Page last updated: 2024-08-23

pravastatin and Ischemia

pravastatin has been researched along with Ischemia in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's10 (66.67)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Banek, CT; Bauer, AJ; Capoccia, S; Gilbert, JS; Gillham, H; Needham, K; Regal, JF1
Fukui, K; Hibi, K; Kunishima, T; Michishita, I; Morino, Y; Nozue, T; Onishi, Y; Sozu, T; Takeyama, Y; Terashima, M; Tohyama, S; Umezawa, S; Yamamoto, S; Yamauchi, T1
Barron, FE; Burridge, PW; Churko, JM; Diecke, S; Gold, JD; Gu, M; He, C; Hu, S; Kooreman, NG; Lee, J; Mordwinkin, NM; Ong, SG; Wu, H; Wu, JC1
Hikita, Y; Iwao, H; Izumi, Y; Kusakabe, H; Miura, K; Muro, T; Nakamura, Y; Nakao, T; Shiota, M; Yoshiyama, M1
Bharwani, S; Grisham, MB; Harada, H; Hines, IN; Hoffman, JM; Lefer, DJ; Pavlick, KP; Wolf, RE1
Domínguez, J; Schultz, M1
Czosnyka, M; Kirkpatrick, PJ; Pickard, JD; Richards, H; Tseng, MY1
Damkier, P; Hallas, J; Korsholm, L; Kristensen, SR; Mickley, H; Poulsen, TS; Vinholt, P1
Chen, J; Hashimoto, K; Mitsui, K; Nagasawa, Y; Shen, H; Tsurugi, K1
Campesi, I; Emanueli, C; Gadau, S; Kraenkel, N; Madeddu, P; Meloni, M; Monopoli, A; Ongini, E1
Fujii, T; Kuwano, H; Onimaru, M; Sueishi, K; Yonemitsu, Y1
Ichihara, K; Nakai, T; Satoh, K1
Diamond, RH; Forman, LM; Simmons, DA1
Bouchier-Hayes, D; Chen, G; Joyce, M; Kelly, C; Leahy, A; Winter, D1
Do, GM; Kwon, O; Lim, EJ; Shin, JH1

Trials

2 trial(s) available for pravastatin and Ischemia

ArticleYear
C-reactive protein and future cardiovascular events in statin-treated patients with angina pectoris: the extended TRUTH study.
    Journal of atherosclerosis and thrombosis, 2013, Volume: 20, Issue:9

    Topics: Aged; Angina Pectoris; C-Reactive Protein; Cardiovascular Diseases; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Japan; Male; Middle Aged; Myocardial Infarction; Plaque, Atherosclerotic; Pravastatin; Prospective Studies; Quinolines; Regression Analysis; Risk Factors; Treatment Outcome; Ultrasonography, Interventional

2013
Effects of acute treatment with pravastatin on cerebral vasospasm, autoregulation, and delayed ischemic deficits after aneurysmal subarachnoid hemorrhage: a phase II randomized placebo-controlled trial.
    Stroke, 2005, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Aneurysm; Ischemia; Ischemic Attack, Transient; Male; Middle Aged; Odds Ratio; Placebos; Pravastatin; Regression Analysis; Subarachnoid Hemorrhage; Time Factors; Ultrasonography, Doppler, Transcranial; Vasospasm, Intracranial

2005

Other Studies

13 other study(ies) available for pravastatin and Ischemia

ArticleYear
Pravastatin attenuates hypertension, oxidative stress, and angiogenic imbalance in rat model of placental ischemia-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:5

    Topics: Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Ischemia; Neovascularization, Physiologic; Oxidative Stress; Placenta; Pravastatin; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Trophoblasts; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1

2013
Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism.
    European heart journal, 2015, Apr-01, Volume: 36, Issue:13

    Topics: Analysis of Variance; Animals; Apoptosis; Cell Differentiation; Diet, High-Fat; Endothelial Cells; Enzyme Inhibitors; Fibroblasts; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Induced Pluripotent Stem Cells; Injections, Intramuscular; Ischemia; Mice, Inbred C57BL; Muscle, Skeletal; Muscular Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Oxidative Stress; Pravastatin; Proto-Oncogene Proteins c-akt; Random Allocation; Reperfusion Injury; Signal Transduction

2015
Pravastatin accelerates ischemia-induced angiogenesis through AMP-activated protein kinase.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:8

    Topics: Animals; Blotting, Western; Capillaries; Cell Movement; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hindlimb; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Laser-Doppler Flowmetry; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Phosphorylation; Pravastatin

2009
Sexual dimorphism in reduced-size liver ischemia and reperfusion injury in mice: role of endothelial cell nitric oxide synthase.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Jan-21, Volume: 100, Issue:2

    Topics: Animals; Female; Ischemia; Liver; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pravastatin; Reperfusion Injury; Sex Characteristics

2003
Pravastatin decreases cold ischemia--but not alloantigen-dependent transplant arteriosclerosis.
    Transplantation proceedings, 2003, Volume: 35, Issue:8

    Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Cold Temperature; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Isoantigens; Male; Pravastatin; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous; Transplantation, Isogeneic; Tunica Intima

2003
The antiplatelet effect of clopidogrel is not attenuated by statin treatment in stable patients with ischemic heart disease.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:2

    Topics: Aged; Atorvastatin; Blood Platelets; Cholesterol, LDL; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Heart Diseases; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Pyrroles; Simvastatin; Ticlopidine; Time Factors; Wound Healing

2005
Pravastatin inhibits arrhythmias induced by coronary artery ischemia in anesthetized rats.
    Journal of pharmacological sciences, 2007, Volume: 103, Issue:3

    Topics: Administration, Oral; Anesthesia; Animals; Arrhythmias, Cardiac; Coronary Vessels; Dose-Response Relationship, Drug; Drug Administration Schedule; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl CoA Reductases; Indoles; Ischemia; Male; Peroxidase; Pravastatin; Rats; Rats, Sprague-Dawley

2007
Nitropravastatin stimulates reparative neovascularisation and improves recovery from limb Ischaemia in type-1 diabetic mice.
    British journal of pharmacology, 2007, Volume: 150, Issue:7

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Pravastatin

2007
Statins restore ischemic limb blood flow in diabetic microangiopathy via eNOS/NO upregulation but not via PDGF-BB expression.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6

    Topics: Animals; Becaplermin; Blood Glucose; Cells, Cultured; Cholesterol, LDL; Combined Modality Therapy; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Foot; Enzyme Inhibitors; Genetic Therapy; Glycation End Products, Advanced; Hindlimb; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet-Derived Growth Factor; Pravastatin; Proto-Oncogene Proteins c-sis; Quinolines; Regional Blood Flow; Signal Transduction; Time Factors; Up-Regulation

2008
Influence of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on mitochondrial respiration in rat liver during ischemia.
    European journal of pharmacology, 1994, Aug-03, Volume: 270, Issue:4

    Topics: Adenosine Diphosphate; Animals; Cell Fractionation; Glutamic Acid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Liver; Lovastatin; Male; Mitochondria, Liver; Oxygen Consumption; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Succinates

1994
Hepatic failure in a patient taking rosiglitazone.
    Annals of internal medicine, 2000, Jan-18, Volume: 132, Issue:2

    Topics: Aged; Combined Modality Therapy; Coronary Disease; Diabetes Mellitus, Type 2; Drug Interactions; Humans; Hypoglycemic Agents; Ischemia; Liver; Liver Failure; Male; Monitoring, Physiologic; Pravastatin; Rosiglitazone; Thiazoles; Thiazolidinediones; Verapamil

2000
Pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, attenuates renal injury in an experimental model of ischemia-reperfusion.
    The Journal of surgical research, 2001, Volume: 101, Issue:1

    Topics: Animals; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Kidney; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pravastatin; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury

2001
Protective effects of Acanthopanax divaricatus vat. albeofructus and its active compound on ischemia-reperfusion injury of rat liver.
    Biochemical and biophysical research communications, 2013, Mar-22, Volume: 432, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Eleutherococcus; Furans; Glucosides; Ischemia; L-Lactate Dehydrogenase; Lignans; Liver; Male; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2013