Page last updated: 2024-08-23

pravastatin and Reperfusion Injury

pravastatin has been researched along with Reperfusion Injury in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (71.43)29.6817
2010's3 (21.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Chen, ZL; Deng, F; Hu, JJ; Li, C; Lin, ZB; Liu, KX; Liu, WF; Liu, Y; Luo, SD; Sun, QS; Yan, ZZ; Yang, X; Yao, ZW; Zhao, BC1
Chen, J; Li, H; Li, N; Liu, C; Sun, J; Wang, C1
Barron, FE; Burridge, PW; Churko, JM; Diecke, S; Gold, JD; Gu, M; He, C; Hu, S; Kooreman, NG; Lee, J; Mordwinkin, NM; Ong, SG; Wu, H; Wu, JC1
Burne-Taney, MJ; Ikeda, M; Ito, K; Kumagai, K; Mori, M; Rabb, H; Sharyo, S; Uchida, K; Yokota-Ikeda, N1
Haslinger-Löffler, B1
Honda, Y; Honjo, M; Kiryu, J; Nishijima, K; Sawamura, T; Tanihara, H; Yue, BY1
Bharwani, S; Grisham, MB; Harada, H; Hines, IN; Hoffman, JM; Lefer, DJ; Pavlick, KP; Wolf, RE1
Chandler, JR; Dillon, JP; Laing, AJ; McGuinness, A; Redmond, HP; Wang, JH1
Dichgans, M; Hamann, GF; Trinkl, A; Vosko, MR; Wunderlich, N1
Abolhassani, F; Ebrahimnejad, M; Jahanzad, I; Nouri, M; Pourabbasi, A1
Agardh, CD; Agardh, E; Gustavsson, C; Hagert, P1
Bouchier-Hayes, DJ; Chen, G; Joyce, M; Kelly, CJ1
Bouchier-Hayes, D; Chen, G; Joyce, M; Kelly, C; Leahy, A; Winter, D1
Do, GM; Kwon, O; Lim, EJ; Shin, JH1

Trials

1 trial(s) available for pravastatin and Reperfusion Injury

ArticleYear
Pravastatin attenuates lower torso ischaemia-reperfusion-induced lung injury by upregulating constitutive endothelial nitric oxide synthase.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2001, Volume: 21, Issue:4

    Topics: Analysis of Variance; Animals; Blotting, Western; Bronchoalveolar Lavage Fluid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung; Male; Neutrophils; Nitric Oxide Synthase; Peroxidase; Pravastatin; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Up-Regulation

2001

Other Studies

13 other study(ies) available for pravastatin and Reperfusion Injury

ArticleYear
Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Immunity, Innate; Interleukin-1 Receptor-Like 1 Protein; Interleukin-13; Interleukin-33; Intestinal Diseases; Lymphocytes; Male; Mice; Mice, Knockout; Pravastatin; Reperfusion Injury

2021
Pravastatin Decreases Infarct Size Induced by Coronary Artery Ischemia/Reperfusion with Elevated eNOS Expression in Rats.
    International heart journal, 2018, Volume: 59, Issue:1

    Topics: Animals; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; Myocardium; Nitric Oxide Synthase Type III; Pravastatin; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA

2018
Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism.
    European heart journal, 2015, Apr-01, Volume: 36, Issue:13

    Topics: Analysis of Variance; Animals; Apoptosis; Cell Differentiation; Diet, High-Fat; Endothelial Cells; Enzyme Inhibitors; Fibroblasts; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Induced Pluripotent Stem Cells; Injections, Intramuscular; Ischemia; Mice, Inbred C57BL; Muscle, Skeletal; Muscular Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Oxidative Stress; Pravastatin; Proto-Oncogene Proteins c-akt; Random Allocation; Reperfusion Injury; Signal Transduction

2015
Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway.
    Kidney international, 2008, Volume: 74, Issue:5

    Topics: Acute Kidney Injury; Animals; Apolipoproteins E; Cholesterol; Creatinine; Enzyme Inhibitors; Farnesyltranstransferase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Kidney; Male; Methionine; Mevalonic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Pravastatin; Reperfusion Injury; Terpenes

2008
Multiple effects of HMG-CoA reductase inhibitors (statins) besides their lipid-lowering function.
    Kidney international, 2008, Volume: 74, Issue:5

    Topics: Animals; Cholesterol; Disease Models, Animal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Inflammation; Interleukin-6; Kidney; Mice; Pravastatin; Reperfusion Injury

2008
Statin inhibits leukocyte-endothelial interaction and prevents neuronal death induced by ischemia-reperfusion injury in the rat retina.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2002, Volume: 120, Issue:12

    Topics: Acridine Orange; Animals; Apoptosis; Cell Adhesion; Endothelium, Vascular; Fluorescent Dyes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Situ Nick-End Labeling; Intercellular Adhesion Molecule-1; Leukocytes; Male; Neurons; Neuroprotective Agents; P-Selectin; Polymerase Chain Reaction; Pravastatin; Pyridines; Rats; Rats, Long-Evans; Reperfusion Injury; Retinal Diseases; Retinal Vessels; RNA, Messenger

2002
Sexual dimorphism in reduced-size liver ischemia and reperfusion injury in mice: role of endothelial cell nitric oxide synthase.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Jan-21, Volume: 100, Issue:2

    Topics: Animals; Female; Ischemia; Liver; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pravastatin; Reperfusion Injury; Sex Characteristics

2003
Pravastatin attenuates tourniquet-induced skeletal muscle ischemia reperfusion injury.
    Acta orthopaedica, 2006, Volume: 77, Issue:1

    Topics: Administration, Oral; Animals; Anticholesteremic Agents; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Muscle, Skeletal; Pravastatin; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tourniquets

2006
Pravastatin reduces microvascular basal lamina damage following focal cerebral ischemia and reperfusion.
    The European journal of neuroscience, 2006, Volume: 24, Issue:2

    Topics: Animals; Basement Membrane; Biomarkers; Blood-Brain Barrier; Cerebral Arterial Diseases; Cerebral Arteries; Cerebral Infarction; Collagen Type IV; Disease Models, Animal; Down-Regulation; Hemoglobins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperemia; Ischemic Attack, Transient; Male; Microcirculation; Pravastatin; Rats; Rats, Wistar; Reperfusion Injury

2006
Pravastatin prevents ischemia-reperfusion injury in rat sciatic nerve.
    Surgical neurology, 2006, Volume: 66, Issue:3

    Topics: Animals; Axons; Cytoprotection; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Male; Neuroprotective Agents; Oxidative Stress; Peripheral Nerves; Pravastatin; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sciatic Neuropathy; Time Factors; Treatment Outcome; Wallerian Degeneration

2006
Inflammatory markers in nondiabetic and diabetic rat retinas exposed to ischemia followed by reperfusion.
    Retina (Philadelphia, Pa.), 2008, Volume: 28, Issue:4

    Topics: Animals; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Docosahexaenoic Acids; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Pravastatin; Rats; Rats, Wistar; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2008
Pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, attenuates renal injury in an experimental model of ischemia-reperfusion.
    The Journal of surgical research, 2001, Volume: 101, Issue:1

    Topics: Animals; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Kidney; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pravastatin; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury

2001
Protective effects of Acanthopanax divaricatus vat. albeofructus and its active compound on ischemia-reperfusion injury of rat liver.
    Biochemical and biophysical research communications, 2013, Mar-22, Volume: 432, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Eleutherococcus; Furans; Glucosides; Ischemia; L-Lactate Dehydrogenase; Lignans; Liver; Male; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2013