Page last updated: 2024-08-23

pravastatin and Hypercholesterolemia

pravastatin has been researched along with Hypercholesterolemia in 680 studies

Research

Studies (680)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (1.18)	18.7374
1990's	295 (43.38)	18.2507
2000's	301 (44.26)	29.6817
2010's	73 (10.74)	24.3611
2020's	3 (0.44)	2.80

Authors

Authors	Studies
Buckett, L; Davidson, R; Holdgate, G; McCormick, A; McTaggart, F; Schneck, D; Smith, G; Warwick, M	1
Askew, V; Auerbach, B; Bainbridge, G; Caspers, N; Choi, C; Dillon, L; Hanselman, JC; Harris, MS; Hutchings, R; Kowala, M; Larsen, SD; Lin, Z; Lu, GH; Park, W; Pavlovsky, A; Pfefferkorn, JA; Robertson, A; Sekerke, C; Tait, BD	1
Askew, V; Atkinson, K; Auerbach, B; Bakker-Arkema, R; Barclay, P; Bi, YA; Boustany, C; Bowles, DM; Boyles, DC; Bush, MR; Cheng, XM; Chupka, J; Dillon, L; Duignan, DB; El-Kattan, A; Erasga, N; Feng, B; Goosen, TC; Hanselman, JC; Hutchings, R; Kennedy, R; Kimoto, E; Kindt, E; Kowala, M; Lai, Y; Larsen, SD; Le, V; Lee, C; Lin, Z; Litchfield, J; Lu, G; Mandema, JW; Milad, M; Olsen, K; Pfefferkorn, JA; Robertson, A; Sahasrabudhe, V; Scialis, R; Sekerke, C; Tait, BD; Trivedi, BK	1
Favero, BC; García-Arevalo, M; Gomes-Marcondes, MCC; Lorza-Gil, E; Oliveira, HCF	1
Abd Allah, EF; Charan, J; Hashem, A; Jaipal, N; Kashyap, P; Kumar, S; Ram, H; Siddaiah, CN; Singh, BP; Tabassum, B; Tripathi, R	1
Kang, HT; Kim, HS; Kim, J; Lee, JW; Yang, W	1
Anagnostis, P; Bosdou, JK; Goulis, DG; Hatzimouratidis, K; Ioannidou, PG; Mikhailidis, DP; Papanikolaou, D	1
Blaum, CS; Davis, BR; Han, BH; Pervin, H; Piller, LB; Pressel, SL; Sutin, D; Williamson, JD	1
Burns, RB; Graham, K; Reynolds, EE; Sawhney, MS	1
Chen, X; Li, Y; Lin, L; Wang, S; Zhang, H	1
Clifton, J; Lang, T; Neher, J; Safranek, S	1
Abdel-Rahman, S; Gaedigk, A; Gaedigk, R; Kauffman, R; Leeder, JS; Raghuveer, G; Staggs, VS; Van Haandel, L; Wagner, JB	1
Baronio, F; Biagi, C; Borghi, C; Cicero, AFG; D'Addato, S; Fogacci, F; Palmisano, S	1
Hori, E; Imaeda, K; Kikuchi, C; Matsunaga, T; Okayama, N; Suzuki, T	1
Daida, H; Hata, M; Kaku, K; Kawamori, R; Kishimoto, J; Kurabayashi, M; Masuda, I; Nohara, R; Sakuma, I; Yamazaki, T; Yokoi, H; Yoshida, M	2
Chang, SA; Kim, JH; Lee, JM; Lee, MR; Lee, SS; Shin, JA; Yoon, KH; You, SJ	1
Nakagami, T; Nishimura, R; Sone, H; Tajima, N	1
Cagampang, FR; Elahi, MM; Hanson, MA; Ohri, SK	1
Choi, H; Han, SH; Koh, KK; Lee, K; Lee, Y; Lim, S; Oh, PC; Quon, MJ; Sakuma, I; Shin, EK	1
Bloch, MJ	1
Baimbridge, C; Ciocon, JO; Cuyjet, AB; Dart, RA; Davis, BR; Einhorn, PT; Ford, CE; Gordon, D; Hartney, TJ; Holtzman, J; Julian Haywood, L; Margolis, KL; Mathis, DE; Oparil, S; Probstfield, JL; Simpson, LM; Stokes, JD; Wiegmann, TB; Williamson, JD	2
Catapano, AL; Corrao, G; Ibrahim, B; Mancia, G; Merlino, L; Nicotra, F; Pasini, TS; Zambon, A	1
Agarwal, V; Bangalore, S; Messerli, FH	1
Daida, H; Kitagawa, Y; Matsushita, Y; Sugihara, M; Teramoto, T	1
Matsuyama, Y; Ohashi, Y; Taguri, M	1
Matsuyama, Y; Ohashi, Y; Shinozaki, T	1
Hu, MY; Jia, LL; Li, F; Liu, C; Liu, L; Liu, XD; Xu, D; Yang, Y; Zhang, M; Zhong, ZY	1
Ahn, CW; Cha, BS; Cho, Y; Choe, E; Choi, Y; Kang, ES; Lee, HC; Lee, YH; Seo, JW; Wang, HJ; Yun, Y	1
Ebisawa, S; Ikeda, U; Izawa, A; Kagoshima, M; Kashima, Y; Kitabayashi, H; Koyama, J; Miura, T; Miyashita, Y; Sakurai, S; Tomita, T; Yamamoto, H	1
Dohi, T	1
Einecke, D	2
Kietsiriroje, N; Leelawattana, R	1
Al-Badriyeh, D; Al-Khal, A; Alabbadi, I; Fahey, M; Zaidan, M	1
Bachoumas, K; Fiancette, M; Lacherade, JC; Lascarrou, JB; Leclair, F; Reignier, J	1
Anzalone, DA; Cain, VA; Friday, KE; Lewis, SJ; Welty, FK	1
Baker, R; Jackson, D	1
Ford, I; McCowan, C; Murray, H; Packard, CJ	1
Catharino, RR; Ferreira, MS; Lorza-Gil, E; Oliveira, HC; Rentz, T; Salerno, AG; Vettorazzi, JF; Wanschel, AC	1
Robb-Nicholson, C	1
Aldea, P; de Hoz, R; Fernández-Navarro, J; Gallego, BI; Ramírez, AI; Ramírez, JM; Rojas, B; Salazar, JJ; Tejerina, T; Triviño, A	1
del Sol, AI; Nanayakkara, PW	1
Kurata, H; Kushiro, T; Mizuno, K; Nakamura, H; Nakaya, N; Ohashi, Y; Tajima, N; Teramoto, T; Uchiyama, S	1
Baimbridge, C; Barzilay, J; Basile, JN; Davis, BR; Henriquez, MA; Huml, A; Kopyt, N; Louis, GT; Pressel, SL; Rahman, M; Rosendorff, C; Sastrasinh, S; Stanford, C	1
Beamer, B; Costa-Scharplatz, M; Frial, T; Gandhi, S; Ramanathan, K	1
Elsais, A; Kerty, E; Lund, C	1
Ishikawa, T; Kushiro, T; Mizuno, K; Nakamura, H; Nakaya, N; Ohashi, Y; Tajima, N; Teramoto, T; Uchiyama, S	1
Avello L, M; Bravo D, M; Calvo M, C; Mennickent C, S	1
Maitland-van der Zee, AH; Peters, B	1
Han, SH; Kim, SJ; Koh, KK; Lee, Y; Park, JB; Quon, MJ; Shin, EK	1
Kadonosono, K; Takano, T; Tanaka, S; Terauchi, Y; Yamakawa, T	1
Calza, L; Chiodo, F; Colangeli, V; Manfredi, R; Pavoni, M; Pocaterra, D	1
Bao-Feng, Y; Ben-Zhi, C; Jing, A; Li-Mei, Z; Yan-Jie, L; Yong, Z	1
Glueck, CJ; Goldenberg, N; Khan, NA; Rawal, B; Wang, P; Yeramaneni, S	1
Hanson, M; Hoffman, R; Strony, J; Veltri, E	1
Huang, CN; Lee, IT; Lee, WJ; Ou, HC; Sheu, WH	1
Nakamura, H	2
Kushiro, T; Mizuno, K; Nakamura, H; Nakaya, N; Ohashi, Y; Tajima, N; Teramoto, T; Uchiyama, S	2
Hayashi, T; Ijiri, Y; Iwamoto, A; Kato, R; Kozu, C; Nishide, M; Suzuki, K; Tanaka, K; Urashima, K	1
Kai, T; Kanamasa, K	1
Bailey, KM; Balmforth, AJ; Hall, AS; Romaine, SP	1
Alcalá, A; Egido, J; Farkouh, ME; Gómez-Huelgas, R; Jansen, S; Pérez, O; Téllez, T	1
Dunn, K; Einhorn, PT; Ford, CE; Gordon, DJ; Margolis, KL; Probstfield, JL; Simpson, LM; Williamson, JD	1
de Hoz, R; Mendez, T; Ramírez, AI; Ramírez, JM; Raposo, R; Redondo, A; Rojas, B; Salazar, JJ; Tejerina, T; Triviño, A	1
King, S; Superko, HR	1
Bilo, G; Crepaldi, G; Giuliano, A; Mancia, G; Parati, G; Revera, M; Veglia, F; Zanchetti, A	1
Watson, KE	1
Butani, L; Lau, KK; Perez, RV; Tancredi, DJ	1
Mizuno, K; Nakamura, H; Nakaya, N; Ohashi, Y; Teramoto, T; Yokoyama, S	1
Berthold, HK; Gouni-Berthold, I; Sudhop, T; von Bergmann, K	1
Acharjee, S; Cannon, CP	1
Arranz Martínez, E; Gordillo López, FJ; Hermosa Hernán, JC; Ruiz García, A	1
Betteridge, J	1
Cobbe, S; Ford, I; Logue, J; Macfarlane, P; Murray, HM; Packard, C; Sattar, N; Shepherd, J; Welsh, P	1
Kadonosono, K; Kaneko, T; Kawaguchi, J; Morita, S; Shigematu, E; Terauchi, Y; Yamakawa, T	1
Caretta, G; Dei Cas, L; Della Pina, P; Gorga, E; Madureri, A; Raddino, R	1
Nakagami, T; Nishimura, R; Ohashi, Y; Sone, H; Tajima, N	1
Freeman, MR; Solomon, KR	1
Hirahara, K; Mizuno, K; Mizutani, M; Nakamura, H; Nakaya, N; Ohashi, Y; Teramoto, T; Yokoyama, S	1
Daida, H; Kitagawa, Y; Teramoto, T	1
Kubota, Y; Mizuno, K; Nakamura, H; Nakaya, N; Ohashi, Y; Takahashi, S; Teramoto, T; Ueki, A; Yokoyama, S	1
Akao, H; Buckley, BM; de Craen, AJ; Ford, I; Jukema, JW; Kajinami, K; Packard, C; Polisecki, E; Robertson, M; Schaefer, EJ; Shepherd, J; Trompet, S; Westendorp, RG	2
Choi, H; Han, SH; Koh, KK; Lee, K; Quon, MJ; Sakuma, I; Shin, EK	1
Anastasiou-Nana, M; Andreadou, I; Farmakis, D; Iliodromitis, EK; Kremastinos, DT; Papalois, A; Papapetropoulos, A; Prokovas, E; Sigala, F; Spyridaki, K; Zoga, A	1
Choudhury, RP; Iacob, AO	1
Arca, M; Budal, S; Degli Esposti, E; Degli Esposti, L; Sangiorgi, D; Vigna, GB	1
Biro, S; Hata, S; Kono, S; Oshima, Y; Otonari, T; Saikawa, T; Sasaki, J; Sawayama, Y	1
Budinski, D; Gosho, M; Hounslow, N; Stender, S	1
Catapano, AL; Garlaschelli, K; Grigore, L; Norata, GD; Pirillo, A; Raselli, S; Redaelli, L	1
Hirayama, A; Nagao, K; Tani, S	1
Cobbe, S; Di Angelantonio, E; Doolin, O; Ford, I; Gudnason, V; Macfarlane, P; Packard, C; Sattar, N; Welsh, P; Willeit, P	1
Devi, K; Ghodke, RM; Tour, N	1
Hildebrandt, GC; Panu, LD; Shahan, JL	1
Fenger, M	1
Buss, NE; Gazzard, BG; Moyle, GJ	1
Betz, W; Coigniez, P; Devroey, D; Lauwers, R; Velkeniers, B	1
Amore, C; Angelini, A; Baccante, G; Cuccurullo, F; di Castelnuovo, A; Di Febbo, C; Di Nisio, M; Donati, M; Iacoviello, L; Porreca, E	1
Blauw, GJ; Bollen, EL; Buckley, B; Cobbe, SM; Ford, I; Gaw, A; Houx, PJ; Hyland, M; Jukema, W; Kamper, AM; MacFarlane, PW; Meinders, AE; Murphy, MB; Norrie, J; Packard, CJ; Perry, IJ; Shepherd, J; Stott, DJ; Sweeney, BJ; Twomey, C; Westendorp, RG	1
Saito, Y; Sasaki, N; Shinomiya, M; Shirai, K; Yoshida, S	1
Kantola, I; Porela, P	1
Ahn, C; Aronow, WS	1
Shah, PK	1
Carlsson, CM; Carnes, M; McBride, PE; Papcke-Benson, K; Stein, JH	1
Gross, W; Harder, S; Krell, B; März, W; Merz, M; Park, JW; Schüler, S; Seidel, D; Siekmeier, R	1
Meadows, SE; Stevermer, JJ	1
Chmielewski, M; Rutkowski, B; Zdrojewski, Z	1
Gaw, A; Shepherd, J	1
Chou, TF; Lee, TM; Tsai, CH	1
Alcalá, A; Morell, M; Rius, F	1
Pasternak, RC	1
Bays, HE; Brown, WV; Chitra, R; Hassman, DR; Hutchinson, H; McKenney, J; Miller, E	1
Frolkis, JP; Minor, S; Nambi, V; Pearce, GL; Sprecher, DL	1
Angori, P; Auteri, A; Bova, G; Bruni, F; Cercignani, M; Palazzuoli, A; Pasqui, AL; Pastorelli, M; Puccetti, L	1
Arnesen, H; Eid, HM; Eritsland, J; Larsen, J; Seljeflot, I	1
Ando, H; Kobayashi, K; Misu, H; Osawa, K; Takamura, T	1
Derhaschnig, U; Dorner, GT; Jilma, B; Joukhadar, C; Petternel, V; Rassoul, F; Richter, V; Wagner, OF; Wolzt, M	1
Ferrières, J	1
Branchi, A; Fiorenza, AM; Sommariva, D	1
Krane, V; Wanner, C	1
Berry, K; Burger, HG; Davis, SR; Goldstat, R; Koch, K; Meredith, I; Newman, A	1
Kulbertus, H; Scheen, AJ	3
Boh, M; Keber, I; Sebestjen, M	1
Bouzamondo, A; Corvol, JC; Hulot, JS; Lechat, P; Sanchez, P; Sirol, M	1
Leoh, TH; Lo, YL; Loh, LM; Tan, CE	1
Bortolini, EB; Brüch, RS; Buffé, F; Mastalir, ET; Moriguchi, EH; Portal, VL; Rodrigues, R; Schio, S; Vieira, J	1
Blasetto, JW; Brown, WV; Chitra, R; Raza, A; Stein, EA	1
Barter, P; Hunninghake, DB; Hutchinson, HG; McKenney, JM; Shepherd, J	1
Caplan, RJ; Davidson, MH; Pears, JS; Rader, DJ	1
Fuller, S; Gillen, D; Lacey, L; Marriott, J; Wilson, K	1
McBurney, CR; Smith, DG	1
Fischer, S; Haverich, A; Strüber, M; Walles, T; Wilhelmi, M; Winterhalter, M; Zuk, J	1
Bays, HE; Rosenson, RS	1
Baztán, JJ; Hornillos, M; Rodríguez-Mañas, L	1
Hassman, D; LeBeaut, A; Lipetz, R; Lipka, L; Melani, L; Mills, R; Mukhopadhyay, P; Suresh, R; Veltri, E	1
Atarashi, K; Goto, A; Hirata, Y; Ishiyama, A; Minami, M; Omata, M	1
Anagnostopoulos, GK; Arvanitidis, D; Kostopoulos, P; Margantinis, G; Tsiakos, S	1
Butani, L; Makker, SP; Pai, MV	1
Broncel, M; Chojnowska-Jezierska, J; Franiak, I; Koter, M	1
Jiménez, J; Lahoz, C; López-Pastor, A; Mostaza, JM; Peña, R; Pintó, X; Subirats, E; Taboada, M	1
Arakawa, K; Iwashita, M; Kono, S; Matsushita, Y; Sasaki, J	1
Chirkov, YY; Horowitz, JD; Prideaux, RM; Stepien, JM; Willoughby, SR	1
Bays, HE; Blasetto, JW; Cain, VA; Davidson, MH; Jones, PH; McKenney, JM; Miller, E; Stein, EA	1
Lama, A	1
Averkov, OV; Deev, AD; Gratsianskiĭ, NA; Pokrovskaia, EV; Vaulin, NA	1
Aronow, WS	1
Rosenson, RS; Tangney, CC; Wolff, D	1
Origasa, H; Yokoyama, M	1
Nasu, M; Tamura, A; Watanabe, T	1
Fujimura, A; Sugimoto, K	1
Bang, LM; Goa, KL	1
Gupta, S	1
Antonini-Canterin, F; Cervesato, E; Granata, G; Nicolosi, GL; Pavan, D; Piazza, R; Popescu, BA; Zuppiroli, A	1
Adamczyk, MA; Blasetto, JW; Bryzinski, BS; Cain, VA; Jones, PH; McKenney, JM	1
Granger, DN; Lefer, DJ; Tailor, A	1
Böhm, M; Herrmann, W; Laufs, U; Nickenig, G; Wassmann, S	1
Blomqvist, HM; Olsson, AG	1
Criqui, MH; Dimsdale, JE; Golomb, BA; White, H	1
Blasetto, J; Caplan, R; Dane, A; Hutchison, H; Strutt, K	1
Kröger, K; Wittlinger, T	1
Edwards, JE; Moore, RA	1
Backer, C; Crawford, SE; Mavroudis, C; Pahl, E; Rodgers, S; Seipelt, IM; Seipelt, RG	1
Tellier, P	1
Aeschlimann, SE; Bellehumeur, JL; Korcarz, CE; Mays, ME; Merwood, MA; Sosman, JM; Stein, JH; Underbakke, GL	1
Barter, PJ; Bonnet, J; Cheung, RC; Kallend, D; Morrell, JM; Raza, A; Schuster, H; Stender, S; Watkins, C	1
Inoue, Y; Moritan, T; Nagai, R; Ohtomo, K; Yokoyama, I	1
Egashira, K; Hirouchi, Y; Inoue, S; Kitajima, S; Kitamoto, S; Kohjimoto, Y; Nakano, K; Usui, M	1
Traut, V	1
Chasman, DI; Cook, NR; Posada, D; Ridker, PM; Stanton, VP; Subrahmanyan, L	1
Shiio, Y; Takagi, A	1
Ford, I; Lowe, GD; McMahon, AD; O'Reilly, DS; Packard, CJ; Rumley, A	1
Nissen, S	1
Benesic, A; Klinker, H; Kluge, F; Langmann, P; Weissbrich, B; Winzer, R; Zilly, M	1
Levenson, D	1
Brouwers, AH; de Graaf, L; Diemont, WL	1
Wehrly, TE; Yu, J	1
Cobbe, SM; Craven, T; Curhan, GC; Furberg, C; Isles, C; Pfeffer, MA; Sacks, FM; Shepherd, J; Simes, J; Tonelli, M; Tonkin, A; West, M	1
Chang, NC; Chou, TF; Lee, TM; Lin, MS; Tsai, CH	1
Khush, KK; Waters, D	1
Egido, J; Tuñón, J	1
Baggio, G; Bond, MG; Crepaldi, G; Gallus, G; Magni, A; Mancia, G; Rubba, P; Sampieri, L; Sperti, G; Veglia, F; Ventura, A; Zanchetti, A	1
März, W	1
Kotchen, TA	1
Blasetto, JW; Caplan, RJ; Ferdinand, KC; Gold, A; Hunninghake, DB; Jones, PH; Stein, EA	1
Cobbe, SM; Ford, I; Isles, CG; Lorimer, AR; MacFarlane, PW; McKillop, JH; Packard, CJ; Shepherd, J	2
Macfarlane, PW; Norrie, J	1
Endo, K; Ito, Y; Koide, N; Miyashita, Y; Otsuka, M; Oyama, T; Ozaki, H; Saiki, A; Shirai, K	1
Inami, S; Mizuno, K; Okamatsu, K; Sakai, S; Sano, J; Takagi, G; Takano, M	1
Fitchett, DH; Goodman, S; Langer, A; Leiter, LA; Tardif, JC	1
Hirsch, M; Jones, P; O'Donnell, JC	1
Kumagai, K; Matsunaga, A; Noda, K; Saku, K; Zhang, B	1
Koizumi, J; Mabuchi, H; Miyamoto, S; Origasa, H; Shimizu, M	1
Marian, AJ	1
Cheung, RC; Kallend, D; Morrell, JM; Schuster, H; Watkins, C	1
Almeida, EA; Carneiro, A; Jorge, M; Jorge, PA; Ozaki, MR	1
Battisti, WP; Brady, WE; Denke, MA; McBride, PE; Palmisano, J; Pearson, TA	1
Braunwald, E; Cannon, CP; Morrow, DA; Ridker, PM; Rifai, N; Rose, LM	1
Berna, C; Calmy, A; Junod, AF; Peytremann-Bridevaux, I	1
García-Iglesias, MF; Laguna, F; Lahoz, C; Mostaza, JM; Peña, R; Pintó, X; Taboada, M	2
Freedman, DB; Housley, D	1
Barter, P; Kallend, D; Schuster, H; Stender, S; Watkins, C	1
Kastelein, JJ; van Leuven, SI	1
Albert, MA; Glynn, RJ; Ridker, PM; Wolfert, RL	1
Hirose, T; Kawamori, R; Ohmura, C; Tanaka, Y; Watada, H	1
Goto, R; Higashi, K; Ishii, N; Itai, K; Kobori, S; Takahashi, T	1
Gordon, BR; Langman, CB; Levine, DM; Parker, TS; Rosenson, RS; Tangney, CC	1
Duthoit, C; Louboutin, A; Méry, L; Pauwels, C; Somogyi, A; Veyssier-Belot, C; Zuech, P	1
Baldassarre, S; Carpentier, YA; Deckelbaum, RJ; Ducobu, J; Dupont, IE; Scruel, O	1
Phillips, PS	1
Bots, AF; Kastelein, JJ	1
Badimon, L; Casani, L; Sanchez-Gomez, S; Vilahur, G	1
Ahumada, M; Arcas, R; Arribas, JM; Gomez-Plana, J; Marín, F; Martínez, P; Oliver, C; Pascual, DA; Tornel, PL; Valdes, M	1
Davis, SR; Goldstat, R; Malan, E; Peverill, RE; Smolich, JJ	1
Graselli, U; Joukhadar, C; Kostner, K; Lackner, E; Thallinger, C; Urbauer, E; Wolzt, M	1
Heemann, U; Kohnle, M; Kribben, A; Philipp, T; Pietruck, F; Witzke, O	1
Broncel, M; Chojnowska-Jezierska, J; Franiak, I; Koter-Michalak, M	1
Fukazawa, M; Ishikawa, M; Kubota, T; Moroi, M; Namiki, A; Sugi, K; Yajima, S	1
Carr, A; Cooper, DA; Feneley, MP; Kent-Hughes, J; Kovacic, JC; Mallon, PW; Miller, J; Norris, R; Samaras, K	1
Hayashi, J; Maeda, S; Ohnishi, H; Okada, K; Sawayama, Y	1
Filella, X; Franquesa, J; Marcos, JM; Molina, R; Morales, C; Salinas, R; Trapé, J	1
Kimura, M; Okamura, A; Takahashi, M; Takano, T; Yamakawa, T	1
Plans-Rubió, P	1
Allemann, C; Babiychuk, EB; Draeger, A; Hoppeler, H; Mohaupt, M; Monastyrskaya, K; Savolainen, H	1
Adams, V; Erbs, S; Goettsch, W; Hambrecht, R; Holtz, J; Krekler, M; Kuss, O; Lenk, K; Mohr, FW; Morawietz, H; Schubert, A; Schuler, G	1
Fiŝer, I; Kvas, E; Marschang, P; Patsch, JR; Ritsch, A; Sandhofer, A	1
Burioka, N; Ieiri, I; Miyata, M; Otsubo, K; Shigemasa, C; Shimizu, E; Takane, H	1
Davidson, MH; Robinson, JG	1
Carod-Artal, FJ	1
Knopp, RH; Paramsothy, P	1
Kawano, H; Yano, K	1
Ogawa, H; Sakamoto, K; Sakamoto, T	1
Boncoraglio, G; Ciusani, E; Croci, D; de Curtis, M; Frigerio, S; Gelati, M; Parati, E; Salmaggi, A	1
Calabresi, L; Sirtori, CR	1
Arakawa, K; Goto, Y; Itakura, H; Kitabatake, A; Mizuno, K; Muranaka, M; Nakamura, H; Nakaya, N; Nishimoto, S; Ohashi, Y; Toyota, T; Yamamoto, A	1
Kadonosono, K; Okamura, A; Takano, T; Utsunomiya, H; Yamakawa, T	1
Pitchumoni, CS; Tsigrelis, C	1
Boccara, F; Boutouyrie, P; Bozec, E; Cohen, A; Durant, S; Girard, PM; Lacombe, K; Laloux, B; Laurent, S; Simon, T	1
Nango, E; Saio, T; Yuasa, H	1
Moriguchi, H; Sato, C; Uemura, T	1
Albers, JJ; Galasko, D; Hazzard, WR; Lee, M; Lee, VM; Leverenz, JB; Li, G; Montine, TJ; Peskind, ER; Petrie, EC; Riekse, RG; Schellenberg, GD; Seubert, P; Vavrek, D; Vuletic, S	1
Ghribi, O	1
Arakawa, E; Hasegawa, K; Ina, Y; Matsubara, M; Takada, C; Takayama, M; Yao, K	1
Bedane, C; Bonnetblanc, JM; Boulinguez, S; Le Brun, V; Roux, C; Sparsa, A	1
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Hunninghake, D; Jones, P; Kafonek, S; Laurora, I	1
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Maranhão, RC; Santos, RD	1
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Lindbloom, EJ	1
Gaziano, JM; Lapsley, D; Strauss, WE	1
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Elliott, J; Ellis, C; McHaffie, D; Wilkins, G	1
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Nicholson, CR	1
Hartleb, M; Januszewski, K; Rymarczyk, G	1
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Fonarow, G; Hage, A; Hamilton, MA; Kawata, N; Kobashigawa, JA; Laks, H; Marelli, D; Moriguchi, JD	1
Agrawal, R; Arntz, HR; Fischer, F; Linderer, T; Schnitzer, L; Schultheiss, HP; Stern, R; Wunderlich, W	1
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Asanuma, H; Hori, M; Kitakaze, M; Komamura, K; Kuzuya, T; Minamino, T; Sato, H; Takeda, H; Ueda, Y	1
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Cicco, G; Pirrelli, A; Stingi, GD; Tarallo, MS; Vicenti, P	1
Bakker-Arkema, RG; Black, DM; Nawrocki, JW	1
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Dietschy, JM; Haley, RW	1
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Muntinga, JH; Reitsma, WD; Smit, AJ; Ubels, FL; van Doormaal, JJ	1
Gabbert, HE; Gerards, H; Heuer, T; Pauw, M; Reis, HE	1
Bettencourt, J; Davis, BR; Ford, CE; Furberg, CD; Geraci, TS; Kimmel, B; Kingry, C; Lusk, C; Nwachuku, C; Parks, H; Piller, LB; Pressel, SL; Simpson, LM; Wright, JT	1
Ma, L; Xu, L; Yin, S	1
Baggio, G; Bond, MG; Collatina, S; Crepaldi, G; Gallus, GV; Mancia, G; Rubba, P; Sampieri, L; Serrotti, E; Veglia, F; Ventura, A; Zanchetti, A	1
Dorner, GT; Joukhadar, C; Klein, N; Prinz, M; Schmetterer, L; Schrolnberger, C; Vukovich, T; Wolzt, M	1
Agrusta, M; Amodio, M; Corigliano, G; De Simone, G; Gaeta, I; Gentile, S; Guarino, G; Magliano, P; Oliviero, B; Salvatore, T; Sasso, CF; Torella, R; Turco, S	1
Dzien, A; Dzien-Bischinger, C; Hoppichler, F; Lechleitner, M	1
Barzilay, JI; Basile, JN; Ciocon, JO; Davis, BR; Goff, DC; Jones, CL; Randall, OS; Sweeney, ME	1
Bachmann, GA; Callister, TQ; Davidson, M; Kafonek, S; Laskey, R; Pittman, D; Raggi, P; Scott, R; Welty, FK	1
Goldman, L; Kuntz, KM; Orav, EJ; Sacks, FM; Tsevat, J; Weinstein, MC	1
Wierzbicki, AS	1
Aleixandre Porcar, L; Debón Belda, M; Martínez-Lahuerta, JJ; Murciano Revert, J	1
Fujita, H; Fujita, T; Fukumoto, S; Nakano, T; Takeuchi, Y; Watanabe, S	1
Furutani, N; Tada, N	1
Homma, Y	1
Ouchi, Y	1
Hague, W; Hunt, D; Lane, G; Mann, S; Owensby, D; Simes, J; Tonkin, A; Young, P	1
Ijzermans, JN; Vaessen, LM; van Gelder, T; van Miert, PP; Weimar, W	1
Ausiello, JC; Chaisson, CE; Stafford, RS; Wang, TJ	1
Waters, DD	1
Iizuka, A; Itakura, H; Komatsu, Y; Kondo, K; Kubo, M; Matsumiya, T; Matsumoto, A; Takeda, H; Yoshie, F	1
Orsi, A; Sherman, O; Woldeselassie, Z	1
Curiel, MD; De la Piedra, C; Lahoz, C; Mostaza, JM; Peña, R	1
Blann, AD; Buggins, P; Gurney, D; Hughes, E; Lip, GY; Silverman, SH	1
Mori, M; Nagai, T; Nakajima, K; Tomizawa, T	1
Galli, C; Pazzucconi, F; Risé, P; Sirtori, CR	1
Houghton, JL	1
Golomb, BA; Jaworski, B	1
Höyhtyä, M; Janatuinen, T; Kalela, A; Knuuti, J; Koivu, TA; Laaksonen, R; Lehtimäki, T; Nikkari, ST; Pöllänen, P; Saikku, P; Vesalainen, R	1
Arnesen, H; Eikvar, L; Eritsland, J; Seljeflot, I; Solheim, S	1
Baldwin, C; Gazzard, BG; Lloyd, M; Mandalia, S; Moyle, GJ; Reynolds, B	1
Bower, EA; Gibellato, MG; Moore, JL; Selby, K	1
Alton, KB; Burrier, RE; Davis, HR; Pula, KK; Watkins, RW	1
Janatuinen, T; Knuuti, J; Laaksonen, R; Lehtimäki, T; Nuutila, P; Raitakari, O; Vesalainen, R	1
Agro, A; Braeken, A; Hanna, K; McPherson, R	1
Brazg, R; Dujovne, CA; Insull, W; Isaacsohn, J; Kwiterovich, P; Patrick, MA; Ripa, S; Shan, M; Shugrue-Crowley, E; Stein, E; Tota, R	1
Igel, M; Sudhop, T; von Bergmann, K	1
Alfón, J; Badimon, L; Berrozpe, M; Martínez-González, J	1
Cesar, LA; Coelho, OR; Mansur, AP; Maranhão, M; Ramires, JA; Sposito, AC	1
Gathe, JC; Lahart, C; Stone, VE	1
Adelman, A	1
Déchêne, F; Dodin, S; Forest, JC; Lemay, A; Turcot, L	1
Aeschlimann, SE; Bodemer, A; Carlsson, CM; Carnes, M; McBride, PE; Papcke-Benson, K; Stein, JH	1
Bloomfield, P; Boon, NA; Fox, KA; Ludlam, CA; Newby, DE; Webb, DJ; Witherow, FN; Wright, RA	1
Bayerle-Eder, M; Bischof, MG; Fuchsjäger-Mayrl, G; Polska, E; Roden, M; Schmetterer, L; Sieder, A; Stulnig, T; Waldhäusl, W; Wolzt, M	1
Ishikawa, T; Ito, H; Nakamura, H; Ohashi, Y; Orimo, H; Ouchi, Y; Saito, Y	1
Chau, J; Cheung, BM; Kumana, CR; Lau, CP; Lauder, IJ; McGhee, SM	1
Dubská, L; Dvoráková, J; Hyánek, J; Táborský, L	1
Graham, MR; Kennedy, JA; Lindsey, CC	1
Bilgin, O; Koc, T; Ozsener, S; Oztekin, K; Sendag, F; Terek, MC	1
Hayashi, M; Inoue, T; Morooka, S; Takayanagi, K	1
Hayashi, J; Kashiwagi, S; Kinukawa, N; Koyanagi, S; Maeda, N; Sawayama, Y; Shimizu, C; Tatsukawa, M	1
Hsu, SX; Ma, LP; Nie, DN; Nunes, JV; Xu, LZ; Yin, SM	1
Fahmy, M; Mahla, G; Mizan, J; Paoletti, R; Southworth, H	1
Feng, J; Li, Z; Ma, L; Nie, D; Xie, S; Xu, L; Yang, Y; Yin, S	1
Barbaki, P; Dagre, AG; Lekakis, JP; Papaioannou, TG; Papamichael, CM; Stamatelopoulos, KS; Stamatelopoulos, SF	1
Basso, F; Humphries, SE; Lowe, GD; McMahon, AD; Rumley, A	1
Campistol, JM; Casals, E; Cofan, F; Cofan, M; Laguna, JC; Oppenheimer, F; Ros, E; Zambon, D	1
Goto, Y; Hata, Y; Itakura, H; Mabuchi, H; Nakaya, N; Ogawa, N; Saito, Y; Sasaki, J; Teramoto, T; Tushima, M; Yamada, N	1
Asayama, J; Azuma, A; Nakagawa, M; Nakata, T; Sasaki, S; Sawada, S; Takeda, K	1
Aoyagi, S; Fujii, T; Hiromoto, M; Itoh, S; Matsuzaki, M; Tanaka, M; Toma, Y; Tomochika, Y; Umemoto, S	1
Braunwald, E; Byington, RP; Cobbe, SM; Davis, BR; Friedman, CP; Keech, A; Pfeffer, MA; Sacks, FM; Tonkin, A	1
Itakura, H	1
Baccante, G; Cuccurullo, F; Di Febbo, C; Di Nisio, M; Porreca, E	1
Auteri, A; Bova, G; Bruni, F; Cercignani, M; Console, E; Palazzuoli, A; Pasqui, AL; Puccetti, L	1
Hinman, J; Scanu, AM	1
Ambrosio, G; Chiariello, M; Lepore, S; Napoli, C	1
Fujinami, T; Ichikawa, T; Iwata, S; Sakuma, N	1
Giannini, SD	1
Braunsteiner, H; Hoppichler, F; Konwalinka, G; Lechleitner, M; Patsch, JR	1
Clifton, P; Janus, ED; Nestel, PJ; Parfitt, A; Simons, J; Simons, LA	1
Cohen, L; Crommelin, D; Geelhoed-Mieras, T; Griffioen, M; Joles, J; Koomans, H; Krajnc-Franken, M; Van Bloois, L; Van Tol, A; Willekes-Koolschijn, N	1
Alessandri, C; Peverini, F	2
Altomare, S; Citella, C; Colombo, L; Craveri, A; Giavardi, L; Lanfredini, M; Pedrazzini, L; Picollo, S; Vignati, A	1
Hoppichler, F; Lechleitner, M; Patsch, JR	1
Cluysenaer, OJ; Erkelens, DW; Geerdink, RA; Smit, JW; Stolk, MF; van Berge Henegouwen, GP; van Erpecum, KJ	1
Cantral, KA; Jungnickel, PW; Maloley, PA	1
Jacob, BG; Möhrle, W; Richter, WO; Schwandt, P	1
Hisatomi, A; Inoue, K; Kunisaki, M; Mimura, K; Nawata, H; Sako, Y; Tajiri, Y; Umeda, F; Watanabe, J; Yamauchi, T	1
Behrens-Baumann, W; Thiery, J	1
Aviram, M; Brook, GJ; Hoffman, R	1
Kostis, JB; Wilson, AC	1
Illingworth, DR	1
McTavish, D; Sorkin, EM	1
Ohmori, Y; Oka, T; Okamoto, M; Yoshimura, N	1
Armstrong, VW; Fieseler, HG; Schütz, E; Seidel, D; Thiery, J; Walli, AK; Wieland, E	1
Arca, M; Avellone, G; Avogaro, P; Baggio, G; Bittolo Bon, G; Bompiani, GD; Capurso, A; Cattin, L; Crepaldi, G; D'Alŏ, G	1
Arbeeny, CM; Bergquist, KE	1
Collins, P; Johnson, A; Owens, D; Robinson, K; Tighe, O; Tomkin, GH	1
Dammann, HG; Ditschuneit, H; Ditschuneit, HH; Dreyer, M	1
Berkson, DM; Colfer, HT; Cressman, MD; Farmer, JA; Farnham, DJ; Jones, PH; McKenney, JM; Proctor, JD; Wolfson, PM; Wright, JT	1
Ditschuneit, H; Ditschuneit, HH; Kuhn, K	1
Barrow, SE; Benjamin, N; Brassfield, T; Ritter, JM; Stratton, PD	1
Dobs, AS; Sarma, PS; Wilder, L	1
Raasch, RH	1
Blevins, RD; Kobylak, L; Maciejko, JJ; Orringer, C; Rosman, H; Rubenfire, M	1
Grundy, SM; Krauss, RM; Vega, GL	1
Ishida, F; Kakubari, K; Kamei, T; Kitani, K; Sato, A; Taguchi, K; Watanabe, K	1
Bard, JM; Douste-Blazy, P; Fruchart, JC; Parra, HJ	1
Aronson, JK; Ng, LL	1
Maher, VM; Thompson, GR	1
Brescia, D; DeVault, AR; Ivashkiv, E; Pan, HY; Swites, BJ; Whigan, D; Willard, DA	1
Brown, WV; Dobs, AS; Goldberg, AC; Hunninghake, DB; Insull, W; Knopp, RH; Margolis, S; Mellies, MJ; Schaefer, EJ; Schonfeld, G	1
Bruschi, R; Citella, C; Colombo, L; Craveri, A; Lanfredini, M	1
Bimmermann, A; Schleicher, J; Schwartzkopff, W	1
Behrens-Baumann, W; Fieseler, HG; Seidel, D; Thiery, J	1
Hockwin, O; Schmidt, J; Schmitt, C	1
Goldberg, AC; Hunninghake, DB; Insull, W; Kostis, JB; Kuo, PT; Mellies, MJ; Pan, HY; Schrott, HG	1
Baba, S; Iwai, M; Iwatani, I; Kazumi, T; Matsuba, K; Matsushita, M; Uenoyama, R; Yoshino, G	1
Blevins, RD; Levinson, SS; Maciejko, JJ; Rubinfire, M; Smith, MP	1
Baba, S; Inui, A; Iwai, M; Iwatani, I; Kasama, T; Kazumi, T; Otsuki, M; Uenoyama, R; Yokono, K; Yoshino, G	1
Baba, S; Inui, A; Iwai, M; Iwatani, I; Kasama, T; Kazumi, T; Otsuki, M; Yoshino, G	1
Goto, Y; Hata, Y; Homma, Y; Nakaya, N; Shigematsu, H; Tamachi, H	1
Brown, WV; Karmally, W; Smith, DA	1
Goto, Y; Hata, Y; Hayashi, H; Homma, Y; Ito, H; Naito, C; Nakaya, N; Saito, Y; Takeuchi, I; Yamamoto, M	1

Reviews

72 review(s) available for pravastatin and Hypercholesterolemia

Article	Year
Expanded table: statins. The Medical letter on drugs and therapeutics, 2019, Sep-23, Volume: 61, Issue:1581 Topics: Anticholesteremic Agents; Delayed-Action Preparations; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Statistics as Topic	2019
The effect of statins on semen parameters in patients with hypercholesterolemia: A systematic review. Andrology, 2021, Volume: 9, Issue:5 Topics: Adult; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies; Randomized Controlled Trials as Topic; Semen; Simvastatin; Sperm Motility	2021
Pravastatin: an evidence-based statin? Expert opinion on drug metabolism & toxicology, 2008, Volume: 4, Issue:6 Topics: Atherosclerosis; Cardiovascular Diseases; Evidence-Based Medicine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Practice Guidelines as Topic; Pravastatin; Treatment Outcome	2008
[Pleiotropic effects of statins]. Revista medica de Chile, 2008, Volume: 136, Issue:6 Topics: Anticholesteremic Agents; Antioxidants; Atherosclerosis; Atorvastatin; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Oxidative Stress; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides	2008
Pharmacogenomic importance of pravastatin. Pharmacogenomics, 2008, Volume: 9, Issue:9 Topics: Animals; Anticholesteremic Agents; Genetic Variation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pharmacogenetics; Pravastatin	2008
The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy. The pharmacogenomics journal, 2010, Volume: 10, Issue:1 Topics: Anticholesteremic Agents; Asian People; Atorvastatin; Fluorobenzenes; Gene Frequency; Haplotypes; HeLa Cells; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Pharmacogenetics; Polymorphism, Single Nucleotide; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2010
Office-based global cardiometabolic risk assessment: a simple tool incorporating nontraditional markers. Critical pathways in cardiology, 2010, Volume: 9, Issue:3 Topics: Atorvastatin; Biomarkers; Cardiovascular Diseases; Clinical Trials as Topic; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Hypertension; Male; Obesity; Office Visits; Practice Patterns, Physicians'; Pravastatin; Pyrroles; Risk Assessment; Smoking; United States	2010
Pitavastatin - results from phase III & IV. Atherosclerosis. Supplements, 2010, Volume: 11, Issue:3 Topics: Atorvastatin; Clinical Trials, Phase III as Topic; Clinical Trials, Phase IV as Topic; Dyslipidemias; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Pyrroles; Quinolines; Simvastatin	2010
[Indications for statin therapy in patients with acute coronary syndrome of ischemic origin]. Giornale italiano di cardiologia (2006), 2010, Volume: 11, Issue:10 Suppl 1 Topics: Acute Coronary Syndrome; Anticholesteremic Agents; Atorvastatin; Cholesterol; Electrocardiography; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Myocardial Infarction; Practice Guidelines as Topic; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Risk Factors; Secondary Prevention	2010
The complex interplay between cholesterol and prostate malignancy. The Urologic clinics of North America, 2011, Volume: 38, Issue:3 Topics: Androgens; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Pravastatin; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors	2011
Targeting HDL-cholesterol to reduce residual cardiovascular risk. Current opinion in lipidology, 2012, Volume: 23, Issue:2 Topics: Atorvastatin; Cardiovascular Diseases; Cholesterol, HDL; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Pyrimidines; Pyrroles; Risk Factors; Rosuvastatin Calcium; Sulfonamides	2012
Clinical inquiries. What is the target for low-density lipoprotein cholesterol in patients with heart disease? The Journal of family practice, 2002, Volume: 51, Issue:10 Topics: Cholesterol, LDL; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Simvastatin	2002
Benefits and menaces related to the use of statins in patients after renal transplantation. Annals of transplantation, 2002, Volume: 7, Issue:2 Topics: Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Transplantation; Lovastatin; Postoperative Complications; Pravastatin; Pyrroles; Simvastatin	2002
[Primary and secondary prevention of coronary disease by statins]. Annales de cardiologie et d'angeiologie, 1999, Volume: 48, Issue:2 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Angiography; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pravastatin; Primary Prevention; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Simvastatin; Survival Analysis; Survival Rate; Treatment Outcome	1999
Non-high-density lipoprotein cholesterol: a target of lipid-lowering in dialysis patients. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:3 Suppl 1 Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Pyrroles; Renal Dialysis; Simvastatin	2003
Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials. Archives of internal medicine, 2003, Mar-24, Volume: 163, Issue:6 Topics: Anticholesteremic Agents; Atorvastatin; Cholestyramine Resin; Clofibrate; Colestipol; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Myocardial Infarction; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Regression Analysis; Risk Assessment; Risk Factors; Simvastatin; Stroke; Treatment Failure; Treatment Outcome	2003
Efficacy of rosuvastatin compared with other statins at selected starting doses in hypercholesterolemic patients and in special population groups. The American journal of cardiology, 2003, Mar-06, Volume: 91, Issue:5A Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Drug Administration Schedule; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Least-Squares Analysis; Male; Middle Aged; Multicenter Studies as Topic; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2003
Guidelines for lowering lipids to reduce coronary artery disease risk: a comparison of rosuvastatin with atorvastatin, pravastatin, and simvastatin for achieving lipid-lowering goals. The American journal of cardiology, 2003, Mar-06, Volume: 91, Issue:5A Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Drug Administration Schedule; Europe; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Multicenter Studies as Topic; Practice Guidelines as Topic; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Risk; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2003
Lipid and apolipoprotein ratios: association with coronary artery disease and effects of rosuvastatin compared with atorvastatin, pravastatin, and simvastatin. The American journal of cardiology, 2003, Mar-06, Volume: 91, Issue:5A Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Europe; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Least-Squares Analysis; Lipids; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2003
Acute pancreatitis due to pravastatin therapy. JOP : Journal of the pancreas, 2003, Volume: 4, Issue:3 Topics: Acute Disease; Anticholesteremic Agents; Humans; Hypercholesterolemia; Male; Middle Aged; Pancreatitis; Pravastatin	2003
Hypercholesterolemia. The evidence supports use of statins. Geriatrics, 2003, Volume: 58, Issue:8 Topics: Aged; Cholesterol, HDL; Coronary Artery Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Metabolic Syndrome; Pravastatin; Simvastatin	2003
Pravastatin: a review of its use in elderly patients. Drugs & aging, 2003, Volume: 20, Issue:14 Topics: Adult; Aged; Clinical Trials as Topic; Drug Interactions; Female; Geriatrics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Male; Middle Aged; Pravastatin; Tissue Distribution	2003
Conceptual foundations of the UCSD Statin Study: a randomized controlled trial assessing the impact of statins on cognition, behavior, and biochemistry. Archives of internal medicine, 2004, Jan-26, Volume: 164, Issue:2 Topics: Aggression; Angiotensin-Converting Enzyme Inhibitors; Cholesterol; Cognition; Humans; Hypercholesterolemia; Pravastatin; Randomized Controlled Trials as Topic; Serotonin; Simvastatin; United States	2004
More Western hypercholesterolemic patients achieve Japan Atherosclerosis Society LDL-C goals with rosuvastatin therapy than with atorvastatin, pravastatin, or simvastatin therapy. Circulation journal : official journal of the Japanese Circulation Society, 2004, Volume: 68, Issue:2 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Drug Evaluation; Europe; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Japan; Male; Middle Aged; Multicenter Studies as Topic; Pravastatin; Pyrimidines; Pyrroles; Racial Groups; Randomized Controlled Trials as Topic; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome; United States	2004
[Role of lipid lowering therapy in patients with peripheral arterial occlusive disease]. Herz, 2004, Volume: 29, Issue:1 Topics: Anticholesteremic Agents; Arterial Occlusive Diseases; Atorvastatin; Disease Progression; Exercise Test; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Jejunoileal Bypass; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome	2004
Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials. BMC family practice, 2003, Dec-01, Volume: 4 Topics: Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Pravastatin; Pyridines; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Triglycerides	2003
[Ezetimibe: from pharmacology to clinical trials]. Annales d'endocrinologie, 2003, Volume: 64, Issue:6 Topics: Animals; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Depression, Chemical; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Hypercholesterolemia; Intestinal Absorption; Liver; Lovastatin; Pravastatin; Pyrroles; Safety; Simvastatin; Treatment Outcome	2003
Is decreased libido associated with the use of HMG-CoA-reductase inhibitors? British journal of clinical pharmacology, 2004, Volume: 58, Issue:3 Topics: Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Libido; Male; Middle Aged; Pravastatin	2004
Effect of pravastatin on cardiovascular events in people with chronic kidney disease. Circulation, 2004, Sep-21, Volume: 110, Issue:12 Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Chronic Disease; Comorbidity; Coronary Disease; Creatinine; Databases, Factual; Double-Blind Method; Drug Evaluation; Female; Glomerular Filtration Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Diseases; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Pravastatin; Randomized Controlled Trials as Topic; Risk	2004
Are Canadian guidelines for cholesterol lowering in high-risk patients optimal? The Canadian journal of cardiology, 2005, Volume: 21, Issue:1 Topics: Atorvastatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Maximum Tolerated Dose; Practice Guidelines as Topic; Pravastatin; Prognosis; Pyrroles; Quebec; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome	2005
Atorvastatin. Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:7 Topics: Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Cardiovascular Diseases; Carotid Arteries; Cholesterol, LDL; Coronary Artery Disease; Drug Interactions; Endothelium, Vascular; Forecasting; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Leukocytes; Pravastatin; Proportional Hazards Models; Pyrroles; Randomized Controlled Trials as Topic	2005
Combination therapy with ezetimibe and simvastatin to achieve aggressive LDL reduction. Expert review of cardiovascular therapy, 2006, Volume: 4, Issue:4 Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; C-Reactive Protein; Cardiovascular Diseases; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Lipoproteins, LDL; Phytosterols; Pravastatin; Pyrroles; Simvastatin	2006
Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials. Journal of the American College of Cardiology, 2007, Jul-31, Volume: 50, Issue:5 Topics: Chemical and Drug Induced Liver Injury; Cholesterol, LDL; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Liver Diseases; Lovastatin; Neoplasms; Pravastatin; Rhabdomyolysis; Simvastatin	2007
Pravastatin experience in elderly and non-elderly patients. Atherosclerosis, 1993, Volume: 101, Issue:1 Topics: Adult; Age Factors; Aged; Cholesterol; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Triglycerides	1993
[Rhabdomyolysis caused by pravastatin and type 1 macrocreatine kinase]. Annales de cardiologie et d'angeiologie, 1993, Volume: 42, Issue:5 Topics: Creatine Kinase; Female; Humans; Hypercholesterolemia; Middle Aged; Pravastatin; Rhabdomyolysis	1993
Benefits and risks of HMG-CoA reductase inhibitors in the prevention of coronary heart disease: a reappraisal. Drug safety, 1996, Volume: 14, Issue:1 Topics: Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Simvastatin	1996
Hyperlipidaemia and cardiovascular disease. Current opinion in lipidology, 1996, Volume: 7, Issue:3 Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Pravastatin	1996
Therapy and clinical trials. Current opinion in lipidology, 1996, Volume: 7, Issue:3 Topics: Anticholesteremic Agents; Humans; Hypercholesterolemia; Myocardial Infarction; Pravastatin; Randomized Controlled Trials as Topic	1996
Pravastatin. A reappraisal of its pharmacological properties and clinical effectiveness in the management of coronary heart disease. Drugs, 1997, Volume: 53, Issue:2 Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Pravastatin	1997
Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences. Clinical pharmacokinetics, 1997, Volume: 32, Issue:5 Topics: Anticholesteremic Agents; Arteriosclerosis; Brain; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Food-Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Liver; Lovastatin; Pravastatin; Simvastatin	1997
Lipoproteins and cardiovascular reactivity. British journal of clinical pharmacology, 1997, Volume: 44, Issue:4 Topics: Animals; Anticholesteremic Agents; Cholesterol, LDL; Clinical Trials as Topic; Coronary Vessels; Humans; Hypercholesterolemia; Lipoproteins; Pravastatin; Vasoconstriction; Vasodilation	1997
The hypertensive patient with multiple risk factors: is treatment really so difficult? American journal of hypertension, 1997, Volume: 10, Issue:10 Pt 2 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticholesteremic Agents; Antihypertensive Agents; Arteriosclerosis; Clinical Trials as Topic; Coronary Disease; Female; Fosinopril; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Pravastatin; Risk Factors	1997
Review of recent clinical trials of lipid lowering in coronary artery disease. The American journal of cardiology, 1997, Oct-30, Volume: 80, Issue:8B Topics: Anticholesteremic Agents; Clinical Trials as Topic; Coronary Disease; Humans; Hypercholesterolemia; Pravastatin; Simvastatin	1997
[Endothelium, lipids and atherosclerosis]. Arquivos brasileiros de cardiologia, 1997, Volume: 68, Issue:2 Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Endocytosis; Endothelium, Vascular; Foam Cells; Humans; Hypercholesterolemia; Lipoproteins, LDL; Pravastatin; Probucol; Rabbits; Vitamin E	1997
Cholesterol lowering in the management of coronary artery disease: the clinical implications of recent trials. The American journal of medicine, 1998, Feb-23, Volume: 104, Issue:2A Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Humans; Hypercholesterolemia; Pravastatin; Randomized Controlled Trials as Topic	1998
Prevention. Who should take cholesterol-lowering drugs? Harvard health letter, 1998, Volume: 23, Issue:3 Topics: Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Estrogen Replacement Therapy; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Myocardial Ischemia; Pravastatin	1998
[Are there differences in various statins?]. Der Internist, 1998, Volume: 39, Issue:9 Topics: Anticholesteremic Agents; Cholesterol; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin; Treatment Outcome; Triglycerides	1998
[The impact HMG-CoA reductase inhibitors on the modification of the natural history of coronary artery disease]. Arquivos brasileiros de cardiologia, 1998, Volume: 71, Issue:2 Topics: Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Pravastatin	1998
[Statins (HMG-CoA reductase inhibitors), cholesterol and stroke]. Revista de neurologia, 1998, Volume: 27, Issue:159 Topics: Adult; Arteriosclerosis; Cerebrovascular Disorders; Cholesterol; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ischemic Attack, Transient; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Pravastatin; Risk Factors; Simvastatin; Triglycerides	1998
Does cholesterol lowering prevent stroke? Journal of clinical pharmacy and therapeutics, 1998, Volume: 23, Issue:5 Topics: Anticholesteremic Agents; Arteriosclerosis; Cerebrovascular Disorders; Diagnostic Imaging; Humans; Hypercholesterolemia; Meta-Analysis as Topic; Multicenter Studies as Topic; Pravastatin; Risk Factors	1998
[The new debate on cholesterol: is the lowest level the best?]. Lakartidningen, 1999, Feb-10, Volume: 96, Issue:6 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Female; Guidelines as Topic; Humans; Hypercholesterolemia; Male; Pravastatin; Randomized Controlled Trials as Topic; Risk Factors; Scotland; Simvastatin; Sweden	1999
Statins and cerebrovascular disease: plaque attack to prevent brain attack. Vascular medicine (London, England), 1999, Volume: 4, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Blood Vessels; Clinical Trials as Topic; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Pravastatin; Stroke	1999
Hemorheology and tissue oxygenation in hypertensives with lipoidoproteinosis and peripheral occlusive arterial disease (POAD) treated with sulodexide and pravastatine and evaluated with laser assisted optical rotational red cell analyzer (LORCA) and trans Minerva cardioangiologica, 1999, Volume: 47, Issue:10 Topics: Adult; Aged; Blood Gas Monitoring, Transcutaneous; Female; Glycosaminoglycans; Hemorheology; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Laser-Doppler Flowmetry; Lasers; Lipoid Proteinosis of Urbach and Wiethe; Male; Middle Aged; Peripheral Vascular Diseases; Pravastatin	1999
Safety profile of atorvastatin-treated patients with low LDL-cholesterol levels. Atherosclerosis, 2000, Volume: 149, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Severity of Illness Index; Simvastatin; Treatment Outcome	2000
[Additional effects of statins independent of the cholesterol-lowering as yet not shown to be clinically relevant]. Nederlands tijdschrift voor geneeskunde, 2000, Feb-12, Volume: 144, Issue:7 Topics: Anticholesteremic Agents; Arteriosclerosis; Clinical Trials as Topic; Confounding Factors, Epidemiologic; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Simvastatin	2000
Bridging the treatment gap. The American journal of cardiology, 2000, Jun-22, Volume: 85, Issue:12A Topics: Adult; Anticholesteremic Agents; Cardiovascular Diseases; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Risk Factors; Self Medication; Simvastatin; United States	2000
Statin therapy: where are we? Where do we go next? The American journal of cardiology, 2001, Mar-08, Volume: 87, Issue:5A Topics: Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Practice Guidelines as Topic; Pravastatin; Primary Prevention; Risk Factors	2001
[WOSCOPS [West of Scotland Coronary Prevention Study]]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 3 Topics: Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Scotland	2001
[LIPID study [Long-term Intervention with Pravastatin in Ischaemic Disease study]]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 3 Topics: Aged; Anticholesteremic Agents; Coronary Disease; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Risk; Time Factors; Treatment Outcome	2001
[PATE Study [Pravastatin anti-Atherosclerosis Trial in the Elderly Study]]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 3 Topics: Aged; Aged, 80 and over; Arteriosclerosis; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Female; Humans; Hypercholesterolemia; Japan; Male; Middle Aged; Pravastatin; Prospective Studies; Risk	2001
What do the statin trials tell us? The American journal of managed care, 2001, Volume: 7, Issue:5 Suppl Topics: Anticholesteremic Agents; Clinical Trials as Topic; Coronary Disease; Female; Humans; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Male; Outcome Assessment, Health Care; Pravastatin; Stroke; United States	2001
Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins). European journal of clinical pharmacology, 2001, Volume: 57, Issue:5 Topics: Atorvastatin; Drug Interactions; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Pyridines; Pyrroles; Simvastatin	2001
Resource management in prevention of coronary heart disease: optimising prescription of lipid-lowering drugs. Lancet (London, England), 2002, Jun-29, Volume: 359, Issue:9325 Topics: Aged; Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Middle Aged; Practice Guidelines as Topic; Pravastatin; Risk Factors	2002
[Evaluation of the therapeutic efficacy of pravastatin in monothereapy and in association with gemfibrozil in hypercholesterolemia associated with moderate hyperglyceridemia]. Cardiologia (Rome, Italy), 1992, Volume: 37, Issue:11 Topics: Aged; Drug Evaluation; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertriglyceridemia; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Pravastatin	1992
[Clinical evaluation of a selective inhibitor of cholesterol synthesis: pravastatin]. Minerva medica, 1992, Volume: 83, Issue:11 Topics: Adult; Animals; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Guinea Pigs; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Pravastatin; Rats; Risk Factors; Simvastatin; Time Factors	1992
[Pravastatin, a new cholesterol synthesis inhibitor for lowering increased serum cholesterol]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1992, Volume: 47, Issue:11 Topics: Cholesterol; Cholesterol, LDL; Humans; Hypercholesterolemia; Pravastatin; Risk Factors	1992
Pravastatin: a new drug for the treatment of hypercholesterolemia. Clinical pharmacy, 1992, Volume: 11, Issue:8 Topics: Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Interactions; Drug Therapy, Combination; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Pravastatin	1992
Clinical implications of new drugs for lowering plasma cholesterol concentrations. Drugs, 1991, Volume: 41, Issue:2 Topics: Anticholesteremic Agents; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Lovastatin; Naphthalenes; Pravastatin; Simvastatin	1991
Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs, 1991, Volume: 42, Issue:1 Topics: Animals; Anticholesteremic Agents; Humans; Hypercholesterolemia; Pravastatin	1991
[Hypercholesterolemia: therapeutic approach]. La Clinica terapeutica, 1991, Jun-30, Volume: 137, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Enzyme Inhibitors; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Naphthalenes; Pravastatin; Simvastatin	1991
Pravastatin sodium, a new HMG-CoA reductase inhibitor. DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:4 Topics: Animals; Anticholesteremic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin	1991
HMG CoA reductase inhibitors in the treatment of hypercholesterolaemias. The Quarterly journal of medicine, 1990, Volume: 74, Issue:274 Topics: Anticholesteremic Agents; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Naphthalenes; Pravastatin; Simvastatin	1990

Trials

328 trial(s) available for pravastatin and Hypercholesterolemia

Article	Year
Effect of Statin Treatment vs Usual Care on Primary Cardiovascular Prevention Among Older Adults: The ALLHAT-LLT Randomized Clinical Trial. JAMA internal medicine, 2017, 07-01, Volume: 177, Issue:7 Topics: Aged; Antihypertensive Agents; Cardiovascular Diseases; Cholesterol, LDL; Drug Monitoring; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Medication Therapy Management; Outcome and Process Assessment, Health Care; Pravastatin; Primary Prevention; United States	2017
Drug effect of atorvastatin on middle cerebral atherosclerotic stenosis and high resolution NMR diagnosis. Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:3(Special) Topics: Aged; Atherosclerosis; Atorvastatin; Constriction, Pathologic; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Magnetic Resonance Imaging; Male; Middle Aged; Middle Cerebral Artery; Pravastatin; Rosuvastatin Calcium; Simvastatin	2018
Intensive lipid-lowering therapy for slowing progression as well as inducing regression of atherosclerosis in Japanese patients: subanalysis of the JART study. International heart journal, 2013, Volume: 54, Issue:1 Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Carotid Intima-Media Thickness; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; Female; Fluorobenzenes; Humans; Hypercholesterolemia; Japan; Lipid Metabolism; Male; Middle Aged; Outcome Assessment, Health Care; Pharmacovigilance; Pravastatin; Preventive Health Services; Pyrimidines; Risk Assessment; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome	2013
Effects of pravastatin on serum adiponectin levels in female patients with type 2 diabetes mellitus. Atherosclerosis, 2013, Volume: 227, Issue:2 Topics: Adiponectin; Adult; Aged; Body Mass Index; Diabetes Complications; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Middle Aged; Pravastatin	2013
Importance of high-density lipoprotein cholesterol control during pravastatin treatment in hypercholesterolemic Japanese with type 2 diabetes mellitus: a post hoc analysis of MEGA study. Diabetes research and clinical practice, 2013, Volume: 100, Issue:2 Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin	2013
Combination pravastatin and valsartan treatment has additive beneficial effects to simultaneously improve both metabolic and cardiovascular phenotypes beyond that of monotherapy with either drug in patients with primary hypercholesterolemia. Diabetes, 2013, Volume: 62, Issue:10 Topics: Angiotensin II Type 1 Receptor Blockers; Body Mass Index; Brachial Artery; C-Reactive Protein; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Endothelium, Vascular; Female; Glycated Hemoglobin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin Resistance; Lipids; Male; Middle Aged; Phenotype; Pravastatin; Tetrazoles; Treatment Outcome; Valine; Valsartan	2013
Long-term follow-up of moderately hypercholesterolemic hypertensive patients following randomization to pravastatin vs usual care: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT). Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:8 Topics: Aged; Anticholesteremic Agents; Black People; Cohort Studies; Coronary Disease; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Patient Compliance; Pravastatin; Risk Factors; Treatment Outcome	2013
The relationship between low-density lipoprotein cholesterol levels and the incidence of cardiovascular disease in high-risk patients treated with pravastatin: main results of the APPROACH-J study. International heart journal, 2014, Volume: 55, Issue:1 Topics: Aged; Atherosclerosis; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Japan; Male; Middle Aged; Pravastatin; Prospective Studies	2014
Model selection criterion for causal parameters in structural mean models based on a quasi-likelihood. Biometrics, 2014, Volume: 70, Issue:3 Topics: Age Distribution; Anticholesteremic Agents; Biomarkers; Body Mass Index; Causality; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Japan; Likelihood Functions; Male; Medication Adherence; Outcome Assessment, Health Care; Pravastatin; Prevalence; Reproducibility of Results; Risk Assessment; Sensitivity and Specificity; Treatment Outcome	2014
Assessment of lipophilic vs. hydrophilic statin therapy in acute myocardial infarction – ALPS-AMI study. Circulation journal : official journal of the Japanese Circulation Society, 2015, Volume: 79, Issue:1 Topics: Aged; Atorvastatin; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Female; Glycated Hemoglobin; Heart Failure; Hospitalization; Humans; Hydrophobic and Hydrophilic Interactions; Hypercholesterolemia; Japan; Kaplan-Meier Estimate; Lipids; Male; Middle Aged; Mortality; Myocardial Infarction; Myocardial Revascularization; Patient Acceptance of Health Care; Pravastatin; Recurrence; Single-Blind Method; Solubility	2015
[IMPROVE-IT Study proves effectiveness of ezetimib. The Higgs particle of lipidologists]. MMW Fortschritte der Medizin, 2014, Dec-15, Volume: 156, Issue:21-22 Topics: Acute Coronary Syndrome; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Pravastatin; Pyrroles; Simvastatin	2014
Effects of pravastatin, phytosterols, and combination therapy on lipid profile in HIV-infected patients: an open-labelled, randomized cross-over study. BMC research notes, 2015, Jul-07, Volume: 8 Topics: Adult; Anticholesteremic Agents; Cholesterol, LDL; Cross-Over Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Hypercholesterolemia; Male; Middle Aged; Phytosterols; Pravastatin	2015
A Comparison of Statin Therapies in Hypercholesterolemia in Women: A Subgroup Analysis of the STELLAR Study. Journal of women's health (2002), 2016, Volume: 25, Issue:1 Topics: Adult; Aged; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Middle Aged; Pravastatin; Rosuvastatin Calcium; Simvastatin; Treatment Outcome; Triglycerides; United States	2016
Progression of kidney disease in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin versus usual care: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 52, Issue:3 Topics: Aged; Anticholesteremic Agents; Cholesterol; Disease Progression; Female; Glomerular Filtration Rate; Humans; Hypercholesterolemia; Hypertension; Incidence; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged; Pravastatin; Treatment Outcome	2008
Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients. Atherosclerosis, 2009, Volume: 204, Issue:2 Topics: Adiponectin; C-Reactive Protein; Double-Blind Method; Endothelium, Vascular; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin; Insulin Resistance; Leptin; Lipoproteins; Male; Middle Aged; Pravastatin; Simvastatin; Treatment Outcome; Vasodilation	2009
Rosuvastatin, pravastatin, and atorvastatin for the treatment of hypercholesterolaemia in HIV-infected patients receiving protease inhibitors. Current HIV research, 2008, Volume: 6, Issue:6 Topics: Adult; Anticholesteremic Agents; Atorvastatin; Cholesterol; Female; Fluorobenzenes; Follow-Up Studies; Heptanoic Acids; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome; Viral Load	2008
A randomized, multicentre, open-label, parallel-group trial to compare the efficacy and safety profile of daming capsule in patients with hypercholesterolemia. Phytotherapy research : PTR, 2009, Volume: 23, Issue:7 Topics: Adult; Alanine Transaminase; Anticholesteremic Agents; Blood Pressure; Body Mass Index; Capsules; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Drugs, Chinese Herbal; Female; Heart Rate; Humans; Hypercholesterolemia; Male; Medicine, Chinese Traditional; Pravastatin; Triglycerides	2009
Should high creatine kinase discourage the initiation or continuance of statins for the treatment of hypercholesterolemia? Metabolism: clinical and experimental, 2009, Volume: 58, Issue:2 Topics: Atorvastatin; Cholesterol, LDL; Creatine Kinase; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Rhabdomyolysis; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2009
Tolerability and effects on lipids of ezetimibe coadministered with pravastatin or simvastatin for twelve months: results from two open-label extension studies in hypercholesterolemic patients. Clinical therapeutics, 2008, Volume: 30, Issue:12 Topics: Adult; Aged; Anticholesteremic Agents; Arthralgia; Azetidines; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Headache; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Patient Dropouts; Pravastatin; Respiratory Tract Infections; Simvastatin; Sinusitis; Treatment Outcome; Triglycerides	2008
[Primary prevention trial by lowering hyperlipidemia on the cardiovascular disease (MEGA Study)]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2009, Volume: 46, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Cardiovascular Diseases; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin	2009
Effects of increasing the dose of pravastatin on serum adiponectin level in Japanese mild hypercholesterolemic and hypertensive patients. Arzneimittel-Forschung, 2009, Volume: 59, Issue:9 Topics: Adiponectin; Aged; Aged, 80 and over; Blood Pressure; C-Reactive Protein; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Japan; Lipids; Male; Middle Aged; Pravastatin; Prospective Studies	2009
Statins improve visual field alterations related to hypercholesterolemia. Atherosclerosis, 2010, Volume: 209, Issue:2 Topics: Adult; Anticholesteremic Agents; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diet, Fat-Restricted; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin; Triglycerides; Visual Fields	2010
Coronary heart disease in moderately hypercholesterolemic, hypertensive black and non-black patients randomized to pravastatin versus usual care: the antihypertensive and lipid lowering to prevent heart attack trial (ALLHAT-LLT). American heart journal, 2009, Volume: 158, Issue:6 Topics: Aged; Antihypertensive Agents; Black or African American; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Hypolipidemic Agents; Male; Middle Aged; Pravastatin; Severity of Illness Index	2009
Statins, antihypertensive treatment, and blood pressure control in clinic and over 24 hours: evidence from PHYLLIS randomised double blind trial. BMJ (Clinical research ed.), 2010, Mar-25, Volume: 340 Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Blood Pressure Determination; Drug Therapy, Combination; Female; Fosinopril; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Italy; Male; Middle Aged; Pravastatin	2010
Association between lowering low-density lipoprotein cholesterol with pravastatin and primary prevention of cardiovascular disease in mild to moderate hypercholesterolemic Japanese. Journal of atherosclerosis and thrombosis, 2010, Aug-31, Volume: 17, Issue:8 Topics: Adult; Aged; Asian People; Cardiovascular Diseases; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Risk Factors; Treatment Outcome	2010
Lifibrol as a model compound for a novel lipid-lowering mechanism of action. Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:4 Topics: Adult; Anticholesteremic Agents; Apolipoprotein B-100; Butanols; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Double-Blind Method; Humans; Hydroxybenzoates; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins, LDL; Male; Pravastatin; Triglycerides; Young Adult	2010
Obesity is associated with fatal coronary heart disease independently of traditional risk factors and deprivation. Heart (British Cardiac Society), 2011, Volume: 97, Issue:7 Topics: Body Mass Index; Coronary Disease; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Obesity; Poverty; Pravastatin; Risk Factors; Scotland	2011
Relationship between hemoglobin A1c and cardiovascular disease in mild-to-moderate hypercholesterolemic Japanese individuals: subanalysis of a large-scale randomized controlled trial. Cardiovascular diabetology, 2011, Jun-30, Volume: 10 Topics: Adult; Aged; Anticholesteremic Agents; Cardiovascular Diseases; Diet Therapy; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypercholesterolemia; Incidence; Japan; Lipids; Male; Middle Aged; Pravastatin; Risk Factors; Severity of Illness Index	2011
Low-dose pravastatin and age-related differences in risk factors for cardiovascular disease in hypercholesterolaemic Japanese: analysis of the management of elevated cholesterol in the primary prevention group of adult Japanese (MEGA study). Drugs & aging, 2011, Sep-01, Volume: 28, Issue:9 Topics: Adult; Age Factors; Aged; Asian People; Cardiovascular Diseases; Cholesterol; Coronary Disease; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Risk Factors; Stroke	2011
Effect of intensive lipid-lowering therapy with rosuvastatin on progression of carotid intima-media thickness in Japanese patients: Justification for Atherosclerosis Regression Treatment (JART) study. Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:1 Topics: Aged; Asian People; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; Female; Fluorobenzenes; Humans; Hypercholesterolemia; Hypolipidemic Agents; Japan; Longitudinal Studies; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrimidines; Rosuvastatin Calcium; Single-Blind Method; Sulfonamides; Time Factors; Treatment Outcome	2012
Usefulness of LDL-C-related parameters to predict cardiovascular risk and effect of pravastatin in mild-to-moderate hypercholesterolemia. Journal of atherosclerosis and thrombosis, 2012, Volume: 19, Issue:2 Topics: Adult; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies; Risk Factors; ROC Curve; Young Adult	2012
Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly. Atherosclerosis, 2012, Volume: 220, Issue:2 Topics: Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers; Cardiovascular Diseases; Chi-Square Distribution; Cholesterol, LDL; Europe; Female; Heterozygote; Homozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Linkage Disequilibrium; Liver X Receptors; Liver-Specific Organic Anion Transporter 1; Logistic Models; Male; Organic Anion Transporters; Orphan Nuclear Receptors; Phenotype; Polymorphism, Single Nucleotide; Pravastatin; Prospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome	2012
KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly. Atherosclerosis, 2012, Volume: 220, Issue:2 Topics: Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Cardiovascular Diseases; Chi-Square Distribution; Cholesterol, LDL; Europe; Female; Homozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kinesins; Linkage Disequilibrium; Lipoprotein(a); Male; Phenotype; Polymorphism, Single Nucleotide; Pravastatin; Prospective Studies; R-SNARE Proteins; Receptors, G-Protein-Coupled; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome	2012
Differential metabolic effects of rosuvastatin and pravastatin in hypercholesterolemic patients. International journal of cardiology, 2013, Jun-20, Volume: 166, Issue:2 Topics: Female; Fluorobenzenes; Glycated Hemoglobin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin Resistance; Male; Middle Aged; Pravastatin; Pyrimidines; Rosuvastatin Calcium; Single-Blind Method; Sulfonamides	2013
Double-dose pravastatin versus add-on ezetimibe with low-dose pravastatin - effects on LDL cholesterol, cholesterol absorption, and cholesterol synthesis in Japanese patients with hypercholesterolemia (PEAS study). Journal of atherosclerosis and thrombosis, 2012, Volume: 19, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Japan; Middle Aged; Patient Compliance; Pravastatin	2012
Pitavastatin shows greater lipid-lowering efficacy over 12 weeks than pravastatin in elderly patients with primary hypercholesterolaemia or combined (mixed) dyslipidaemia. European journal of preventive cardiology, 2013, Volume: 20, Issue:1 Topics: Aged; Aged, 80 and over; Cholesterol, LDL; Double-Blind Method; Drug Tolerance; Dyslipidemias; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Pravastatin; Quinolines; Time Factors; Treatment Outcome	2013
Effect of treatment with pravastatin or ezetimibe on endothelial function in patients with moderate hypercholesterolemia. European journal of clinical pharmacology, 2013, Volume: 69, Issue:3 Topics: Adult; Anticholesteremic Agents; Azetidines; Biomarkers; Brachial Artery; Cholesterol; Endothelium, Vascular; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Italy; Male; Middle Aged; Pravastatin; Severity of Illness Index; Treatment Outcome; Ultrasonography; Vasodilation	2013
Association of cholesteryl ester transfer protein mass with peripheral leukocyte count following statin therapy: a pilot study. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2012, Oct-01, Volume: 12, Issue:5 Topics: Aged; Atorvastatin; Cholesterol Ester Transfer Proteins; Cholesterol, LDL; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Leukocyte Count; Lipids; Male; Middle Aged; Multivariate Analysis; Pilot Projects; Pravastatin; Pyrroles; Regression Analysis; Risk Factors	2012
Pravastatin does not alter protease inhibitor exposure or virologic efficacy during a 24-week period of therapy. Journal of acquired immune deficiency syndromes (1999), 2002, Aug-01, Volume: 30, Issue:4 Topics: Anticholesteremic Agents; Antiretroviral Therapy, Highly Active; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Male; Pravastatin; Viremia	2002
Association of factor VII levels with inflammatory parameters in hypercholesterolemic patients. Atherosclerosis, 2002, Volume: 165, Issue:1 Topics: Adult; Aged; Analysis of Variance; Blood Coagulation Tests; Combined Modality Therapy; Coronary Disease; Diet, Fat-Restricted; Drug Administration Schedule; Factor VII; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Inflammation Mediators; Linear Models; Male; Middle Aged; Pravastatin; Probability; Reference Values; Risk Assessment; Risk Factors; Severity of Illness Index; Treatment Outcome	2002
Testing cognitive function in elderly populations: the PROSPER study. PROspective Study of Pravastatin in the Elderly at Risk. Journal of neurology, neurosurgery, and psychiatry, 2002, Volume: 73, Issue:4 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Neuropsychological Tests; Pravastatin; Prospective Studies; Reproducibility of Results	2002
Prognosis of hypercholesterolemic patients taking pravastatin for five years: the Chiba Lipid Intervention Program (CLIP) Study. Journal of atherosclerosis and thrombosis, 2002, Volume: 9, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Anticholesteremic Agents; Arrhythmias, Cardiac; Cause of Death; Female; Follow-Up Studies; Heart Failure; Humans; Hypercholesterolemia; Incidence; Lipids; Male; Middle Aged; Myocardial Infarction; Pravastatin; Prognosis; Prospective Studies; Risk Factors	2002
Health-related quality of life and long-term therapy with pravastatin and tocopherol (vitamin E) in older adults. Drugs & aging, 2002, Volume: 19, Issue:10 Topics: Aged; Aged, 80 and over; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged; Pravastatin; Quality of Life; Tocopherols; Triglycerides	2002
Pharmacokinetics of pravastatin in heart-transplant patients taking cyclosporin A. International journal of clinical pharmacology and therapeutics, 2002, Volume: 40, Issue:10 Topics: Anticholesteremic Agents; Cholesterol; Creatinine; Cyclosporine; Drug Interactions; Drug Monitoring; Female; Heart Transplantation; Humans; Hypercholesterolemia; Immunosuppressive Agents; L-Lactate Dehydrogenase; Male; Middle Aged; Pravastatin; Time Factors; Transferases; Triglycerides	2002
The anatomy of a clinical trial. The West of Scotland Coronary Prevention Study. Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2002, Volume: 11 Suppl 2 Topics: Aged; Anticholesteremic Agents; Cost of Illness; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Patient Compliance; Patient Selection; Pravastatin; Research Design; Risk Factors; Scotland; Treatment Outcome	2002
Association of pravastatin and left ventricular mass in hypercholesterolemic patients: role of 8-iso-prostaglandin f2alpha formation. Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:6 Topics: Anticholesteremic Agents; Blood Pressure; Dinoprost; Echocardiography; F2-Isoprostanes; Female; Humans; Hypercholesterolemia; Hypertrophy, Left Ventricular; Male; Middle Aged; Pravastatin	2002
[Comparative study of the impact of diet versus pravastatin on color vision in Brodman area 19 detected by computerized chromatic analysis (CARDIOCOLOUR Study)]. Revista espanola de cardiologia, 2002, Volume: 55, Issue:12 Topics: Adult; Aged; Anticholesteremic Agents; Cerebral Cortex; Color Perception; Color Perception Tests; Color Vision Defects; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin	2002
Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT). JAMA, 2002, Dec-18, Volume: 288, Issue:23 Topics: Aged; Anticholesteremic Agents; Cardiovascular Diseases; Cause of Death; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Lipids; Male; Middle Aged; Pravastatin; Proportional Hazards Models; Risk Factors	2002
Efficacy and safety of rosuvastatin compared with pravastatin and simvastatin in patients with hypercholesterolemia: a randomized, double-blind, 52-week trial. American heart journal, 2002, Volume: 144, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol, LDL; Double-Blind Method; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2002
Time-dependent effect of statins on platelet function in hypercholesterolaemia. European journal of clinical investigation, 2002, Volume: 32, Issue:12 Topics: Adult; Analysis of Variance; Antiporters; Atorvastatin; Blood Platelets; Case-Control Studies; Cholesterol; Cholesterol, LDL; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Linear Models; Lipoproteins, LDL; Male; Middle Aged; Nitric Oxide Synthase; P-Selectin; Platelet Activation; Pravastatin; Pyrroles; Simvastatin; Time Factors	2002
Increased levels of asymmetric dimethylarginine in populations at risk for atherosclerotic disease. Effects of pravastatin. Atherosclerosis, 2003, Volume: 166, Issue:2 Topics: Arginine; Arteriosclerosis; Cholesterol, LDL; Diabetes Mellitus, Type 1; Female; Humans; Hypercholesterolemia; Incidence; Male; Pravastatin; Predictive Value of Tests; Probability; Reference Values; Risk Assessment; Sensitivity and Specificity	2003
Levels of adhesion molecules do not decrease after 3 months of statin therapy in moderate hypercholesterolaemia. Clinical science (London, England : 1979), 2003, Volume: 104, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Cell Adhesion Molecules; Cholesterol; Cross-Sectional Studies; Double-Blind Method; E-Selectin; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Intercellular Adhesion Molecule-1; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Vascular Cell Adhesion Molecule-1	2003
Differing effects of low-dose estrogen-progestin therapy and pravastatin in postmenopausal hypercholesterolemic women. Climacteric : the journal of the International Menopause Society, 2002, Volume: 5, Issue:4 Topics: Aged; Anticholesteremic Agents; Brachial Artery; Cholesterol, HDL; Cholesterol, LDL; Diet, Reducing; Dose-Response Relationship, Drug; Double-Blind Method; Estradiol; Estrogen Replacement Therapy; Female; Fibrinogen; Humans; Hypercholesterolemia; Middle Aged; Norethindrone; Norethindrone Acetate; Postmenopause; Pravastatin; Progesterone Congeners; Quality of Life; Reference Values; Regional Blood Flow	2002
[The PROSPER Study (PROspective study of pravastatin in the elderly at risk)]. Revue medicale de Liege, 2002, Volume: 57, Issue:12 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Male; Pravastatin; Risk Factors	2002
Simvastatin and pravastatin equally improve flow-mediated dilation in males with hypercholesterolemia. Wiener klinische Wochenschrift, 2002, Dec-30, Volume: 114, Issue:23-24 Topics: Anticholesteremic Agents; Brachial Artery; Cholesterol; Cholesterol, HDL; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Simvastatin; Time Factors; Treatment Outcome; Triglycerides; Ultrasonography; Vasodilation	2002
Comparison of the effect of two HMG CoA reductase inhibitors on LDL susceptibility to oxidation. Arquivos brasileiros de cardiologia, 2003, Volume: 80, Issue:2 Topics: Adult; Aged; Antioxidants; Coronary Artery Disease; Double-Blind Method; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lipids; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Pravastatin	2003
Efficacy of rosuvastatin compared with other statins at selected starting doses in hypercholesterolemic patients and in special population groups. The American journal of cardiology, 2003, Mar-06, Volume: 91, Issue:5A Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Drug Administration Schedule; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Least-Squares Analysis; Male; Middle Aged; Multicenter Studies as Topic; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2003
Guidelines for lowering lipids to reduce coronary artery disease risk: a comparison of rosuvastatin with atorvastatin, pravastatin, and simvastatin for achieving lipid-lowering goals. The American journal of cardiology, 2003, Mar-06, Volume: 91, Issue:5A Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Drug Administration Schedule; Europe; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Multicenter Studies as Topic; Practice Guidelines as Topic; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Risk; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2003
Lipid and apolipoprotein ratios: association with coronary artery disease and effects of rosuvastatin compared with atorvastatin, pravastatin, and simvastatin. The American journal of cardiology, 2003, Mar-06, Volume: 91, Issue:5A Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Europe; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Least-Squares Analysis; Lipids; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2003
[Clinical study of the month. The ALLHAT-LLT trial]. Revue medicale de Liege, 2003, Volume: 58, Issue:1 Topics: Aged; Anticholesteremic Agents; Cardiovascular Diseases; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Pravastatin; Randomized Controlled Trials as Topic; Risk Factors	2003
An economic analysis of the Atorvastatin Comparative Cholesterol Efficacy and Safety Study (ACCESS). PharmacoEconomics, 2003, Volume: 21 Suppl 1 Topics: Adult; Aged; Atorvastatin; Cholesterol, LDL; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Pravastatin; Pyrroles; Risk Factors; Simvastatin; Treatment Outcome	2003
Results of two clinical trials on the safety and efficacy of pravastatin 80 and 160 mg per day. The American journal of cardiology, 2003, Apr-01, Volume: 91, Issue:7 Topics: Adolescent; Adult; Aged; Alanine Transaminase; Apolipoprotein A-I; Apolipoproteins B; Biomarkers; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Creatine Kinase; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Liver Function Tests; Male; Middle Aged; Patient Compliance; Pravastatin; Treatment Outcome; Triglycerides; United States	2003
Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. European heart journal, 2003, Volume: 24, Issue:8 Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Double-Blind Method; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin; Treatment Outcome; Vitamins	2003
Effects of cholesterol-lowering therapy on pressor hyperreactivity to stress in hypercholesterolemic patients. Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:4 Topics: Anticholesteremic Agents; Blood Platelets; Blood Pressure; Calcium; Catecholamines; Cyclic GMP; Female; Hand Strength; Heart Rate; Humans; Hypercholesterolemia; Lipid Peroxides; Lipids; Male; Middle Aged; Nitric Oxide; Pravastatin; Stress, Psychological	2003
Effects of simvastatin and pravastatin on peroxidation of erythrocyte plasma membrane lipids in patients with type 2 hypercholesterolemia. Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:5 Topics: Adult; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; Hypercholesterolemia; Lipid Peroxidation; Membrane Fluidity; Membrane Lipids; Middle Aged; Pravastatin; Simvastatin; Triglycerides	2003
Reduction in serum total cholesterol and risks of coronary events and cerebral infarction in Japanese men: the Kyushu Lipid Intervention Study. Circulation journal : official journal of the Japanese Circulation Society, 2003, Volume: 67, Issue:6 Topics: Aged; Anticholesteremic Agents; Cerebral Infarction; Cholesterol; Coronary Disease; Humans; Hypercholesterolemia; Japan; Male; Middle Aged; Myocardial Infarction; Pravastatin; Proportional Hazards Models; Risk; Treatment Outcome	2003
Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial). The American journal of cardiology, 2003, Jul-15, Volume: 92, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Atorvastatin; Cholesterol, LDL; Dose-Response Relationship, Drug; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Time Factors	2003
[Markers of inflammation and platelet aggregation in patients with non ST elevation acute coronary syndrome treated with atorvastatin or pravastatin]. Kardiologiia, 2003, Volume: 43, Issue:1 Topics: Acute Disease; Adult; Aged; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Coronary Disease; Drug Administration Schedule; Electrocardiography; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Male; Middle Aged; Platelet Aggregation; Pravastatin; Pyrroles; Time Factors	2003
Statins reduce oxidized low-density lipoprotein levels, but do not alter soluble intercellular cell-adhesion molecule-1 and vascular cell-adhesion molecule-1 levels in subjects with hypercholesterolaemia. Clinical science (London, England : 1979), 2004, Volume: 106, Issue:2 Topics: Adult; Aged; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Simvastatin; Vascular Cell Adhesion Molecule-1	2004
Effects of eicosapentaenoic acid on cardiovascular events in Japanese patients with hypercholesterolemia: rationale, design, and baseline characteristics of the Japan EPA Lipid Intervention Study (JELIS). American heart journal, 2003, Volume: 146, Issue:4 Topics: Adult; Aged; Angina, Unstable; Anticholesteremic Agents; Chemotherapy, Adjuvant; Coronary Artery Disease; Death, Sudden, Cardiac; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Japan; Male; Middle Aged; Myocardial Infarction; Pravastatin; Prospective Studies; Simvastatin	2003
Effects of atorvastatin and pravastatin on malondialdehyde-modified LDL in hypercholesterolemic patients. Circulation journal : official journal of the Japanese Circulation Society, 2003, Volume: 67, Issue:10 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, HDL; Cross-Over Studies; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Pravastatin; Pyrroles	2003
Different effects of simvastatin and pravastatin on adrenal sensitivity to angiotensin II. British journal of clinical pharmacology, 2003, Volume: 56, Issue:6 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Cross-Over Studies; Diuretics; Female; Furosemide; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Simvastatin	2003
Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals: results from the STELLAR trial. Current medical research and opinion, 2003, Volume: 19, Issue:8 Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; North America; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2003
Does statin therapy influence steroid hormone synthesis? Zeitschrift fur Kardiologie, 2004, Volume: 93, Issue:1 Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Dehydroepiandrosterone Sulfate; Double-Blind Method; Estradiol; Female; Follicle Stimulating Hormone; Hormones; Humans; Hydrocortisone; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Luteinizing Hormone; Male; Middle Aged; Pravastatin; Reference Values; Testosterone	2004
Monocyte chemoattractant protein-1 and CC-chemokine receptor-2 in severe hypercholesterolaemia. Scandinavian journal of clinical and laboratory investigation, 2003, Volume: 63, Issue:7-8 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; C-Reactive Protein; Chemokine CCL2; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Female; Gene Expression; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Receptors, CCR2; Receptors, Chemokine; Single-Blind Method; Triglycerides	2003
Effects of pravastatin on lipoproteins and endothelial function in patients receiving human immunodeficiency virus protease inhibitors. American heart journal, 2004, Volume: 147, Issue:4 Topics: Adult; Brachial Artery; Cholesterol; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Lipoproteins; Male; Pravastatin; Reverse Transcriptase Inhibitors; Triglycerides; Ultrasonography; Vasodilation	2004
Effects of switching statins on achievement of lipid goals: Measuring Effective Reductions in Cholesterol Using Rosuvastatin Therapy (MERCURY I) study. American heart journal, 2004, Volume: 147, Issue:4 Topics: Aged; Arteriosclerosis; Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Diabetes Mellitus, Type 2; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Logistic Models; Male; Middle Aged; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Triglycerides	2004
Impaired myocardial vasodilatation during hyperaemic stress is improved by simvastatin but not by pravastatin in patients with hypercholesterolaemia. European heart journal, 2004, Volume: 25, Issue:8 Topics: Anticholesteremic Agents; Coronary Vessels; Female; Humans; Hypercholesterolemia; Hyperemia; Hypolipidemic Agents; Male; Myocardium; Pravastatin; Simvastatin; Stress, Physiological; Tomography, Emission-Computed; Vasodilation	2004
[Clinical study of the month. REVERAL and PROVE-IT: confirmation of the concept " the lower, the better" for cholesterol therapy in patients with coronary heart disease]. Revue medicale de Liege, 2004, Volume: 59, Issue:3 Topics: Anticholesteremic Agents; Atorvastatin; Coronary Artery Disease; Coronary Disease; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hypercholesterolemia; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic	2004
Interleukin-6, fibrin D-dimer, and coagulation factors VII and XIIa in prediction of coronary heart disease. Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:8 Topics: Angioplasty, Balloon, Coronary; Biomarkers; Case-Control Studies; Coronary Disease; Factor VII; Factor XIIa; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Incidence; Inflammation; Interleukin-6; Male; Middle Aged; Monocytes; Myocardial Infarction; Myocardial Revascularization; Pravastatin; Predictive Value of Tests; Risk Factors; Scotland; Thrombophilia; Triglycerides	2004
Lipid lowering therapy with fluvastatin and pravastatin in patients with HIV infection and antiretroviral therapy: comparison of efficacy and interaction with indinavir. Infection, 2004, Volume: 32, Issue:4 Topics: Adult; Anticholesteremic Agents; Antiretroviral Therapy, Highly Active; Fatty Acids, Monounsaturated; Female; Fluvastatin; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Indinavir; Indoles; Male; Middle Aged; Pravastatin; Prospective Studies; Treatment Outcome	2004
Different effects of antihypertensive regimens based on fosinopril or hydrochlorothiazide with or without lipid lowering by pravastatin on progression of asymptomatic carotid atherosclerosis: principal results of PHYLLIS--a randomized double-blind trial. Stroke, 2004, Volume: 35, Issue:12 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Antihypertensive Agents; Carotid Stenosis; Disease Progression; Diuretics; Drug Therapy, Combination; Female; Fosinopril; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Pravastatin; Sodium Chloride Symporter Inhibitors	2004
Effects of rosuvastatin versus atorvastatin, simvastatin, and pravastatin on non-high-density lipoprotein cholesterol, apolipoproteins, and lipid ratios in patients with hypercholesterolemia: additional results from the STELLAR trial. Clinical therapeutics, 2004, Volume: 26, Issue:9 Topics: Aged; Anticholesteremic Agents; Apolipoproteins; Atorvastatin; Cholesterol, LDL; Dose-Response Relationship, Drug; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2004
Looking for prognostic information in the ST-T segment--is it really worth it? Journal of electrocardiology, 2004, Volume: 37 Suppl Topics: Age Factors; Anticholesteremic Agents; Cause of Death; Cohort Studies; Double-Blind Method; Electrocardiography; Follow-Up Studies; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Logistic Models; Male; Middle Aged; Myocardial Infarction; Placebos; Pravastatin; Predictive Value of Tests; Prognosis; Risk Assessment; Signal Processing, Computer-Assisted; Smoking	2004
Atorvastatin and pravastatin elevated pre-heparin lipoprotein lipase mass of type 2 diabetes with hypercholesterolemia. Journal of atherosclerosis and thrombosis, 2004, Volume: 11, Issue:6 Topics: Anticholesteremic Agents; Atorvastatin; Diabetes Mellitus, Type 2; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein Lipase; Middle Aged; Pravastatin; Pyrroles	2004
Effects of statins on circulating oxidized low-density lipoprotein in patients with hypercholesterolemia. Japanese heart journal, 2004, Volume: 45, Issue:6 Topics: Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Prospective Studies	2004
Rosuvastatin is cost-effective in treating patients to low-density lipoprotein-cholesterol goals compared with atorvastatin, pravastatin and simvastatin: analysis of the STELLAR trial. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2005, Volume: 12, Issue:1 Topics: Atorvastatin; Cardiovascular Diseases; Cholesterol, LDL; Cost-Benefit Analysis; Drug Costs; Economics, Pharmaceutical; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Pyrimidines; Pyrroles; Retrospective Studies; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2005
A comparative crossover study of the effects of fluvastatin and pravastatin (FP-COS) on circulating autoantibodies to oxidized LDL in patients with hypercholesterolemia. Journal of atherosclerosis and thrombosis, 2005, Volume: 12, Issue:1 Topics: Autoantibodies; Cross-Over Studies; Enzyme-Linked Immunosorbent Assay; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lipoproteins, LDL; Pravastatin	2005
Effects of switching statins on lipid and apolipoprotein ratios in the MERCURY I study. International journal of cardiology, 2005, Apr-20, Volume: 100, Issue:2 Topics: Analysis of Variance; Apolipoproteins; Atorvastatin; Coronary Disease; Dose-Response Relationship, Drug; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin; Pyrimidines; Pyrroles; Risk; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2005
A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial. Mayo Clinic proceedings, 2005, Volume: 80, Issue:5 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Nephelometry and Turbidimetry; Practice Guidelines as Topic; Pravastatin; Pyrroles; Retrospective Studies; Risk Factors; Simvastatin	2005
Relative efficacy of atorvastatin 80 mg and pravastatin 40 mg in achieving the dual goals of low-density lipoprotein cholesterol <70 mg/dl and C-reactive protein <2 mg/l: an analysis of the PROVE-IT TIMI-22 trial. Journal of the American College of Cardiology, 2005, May-17, Volume: 45, Issue:10 Topics: Administration, Oral; Aged; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Cholesterol, LDL; Cohort Studies; Coronary Restenosis; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Follow-Up Studies; Gatifloxacin; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Pravastatin; Pyrroles; Secondary Prevention; Statistics as Topic; Survival Rate; Treatment Outcome	2005
Baseline levels of low-density lipoprotein cholesterol and lipoprotein (a) and the AvaII polymorphism of the low-density lipoprotein receptor gene influence the response of low-density lipoprotein cholesterol to pravastatin treatment. Metabolism: clinical and experimental, 2005, Volume: 54, Issue:6 Topics: Adult; Aged; Cholesterol, LDL; Deoxyribonucleases, Type II Site-Specific; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein(a); Male; Middle Aged; Polymorphism, Genetic; Pravastatin; Prospective Studies; Receptors, LDL	2005
The effect of statin therapy on lipoprotein associated phospholipase A2 levels. Atherosclerosis, 2005, Volume: 182, Issue:1 Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Aged; Anticholesteremic Agents; Biomarkers; Coronary Artery Disease; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Phospholipases A; Phospholipases A2; Pravastatin; Regression Analysis; Risk Factors	2005
HMG-CoA reductase inhibitors suppress the development and progression of carotid artery intimal-medial thickening in hypercholesterolemic type 2 diabetic patients. Journal of atherosclerosis and thrombosis, 2005, Volume: 12, Issue:3 Topics: Aged; Carotid Artery, Common; Cholesterol; Diabetes Mellitus, Type 2; Drug Administration Schedule; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Simvastatin; Tunica Intima; Tunica Media	2005
Short-term reduction in bone markers with high-dose simvastatin. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2005, Volume: 16, Issue:10 Topics: Adult; Alkaline Phosphatase; Biomarkers; Bone Remodeling; Collagen; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Osteocalcin; Pravastatin; Simvastatin	2005
The -514C/T polymorphism of the hepatic lipase gene significantly modulates the HDL-cholesterol response to statin treatment. Atherosclerosis, 2005, Volume: 182, Issue:1 Topics: Aged; Anticholesteremic Agents; Cholesterol, HDL; Drug Resistance; Female; Humans; Hypercholesterolemia; Lipase; Male; Middle Aged; Polymorphism, Genetic; Pravastatin; Prospective Studies	2005
Beneficial effects of atorvastatin on sd LDL and LDL phenotype B in statin-naive patients and patients previously treated with simvastatin or pravastatin. International journal of cardiology, 2005, Oct-10, Volume: 104, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Coronary Disease; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrroles; Simvastatin; Treatment Outcome; Triglycerides	2005
Achieving lipid goals in real life: the Dutch DISCOVERY study. International journal of clinical practice, 2005, Volume: 59, Issue:12 Topics: Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Netherlands; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome; Triglycerides	2005
Preoperative statin therapy and troponin T predict early complications of coronary artery surgery. The Annals of thoracic surgery, 2006, Volume: 81, Issue:1 Topics: Aged; Atorvastatin; Biomarkers; C-Reactive Protein; Comorbidity; Coronary Artery Bypass; Creatine Kinase, MB Form; Female; Heptanoic Acids; Hospital Mortality; Hospitals, University; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Interleukin-6; Lipids; Male; Middle Aged; Myocardial Infarction; Postoperative Complications; Pravastatin; Premedication; Preoperative Care; Prospective Studies; Pyrroles; Risk Assessment; Simvastatin; Systemic Inflammatory Response Syndrome; Troponin T	2006
Comparison of effects of pravastatin and hormone therapy on soluble P-selectin and platelet P-selectin expression in postmenopausal hypercholesterolemic women. Maturitas, 2006, Jan-20, Volume: 53, Issue:2 Topics: Aged; Anticholesteremic Agents; Blood Platelets; Double-Blind Method; Estradiol; Estrogen Replacement Therapy; Fasting; Female; Humans; Hypercholesterolemia; Lipids; Middle Aged; Norethindrone; P-Selectin; Postmenopause; Pravastatin; Regression Analysis; Treatment Outcome	2006
The ability of statins to protect low density lipoprotein from oxidation in hypercholesterolemic patients. International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:12 Topics: Anticholesteremic Agents; Atorvastatin; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Pravastatin; Pyrroles; Simvastatin; Thiobarbituric Acid Reactive Substances	2005
Ezetimibe for the treatment of uncontrolled hypercholesterolemia in patients with high-dose statin therapy after renal transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2006, Volume: 6, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Cyclosporine; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Kidney Transplantation; Liver; Male; Middle Aged; Muscle, Skeletal; Pravastatin; Simvastatin; Tacrolimus	2006
[Erythrocyte fluidity in patients with hyperlipidemia during statins therapy]. Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 113, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Erythrocyte Membrane; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipid Peroxidation; Male; Membrane Fluidity; Membrane Lipids; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Statistics, Nonparametric; Triglycerides	2005
Effect of pravastatin on body composition and markers of cardiovascular disease in HIV-infected men--a randomized, placebo-controlled study. AIDS (London, England), 2006, Apr-24, Volume: 20, Issue:7 Topics: Adipose Tissue; Antiretroviral Therapy, Highly Active; Biomarkers; Blood Glucose; Body Composition; Cardiovascular Diseases; Cholesterol; Diet; Double-Blind Method; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin; Male; Middle Aged; Pilot Projects; Pravastatin; Triglycerides	2006
Effect of probucol on elderly hypercholesterolemic patients in the FAST study. Fukuoka igaku zasshi = Hukuoka acta medica, 2006, Volume: 97, Issue:1 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Carotid Arteries; Carotid Artery Diseases; Cohort Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Male; Middle Aged; Pravastatin; Probucol; Risk; Treatment Outcome	2006
Endothelial Protection, AT1 blockade and Cholesterol-Dependent Oxidative Stress: the EPAS trial. Circulation, 2006, Jul-04, Volume: 114, Issue:1 Suppl Topics: Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Biphenyl Compounds; Blood Pressure; Cholesterol; Cholesterol, LDL; Coronary Artery Bypass; Coronary Disease; Drug Therapy, Combination; Elective Surgical Procedures; Gene Expression Regulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Irbesartan; Mammary Arteries; Membrane Glycoproteins; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Natriuretic Peptide, C-Type; Nitric Oxide Synthase Type III; Oxidative Stress; Polymerase Chain Reaction; Pravastatin; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Scavenger Receptors, Class E; Tetrazoles	2006
Treatment of hypercholesterolemia in patients with metabolic syndrome: how do different statins compare? Nature clinical practice. Endocrinology & metabolism, 2006, Volume: 2, Issue:3 Topics: Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Metabolic Syndrome; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2006
Pravastatin decreases blood pressure in hypertensive and hypercholesterolemic patients receiving antihypertensive treatment. Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:9 Topics: Adult; Aged; Anticholesteremic Agents; Blood Pressure; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Pravastatin; Retrospective Studies	2006
Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomised controlled trial. Lancet (London, England), 2006, Sep-30, Volume: 368, Issue:9542 Topics: Adult; Aged; Anticholesteremic Agents; Cardiovascular Diseases; Diet, Fat-Restricted; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Japan; Male; Middle Aged; Pravastatin	2006
Effect of colestimide therapy for glycemic control in type 2 diabetes mellitus with hypercholesterolemia. Endocrine journal, 2007, Volume: 54, Issue:1 Topics: Aged; Anticholesteremic Agents; Blood Glucose; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Glycated Hemoglobin; Hemoglobins; Humans; Hypercholesterolemia; Imidazoles; Insulin Resistance; Male; Middle Aged; Pravastatin; Resins, Synthetic	2007
Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid. Journal of Alzheimer's disease : JAD, 2006, Volume: 10, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Brain; Cholesterol; Cholesterol, LDL; F2-Isoprostanes; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Neuroprotective Agents; Peptide Fragments; Pravastatin; Simvastatin; tau Proteins; Triglycerides	2006
A pravastatin dose-escalation study in systemic lupus erythematosus. Rheumatology international, 2007, Volume: 27, Issue:11 Topics: Adult; Body Mass Index; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Synergism; Female; Glucocorticoids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lupus Erythematosus, Systemic; Middle Aged; Pravastatin	2007
Preferable effect of pravastatin compared to atorvastatin on beta cell function in Japanese early-state type 2 diabetes with hypercholesterolemia. Endocrine journal, 2007, Volume: 54, Issue:3 Topics: Atorvastatin; Cross-Over Studies; Diabetes Mellitus, Type 2; Glucose Intolerance; Glucose Tolerance Test; Heptanoic Acids; Humans; Hypercholesterolemia; Insulin-Secreting Cells; Japan; Patient Compliance; Pravastatin; Pyrroles	2007
Difference in early effects of statin therapy on coronary and forearm flow reserve in postmenopausal hypercholesterolemic women. Circulation journal : official journal of the Japanese Circulation Society, 2007, Volume: 71, Issue:6 Topics: Anticholesteremic Agents; Cholesterol; Coronary Circulation; Female; Forearm; Humans; Hypercholesterolemia; Middle Aged; Plethysmography; Postmenopause; Pravastatin; Prospective Studies; Regional Blood Flow; Time Factors	2007
Statin's cost-effectiveness: a Canadian analysis of commonly prescribed generic and brand name statins. The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2007,Summer, Volume: 14, Issue:2 Topics: Adult; Atorvastatin; Canada; Cholesterol, LDL; Cost-Benefit Analysis; Drug Costs; Drugs, Generic; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insurance, Pharmaceutical Services; Male; Models, Economic; Practice Guidelines as Topic; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2007
Primary prevention of cardiovascular diseases among hypercholesterolemic Japanese with a low dose of pravastatin. Atherosclerosis. Supplements, 2007, Volume: 8, Issue:2 Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Japan; Male; Middle Aged; Patient Selection; Practice Guidelines as Topic; Pravastatin; Prospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome	2007
Efficacy and safety of high-dose pravastatin in hypercholesterolemic patients with well-compensated chronic liver disease: Results of a prospective, randomized, double-blind, placebo-controlled, multicenter trial. Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Chronic Disease; Double-Blind Method; Female; Humans; Hypercholesterolemia; Liver; Liver Diseases; Male; Middle Aged; Pravastatin; Treatment Outcome; Triglycerides	2007
Decreased plasma soluble RAGE in patients with hypercholesterolemia: effects of statins. Free radical biology & medicine, 2007, Nov-01, Volume: 43, Issue:9 Topics: Anticholesteremic Agents; Arginine; Atherosclerosis; Atorvastatin; Cross-Sectional Studies; Dinoprost; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Pravastatin; Pyrroles; Receptor for Advanced Glycation End Products; Receptors, Immunologic	2007
Long-term follow-up of the West of Scotland Coronary Prevention Study. The New England journal of medicine, 2007, Oct-11, Volume: 357, Issue:15 Topics: Anticholesteremic Agents; Coronary Disease; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Pravastatin	2007
Phytosterols dissolved in diacylglycerol oil reinforce the cholesterol-lowering effect of low-dose pravastatin treatment. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2008, Volume: 18, Issue:7 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Diglycerides; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Female; Humans; Hypercholesterolemia; Lipoprotein(a); Male; Middle Aged; Phytosterols; Pravastatin; Solubility; Treatment Outcome; Triglycerides	2008
Usefulness of pravastatin in primary prevention of cardiovascular events in women: analysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA study). Circulation, 2008, Jan-29, Volume: 117, Issue:4 Topics: Adult; Age Factors; Aged; Cardiovascular Diseases; Cerebral Infarction; Coronary Artery Disease; Diet Therapy; Disease Management; Female; Humans; Hypercholesterolemia; Incidence; Japan; Lipids; Male; Middle Aged; Pravastatin; Sex Factors	2008
Early Improvements in insulin sensitivity and inflammatory markers are induced by pravastatin in nondiabetic subjects with hypercholesterolemia. Clinica chimica acta; international journal of clinical chemistry, 2008, Volume: 390, Issue:1-2 Topics: Anticholesteremic Agents; Cholesterol; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation; Insulin Resistance; Male; Middle Aged; Pravastatin; Triglycerides	2008
Statin therapy increases carotid plaque echogenicity in hypercholesterolemic patients. Ultrasound in medicine & biology, 2008, Volume: 34, Issue:9 Topics: Aged; Atorvastatin; Biomarkers; C-Reactive Protein; Carotid Arteries; Carotid Stenosis; Cholesterol; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Interleukin-18; Interleukin-6; Male; Middle Aged; Pravastatin; Probability; Prospective Studies; Pyrroles; Simvastatin; Triglycerides; Tunica Intima; Ultrasonography	2008
Reduction of charge-modified LDL by statin therapy in patients with CHD or CHD risk factors and elevated LDL-C levels: the SPECIAL Study. Atherosclerosis, 2008, Volume: 201, Issue:2 Topics: Aged; Anticholesteremic Agents; C-Reactive Protein; Cholesterol, LDL; Coronary Disease; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Risk Factors; Simvastatin; Treatment Outcome; Triglycerides	2008
Effects of atorvastatin and pravastatin on glucose tolerance, adipokine levels and inflammatory markers in hypercholesterolaemic patients. Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:9 Topics: Adipokines; Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; Blood Glucose; Cross-Over Studies; Female; Glucose Intolerance; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Male; Middle Aged; Pravastatin; Pyrroles	2008
Changes in plasma lipids, lipoproteins and apolipoproteins in hypercholesterolaemic patients treated with pravastatin. Journal of human hypertension, 1995, Volume: 9, Issue:7 Topics: Apolipoproteins; Cholesterol; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Male; Middle Aged; Phosphatidylcholine-Sterol O-Acyltransferase; Phospholipids; Pravastatin; Triglycerides	1995
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. The New England journal of medicine, 1995, Nov-16, Volume: 333, Issue:20 Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Humans; Hypercholesterolemia; Incidence; Male; Middle Aged; Myocardial Infarction; Neoplasms; Pravastatin; Risk; Survival Analysis	1995
Efficacy and safety of pravastatin in the treatment of patients with type I or type II diabetes mellitus and hypercholesterolemia. The American journal of medicine, 1995, Volume: 99, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Postmenopause; Pravastatin; Treatment Outcome	1995
Effects of bezafibrate and of 2 HMG-CoA reductase inhibitors on lipoprotein (a) level in hypercholesterolemic patients. International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:6 Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Bezafibrate; Cholesterol; Delayed-Action Preparations; Diet; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipoprotein(a); Lovastatin; Male; Middle Aged; Pravastatin; Receptors, LDL; Simvastatin	1995
Comparison of fluvastatin versus pravastatin treatment of primary hypercholesterolemia. French Fluvastatin Study Group. The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2 Topics: Adult; Aged; Alanine Transaminase; Anticholesteremic Agents; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatine Kinase; Double-Blind Method; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Male; Middle Aged; Placebos; Pravastatin; Triglycerides	1995
Effects of fluvastatin and pravastatin on lipid profiles and thromboxane production in type IIa hypercholesterolemia. The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2 Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lipids; Male; Middle Aged; Placebos; Pravastatin; Single-Blind Method; Thromboxane A2; Thromboxane B2; Thromboxanes; Triglycerides	1995
Effects of treatment with simvastatin and pravastatin on cognitive function in patients with hypercholesterolaemia. British journal of clinical pharmacology, 1995, Volume: 39, Issue:3 Topics: Adult; Anticholesteremic Agents; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin	1995
Effect of pravastatin on outcomes after cardiac transplantation. The New England journal of medicine, 1995, Sep-07, Volume: 333, Issue:10 Topics: Cholesterol; Coronary Disease; Coronary Vessels; Cytotoxicity, Immunologic; Female; Graft Rejection; Heart Transplantation; Humans; Hypercholesterolemia; Incidence; Killer Cells, Natural; Male; Middle Aged; Pravastatin; Prospective Studies; Survival Rate; Ultrasonography, Interventional	1995
Effect of pravastatin in the treatment of hypercholesterolemia after renal transplantation under cyclosporine and prednisone. Transplantation proceedings, 1995, Volume: 27, Issue:4 Topics: Adult; Apolipoprotein A-I; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cyclosporine; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Immunosuppression Therapy; Kidney Transplantation; Male; Middle Aged; Muromonab-CD3; Pravastatin; Prednisone	1995
[Effect of pravastatin on hypercholesterolemia associated with proteinuria]. Anales de medicina interna (Madrid, Spain : 1984), 1994, Volume: 11, Issue:11 Topics: Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Proteinuria	1994
Kuopio Atherosclerosis Prevention Study (KAPS). A population-based primary preventive trial of the effect of LDL lowering on atherosclerotic progression in carotid and femoral arteries. Circulation, 1995, Oct-01, Volume: 92, Issue:7 Topics: Anticholesteremic Agents; Arteriosclerosis; Carotid Artery Diseases; Carotid Artery, Common; Cholesterol, LDL; Cohort Studies; Double-Blind Method; Femoral Artery; Finland; Humans; Hypercholesterolemia; Intracranial Arteriosclerosis; Lipids; Male; Middle Aged; Pravastatin; Risk Factors; Smoking; Time Factors; Ultrasonography; Vitamin E	1995
Efficacy and safety of pravastatin in African Americans with primary hypercholesterolemia. Archives of internal medicine, 1995, Sep-25, Volume: 155, Issue:17 Topics: Anticholesteremic Agents; Black People; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin	1995
Beneficial effect of cholesterol-lowering therapy on endothelium-dependent coronary vasodilation in patients with hypercholesterolemia. Annals of the New York Academy of Sciences, 1995, Jan-17, Volume: 748 Topics: Acetylcholine; Coronary Vessels; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Nitrates; Papaverine; Pravastatin; Vasodilation	1995
Short term effects of pravastatin on blood pressure in hypercholesterolaemic hypertensive patients. Blood pressure, 1994, Volume: 3, Issue:6 Topics: Blood Pressure; Captopril; Cholesterol; Cholesterol, LDL; Combined Modality Therapy; Double-Blind Method; Drug Interactions; Felodipine; Female; Humans; Hypercholesterolemia; Hypertension; Lipids; Male; Middle Aged; Pravastatin	1994
A comparison of the effects of simvastatin and pravastatin monotherapy on muscle histology and permeability in hypercholesterolaemic patients. British journal of clinical pharmacology, 1995, Volume: 39, Issue:2 Topics: Adult; Anticholesteremic Agents; Double-Blind Method; Ergometry; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Muscles; Permeability; Pravastatin; Prospective Studies; Simvastatin; Statistics as Topic	1995
[Randomized, double-blind comparative study between pravastatin and lovastatin. Evaluation of efficacy and safety]. Arquivos brasileiros de cardiologia, 1994, Volume: 63, Issue:4 Topics: Adult; Aged; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin	1994
Long-term efficacy and tolerability of pravastatin in hypercholesterolemia in patients with non-insulin-dependent diabetes mellitus. Hyogo Pravastatin Study Group. Diabetes research and clinical practice, 1995, Volume: 27, Issue:1 Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Time Factors; Triglycerides	1995
Effects of treatment with lovastatin and pravastatin on daytime cognitive performance. Clinical cardiology, 1995, Volume: 18, Issue:4 Topics: Adult; Affect; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin	1995
Central nervous system effects of HMG CoA reductase inhibitors: lovastatin and pravastatin on sleep and cognitive performance in patients with hypercholesterolemia. Journal of clinical pharmacology, 1994, Volume: 34, Issue:10 Topics: Adult; Affect; Aged; Cholesterol, LDL; Cognition; Cross-Over Studies; Double-Blind Method; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Polysomnography; Pravastatin; Psychomotor Performance; Sleep	1994
Improvement of glucose tolerance by bezafibrate in non-obese patients with hyperlipidemia and impaired glucose tolerance. Diabetes research and clinical practice, 1994, Volume: 25, Issue:3 Topics: Bezafibrate; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Follow-Up Studies; Glucose Intolerance; Glucose Tolerance Test; Humans; Hypercholesterolemia; Hyperlipidemias; Insulin; Male; Middle Aged; Pravastatin	1994
Efficacy of pravastatin in combination with captopril in hypertensive patients. The Medical journal of Australia, 1995, Feb-20, Volume: 162, Issue:4 Topics: Adult; Aged; Analysis of Variance; Captopril; Cholesterol; Double-Blind Method; Drug Therapy, Combination; Humans; Hypercholesterolemia; Hypertension; Middle Aged; Pravastatin; Treatment Outcome	1995
Abnormal lipoprotein (a) and lipid profiles in renal allograft recipients: effects of treatment with pravastatin. Transplantation proceedings, 1995, Volume: 27, Issue:1 Topics: Adult; Apolipoproteins A; Apolipoproteins B; Cholesterol; Female; Humans; Hypercholesterolemia; Kidney Transplantation; Lipoprotein(a); Lipoproteins, HDL; Lipoproteins, LDL; Male; Pravastatin; Transplantation, Homologous; Triglycerides	1995
A multi-centre study of the efficacy and safety of pravastatin in hypercholesterolaemic patients with non-insulin-dependent diabetes mellitus. Current medical research and opinion, 1994, Volume: 13, Issue:4 Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin	1994
Effects of pravastatin on cardiovascular reactivity to norepinephrine and angiotensin II in patients with hypercholesterolemia and systemic hypertension. The American journal of cardiology, 1995, Mar-15, Volume: 75, Issue:8 Topics: Adult; Aged; Angiotensin II; Blood Pressure; Cardiovascular System; Cholesterol; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Norepinephrine; Pravastatin; Treatment Outcome	1995
Pravastatin inhibits cellular cholesterol synthesis and increases low density lipoprotein receptor activity in macrophages: in vitro and in vivo studies. British journal of clinical pharmacology, 1994, Volume: 38, Issue:6 Topics: Adult; Animals; Anticholesteremic Agents; Cholesterol; Dose-Response Relationship, Drug; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins, LDL; Macrophages; Male; Mice; Middle Aged; Pravastatin; Radioimmunoassay; Receptors, LDL	1994
Efficacy and safety of pravastatin in hypertensive hypercholesterolaemic patients on antihypertensive drug therapy. Journal of human hypertension, 1994, Volume: 8, Issue:7 Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Cholesterol; Double-Blind Method; Drug Interactions; Female; Humans; Hypercholesterolemia; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Patient Compliance; Pravastatin	1994
Clinical efficacy and pharmacokinetics of HMG-CoA reductase inhibitors in heart transplant patients treated with cyclosporin A. Transplantation proceedings, 1994, Volume: 26, Issue:5 Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Creatinine; Cyclosporine; Follow-Up Studies; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin; Time Factors; Triglycerides	1994
Comparative efficacy and tolerability of 5 and 10 mg simvastatin and 10 mg pravastatin in moderate primary hypercholesterolemia. Simvastatin Pravastatin European Study Group. Cardiology, 1994, Volume: 85, Issue:3-4 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin	1994
A multinational study of the effects of low-dose pravastatin in patients with non-insulin-dependent diabetes mellitus and hypercholesterolemia. Pravastatin Multinational Study Group for Diabetes. Clinical cardiology, 1994, Volume: 17, Issue:10 Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycated Hemoglobin; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Triglycerides	1994
Efficacy and safety of pravastatin in the long-term treatment of elderly patients with hypercholesterolemia. The American journal of medicine, 1994, Volume: 96, Issue:6 Topics: Aged; Aged, 80 and over; Cholesterol; Double-Blind Method; Female; Humans; Hypercholesterolemia; Male; Pravastatin; Time Factors; Treatment Outcome; Triglycerides	1994
Associations of cholesterol lowering by statins with anger and hostility in hypercholesterolemic men. Biological psychiatry, 1994, Apr-15, Volume: 35, Issue:8 Topics: Adult; Aged; Anger; Cholesterol; Double-Blind Method; Hostility; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin	1994
[Effects of pravastatin administration for 12 months on serum lipid levels in aged patients with hypercholesterolemia]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1994, Volume: 31, Issue:4 Topics: Aged; Aged, 80 and over; Female; Humans; Hypercholesterolemia; Lipids; Long-Term Care; Male; Middle Aged; Pravastatin	1994
Efficacy and tolerability of simvastatin 20 mg vs pravastatin 20 mg in patients with primary hypercholesterolemia. European Study Group. Acta cardiologica, 1993, Volume: 48, Issue:6 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Tolerance; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Triglycerides	1993
Influence of cholesterol lowering on plasma membrane lipids and cationic transport systems. Journal of hypertension, 1994, Volume: 12, Issue:1 Topics: Biological Transport; Blood Platelets; Cations; Double-Blind Method; Erythrocyte Membrane; Female; Humans; Hypercholesterolemia; Male; Membrane Lipids; Middle Aged; Placebos; Pravastatin	1994
Plaque Hypertension Lipid-Lowering Italian Study (PHYLLIS): a protocol for non-invasive evaluation of carotid atherosclerosis in hypercholesterolaemic hypertensive subjects. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5 Topics: Aged; Arteriosclerosis; Carotid Artery Diseases; Clinical Protocols; Double-Blind Method; Female; Fosinopril; Humans; Hypercholesterolemia; Hypertension; Italy; Male; Middle Aged; Pravastatin; Ultrasonography	1993
[Pravastatin in patients with cardiac risk factors. Effects of pravastatin in patients with total serum cholesterol concentrations of 200 to 300 mg/dl (5.2 to 7.8 mmol/l) and two additional atherosclerosis risk factors. Pravastatin Multinational Study Gro Fortschritte der Medizin, 1994, Feb-20, Volume: 112, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Cholesterol; Coronary Artery Disease; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipids; Long-Term Care; Male; Middle Aged; Pravastatin; Risk Factors	1994
Comparison of effects on sleep of lovastatin and pravastatin in hypercholesterolemia. The American journal of cardiology, 1994, May-01, Volume: 73, Issue:12 Topics: Adult; Aged; Double-Blind Method; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Polysomnography; Pravastatin; Sleep	1994
[Pravastatin in the treatment of primary hypercholesterolemia: a Swiss multicenter study]. Schweizerische medizinische Wochenschrift, 1993, Sep-18, Volume: 123, Issue:37 Topics: Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Transaminases	1993
Effects of pravastatin in patients with serum total cholesterol levels from 5.2 to 7.8 mmol/liter (200 to 300 mg/dl) plus two additional atherosclerotic risk factors. The Pravastatin Multinational Study Group for Cardiac Risk Patients. The American journal of cardiology, 1993, Nov-01, Volume: 72, Issue:14 Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Cardiovascular Diseases; Double-Blind Method; Female; Humans; Hypercholesterolemia; Hypertension; Life Tables; Male; Middle Aged; Myocardial Infarction; Pravastatin; Risk Factors; Smoking; Treatment Outcome	1993
[Treatment of primary hypercholesterolemia with pravastatin. A placebo-controlled trial]. Ugeskrift for laeger, 1993, Sep-06, Volume: 155, Issue:36 Topics: Adult; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Placebos; Pravastatin	1993
Comparison of the lens opacities classification system II and Lensmeter 701. American journal of ophthalmology, 1993, Nov-15, Volume: 116, Issue:5 Topics: Adult; Arteriosclerosis; Cataract; Cholesterol, LDL; Humans; Hypercholesterolemia; Lens Cortex, Crystalline; Lens Nucleus, Crystalline; Male; Middle Aged; Ophthalmology; Photography; Pravastatin; Sensitivity and Specificity	1993
Treating hypercholesterolaemia with HMG CoA reductase inhibitors: a direct comparison of simvastatin and pravastatin. Australian and New Zealand journal of medicine, 1993, Volume: 23, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin	1993
Effects of pravastatin on apolipoprotein-specific high density lipoprotein subpopulations and low density lipoprotein subclass phenotypes in patients with primary hypercholesterolemia. Atherosclerosis, 1993, Volume: 102, Issue:1 Topics: Adult; Aged; Apolipoproteins; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Female; Glycoproteins; Humans; Hypercholesterolemia; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Phenotype; Pravastatin; Single-Blind Method	1993
[Pravastatin: efficacy and safety in elderly patients with primary hypercholesterolemia. Open multicenter study]. Arquivos brasileiros de cardiologia, 1993, Volume: 61, Issue:2 Topics: Aged; Cholesterol; Coronary Artery Disease; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Male; Pravastatin	1993
Efficacy and safety of pravastatin once daily in primary moderate hypercholesterolemia: the Israeli experience. Israel journal of medical sciences, 1993, Volume: 29, Issue:5 Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Creatine Kinase; Double-Blind Method; Female; Humans; Hypercholesterolemia; Israel; Liver Function Tests; Male; Middle Aged; Pravastatin; Risk Factors; Smoking; Triglycerides	1993
Treatment of primary hypercholesterolaemia. Short-term efficacy and safety of increasing doses of simvastatin and pravastatin: a double-blind comparative study. Journal of internal medicine, 1993, Volume: 234, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Treatment Outcome	1993
Effect of food on pravastatin pharmacokinetics and pharmacodynamics. International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:6 Topics: Cholesterol; Cholesterol, LDL; Food; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin; Time Factors	1993
[Cholesterol and vascular disease. Study of pravastatin ]. La Clinica terapeutica, 1993, Volume: 142, Issue:5 Topics: Adult; Aged; Cerebrovascular Disorders; Coronary Disease; Drug Evaluation; Female; Humans; Hypercholesterolemia; Lipoproteins, LDL; Male; Middle Aged; Pravastatin	1993
[Comparison of 2 cholesterol synthesis inhibitors (simvastatin and pravastatin)]. Schweizerische medizinische Wochenschrift, 1993, Aug-21, Volume: 123, Issue:33 Topics: Anticholesteremic Agents; Cholesterol; Humans; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin	1993
Combined therapy with probucol and pravastatin in hypercholesterolaemia. One year follow-up study. European journal of clinical pharmacology, 1993, Volume: 44, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Male; Middle Aged; Phospholipids; Pravastatin; Probucol; Triglycerides	1993
Long-term endocrine function in hypercholesterolemic patients treated with pravastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. Metabolism: clinical and experimental, 1993, Volume: 42, Issue:9 Topics: Adult; Aged; Aldosterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Double-Blind Method; Endocrine Glands; Female; Gonads; Humans; Hydrocortisone; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Placebos; Pravastatin; Prospective Studies; Time Factors	1993
Pravastatin and gemfibrozil alone and in combination for the treatment of hypercholesterolemia. The American journal of medicine, 1993, Volume: 94, Issue:1 Topics: Adult; Aged; Analysis of Variance; Apolipoproteins B; Cholesterol; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Single-Blind Method	1993
Effect of pravastatin on fatty acid profile of low density lipoprotein in patients with hypercholesterolemia. Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 48, Issue:2 Topics: Adult; Cholesterol; Cholesterol, LDL; Fatty Acids; Female; Humans; Hypercholesterolemia; Linoleic Acid; Linoleic Acids; Lipoproteins, LDL; Male; Middle Aged; Pravastatin	1993
A multicenter comparative trial of lovastatin and pravastatin in the treatment of hypercholesterolemia. The Lovastatin Pravastatin Study Group. The American journal of cardiology, 1993, Apr-01, Volume: 71, Issue:10 Topics: Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipoproteins; Liver Function Tests; Lovastatin; Male; Middle Aged; Pravastatin; Sleep	1993
Relative safety and efficacy of pravastatin. Clinical pharmacy, 1993, Volume: 12, Issue:4 Topics: Humans; Hypercholesterolemia; Lovastatin; Pravastatin	1993
Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study. Journal of clinical pharmacology, 1993, Volume: 33, Issue:3 Topics: Adult; Cholesterol; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Ubiquinone	1993
The effects of simvastatin and pravastatin on objective and subjective measures of nocturnal sleep: a comparison of two structurally different HMG CoA reductase inhibitors in patients with primary moderate hypercholesterolaemia. British journal of clinical pharmacology, 1993, Volume: 35, Issue:3 Topics: Adult; Aged; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Polysomnography; Pravastatin; Simvastatin; Sleep; Sleep Wake Disorders	1993
Comparative efficacy and safety of pravastatin and cholestyramine alone and combined in patients with hypercholesterolemia. Pravastatin Multicenter Study Group II. Archives of internal medicine, 1993, Jun-14, Volume: 153, Issue:11 Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Creatine Kinase; Double-Blind Method; Drug Combinations; Female; Humans; Hypercholesterolemia; Liver; Male; Middle Aged; Placebos; Pravastatin; Safety; Triglycerides	1993
Comparison of the efficacy, safety and tolerability of simvastatin and pravastatin for hypercholesterolemia. The Simvastatin Pravastatin Study Group. The American journal of cardiology, 1993, Jun-15, Volume: 71, Issue:16 Topics: Adult; Aged; Anticholesteremic Agents; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Sleep; Treatment Outcome	1993
The efficacy and safety of pravastatin in patients aged 60 to 85 years with low-density lipoprotein cholesterol > 160 mg/dl. The American journal of cardiology, 1996, Jan-01, Volume: 77, Issue:1 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Treatment Outcome	1996
The effectiveness and safety of low dose pravastatin in elderly hypertensive hypercholesterolemic subjects on antihypertensive therapy. American journal of hypertension, 1995, Volume: 8, Issue:11 Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Hypertension; Male; Patient Compliance; Placebos; Pravastatin	1995
[Comparison of pravastatin and diet in the treatment of hypercholesterolemia]. La Clinica terapeutica, 1995, Volume: 146, Issue:10 Topics: Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin	1995
Comparison of the effects on quality of life and of the efficacy and tolerability of lovastatin versus pravastatin. The Quality of Life Multicenter Group. The American journal of cardiology, 1996, Mar-01, Volume: 77, Issue:7 Topics: Adult; Anticholesteremic Agents; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Quality of Life; Treatment Outcome	1996
Cholesterol-lowering agent in men without CHD. The Journal of family practice, 1996, Volume: 42, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Coronary Disease; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Reproducibility of Results; Scotland; Survival Rate	1996
Lens opacity increase in a longitudinal study: comparison of the lens opacities classification system II and lensmeter 701. Current eye research, 1996, Volume: 15, Issue:3 Topics: Adult; Anticholesteremic Agents; Arteriosclerosis; Cataract; Evaluation Studies as Topic; Humans; Hypercholesterolemia; Lens, Crystalline; Longitudinal Studies; Male; Middle Aged; Ophthalmology; Pravastatin; Prospective Studies; Sensitivity and Specificity	1996
Fluvastatin versus pravastatin. The American journal of cardiology, 1996, Jul-01, Volume: 78, Issue:1 Topics: Anticholesteremic Agents; Drug Administration Schedule; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Pravastatin	1996
Effectiveness and safety of low-dose pravastatin and squalene, alone and in combination, in elderly patients with hypercholesterolemia. Journal of clinical pharmacology, 1996, Volume: 36, Issue:5 Topics: Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Male; Placebos; Pravastatin; Squalene; Triglycerides	1996
Influence of cholesterol-lowering on plasma membrane lipids and function. Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:2 Topics: Acyl Coenzyme A; Adult; Anticholesteremic Agents; Apolipoproteins; Blood Platelets; Cell Membrane; Cholesterol; Double-Blind Method; Enzyme Inhibitors; Erythrocytes; Female; Humans; Hypercholesterolemia; Male; Membrane Lipids; Phosphatidylcholine-Sterol O-Acyltransferase; Phospholipids; Pravastatin; Sodium-Potassium-Exchanging ATPase; Triglycerides	1996
Effects of pravastatin in heart transplant recipients: implications of Kobashigawa et al. Current opinion in lipidology, 1995, Volume: 6, Issue:6 Topics: Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Coronary Vessels; Cytotoxicity, Immunologic; Female; Graft Rejection; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunosuppressive Agents; Killer Cells, Natural; Male; Pravastatin; Prospective Studies	1995
[Victory in primary prevention--or? Can we afford to translate results from the West-of-Scotland Study into general practice?]. Fortschritte der Medizin, 1996, Jun-20, Volume: 114, Issue:17 Topics: Anticholesteremic Agents; Cholesterol; Coronary Disease; Cost-Benefit Analysis; Germany; Humans; Hypercholesterolemia; Male; Myocardial Infarction; Pravastatin; Scotland	1996
Increased oxidation resistance of atherogenic plasma lipoproteins at high vitamin E levels in non-vitamin E supplemented men. Atherosclerosis, 1996, Volume: 124, Issue:1 Topics: Adult; Anticholesteremic Agents; Antioxidants; Arteriosclerosis; Ascorbic Acid; beta Carotene; Cholesterol, LDL; Copper; Dietary Fats; Double-Blind Method; Humans; Hypercholesterolemia; Linoleic Acid; Linoleic Acids; Lipids; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Oxidation-Reduction; Pravastatin; Risk Factors; Smoking; Vitamin E	1996
Pravastatin and risk factor modification in patients with moderate primary hypercholesterolaemia. The New Zealand medical journal, 1996, Aug-23, Volume: 109, Issue:1028 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Exercise Therapy; Feeding Behavior; Female; Humans; Hypercholesterolemia; Life Style; Male; Middle Aged; Placebos; Pravastatin; Risk Factors; Smoking Cessation; Triglycerides	1996
Effects of hypercholesterolemia of renal hemodynamics: study in patients with nephrotic syndrome. Nephron, 1996, Volume: 73, Issue:3 Topics: Adult; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Inulin; Kidney Function Tests; Male; Middle Aged; Nephrotic Syndrome; p-Aminohippuric Acid; Pravastatin; Proteinuria; Renal Circulation; Single-Blind Method	1996
Beneficial effects of pravastatin on fasting hyperinsulinemia in elderly hypertensive hypercholesterolemic subjects. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:4 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol, HDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Hyperinsulinism; Hypertension; Male; Patient Compliance; Pravastatin; Prospective Studies	1996
Cholesterol lowering therapy inhibits the low-flow mediated vasoconstriction of the brachial artery in hypercholesterolaemic subjects. British journal of clinical pharmacology, 1996, Volume: 42, Issue:2 Topics: Adult; Anticholesteremic Agents; Brachial Artery; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Vasoconstriction	1996
Effects of inhibiting cholesterol absorption and synthesis on cholesterol and lipoprotein metabolism in hypercholesterolemic non-insulin-dependent diabetic men. Journal of lipid research, 1996, Volume: 37, Issue:8 Topics: Absorption; Anticholesteremic Agents; Blood Specimen Collection; Cholesterol; Diabetes Mellitus, Type 2; Double-Blind Method; Humans; Hypercholesterolemia; Lipoproteins; Male; Middle Aged; Patient Selection; Pravastatin; Sitosterols; Triglycerides	1996
Insoluble complex formation between LDL and arterial proteoglycans in relation to serum lipid levels and effects of lipid lowering drugs. Atherosclerosis, 1996, Jan-05, Volume: 119, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Arteries; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Proteoglycans	1996
Decision rules for predicting future lipid values in screening for a cholesterol reduction clinical trial. Controlled clinical trials, 1996, Volume: 17, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Cost Control; Decision Support Techniques; Female; Humans; Hypercholesterolemia; Male; Mass Screening; Middle Aged; Multivariate Analysis; Normal Distribution; Patient Selection; Pravastatin; Randomized Controlled Trials as Topic; Sensitivity and Specificity	1996
[Congress information. Clinical benefits of the use of a statin following myocardial infarction in patients without frank hypercholesterolemia]. Revue medicale de Liege, 1996, Volume: 51, Issue:10 Topics: Adult; Aged; Anticholesteremic Agents; Double-Blind Method; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin	1996
Pravastatin reduces carotid intima-media thickness progression in an asymptomatic hypercholesterolemic mediterranean population: the Carotid Atherosclerosis Italian Ultrasound Study. The American journal of medicine, 1996, Volume: 101, Issue:6 Topics: Anticholesteremic Agents; Carotid Stenosis; Disease Progression; Double-Blind Method; Female; Humans; Hypercholesterolemia; Italy; Lipids; Male; Middle Aged; Pravastatin; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography	1996
Baseline risk factors and their association with outcome in the West of Scotland Coronary Prevention Study. The West of Scotland Coronary Prevention Study Group. The American journal of cardiology, 1997, Mar-15, Volume: 79, Issue:6 Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Pravastatin; Probability; Risk Factors; Scotland; Time Factors; Treatment Outcome	1997
Effect of pravastatin in treatment of hypercholesterolemia in non-insulin-dependent diabetes patients. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1997, Volume: 80, Issue:1 Topics: Aged; Anticholesteremic Agents; Diabetes Mellitus, Type 2; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies; Treatment Outcome	1997
[Comparative effects of captopril and atenolol on lipid metabolism in hypertensive hypercholesterolemic patients treated with pravastatin. A multicenter controlled trial]. Presse medicale (Paris, France : 1983), 1996, Dec-21, Volume: 25, Issue:40 Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Atenolol; Captopril; Double-Blind Method; Female; Humans; Hypercholesterolemia; Hypertension; Lipid Metabolism; Male; Middle Aged; Pravastatin; Time Factors	1996
[Long term treatment of moderate to severe hypercholesterolemia with low dose statin. Comparison of simvastatin and pravastatin]. Recenti progressi in medicina, 1996, Volume: 87, Issue:11 Topics: Aged; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pravastatin; Severity of Illness Index; Simvastatin; Time Factors	1996
Efficacy and safety of atorvastatin compared to pravastatin in patients with hypercholesterolemia. Atherosclerosis, 1997, Volume: 130, Issue:1-2 Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol; Cholesterol, LDL; Double-Blind Method; Enzyme Inhibitors; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Pyrroles; Triglycerides	1997
A comparison of estrogen replacement, pravastatin, and combined treatment for the management of hypercholesterolemia in postmenopausal women. Archives of internal medicine, 1997, Jun-09, Volume: 157, Issue:11 Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Diet, Fat-Restricted; Double-Blind Method; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Hypercholesterolemia; Middle Aged; Postmenopause; Pravastatin; Time Factors; Triglycerides	1997
Combination of low-dose niacin and pravastatin improves the lipid profile in diabetic patients without compromising glycemic control. The Annals of pharmacotherapy, 1997, Volume: 31, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Blood Glucose; Cholesterol, LDL; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Inhibitors; Female; Fructosamine; Humans; Hypercholesterolemia; Lipoprotein(a); Male; Middle Aged; Niacin; Pravastatin; Prospective Studies	1997
A coronary primary intervention study of Japanese men: study design, implementation and baseline data. The Kyushu Lipid Intervention Study Group. Journal of atherosclerosis and thrombosis, 1996, Volume: 3, Issue:2 Topics: Aged; Anticholesteremic Agents; Clinical Protocols; Coronary Disease; Follow-Up Studies; Humans; Hypercholesterolemia; Japan; Male; Middle Aged; Pravastatin; Primary Prevention; Prospective Studies; Random Allocation; Statistics as Topic	1996
Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. Molecular aspects of medicine, 1997, Volume: 18 Suppl Topics: Adult; Aged; Antioxidants; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Coenzymes; Coronary Disease; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Oxidation-Reduction; Pravastatin; Risk Factors; Ubiquinone	1997
Crossover trial of simvastatin versus pravastatin in patients with primary hypercholesterolemia. Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Cross-Over Studies; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin	1997
Pravastatin alone and in combination with low-dose cholestyramine in patients with primary hypercholesterolemia and coronary artery disease. The American journal of cardiology, 1997, Sep-15, Volume: 80, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Coronary Disease; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Triglycerides	1997
[Pravastatin multicenter clinical trial in patients with hypercholesterolemia and multiple risk factors]. Arquivos brasileiros de cardiologia, 1997, Volume: 68, Issue:1 Topics: Adolescent; Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Diabetes Complications; Female; Humans; Hypercholesterolemia; Hypertension; Male; Menopause; Middle Aged; Obesity; Pravastatin; Risk Factors; Sex Factors; Smoking	1997
Modulation of lipoprotein(a) atherogenicity by high density lipoprotein cholesterol levels in middle-aged men with symptomatic coronary artery disease and normal to moderately elevated serum cholesterol. Regression Growth Evaluation Statin Study (REGRESS) Journal of the American College of Cardiology, 1997, Nov-15, Volume: 30, Issue:6 Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Coronary Angiography; Coronary Artery Disease; Disease Progression; Double-Blind Method; Humans; Hypercholesterolemia; Lipoprotein(a); Male; Middle Aged; Multivariate Analysis; Pravastatin; Prospective Studies; Reference Values	1997
The hypertensive patient with multiple risk factors: is treatment really so difficult? American journal of hypertension, 1997, Volume: 10, Issue:10 Pt 2 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticholesteremic Agents; Antihypertensive Agents; Arteriosclerosis; Clinical Trials as Topic; Coronary Disease; Female; Fosinopril; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Pravastatin; Risk Factors	1997
The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. The Regression Growth Evaluation Statin Study Group. The New England journal of medicine, 1998, Jan-08, Volume: 338, Issue:2 Topics: Anticholesteremic Agents; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Cholesterol, HDL; Coronary Artery Disease; Disease Progression; Dose-Response Relationship, Drug; Glycoproteins; Humans; Hypercholesterolemia; Male; Middle Aged; Polymorphism, Genetic; Pravastatin; Prospective Studies	1998
The West of Scotland coronary prevention study: economic benefit analysis of primary prevention with pravastatin. BMJ (Clinical research ed.), 1997, Dec-13, Volume: 315, Issue:7122 Topics: Anticholesteremic Agents; Coronary Disease; Cost-Benefit Analysis; Drug Costs; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Pravastatin; Scotland; Sensitivity and Specificity; Treatment Outcome	1997
Pravastatin in diabetes-associated hypercholesterolemia. Acta diabetologica, 1997, Volume: 34, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Hypercholesterolemia; Lipid Metabolism; Lipids; Male; Middle Aged; Pravastatin; Time Factors	1997
Short-term treatment with low-dose pravastatin attenuates oxidative susceptibility of low-density lipoprotein in hypercholesterolemic patients. Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:6 Topics: Adult; Female; Glutathione; Humans; Hypercholesterolemia; Hypolipidemic Agents; Kinetics; Lipids; Lipoproteins, LDL; Male; Oxidation-Reduction; Phenotype; Pravastatin; Thiobarbituric Acid Reactive Substances; Vitamin E	1997
Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study) The American journal of cardiology, 1998, Mar-01, Volume: 81, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Treatment Outcome	1998
Effects of extensive and poor gastrointestinal metabolism on the pharmacodynamics of pravastatin. Journal of clinical pharmacology, 1998, Volume: 38, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Biological Availability; Cholesterol, LDL; Digestive System; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies	1998
Efficacy and safety of a new cholesterol synthesis inhibitor, atorvastatin, in comparison with simvastatin and pravastatin, in subjects with hypercholesterolemia. The Netherlands journal of medicine, 1998, Volume: 52, Issue:4 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Atorvastatin; Cholesterol; Cholesterol, LDL; Cross-Over Studies; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Treatment Outcome; Triglycerides	1998
Effects of long-term pravastatin treatment on spermatogenesis and on adrenal and testicular steroidogenesis in male hypercholesterolemic patients. Journal of endocrinological investigation, 1998, Volume: 21, Issue:5 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotropin; Corticotropin-Releasing Hormone; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged; Pravastatin; Spermatogenesis; Steroids; Testis; Time Factors	1998
Compliance with and efficacy of treatment with pravastatin and cholestyramine: a randomized study on lipid-lowering in primary care. Journal of internal medicine, 1998, Volume: 243, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Patient Compliance; Pravastatin; Primary Health Care; Sex Factors; Sweden; Treatment Outcome	1998
Effects of vitamin E and HMG-CoA reductase inhibition on cholesteryl ester transfer protein and lecithin-cholesterol acyltransferase in hypercholesterolemia. Coronary artery disease, 1998, Volume: 9, Issue:5 Topics: Antioxidants; Carrier Proteins; Cholesterol Ester Transfer Proteins; Combined Modality Therapy; Drug Therapy, Combination; Female; Glycoproteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Phosphatidylcholine-Sterol O-Acyltransferase; Pravastatin; Vitamin E	1998
Clinical efficacy and safety of cerivastatin: summary of pivotal phase IIb/III studies. The American journal of cardiology, 1998, Aug-27, Volume: 82, Issue:4B Topics: Adolescent; Adult; Aged; Apolipoprotein A-I; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Pyridines; Safety; Simvastatin; Treatment Outcome	1998
Diet and pravastatin in moderate hypercholesterolaemia: a randomized trial in 215 middle-aged men free from cardiovascular disease. Journal of internal medicine, 1998, Volume: 244, Issue:5 Topics: Anticholesteremic Agents; Blood Pressure; Body Weight; Combined Modality Therapy; Double-Blind Method; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Patient Compliance; Pravastatin; Treatment Outcome	1998
Cholesteryl ester transfer in hypercholesterolaemia: fasting and postprandial studies with and without pravastatin. Atherosclerosis, 1998, Volume: 141, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Carrier Proteins; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Cholesterol, LDL; Cross-Over Studies; Dietary Fats; Double-Blind Method; Fasting; Female; Glycoproteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins, VLDL; Male; Middle Aged; Postprandial Period; Pravastatin; Triglycerides	1998
Influence of baseline lipids on effectiveness of pravastatin in the CARE Trial. Cholesterol And Recurrent Events. Journal of the American College of Cardiology, 1999, Volume: 33, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Cohort Studies; Female; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Myocardial Infarction; Pravastatin; Recurrence; Survival Rate; Treatment Outcome; Triglycerides	1999
Comparison of the effects of pravastatin and lovastatin on sleep disturbance in hypercholesterolemic subjects. Sleep, 1999, Feb-01, Volume: 22, Issue:1 Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Sleep Wake Disorders; Sleep, REM	1999
Clinical trials in stroke. Lancet (London, England), 1999, Jan-09, Volume: 353, Issue:9147 Topics: Cerebrovascular Disorders; Double-Blind Method; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Risk; Treatment Outcome	1999
Comparative efficacy and tolerability of low-dose pravastatin versus lovastatin in patients with hypercholesterolemia. American heart journal, 1999, Volume: 137, Issue:3 Topics: Aged; Alkaline Phosphatase; Anticholesteremic Agents; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatine Kinase; Cross-Over Studies; Drug Costs; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; L-Lactate Dehydrogenase; Liver; Lovastatin; Male; Middle Aged; Pravastatin; Triglycerides	1999
[Clinical study of the month. The LIPID study: "long-term intervention with pravastatin in ischaemic disease"]. Revue medicale de Liege, 1999, Volume: 54, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Coronary Disease; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin	1999
The effects of pravastatin on hospital admission in hypercholesterolemic middle-aged men: West of Scotland Coronary Prevention Study. Journal of the American College of Cardiology, 1999, Mar-15, Volume: 33, Issue:4 Topics: Anticholesteremic Agents; Coronary Disease; Follow-Up Studies; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Patient Admission; Pravastatin; Primary Health Care; Prospective Studies; Scotland	1999
Effects of cholesterol-lowering treatments on oxidative modification of plasma intermediate density lipoprotein plus low density lipoprotein fraction in Type 2 diabetic patients. Diabetes research and clinical practice, 1999, Volume: 43, Issue:2 Topics: Anticholesteremic Agents; Apolipoproteins B; Blood Glucose; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Humans; Hypercholesterolemia; Lipid Peroxidation; Lipid Peroxides; Lipoproteins; Lipoproteins, IDL; Lipoproteins, LDL; Male; Middle Aged; Phospholipids; Pravastatin; Probucol; Regression Analysis; Smoking; Time Factors; Triglycerides	1999
Additional reduction in blood pressure after cholesterol-lowering treatment by statins (lovastatin or pravastatin) in hypercholesterolemic patients using angiotensin-converting enzyme inhibitors (enalapril or lisinopril). The American journal of cardiology, 1999, May-15, Volume: 83, Issue:10 Topics: Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Blood Pressure; Drug Interactions; Enalapril; Female; Heart Rate; Humans; Hypercholesterolemia; Hypertension; Lisinopril; Lovastatin; Male; Middle Aged; Pravastatin	1999
Effect of treatment with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on serum coenzyme Q10 in diabetic patients. Arzneimittel-Forschung, 1999, Volume: 49, Issue:4 Topics: Adult; Anticholesteremic Agents; Antioxidants; Cholesterol; Chromatography, High Pressure Liquid; Coenzymes; Diabetes Mellitus, Type 2; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Simvastatin; Ubiquinone	1999
Effect of pravastatin on erythrocyte rheological and biochemical properties in poorly controlled Type 2 diabetic patients. Diabetic medicine : a journal of the British Diabetic Association, 1999, Volume: 16, Issue:5 Topics: Anticholesteremic Agents; Blood Pressure; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Double-Blind Method; Electrolytes; Erythrocyte Deformability; Erythrocyte Membrane; Erythrocytes; Female; Fructosamine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Phospholipids; Placebos; Pravastatin; Reference Values; Rheology	1999
Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes. The RECIFE (reduction of cholesterol in ischemia and function of the endothelium) trial. Circulation, 1999, Jun-29, Volume: 99, Issue:25 Topics: Anticholesteremic Agents; Blood Pressure; Brachial Artery; Cholesterol; Confounding Factors, Epidemiologic; Coronary Disease; Double-Blind Method; Endothelins; Endothelium, Vascular; Female; Heart Rate; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin; Stroke Volume; Syndrome; Ultrasonography; Vasodilation	1999
Treatment of hypertensive and hypercholesterolaemic patients in general practice. The effect of captopril, atenolol and pravastatin combined with life style intervention. Scandinavian journal of primary health care, 1999, Volume: 17, Issue:2 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Atenolol; Captopril; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hypertension; Life Style; Male; Middle Aged; Norway; Pravastatin; Statistics, Nonparametric	1999
Overlap analysis of the West of Scotland coronary prevention study (WOSCOPS). Circulation, 1999, Aug-10, Volume: 100, Issue:6 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Research Design; Risk Factors; Scotland	1999
Effect of plasma cholesterol reduction by pravastatin on the functional properties of forearm arteries in hypercholesterolemic patients. Nutrition, metabolism, and cardiovascular diseases : NMCD, 1999, Volume: 9, Issue:3 Topics: Acetylcholine; Adult; Analysis of Variance; Anticholesteremic Agents; Area Under Curve; Blood Component Removal; Brachial Artery; Cholesterol, LDL; Female; Forearm; Hemodynamics; Humans; Hypercholesterolemia; Male; Middle Aged; Nitroglycerin; Plethysmography; Pravastatin; Vascular Resistance; Vasodilator Agents	1999
Lowering effects of four different statins on serum triglyceride level. European journal of clinical pharmacology, 1999, Volume: 55, Issue:7 Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hypercholesterolemia; Indoles; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Treatment Outcome; Triglycerides	1999
[Short- and long-term effects of intensified versus conventional antilipidemic therapy in patients with coronary heart disease. Results from the Lipid-Coronary Artery Disease (L-CAD) Study]. Zeitschrift fur Kardiologie, 1999, Volume: 88, Issue:8 Topics: Adult; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Cholesterol, LDL; Cholestyramine Resin; Coronary Disease; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Niacin; Pravastatin; Prospective Studies; Treatment Outcome	1999
Double-masked comparison of the quality of life of hypercholesterolemic men treated with simvastatin or pravastatin. International Quality of Life Multicenter Group. Clinical therapeutics, 1999, Volume: 21, Issue:10 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Quality of Life; Sexual Behavior; Simvastatin	1999
Effect of the HMG-CoA reductase inhibitors on blood pressure in patients with essential hypertension and primary hypercholesterolemia. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:6 Topics: Adult; Aged; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cold Temperature; Cross-Over Studies; Double-Blind Method; Endothelins; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Middle Aged; Pravastatin; Treatment Outcome	1999
Effects of simvastatin and pravastatin on gonadal function in male hypercholesterolemic patients. Metabolism: clinical and experimental, 2000, Volume: 49, Issue:1 Topics: Adult; Cholesterol; Cholesterol, LDL; Gonadal Steroid Hormones; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Simvastatin; Spermatogenesis; Spermatozoa; Testis; Testosterone; Triglycerides	2000
Benefits of lipid lowering on vascular reactivity in patients with coronary artery disease and average cholesterol levels: a mechanism for reducing clinical events? American heart journal, 2000, Volume: 139, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Pravastatin; Recurrence; Triglycerides; Vasodilation	2000
Use of statins and blood pressure control in treated hypertensive patients with hypercholesterolemia. Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Pravastatin; Simvastatin	2000
Pravastatin: an antithrombotic effect independent of the cholesterol-lowering effect. Thrombosis and haemostasis, 2000, Volume: 83, Issue:5 Topics: Aged; Anticholesteremic Agents; Blood Coagulation; Cholesterol, LDL; Double-Blind Method; Female; Fibrinolysis; Fibrinolytic Agents; Hemorheology; Humans; Hypercholesterolemia; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Pravastatin; Prospective Studies; Risk Factors; Tissue Plasminogen Activator	2000
Incremental reduction of serum total cholesterol and low-density lipoprotein cholesterol with the addition of plant stanol ester-containing spread to statin therapy. The American journal of cardiology, 2000, Jul-01, Volume: 86, Issue:1 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Atorvastatin; Biomarkers; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Male; Margarine; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Sitosterols; Treatment Outcome; Triglycerides	2000
Effects of policosanol and pravastatin on lipid profile, platelet aggregation and endothelemia in older hypercholesterolemic patients. International journal of clinical pharmacology research, 1999, Volume: 19, Issue:4 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Double-Blind Method; Endothelium, Vascular; Fatty Alcohols; Female; Humans; Hypercholesterolemia; Lipid Metabolism; Male; Middle Aged; Platelet Aggregation; Pravastatin; Treatment Outcome	1999
Efficacy and safety of cerivastatin and pravastatin in the treatment of primary hypercholesterolemia. Journal of the National Medical Association, 2000, Volume: 92, Issue:7 Topics: Adolescent; Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Pyridines; Safety; Stereoisomerism; Treatment Outcome; Triglycerides	2000
Rationale, design, and baseline characteristics of a trial of prevention of cardiovascular and renal disease with fosinopril and pravastatin in nonhypertensive, nonhypercholesterolemic subjects with microalbuminuria (the Prevention of REnal and Vascular E The American journal of cardiology, 2000, Sep-15, Volume: 86, Issue:6 Topics: Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Female; Fosinopril; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Diseases; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Research Design	2000
Statins and cardiovascular diseases: the multiple effects of lipid-lowering therapy by statins. Atherosclerosis, 2000, Volume: 153, Issue:1 Topics: Anticholesteremic Agents; Blood Coagulation; Cardiovascular Diseases; Cell Adhesion Molecules; Endothelium, Vascular; Humans; Hypercholesterolemia; Middle Aged; Pravastatin; Simvastatin; Solubility; Vasomotor System	2000
Long-term assessment of psychological well-being in a randomized placebo-controlled trial of cholesterol reduction with pravastatin. The LIPID Study Investigators. Archives of internal medicine, 2000, Nov-13, Volume: 160, Issue:20 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Double-Blind Method; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Time Factors	2000
Randomized comparison of the efficacy and safety of cerivastatin and pravastatin in 1,030 hypercholesterolemic patients. The Cerivastatin Study Group. Mayo Clinic proceedings, 2000, Volume: 75, Issue:11 Topics: Adolescent; Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged; Pravastatin; Prospective Studies; Pyridines; Treatment Outcome; Triglycerides	2000
Operational aspects of terminating the doxazosin arm of The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Controlled clinical trials, 2001, Volume: 22, Issue:1 Topics: Adverse Drug Reaction Reporting Systems; Antihypertensive Agents; Cause of Death; Coronary Disease; Databases, Factual; Double-Blind Method; Doxazosin; Female; Heart Failure; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Myocardial Infarction; Pravastatin; Risk Assessment; Survival Rate; Treatment Outcome; United States	2001
Systolic and pulse blood pressures (but not diastolic blood pressure and serum cholesterol) are associated with alterations in carotid intima-media thickness in the moderately hypercholesterolaemic hypertensive patients of the Plaque Hypertension Lipid Lo Journal of hypertension, 2001, Volume: 19, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carotid Arteries; Cholesterol; Disease Progression; Drug Therapy, Combination; Female; Fosinopril; Heart Rate; Humans; Hypercholesterolemia; Hypertension; Italy; Male; Middle Aged; Pravastatin; Systole; Tunica Intima; Ultrasonography	2001
Similar effects of atorvastatin, simvastatin and pravastatin on thrombogenic and inflammatory parameters in patients with hypercholesterolemia. Thrombosis and haemostasis, 2001, Volume: 85, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation; Lipids; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Therapeutic Equivalency; Thrombophilia; Treatment Outcome	2001
Comparative efficacy study of atorvastatin vs simvastatin, pravastatin, lovastatin and placebo in type 2 diabetic patients with hypercholesterolaemia. Diabetes, obesity & metabolism, 2000, Volume: 2, Issue:6 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin; Lovastatin; Male; Middle Aged; Placebos; Pravastatin; Pyrroles; Simvastatin; Triglycerides	2000
Statin therapy and plasma C-reactive protein levels in primary prevention. Cardiovascular drugs and therapy, 2000, Volume: 14, Issue:6 Topics: Aged; Anticholesteremic Agents; Arteriosclerosis; Biomarkers; C-Reactive Protein; Cholesterol; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin	2000
Baseline characteristics of the diabetic participants in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Diabetes care, 2001, Volume: 24, Issue:4 Topics: Adrenergic alpha-Antagonists; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cholesterol, Dietary; Cohort Studies; Coronary Disease; Double-Blind Method; Doxazosin; Ethnicity; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Pravastatin; Racial Groups; Risk Factors; United States	2001
Aggressive versus moderate lipid-lowering therapy in postmenopausal women with hypercholesterolemia: Rationale and design of the Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES) trial. American heart journal, 2001, Volume: 141, Issue:5 Topics: Aged; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Cholesterol, LDL; Coronary Vessels; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Middle Aged; Postmenopause; Pravastatin; Prognosis; Prospective Studies; Pyrroles; Reproducibility of Results; Safety; Tomography, X-Ray Computed	2001
Cost-effectiveness of pravastatin therapy for survivors of myocardial infarction with average cholesterol levels. American heart journal, 2001, Volume: 141, Issue:5 Topics: Anticholesteremic Agents; Cholesterol, LDL; Cost-Benefit Analysis; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Pravastatin; Quality of Life; Secondary Prevention; Sensitivity and Specificity; Survival Rate; United States	2001
Effects of 1-year treatment with fluvastatin or pravastatin on bone. The American journal of medicine, 2001, Volume: 110, Issue:7 Topics: Aged; Anticholesteremic Agents; Bone and Bones; Bone Density; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Postmenopause; Pravastatin	2001
Benefits of pravastatin on cardiovascular events and mortality in older patients with coronary heart disease are equal to or exceed those seen in younger patients: Results from the LIPID trial. Annals of internal medicine, 2001, May-15, Volume: 134, Issue:10 Topics: Adult; Aged; Anticholesteremic Agents; Cause of Death; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies; Risk Factors	2001
Summaries for patients. Benefits of lowering cholesterol levels in older patients. Annals of internal medicine, 2001, May-15, Volume: 134, Issue:10 Topics: Adult; Aged; Anticholesteremic Agents; Cause of Death; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies; Risk Factors	2001
Pravastatin therapy increases procollagen I N-terminal propeptide (PINP), a marker of bone formation in post-menopausal women. Clinica chimica acta; international journal of clinical chemistry, 2001, Volume: 308, Issue:1-2 Topics: Adult; Alkaline Phosphatase; Biomarkers; Bone Regeneration; Cholesterol; Female; Humans; Hypercholesterolemia; Middle Aged; Peptide Fragments; Postmenopause; Pravastatin; Procollagen	2001
Influence of pravastatin on lipoproteins, and on endothelial, platelet, and inflammatory markers in subjects with peripheral artery disease. The American journal of cardiology, 2001, Jul-01, Volume: 88, Issue:1 Topics: Aged; Anticholesteremic Agents; C-Reactive Protein; Case-Control Studies; Double-Blind Method; Female; Humans; Hypercholesterolemia; Intercellular Adhesion Molecule-1; Lipids; Male; Middle Aged; P-Selectin; Peripheral Vascular Diseases; Pravastatin; Statistics, Nonparametric; von Willebrand Factor	2001
Pravastatin use and risk of coronary events and cerebral infarction in japanese men with moderate hypercholesterolemia: the Kyushu Lipid Intervention Study. Journal of atherosclerosis and thrombosis, 2000, Volume: 7, Issue:2 Topics: Aged; Anticholesteremic Agents; Cerebral Infarction; Coronary Disease; Follow-Up Studies; Humans; Hypercholesterolemia; Japan; Lipids; Male; Middle Aged; Neoplasms; Patient Compliance; Pravastatin; Risk Factors	2000
Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases. The American journal of cardiology, 2001, Jul-15, Volume: 88, Issue:2 Topics: Adult; Anticholesteremic Agents; Double-Blind Method; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Matrix Metalloproteinase 9; Polymorphism, Genetic; Pravastatin	2001
Reduced levels of TNF alpha in hypercholesterolemic individuals after treatment with pravastatin for 8 weeks. Atherosclerosis, 2001, Volume: 157, Issue:2 Topics: Anticholesteremic Agents; Biomarkers; Double-Blind Method; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin; Time Factors; Tumor Necrosis Factor-alpha	2001
Dietary advice with or without pravastatin for the management of hypercholesterolaemia associated with protease inhibitor therapy. AIDS (London, England), 2001, Aug-17, Volume: 15, Issue:12 Topics: Anticholesteremic Agents; Cholesterol, LDL; Combined Modality Therapy; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hypercholesterolemia; Male; Pravastatin; Viral Load	2001
Effects of lovastatin and pravastatin on cognitive function in military aircrew. Aviation, space, and environmental medicine, 2001, Volume: 72, Issue:9 Topics: Adult; Anticholesteremic Agents; Cognition; Double-Blind Method; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Military Personnel; Neuropsychological Tests; Pravastatin; Psychomotor Performance	2001
Effect of lipid-lowering therapy with pravastatin on myocardial blood flow in young mildly hypercholesterolemic adults. Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:4 Topics: Adult; Age Factors; Analysis of Variance; Anticholesteremic Agents; Coronary Circulation; Double-Blind Method; Humans; Hypercholesterolemia; Lipids; Male; Pravastatin; Tomography, Emission-Computed	2001
Cerivastatin versus branded pravastatin in the treatment of primary hypercholesterolemia in primary care practice in Canada: a one-year, open-label, randomized, comparative study of efficacy, safety, and cost-effectiveness. Clinical therapeutics, 2001, Volume: 23, Issue:9 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Female; Health Care Costs; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Pyridines; Treatment Outcome	2001
Long-term efficacy and safety of cerivastatin 0.8 mg in patients with primary hypercholesterolemia. Clinical cardiology, 2001, Volume: 24, Issue:9 Suppl Topics: Adolescent; Aged; Anticholesteremic Agents; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies; Pyridines	2001
Cholesterol lowering with statins reduces exercise-induced myocardial ischemia in hypercholesterolemic patients with coronary artery disease. The American journal of cardiology, 2001, Nov-15, Volume: 88, Issue:10 Topics: Adult; Aged; Anticholesteremic Agents; Coronary Angiography; Coronary Disease; Exercise Test; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Ischemia; Pravastatin; Simvastatin	2001
Estrogen/progesterone replacement versus pravastatin and their sequential association in hypercholesterolemic postmenopausal women. Maturitas, 2001, Dec-14, Volume: 40, Issue:3 Topics: Administration, Oral; Anticholesteremic Agents; Apolipoproteins; Cholesterol, HDL; Cholesterol, LDL; Diet; Estrogens, Conjugated (USP); Exercise; Female; Hormone Replacement Therapy; Humans; Hypercholesterolemia; Middle Aged; Postmenopause; Pravastatin; Progesterone; Treatment Outcome; Triglycerides	2001
The effects of lipid-lowering and antioxidant vitamin therapies on flow-mediated vasodilation of the brachial artery in older adults with hypercholesterolemia. Journal of the American College of Cardiology, 2001, Volume: 38, Issue:7 Topics: Aged; Aged, 80 and over; Ascorbic Acid; Brachial Artery; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Hypercholesterolemia; Long-Term Care; Male; Pravastatin; Simvastatin; Vasodilation; Vitamin A	2001
Hypercholesterolaemia and lipid lowering treatment do not affect the acute endogenous fibrinolytic capacity in vivo. Heart (British Cardiac Society), 2002, Volume: 87, Issue:1 Topics: Adult; Anticholesteremic Agents; Blood Flow Velocity; Blood Pressure; Case-Control Studies; Cross-Over Studies; Double-Blind Method; Female; Fibrinolysis; Forearm; Humans; Hypercholesterolemia; Male; Pravastatin; Substance P; Tissue Plasminogen Activator	2002
Effect of pravastatin on responsiveness to N-monomethyl-L-arginine in patients with hypercholesterolaemia. Atherosclerosis, 2002, Volume: 160, Issue:1 Topics: Australia; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Kidney; Male; Middle Aged; omega-N-Methylarginine; Pravastatin; Time Factors; Triglycerides	2002
A comparison of low versus standard dose pravastatin therapy for the prevention of cardiovascular events in the elderly: the pravastatin anti-atherosclerosis trial in the elderly (PATE). Journal of atherosclerosis and thrombosis, 2001, Volume: 8, Issue:2 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Arteriosclerosis; Cardiovascular Diseases; Cholesterol; Diabetes Complications; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies; Risk Factors; Safety; Triglycerides	2001
[Effect of hypolipemic agents on levels of total plasma homocysteine]. Vnitrni lekarstvi, 2001, Volume: 47, Issue:10 Topics: Adolescent; Adult; Aged; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Middle Aged; Pravastatin; Vitamin B 12; Vitamin B 6	2001
Maintenance of low-density lipoprotein goal with step-down pravastatin therapy. Pharmacotherapy, 2002, Volume: 22, Issue:1 Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies; Treatment Outcome	2002
A comparison of continuous combined hormone replacement therapy, HMG-CoA reductase inhibitor and combined treatment for the management of hypercholesterolemia in postmenopausal women. The journal of obstetrics and gynaecology research, 2001, Volume: 27, Issue:6 Topics: Anticholesteremic Agents; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Administration Schedule; Drug Therapy, Combination; Female; Hormone Replacement Therapy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Middle Aged; Postmenopause; Pravastatin; Prospective Studies; Triglycerides	2001
Lipid-lowering therapy with fluvastatin inhibits oxidative modification of low density lipoprotein and improves vascular endothelial function in hypercholesterolemic patients. Atherosclerosis, 2002, Volume: 160, Issue:2 Topics: Endothelium, Vascular; Fatty Acids, Monounsaturated; Female; Fluvastatin; Forearm; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Pravastatin; Prospective Studies; Vasodilation	2002
Effects of probucol and pravastatin on common carotid atherosclerosis in patients with asymptomatic hypercholesterolemia. Fukuoka Atherosclerosis Trial (FAST). Journal of the American College of Cardiology, 2002, Feb-20, Volume: 39, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Carotid Artery Diseases; Carotid Artery, Common; Female; Humans; Hypercholesterolemia; Japan; Lipoproteins; Male; Middle Aged; Pravastatin; Probucol; Remission Induction; Time Factors; Tunica Intima; Ultrasonography	2002
Inhibition of platelet aggregation and expression of alpha granule membrane protein 140 and thromboxane B2 with pravastatin therapy for hypercholesterolemia. Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians, 2002, Volume: 13, Issue:1 Topics: Analysis of Variance; Female; Humans; Hypercholesterolemia; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Thromboxane B2	2002
Rosuvastatin demonstrates greater reduction of low-density lipoprotein cholesterol compared with pravastatin and simvastatin in hypercholesterolaemic patients: a randomized, double-blind study. Journal of cardiovascular risk, 2001, Volume: 8, Issue:6 Topics: Cholesterol, LDL; Double-Blind Method; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2001
[Influence of pravastatin on expression of platelet CD(62P) and CD(41) in patients with hypercholesterolemia in vitro and in vivo]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2000, Volume: 21, Issue:9 Topics: Adult; Anticholesteremic Agents; Blood Platelets; Cholesterol; Female; Flow Cytometry; Humans; Hypercholesterolemia; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Membrane Glycoprotein IIb; Pravastatin; Time Factors; Treatment Outcome	2000
Interleukin-6 -174G>C polymorphism and risk of coronary heart disease in West of Scotland coronary prevention study (WOSCOPS). Arteriosclerosis, thrombosis, and vascular biology, 2002, Apr-01, Volume: 22, Issue:4 Topics: Anticholesteremic Agents; C-Reactive Protein; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Female; Fibrinogen; Homozygote; Humans; Hypercholesterolemia; Interleukin-6; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Pravastatin	2002
Pravastatin improves low-density lipoprotein oxidation in renal transplantation. Transplantation proceedings, 2002, Volume: 34, Issue:1 Topics: Adult; Aged; Arteriosclerosis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Transplantation; Lipids; Lipoproteins, LDL; Liver Function Tests; Male; Middle Aged; Oxidation-Reduction; Patient Selection; Postoperative Complications; Pravastatin	2002
A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia. Atherosclerosis, 2002, Volume: 162, Issue:2 Topics: Adult; Aged; Cholesterol; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Quinolines; Safety	2002
Effects of pravastatin on exercise electrocardiography test performance and cardiovascular mortality and morbidity in patients with hypercholesterolemia: Lipid Intervention Study in Kyoto. Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:1 Topics: Adult; Anticholesteremic Agents; Apolipoproteins; Body Constitution; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Electrocardiography; Exercise Test; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Japan; Male; Middle Aged; Morbidity; Pravastatin; Predictive Value of Tests; Time Factors; Triglycerides	2002
[Results of clinical epidemiology and intervention trial of hyperlipidemia in Japan]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Arteriosclerosis; Female; Humans; Hypercholesterolemia; Hyperlipidemias; Japan; Male; Middle Aged; Pravastatin; Prospective Studies; Simvastatin; Treatment Outcome	2002
Increased transforming growth factor-beta(1) circulating levels and production in human monocytes after 3-hydroxy-3-methyl-glutaryl-coenzyme a reductase inhibition with pravastatin. Journal of the American College of Cardiology, 2002, Jun-05, Volume: 39, Issue:11 Topics: Anticholesteremic Agents; Cholesterol; Cross-Over Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Monocytes; Pravastatin; Transforming Growth Factor beta; Triglycerides	2002
Effect of diet and treatment with statins on platelet-dependent thrombin generation in hypercholesterolemic subjects. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2001, Volume: 11, Issue:6 Topics: Adult; Anticholesteremic Agents; Atorvastatin; Blood Platelets; Cholesterol; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hypercholesterolemia; Indoles; Male; Middle Aged; Pravastatin; Pyridines; Pyrroles; Simvastatin; Thrombin; Treatment Outcome	2001
Issues concerning the monitoring of statin therapy in hypercholesterolemic subjects with high plasma lipoprotein(a) levels. Lipids, 2002, Volume: 37, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Enzyme-Linked Immunosorbent Assay; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipoprotein(a); Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Pyridines; Pyrroles; Simvastatin	2002
[Evaluation of the therapeutic efficacy of pravastatin in monothereapy and in association with gemfibrozil in hypercholesterolemia associated with moderate hyperglyceridemia]. Cardiologia (Rome, Italy), 1992, Volume: 37, Issue:11 Topics: Aged; Drug Evaluation; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertriglyceridemia; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Pravastatin	1992
[An evaluation of the efficacy and safety of pravastatin in patients with primary hypercholesterolemia. A Brazilian open multicenter study]. Arquivos brasileiros de cardiologia, 1992, Volume: 59, Issue:4 Topics: Adult; Analysis of Variance; Brazil; Chi-Square Distribution; Female; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin	1992
Treatment of primary hypercholesterolaemia with pravastatin: efficacy and safety over three years. The Medical journal of Australia, 1992, Nov-02, Volume: 157, Issue:9 Topics: Adult; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Safety; Treatment Outcome; Triglycerides	1992
Efficacy and tolerability of simvastatin and pravastatin in patients with primary hypercholesterolemia (multicountry comparative study). The European Study Group. The American journal of cardiology, 1992, Nov-15, Volume: 70, Issue:15 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Triglycerides	1992
[Changes in lipid status during pravastatin treatment]. Minerva medica, 1992, Volume: 83, Issue:11 Topics: Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Gemfibrozil; Humans; Hypercholesterolemia; Lipids; Middle Aged; Pravastatin; Time Factors; Triglycerides	1992
A coronary primary prevention study of Scottish men aged 45-64 years: trial design. The West of Scotland Coronary Prevention Study Group. Journal of clinical epidemiology, 1992, Volume: 45, Issue:8 Topics: Cholesterol; Coronary Disease; Double-Blind Method; Electrocardiography; Health Education; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Primary Prevention; Scotland	1992
Lack of hypotension with lovastatin and pravastatin. Lancet (London, England), 1991, Nov-23, Volume: 338, Issue:8778 Topics: Adult; Aged; Double-Blind Method; Humans; Hypercholesterolemia; Hypotension, Orthostatic; Lovastatin; Male; Middle Aged; Pravastatin	1991
Pravastatin vs gemfibrozil in the treatment of primary hypercholesterolemia. The Italian Multicenter Pravastatin Study I. Archives of internal medicine, 1991, Volume: 151, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Italy; Male; Middle Aged; Naphthalenes; Pravastatin; Triglycerides	1991
[Pravastatin, cholestyramine and gemfibrozil in long-term therapy of primary hypercholesterolemia. An open randomized comparative study]. Medizinische Klinik (Munich, Germany : 1983), 1991, Mar-15, Volume: 86, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholestyramine Resin; Female; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Pravastatin; Triglycerides	1991
Once-daily pravastatin in patients with primary hypercholesterolemia: a dose-response study. Clinical cardiology, 1991, Volume: 14, Issue:2 Topics: Acyl Coenzyme A; Adult; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Placebos; Pravastatin; Time Factors; Triglycerides	1991
Reduction of LDL cholesterol by pravastatin does not influence platelet activation in patients with mild hypercholesterolaemia at risk of coronary heart disease. British journal of clinical pharmacology, 1991, Volume: 32, Issue:1 Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Platelet Activation; Pravastatin; Risk Factors; Thromboxane B2	1991
Lipid-lowering diets in patients taking pravastatin, a new HMG-CoA reductase inhibitor: compliance and adequacy. The American journal of clinical nutrition, 1991, Volume: 54, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Calcium, Dietary; Diet Records; Dietary Fats; Double-Blind Method; Energy Intake; Female; Folic Acid; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Patient Compliance; Pravastatin; Pyridoxine; Vitamin D; Zinc	1991
The effect of pravastatin on plasma lipoprotein and apolipoprotein levels in primary hypercholesterolemia. The Southeastern Michigan Collaborative Group. Archives of internal medicine, 1991, Volume: 151, Issue:11 Topics: Apolipoproteins; Cholesterol, LDL; Dietary Fats; Double-Blind Method; Drug Tolerance; Female; Humans; Hypercholesterolemia; Lipoproteins; Male; Middle Aged; Pravastatin	1991
Comparative effects of two HMG-CoA reductase inhibitors (lovastatin and pravastatin) on serum lipids and lipoproteins. International journal of tissue reactions, 1991, Volume: 13, Issue:2 Topics: Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Middle Aged; Pravastatin	1991
Pravastatin therapy in primary moderate hypercholesterolaemia: changes in metabolism of apolipoprotein B-containing lipoproteins. Journal of internal medicine, 1990, Volume: 227, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Biological Transport; Cholesterol; Double-Blind Method; Heptanoic Acids; Humans; Hypercholesterolemia; Kinetics; Lipoproteins, LDL; Lovastatin; Middle Aged; Naphthalenes; Pravastatin	1990
HMG CoA reductase inhibitors as lipid-lowering agents: five years experience with lovastatin and an appraisal of simvastatin and pravastatin. The Quarterly journal of medicine, 1990, Volume: 74, Issue:274 Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Naphthalenes; Phenotype; Pravastatin; Simvastatin; Time Factors	1990
Pharmacokinetics and pharmacodynamics of pravastatin alone and with cholestyramine in hypercholesterolemia. Clinical pharmacology and therapeutics, 1990, Volume: 48, Issue:2 Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Phospholipids; Pravastatin; Randomized Controlled Trials as Topic; Triglycerides	1990
Efficacy and safety of pravastatin in patients with primary hypercholesterolemia. I. A dose-response study. Atherosclerosis, 1990, Volume: 85, Issue:1 Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Pravastatin; Triglycerides	1990
[Comparison of the effectiveness of the HMG-CoA-reductase inhibitors pravastatin versus colestyramine in hypercholesteremia]. Arzneimittel-Forschung, 1990, Volume: 40, Issue:12 Topics: Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins A; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Pravastatin; Triglycerides	1990
Efficacy and safety of pravastatin in patients with primary hypercholesterolemia. II. Once-daily versus twice-daily dosing. Atherosclerosis, 1990, Volume: 85, Issue:2-3 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Administration Schedule; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Pravastatin; Triglycerides	1990
The relationship between apolipoprotein B-100 and low-density lipoprotein cholesterol after treatment with an HMG CoA reductase inhibitor. American journal of clinical pathology, 1989, Volume: 92, Issue:4 Topics: Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins A; Apolipoproteins B; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Drug Administration Schedule; Heptanoic Acids; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, VLDL; Naphthalenes; Nephelometry and Turbidimetry; Pravastatin; Triglycerides	1989
The effect of CS-514 on serum lipids and apolipoproteins in hypercholesterolemic subjects. JAMA, 1987, Jun-12, Volume: 257, Issue:22 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Double-Blind Method; Drug Evaluation; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipids; Male; Middle Aged; Naphthalenes; Pravastatin	1987
New developments in lipid-lowering therapy: the role of inhibitors of hydroxymethylglutaryl-coenzyme A reductase. Circulation, 1987, Volume: 76, Issue:3 Topics: Animals; Anticholesteremic Agents; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Clinical Trials as Topic; Dogs; Double-Blind Method; Drug Evaluation; Drug Tolerance; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lipoproteins, HDL; Lipoproteins, VLDL; Lovastatin; Middle Aged; Naphthalenes; Pravastatin; Simvastatin; Triglycerides	1987
Dose-dependent hypolipidemic effect of an inhibitor of HMG-CoA reductase, pravastatin (CS-514), in hypercholesterolemic subjects. A double blind test. Atherosclerosis, 1988, Volume: 72, Issue:2-3 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Cholesterol, LDL; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Middle Aged; Naphthalenes; Pravastatin; Time Factors	1988

Other Studies

285 other study(ies) available for pravastatin and Hypercholesterolemia

Article	Year
Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. The American journal of cardiology, 2001, Mar-08, Volume: 87, Issue:5A Topics: Animals; Arteriosclerosis; Cholesterol, LDL; Clinical Trials as Topic; Drug Evaluation, Preclinical; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Molecular Structure; Pyrimidines; Rosuvastatin Calcium; Sulfonamides	2001
Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hyper Journal of medicinal chemistry, 2008, Jan-10, Volume: 51, Issue:1 Topics: Animals; Cholesterol, LDL; Cricetinae; Guinea Pigs; Hepatocytes; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; In Vitro Techniques; Liver; Male; Mesocricetus; Muscle Cells; Pyrazoles; Rats; Stereoisomerism; Structure-Activity Relationship	2008
Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution. Bioorganic & medicinal chemistry letters, 2011, May-01, Volume: 21, Issue:9 Topics: Animals; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Drug Discovery; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Imidazoles; Inhibitory Concentration 50; Liver; Molecular Structure; Pyrazoles; Rats; Tissue Distribution	2011
Diabetogenic effect of pravastatin is associated with insulin resistance and myotoxicity in hypercholesterolemic mice. Journal of translational medicine, 2019, 08-27, Volume: 17, Issue:1 Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Cell Line; Diabetes Mellitus, Experimental; Fasting; Female; Glucose Intolerance; Homeostasis; Hypercholesterolemia; Insulin; Insulin Resistance; Insulin Secretion; Mice, Inbred C57BL; Models, Biological; Muscle Fibers, Skeletal; Muscle Proteins; Myotoxicity; Oxidative Stress; Phosphorylation; Pravastatin; Proteolysis; Receptors, LDL; Signal Transduction; Superoxides	2019
Phytoconstituents of an ethanolic pod extract of Prosopis cineraria triggers the inhibition of HMG-CoA reductase and the regression of atherosclerotic plaque in hypercholesterolemic rabbits. Lipids in health and disease, 2020, Jan-13, Volume: 19, Issue:1 Topics: Animals; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Disease Models, Animal; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Plant Extracts; Plaque, Atherosclerotic; Pravastatin; Prosopis; Rabbits; Triglycerides	2020
Primary Prevention of Cardiocerebrovascular Diseases and Related Deaths According to Statin Type. International journal of environmental research and public health, 2020, 08-30, Volume: 17, Issue:17 Topics: Adult; Aged; Atorvastatin; Cardiovascular Diseases; Cerebrovascular Disorders; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Primary Prevention; Pyrroles; Quinolines; Retrospective Studies; Rosuvastatin Calcium; Simvastatin	2020
Should This Patient Receive Aspirin?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Annals of internal medicine, 2017, 12-05, Volume: 167, Issue:11 Topics: Anticholesteremic Agents; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Hypercholesterolemia; Male; Middle Aged; Platelet Aggregation Inhibitors; Pravastatin; Primary Prevention; Risk Assessment	2017
Clinical Inquiries. Do statins alter the risk or progression of dementia? The Journal of family practice, 2018, Volume: 67, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Cognition; Dementia; Disease Progression; Female; Guidelines as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Simvastatin; United States; United States Food and Drug Administration	2018
Impact of Genetic Variation on Pravastatin Systemic Exposure in Pediatric Hypercholesterolemia. Clinical pharmacology and therapeutics, 2019, Volume: 105, Issue:6 Topics: Adolescent; Child; Female; Genetic Variation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver-Specific Organic Anion Transporter 1; Male; Pravastatin	2019
Severe hypercholesterolaemia in a paediatric patient with congenital analbuminaemia. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2019, Volume: 29, Issue:3 Topics: Child; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypoalbuminemia; Lipids; Mutation; Pravastatin; Serum Albumin, Human; Severity of Illness Index; Time Factors; Treatment Outcome	2019
[Effect of Statins on Glycemic Status and Plasma Adiponectin Concentrations in Patients with Type 2 Diabetes Mellitus and Hypercholesterolemia]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, May-01, Volume: 139, Issue:5 Topics: Adiponectin; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin Resistance; Male; Middle Aged; Molecular Weight; Pravastatin	2019
Long-term statin administration to dams on high-fat diet protects not only them but also their offspring from cardiovascular risk. Annals of nutrition & metabolism, 2013, Volume: 62, Issue:3 Topics: Animals; C-Reactive Protein; Cardiovascular Diseases; Diet, High-Fat; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Kidney; Lactation; Lipids; Male; Maternal Nutritional Physiological Phenomena; Mice; Mice, Inbred C57BL; Pravastatin; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Weaning	2013
What does ALLHAT tell us about dyslipidemia from the hypertension specialist perspective? Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:8 Topics: Anticholesteremic Agents; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Pravastatin	2013
Long-term use of statins reduces the risk of hospitalization for dementia. Atherosclerosis, 2013, Volume: 230, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Atorvastatin; Case-Control Studies; Dementia; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Italy; Logistic Models; Male; Middle Aged; Pravastatin; Pyrroles; Risk; Simvastatin; Time Factors	2013
Lipid-lowering in African Americans in ALLHAT-optimism bias? Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:12 Topics: Anticholesteremic Agents; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Pravastatin	2013
Author response to lipid-lowering in African Americans in ALLHAT-optimism bias? Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:12 Topics: Anticholesteremic Agents; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Pravastatin	2013
Estimation of controlled direct effects in time-varying treatments using structural nested mean models: application to a primary prevention trial for coronary events with pravastatin. Statistics in medicine, 2014, Aug-15, Volume: 33, Issue:18 Topics: Adult; Aged; Biostatistics; Cholesterol; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Models, Statistical; Pravastatin; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Regression Analysis	2014
Co-administration of paroxetine and pravastatin causes deregulation of glucose homeostasis in diabetic rats via enhanced paroxetine exposure. Acta pharmacologica Sinica, 2014, Volume: 35, Issue:6 Topics: Animals; Anticholesteremic Agents; Antidepressive Agents, Second-Generation; Blood Glucose; Cell Line; Depression; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Drug Interactions; Hypercholesterolemia; Insulin; Male; Paroxetine; Pravastatin; Rats; Rats, Sprague-Dawley; Serotonin	2014
Risk of diabetes in patients treated with HMG-CoA reductase inhibitors. Metabolism: clinical and experimental, 2015, Volume: 64, Issue:4 Topics: Aged; Atorvastatin; Diabetes Mellitus; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Pyrimidines; Pyrroles; Quinolines; Retrospective Studies; Risk Factors; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2015
Do statins have a specific drug effect beyond low-density lipoprotein-cholesterol-lowering in the secondary prevention of coronary artery disease? Circulation journal : official journal of the Japanese Circulation Society, 2015, Volume: 79, Issue:1 Topics: Atorvastatin; Cardiovascular Diseases; Female; Humans; Hypercholesterolemia; Male; Myocardial Infarction; Pravastatin	2015
Statin Selection in Qatar Based on Multi-indication Pharmacotherapeutic Multi-criteria Scoring Model, and Clinician Preference. Clinical therapeutics, 2015, Dec-01, Volume: 37, Issue:12 Topics: Atorvastatin; C-Reactive Protein; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Practice Patterns, Physicians'; Pravastatin; Qatar	2015
Fatal rhabdomyolysis following the co-prescription of fusidic acid and pravastatin. Medecine et maladies infectieuses, 2015, Volume: 45, Issue:10 Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Biotransformation; Comorbidity; Cytochrome P-450 Enzyme System; Drug Interactions; Fatal Outcome; Fusidic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Osteitis; Pravastatin; Rhabdomyolysis; Staphylococcal Infections; Tibia	2015
New models for describing outliers in meta-analysis. Research synthesis methods, 2016, Volume: 7, Issue:3 Topics: Algorithms; Cognition Disorders; Cytidine Diphosphate Choline; Dental Caries; Fluorides; Humans; Hypercholesterolemia; Meta-Analysis as Topic; Models, Statistical; Monte Carlo Method; Paroxetine; Placebos; Pravastatin; Regression Analysis; Research Design; Software; Statistics as Topic; Toothpastes	2016
Long-Term Safety and Efficacy of Lowering Low-Density Lipoprotein Cholesterol With Statin Therapy: 20-Year Follow-Up of West of Scotland Coronary Prevention Study. Circulation, 2016, Mar-15, Volume: 133, Issue:11 Topics: Cardiovascular Diseases; Cause of Death; Cholesterol, LDL; Diabetes Complications; Diabetes Mellitus; Follow-Up Studies; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Mortality; Neoplasms; Pravastatin; Proportional Hazards Models; Randomized Controlled Trials as Topic; Scotland; Survival Analysis	2016
Chronic use of pravastatin reduces insulin exocytosis and increases β-cell death in hypercholesterolemic mice. Toxicology, 2016, Feb-17, Volume: 344-346 Topics: Animals; Drug Administration Schedule; Exocytosis; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Pravastatin; Receptors, LDL	2016
Ask the doctor. I am taking pravastatin for high cholesterol, but my numbers are still high. Should I try red yeast rice? Harvard women's health watch, 2013, Volume: 20, Issue:12 Topics: Cholesterol; Cholesterol, LDL; Humans; Hypercholesterolemia; Pravastatin	2013
Neuroprotective Effects of Low-Dose Statins in the Retinal Ultrastructure of Hypercholesterolemic Rabbits. PloS one, 2016, Volume: 11, Issue:5 Topics: Animals; Cholesterol; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluvastatin; Glial Fibrillary Acidic Protein; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Male; Neuroprotective Agents; Pravastatin; Rabbits; Retina; Retinal Vessels	2016
Pravastatin reduces the risk for cardiovascular disease in Japanese hypercholesterolemic patients with impaired fasting glucose or diabetes: diabetes subanalysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese ( Atherosclerosis, 2008, Volume: 199, Issue:2 Topics: Adult; Cardiovascular Diseases; Cholesterol; Diabetes Mellitus; Fasting; Female; Glucose; Humans; Hypercholesterolemia; Japan; Lipids; Male; Middle Aged; Pravastatin; Risk	2008
Cost-effectiveness analysis of rosuvastatin versus atorvastatin, simvastatin, and pravastatin from a Canadian health system perspective. Clinical therapeutics, 2008, Volume: 30, Issue:7 Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Atorvastatin; British Columbia; Cholesterol, HDL; Cholesterol, LDL; Cost-Benefit Analysis; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Triglycerides	2008
Ptosis, diplopia and statins: an association? European journal of neurology, 2008, Volume: 15, Issue:10 Topics: Adult; Atorvastatin; Autoantibodies; Autoimmune Diseases of the Nervous System; Azetidines; Blepharoptosis; Diabetes Complications; Diagnostic Errors; Diplopia; Eyelid Diseases; Ezetimibe; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Myasthenia Gravis; Myocardial Infarction; Pain; Pravastatin; Pyrroles; Receptors, Cholinergic; Recurrence; Strabismus	2008
The relationship between the effect of pravastatin and risk factors for coronary heart disease in Japanese patients with hypercholesterolemia. Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:10 Topics: Adult; Alcohol Drinking; Cholesterol, HDL; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Multivariate Analysis; Pravastatin; Risk Assessment; Risk Factors; Smoking	2008
Influence of pitavastatin on glucose tolerance in patients with type 2 diabetes mellitus. Journal of atherosclerosis and thrombosis, 2008, Volume: 15, Issue:5 Topics: Atorvastatin; Blood Glucose; Diabetes Mellitus, Type 2; Drug Evaluation; Glucose Intolerance; Glycated Hemoglobin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Pyrroles; Quinolines; Retrospective Studies	2008
Metabolic syndrome abating the beneficial effect of pravastatin treatment on adhesion of endothelium by monocytes in subjects with hypercholesterolemia. Metabolism: clinical and experimental, 2009, Volume: 58, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Blood Glucose; C-Reactive Protein; Cell Adhesion; Endothelium, Vascular; Female; Humans; Hypercholesterolemia; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Middle Aged; Monocytes; Patient Selection; Pravastatin; Triglycerides; Young Adult	2009
Risk factors for stroke and lipid-lowering effect of pravastatin on the risk of stroke in Japanese patients with hypercholesterolemia: analysis of data from the MEGA Study, a large randomized controlled trial. Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2 Topics: Adult; Aged; Alcohol Drinking; Cholesterol; Combined Modality Therapy; Comorbidity; Diabetes Mellitus; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Incidence; Japan; Lipoprotein(a); Male; Middle Aged; Obesity; Pravastatin; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Smoking; Stroke	2009
Rosuvastatin for cardiovascular prevention: too many uncertainties. Prescrire international, 2009, Volume: 18, Issue:102 Topics: Aged; Angina, Unstable; Anticholesteremic Agents; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Pravastatin; Pyrimidines; Randomized Controlled Trials as Topic; Rosuvastatin Calcium; Simvastatin; Stroke; Sulfonamides; Uncertainty	2009
Is cyclosporine A transport inhibited by pravastatin via multidrug resistant protein 2? European journal of clinical pharmacology, 2010, Volume: 66, Issue:2 Topics: Biological Transport; Caco-2 Cells; Cell Survival; Cyclosporine; Drug Interactions; Female; Fluoresceins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunosuppressive Agents; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Polymyositis; Pravastatin	2010
Low-dosage statins reduce choroidal damage in hypercholesterolemic rabbits. Acta ophthalmologica, 2011, Volume: 89, Issue:7 Topics: Animals; Anticholesteremic Agents; Cholesterol; Cholesterol, Dietary; Choroid; Choroid Diseases; Disease Models, Animal; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Male; Muscle, Smooth, Vascular; Pravastatin; Rabbits; Triglycerides	2011
Letter by Superko and King regarding article, "Lipid Treatment Assessment Project 2: a multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals". Circulation, 2010, Mar-09, Volume: 121, Issue:9 Topics: Atorvastatin; C-Reactive Protein; Cholesterol, LDL; Female; Genetic Predisposition to Disease; Goals; Guideline Adherence; Health Care Surveys; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kinesins; Male; Middle Aged; Mutation, Missense; Patient Selection; Pravastatin; Pyrroles; Risk	2010
Pitavastatin: the newest HMG-CoA reductase inhibitor. Reviews in cardiovascular medicine, 2010,Winter, Volume: 11, Issue:1 Topics: Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Product Surveillance, Postmarketing; Pyrroles; Quinolines; Simvastatin	2010
Unusual pattern of dyslipidemia in children receiving steroid minimization immunosuppression after renal transplantation. Clinical journal of the American Society of Nephrology : CJASN, 2010, Volume: 5, Issue:8 Topics: Adolescent; Biomarkers; California; Child; Child, Preschool; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunosuppressive Agents; Kidney Transplantation; Male; Pravastatin; Retrospective Studies; Steroids; Time Factors; Transplantation, Homologous; Treatment Outcome; Triglycerides	2010
[Pharmaco-economic optimization of cholesterol-lowering treatment with statins]. Medicina clinica, 2011, Jun-25, Volume: 137, Issue:3 Topics: Atorvastatin; Cholesterol, LDL; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Goals; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Practice Guidelines as Topic; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Spain; Sulfonamides	2011
Glucose-lowering effect of colestimide is associated with baseline HbA1c in type 2 diabetic patients with hypercholesterolemia. Endocrine journal, 2011, Volume: 58, Issue:3 Topics: Aged; Atorvastatin; Blood Glucose; Comorbidity; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Glycated Hemoglobin; Heptanoic Acids; Humans; Hypercholesterolemia; Hypoglycemic Agents; Imidazoles; Lipids; Male; Middle Aged; Multivariate Analysis; Pravastatin; Pyrroles; Quinolines; Resins, Synthetic; Retrospective Studies; Treatment Outcome	2011
APPROACH-J study: design, rationale, and baseline data of the affirmation primary prevention with pravastatin in reduction of occlusive atherosclerotic complications in hypercholesterolemia--Japan study. Journal of atherosclerosis and thrombosis, 2011, Volume: 18, Issue:12 Topics: Adult; Atherosclerosis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Japan; Male; Middle Aged; Pravastatin; Primary Prevention	2011
Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress. Cardiovascular research, 2012, Jun-01, Volume: 94, Issue:3 Topics: Animals; Anticholesteremic Agents; Disease Models, Animal; Hypercholesterolemia; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Pravastatin; Proto-Oncogene Proteins c-akt; Rabbits; Simvastatin	2012
[Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study]. Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2011, Volume: 76, Issue:4 Topics: Aged; Algorithms; Azetidines; Biomarkers; Cardiovascular Diseases; Cerebrovascular Disorders; Cholesterol, LDL; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Ezetimibe; Female; Fluorobenzenes; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Italy; Lovastatin; Male; Medication Adherence; Middle Aged; Pravastatin; Pyrimidines; Retrospective Studies; Risk Assessment; Risk Factors; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2011
N-terminal pro-B-type natriuretic peptide and the prediction of primary cardiovascular events: results from 15-year follow-up of WOSCOPS. European heart journal, 2013, Volume: 34, Issue:6 Topics: Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Electrocardiography; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Pravastatin; Randomized Controlled Trials as Topic; Risk Factors; Scotland	2013
Effects of statins and cholesterol on memory functions in mice. Metabolic brain disease, 2012, Volume: 27, Issue:4 Topics: Acetylcholinesterase; Algorithms; Animals; Avoidance Learning; Brain Chemistry; Cholesterol; Female; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Memory; Mice; Mice, Inbred C57BL; Pravastatin; Simvastatin; Transfer, Psychology	2012
Rhabdomyolysis in a multiple myeloma patient secondary to concurrent treatment with lenalidomide and pravastatin and to lenalidomide alone. International journal of hematology, 2012, Volume: 96, Issue:6 Topics: Amines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Boronic Acids; Bortezomib; Combined Modality Therapy; Creatine Kinase, MM Form; Cyclohexanecarboxylic Acids; Dexamethasone; Drug Synergism; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunologic Factors; Kidney Diseases; Lenalidomide; Melphalan; Middle Aged; Multiple Myeloma; Peripheral Blood Stem Cell Transplantation; Polyneuropathies; Pravastatin; Pyrazines; Rhabdomyolysis; Thalidomide	2012
The enigma of adiponectin. Atherosclerosis, 2013, Volume: 227, Issue:2 Topics: Adiponectin; Diabetes Mellitus, Type 2; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin	2013
A "bad responder" to statins. Cardiology, 2002, Volume: 97, Issue:4 Topics: Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Treatment Failure	2002
Are some statins more equal than others. Diabetes, obesity & metabolism, 2002, Volume: 4, Issue:4 Topics: Anticholesteremic Agents; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Fluorobenzenes; Humans; Hypercholesterolemia; Pravastatin; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Structure-Activity Relationship; Sulfonamides	2002
[Hypothyroidism, pravastatin therapy and myopathy]. Duodecim; laaketieteellinen aikakauskirja, 2002, Volume: 118, Issue:7 Topics: Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypothyroidism; Middle Aged; Muscular Diseases; Pravastatin	2002
Frequency of new coronary events in older persons with peripheral arterial disease and serum low-density lipoprotein cholesterol > or = 125 mg/dl treated with statins versus no lipid-lowering drug. The American journal of cardiology, 2002, Oct-01, Volume: 90, Issue:7 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Female; Follow-Up Studies; Health Services for the Aged; Humans; Hypercholesterolemia; Incidence; Lovastatin; Male; Middle Aged; Myocardial Infarction; New York; Peripheral Vascular Diseases; Pravastatin; Prospective Studies; Simvastatin; Treatment Outcome; Triglycerides	2002
Low-density lipoprotein lowering and atherosclerosis progression: does more mean less? Circulation, 2002, Oct-15, Volume: 106, Issue:16 Topics: Arteriosclerosis; Atorvastatin; Carotid Arteries; Cholesterol; Cholesterol, LDL; Disease Progression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Pravastatin; Pyrroles; Ultrasonography	2002
The ALLHAT lipid lowering trial--less is less. JAMA, 2002, Dec-18, Volume: 288, Issue:23 Topics: Anticholesteremic Agents; Cardiovascular Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Pravastatin	2002
Statins do not meet expectations for lowering low-density lipoprotein cholesterol levels when used in clinical practice. The American journal of medicine, 2002, Dec-01, Volume: 113, Issue:8 Topics: Aged; Atorvastatin; Cardiology; Cholesterol, LDL; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Observer Variation; Patient Compliance; Pravastatin; Probability; Prospective Studies; Pyrroles; Reference Values; Simvastatin; Treatment Failure; Treatment Outcome	2002
Does pravastatin affect circulating levels of soluble TNF receptor 2 in hypercholesterolemic patients? Atherosclerosis, 2003, Volume: 166, Issue:2 Topics: Adult; Blood Chemical Analysis; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Diet Therapy; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Japan; Male; Middle Aged; Multivariate Analysis; Pravastatin; Probability; Prospective Studies; Receptors, Tumor Necrosis Factor; Regression Analysis; Solubility; Statistics, Nonparametric; Treatment Outcome	2003
The PROSPER trial. Lancet (London, England), 2003, Feb-01, Volume: 361, Issue:9355 Topics: Aged; Anticholesteremic Agents; Humans; Hypercholesterolemia; Incidence; Neoplasms; Pravastatin; Primary Prevention; Randomized Controlled Trials as Topic; Research Design	2003
Statin therapy and small fibre neuropathy: a serial electrophysiological study. Journal of the neurological sciences, 2003, Apr-15, Volume: 208, Issue:1-2 Topics: Anticholesteremic Agents; Electric Stimulation; Electrophysiology; Humans; Hypercholesterolemia; Lower Extremity; Male; Middle Aged; Neural Conduction; Peripheral Nervous System Diseases; Pravastatin; Simvastatin	2003
A model to assess the cost effectiveness of statins in achieving the UK National Service Framework target cholesterol levels. PharmacoEconomics, 2003, Volume: 21 Suppl 1 Topics: Atorvastatin; Cholesterol; Clinical Trials as Topic; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Models, Economic; Pravastatin; Pyrroles; Simvastatin; United Kingdom	2003
Massive postoperative rhabdomyolysis following combined CABG/abdominal aortic replacement: a possible association with HMG-CoA reductase inhibitors. Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:5 Topics: Acute Kidney Injury; Aged; Aorta, Abdominal; Coronary Artery Bypass; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Myoglobinuria; Postoperative Complications; Pravastatin; Rhabdomyolysis	2002
More on PROSPER. Lancet (London, England), 2003, Mar-29, Volume: 361, Issue:9363 Topics: Age Factors; Aged; Anticholesteremic Agents; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Stroke; Treatment Outcome	2003
Pilot study describing the use of pravastatin in pediatric renal transplant recipients. Pediatric transplantation, 2003, Volume: 7, Issue:3 Topics: Anticholesteremic Agents; Case-Control Studies; Child; Female; Humans; Hypercholesterolemia; Immunosuppressive Agents; Kidney Transplantation; Male; Pilot Projects; Pravastatin; Retrospective Studies	2003
Apo A-I promoter polymorphism influences basal HDL-cholesterol and its response to pravastatin therapy. Atherosclerosis, 2003, Volume: 168, Issue:2 Topics: Alleles; Anticholesteremic Agents; Apolipoprotein A-I; Cholesterol, HDL; Female; Heterozygote; Humans; Hypercholesterolemia; Male; Middle Aged; Osmolar Concentration; Polymorphism, Genetic; Pravastatin; Promoter Regions, Genetic; Prospective Studies	2003
Pilot study examining the effect of cholesterol lowering on platelet nitric oxide responsiveness and arterial stiffness in subjects with isolated mild hypercholesterolaemia. Clinical and experimental pharmacology & physiology, 2003, Volume: 30, Issue:7 Topics: Adult; Anticholesteremic Agents; Arteries; Blood Platelets; Cholesterol; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Pilot Projects; Pravastatin; Vascular Resistance	2003
[Caution about the use of statins in elderly individuals]. Revista medica de Chile, 2003, Volume: 131, Issue:5 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Clinical Trials as Topic; Humans; Hypercholesterolemia; Pravastatin	2003
Statin face-off. Surprises from the first head-to-head comparison. Time, 2003, Nov-24, Volume: 162, Issue:21 Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Pyrroles; Treatment Outcome; United States	2003
Effect of statins on the progression of bioprosthetic aortic valve degeneration. The American journal of cardiology, 2003, Dec-15, Volume: 92, Issue:12 Topics: Aged; Aortic Valve; Aortic Valve Insufficiency; Aortic Valve Stenosis; Atorvastatin; Bioprosthesis; Coronary Artery Bypass; Coronary Artery Disease; Female; Heart Valve Prosthesis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Pravastatin; Prosthesis Failure; Pyrroles; Retrospective Studies; Simvastatin; Treatment Outcome; Ultrasonography	2003
HMG-CoA reductase inhibitor attenuates platelet adhesion in intestinal venules of hypercholesterolemic mice. American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:4 Topics: Animals; Cholesterol; Endothelial Cells; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestines; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Adhesiveness; Pravastatin; Regional Blood Flow; Venules	2004
Hypercholesterolemia is common after pediatric heart transplantation: initial experience with pravastatin. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2004, Volume: 23, Issue:3 Topics: Adult; Anticholesteremic Agents; Child; Cholesterol; Cohort Studies; Coronary Disease; Female; Heart Transplantation; Humans; Hypercholesterolemia; Immunosuppressive Agents; Male; Postoperative Complications; Pravastatin; Prevalence; Retrospective Studies; Risk Factors; Triglycerides	2004
Cholesterol-lowering independent regression and stabilization of atherosclerotic lesions by pravastatin and by antimonocyte chemoattractant protein-1 therapy in nonhuman primates. Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:8 Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aorta, Abdominal; Aortic Diseases; Arteriosclerosis; Catheterization; Chemokine CCL2; Chemotaxis; Cholesterol; Cytokines; Diet, Atherogenic; DNA, Complementary; Drug Evaluation, Preclinical; Genetic Therapy; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Iliac Artery; Immunoglobulin G; Immunoglobulin M; Inflammation; Macaca fascicularis; Male; Peptidyl-Dipeptidase A; Phenotype; Pravastatin; Random Allocation; Renin; Transfection	2004
[The Prosper-Study: practical consequences?]. Der Internist, 2004, Volume: 45, Issue:5 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Male; Pravastatin; Risk Assessment; Risk Factors; Treatment Outcome; Vascular Diseases	2004
Pharmacogenetic study of statin therapy and cholesterol reduction. JAMA, 2004, Jun-16, Volume: 291, Issue:23 Topics: Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Genotype; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Polymorphism, Single Nucleotide; Pravastatin	2004
[Pravastatin-associated polymyositis, a case report]. Rinsho shinkeigaku = Clinical neurology, 2004, Volume: 44, Issue:1 Topics: Aged; Anticholesteremic Agents; Humans; Hypercholesterolemia; Male; Polymyositis; Pravastatin	2004
[Lower, lower, lower. The LDL goal value of 200 mg/dl is still much too high]. MMW Fortschritte der Medizin, 2004, Mar-25, Volume: 146, Issue:13 Topics: Atorvastatin; Cholesterol, LDL; Clinical Trials as Topic; Coronary Artery Disease; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Myocardial Infarction; Pravastatin; Pyrroles; Reference Values; Risk; Survival Analysis; Survival Rate	2004
[Results of randomized study: intensive lipid lowering treatment stops coronary atherosclerosis]. MMW Fortschritte der Medizin, 2004, Mar-25, Volume: 146, Issue:13 Topics: Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Cholesterol, LDL; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Treatment Outcome; Ultrasonography, Interventional	2004
[Regarding LDL cholesterol: the lower, the better (interview by Dr. Dirk Einecke)]. MMW Fortschritte der Medizin, 2004, Mar-25, Volume: 146, Issue:13 Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hypercholesterolemia; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Treatment Outcome	2004
Updated guidelines support even lower cholesterol levels for at-risk patients. Report on medical guidelines & outcomes research, 2004, Aug-06, Volume: 15, Issue:15 Topics: Anticholesteremic Agents; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Myocardial Infarction; Practice Guidelines as Topic; Pravastatin; Pyrroles; Risk Factors; Risk Reduction Behavior; Simvastatin; Triglycerides; United States	2004
An approach to the residence time distribution for stochastic multi-compartment models. Mathematical biosciences, 2004, Volume: 191, Issue:2 Topics: Anticholesteremic Agents; Body Fluid Compartments; Feedback, Physiological; Humans; Hypercholesterolemia; Markov Chains; Models, Biological; Pharmacokinetics; Pravastatin; Stochastic Processes	2004
Effect of pravastatin on left ventricular mass by activation of myocardial K ATP channels in hypercholesterolemic rabbits. Atherosclerosis, 2004, Volume: 176, Issue:2 Topics: Adenosine Triphosphate; Animals; Anticholesteremic Agents; Disease Models, Animal; Heart; Hypercholesterolemia; Hypertrophy, Left Ventricular; Male; Potassium Channels; Pravastatin; Rabbits	2004
Lessons from the PROVE-IT trial. Higher dose of potent statin better for high-risk patients. Cleveland Clinic journal of medicine, 2004, Volume: 71, Issue:8 Topics: Cardiovascular Diseases; Cholesterol, LDL; Dose-Response Relationship, Drug; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Randomized Controlled Trials as Topic	2004
[Endothelial dysfunction, inflammation and statins: new evidences]. Revista espanola de cardiologia, 2004, Volume: 57, Issue:10 Topics: Animals; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Coronary Circulation; Endothelium, Vascular; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Interleukin-6; Pravastatin; Pyrroles; Rabbits; Time Factors	2004
[Decreasing LDL level moderately or drastically. Is differential therapy with statins available? (interview by Dirk Einecke)]. MMW Fortschritte der Medizin, 2004, Jul-08, Volume: 146, Issue:27-28 Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Drug Approval; Drugs, Generic; Germany; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Pyrroles	2004
Pharmacogenetic study of statin therapy in cholesterol reduction. Current hypertension reports, 2004, Volume: 6, Issue:6 Topics: Anticholesteremic Agents; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Randomized Controlled Trials as Topic	2004
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. 1995. Atherosclerosis. Supplements, 2004, Volume: 5, Issue:3 Topics: Coronary Disease; History, 20th Century; Humans; Hypercholesterolemia; Male; Pravastatin	2004
Rosuvastatin: new preparation. Opt for statins with evidence of efficacy on clinical outcome. Prescrire international, 2004, Volume: 13, Issue:72 Topics: Anticholesteremic Agents; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2004
Electrocardiographic events and cholesterol reduction with pravastatin in patients with hypercholesterolemia: the Hokuriku Lipid Coronary Heart Disease Study-Pravastatin Atherosclerosis Trial. International journal of cardiology, 2005, Mar-30, Volume: 99, Issue:3 Topics: Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Coronary Artery Disease; Electrocardiography; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Risk	2005
Pharmacogenetic study of statin therapy and cholesterol reduction. Current atherosclerosis reports, 2005, Volume: 7, Issue:3 Topics: Cholesterol, LDL; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pharmacogenetics; Polymorphism, Single Nucleotide; Pravastatin; Randomized Controlled Trials as Topic	2005
[Effects of atorvastatin, fluvastatin, pravastatin, and simvastatin on endothelial function, lipid peroxidation, and aortic atherosclerosis in hypercholesterolemic rabbits]. Arquivos brasileiros de cardiologia, 2005, Volume: 84, Issue:4 Topics: Animals; Anticholesteremic Agents; Aortic Diseases; Arteriosclerosis; Atorvastatin; Cholesterol; Cholesterol, LDL; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Hypercholesterolemia; Indoles; Lipid Peroxidation; Male; Malondialdehyde; Pravastatin; Pyrroles; Rabbits; Simvastatin	2005
[The PROVE IT-TIMI-22 study or the biter being bit]. Revue medicale suisse, 2005, Apr-06, Volume: 1, Issue:14 Topics: Anticholesteremic Agents; Atorvastatin; Heptanoic Acids; Humans; Hypercholesterolemia; Pravastatin; Pyrroles	2005
Gitelman's syndrome presenting as intolerance to statin therapy. Annals of clinical biochemistry, 2005, Volume: 42, Issue:Pt 3 Topics: Adult; Amiloride; Cholesterol; Dose-Response Relationship, Drug; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypokalemia; Kidney Diseases; Magnesium; Muscular Diseases; Pain; Potassium; Pravastatin; Spironolactone; Syndrome	2005
Comparison of rosuvastatin with atorvastatin, simvastatin and pravastatin in achieving cholesterol goals and improving plasma lipids in hypercholesterolaemic patients with or without the metabolic syndrome in the MERCURY I trial. Diabetes, obesity & metabolism, 2005, Volume: 7, Issue:4 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Metabolic Syndrome; Middle Aged; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome; Triglycerides	2005
Acute onset and worsening of diabetes concurrent with administration of statins. Endocrine journal, 2005, Volume: 52, Issue:3 Topics: Anticholesteremic Agents; Atorvastatin; Blood Glucose; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Pyrroles	2005
[Intensive LDL lowering to under 80 mg/dl: hypercholesteremia patients with stable coronary disease and diabetes profit especially significantly]. MMW Fortschritte der Medizin, 2005, Aug-18, Volume: 147, Issue:33-34 Topics: Anticholesteremic Agents; Atorvastatin; Cardiovascular Diseases; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Diabetes Complications; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Life Expectancy; Pravastatin; Pyrroles; Risk; Risk Factors; Time Factors	2005
[Pravastatin-induced dermatomyositis]. La Revue de medecine interne, 2005, Volume: 26, Issue:11 Topics: Aged; Anticholesteremic Agents; Dermatomyositis; Female; Humans; Hypercholesterolemia; Pravastatin; Time Factors	2005
How common is rhabdomyolysis in patients receiving lipid-lowering therapy? Nature clinical practice. Cardiovascular medicine, 2005, Volume: 2, Issue:3 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; Creatine Kinase; Drug Therapy, Combination; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Incidence; Middle Aged; Pravastatin; Pyrroles; Retrospective Studies; Rhabdomyolysis; Risk Factors; Simvastatin; United States	2005
Pravastatin reduces thrombogenicity by mechanisms beyond plasma cholesterol lowering. Thrombosis and haemostasis, 2005, Volume: 94, Issue:5 Topics: Animals; Blood Platelets; Cholesterol, Dietary; Endothelium, Vascular; Female; Fibrinogen; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunohistochemistry; Platelet Aggregation; Pravastatin; rhoA GTP-Binding Protein; Risk; Swine; Thrombosis	2005
Effect of pravastatin and atorvastatin on glucose metabolism in nondiabetic patients with hypercholesterolemia. Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:2 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Carbohydrate Metabolism; Diabetes Mellitus; Female; Glucose; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipid Metabolism; Male; Pravastatin; Pyrroles; Retrospective Studies; Treatment Outcome	2006
Vascular endothelial growth factor serum concentrations in hypercholesterolemic patients. Scandinavian journal of clinical and laboratory investigation, 2006, Volume: 66, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Atherosclerosis; C-Reactive Protein; Case-Control Studies; Cholesterol; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Inflammation Mediators; Male; Middle Aged; Neovascularization, Pathologic; Pravastatin; Triglycerides; Vascular Endothelial Growth Factor A	2006
Influences of statins on glucose tolerance in patients with type 2 diabetes mellitus. Journal of atherosclerosis and thrombosis, 2006, Volume: 13, Issue:2 Topics: Aged; Atorvastatin; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glucose Tolerance Test; Glycated Hemoglobin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypoglycemic Agents; Male; Middle Aged; Pravastatin; Pyrroles; Retrospective Studies	2006
Cost-effectiveness analysis of cholesterol-lowering therapies in Spain. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2006, Volume: 6, Issue:3 Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Cholestyramine Resin; Clinical Trials as Topic; Coronary Disease; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Meta-Analysis as Topic; Pravastatin; Pyrroles; Risk Factors; Simvastatin; Spain	2006
Statin therapy induces ultrastructural damage in skeletal muscle in patients without myalgia. The Journal of pathology, 2006, Volume: 210, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Animals; Annexins; Anticholesteremic Agents; Atorvastatin; Biomarkers; Calcium Channels, L-Type; Cholesterol; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron; Middle Aged; Muscle Fibers, Skeletal; Muscle, Skeletal; Pravastatin; Pyrroles; Receptors, LDL; Simvastatin	2006
Plasma cholesteryl ester transfer protein concentrations predict cardiovascular events in patients with coronary artery disease treated with pravastatin. Journal of internal medicine, 2006, Volume: 260, Issue:2 Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Biomarkers; Cardiovascular Diseases; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol, LDL; Coronary Artery Disease; Female; Genetic Markers; Genotype; Glycoproteins; Humans; Hypercholesterolemia; Male; Middle Aged; Polymorphism, Restriction Fragment Length; Pravastatin; Prospective Studies	2006
Pharmacogenetic determinants of variability in lipid-lowering response to pravastatin therapy. Journal of human genetics, 2006, Volume: 51, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Apolipoproteins E; Cholesterol 7-alpha-Hydroxylase; Female; Humans; Hypercholesterolemia; Lipids; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Organic Anion Transporters; Pharmacogenetics; Pravastatin	2006
Statins and cerebral vasomotor reactivity: implications for a new therapy? Stroke, 2006, Volume: 37, Issue:10 Topics: Adult; Animals; Arginine; Atorvastatin; Brain Ischemia; Cerebrovascular Circulation; Clinical Trials, Phase II as Topic; Endothelium, Vascular; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Intracranial Aneurysm; Mice; Middle Cerebral Artery; Nitric Oxide; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Simvastatin; Stroke; Subarachnoid Hemorrhage; Ultrasonography, Doppler, Transcranial; Vasodilation; Vasomotor System; Vasospasm, Intracranial	2006
The effect of 6 months of treatment with pravastatin on serum adiponection concentrations in Japanese patients with coronary artery disease and hypercholesterolemia: a pilot study. Clinical therapeutics, 2006, Volume: 28, Issue:7 Topics: Adiponectin; Aged; Cholesterol; Coronary Artery Disease; Endpoint Determination; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Japan; Male; Middle Aged; Pilot Projects; Pravastatin; Triglycerides	2006
Pravastatin in vivo reduces mononuclear cell migration through endothelial monolayers. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2006, Volume: 27, Issue:4 Topics: Aged; Anticholesteremic Agents; Cell Movement; Endothelium; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypercholesterolemia; Leukocytes, Mononuclear; Male; Matrix Metalloproteinase 9; Middle Aged; Pravastatin; Time Factors; Tumor Necrosis Factor-alpha	2006
Japan: are statins still good for everybody? Lancet (London, England), 2006, Sep-30, Volume: 368, Issue:9542 Topics: Anticholesteremic Agents; Coronary Disease; Diet, Fat-Restricted; Female; Humans; Hypercholesterolemia; Japan; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Risk Factors	2006
Pravastatin: a potential cause for acute pancreatitis. World journal of gastroenterology, 2006, Nov-21, Volume: 12, Issue:43 Topics: Acute Disease; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Middle Aged; Pancreatitis; Pravastatin	2006
Influence of pravastatin on carotid artery structure and function in dyslipidemic HIV-infected patients receiving antiretroviral therapy. AIDS (London, England), 2006, Nov-28, Volume: 20, Issue:18 Topics: Age Factors; Anticholesteremic Agents; Antiretroviral Therapy, Highly Active; Aorta; Blood Pressure; Body Mass Index; Carotid Artery, Common; Female; HIV Infections; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Time Factors; Treatment Outcome; Tunica Intima	2006
The MEGA study. Lancet (London, England), 2006, Dec-09, Volume: 368, Issue:9552 Topics: Cardiovascular Diseases; Diet; Female; Humans; Hypercholesterolemia; Japan; Myocardial Revascularization; Pravastatin; Research Design	2006
The MEGA study. Lancet (London, England), 2006, Dec-09, Volume: 368, Issue:9552 Topics: Atorvastatin; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hypercholesterolemia; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome	2006
Preservation of the blood brain barrier integrity may underlie neuroprotective effects of statins in Alzheimer's disease. Journal of Alzheimer's disease : JAD, 2006, Volume: 10, Issue:4 Topics: Alzheimer Disease; Blood-Brain Barrier; Brain; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Neuroprotective Agents; Pravastatin; Randomized Controlled Trials as Topic; Simvastatin	2006
Comparison of the antiatherosclerotic effects of dihydropyridine calcium channel blocker and HMG-CoA reductase inhibitor on hypercholesterolemic rabbits. Vascular pharmacology, 2007, Volume: 46, Issue:4 Topics: Animals; Aorta, Thoracic; Atherosclerosis; Calcium Channel Blockers; Cholesterol; Dihydropyridines; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperplasia; Male; Pravastatin; Rabbits; RNA, Messenger; Scavenger Receptors, Class E; Time Factors; Tunica Intima; Up-Regulation; Vascular Cell Adhesion Molecule-1; Vasodilation	2007
Acquired ichthyosis with pravastatin. Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:4 Topics: Anticholesteremic Agents; Drug Eruptions; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ichthyosis; Middle Aged; Pravastatin; Upper Extremity	2007
A case of vasospastic angina showing resolution of coronary vasospasm in acetylcholine provocation test corresponding to regression of coronary atherosclerosis. International journal of cardiology, 2008, Mar-28, Volume: 125, Issue:1 Topics: Acetylcholine; Angina Pectoris; Angina Pectoris, Variant; Anticholesteremic Agents; Cholinergic Agents; Coronary Artery Disease; Coronary Vasospasm; Dihydropyridines; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Ultrasonography; Vasodilator Agents	2008
Cholesterol lowering with statins: how WOSCOPS confounded the skeptics. Atherosclerosis. Supplements, 2007, Volume: 8, Issue:2 Topics: Cardiovascular Diseases; Cholesterol; Cohort Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Practice Guidelines as Topic; Pravastatin; Randomized Controlled Trials as Topic; Research Design; Risk Assessment; Risk Factors; Scotland; Time Factors; Treatment Outcome	2007
Physiogenomic association of statin-related myalgia to serotonin receptors. Muscle & nerve, 2007, Volume: 36, Issue:3 Topics: Aged; Aged, 80 and over; Atorvastatin; Female; Genomics; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Muscular Diseases; Pain; Polymorphism, Single Nucleotide; Pravastatin; Pyrroles; Receptors, Serotonin; Simvastatin	2007
The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells. Atherosclerosis, 2008, Volume: 197, Issue:2 Topics: Adult; Animals; Atorvastatin; Forkhead Transcription Factors; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Mice; Mice, Inbred C57BL; Pravastatin; Pyrroles; T-Lymphocytes, Regulatory; Up-Regulation	2008
Primary prevention of coronary artery disease. The New England journal of medicine, 2007, Oct-11, Volume: 357, Issue:15 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Humans; Hypercholesterolemia; Pravastatin; Primary Prevention	2007
Low-density lipoprotein cholesterol (LDL-C) levels and LDL-C goal attainment among elderly patients treated with rosuvastatin compared with other statins in routine clinical practice. The American journal of geriatric pharmacotherapy, 2007, Volume: 5, Issue:3 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Cohort Studies; Coronary Disease; Databases, Factual; Fatty Acids, Monounsaturated; Female; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Managed Care Programs; Odds Ratio; Pravastatin; Pyrimidines; Pyrroles; Retrospective Studies; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2007
Long-term follow-up of the West of Scotland Coronary Prevention Study. The New England journal of medicine, 2008, Jan-10, Volume: 358, Issue:2 Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lymphoma; Pravastatin	2008
Long-term follow-up of the West of Scotland Coronary Prevention Study. The New England journal of medicine, 2008, Jan-10, Volume: 358, Issue:2 Topics: Anticholesteremic Agents; Coronary Disease; Data Interpretation, Statistical; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pravastatin	2008
Lowering LDL-C for optimal protection in high-risk patients. The American journal of managed care, 2008, Volume: 14, Issue:1 Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Coronary Artery Disease; Diabetes Mellitus; Guideline Adherence; Heptanoic Acids; Humans; Hypercholesterolemia; Practice Guidelines as Topic; Pravastatin; Pyrroles; Risk Assessment	2008
'Real-life' reduction in cholesterol with statins, 1993 to 2002. British journal of clinical pharmacology, 2008, Volume: 65, Issue:4 Topics: Cholesterol, LDL; Coronary Disease; Drug Administration Schedule; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Patient Compliance; Pravastatin; Scotland; Simvastatin; Treatment Outcome	2008
Statin treatment in hypercholesterolemic pregnant mice reduces cardiovascular risk factors in their offspring. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:4 Topics: Animals; Anticholesteremic Agents; Blood Pressure; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Female; Hypercholesterolemia; Hypertension; Mice; Mice, Inbred C57BL; Motor Activity; Pravastatin; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors	2008
Metabolic myopathies discovered during investigations of statin myopathy. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2008, Volume: 35, Issue:1 Topics: Aged; Alleles; Creatine Kinase; DNA; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Metabolic Diseases; Middle Aged; Muscular Diseases; Mutation; Neurologic Examination; Pravastatin; Protein Prenylation; Pyridines	2008
Effect of APOE genotype on lipid levels in patients with coronary heart disease during a 3-week inpatient rehabilitation program. Clinical pharmacology and therapeutics, 2008, Volume: 84, Issue:2 Topics: Adult; Aged; Alleles; Apolipoprotein E2; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Decision Making; Fatty Acids, Monounsaturated; Female; Fluvastatin; Genotype; Germany; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Inpatients; Linear Models; Lovastatin; Male; Middle Aged; Multivariate Analysis; Pravastatin; Predictive Value of Tests; Pyridines; Pyrroles; Simvastatin; Triglycerides	2008
Can cheap generic statins achieve national cholesterol lowering targets? Journal of health services research & policy, 2008, Volume: 13, Issue:2 Topics: Anticholesteremic Agents; Drugs, Generic; England; Goals; Hospitals, Public; Humans; Hypercholesterolemia; Outcome Assessment, Health Care; Pravastatin; Quality Indicators, Health Care; Simvastatin	2008
Ezetimibe combined with low-dose statin effectively lowers LDL in protease inhibitor treated patients. AIDS patient care and STDs, 2008, Volume: 22, Issue:6 Topics: Adult; Anticholesteremic Agents; Antiretroviral Therapy, Highly Active; Atorvastatin; Azetidines; Cholesterol, LDL; Drug Administration Schedule; Ezetimibe; Female; Follow-Up Studies; Heptanoic Acids; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hypercholesterolemia; Lopinavir; Male; Middle Aged; Pilot Projects; Pravastatin; Prospective Studies; Pyrroles; Ritonavir; Treatment Outcome	2008
Statins prevent coronary heart disease. Lancet (London, England), 1995, Nov-25, Volume: 346, Issue:8987 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Risk Factors; Simvastatin	1995
Long-term treatment (2 years) with the HMG CoA reductase inhibitors lovastatin or pravastatin in combination with cholestyramine in patients with severe primary hypercholesterolemia. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:3 Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Triglycerides	1993
Lowering cholesterol with drugs and diet. The New England journal of medicine, 1995, Nov-16, Volume: 333, Issue:20 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Humans; Hypercholesterolemia; Male; Pravastatin; Sitosterols	1995
Pharmaco-economic assessment of the HMG-CoA reductase inhibitors. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1994, Volume: 84, Issue:12 Topics: Anticholesteremic Agents; Cost Control; Cost-Benefit Analysis; Health Care Costs; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin	1994
Hyperlipidemia and coronary disease. Correction of the increased thrombogenic potential with cholesterol reduction. Circulation, 1995, Dec-01, Volume: 92, Issue:11 Topics: Animals; Anticholesteremic Agents; Aorta; Blood Platelets; Case-Control Studies; Cholesterol; Cholesterol, LDL; Coronary Disease; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Models, Cardiovascular; Pravastatin; Risk Factors; Swine; Thrombosis; Time Factors; Tunica Media	1995
Pravastatin-associated myopathy. Report of a case. Recenti progressi in medicina, 1995, Volume: 86, Issue:5 Topics: Acute Disease; Aged; Biopsy; Diabetes Mellitus, Type 2; Humans; Hypercholesterolemia; Hypertension; Male; Muscle, Skeletal; Muscular Diseases; Myositis; Pravastatin	1995
Pravastatin versus simvastatin--what happens in the real world? South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1995, Volume: 85, Issue:5 Topics: Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Pravastatin; Product Surveillance, Postmarketing; Simvastatin	1995
Effect of systemic treatment with cholesterol-lowering drugs on the skin barrier function in humans. Acta dermato-venereologica, 1995, Volume: 75, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Biological Availability; Cholesterol; Erythema; Female; Galvanic Skin Response; Humans; Hypercholesterolemia; Irritants; Lovastatin; Male; Middle Aged; Patch Tests; Permeability; Pravastatin; Simvastatin; Skin; Sodium Dodecyl Sulfate; Water Loss, Insensible	1995
[Pravastatin in the treatment of hypercholesterolemia]. Anales de medicina interna (Madrid, Spain : 1984), 1994, Volume: 11, Issue:11 Topics: Cholesterol, LDL; Humans; Hypercholesterolemia; Pravastatin	1994
Long-term safety of statin-fibrate combination treatment in the management of hypercholesterolaemia in patients with coronary artery disease. British heart journal, 1995, Volume: 74, Issue:1 Topics: Adult; Aged; Aspartate Aminotransferases; Bezafibrate; Cohort Studies; Coronary Disease; Creatine Kinase; Drug Therapy, Combination; Female; Fenofibrate; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pravastatin; Retrospective Studies; Simvastatin	1995
Regression of transplant coronary artery disease during chronic HELP therapy: a case study. Atherosclerosis, 1995, Volume: 115, Issue:1 Topics: Arteriosclerosis; Chemical Precipitation; Cholesterol, LDL; Coronary Angiography; Coronary Disease; Extracorporeal Circulation; Fibrinogen; Follow-Up Studies; Heart Transplantation; Humans; Hypercholesterolemia; Lipoprotein(a); Male; Middle Aged; Pravastatin; Time Factors	1995
Effects of simvastatin and pravastatin on endothelium-dependent relaxation in hypercholesterolemic rabbits. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 46, Issue:6 Topics: Acetylcholine; Animals; Anticholesteremic Agents; Aorta, Thoracic; Cholesterol; Endothelium, Vascular; Hypercholesterolemia; In Vitro Techniques; Lovastatin; Male; Pravastatin; Rabbits; Simvastatin; Vasodilation	1994
Amelioration of hypercholesterolaemia by HMG-CoA reductase inhibitor (Pravastatin) improved platelet hyperaggregability in nephrotic patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:12 Topics: Humans; Hypercholesterolemia; Nephrotic Syndrome; Platelet Aggregation; Pravastatin; Serum Albumin; Thromboxane B2	1994
Efficacy and short-term effects of pravastatin, a potent inhibitor of HMG-Co A reductase, on hypercholesterolemia in climacteric women. Journal of medicine, 1994, Volume: 25, Issue:5 Topics: Climacteric; Female; Gonadal Steroid Hormones; Gonadotropins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Middle Aged; Postmenopause; Pravastatin; Premenopause; Time Factors	1994
Effects of acute exercise on the changes of lipid profiles and peroxides, prostanoids, and platelet activation in hypercholesterolemic patients before and after treatment. Prostaglandins, 1994, Volume: 48, Issue:3 Topics: beta-Thromboglobulin; Exercise; Female; Humans; Hypercholesterolemia; Lipid Peroxidation; Lipids; Male; Malondialdehyde; Middle Aged; Peroxides; Platelet Activation; Pravastatin; Prostaglandins; Thromboxanes	1994
[Pravastatin effects on lipoproteins, Lp (a), apo B and apo A-1 in patients with primary hypercholesterolemia]. Arquivos brasileiros de cardiologia, 1994, Volume: 62, Issue:6 Topics: Adult; Aged; Apolipoprotein A-I; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Lipoprotein(a); Lipoproteins; Male; Middle Aged; Pravastatin	1994
Cholesterol malabsorption caused by sitostanol ester feeding and neomycin in pravastatin-treated hypercholesterolaemic patients. European journal of clinical pharmacology, 1994, Volume: 47, Issue:2 Topics: Anticholesteremic Agents; Cholesterol; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Intestinal Absorption; Male; Middle Aged; Neomycin; Pravastatin; Sitosterols	1994
[Treatment of dyslipidemia of the elderly with simvastatin and pravastatin. Effectiveness and tolerance]. La Clinica terapeutica, 1994, Volume: 144, Issue:5 Topics: Aged; Cholesterol; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Middle Aged; Pravastatin; Simvastatin; Triglycerides	1994
Drug treatment of hypercholesterolaemia in a patient with Gilbert's syndrome. Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 4) Topics: Administration, Oral; Bezafibrate; Bilirubin; Colestipol; Gilbert Disease; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Liver; Liver Function Tests; Lovastatin; Male; Middle Aged; Pravastatin; Pyrazines; Simvastatin	1994
[Effects of pravastatin on serum lipids, apoproteins, and lipoprotein (a) in primary hypercholesterolemia]. Minerva medica, 1994, Volume: 85, Issue:6 Topics: Adult; Aged; Apoproteins; Cholesterol; Female; Humans; Hypercholesterolemia; Lipoprotein(a); Male; Middle Aged; Pravastatin	1994
Lovastatin versus pravastatin for hypercholesterolemia. The American journal of cardiology, 1994, Feb-15, Volume: 73, Issue:5 Topics: Cholesterol, LDL; Humans; Hypercholesterolemia; Lovastatin; Pravastatin	1994
"A real world" dose comparison of lovastatin and pravastatin. The American journal of cardiology, 1994, Feb-15, Volume: 73, Issue:5 Topics: Cholesterol; Cholesterol, LDL; Humans; Hypercholesterolemia; Lovastatin; Pravastatin	1994
Effects of pravastatin in dyslipidaemic patients with and without hypertension. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5 Topics: Aged; Antihypertensive Agents; Blood Glucose; Cholesterol; Drug Therapy, Combination; Humans; Hypercholesterolemia; Hypertension; Insulin; Middle Aged; Pravastatin; Triglycerides	1993
[Effectiveness of and tolerance to pravastatin in the short-term treatment of primary hypercholesterolemia]. La Clinica terapeutica, 1994, Volume: 144, Issue:1 Topics: Aged; Cholesterol; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Time Factors	1994
HMG-CoA reductase inhibitor therapy and peripheral neuropathy. Annals of internal medicine, 1994, Jun-01, Volume: 120, Issue:11 Topics: Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Peripheral Nervous System Diseases; Pravastatin	1994
Lovastatin in pravastatin comparative trial: cost-effectiveness. The American journal of cardiology, 1994, Feb-15, Volume: 73, Issue:5 Topics: Cholesterol, LDL; Cost-Benefit Analysis; Humans; Hypercholesterolemia; Lovastatin; Pravastatin	1994
[The long-term effect of HMG-CoA reductase inhibitor to the hypercholesterolemia in the climacterium and its endocrinological change]. Nihon Sanka Fujinka Gakkai zasshi, 1994, Volume: 46, Issue:5 Topics: Adult; Climacteric; Estradiol; Estriol; Female; Follicle Stimulating Hormone; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Luteinizing Hormone; Middle Aged; Pravastatin; Testosterone	1994
Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia. Circulation, 1994, Volume: 89, Issue:6 Topics: Adult; Aged; Cholesterol; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin	1994
The rapid reduction in cardiac events with lipid-lowering therapy: mechanisms and implications. The American journal of cardiology, 1993, Nov-01, Volume: 72, Issue:14 Topics: Cardiovascular Diseases; Humans; Hypercholesterolemia; Pravastatin; Risk Factors	1993
Elevated plasma levels of vascular endothelial cell markers in patients with hypercholesterolemia. American journal of hematology, 1993, Volume: 44, Issue:2 Topics: Adult; Aged; Antithrombin III; Endothelium, Vascular; Female; Fibrin Fibrinogen Degradation Products; Fibrinopeptide A; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Male; Middle Aged; Peptide Hydrolases; Plasminogen Activator Inhibitor 1; Pravastatin; Thrombomodulin; Tissue Plasminogen Activator; von Willebrand Factor	1993
Effect of pravastatin treatment on glucose, insulin, and lipoprotein metabolism in patients with hypercholesterolemia. American heart journal, 1994, Volume: 127, Issue:2 Topics: Adult; Aged; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Female; Glucose Tolerance Test; Humans; Hypercholesterolemia; Insulin; Male; Middle Aged; Pravastatin; Triglycerides	1994
Effect of pravastatin, a HMG CoA reductase inhibitor, on blood lipids and aortic lipidosis in cholesterol-fed White Carneau pigeons. Biochimica et biophysica acta, 1993, Jun-19, Volume: 1181, Issue:3 Topics: Animals; Aorta; Cholesterol; Cholesterol, Dietary; Columbidae; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemias; Lipids; Male; Pravastatin	1993
[Pravastatin in hypercholesterolemia in the elderly. Increase of the caseload and control of the results with a regional study on the elderly population of the Monfalcone and Grado areas]. Minerva medica, 1993, Volume: 84, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Cholesterol; Female; Humans; Hypercholesterolemia; Italy; Lipoproteins, HDL; Male; Middle Aged; Pravastatin; Random Allocation; Triglycerides	1993
Apolipoprotein E polymorphism affects the response to pravastatin on plasma apolipoproteins in diabetic patients. Diabetes research and clinical practice, 1993, Volume: 20, Issue:1 Topics: Adult; Aged; Alleles; Apolipoproteins; Apolipoproteins E; Biomarkers; Diabetes Mellitus, Type 2; Diet, Diabetic; Female; Gene Frequency; Humans; Hypercholesterolemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Pravastatin	1993
Simvastatin, pravastatin and lovastatin: three options for lowering cholesterol. The Nurse practitioner, 1993, Volume: 18, Issue:5 Topics: Anticholesteremic Agents; Drug Costs; Drug Interactions; Humans; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin	1993
Effects of one year of treatment with pravastatin, an HMG-CoA reductase inhibitor, on lipoprotein a. Journal of clinical pharmacology, 1993, Volume: 33, Issue:6 Topics: Adult; Aged; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipoprotein(a); Lipoproteins; Male; Middle Aged; Pravastatin; Time Factors; Triglycerides	1993
Effects of probucol and pravastatin on plasma lipids, activities of postheparin lipoprotein lipase, and lecithin cholesterol acyltransferase and apo A-I containing lipoproteins with and without apo A-II in patients with moderate hypercholesterolemia. Clinical biochemistry, 1993, Volume: 26, Issue:2 Topics: Apolipoprotein A-I; Apolipoprotein A-II; Cholesterol, HDL; Female; Humans; Hypercholesterolemia; Lipoprotein Lipase; Male; Middle Aged; Particle Size; Pravastatin; Probucol	1993
Marked decrease in serum HDL cholesterol levels by combined probucol-pravastatin treatment in hypercholesterolemic NIDDM patients. Diabetes care, 1993, Volume: 16, Issue:5 Topics: Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Middle Aged; Pravastatin; Probucol; Triglycerides	1993
Primary prevention of stroke. The New England journal of medicine, 1996, Apr-25, Volume: 334, Issue:17 Topics: Acyl Coenzyme A; Anticholesteremic Agents; Arteriosclerosis; Cerebrovascular Disorders; Controlled Clinical Trials as Topic; Enzyme Inhibitors; Humans; Hypercholesterolemia; Lovastatin; Meta-Analysis as Topic; Oxidoreductases; Pravastatin; Simvastatin	1996
Prevention of coronary heart disease with pravastatin. The New England journal of medicine, 1996, May-16, Volume: 334, Issue:20 Topics: Anticholesteremic Agents; Coronary Disease; Drug Costs; Female; Humans; Hypercholesterolemia; Male; Pravastatin	1996
Prevention of coronary heart disease with pravastatin. The New England journal of medicine, 1996, May-16, Volume: 334, Issue:20 Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Male; Pravastatin; Survival Analysis	1996
Prevention of coronary heart disease with pravastatin. The New England journal of medicine, 1996, May-16, Volume: 334, Issue:20 Topics: Age Factors; Anticholesteremic Agents; Coronary Disease; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Sex Factors	1996
Pravastatin improves outcome for heart transplant recipients. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1996, Volume: 86 Suppl 2 Topics: Anticholesteremic Agents; Heart Transplantation; Humans; Hypercholesterolemia; Pravastatin	1996
Effects of systemic treatment with statins on skin barrier function and stratum corneum water-holding capacity. Dermatology (Basel, Switzerland), 1996, Volume: 192, Issue:3 Topics: Administration, Oral; Adult; Analysis of Variance; Anticholesteremic Agents; Cell Membrane Permeability; Epidermis; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Water Loss, Insensible	1996
[Effect of pharmacological interventions on progression of coronary atherosclerosis]. Revista espanola de cardiologia, 1996, Volume: 49, Issue:5 Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Pravastatin; Primary Prevention; Risk Factors	1996
Effect of beraprost, a stable prostacyclin analogue, on red blood cell deformability impairment in the presence of hypercholesterolemia in rabbits. Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:4 Topics: Animals; Anticholesteremic Agents; Dose-Response Relationship, Drug; Epoprostenol; Erythrocyte Deformability; Female; Hemorheology; Hypercholesterolemia; Platelet Aggregation Inhibitors; Pravastatin; Rabbits	1996
[Effect of cholestyramine on angiopathies in cholesterol-fed mice and diabetic mice]. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1995, Volume: 31, Issue:6 Topics: Animals; Anticholesteremic Agents; Cholesterol, Dietary; Cholestyramine Resin; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Hypercholesterolemia; Male; Mice; Mice, Inbred ICR; Pravastatin; Vascular Diseases; Vasodilation	1995
Urinary excretion of mevalonic acid as an indicator of cholesterol synthesis. Journal of lipid research, 1996, Volume: 37, Issue:10 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Circadian Rhythm; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Mevalonic Acid; Middle Aged; Pravastatin; Reproducibility of Results; Simvastatin; Xanthomatosis, Cerebrotendinous	1996
Cost effectiveness of lowering cholesterol. Statin treatment should be started early. BMJ (Clinical research ed.), 1996, Nov-02, Volume: 313, Issue:7065 Topics: Cardiovascular Diseases; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Simvastatin	1996
Cost effectiveness of lowering cholesterol. Costs in general practice. BMJ (Clinical research ed.), 1996, Nov-02, Volume: 313, Issue:7065 Topics: Cost-Benefit Analysis; Drug Costs; Family Practice; Humans; Hypercholesterolemia; Pravastatin; Scotland	1996
Beneficial effects of statins. Lancet (London, England), 1996, Dec-07, Volume: 348, Issue:9041 Topics: Anticholesteremic Agents; Fibrinogen; Humans; Hypercholesterolemia; Lovastatin; Platelet Aggregation; Pravastatin; Simvastatin	1996
More on pravastatin and coronary disease. The New England journal of medicine, 1996, 10-17, Volume: 335, Issue:16 Topics: Anticholesteremic Agents; Coronary Disease; Cost-Benefit Analysis; Humans; Hypercholesterolemia; Pravastatin	1996
Improvement of erythrocyte deformability by cholesterol-lowering therapy with pravastatin in hypercholesterolemic patients. Metabolism: clinical and experimental, 1997, Volume: 46, Issue:3 Topics: Adult; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Erythrocyte Deformability; Erythrocytes; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies	1997
[Pharmaco-economic aspects of hypolipidemic treatment]. Revue medicale de Liege, 1997, Volume: 52, Issue:1 Topics: Anticholesteremic Agents; Cost-Benefit Analysis; Economics, Pharmaceutical; Humans; Hypercholesterolemia; Models, Economic; Pravastatin; Value of Life	1997
Hemodynamic changes associated with reduction in total cholesterol by treatment with the HMG-CoA reductase inhibitor pravastatin. Atherosclerosis, 1997, Volume: 130, Issue:1-2 Topics: Anticholesteremic Agents; Blood Pressure; Cardiac Output; Cholesterol; Electrocardiography; Female; Heart Rate; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Vascular Resistance	1997
Recent developments in coronary heart disease prevention: the Scandinavian and west of Scotland studies. Tennessee medicine : journal of the Tennessee Medical Association, 1997, Volume: 90, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Enzyme Inhibitors; Female; Finland; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Morbidity; Pravastatin; Randomized Controlled Trials as Topic; Risk Factors; Scotland; Simvastatin	1997
[Value of the CSE-inhibitor Pravastatin in the lowering of cholesterol after heart and kidney transplantation]. Deutsche medizinische Wochenschrift (1946), 1997, Volume: 122, Issue:3 Suppl Topics: Anticholesteremic Agents; Heart Transplantation; Humans; Hypercholesterolemia; Kidney Transplantation; Postoperative Complications; Pravastatin	1997
Platelet-dependent thrombin generation in patients with hyperlipidemia. Journal of the American College of Cardiology, 1997, Volume: 30, Issue:1 Topics: Adult; Anticholesteremic Agents; Blood Coagulation; Blood Platelets; Confounding Factors, Epidemiologic; Female; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lipoprotein(a); Male; Middle Aged; Phospholipids; Platelet Aggregation; Pravastatin; Prostaglandins; Thrombin	1997
Effects of an HMG-CoA reductase inhibitor, pravastatin, and bile sequestering resin, cholestyramine, on plasma plant sterol levels in hypercholesterolemic subjects. Journal of atherosclerosis and thrombosis, 1995, Volume: 2, Issue:1 Topics: Acyl Coenzyme A; Adult; Anticholesteremic Agents; Cholestyramine Resin; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Phytosterols; Pravastatin	1995
Lipid-lowering drugs and mortality. The British journal of psychiatry : the journal of mental science, 1997, Volume: 170 Topics: Cholestyramine Resin; Coronary Disease; Humans; Hypercholesterolemia; Hypolipidemic Agents; Pravastatin; Treatment Outcome	1997
Cholesterol-lowering drugs for primary prevention? The WOSCOP Study. Pharmacological research, 1997, Volume: 35, Issue:3 Topics: Anticholesteremic Agents; Cholesterol; Coronary Disease; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Risk Factors; Scotland	1997
Cholesterol and coronary heart disease: new data from the WOSCOP Study. Pharmacological research, 1997, Volume: 35, Issue:3 Topics: Anticholesteremic Agents; Cholesterol; Coronary Disease; Double-Blind Method; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Pravastatin; Randomized Controlled Trials as Topic; Scotland	1997
Smoking cessation as a rigorous primary intervention for coronary events in middle-aged men. A commentary based on the WOSCOP findings. West of Scotland Coronary Prevention Study. European heart journal, 1997, Volume: 18, Issue:7 Topics: Anticholesteremic Agents; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Pravastatin; Randomized Controlled Trials as Topic; Risk Factors; Smoking Cessation	1997
[The mechanism of action of hypolipidemic drugs]. Revue medicale de Liege, 1997, Volume: 52, Issue:6 Topics: Adipose Tissue; Anticholesteremic Agents; Cholesterol, LDL; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Hypolipidemic Agents; Indoles; Lipase; Lipid Peroxidation; Lipoproteins, VLDL; Liver; Lovastatin; Microbodies; Nuclear Proteins; Pravastatin; Receptors, Cytoplasmic and Nuclear; Receptors, LDL; Simvastatin; Transcription Factors	1997
Effects of fluvastatin on leukocyte-endothelial cell adhesion in hypercholesterolemic rats. Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:8 Topics: Animals; Anticholesteremic Agents; Cell Adhesion; Cell Movement; Cholesterol, Dietary; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Pravastatin; Rats; Rats, Sprague-Dawley	1997
HMG-CoA reductase inhibitors reduce stroke risk, total mortality. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997, Oct-01, Volume: 54, Issue:19 Topics: Cerebrovascular Disorders; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Meta-Analysis as Topic; Mortality; Pravastatin; Simvastatin	1997
Therapy and clinical trials. Current opinion in lipidology, 1997, Volume: 8, Issue:5 Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Simvastatin	1997
"Statin" drugs, mortality, and stroke prevention. The Journal of family practice, 1997, Volume: 45, Issue:4 Topics: Cerebrovascular Disorders; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Meta-Analysis as Topic; Mortality; Pravastatin; Randomized Controlled Trials as Topic; Reproducibility of Results; Simvastatin	1997
Treatment goals for low-density lipoprotein cholesterol in the secondary prevention of coronary heart disease: absolute levels or extent of lowering? The American journal of cardiology, 1997, Nov-15, Volume: 80, Issue:10 Topics: Adult; Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Plasmapheresis; Pravastatin; Regression Analysis; Risk Factors; Simvastatin	1997
Rapid reversal of endothelial dysfunction in hypercholesterolaemic rabbits treated with simvastatin and pravastatin. Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:12 Topics: Animals; Anticholesteremic Agents; Aorta, Thoracic; Cholesterol; Endothelium, Vascular; Hypercholesterolemia; Male; Malondialdehyde; Muscle Relaxation; Pravastatin; Rabbits; Simvastatin	1997
A retrospective drug utilization evaluation of antihyperlipidaemic agents in a medical centre in Taiwan. Journal of clinical pharmacy and therapeutics, 1997, Volume: 22, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Child; Drug Monitoring; Drug Prescriptions; Drug Utilization; Female; Guidelines as Topic; Humans; Hypercholesterolemia; Insurance, Health; Lovastatin; Male; Middle Aged; Pravastatin; Random Allocation; Retrospective Studies; Taiwan	1997
Direct effects of statins on the vascular wall. Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Cell Division; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Male; Middle Aged; Muscle, Smooth, Vascular; Myocardium; Pravastatin	1998
[Assessment of short-term effects of awareness programs and pravastatin therapy on subjects from private clinics at high risk for cardiovascular disease]. Arquivos brasileiros de cardiologia, 1997, Volume: 69, Issue:4 Topics: Adult; Aged; Blood Pressure; Body Weight; Cardiovascular Diseases; Cholesterol; Evaluation Studies as Topic; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Program Evaluation; Risk Factors	1997
Cholesterol drugs revisited. Harvard health letter, 1998, Volume: 23, Issue:9 Topics: Anticholesteremic Agents; Cholesterol, LDL; Humans; Hypercholesterolemia; Pravastatin; Simvastatin	1998
Atherosclerosis in Marek's disease virus infected hypercholesterolemic roosters is reduced by HMGCoA reductase and ACE inhibitor therapy. Cardiovascular research, 1998, Volume: 38, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Carotid Arteries; Chickens; Cholesterol; Disease Models, Animal; Herpesvirus 2, Gallid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Isoquinolines; Lymphocytes; Marek Disease; Pravastatin; Quinapril; Tetrahydroisoquinolines	1998
Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study) The American journal of cardiology, 1998, Aug-01, Volume: 82, Issue:3 Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome	1998
Effect of pravastatin on plasma ketone bodies in diabetics with hypercholesterolemia. The Tohoku journal of experimental medicine, 1998, Volume: 185, Issue:1 Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aged; Aged, 80 and over; Body Mass Index; Cholesterol; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Humans; Hydroxybutyrates; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ketone Bodies; Male; Middle Aged; Pravastatin	1998
[Comparison of hypercholesterolemic men and women at high risk for atherosclerosis. Study of risk factors and response to pravastatin treatment]. Arquivos brasileiros de cardiologia, 1998, Volume: 70, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Arteriosclerosis; Blood Pressure; Body Weight; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged; Patient Selection; Pravastatin; Risk Factors; Sex Factors	1998
Preventing coronary artery disease in the West of Scotland: implications for primary prevention. The American journal of cardiology, 1998, Nov-26, Volume: 82, Issue:10B Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Primary Prevention; Randomized Controlled Trials as Topic; Scotland	1998
The management of hypercholesterolaemia in patients with coronary artery disease referred for coronary angiography. International journal of cardiology, 1998, Dec-31, Volume: 67, Issue:3 Topics: Aged; Anticholesteremic Agents; Cholesterol; Cohort Studies; Coronary Angiography; Coronary Disease; Data Interpretation, Statistical; Diabetes Complications; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Pravastatin; Risk Factors; Simvastatin; Smoking; Treatment Outcome	1998
[Action of pravastatin treatment on blood levels of homocysteine]. Minerva cardioangiologica, 1998, Volume: 46, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Female; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Time Factors	1998
Treating average cholesterol levels in patients with coronary heart disease. The Journal of family practice, 1999, Volume: 48, Issue:2 Topics: Adult; Aged; Cholesterol; Coronary Disease; Double-Blind Method; Female; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Multicenter Studies as Topic; Pravastatin; Randomized Controlled Trials as Topic; Treatment Outcome	1999
Chronic creatine kinase elevation not associated with HMG-CoA reductase inhibitor treatment. The Annals of pharmacotherapy, 1999, Volume: 33, Issue:2 Topics: Biomarkers, Tumor; Creatine Kinase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prostatic Neoplasms; Renal Insufficiency	1999
Statins and PHARMAC. The New Zealand medical journal, 1999, Feb-26, Volume: 112, Issue:1082 Topics: Anticholesteremic Agents; Drug Administration Schedule; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Pravastatin; Publishing; Simvastatin; Treatment Outcome	1999
Double filtration plasmapheresis maintains normal adhesion molecule levels. Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis, 1998, Volume: 2, Issue:3 Topics: Anticholesteremic Agents; Arteriosclerosis; Biomarkers; Cell Adhesion Molecules; Cholesterol; Disease Progression; Endothelium, Vascular; Filtration; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Intercellular Adhesion Molecule-1; Myocardial Ischemia; Peripheral Vascular Diseases; Plasmapheresis; Pravastatin; Thrombomodulin; Vascular Cell Adhesion Molecule-1; von Willebrand Factor	1998
By the way, doctor. I have high cholesterol, and have been taking Mevacor (lovastatin) for two years. Recently, I was switched to Pravachol (pravastatin) because my insurance company would no longer pay for Mevacor. Is it as good? Harvard women's health watch, 1999, Volume: 6, Issue:10 Topics: Anticholesteremic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pravastatin	1999
Acute cholestatic hepatitis associated with pravastatin. The American journal of gastroenterology, 1999, Volume: 94, Issue:5 Topics: Acute Disease; Anticholesteremic Agents; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Male; Middle Aged; Pravastatin	1999
Rationale, design, and baseline results of the Pravastatin-to-Simvastatin Conversion Lipid Optimization Program (PSCOP). American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Jun-01, Volume: 56, Issue:11 Topics: Aged; Anticholesteremic Agents; California; Cholesterol, LDL; Coronary Disease; Drug Administration Schedule; Female; Health Planning; Hospitals, Veterans; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged; Pharmacy Service, Hospital; Pravastatin; Prospective Studies; Simvastatin	1999
Cholesterol lowering. Should it continue to be the last thing we do? Circulation, 1999, Jun-29, Volume: 99, Issue:25 Topics: Anticholesteremic Agents; Blood Platelets; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Drug Administration Schedule; Endothelium, Vascular; Humans; Hypercholesterolemia; Pravastatin; Vasodilation	1999
Inhibition of proinflammatory cytokine production by pravastatin. Lancet (London, England), 1999, Mar-20, Volume: 353, Issue:9157 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol; Cytokines; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation Mediators; Interleukin-1; Interleukin-6; Interleukin-8; Male; Middle Aged; Pravastatin; Receptors, Interleukin-1; Tumor Necrosis Factor-alpha	1999
Gender differences in blood thrombogenicity in hyperlipidemic patients and response to pravastatin. The American journal of cardiology, 1999, Sep-15, Volume: 84, Issue:6 Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Female; Fibrinogen; Fibrinolysis; Humans; Hypercholesterolemia; Male; Middle Aged; Peptide Fragments; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Pravastatin; Prothrombin; Sex Factors; Thrombin; Thrombophilia; Triglycerides	1999
Rhabdomyolysis associated with pravastatin treatment for major depression. Psychiatry and clinical neurosciences, 1999, Volume: 53, Issue:4 Topics: Aged; Anticholesteremic Agents; Antidepressive Agents; Depressive Disorder, Major; Drug Interactions; Female; Humans; Hypercholesterolemia; Pravastatin; Rhabdomyolysis	1999
The University of California at Los Angeles experience in heart transplantation. Clinical transplants, 1998 Topics: Adult; Age Factors; Anticholesteremic Agents; Female; Graft Survival; Heart Transplantation; Hospitals, University; Humans; Hypercholesterolemia; Los Angeles; Male; Middle Aged; Postoperative Complications; Pravastatin; Retrospective Studies; Survival Rate; Tissue Donors; Waiting Lists	1998
After 4S, CARE and LIPID--is evidence-based medicine being practised? Atherosclerosis, 1999, Sep-09, Volume: 147 Suppl 1 Topics: Cholesterol; Clinical Trials as Topic; Coronary Disease; Evidence-Based Medicine; Humans; Hypercholesterolemia; Pravastatin; Risk Factors; Simvastatin	1999
Pravastatin restored the infarct size-limiting effect of ischemic preconditioning blunted by hypercholesterolemia in the rabbit model of myocardial infarction. Journal of the American College of Cardiology, 1999, Volume: 34, Issue:7 Topics: 5'-Nucleotidase; Animals; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Heart Ventricles; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Pravastatin; Rabbits; Treatment Outcome; Triglycerides	1999
Laser-assisted optical rotational red cell analyzer (LORCA) in clinical practice. Hemorheological kinetics and tissue oxygenation. Advances in experimental medicine and biology, 1999, Volume: 471 Topics: Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Calcium Channel Blockers; Erythrocytes; Female; Hemorheology; Humans; Hypercholesterolemia; Hypertension; Hypertriglyceridemia; Kinetics; Lasers; Male; Middle Aged; Oxygen; Pravastatin	1999
Cost-effectiveness of cholesterol-lowering therapies according to selected patient characteristics. Annals of internal medicine, 2000, May-16, Volume: 132, Issue:10 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Computer Simulation; Coronary Disease; Cost of Illness; Cost-Benefit Analysis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Practice Guidelines as Topic; Pravastatin; Quality-Adjusted Life Years; Risk Factors; Sensitivity and Specificity; Sex Factors; Simvastatin	2000
Which statin is most efficient for the treatment of hypercholesterolemia? A cost-effectiveness analysis. Clinical therapeutics, 1999, Volume: 21, Issue:11 Topics: Administration, Oral; Algorithms; Cholesterol, LDL; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Models, Economic; Pravastatin; Simvastatin; Treatment Outcome	1999
[Coronary heart disease: grave deficiencies in secondary prevention. Almost no one is concerned with blood lipids]. MMW Fortschritte der Medizin, 2000, Jun-15, Volume: 142, Issue:24 Topics: Aged; Anticholesteremic Agents; Combined Modality Therapy; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Pravastatin; Recurrence; Simvastatin; Survival Rate	2000
Secondary prevention of hypercholesterolaemia: results of an audit conducted in South Wales. Heart (British Cardiac Society), 2000, Volume: 84, Issue:2 Topics: Aged; Anticholesteremic Agents; Cholesterol; Coronary Disease; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Medical Audit; Myocardial Infarction; Pravastatin; Treatment Outcome	2000
A need to redefine the consensus on the use of statins in coronary heart disease prevention. European heart journal, 2000, Volume: 21, Issue:19 Topics: Anticholesteremic Agents; Cholesterol; Clinical Trials as Topic; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Practice Guidelines as Topic; Pravastatin	2000
Cholesterol lowering with pravastatin improves resistance artery endothelial function: report of six subjects with normal coronary arteriograms. Chest, 2000, Volume: 118, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Coronary Angiography; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Risk Factors; Vascular Resistance	2000
Is there a connection between the concentration of cholesterol circulating in plasma and the rate of neuritic plaque formation in Alzheimer disease? Archives of neurology, 2000, Volume: 57, Issue:10 Topics: Alzheimer Disease; Amyloid beta-Peptides; Anticholesteremic Agents; Apolipoproteins E; Cholesterol; Clinical Trials as Topic; Humans; Hypercholesterolemia; Neurites; Neurofibrillary Tangles; Pravastatin	2000
Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group. The New England journal of medicine, 2000, Oct-19, Volume: 343, Issue:16 Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Anticholesteremic Agents; Biomarkers; C-Reactive Protein; Case-Control Studies; Cholesterol; Coronary Disease; Fibrinogen; Humans; Hypercholesterolemia; Inflammation; Leukocyte Count; Logistic Models; Male; Middle Aged; Myocardial Infarction; Phospholipases A; Phospholipases A2; Pravastatin; Risk Factors; Triglycerides	2000
Development of tachyphylaxis among patients taking HMG CoA reductase inhibitors. The American journal of cardiology, 2000, Nov-15, Volume: 86, Issue:10 Topics: Atorvastatin; Cholesterol, LDL; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Least-Squares Analysis; Linear Models; Lovastatin; Nonlinear Dynamics; Pravastatin; Pyrroles; Retrospective Studies; Simvastatin; Tachyphylaxis; Time Factors	2000
The low-density lipoprotein cholesterol-lowering effect of pravastatin and factors associated with achieving targeted low-density lipoprotein levels in an African-American population. Pharmacotherapy, 2000, Volume: 20, Issue:12 Topics: Anticholesteremic Agents; Black or African American; Black People; Cholesterol, LDL; Cohort Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins, LDL; Logistic Models; Male; Middle Aged; Patient Compliance; Pravastatin; Retrospective Studies; Risk Factors; Treatment Outcome	2000
Effects of initial and long-term lipid-lowering therapy on vascular wall characteristics. Atherosclerosis, 2001, Volume: 154, Issue:1 Topics: Adult; Blood Flow Velocity; Carotid Arteries; Electric Impedance; Femoral Artery; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Middle Aged; Pravastatin; Pulse; Retrospective Studies; Simvastatin; Time Factors; Tunica Intima; Tunica Media; Ultrasonography	2001
[Toxic liver damage caused by HMG-CoA reductase inhibitor]. Medizinische Klinik (Munich, Germany : 1983), 2000, Nov-15, Volume: 95, Issue:11 Topics: Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver Function Tests; Male; Middle Aged; Pravastatin; Simvastatin	2000
[Influence of pravastatin therapy on expression of P-selectin]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 1998, Volume: 19, Issue:9 Topics: Female; Humans; Hypercholesterolemia; Male; Middle Aged; P-Selectin; Platelet Aggregation; Pravastatin	1998
Is a statin a statin? International journal of clinical practice, 2001, Volume: 55, Issue:2 Topics: Anticholesteremic Agents; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Pravastatin; Simvastatin	2001
[Effect on plasma fibrinogen of hypercholesterolaemia treatment with pravastatin]. Atencion primaria, 2001, Apr-15, Volume: 27, Issue:6 Topics: Anticholesteremic Agents; Female; Fibrinogen; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Prospective Studies	2001
[Acute coronary syndrome. Early lipid reduction decreases risk of recurrence]. MMW Fortschritte der Medizin, 2001, Apr-19, Volume: 143, Issue:16 Topics: Angina, Unstable; Cholesterol, LDL; Humans; Hypercholesterolemia; Myocardial Infarction; Pravastatin; Randomized Controlled Trials as Topic; Recurrence	2001
Reassuring effect of pravastatin on natural killer cell activity in stable renal transplant patients. Transplantation, 2001, Apr-27, Volume: 71, Issue:8 Topics: Anticholesteremic Agents; Azathioprine; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cyclosporine; Cytotoxicity, Immunologic; Humans; Hypercholesterolemia; Immunosuppressive Agents; K562 Cells; Kidney Function Tests; Kidney Transplantation; Killer Cells, Natural; Leukocyte Count; Liver Function Tests; Lymphocyte Count; Postoperative Complications; Pravastatin; Triglycerides	2001
Randomized clinical trials and recent patterns in the use of statins. American heart journal, 2001, Volume: 141, Issue:6 Topics: Aged; Anticholesteremic Agents; Coronary Disease; Drug Utilization; Female; Health Surveys; Humans; Hypercholesterolemia; Male; Middle Aged; Practice Patterns, Physicians'; Pravastatin; Randomized Controlled Trials as Topic; Simvastatin; United States	2001
Protective effects of Saiko-ka-ryukotsu-borei-to (Chai-Hu-Jia-Long-Gu-Mu-Li-Tang) against atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits. Pharmacological research, 2001, Volume: 43, Issue:5 Topics: Animals; Anticholesteremic Agents; Apolipoproteins B; Apolipoproteins E; Arteriosclerosis; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Female; Gene Expression; Hypercholesterolemia; Lipids; Liver; Pravastatin; Rabbits; Receptors, LDL; RNA, Messenger; Spectrophotometry, Ultraviolet	2001
Simvastatin-associated memory loss. Pharmacotherapy, 2001, Volume: 21, Issue:6 Topics: Anticholesteremic Agents; Humans; Hypercholesterolemia; Male; Memory Disorders; Middle Aged; Pravastatin; Recovery of Function; Simvastatin	2001
Effect of bezafibrate or pravastatin on serum lipid levels and albuminuria in NIDDM patients. Journal of atherosclerosis and thrombosis, 2000, Volume: 7, Issue:2 Topics: Albuminuria; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins B; Bezafibrate; Blood Pressure; Case-Control Studies; Cholesterol; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; Hypercholesterolemia; Hypolipidemic Agents; Insulin; Lipids; Male; Middle Aged; Pravastatin	2000
Statins enhance arachidonic acid synthesis in hypercholesterolemic patients. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2001, Volume: 11, Issue:2 Topics: Anticholesteremic Agents; Arachidonic Acid; Cholesterol; Cholesterol, LDL; Diet, Reducing; Fatty Acids; Female; Fenofibrate; Humans; Hypercholesterolemia; Longitudinal Studies; Male; Middle Aged; Pravastatin; Simvastatin; Triglycerides	2001
Effect of cholesterol-lowering therapy on endothelial function. Circulation, 2001, Jul-10, Volume: 104, Issue:2 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Circulation; Coronary Disease; Endothelium, Vascular; Humans; Hypercholesterolemia; Infusions, Intra-Arterial; Microcirculation; Pravastatin; Simvastatin; Vascular Resistance; Vasomotor System	2001
Statins and dementia. Archives of neurology, 2001, Volume: 58, Issue:7 Topics: Anticholesteremic Agents; Cognition; Cognition Disorders; Dose-Response Relationship, Drug; Humans; Hypercholesterolemia; Lovastatin; Pravastatin; Randomized Controlled Trials as Topic; Selection Bias; Simvastatin	2001
Cholesterol-lowering drugs. Some drugs with demonstrated efficacy but different benefits in primary and secondary prevention. Prescrire international, 1999, Volume: 8, Issue:42 Topics: Anticholesteremic Agents; Bezafibrate; Cholestyramine Resin; Clinical Trials as Topic; Clofibrate; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Myocardial Infarction; Pravastatin; Treatment Outcome	1999
The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs. Metabolism: clinical and experimental, 2001, Volume: 50, Issue:10 Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, Dietary; Dogs; Drug Combinations; Drug Synergism; Ezetimibe; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Lovastatin; Male; Pravastatin; Simvastatin; Time Factors	2001
HMG-CoA reductase inhibitors reduce vascular monocyte chemotactic protein-1 expression in early lesions from hypercholesterolemic swine independently of their effect on plasma cholesterol levels. Atherosclerosis, 2001, Volume: 159, Issue:1 Topics: Animals; Aorta; Arteries; Arteriosclerosis; Atorvastatin; Carotid Arteries; Chemokine CCL2; Cholesterol; Coronary Vessels; Down-Regulation; Femoral Artery; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Iliac Artery; Immunohistochemistry; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pravastatin; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine	2001
Three HIV-treating physicians express their professional opinions regarding a case scenario. Research initiative, treatment action : RITA, 2000, Volume: 6, Issue:3 Topics: CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Wasting Syndrome; Humans; Hypercholesterolemia; Male; Middle Aged; Practice Patterns, Physicians'; Pravastatin; Reverse Transcriptase Inhibitors; Viral Load	2000
In patients with heart disease, is the benefit of lipid-lowering therapy with statins similar in older patients to that in younger patients? The Journal of family practice, 2001, Volume: 50, Issue:11 Topics: Adult; Age Factors; Aged; Anticholesteremic Agents; Cause of Death; Coronary Disease; Evidence-Based Medicine; Humans; Hypercholesterolemia; Middle Aged; Patient Selection; Pravastatin; Risk Factors; Treatment Outcome	2001
Cost-effectiveness analysis of applying the Cholesterol and Recurrent Events (CARE) study protocol in Hong Kong. Hong Kong medical journal = Xianggang yi xue za zhi, 2001, Volume: 7, Issue:4 Topics: Adult; Aged; Clinical Protocols; Cohort Studies; Cost-Benefit Analysis; Female; Health Care Costs; Hong Kong; Humans; Hypercholesterolemia; Long-Term Care; Male; Middle Aged; Myocardial Infarction; Pravastatin; Quality of Life; Secondary Prevention; Sensitivity and Specificity	2001
Comparison of low-density lipoprotein cholesterol lowering by pravastatin to <100 mg/dl versus >100 mg/dl on brachial artery vasoreactivity in patients with severe hypercholesterolemia and previous atherosclerotic events or diabetes mellitus. The American journal of cardiology, 2002, Apr-01, Volume: 89, Issue:7 Topics: Adult; Aged; Anticholesteremic Agents; Arteriosclerosis; Brachial Artery; Cholesterol, LDL; Diabetes Complications; Diabetes Mellitus; Drug Administration Schedule; Endothelium, Vascular; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Treatment Outcome; Vasodilation	2002
Importance of NAD(P)H oxidase-mediated oxidative stress and contractile type smooth muscle myosin heavy chain SM2 at the early stage of atherosclerosis. Circulation, 2002, May-14, Volume: 105, Issue:19 Topics: Actins; Animals; Anticholesteremic Agents; Antioxidants; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Diet, Atherogenic; Disease Models, Animal; Elasticity; Hypercholesterolemia; Male; Membrane Transport Proteins; Muscle, Smooth, Vascular; Myosin Heavy Chains; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoproteins; Pravastatin; Probucol; Protein Isoforms; Rabbits; Smooth Muscle Myosins; Superoxides	2002
Safety and tolerability of pravastatin in long-term clinical trials: prospective Pravastatin Pooling (PPP) Project. Circulation, 2002, May-21, Volume: 105, Issue:20 Topics: Aged; Anticholesteremic Agents; Breast Neoplasms; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Cohort Studies; Comorbidity; Demography; Double-Blind Method; Female; Gastrointestinal Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Liver Diseases; Male; Middle Aged; Multivariate Analysis; Muscular Diseases; Pravastatin; Proportional Hazards Models; Prospective Studies; Randomized Controlled Trials as Topic; Renal Insufficiency; Risk; Risk Assessment; Time	2002
Assessment of functional low-density-lipoprotein receptors on lymphocytes by a simplified method using culture medium with lipoprotein-free fetal calf serum and pravastatin. Clinical biochemistry, 1992, Volume: 25, Issue:5 Topics: Adult; Cells, Cultured; Cholesterol; Culture Media; Female; Humans; Hypercholesterolemia; Hyperlipidemias; Lipoproteins, LDL; Lymphocytes; Male; Pravastatin; Receptors, Cell Surface; Receptors, Lipoprotein; Triglycerides	1992
Depressive symptoms in hypercholesterolaemic patients treated with pravastatin. Lancet (London, England), 1992, Oct-10, Volume: 340, Issue:8824 Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Depressive Disorder; Female; Humans; Hypercholesterolemia; Pravastatin; Triglycerides	1992
Subcutaneous administration of HMG-CoA reductase inhibitors in hyperlipidaemic and normal rats. Laboratory animals, 1992, Volume: 26, Issue:4 Topics: Administration, Oral; Animals; Anticholesteremic Agents; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Infusion Pumps, Implantable; Injections, Subcutaneous; Lovastatin; Pravastatin; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Simvastatin	1992
Successful dissolution of cholesterol gallstone during treatment with pravastatin. Gastroenterology, 1992, Volume: 103, Issue:3 Topics: Cholelithiasis; Cholesterol; Humans; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Ultrasonography	1992
Short- and long-term effects of lovastatin and pravastatin alone and in combination with cholestyramine on serum lipids, lipoproteins and apolipoproteins in primary hypercholesterolaemia. European journal of clinical pharmacology, 1992, Volume: 42, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Pravastatin; Time Factors; Triglycerides	1992
Effect of pravastatin on serum lipids, apolipoproteins and lipoprotein (a) in patients with non-insulin dependent diabetes mellitus. Endocrinologia japonica, 1992, Volume: 39, Issue:1 Topics: Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypoglycemic Agents; Lipids; Lipoprotein(a); Lipoproteins; Male; Pravastatin; Triglycerides	1992
Pravastatin reaches U. S. market. Clinical pharmacy, 1992, Volume: 11, Issue:2 Topics: Humans; Hypercholesterolemia; Pravastatin; United States; United States Food and Drug Administration	1992
Cataracts by lipid lowering drugs? Three different HMG-CoA reductase inhibitors studied in hypercholesterolemic rabbits. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1992, Volume: 192, Issue:1 Topics: Animals; Anticholesteremic Agents; Cataract; Cholesterol; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Pravastatin; Rabbits; Simvastatin	1992
Pravastatin, simvastatin, and lovastatin for lowering serum cholesterol concentrations. The Medical letter on drugs and therapeutics, 1992, Jun-12, Volume: 34, Issue:872 Topics: Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin	1992
Hypolipidemic drugs reduce lipoprotein susceptibility to undergo lipid peroxidation: in vitro and ex vivo studies. Atherosclerosis, 1992, Volume: 93, Issue:1-2 Topics: Adult; Animals; Bezafibrate; Cells, Cultured; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Esterification; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Male; Malondialdehyde; Mice; Middle Aged; Pravastatin; Vitamin E	1992
The effects of pravastatin on hyperlipidemia in renal transplant recipients. Transplantation, 1992, Volume: 53, Issue:1 Topics: Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cyclosporine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Transplantation; Postoperative Complications; Pravastatin; Triglycerides	1992
Serum Lp(a) concentrations are unaffected by treatment with the HMG-CoA reductase inhibitor Pravastatin: results of a 2-year investigation. Clinica chimica acta; international journal of clinical chemistry, 1991, Dec-31, Volume: 204, Issue:1-3 Topics: Adult; Aged; Apolipoprotein B-100; Apolipoproteins B; C-Reactive Protein; Cholesterol; Cholesterol, LDL; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein(a); Lipoproteins; Male; Middle Aged; Pravastatin; Triglycerides	1991
Pravastatin and simvastatin for hypercholesterolemia. The Medical letter on drugs and therapeutics, 1991, Mar-08, Volume: 33, Issue:839 Topics: Anticholesteremic Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Therapy, Combination; Heptanoic Acids; Humans; Hypercholesterolemia; Lovastatin; Muscular Diseases; Naphthalenes; Pravastatin; Simvastatin	1991
The effect of pravastatin on serum cholesterol levels in hypercholesterolemic diabetic rabbits. Biochimica et biophysica acta, 1991, Apr-15, Volume: 1096, Issue:3 Topics: Animals; Anticholesteremic Agents; Apolipoproteins; Body Weight; Cholesterol; Coconut Oil; Diabetes Complications; Diabetes Mellitus; Diet, Atherogenic; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Male; Naphthalenes; Plant Oils; Pravastatin; Rabbits; Triglycerides	1991
Hypercholesterolaemia: simvastatin and pravastatin alter cholesterol metabolism by different mechanisms. Biochimica et biophysica acta, 1991, Apr-03, Volume: 1082, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Hypercholesterolemia; Leukocytes; Lovastatin; Middle Aged; Naphthalenes; Pravastatin; Simvastatin	1991
Comparison of different HMG-CoA reductase inhibitors. European journal of clinical pharmacology, 1991, Volume: 40 Suppl 1 Topics: Anticholesteremic Agents; Apolipoproteins; Cholesterol, HDL; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Naphthalenes; Pravastatin; Simvastatin; Triglycerides	1991
Pravastatin (Lipostat)--another statin for lowering cholesterol. Drug and therapeutics bulletin, 1991, Jun-10, Volume: 29, Issue:12 Topics: Humans; Hypercholesterolemia; Pravastatin	1991
Comparative effects of simvastatin (MK-733) and pravastatin (CS-514) on hypercholesterolemia induced by cholesterol feeding in rabbits. Biochimica et biophysica acta, 1990, Feb-23, Volume: 1042, Issue:3 Topics: Animals; Bile; Cholesterol; Cholesterol, Dietary; Heptanoic Acids; Hypercholesterolemia; Lipoproteins; Lipoproteins, LDL; Lovastatin; Male; Microsomes, Liver; Naphthalenes; Pravastatin; Rabbits; Receptors, LDL; Simvastatin; Statistics as Topic; Sterol O-Acyltransferase	1990
Effect of pravastatin, an HMG CoA reductase inhibitor, and cholestyramine, a bile acid sequestrant, on lipoprotein particles defined by their apolipoprotein composition. Metabolism: clinical and experimental, 1990, Volume: 39, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoprotein C-III; Apolipoproteins; Apolipoproteins A; Apolipoproteins B; Apolipoproteins C; Apolipoproteins E; Bile Acids and Salts; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cholestyramine Resin; Drug Evaluation; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipid Metabolism; Lipoproteins; Male; Middle Aged; Naphthalenes; Pravastatin; Random Allocation; Triglycerides	1990
[Evaluation of the efficacy and safety of pravastatin in primary hypercholesterolemia]. Bollettino chimico farmaceutico, 1990, Volume: 129, Issue:6 Topics: Anticholesteremic Agents; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Naphthalenes; Pravastatin	1990
Pravastatin--ocular side effects after a two year follow-up? Lens and eye toxicity research, 1990, Volume: 7, Issue:3-4 Topics: Aged; Anticholesteremic Agents; Cataract; Cholesterol, LDL; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Lens, Crystalline; Longitudinal Studies; Male; Middle Aged; Naphthalenes; Pravastatin; Triglycerides	1990
Ocular drug-safety study with the HMG-CoA reductase inhibitor pravastatin. Lens and eye toxicity research, 1990, Volume: 7, Issue:3-4 Topics: Anterior Eye Segment; Cataract; Densitometry; Drug Evaluation; Eyelids; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Image Processing, Computer-Assisted; Intraocular Pressure; Lens, Crystalline; Male; Naphthalenes; Photography; Pravastatin; Visual Acuity	1990
Long-term treatment of hypercholesterolemic non-insulin dependent diabetics (NIDDM) with pravastatin (CS-514). Atherosclerosis, 1989, Volume: 75, Issue:1 Topics: Adult; Anticholesteremic Agents; Apolipoproteins; Blood Glucose; Diabetes Mellitus, Type 2; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipoproteins; Male; Middle Aged; Naphthalenes; Pravastatin; Time Factors	1989
Probucol versus eptastatin in hypercholesterolaemic diabetics. Lancet (London, England), 1986, Sep-27, Volume: 2, Issue:8509 Topics: Cholesterol, HDL; Diabetes Complications; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Naphthalenes; Phenols; Pravastatin; Probucol	1986
Effect of CS-514, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on lipoprotein and apolipoprotein in plasma of hypercholesterolemic diabetics. Diabetes research and clinical practice, 1986, Volume: 2, Issue:3 Topics: Apolipoproteins; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Diabetes Complications; Diabetes Mellitus; Glycated Hemoglobin; Heptanoic Acids; Humans; Hypercholesterolemia; Lipoproteins; Naphthalenes; Pravastatin	1986
Treating hyperlipidemia, Part III: Drug therapy. Geriatrics, 1987, Volume: 42, Issue:8 Topics: Aged; Enzyme Inhibitors; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Naphthalenes; Neomycin; Niacin; Pentanoic Acids; Pravastatin	1987