pravastatin has been researched along with Fibrosis in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Gari, M; Kumar Mariappan, A; Kumar, A; Kumar, D; Kumar, T; Lingaraju, MC; Parida, S; Rana, A; Sharma, M; Singh, TU | 1 |
| Brunner, TB | 1 |
| Auperin, A; Azria, D; Boisselier, P; Bourgier, C; Bourhis, J; Deutsch, E; Lang, P; Lassau, N; Petit, B; Rivera, S; Taourel, P; Tetreau, R; Vozenin, MC | 1 |
| Fukumoto, Y; Kudo, S; Liao, JK; Minami, T; Nochioka, K; Shiba, N; Shimokawa, H; Takai, Y; Tanaka, S; Williams, CL | 1 |
| Ikeda, S; Kikuchi, N; Kudo, S; Kurosawa, R; Minami, T; Miyata, S; Nogi, M; Omura, J; Satoh, K; Satoh, T; Shimokawa, H; Sunamura, S; Suzuki, K | 1 |
| Asakura, M; Asano, Y; Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Liao, Y; Minamino, T; Takashima, S; Zhao, H | 1 |
| Harada, M; Otani, M; Otsuki, M; Yamamoto, M | 1 |
| Harada, M; Otsuki, M; Wei, L; Yamamoto, M | 1 |
| Fukui, K; Hibi, K; Kunishima, T; Michishita, I; Nozue, T; Onishi, Y; Terashima, M; Tohyama, S; Umezawa, S; Yamamoto, S | 1 |
| Alhaj, MA; Elnakish, MT; Hassanain, HH; Hassona, MD; Janssen, PM; Khan, M; Moldovan, L | 1 |
| Bang, BK; Jung, JY; Kim, J; Kim, SB; Kim, YS; Li, C; Lim, SW; Park, JH; Sun, BK; Yang, CW | 1 |
| Cha, JH; Kang, DH; Kang, SW; Kim, J; Kim, YS; Li, C; Lim, SW; Song, JC; Sun, BK; Yang, CW | 1 |
| Abe, Y; Ikewaki, K; Izumi, T; Mochizuki, S; Nagai, M; Taniguchi, I; Urabe, A | 1 |
| Aigueperse, J; Bourgier, C; Bourhis, J; François, A; Gilliot, O; Haydont, V; Rivera, S; Vozenin-Brotons, MC | 1 |
| Aigueperse, J; Bourgier, C; Bourhis, J; Haydont, V; Lusinchi, A; Mathé, D; Pocard, M; Vozenin-Brotons, MC | 1 |
| Akino, M; Matsui, Y; Okamoto, H; Onozuka, H; Tsutsui, H; Xu, Z | 1 |
| Ando, A; Hori, M; Horio, M; Imai, E; Kawada, N; Moriyama, T; Nagatoya, K; Takeji, M | 1 |
3 trial(s) available for pravastatin and Fibrosis
| Article | Year |
|---|---|
Pravastatin Reverses Established Radiation-Induced Cutaneous and Subcutaneous Fibrosis in Patients With Head and Neck Cancer: Results of the Biology-Driven Phase 2 Clinical Trial Pravacur.
Topics: Confidence Intervals; Dermatologic Agents; Fibrosis; Head and Neck Neoplasms; Humans; Pravastatin; Prospective Studies; Quality of Life; Radiation Injuries; Skin; Squamous Cell Carcinoma of Head and Neck | 2019 |
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Atorvastatin; Biomarkers; Cardiomegaly; Cells, Cultured; Cholesterol; Cholesterol, LDL; Coronary Vessels; Cross-Over Studies; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanine Nucleotide Exchange Factors; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Male; Mice; Mice, Knockout; Neuropeptides; Oxidative Stress; Phosphatidylinositol 3-Kinase; Pravastatin; Proto-Oncogene Proteins c-akt; Pyrroles; Quinolines; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; RNA Interference; Signal Transduction; Transfection | 2013 |
Impacts of estimated glomerular filtration rate on coronary atherosclerosis and plaque composition before and during statin therapy in patients with normal to mild renal dysfunction: subanalysis of the TRUTH study.
Topics: Aged; Biomarkers; Coronary Artery Disease; Coronary Vessels; Dyslipidemias; Female; Fibrosis; Glomerular Filtration Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Kidney; Kidney Diseases; Lipids; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Plaque, Atherosclerotic; Pravastatin; Prospective Studies; Quinolines; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome; Ultrasonography, Interventional | 2012 |
14 other study(ies) available for pravastatin and Fibrosis
| Article | Year |
|---|---|
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model.
Topics: Animals; Body Weight; Collagen; Fibrosis; Isoproterenol; Mice; Pravastatin; Transforming Growth Factor beta | 2023 |
[Pravastatin is capable to reduce radiation induced fibrosis after head-and-neck treatment].
Topics: Fibrosis; Head and Neck Neoplasms; Humans; Pravastatin; Radiation Pneumonitis; Skin | 2020 |
SmgGDS as a Crucial Mediator of the Inhibitory Effects of Statins on Cardiac Hypertrophy and Fibrosis: Novel Mechanism of the Pleiotropic Effects of Statins.
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cardiomegaly; Cell Proliferation; Cells, Cultured; Chemokines; Cytoskeletal Proteins; Disease Models, Animal; Fibrosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Myocytes, Cardiac; Pravastatin; Random Allocation; Rats; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Role; Species Specificity | 2016 |
Inhibition of cardiac remodeling by pravastatin is associated with amelioration of endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Cardiomegaly; Endoplasmic Reticulum; Fibrosis; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Molecular Chaperones; Myocardium; Myocytes, Cardiac; Pravastatin; Signal Transduction; Stress, Physiological; Tumor Necrosis Factor-alpha; Ventricular Pressure; Ventricular Remodeling | 2008 |
Effect of long- and short-term treatments with pravastatin on diabetes mellitus and pancreatic fibrosis in the Otsuka-Long-Evans-Tokushima fatty rat.
Topics: Adipose Tissue, White; Animals; Apoptosis; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Fibrosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Resistance; Male; Organ Size; Pancreas; Peroxidase; Pravastatin; Rats; Rats, Long-Evans; Superoxide Dismutase; Time Factors; Transforming Growth Factor beta1; Triglycerides; Tumor Necrosis Factor-alpha | 2010 |
Treatment with pravastatin attenuates progression of chronic pancreatitis in rat.
Topics: Analysis of Variance; Animals; Fibrosis; Hydroxyproline; Immunohistochemistry; Interleukin-10; Male; Pancreatitis, Chronic; Pravastatin; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2011 |
Rac-induced left ventricular dilation in thyroxin-treated ZmRacD transgenic mice: role of cardiomyocyte apoptosis and myocardial fibrosis.
Topics: Animals; Apoptosis; Blotting, Western; Carbazoles; Cardiomegaly; Cardiomyopathies; Carvedilol; Echocardiography; Female; Fibrosis; Male; Mice; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Pravastatin; Propanolamines; rac GTP-Binding Proteins; Thyroxine; Vasodilator Agents | 2012 |
Pravastatin treatment attenuates interstitial inflammation and fibrosis in a rat model of chronic cyclosporine-induced nephropathy.
Topics: Animals; Anticholesteremic Agents; C-Reactive Protein; Cyclosporine; Fibrosis; Immunosuppressive Agents; Inflammation Mediators; Kidney; Macrophages; Male; Nephritis; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Osteopontin; Pravastatin; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Combined effects of losartan and pravastatin on interstitial inflammation and fibrosis in chronic cyclosporine-induced nephropathy.
Topics: Animals; C-Reactive Protein; Cyclosporine; Disease Models, Animal; Fibrosis; Inflammation; Kidney; Kidney Diseases; Losartan; Male; Pravastatin; Rats; Rats, Sprague-Dawley | 2005 |
Pravastatin prevents myocardium from ischemia-induced fibrosis by protecting vascular endothelial cells exposed to oxidative stress.
Topics: Animals; Anticholesteremic Agents; Apoptosis; Caspase 3; Cell Line; Endothelial Cells; Endothelium, Vascular; Fibrosis; Heart; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Contraction; Myocardial Infarction; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Pravastatin; Rats; Rats, Wistar | 2006 |
Successful mitigation of delayed intestinal radiation injury using pravastatin is not associated with acute injury improvement or tumor protection.
Topics: Animals; Apoptosis; Cell Line, Tumor; Collagen; Connective Tissue Growth Factor; Drug Evaluation, Preclinical; Female; Fibrosis; HeLa Cells; HT29 Cells; Humans; Ileum; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Nude; Pravastatin; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Rats, Wistar | 2007 |
Pravastatin Inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats.
Topics: Animals; Connective Tissue Growth Factor; Extracellular Matrix; Fibrosis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Intestinal Diseases; Intestines; Male; Pravastatin; Radiation Injuries; Rats; Rats, Wistar; rho GTP-Binding Proteins; rho-Associated Kinases | 2007 |
Pravastatin attenuates left ventricular remodeling and diastolic dysfunction in angiotensin II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cholesterol; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart Failure, Diastolic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Pravastatin; rho-Associated Kinases; Ventricular Remodeling | 2008 |
Fluvastatin suppresses oxidative stress and fibrosis in the interstitium of mouse kidneys with unilateral ureteral obstruction.
Topics: Actins; Animals; Cholesterol; Disease Models, Animal; Fatty Acids, Monounsaturated; Fibrosis; Fluvastatin; Gene Expression; Glycation End Products, Advanced; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Kidney; Membrane Proteins; Mice; Nephritis, Interstitial; Oxidative Stress; Pravastatin; RNA, Messenger; Triglycerides; Ureteral Obstruction | 2001 |