Page last updated: 2024-11-03

praziquantel and Body Weight

praziquantel has been researched along with Body Weight in 24 studies

azinox: Russian drug

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Formulations that can be divided into four parts (to give 150 mg increments) are preferred for children weighing less than 11 kg; the same dosing can be applied with 600 mf praziquantel formulations that can be divided into four quarters or two halves from 11 kg body weight."7.79Practical dosing of praziquantel for schistosomiasis in preschool-aged children. ( Chitsulo, L; Hayes, DJ; Montresor, A; Olliaro, PL; Vaillant, M, 2013)
" Proper dosage adjustment of praziquantel by bodyweight can be difficult to achieve if accurate weighing scales are unavailable."5.39Validating the WHO dose pole in the Philippines for school-based mass drug administration of praziquantel for morbidity control of schistosomiasis. ( Belizario, VY; Chua, PL; Erfe, JM; Naig, JR, 2013)
"The cornerstone of schistosomiasis control is mass praziquantel treatment in high prevalence areas."3.80Dosing of praziquantel by height in sub-Saharan African adults. ( Brigham, T; Chasekwa, B; Humphrey, JH; Mbuya, MN; Palha De Sousa, CA; Prendergast, AJ; Tielsch, JM, 2014)
"Clinical schistosomiasis in endemic countries is treated with a single dose of praziquantel per 40 mg/kg body weight."3.80From a weighing scale to a pole: a comparison of two different dosage strategies in mass treatment of Schistosomiasis haematobium. ( Krantz, I; Mtweve, S; Nordin, P; Poggensee, G, 2014)
"Formulations that can be divided into four parts (to give 150 mg increments) are preferred for children weighing less than 11 kg; the same dosing can be applied with 600 mf praziquantel formulations that can be divided into four quarters or two halves from 11 kg body weight."3.79Practical dosing of praziquantel for schistosomiasis in preschool-aged children. ( Chitsulo, L; Hayes, DJ; Montresor, A; Olliaro, PL; Vaillant, M, 2013)
" For the majority of the patients, the drug was well tolerated and no serious adverse events were noted; however, clinical signs in the form of abdominal pain associated or not with diarrhea and vomiting were noted."2.78[Comparison of the efficacy and safety of praziquantel administered in single dose of 40 versus 60 mg/kg for treating urinary schistosomiasis in Mauritania]. ( Chitsulo, L; Konaté, L; Mamadou, D; Ouldabdallahi, M; Ouldbezeid, M; Ousmane, B, 2013)
" Praziquantel, dosed at 40 milligrams per kilogram bodyweight, is the drug of choice."1.43The Accuracy of Praziquantel Dose Poles for Mass Treatment of Schistosomiasis in School Girls in KwaZulu-Natal, South Africa. ( Aurlund, CG; Baan, M; Gagai, S; Galappaththi-Arachchige, HN; Kjetland, EF; Taylor, M; van Lieshout, L; Vennervald, BJ, 2016)
" Proper dosage adjustment of praziquantel by bodyweight can be difficult to achieve if accurate weighing scales are unavailable."1.39Validating the WHO dose pole in the Philippines for school-based mass drug administration of praziquantel for morbidity control of schistosomiasis. ( Belizario, VY; Chua, PL; Erfe, JM; Naig, JR, 2013)
"4) the pole estimated an acceptable dosage (30-60 mg/kg), a performance statistically similar to that observed in African populations."1.33The WHO dose pole for the administration of praziquantel is also accurate in non-African populations. ( Al-Awaidy, S; Allen, H; Assis, AM; Engels, D; Fenwick, A; Iwata, F; Kabatereine, NB; Montresor, A; Muth, S; Odermatt, P; Raja'a, YA; Savioli, L; Zulkifli, A, 2005)
"Schistosomiasis mansoni is a tropical helminthic disease characterized by parasite egg-induced granulomatous inflammation and cumulative fibrosis."1.32Expression of matrix metalloproteinases and their inhibitors during the resorption of schistosome egg-induced fibrosis in praziquantel-treated mice. ( Boros, DL; Gerard, HC; Hudson, AP; Singh, KP, 2004)
"), each time approximately 5 weeks after dosing with 60-80 OV metacercariae at weeks 0, 8, 16, 24 and 32."1.28Repeated exposure to Opisthorchis viverrini and treatment with the antihelminthic Praziquantel lacks carcinogenic potential. ( Ito, N; Moore, MA; Ruchirawat, S; Thamavit, W, 1992)
"Praziquantel 100 mg/kg was ineffective but 500 mg/kg significantly inhibited growth."1.27Echinococcus multilocularis: in vivo results of therapy with albendazole and praziquantel. ( Morris, DL; Reffin, D; Richards, KS; Taylor, DH, 1988)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's7 (29.17)18.2507
2000's6 (25.00)29.6817
2010's8 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elhenawy, AA1
Ashour, RH1
Nabih, N1
Shalaby, NM1
El-Karef, AA1
Abou-El-Wafa, HS1
Ouldabdallahi, M1
Ousmane, B1
Ouldbezeid, M1
Mamadou, D1
Konaté, L1
Chitsulo, L2
Strobel, H1
de Ponte, M1
Knoppe, TN1
Bhushan, C1
Olliaro, PL1
Vaillant, M1
Hayes, DJ1
Montresor, A3
Erfe, JM1
Belizario, VY1
Chua, PL1
Naig, JR1
Palha De Sousa, CA1
Brigham, T1
Chasekwa, B1
Mbuya, MN1
Tielsch, JM1
Humphrey, JH1
Prendergast, AJ1
Nordin, P1
Poggensee, G1
Mtweve, S1
Krantz, I1
Baan, M1
Galappaththi-Arachchige, HN1
Gagai, S1
Aurlund, CG1
Vennervald, BJ1
Taylor, M1
van Lieshout, L1
Kjetland, EF1
Bonneau, S1
Maynard, L1
Tomczuk, K1
Kok, D1
Eun, HM1
Singh, KP1
Gerard, HC1
Hudson, AP1
Boros, DL1
Odermatt, P1
Muth, S1
Iwata, F1
Raja'a, YA1
Assis, AM1
Zulkifli, A1
Kabatereine, NB1
Fenwick, A1
Al-Awaidy, S1
Allen, H1
Engels, D1
Savioli, L1
Strandgaard, H1
Johansen, MV1
Ørnbjerg, N1
El-Banhawey, MA1
Ashry, MA1
El-Ansary, AK1
Aly, SA1
Idowu, ET1
Mafe, MA1
Appelt, B1
Adewale, B1
Adeneye, AK1
Akinwale, OP1
Manafa, OU1
Akande, DO1
Andrews, P1
Dycka, J1
Frank, G1
Ahmed, SA1
Gad, MZ1
Badawy, AA1
el-Badrawy, NM1
Mansy, SS1
Akl, MM1
Abdel Hady, AM1
Ebeid, FA1
Hassan, MM1
Adnyana, W1
Ladds, PW1
Blair, D1
Thamavit, W3
Moore, MA2
Ruchirawat, S2
Ito, N3
Jack, A1
Bradley, D1
Shirai, T1
Joong, KD1
Hakoi, K1
Pairojkul, C1
Hoshiya, T1
Hasegawa, R1
Stephenson, LS1
Latham, MC1
Kurz, KM1
Kinoti, SN1
Taylor, DH1
Morris, DL1
Richards, KS1
Reffin, D1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sanitation, Hygiene, Infant Nutrition Efficacy Project[NCT01824940]5,280 participants (Actual)Interventional2012-11-30Completed
Prevention of HIV and Improved Diagnosis of Adolescent Genital Disease in Bilharzia Endemic KwaZulu-Natal, South Africa[NCT01154907]6,500 participants (Anticipated)Observational2010-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for praziquantel and Body Weight

ArticleYear
[Comparison of the efficacy and safety of praziquantel administered in single dose of 40 versus 60 mg/kg for treating urinary schistosomiasis in Mauritania].
    Bulletin de la Societe de pathologie exotique (1990), 2013, Volume: 106, Issue:3

    Topics: Adolescent; Anthelmintics; Body Weight; Child; Dose-Response Relationship, Drug; Drug-Related Side E

2013
Comparison of three different treatment schedules for praziquantel (Cestocur®, Bayer) in the treatment of tapeworm infections (Moniezia spp.) and their impact on body weight gains in a German sheep flock.
    Parasitology research, 2013, Volume: 112 Suppl 1

    Topics: Animals; Anthelmintics; Body Weight; Cestoda; Cestode Infections; Feces; Germany; Praziquantel; Shee

2013
Anthelmintic efficacies of a tablet formula of ivermectin-praziquantel on horses experimentally infected with three Strongylus species.
    Parasitology research, 2009, Volume: 105, Issue:3

    Topics: Animals; Anthelmintics; Arteries; Body Weight; Double-Blind Method; Female; Horse Diseases; Horses;

2009
Single dose metrifonate or praziquantel treatment in Kenyan children. II. Effects on growth in relation to Schistosoma haematobium and hookworm egg counts.
    The American journal of tropical medicine and hygiene, 1989, Volume: 41, Issue:4

    Topics: Adolescent; Body Height; Body Weight; Child; Female; Hookworm Infections; Humans; Kenya; Male; Paras

1989

Other Studies

20 other studies available for praziquantel and Body Weight

ArticleYear
Insulin growth factor inhibitor as a potential new anti-schistosoma drug: An in vivo experimental study.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95

    Topics: Animals; Antigens, Helminth; Body Weight; Female; Glucose Transporter Type 4; Homeostasis; Insulin R

2017
Practical dosing of praziquantel for schistosomiasis in preschool-aged children.
    Tropical medicine & international health : TM & IH, 2013, Volume: 18, Issue:9

    Topics: Africa South of the Sahara; Anthelmintics; Body Weight; Brazil; Child; Child, Preschool; Dose-Respon

2013
Validating the WHO dose pole in the Philippines for school-based mass drug administration of praziquantel for morbidity control of schistosomiasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2013, Volume: 107, Issue:10

    Topics: Body Height; Body Weight; Child; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Adm

2013
Dosing of praziquantel by height in sub-Saharan African adults.
    The American journal of tropical medicine and hygiene, 2014, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Anthelmintics; Body Height; Body Weight; Female; Humans; Male; Middle Aged; Prazi

2014
From a weighing scale to a pole: a comparison of two different dosage strategies in mass treatment of Schistosomiasis haematobium.
    Global health action, 2014, Volume: 7

    Topics: Adolescent; Body Height; Body Weight; Child; Drug Dosage Calculations; Female; Humans; Male; Neglect

2014
The Accuracy of Praziquantel Dose Poles for Mass Treatment of Schistosomiasis in School Girls in KwaZulu-Natal, South Africa.
    PLoS neglected tropical diseases, 2016, Volume: 10, Issue:5

    Topics: Adolescent; Body Height; Body Mass Index; Body Weight; Child; Cohort Studies; Cross-Sectional Studie

2016
Expression of matrix metalloproteinases and their inhibitors during the resorption of schistosome egg-induced fibrosis in praziquantel-treated mice.
    Immunology, 2004, Volume: 111, Issue:3

    Topics: Animals; Anthelmintics; Body Weight; Cell Count; Cells, Cultured; Collagen; Cytokines; Female; Gene

2004
The WHO dose pole for the administration of praziquantel is also accurate in non-African populations.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2005, Volume: 99, Issue:1

    Topics: Adolescent; Adult; Anthelmintics; Body Height; Body Weight; Child; Child, Preschool; Drug Administra

2005
Field testing of the WHO dose pole for administration of praziquantel in the treatment of opisthorchiasis in Lao PDR.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:11

    Topics: Adolescent; Adult; Aged; Anthelmintics; Body Height; Body Weight; Child; Dose-Response Relationship,

2007
Effect of Curcuma longa or parziquantel on Schistosoma mansoni infected mice liver--histological and histochemical study.
    Indian journal of experimental biology, 2007, Volume: 45, Issue:10

    Topics: Alkaline Phosphatase; Animals; Body Weight; Curcuma; Liver Diseases; Male; Mice; Organ Size; Phytoth

2007
Height as a substitute for weight for estimating praziquantel dosage.
    World health & population, 2007, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Anthelmintics; Body Height; Body Weight; Child; Child, Preschool; Dose-Response R

2007
Effect of praziquantel on clinical-chemical parameters in healthy and schistosome-infected mice.
    Annals of tropical medicine and parasitology, 1980, Volume: 74, Issue:2

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Cell Count;

1980
Effect of schistosomal infection and its treatment on some key enzymes of glucose metabolism in mice livers.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:12

    Topics: Animals; Body Weight; Citric Acid Cycle; Female; Glucose; Glycolysis; Liver; Liver Glycogen; Male; M

1995
Evaluation of colchicine with or without praziquantel therapy in the control of hepatic fibrosis in murine schistosomiasis.
    Pharmacological research, 1996, Volume: 33, Issue:6

    Topics: Animals; Body Weight; Colchicine; Collagen; Connective Tissue; Female; Liver Cirrhosis, Experimental

1996
Efficacy of praziquantel in the treatment of green sea turtles with spontaneous infection of cardiovascular flukes.
    Australian veterinary journal, 1997, Volume: 75, Issue:6

    Topics: Administration, Oral; Alanine Transaminase; Animals; Antiplatyhelmintic Agents; Aspartate Aminotrans

1997
Lack of modulation effects of praziquantel on DMN-induced lesion development in the Syrian hamster liver.
    Cancer letters, 1992, Jan-31, Volume: 61, Issue:3

    Topics: Animals; Body Weight; Carcinoma, Hepatocellular; Cricetinae; Dimethylnitrosamine; Drug Interactions;

1992
Scales modified for dose determination in population-based chemotherapy.
    Lancet (London, England), 1991, Jan-26, Volume: 337, Issue:8735

    Topics: Adult; Body Weight; Child, Preschool; Community Health Workers; Drug Administration Schedule; Evalua

1991
Promotion of rat hepatocarcinogenesis by praziquantel.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:10

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carcinogens; Diethylnitrosa

1991
Repeated exposure to Opisthorchis viverrini and treatment with the antihelminthic Praziquantel lacks carcinogenic potential.
    Carcinogenesis, 1992, Volume: 13, Issue:2

    Topics: Animals; Body Weight; Cricetinae; Liver Diseases, Parasitic; Liver Neoplasms, Experimental; Male; Me

1992
Echinococcus multilocularis: in vivo results of therapy with albendazole and praziquantel.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:4

    Topics: Albendazole; Animals; Anthelmintics; Arvicolinae; Benzimidazoles; Body Weight; Echinococcosis; Echin

1988