 0.5, 1, 1.5, 2, 3, 4, 8, 10, 12, 24 and 36 hours post dose on treatment days 10-11

Interventionng*h/ml (Mean)
Carbamazepine240.2
Phenytoin550.1

PK Substudy - Maximum Concentration of Albendazole

Highest serum level of Albendazole measured from all level assessments in the curve. (NCT00441285)
Timeframe: Treatment day 1 and Treatment days 10-11

Interventionng/mL (Mean)
Albendazole + Praziquantel1293.9
Albendazole + Placebo2232.8

PK Substudy - Safety of Combined Albendazole Plus Praziquantel Therapy

- Describe if some Serious Adverse Event was associated to combined Albendazole plus Praziquantel therapy. (NCT00441285)
Timeframe: 90 days post tx

InterventionEvents (Number)
Albendazole + Praziquantel0
Albendazole + Placebo0

PK Substudy - Area Under the Curve of Praziquantel by Antiepileptic Drug in Treatment Day 1

- To evaluate the kinetic disposition of Praziquantel by antiepileptic drug after the last praziquantel dose, we calculated the Area Under the Curve of Praziquantel with Carbamazepine or Phenytoin (NCT00441285)
Timeframe: 0, 0.5, 1, 1.5, 2, 3, 4, 8, 10 and 12 hours post dose in treatment day 1

Interventionng*h / mL (Mean)
Carbamazepine (n=8)Phenytoin (n=8)
Albendazole + Praziquantel548.3923.7

Reviews

28 reviews available for praziquantel and Central Nervous System Cysticercosis

ArticleYear
Update on the diagnosis and management of neurocysticercosis.
    Arquivos de neuro-psiquiatria, 2022, Volume: 80, Issue:5 Suppl 1

    Topics: Albendazole; Epilepsy; Humans; Magnetic Resonance Imaging; Neurocysticercosis; Praziquantel

2022
Current approaches to cysticidal drug therapy for neurocysticercosis.
    Expert review of anti-infective therapy, 2020, Volume: 18, Issue:8

    Topics: Albendazole; Animals; Anthelmintics; Brain; Cysticercus; Drug Therapy, Combination; Humans; Neurocys

2020
Anthelmintics for people with neurocysticercosis.
    The Cochrane database of systematic reviews, 2021, 06-01, Volume: 6

    Topics: Adult; Albendazole; Anticestodal Agents; Bias; Brain Diseases; Child; Humans; Neurocysticercosis; Pl

2021
Antiparasitic treatment of neurocysticercosis - The effect of cyst destruction in seizure evolution.
    Epilepsy & behavior : E&B, 2017, Volume: 76

    Topics: Albendazole; Anticestodal Agents; Antiparasitic Agents; Brain; Cysts; Epilepsy; Female; Humans; Infl

2017
Neurocysticercosis.
    Arquivos de neuro-psiquiatria, 2013, Volume: 71, Issue:9B

    Topics: Albendazole; Anthelmintics; Humans; Neurocysticercosis; Praziquantel

2013
Neurocysticercosis.
    Handbook of clinical neurology, 2014, Volume: 121

    Topics: Animals; Antiparasitic Agents; Antiplatyhelmintic Agents; Humans; Neurocysticercosis; Neurosurgical

2014
Routine drug and food interactions during antihelminthic treatment of neurocysticercosis: a reason for the variable efficacy of albendazole and praziquantel?
    Journal of clinical pharmacology, 2014, Volume: 54, Issue:4

    Topics: Adrenal Cortex Hormones; Albendazole; Animals; Anthelmintics; Anticonvulsants; Drug Interactions; Hi

2014
Anthelmintics for people with neurocysticercosis.
    The Cochrane database of systematic reviews, 2010, Jan-20, Issue:1

    Topics: Adult; Albendazole; Anticestodal Agents; Brain Diseases; Child; Humans; Neurocysticercosis; Praziqua

2010
Anthelmintics for people with neurocysticercosis.
    The Cochrane database of systematic reviews, 2010, Mar-17, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Albendazole; Anticestodal Agents; Brain Diseases; Child; Humans; Neu

2010
Medical management of neurocysticercosis.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:18

    Topics: Albendazole; Animals; Anthelmintics; Brain Diseases; Humans; Life Cycle Stages; Magnetic Resonance I

2011
Pharmacokinetic variability of anthelmintics: implications for the treatment of neurocysticercosis.
    Expert review of clinical pharmacology, 2012, Volume: 5, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Humans; Neurocysticercosis; Praziquantel; Treatment Outcome

2012
Taeniasis/cysticercosis in Bali, Indonesia.
    The Southeast Asian journal of tropical medicine and public health, 2011, Volume: 42, Issue:4

    Topics: Animals; Anthelmintics; Cysticercosis; DNA, Helminth; DNA, Mitochondrial; Health Surveys; Humans; In

2011
Neurocysticercosis.
    World neurosurgery, 2013, Volume: 79, Issue:2 Suppl

    Topics: Animals; Antiplatyhelmintic Agents; Cerebral Ventricles; Endoscopy; Humans; Neurocysticercosis; Neur

2013
Drug therapy for solitary cysticercus granuloma: a systematic review and meta-analysis.
    Neurology, 2013, Jan-08, Volume: 80, Issue:2

    Topics: Adolescent; Albendazole; Anthelmintics; Anti-Inflammatory Agents; Calcinosis; Child; Child, Preschoo

2013
Neurocysticercosis--New Millennium, ancient disease and unending debate.
    Indian journal of pediatrics, 2003, Volume: 70, Issue:4

    Topics: Albendazole; Animals; Anthelmintics; Anticonvulsants; Humans; Neurocysticercosis; Praziquantel; Seiz

2003
Therapy for neurocysticercosis.
    Expert review of neurotherapeutics, 2004, Volume: 4, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Clinical Trials as Topic; Humans; Neurocysticercosis; Practice

2004
Intramedullary spinal cysticercosis. Case report and review of the literature.
    Neurosurgical focus, 2002, Jun-15, Volume: 12, Issue:6

    Topics: Adolescent; Anthelmintics; Cervical Vertebrae; Female; Hand; Humans; Laminectomy; Magnetic Resonance

2002
Deaths associated with cysticercosis. Report of three cases and review of the literature.
    Neurosurgical focus, 2002, Jun-15, Volume: 12, Issue:6

    Topics: Adult; Aged; Anthelmintics; Cerebrospinal Fluid Shunts; Fatal Outcome; Headache; Humans; Hydrocephal

2002
[Neurocysticercosis: up-dating in diagnosis and treatment].
    Neurologia (Barcelona, Spain), 2005, Volume: 20, Issue:8

    Topics: Albendazole; Animals; Anthelmintics; Antibodies; Humans; Neurocysticercosis; Praziquantel; Taenia so

2005
Role of chemotherapy of taeniasis in prevention of neurocysticercosis.
    Parasitology international, 2006, Volume: 55 Suppl

    Topics: Animals; Anticestodal Agents; Cysticercus; Humans; Neurocysticercosis; Niclosamide; Praziquantel; Ta

2006
Meta-analysis: Cysticidal drugs for neurocysticercosis: albendazole and praziquantel.
    Annals of internal medicine, 2006, Jul-04, Volume: 145, Issue:1

    Topics: Albendazole; Anthelmintics; Humans; Neurocysticercosis; Praziquantel; Radiography; Secondary Prevent

2006
[Treatment of neurocysticercosis: a review].
    Revista medica de Chile, 2006, Volume: 134, Issue:6

    Topics: Albendazole; Animals; Anthelmintics; Bacterial Vaccines; Evidence-Based Medicine; Humans; Neurocysti

2006
WITHDRAWN: Drugs for treating neurocysticercosis (tapeworm infection of the brain).
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:4

    Topics: Albendazole; Anticestodal Agents; Brain Diseases; Humans; Neurocysticercosis; Praziquantel; Trichlor

2007
Albendazole versus praziquantel in the treatment of neurocysticercosis: a meta-analysis of comparative trials.
    PLoS neglected tropical diseases, 2008, Mar-12, Volume: 2, Issue:3

    Topics: Albendazole; Clinical Trials as Topic; Humans; Neurocysticercosis; Praziquantel; Randomized Controll

2008
[Neurocysticercosis].
    Ryoikibetsu shokogun shirizu, 1999, Issue:24 Pt 2

    Topics: Albendazole; Animals; Anticestodal Agents; Diagnosis, Differential; Host-Parasite Interactions; Huma

1999
Treating neurocysticercosis medically: a systematic review of randomized, controlled trials.
    Tropical medicine & international health : TM & IH, 1999, Volume: 4, Issue:11

    Topics: Albendazole; Anthelmintics; Anticestodal Agents; Humans; Neurocysticercosis; Praziquantel; Randomize

1999
Drugs for treating neurocysticercosis (tapeworm infection of the brain).
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Albendazole; Anticestodal Agents; Brain Diseases; Humans; Neurocysticercosis; Praziquantel; Trichlor

2000
Neurocysticercosis.
    The Israel Medical Association journal : IMAJ, 2002, Volume: 4, Issue:1

    Topics: Anthelmintics; Brain; Brain Diseases; Female; Humans; Middle Aged; Neurocysticercosis; Praziquantel;

2002

Trials

11 trials available for praziquantel and Central Nervous System Cysticercosis

ArticleYear
Efficacy of Combination Therapy of Albendazole and Praziquantel vs Albendazole Monotherapy in Children With Persistent Neurocysticercosis: A Randomized Controlled Trial.
    Journal of child neurology, 2022, Volume: 37, Issue:5

    Topics: Adolescent; Albendazole; Anthelmintics; Child; Child, Preschool; Drug Therapy, Combination; Humans;

2022
Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial.
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Aged; Albendazole; Anthelmintics; Double-Blind Method; Drug-Related Side Effects

2014
Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial.
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Aged; Albendazole; Anthelmintics; Double-Blind Method; Drug-Related Side Effects

2014
Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial.
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Aged; Albendazole; Anthelmintics; Double-Blind Method; Drug-Related Side Effects

2014
Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial.
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Aged; Albendazole; Anthelmintics; Double-Blind Method; Drug-Related Side Effects

2014
Cysticidal Efficacy of Combined Treatment With Praziquantel and Albendazole for Parenchymal Brain Cysticercosis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, 06-01, Volume: 62, Issue:11

    Topics: Adolescent; Adult; Albendazole; Animals; Anticestodal Agents; Brain Diseases; Female; Humans; Male;

2016
Combination therapy with albendazole and praziquantel versus albendazole alone in children with seizures and single lesion neurocysticercosis: a randomized, placebo-controlled double blind trial.
    The Pediatric infectious disease journal, 2009, Volume: 28, Issue:5

    Topics: Adolescent; Albendazole; Animals; Anthelmintics; Child; Child, Preschool; Double-Blind Method; Drug

2009
Pharmacokinetics of combined treatment with praziquantel and albendazole in neurocysticercosis.
    British journal of clinical pharmacology, 2011, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Albendazole; Animals; Anthelmintics; Drug Therapy, Combination; Female; Humans; M

2011
Single-day praziquantel versus 1-week albendazole for neurocysticercosis.
    Neurology, 1999, Mar-23, Volume: 52, Issue:5

    Topics: Adult; Aged; Albendazole; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neurocyst

1999
Cysticidal therapy: impact on seizure control in epilepsy associated with neurocysticercosis.
    Arquivos de neuro-psiquiatria, 2000, Volume: 58, Issue:4

    Topics: Adult; Aged; Albendazole; Anticestodal Agents; Epilepsy; Follow-Up Studies; Humans; Magnetic Resonan

2000
Short regimen of praziquantel in the treatment of single brain enhancing lesions.
    Clinical neurology and neurosurgery, 2000, Volume: 102, Issue:4

    Topics: Adolescent; Adult; Animals; Anthelmintics; Female; Humans; Male; Middle Aged; Neurocysticercosis; Pr

2000
Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions.
    Clinical neurology and neurosurgery, 2001, Volume: 103, Issue:3

    Topics: Adult; Animals; Anthelmintics; Brain Diseases; Cysticercus; Female; Humans; Male; Middle Aged; Neuro

2001
Medical treatment for neurocysticercosis characterized by giant subarachnoid cysts.
    The New England journal of medicine, 2001, Sep-20, Volume: 345, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albendazole; Anticestodal Agents; Brain Diseases; Dexame

2001
Optimization of the single-day praziquantel therapy for neurocysticercosis.
    Neurology, 2001, Nov-27, Volume: 57, Issue:10

    Topics: Adolescent; Adult; Cimetidine; Dietary Carbohydrates; Dose-Response Relationship, Drug; Drug Adminis

2001

Other Studies

64 other studies available for praziquantel and Central Nervous System Cysticercosis

ArticleYear
Neurocysticercosis Complicating Pregnancy.
    Obstetrics and gynecology, 2022, 08-01, Volume: 140, Issue:2

    Topics: Albendazole; Anthelmintics; Female; Headache; Humans; Hydrocephalus; Infant, Newborn; Neurocysticerc

2022
Efficacy and safety of praziquantel in the treatment of neurocysticercosis in Vietnam.
    Tropical biomedicine, 2022, Sep-01, Volume: 39, Issue:3

    Topics: Alanine Transaminase; Albendazole; Anthelmintics; Anticonvulsants; Antiparasitic Agents; Aspartate A

2022
Efficacy and safety of antiparasitic therapy for neurocysticercosis in rural Tanzania: a prospective cohort study.
    Infection, 2023, Volume: 51, Issue:4

    Topics: Albendazole; Anthelmintics; Antiparasitic Agents; Cysts; Humans; Neurocysticercosis; Praziquantel; P

2023
Natural History of Treated Subarachnoid Neurocysticercosis.
    The American journal of tropical medicine and hygiene, 2020, Volume: 102, Issue:1

    Topics: Adolescent; Adult; Albendazole; Animals; Anthelmintics; Anti-Inflammatory Agents; Antigens, Helminth

2020
Cysticidal activity of praziquantel-mebendazole combination: In vitro and in vivo studies.
    Acta tropica, 2020, Volume: 202

    Topics: Albendazole; Animals; Anthelmintics; Blood-Brain Barrier; Cysticercosis; Drug Combinations; Mebendaz

2020
Lumbosacral Radiculopathy as the Clinical Presentation of Neurocysticercosis.
    The American journal of tropical medicine and hygiene, 2020, Volume: 102, Issue:6

    Topics: Adult; Albendazole; Anthelmintics; Anti-Inflammatory Agents; Antibodies, Helminth; Female; Humans; I

2020
Acute pancytopenia due to praziquantel treatment for cerebral cysticercosis: A rare case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2020, Volume: 26, Issue:10

    Topics: Aged; Cysticercosis; Humans; Male; Middle Aged; Neurocysticercosis; Pancytopenia; Praziquantel

2020
Impact of a 3-year mass drug administration pilot project for taeniasis control in Madagascar.
    PLoS neglected tropical diseases, 2020, Volume: 14, Issue:9

    Topics: Adult; Animals; Child; Cross-Sectional Studies; Feces; Humans; Madagascar; Mass Drug Administration;

2020
Radiographic Improvement of Larval Cysts in Neurocysticercosis.
    Annals of neurology, 2021, Volume: 89, Issue:2

    Topics: Adult; Albendazole; Anthelmintics; Anticonvulsants; Brain; Humans; Magnetic Resonance Imaging; Male;

2021
Subarachnoid racemose neurocysticercosis with cerebellar involvement: an old friend in an infrequent location?
    Revista do Instituto de Medicina Tropical de Sao Paulo, 2021, Volume: 63

    Topics: Cysticercosis; Friends; Humans; Neurocysticercosis; Praziquantel

2021
Radiological evolution of porcine neurocysticercosis after combined antiparasitic treatment with praziquantel and albendazole.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:6

    Topics: Albendazole; Animals; Anthelmintics; Brain; Cysts; Disease Models, Animal; Drug Therapy, Combination

2017
TNF-α blockade suppresses pericystic inflammation following anthelmintic treatment in porcine neurocysticercosis.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:11

    Topics: Animals; Anticestodal Agents; Antiparasitic Agents; Blood-Brain Barrier; Brain; Cytokines; Dexametha

2017
Next generation sequencing based pathogen analysis in a patient with neurocysticercosis: a case report.
    BMC infectious diseases, 2018, 03-06, Volume: 18, Issue:1

    Topics: Adult; Animals; Anthelmintics; Brain; DNA, Helminth; Female; Headache; High-Throughput Nucleotide Se

2018
In vivo treatment of experimental neurocysticercosis with praziquantel nanosuspensions-a metabolic approach.
    Drug delivery and translational research, 2018, Volume: 8, Issue:5

    Topics: Animals; Anthelmintics; Cysticercus; Disease Models, Animal; Drug Stability; Metabolome; Metabolomic

2018
[Clinical Analysis of 94 Patients with Neurocysticercosis in Sichuan Province].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2016, Volume: 34, Issue:2

    Topics: Adult; Albendazole; Antibodies; China; Diagnostic Errors; Enzyme-Linked Immunosorbent Assay; Female;

2016
Human Extraparenchymal Neurocysticercosis: The Control of Inflammation Favors the Host…but Also the Parasite.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Adrenal Cortex Hormones; Animals; Anthelmintics; Biomarkers; Brain; Drug Therapy, Combination; Foodb

2018
Etanercept to Control Inflammation in the Treatment of Complicated Neurocysticercosis.
    The American journal of tropical medicine and hygiene, 2019, Volume: 100, Issue:3

    Topics: Adult; Albendazole; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Etanercept; Female; Huma

2019
Albendazole Sulfoxide Plasma Levels and Efficacy of Antiparasitic Treatment in Patients With Parenchymal Neurocysticercosis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 11-13, Volume: 69, Issue:11

    Topics: Adolescent; Adult; Aged; Albendazole; Anthelmintics; Chromatography, High Pressure Liquid; Female; H

2019
Monitoring treatment of Taenia solium- neurocysticercosis by detection of circulating antigens: a case report.
    BMC neurology, 2019, Apr-03, Volume: 19, Issue:1

    Topics: Adult; Animals; Anthelmintics; Antibodies, Helminth; Enzyme-Linked Immunosorbent Assay; Humans; Male

2019
Disruption of the blood-brain barrier in pigs naturally infected with Taenia solium, untreated and after anthelmintic treatment.
    Experimental parasitology, 2013, Volume: 134, Issue:4

    Topics: Animals; Anthelmintics; Blood-Brain Barrier; Brain; Coloring Agents; Evans Blue; Extravasation of Di

2013
Partial reverse of the TCA cycle is enhanced in Taenia crassiceps experimental neurocysticercosis after in vivo treatment with anthelminthic drugs.
    Parasitology research, 2014, Volume: 113, Issue:4

    Topics: Albendazole; Animals; Anthelmintics; Brain; Chromatography, High Pressure Liquid; Citric Acid Cycle;

2014
A rare case of racemose neurocysticercosis of the posterior fossa.
    BMJ case reports, 2014, May-26, Volume: 2014

    Topics: Adult; Anthelmintics; Brain; Cerebellopontine Angle; Craniotomy; Fourth Ventricle; Humans; Hydroceph

2014
Determining better treatments for neurocysticercosis.
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:8

    Topics: Albendazole; Anthelmintics; Female; Humans; Male; Neurocysticercosis; Praziquantel

2014
Treatment of neurocysticercosis.
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:8

    Topics: Albendazole; Anthelmintics; Female; Humans; Male; Neurocysticercosis; Praziquantel

2014
[Comparative study on EEG and neuroimaging of patients with cerebral cysticercosis before and after treatment].
    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control, 2014, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Aged; Albendazole; Antiparasitic Agents; Electroencephalography; Female; Humans;

2014
A case of imported neurocysticercosis in Portugal.
    Journal of infection in developing countries, 2015, Jan-15, Volume: 9, Issue:1

    Topics: Anthelmintics; Cerebrospinal Fluid; Female; Guinea-Bissau; Head; Humans; Magnetic Resonance Imaging;

2015
Intramedullary spinal neurocysticercosis treated successfully with medical therapy.
    Journal of the Egyptian Society of Parasitology, 2014, Volume: 44, Issue:3

    Topics: Anthelmintics; Humans; Male; Neurocysticercosis; Praziquantel; Spinal Diseases; Young Adult

2014
Combined antiparasitic treatment for neurocysticercosis.
    The Lancet. Infectious diseases, 2015, Volume: 15, Issue:3

    Topics: Albendazole; Anthelmintics; Female; Humans; Male; Neurocysticercosis; Praziquantel

2015
Combined antiparasitic treatment for neurocysticercosis.
    The Lancet. Infectious diseases, 2015, Volume: 15, Issue:3

    Topics: Albendazole; Anthelmintics; Female; Humans; Male; Neurocysticercosis; Praziquantel

2015
Combined antiparasitic treatment for neurocysticercosis.
    The Lancet. Infectious diseases, 2015, Volume: 15, Issue:3

    Topics: Albendazole; Anthelmintics; Female; Humans; Male; Neurocysticercosis; Praziquantel

2015
Combined antiparasitic treatment for neurocysticercosis - Authors' reply.
    The Lancet. Infectious diseases, 2015, Volume: 15, Issue:3

    Topics: Albendazole; Anthelmintics; Female; Humans; Male; Neurocysticercosis; Praziquantel

2015
Successful Antiparasitic Treatment for Cysticercosis is Associated with a Fast and Marked Reduction of Circulating Antigen Levels in a Naturally Infected Pig Model.
    The American journal of tropical medicine and hygiene, 2015, Volume: 93, Issue:6

    Topics: Albendazole; Animals; Anticestodal Agents; Antigens, Helminth; Benzimidazoles; Cysticercosis; Diseas

2015
Inflammation Caused by Praziquantel Treatment Depends on the Location of the Taenia solium Cysticercus in Porcine Neurocysticercosis.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:12

    Topics: Animals; Anthelmintics; Brain; Histocytochemistry; Inflammation; Meninges; Neurocysticercosis; Prazi

2015
[Clinical application of diagnostic therapy of praziquantel for suspected cere- bral cysticercosis].
    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control, 2015, Volume: 27, Issue:5

    Topics: Adolescent; Adult; Aged; Animals; Anthelmintics; Child; Child, Preschool; Cysticercus; Drug Administ

2015
Neurocysticercosis presenting as a 'Stroke Mimic'.
    Acute medicine, 2016, Volume: 15, Issue:2

    Topics: Albendazole; Anticestodal Agents; Brain; Diagnosis, Differential; Glucocorticoids; Humans; Magnetic

2016
Clinical analysis of 52 cases of neurocysticercosis.
    Tropical doctor, 2008, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Albendazole; Anthelmintics; Brain; Brain Diseases; Child; China; Female; Humans;

2008
Intraventricular and subarachnoid basal cisterns neurocysticercosis: a comparative study between traditional treatment versus neuroendoscopic surgery.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009, Volume: 25, Issue:11

    Topics: Adolescent; Adult; Aged; Albendazole; Anthelmintics; Cerebral Ventricles; Child; Female; Follow-Up S

2009
[About an autochtonous case of neurocysticercosis in Mali].
    Bulletin de la Societe de pathologie exotique (1990), 2009, Volume: 102, Issue:4

    Topics: Albendazole; Anthelmintics; Brain Edema; Calcinosis; Consciousness Disorders; Diet; Drug Therapy, Co

2009
Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series.
    BMC neurology, 2010, Mar-04, Volume: 10

    Topics: Adult; Aged; Albendazole; Anthelmintics; Brain; Female; Humans; Magnetic Resonance Imaging; Male; Me

2010
Neurocysticercosis: changes after 25 years of medical therapy.
    Archives of medical research, 2010, Volume: 41, Issue:1

    Topics: Anthelmintics; Humans; Neurocysticercosis; Praziquantel

2010
Seizures related to praziquantel therapy in neurocysticercosis.
    The Medical journal of Australia, 2010, Aug-16, Volume: 193, Issue:4

    Topics: Anthelmintics; Humans; Male; Neurocysticercosis; Praziquantel; Seizures; Young Adult

2010
Neurocysticercosis: an unusual cause of seizure in the New Zealand setting.
    Journal of paediatrics and child health, 2012, Volume: 48, Issue:3

    Topics: Anthelmintics; Child; Humans; Male; Neurocysticercosis; New Zealand; Praziquantel; Radiography; Seiz

2012
Neurocysticercosis in Australia: still free of autochthonous cases?
    The Medical journal of Australia, 2012, Apr-02, Volume: 196, Issue:6

    Topics: Anthelmintics; Female; Frontal Lobe; Humans; Male; Neurocysticercosis; Praziquantel; Refugees; Seizu

2012
Quantitative screening for anticestode drugs based on changes in baseline enzyme secretion by Taenia crassiceps.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Alkaline Phosphatase; Animals; Anticestodal Agents; Artemisinins; Artesunate; Benzamides; Epilepsy;

2013
In vitro analysis of albendazole sulfoxide enantiomers shows that (+)-(R)-albendazole sulfoxide is the active enantiomer against Taenia solium.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Albendazole; Alkaline Phosphatase; Animals; Anticestodal Agents; Neurocysticercosis; Praziquantel; S

2013
First case of neurocysticercosis in Saudi Arabia.
    Journal of tropical pediatrics, 2003, Volume: 49, Issue:1

    Topics: Brain Diseases; Female; Humans; Infant; Neurocysticercosis; Praziquantel; Saudi Arabia

2003
Prolonged perilesional edema after treatment of parenchymal neurocysticercosis: methotrexate as a corticosteroid-sparing agent.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, May-15, Volume: 36, Issue:10

    Topics: Adrenal Cortex Hormones; Albendazole; Animals; Anthelmintics; Edema; Humans; Male; Methotrexate; Mid

2003
[Cysticercosis as a rare cause of a tumor of the tongue].
    Laryngo- rhino- otologie, 2003, Volume: 82, Issue:8

    Topics: Adult; Anthelmintics; Cerebral Cortex; Combined Modality Therapy; Cysticercosis; Diagnosis, Differen

2003
[Therapeutic efficacy of praziquantel, albendazole and a combination of the two drugs in cysticercosis].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2003, Volume: 21, Issue:3

    Topics: Adult; Albendazole; Anthelmintics; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Neu

2003
Anticysticercal treatment and seizures in neurocysticercosis.
    The Lancet. Neurology, 2004, Volume: 3, Issue:4

    Topics: Albendazole; Animals; Anthelmintics; Clinical Trials as Topic; Humans; Neurocysticercosis; Praziquan

2004
Third cranial nerve palsy from midbrain neurocysticercosis: repeated exacerbation on tapering corticosteroids.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2004, Volume: 24, Issue:3

    Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Blepharoptosis; Cerebrospinal Fluid; Cysticerc

2004
[Neurocysticercosis: report of three cases and recommendations of treatment].
    Anales de medicina interna (Madrid, Spain : 1984), 2004, Volume: 21, Issue:8

    Topics: Adult; Anthelmintics; Female; Humans; Magnetic Resonance Imaging; Male; Neurocysticercosis; Practice

2004
[Neurocysticercosis complicating the treatment of cutaneous cysticercosis in a traveller].
    Bulletin de la Societe de pathologie exotique (1990), 2004, Volume: 97, Issue:4

    Topics: Adult; Albendazole; Anthelmintics; Brain Edema; Combined Modality Therapy; Confusion; Cysticercosis;

2004
Could neurocysticercosis be the cause of "onchocerciasis-associated" epileptic seizures?
    The American journal of tropical medicine and hygiene, 2008, Volume: 78, Issue:3

    Topics: Albendazole; Animals; Anthelmintics; Epilepsy; Humans; Neurocysticercosis; Onchocerca; Onchocerciasi

2008
High-dose praziquantel with cimetidine for refractory neurocysticercosis: a case report with clinical and MRI follow-up.
    The Western journal of medicine, 1999, Volume: 170, Issue:2

    Topics: Adult; Antiplatyhelmintic Agents; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Neuro

1999
Parenchymatous cerebral neurocysticercosis in a quadriplegic patient.
    Spinal cord, 1999, Volume: 37, Issue:2

    Topics: Animals; Anticestodal Agents; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neck; Nervous S

1999
Relationship between cysticercosis and epilepsy.
    Epilepsia, 1999, Volume: 40, Issue:10

    Topics: Albendazole; Animals; Anthelmintics; Anticestodal Agents; Drug Administration Schedule; Epilepsy; Hu

1999
Heavy nonencephalitic cerebral cysticercosis in tapeworm carriers. The Cysticercosis Working Group in Perú.
    Neurology, 1999, Oct-22, Volume: 53, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Albendazole; Animals; Anthelmintics; Brain Diseases; Car

1999
Outcomes of medical treatment of neurocysticercosis: a study of 65 cases in Cheju Island, Korea.
    Surgical neurology, 1999, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albendazole; Anthelmintics; Female; Follow-Up Studies; H

1999
Clinical aspects of neurocysticercosis in children.
    Pediatric neurology, 2000, Volume: 22, Issue:4

    Topics: Albendazole; Anthelmintics; Antiprotozoal Agents; Brazil; Child; Child, Preschool; Eosinophils; Epil

2000
Neurocysticercosis: migration and proliferation of cysticercus in a CSF valve.
    British journal of neurosurgery, 2000, Volume: 14, Issue:2

    Topics: Albendazole; Anthelmintics; Humans; Hydrocephalus; Male; Middle Aged; Neurocysticercosis; Praziquant

2000
Praziquantel therapy in neurocysticercosis.
    The Journal of the Association of Physicians of India, 1996, Volume: 44, Issue:2

    Topics: Albendazole; Anthelmintics; Brain; Humans; Neurocysticercosis; Praziquantel; Sensitivity and Specifi

1996
[A case of neurocysticercosis presenting as focal seizure].
    No shinkei geka. Neurological surgery, 2000, Volume: 28, Issue:9

    Topics: Adult; Albendazole; Anthelmintics; Brain Diseases; Combined Modality Therapy; Humans; Male; Neurocys

2000
[Cerebral cysticercosis and headache in a young Togolese woman].
    Revue neurologique, 2001, Volume: 157, Issue:4

    Topics: Adult; Anthelmintics; Brain Diseases; Female; France; Headache; Humans; Neurocysticercosis; Praziqua

2001