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praziquantel and Bunostomiasis

praziquantel has been researched along with Bunostomiasis in 29 studies

azinox: Russian drug

Research Excerpts

ExcerptRelevanceReference
" In addition, although mebendazole has been extensively used together with praziquantel against infections with schistosomiasis and soil-transmitted helminthiasis (STH) in school-aged children, no specific acceptability or safety studies have been published on this drug combination in younger children."9.15The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda. ( Kabatereine, NB; Namwanje, H; Olsen, A, 2011)
" In addition, although mebendazole has been extensively used together with praziquantel against infections with schistosomiasis and soil-transmitted helminthiasis (STH) in school-aged children, no specific acceptability or safety studies have been published on this drug combination in younger children."5.15The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda. ( Kabatereine, NB; Namwanje, H; Olsen, A, 2011)
" However, the optimal time points post-treatment for assessing the efficacy of praziquantel against Schistosoma mansoni and albendazole against hookworm infections are not known."3.75Sequential analysis of helminth egg output in human stool samples following albendazole and praziquantel administration. ( Allangba, A; Lohourignon, LK; N'Goran, EK; Scherrer, AU; Sjöberg, MK; Traoré, M; Tschannen, AB; Utzinger, J, 2009)
"A school- and chemotherapy-based urinary schistosomiasis and intestinal helminth infection control programme was conducted in Matuga Division, Kwale District, Coast Province with teachers taking care of diagnosis, treatment and health education."2.68A school-based approach to the control of urinary schistosomiasis and intestinal helminth infections in children in Matuga, Kenya: impact of a two-year chemotherapy programme on prevalence and intensity of infections. ( Magnussen, P; Muchiri, E; Mungai, P; Ndzovu, M; Ouma, J; Tosha, S, 1997)
"Praziquantel treatment did not decrease the infection intensity of STHs."1.36Reduction in hookworm infection after praziquantel treatment among children and young adults in Leyte, the Philippines. ( Acosta, LP; Aggarwal, N; Coutinho, HM; Friedman, JF; Jiz, MA; Kurtis, JD; Leenstra, T; McGarvey, ST; Olveda, RM; Shaw, JG; Wu, HW, 2010)
"The combined effect of the Lymphatic Filariasis Elimination Programme (LFEP) and the National Schistosomiasis and Soil-transmitted Helminthiasis Control Programme (NSSCP) on soil-transmitted helminthiasis (STH) was evaluated."1.35The combined effect of the Lymphatic Filariasis Elimination Programme and the Schistosomiasis and Soil-transmitted Helminthiasis Control Programme on soil-transmitted helminthiasis in schoolchildren in Tanzania. ( Magnussen, P; Massa, K; Ndawi, B; Ntakamulenga, R; Olsen, A; Sheshe, A, 2009)
"haematobium and hookworm infections were significantly lower in the ComDT approach villages compared to the school-based approach villages (10."1.35The effect of the community-directed treatment approach versus the school-based treatment approach on the prevalence and intensity of schistosomiasis and soil-transmitted helminthiasis among schoolchildren in Tanzania. ( Magnussen, P; Massa, K; Ndawi, B; Ntakamulenga, R; Olsen, A; Sheshe, A, 2009)
"Mass treatment with praziquantel and albendazole led to a significant decrease in the intensity of Schistosoma mansoni - 70% (95% confidence interval (CI): 66-73%) after one year and 82% (95% CI: 80-85%) after two years of treatment."1.34Impact of a national helminth control programme on infection and morbidity in Ugandan schoolchildren. ( Brooker, S; Fenwick, A; Fleming, FM; Kabatereine, NB; Kazibwe, F; Koukounari, A; Stothard, JR; Tukahebwa, EM; Webster, JP; Zhang, Y, 2007)
"The effect of coinfection on HIV disease progression varied with species."1.32Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda. ( Brown, M; Elliott, AM; Hughes, P; Kizza, M; Quigley, MA; Rowland, S; Watera, C; Whitworth, JA, 2004)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.90)18.7374
1990's3 (10.34)18.2507
2000's11 (37.93)29.6817
2010's11 (37.93)24.3611
2020's2 (6.90)2.80

Authors

AuthorsStudies
Balk, JD1
Mitchell, ND1
Hughes, J1
Soto Nauto, P1
Rossi, J1
Ramirez-Barrios, R1
Jimenez Castro, PD1
Mansour, A1
Charles, S2
Hostetler, J1
Settje, T1
Kulke, D1
Kaplan, RM1
Njenga, SM1
Mutungi, FM1
Wamae, CN1
Mwanje, MT1
Njiru, KK1
Bockarie, MJ1
Pinot de Moira, A2
Fitzsimmons, CM2
Jones, FM2
Wilson, S2
Cahen, P1
Tukahebwa, E2
Mpairwe, H2
Mwatha, JK2
Bethony, JM2
Skov, PS1
Kabatereine, NB5
Dunne, DW3
Kinung'hi, SM1
Magnussen, P5
Kishamawe, C1
Todd, J1
Vennervald, BJ1
Chami, GF1
Kontoleon, AA1
Bulte, E1
Fenwick, A2
Tukahebwa, EM2
Massa, K2
Sheshe, A2
Ntakamulenga, R2
Ndawi, B2
Olsen, A3
Scherrer, AU1
Sjöberg, MK1
Allangba, A1
Traoré, M1
Lohourignon, LK1
Tschannen, AB1
N'Goran, EK2
Utzinger, J2
Schimmel, A1
Altreuther, G1
Schroeder, I1
Cruthers, L1
Ketzis, J1
Kok, DJ1
Kraemer, F1
McCall, JW1
Krieger, KJ1
Smith, JL1
Brooker, S3
Shaw, JG1
Aggarwal, N1
Acosta, LP1
Jiz, MA1
Wu, HW1
Leenstra, T1
Coutinho, HM1
Olveda, RM1
Kurtis, JD1
McGarvey, ST1
Friedman, JF1
Namwanje, H1
Elliott, AM2
Ndibazza, J1
Muhangi, L1
Webb, EL1
Kizito, D1
Mawa, P1
Tweyongyere, R1
Muwanga, M1
Hodges, MH1
Dada, N1
Warmsley, A1
Paye, J1
Bangura, MM1
Nyorkor, E1
Sonnie, M1
Zhang, Y2
Mwinzi, PN1
Montgomery, SP1
Owaga, CO1
Mwanje, M1
Muok, EM1
Ayisi, JG1
Laserson, KF1
Muchiri, EM1
Secor, WE1
Karanja, DM1
Friis, H1
Mwaniki, D1
Omondi, B1
Muniu, E1
Thiong'o, F1
Ouma, J2
Geissler, PW1
Michaelsen, KF1
Catton, DG1
Van Schalkwyk, PC1
Bhargava, A1
Jukes, M1
Lambo, J1
Kihamia, CM2
Lorri, W1
Nokes, C1
Drake, L1
Bundy, D1
Brown, M1
Kizza, M1
Watera, C1
Quigley, MA1
Rowland, S1
Hughes, P1
Whitworth, JA1
Koukounari, A1
Kazibwe, F1
Fleming, FM1
Webster, JP1
Stothard, JR1
Muchiri, E1
Mungai, P1
Ndzovu, M1
Tosha, S1
Kitchen, LW1
Guyatt, HL1
Hall, A1
Bundy, DA1
Vounatsou, P1
Tanner, M1
Booth, M1
Latham, MC3
Stephenson, LS3
Kurz, KM3
Kinoti, SN3
Kyobe, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Changes in HIV Viral Load in Patients Undergoing Treatment for Filarial Infection[NCT00344279]1,000 participants (Anticipated)Observational2005-08-08Completed
Can Anthelminthic Treatment Delay the Progression of HIV? Randomised Open-label Trial Testing Presumptive Anthelminthic Treatment on Progression of HIV in ART-naïve HIV-positive Patients in a Rural African Setting With Presumed High Prevalence of Helminth[NCT00817713]295 participants (Actual)Interventional2009-01-31Terminated (stopped due to Terminated prematurely due to recruitment difficulties. Expansion to more study sites not planned.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for praziquantel and Bunostomiasis

ArticleYear
Impact of hookworm infection and deworming on anaemia in non-pregnant populations: a systematic review.
    Tropical medicine & international health : TM & IH, 2010, Volume: 15, Issue:7

    Topics: Adolescent; Adult; Aged; Albendazole; Anemia; Anthelmintics; Child; Child, Preschool; Female; Hemogl

2010
Case studies in international medicine.
    American family physician, 1999, Volume: 59, Issue:11

    Topics: Adolescent; Albendazole; Anti-Infective Agents; Antinematodal Agents; Antiplatyhelmintic Agents; Ant

1999

Trials

12 trials available for praziquantel and Bunostomiasis

ArticleYear
Multiple anthelmintic drug resistant Ancylostoma caninum in foxhounds.
    International journal for parasitology. Drugs and drug resistance, 2023, Volume: 22

    Topics: Ancylostoma; Ancylostomatoidea; Animals; Anthelmintics; Dog Diseases; Dogs; Feces; Hookworm Infectio

2023
The impact of anthelmintic treatment intervention on malaria infection and anaemia in school and preschool children in Magu district, Tanzania: an open label randomised intervention trial.
    BMC infectious diseases, 2015, Mar-20, Volume: 15

    Topics: Albendazole; Ancylostomatoidea; Anemia; Animals; Anthelmintics; Child; Child, Preschool; Female; Hel

2015
Efficacy of emodepside plus praziquantel tablets (Profender tablets for dogs) against mature and immature adult Ancylostoma caninum and Uncinaria stenocephala infections in dogs.
    Parasitology research, 2009, Volume: 105 Suppl 1

    Topics: Administration, Oral; Ancylostoma; Ancylostomatoidea; Animals; Anthelmintics; Depsipeptides; Dog Dis

2009
The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda.
    Parasitology, 2011, Volume: 138, Issue:12

    Topics: Animals; Anthelmintics; Ascariasis; Ascaris lumbricoides; Child, Preschool; Drug Therapy, Combinatio

2011
Treatment with anthelminthics during pregnancy: what gains and what risks for the mother and child?
    Parasitology, 2011, Volume: 138, Issue:12

    Topics: Albendazole; Ancylostomatoidea; Anemia; Animals; Anthelmintics; Benzimidazoles; Birth Weight; Child;

2011
Effects on haemoglobin of multi-micronutrient supplementation and multi-helminth chemotherapy: a randomized, controlled trial in Kenyan school children.
    European journal of clinical nutrition, 2003, Volume: 57, Issue:4

    Topics: Adolescent; Albendazole; Anemia; Animals; Anthelmintics; Ascariasis; Ascaris lumbricoides; Child; Di

2003
The efficacy of two anthelmintics against ascarids and hookworms in naturally infected cats.
    Parasitology research, 2003, Volume: 90 Suppl 3

    Topics: Ancylostomatoidea; Animals; Anthelmintics; Cat Diseases; Cats; Drug Therapy, Combination; Hookworm I

2003
Anthelmintic treatment improves the hemoglobin and serum ferritin concentrations of Tanzanian schoolchildren.
    Food and nutrition bulletin, 2003, Volume: 24, Issue:4

    Topics: Albendazole; Anemia, Iron-Deficiency; Anthelmintics; C-Reactive Protein; Child; Female; Ferritins; H

2003
A school-based approach to the control of urinary schistosomiasis and intestinal helminth infections in children in Matuga, Kenya: impact of a two-year chemotherapy programme on prevalence and intensity of infections.
    Tropical medicine & international health : TM & IH, 1997, Volume: 2, Issue:9

    Topics: Adolescent; Adult; Albendazole; Anthelmintics; Antinematodal Agents; Antiplatyhelmintic Agents; Asca

1997
Metrifonate or praziquantel treatment improves physical fitness and appetite of Kenyan schoolboys with Schistosoma haematobium and hookworm infections.
    The American journal of tropical medicine and hygiene, 1990, Volume: 43, Issue:2

    Topics: Adolescent; Anemia; Anthropometry; Appetite; Child; Follow-Up Studies; Hemoglobins; Hookworm Infecti

1990
Single dose metrifonate or praziquantel treatment in Kenyan children. I. Effects on Schistosoma haematobium, hookworm, hemoglobin levels, splenomegaly, and hepatomegaly.
    The American journal of tropical medicine and hygiene, 1989, Volume: 41, Issue:4

    Topics: Adolescent; Animals; Child; Cross-Sectional Studies; Female; Hemoglobins; Hepatomegaly; Hookworm Inf

1989
Single dose metrifonate or praziquantel treatment in Kenyan children. II. Effects on growth in relation to Schistosoma haematobium and hookworm egg counts.
    The American journal of tropical medicine and hygiene, 1989, Volume: 41, Issue:4

    Topics: Adolescent; Body Height; Body Weight; Child; Female; Hookworm Infections; Humans; Kenya; Male; Paras

1989

Other Studies

15 other studies available for praziquantel and Bunostomiasis

ArticleYear
Efficacy evaluation of anthelmintic products against an infection with the canine hookworm (Ancylostoma caninum) isolate Worthy 4.1F3P in dogs.
    International journal for parasitology. Drugs and drug resistance, 2020, Volume: 13

    Topics: Ancylostomatoidea; Ancylostomiasis; Animals; Anthelmintics; Depsipeptides; Dog Diseases; Dogs; Drug

2020
Once a year school-based deworming with praziquantel and albendazole combination may not be adequate for control of urogenital schistosomiasis and hookworm infection in Matuga District, Kwale County, Kenya.
    Parasites & vectors, 2014, Feb-19, Volume: 7

    Topics: Albendazole; Animals; Child; Cross-Sectional Studies; Drug Therapy, Combination; Feces; Female; Geog

2014
Suppression of basophil histamine release and other IgE-dependent responses in childhood Schistosoma mansoni/hookworm coinfection.
    The Journal of infectious diseases, 2014, Oct-15, Volume: 210, Issue:8

    Topics: Adolescent; Albendazole; Anthelmintics; Child; Histamine; Hookworm Infections; Humans; Immunoglobuli

2014
Profiling Nonrecipients of Mass Drug Administration for Schistosomiasis and Hookworm Infections: A Comprehensive Analysis of Praziquantel and Albendazole Coverage in Community-Directed Treatment in Uganda.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Jan-15, Volume: 62, Issue:2

    Topics: Adolescent; Adult; Albendazole; Animals; Anthelmintics; Chemoprevention; Child; Disease Transmission

2016
The combined effect of the Lymphatic Filariasis Elimination Programme and the Schistosomiasis and Soil-transmitted Helminthiasis Control Programme on soil-transmitted helminthiasis in schoolchildren in Tanzania.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009, Volume: 103, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Child; Drug Therapy, Combination; Elephantiasis, Filarial; Fema

2009
The effect of the community-directed treatment approach versus the school-based treatment approach on the prevalence and intensity of schistosomiasis and soil-transmitted helminthiasis among schoolchildren in Tanzania.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009, Volume: 103, Issue:1

    Topics: Adolescent; Albendazole; Anthelmintics; Child; Community Health Services; Female; Helminthiasis; Hoo

2009
Sequential analysis of helminth egg output in human stool samples following albendazole and praziquantel administration.
    Acta tropica, 2009, Volume: 109, Issue:3

    Topics: Adolescent; Albendazole; Animals; Anthelmintics; Child; Child, Preschool; Feces; Female; Hookworm In

2009
Reduction in hookworm infection after praziquantel treatment among children and young adults in Leyte, the Philippines.
    The American journal of tropical medicine and hygiene, 2010, Volume: 83, Issue:2

    Topics: Adolescent; Adult; Animals; Anthelmintics; Child; Feces; Female; Hookworm Infections; Humans; Longit

2010
Mass drug administration significantly reduces infection of Schistosoma mansoni and hookworm in school children in the national control program in Sierra Leone.
    BMC infectious diseases, 2012, Jan-22, Volume: 12

    Topics: Adolescent; Ancylostomatoidea; Animals; Anthelmintics; Child; Drug Therapy; Feces; Female; Hookworm

2012
Integrated community-directed intervention for schistosomiasis and soil transmitted helminths in western Kenya - a pilot study.
    Parasites & vectors, 2012, Aug-31, Volume: 5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albendazole; Animals; Anthelmintics; Child; Child, Presc

2012
Effects of treatment on IgE responses against parasite allergen-like proteins and immunity to reinfection in childhood schistosome and hookworm coinfections.
    Infection and immunity, 2013, Volume: 81, Issue:1

    Topics: Adolescent; Albendazole; Allergens; Ancylostomatoidea; Animals; Antibodies, Helminth; Antigens, Helm

2013
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
    The Journal of infectious diseases, 2004, Nov-15, Volume: 190, Issue:10

    Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres

2004
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
    The Journal of infectious diseases, 2004, Nov-15, Volume: 190, Issue:10

    Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres

2004
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
    The Journal of infectious diseases, 2004, Nov-15, Volume: 190, Issue:10

    Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres

2004
Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda.
    The Journal of infectious diseases, 2004, Nov-15, Volume: 190, Issue:10

    Topics: Adult; Albendazole; Ancylostomatoidea; Animals; Anthelmintics; CD4 Lymphocyte Count; Disease Progres

2004
Impact of a national helminth control programme on infection and morbidity in Ugandan schoolchildren.
    Bulletin of the World Health Organization, 2007, Volume: 85, Issue:2

    Topics: Adolescent; Albendazole; Ancylostoma; Animals; Anthelmintics; Child; Female; Health Promotion; Helmi

2007
Evaluation of efficacy of school-based anthelmintic treatments against anaemia in children in the United Republic of Tanzania.
    Bulletin of the World Health Organization, 2001, Volume: 79, Issue:8

    Topics: Albendazole; Anemia; Anthelmintics; Child; Cost-Benefit Analysis; Cross-Sectional Studies; Health Pr

2001
Reduction in the prevalence and intensity of hookworm infections after praziquantel treatment for schistosomiasis infection.
    International journal for parasitology, 2002, Volume: 32, Issue:6

    Topics: Adolescent; Ancylostomatoidea; Animals; Anthelmintics; Child; Cote d'Ivoire; Feces; Female; Hookworm

2002