Page last updated: 2024-08-23

pravastatin and Disease Exacerbation

pravastatin has been researched along with Disease Exacerbation in 80 studies

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's21 (26.25)18.2507
2000's39 (48.75)29.6817
2010's19 (23.75)24.3611
2020's1 (1.25)2.80

Authors

AuthorsStudies
Andia, ME; Botnar, RM; Lavin Plaza, B; Lorrio, S; Phinikaridou, A; Potter, M; Rashid, I1
Jeon, Y; Kim, S; Lee, JH; Min, JJ; Ryu, DK; Shin, BS; Shin, YH1
Clifton, J; Lang, T; Neher, J; Safranek, S1
Daida, H; Hata, M; Kaku, K; Kawamori, R; Kishimoto, J; Kurabayashi, M; Masuda, I; Nohara, R; Sakuma, I; Yamazaki, T; Yokoi, H; Yoshida, M3
Lee, CW; Park, SJ1
Chertow, GM; Erickson, KF; Garber, AM; Goldhaber-Fiebert, JD; Japa, S; Owens, DK1
Barnes, EH; Blankenberg, S; Colquhoun, DM; Fournier, M; Nestel, PJ; Simes, J; Sullivan, DR; Tonkin, AM; White, HD1
Cadnapaphornchai, MA1
Bissler, JJ1
Carter, D; Chandraker, A; Gabardi, S; Kim, M; Klasek, R; Mackenzie, MR; Ramasamy, S; Tan, CS1
Brower, V1
Brener, SJ; Hu, T; Ivanc, TB1
Baimbridge, C; Barzilay, J; Basile, JN; Davis, BR; Henriquez, MA; Huml, A; Kopyt, N; Louis, GT; Pressel, SL; Rahman, M; Rosendorff, C; Sastrasinh, S; Stanford, C1
Tonelli, M1
Coombes, JS; Fairley, KF; Fassett, RG; Kincaid-Smith, P; Packham, D1
de Vries, JP; Hoefer, IE; Hurks, R; Kerver, M; Moll, FL; Pasterkamp, G; Schoneveld, A; Tangelder, MJ; Vink, A1
Strandberg, TE1
Alipour, A; Cabezas, MC; Defesche, JC; Elte, JW; Jukema, JW; Ribalta, J; Vallvé, JC; Zwinderman, AH1
Cadnapaphornchai, MA; George, DM; Masoumi, A; McFann, K; Schrier, RW; Strain, JD1
Hirayama, A; Nagao, K; Tani, S1
Fukui, K; Hibi, K; Kunishima, T; Michishita, I; Miyake, S; Morino, Y; Muramatsu, T; Nozato, T; Nozue, T; Onishi, Y; Sato, A; Takeyama, Y; Terashima, M; Tohyama, S; Umezawa, S; Yamamoto, S; Yamauchi, T1
Shah, PK1
Ako, JY; Daida, H; Eto, M; Kurata, T; Mokuno, H; Nishide, T; Ouchi, Y; Saito, Y; Sato, H; Tango, T; Yamada, N; Yamaguchi, H1
Kerensky, RA; Monroe, VS; Pepine, CJ; Rivera, E; Smith, KM1
Agema, WR; Boekholdt, SM; Jukema, JW; Kastelein, JJ; Peters, RJ; Reitsma, PH; van der Wall, EE; Zwinderman, AH1
Hayashi, J; Kikuchi, K; Maeda, N; Okada, K; Sawayama, Y; Shimizu, C; Tatsukawa, M1
Kröger, K; Wittlinger, T1
Brodie, B; Brown, BG; Cooper, CJ; Crowe, T; DeMaria, AN; Ganz, P; Grines, CL; Howard, G; Nissen, SE; Schoenhagen, P; Tuzcu, EM; Vogel, RA1
Agema, WR; Boer, JM; de Maat, MP; Feskens, EJ; Jukema, JW; Kastelein, JJ; Rabelink, TJ; van Boven, AJ; van der Wall, EE; Zwinderman, AH1
Cressman, MD; Harris, S; Hutchinson, HG; Pears, JS; Vidt, DG1
Agema, WR; de Maat, MP; Kastelein, JJ; Rabelink, TJ; van der Wall, EE; Wouter Jukema, J; Zwinderman, AH1
Baggio, G; Bond, MG; Crepaldi, G; Gallus, G; Magni, A; Mancia, G; Rubba, P; Sampieri, L; Sperti, G; Veglia, F; Ventura, A; Zanchetti, A1
Kurachi, O; Maruo, T; Matsuo, H; Nakago, S; Oki, N; Takeuchi, K; Yamanaka, Y1
Adams, GJ; Ballantyne, CM; Greene, J; Harrist, R; Insull, W; Karmonik, C; Kimball, KT; Morrisett, JD; Vick, GW1
Crowe, T; Ganz, P; Magorien, RD; Nissen, SE; O'Shaughnessy, C; Orazem, J; Sasiela, WJ; Schoenhagen, P; Tsai, J; Tuzcu, EM1
Blauw, GJ; Bollen, EL; de Craen, AJ; Ford, I; ten Dam, VH; van Buchem, MA; van den Heuvel, DM; Westendorp, RG1
Daida, H; Endo, M; Furuse, A; Hosoda, S; Hosoda, Y; Makuuchi, H; Nakamura, H; Ohashi, Y; Watanabe, M; Yamaguchi, H; Yasui, H1
Curhan, G; Jhangri, GS; Pfeffer, M; Sacks, F; Tonelli, M1
Ichihara, G; Ichihara, S; Kawanishi, S; Nagata, K; Noda, A; Obata, K; Oikawa, S; Xu, J; Yamada, Y; Yokota, M1
Admiraal-Behloul, F; Blauw, GJ; Bollen, EL; de Craen, AJ; Jolles, J; Murray, HM; Olofsen, H; ten Dam, VH; van Buchem, MA; van den Heuvel, DM; Westendorp, RG1
Chen, MS; Crowe, T; Kapadia, S; Loyd, AB; Nicholls, SJ; Nissen, SE; Schoenhagen, P; Sipahi, I; Tuzcu, EM1
Hazen, SL; Nicholls, SJ; Nissen, SE; Ntanios, F; Schoenhagen, P; Sipahi, I; Tuzcu, EM; Wun, CC1
Bardou, M; Dumas, M; Goirand, F; Guerard, P; Lirussi, F; Rakotoniaina, Z; Rochette, L1
Furusyo, N; Hayashi, J; Maeda, S; Ohnishi, H; Okada, K; Sawayama, Y1
Watson, KE1
Rouhiainen, H; Rouhiainen, P; Salonen, JT1
Bruin, T; Bruschke, AV; Gagné, E; Groenemeijer, B; Hayden, MR; Henneman, JA; Jansen, H; Jukema, JW; Kastelein, JJ; Molhoek, GP; Reiber, JH; van Boven, AJ; Zwinderman, AH1
Bianchi, G; Bond, MG; Crepaldi, G; D'Alò, G; Descovich, G; Feruglio, FS; Gallus, G; Mancini, M; Mercuri, M; Ricci, G; Rubba, P; Sirtori, CR; Veglia, F; Ventura, A1
Angelin, B; Juliusson, G; Vitols, S1
Mikuriya, Y; Nasu, M; Tamura, A1
Akasaka, T; Hozumi, T; Morioka, S; Takagi, T; Yoshida, K; Yoshikawa, J1
Bassand, JP; Bertrand, ME; Cassagnes, J; Castaigne, A; Commeau, P; Danchin, N; Fruchart, JC; Grollier, G; Lablanche, JM; Machecourt, J; McFadden, EP; Mossard, JM; Vacheron, A; Van Belle, E1
Bruschke, AV; Cobbaert, C; Jukema, JW; Lindemans, J; Withagen, AJ; Zwinderman, AH1
Bruschke, AV; de Knijff, P; Jukema, JW; Kastelein, JJ; Kuivenhoven, JA; Lie, KI; McPherson, R; Zwinderman, AH1
Chia, D; Hirata, M; Katznelson, S; Kobashigawa, JA; Ozawa, M; Terasaki, PI; Wang, XM; Zhong, HP1
Gamble, G; Hart, H; MacMahon, S; Scott, J; Sharpe, N; Simes, J; White, H1
Goldstein, MR1
Dullaart, RP; van Tol, A1
Ackerstaff, RG; Bom, N; Bruschke, AV; de Groot, E; Jukema, JW; Lie, KI; Montauban van Swijndregt, AD; van der Steen, AF; Zwinderman, AH1
Bruschke, AV; Jukema, JW; van Boven, AJ; Van der Laarse, A; Zwinderman, AH1
Albarrán, OG; García-Robles, R; Rábano, A; Ruilope, LM; Villa, E1
Pitt, B1
Azuma, N; Matsugane, T; Motohashi, K; Nishide, T; Nobuto, T; Suzuki, M; Yamane, S1
Braunwald, E; Davis, BR; Flaker, GC; Moyé, LA; Pfeffer, MA; Rouleau, JL; Sacks, FM; Warnica, JW; Webel, RR1
Cao, Z; Cooper, ME; Cox, AJ; Gilbert, RE; Jandeleit-Dahm, K; Kelly, DJ1
Pedersen, TR1
Bandoh, T; Hayashi, S; Ishikawa, J; Kimura, M; Kusumi, Y; Mitani, H; Niihashi, M; Sakurai, I; Totsuka, T1
Baldassarre, D; Bong, MG; Collatina, S; Crepaldi, G; Fisicaro, M; Gallus, G; Gobbi, C; Mancini, M; Ricci, G; Rimondi, S; Sirtori, CR; Veglia, F; Ventura, A1
Brown, WV1
Su, DH; Yeo, KT1
Crisby, M; Nilsson, J; Nordin-Fredriksson, G; Shah, PK; Yano, J; Zhu, J1
Baggio, G; Bond, MG; Collatina, S; Crepaldi, G; Gallus, GV; Mancia, G; Rubba, P; Sampieri, L; Serrotti, E; Veglia, F; Ventura, A; Zanchetti, A1
Bachmann, GA; Callister, TQ; Davidson, M; Kafonek, S; Laskey, R; Pittman, D; Raggi, P; Scott, R; Welty, FK1
Griffin, BP; Lauer, MS; Novaro, GM; Pearce, GL; Sprecher, DL; Tiong, IY1
Bru, C; Campistol, JM; Cofan, F; Cofan, M; Gilabert, R; Nunez, I; Oppenheimer, F; Ros, E; Zambon, D1
Freedman, DS; Otvos, JD; Rosenson, RS1

Reviews

12 review(s) available for pravastatin and Disease Exacerbation

ArticleYear
Cost-effectiveness of statins for primary cardiovascular prevention in chronic kidney disease.
    Journal of the American College of Cardiology, 2013, Mar-26, Volume: 61, Issue:12

    Topics: Aged; Cost-Benefit Analysis; Decision Support Techniques; Disease Progression; Drug Costs; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Kidney Failure, Chronic; Male; Markov Chains; Myocardial Infarction; Pravastatin; Primary Prevention; Quality-Adjusted Life Years; Rhabdomyolysis; Risk; Sex Factors; Stroke; United States

2013
Autosomal dominant polycystic kidney disease in children.
    Current opinion in pediatrics, 2015, Volume: 27, Issue:2

    Topics: Blood Pressure; Child; Child, Preschool; Diet, Sodium-Restricted; Disease Progression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Polycystic Kidney, Autosomal Dominant; Pravastatin; Prognosis; Renal Dialysis; Ultrasonography

2015
Therapies for polycystic kidney disease.
    Current opinion in pediatrics, 2015, Volume: 27, Issue:2

    Topics: Diet, Sodium-Restricted; Directive Counseling; Disease Progression; Exercise; Fruit; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Polycystic Kidney Diseases; Pravastatin; Prognosis; Renin-Angiotensin System; Risk Reduction Behavior; Vegetables

2015
Lipid-lowering drugs and heart failure: where do we go after the statin trials?
    Current opinion in cardiology, 2010, Volume: 25, Issue:4

    Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Pravastatin; Primary Prevention; Prognosis; Pyrroles; Risk Factors; Secondary Prevention; Triglycerides

2010
Pharmacologic plaque passivation for the reduction of recurrent cardiac events in acute coronary syndromes.
    Journal of the American College of Cardiology, 2003, Feb-19, Volume: 41, Issue:4 Suppl S

    Topics: Abciximab; Acute Disease; Angina, Unstable; Antibodies, Monoclonal; C-Reactive Protein; Coronary Artery Disease; Coronary Thrombosis; Disease Progression; Endothelium, Vascular; Enoxaparin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin Fab Fragments; Macrophages; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pravastatin; Randomized Controlled Trials as Topic; Secondary Prevention; Severity of Illness Index

2003
[Role of lipid lowering therapy in patients with peripheral arterial occlusive disease].
    Herz, 2004, Volume: 29, Issue:1

    Topics: Anticholesteremic Agents; Arterial Occlusive Diseases; Atorvastatin; Disease Progression; Exercise Test; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Jejunoileal Bypass; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome

2004
Rosuvastatin-induced arrest in progression of renal disease.
    Cardiology, 2004, Volume: 102, Issue:1

    Topics: Aged; Atorvastatin; Controlled Clinical Trials as Topic; Creatine; Disease Progression; Drug Administration Schedule; Female; Fluorobenzenes; Glomerular Filtration Rate; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Kidney; Kidney Diseases; Male; Middle Aged; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2004
What is the evidence in favor of low-dose statin therapy in 2008?
    Current atherosclerosis reports, 2008, Volume: 10, Issue:1

    Topics: Cardiovascular Diseases; Disease Progression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pravastatin; Risk Assessment; Simvastatin; Treatment Outcome

2008
Results of recent trials on the progression of coronary artery disease and recurrent ischemic events: implications for interventional cardiology.
    Journal of interventional cardiology, 1994, Volume: 7, Issue:6

    Topics: alpha-Linolenic Acid; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Diet Therapy; Disease Progression; Humans; Myocardial Ischemia; Pravastatin

1994
Role of hyperlipidemia in progressive renal disease: focus on diabetic nephropathy.
    Kidney international. Supplement, 1999, Volume: 71

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Clinical Trials as Topic; Diabetic Nephropathies; Disease Progression; Gene Expression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; In Situ Hybridization; Kidney Diseases; Kidney Glomerulus; Lovastatin; Male; Nephrectomy; Pravastatin; Pyrroles; Rats; Rats, Sprague-Dawley; Simvastatin; Transforming Growth Factor beta

1999
Statin trials and goals of cholesterol-lowering therapy after AMI.
    American heart journal, 1999, Volume: 138, Issue:2 Pt 2

    Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Artery Disease; Coronary Disease; Disease Progression; Europe; Humans; Myocardial Infarction; Myocardial Ischemia; Pravastatin; Prospective Studies; Randomized Controlled Trials as Topic; Scandinavian and Nordic Countries; Simvastatin; Survival Rate; United States

1999
Cholesterol lowering in atherosclerosis.
    The American journal of cardiology, 2000, Aug-24, Volume: 86, Issue:4B

    Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Coronary Artery Disease; Disease Progression; Heptanoic Acids; Humans; Pravastatin; Pyrroles; Simvastatin

2000

Trials

45 trial(s) available for pravastatin and Disease Exacerbation

ArticleYear
Intensive lipid-lowering therapy for slowing progression as well as inducing regression of atherosclerosis in Japanese patients: subanalysis of the JART study.
    International heart journal, 2013, Volume: 54, Issue:1

    Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Carotid Intima-Media Thickness; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; Female; Fluorobenzenes; Humans; Hypercholesterolemia; Japan; Lipid Metabolism; Male; Middle Aged; Outcome Assessment, Health Care; Pharmacovigilance; Pravastatin; Preventive Health Services; Pyrimidines; Risk Assessment; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome

2013
Plasma lipoprotein(a) concentration predicts future coronary and cardiovascular events in patients with stable coronary heart disease.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:12

    Topics: Aged; Angina, Unstable; Australia; Biomarkers; Coronary Disease; Disease Progression; Disease-Free Survival; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoprotein(a); Male; Middle Aged; Myocardial Infarction; New Zealand; Pravastatin; Predictive Value of Tests; Proportional Hazards Models; Risk Assessment; Risk Factors; Time Factors; Up-Regulation

2013
Change in carotid intima-media thickness in a high-risk group of patients by intensive lipid-lowering therapy with rosuvastatin: subanalysis of the JART study.
    International heart journal, 2014, Volume: 55, Issue:2

    Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Carotid Intima-Media Thickness; Cholesterol, LDL; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fluorobenzenes; Follow-Up Studies; Humans; Lipids; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrimidines; Risk Factors; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome

2014
Progression of kidney disease in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin versus usual care: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 52, Issue:3

    Topics: Aged; Anticholesteremic Agents; Cholesterol; Disease Progression; Female; Glomerular Filtration Rate; Humans; Hypercholesterolemia; Hypertension; Incidence; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged; Pravastatin; Treatment Outcome

2008
Effect of pravastatin on kidney function and urinary protein excretion in autosomal dominant polycystic kidney disease.
    Scandinavian journal of urology and nephrology, 2010, Volume: 44, Issue:1

    Topics: Disease Progression; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Male; Middle Aged; Polycystic Kidney, Autosomal Dominant; Pravastatin; Prospective Studies; Proteinuria

2010
Effect of statin therapy on disease progression in pediatric ADPKD: design and baseline characteristics of participants.
    Contemporary clinical trials, 2011, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Child; Disease Progression; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Kidney; Lisinopril; Male; Polycystic Kidney, Autosomal Dominant; Pravastatin; Renin-Angiotensin System; Young Adult

2011
Effect of intensive lipid-lowering therapy with rosuvastatin on progression of carotid intima-media thickness in Japanese patients: Justification for Atherosclerosis Regression Treatment (JART) study.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:1

    Topics: Aged; Asian People; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; Female; Fluorobenzenes; Humans; Hypercholesterolemia; Hypolipidemic Agents; Japan; Longitudinal Studies; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrimidines; Rosuvastatin Calcium; Single-Blind Method; Sulfonamides; Time Factors; Treatment Outcome

2012
Effects of serum n-3 to n-6 polyunsaturated fatty acids ratios on coronary atherosclerosis in statin-treated patients with coronary artery disease.
    The American journal of cardiology, 2013, Jan-01, Volume: 111, Issue:1

    Topics: Aged; Biomarkers; Chromatography, Gas; Coronary Artery Disease; Coronary Vessels; Disease Progression; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pravastatin; Prospective Studies; Quinolines; Treatment Outcome; Ultrasonography, Interventional

2013
Preventing angiographic progression of coronary atherosclerosis with pravastatin.
    Journal of atherosclerosis and thrombosis, 2003, Volume: 10, Issue:1

    Topics: Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Disease Progression; Endpoint Determination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Middle Aged; Pravastatin; Prospective Studies; Regression Analysis; Risk Factors; Treatment Outcome

2003
Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events.
    Circulation, 2003, May-20, Volume: 107, Issue:19

    Topics: Amino Acid Substitution; Cohort Studies; Coronary Artery Disease; Disease Progression; Disease-Free Survival; Drosophila Proteins; Gene Frequency; Genetic Carrier Screening; Genetic Predisposition to Disease; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Membrane Glycoproteins; Multicenter Studies as Topic; Polymorphism, Genetic; Pravastatin; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Cell Surface; Risk Assessment; Toll-Like Receptor 4; Toll-Like Receptors; Treatment Outcome

2003
Association of Chlamydia pneumoniae antibody with the cholesterol-lowering effect of statins.
    Atherosclerosis, 2003, Volume: 171, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angiography; Antibodies, Bacterial; Blotting, Western; Carotid Artery Diseases; Chlamydophila Infections; Chlamydophila pneumoniae; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin A; Immunoglobulin G; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Probucol; Risk Assessment; Severity of Illness Index; Treatment Outcome

2003
Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial.
    JAMA, 2004, Mar-03, Volume: 291, Issue:9

    Topics: Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Coronary Vessels; Disease Progression; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Function Tests; Male; Middle Aged; Observer Variation; Pravastatin; Pyrroles; Ultrasonography, Interventional

2004
An integrated evaluation of endothelial constitutive nitric oxide synthase polymorphisms and coronary artery disease in men.
    Clinical science (London, England : 1979), 2004, Volume: 107, Issue:3

    Topics: Anticholesteremic Agents; Case-Control Studies; Coronary Angiography; Coronary Disease; Disease Progression; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Pravastatin; Statistics, Nonparametric

2004
Pharmacogenetics of the CD14 endotoxin receptor polymorphism and progression of coronary atherosclerosis.
    Thrombosis and haemostasis, 2004, Volume: 91, Issue:5

    Topics: Coronary Artery Disease; Disease Progression; Drug Resistance; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipopolysaccharide Receptors; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Pravastatin; Promoter Regions, Genetic; Receptors, Immunologic

2004
Different effects of antihypertensive regimens based on fosinopril or hydrochlorothiazide with or without lipid lowering by pravastatin on progression of asymptomatic carotid atherosclerosis: principal results of PHYLLIS--a randomized double-blind trial.
    Stroke, 2004, Volume: 35, Issue:12

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Antihypertensive Agents; Carotid Stenosis; Disease Progression; Diuretics; Drug Therapy, Combination; Female; Fosinopril; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Pravastatin; Sodium Chloride Symporter Inhibitors

2004
Effects of combined estriol/pravastatin therapy on intima-media thickness of common carotid artery in hyperlipidemic postmenopausal women.
    Gynecologic and obstetric investigation, 2005, Volume: 59, Issue:2

    Topics: Arteriosclerosis; Carotid Artery, Common; Disease Progression; Drug Therapy, Combination; Estriol; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Postmenopause; Pravastatin; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography

2005
Tracking regression and progression of atherosclerosis in human carotid arteries using high-resolution magnetic resonance imaging.
    Magnetic resonance imaging, 2004, Volume: 22, Issue:9

    Topics: Aged; Aged, 80 and over; Algorithms; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Carotid Arteries; Carotid Artery Diseases; Disease Progression; Female; Follow-Up Studies; Heptanoic Acids; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Middle Aged; Observer Variation; Pilot Projects; Pravastatin; Pyrroles; Reproducibility of Results; Simvastatin

2004
Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease.
    The New England journal of medicine, 2005, Jan-06, Volume: 352, Issue:1

    Topics: Anticholesteremic Agents; Atorvastatin; Biomarkers; C-Reactive Protein; Cholesterol, LDL; Coronary Artery Disease; Coronary Vessels; Disease Progression; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Middle Aged; Myocardial Infarction; Pravastatin; Pyrroles; Regression Analysis; Risk Factors; Secondary Prevention; Ultrasonography, Interventional

2005
Effect of pravastatin on cerebral infarcts and white matter lesions.
    Neurology, 2005, May-24, Volume: 64, Issue:10

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Cerebral Infarction; Cholesterol, LDL; Disease Progression; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Arteriosclerosis; Magnetic Resonance Imaging; Male; Nerve Fibers, Myelinated; Pravastatin; Prospective Studies; Telencephalon; Treatment Failure

2005
Effect of pravastatin on progression of coronary atherosclerosis in patients after coronary artery bypass surgery.
    Circulation journal : official journal of the Japanese Circulation Society, 2005, Volume: 69, Issue:6

    Topics: Aged; Coronary Artery Bypass; Coronary Artery Disease; Disease Progression; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pravastatin

2005
Biomarkers of inflammation and progression of chronic kidney disease.
    Kidney international, 2005, Volume: 68, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Biomarkers; C-Reactive Protein; Disease Progression; Etanercept; Female; Humans; Hyperlipidemias; Immunoglobulin G; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Myocardial Infarction; Pravastatin; Receptors, Tumor Necrosis Factor

2005
Increase in periventricular white matter hyperintensities parallels decline in mental processing speed in a non-demented elderly population.
    Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:2

    Topics: Aged; Aged, 80 and over; Cerebral Infarction; Cerebral Ventricles; Cognition Disorders; Dementia, Vascular; Disease Progression; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Image Processing, Computer-Assisted; Longitudinal Studies; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Pravastatin; Prospective Studies; Reaction Time; Statistics as Topic

2006
Paradoxical increase in lumen size during progression of coronary atherosclerosis: observations from the REVERSAL trial.
    Atherosclerosis, 2006, Volume: 189, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Coronary Angiography; Coronary Artery Disease; Disease Progression; Female; Follow-Up Studies; Heptanoic Acids; Humans; Male; Middle Aged; Pravastatin; Pyrroles; Severity of Illness Index; Treatment Outcome; Ultrasonography, Interventional

2006
Effects of obesity on lipid-lowering, anti-inflammatory, and antiatherosclerotic benefits of atorvastatin or pravastatin in patients with coronary artery disease (from the REVERSAL Study).
    The American journal of cardiology, 2006, Jun-01, Volume: 97, Issue:11

    Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; Body Mass Index; C-Reactive Protein; Coronary Disease; Coronary Vessels; Disease Progression; Endosonography; Female; Heptanoic Acids; Humans; Inflammation; Lipids; Male; Middle Aged; Obesity; Pravastatin; Pyrroles; Risk Factors

2006
Both hepatitis C virus and Chlamydia pneumoniae infection are related to the progression of carotid atherosclerosis in patients undergoing lipid lowering therapy.
    Fukuoka igaku zasshi = Hukuoka acta medica, 2006, Volume: 97, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Carotid Artery Diseases; Chlamydophila Infections; Chlamydophila pneumoniae; Disease Progression; Female; Hepatitis C; Humans; Male; Middle Aged; Pravastatin; Probucol

2006
Association between low plasma vitamin E concentration and progression of early cortical lens opacities.
    American journal of epidemiology, 1996, Sep-01, Volume: 144, Issue:5

    Topics: Adult; Anticholesteremic Agents; Arteriosclerosis; Cataract; Chromatography, High Pressure Liquid; Disease Progression; Finland; Humans; Linear Models; Male; Middle Aged; Pravastatin; Risk Factors; Time Factors; Vitamin E

1996
The Asp9 Asn mutation in the lipoprotein lipase gene is associated with increased progression of coronary atherosclerosis. REGRESS Study Group, Interuniversity Cardiology Institute, Utrecht, The Netherlands. Regression Growth Evaluation Statin Study.
    Circulation, 1996, Oct-15, Volume: 94, Issue:8

    Topics: Amino Acid Sequence; Angioplasty, Balloon, Coronary; Cohort Studies; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Disease Progression; Double-Blind Method; Genes; Heterozygote; Humans; Lipids; Lipoprotein Lipase; Lipoproteins; Middle Aged; Mutation; Pravastatin

1996
Pravastatin reduces carotid intima-media thickness progression in an asymptomatic hypercholesterolemic mediterranean population: the Carotid Atherosclerosis Italian Ultrasound Study.
    The American journal of medicine, 1996, Volume: 101, Issue:6

    Topics: Anticholesteremic Agents; Carotid Stenosis; Disease Progression; Double-Blind Method; Female; Humans; Hypercholesterolemia; Italy; Lipids; Male; Middle Aged; Pravastatin; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography

1996
Simvastatin impairs mitogen-induced proliferation of malignant B-lymphocytes from humans--in vitro and in vivo studies.
    Lipids, 1997, Volume: 32, Issue:3

    Topics: Adult; Aged; B-Lymphocytes; Cell Division; Cholesterol; Chronic Disease; Disease Progression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Leukemia, Lymphoid; Lipids; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Mitogens; Pravastatin; Simvastatin; Thymidine; Tumor Cells, Cultured

1997
Effect of pravastatin (10 mg/day) on progression of coronary atherosclerosis in patients with serum total cholesterol levels from 160 to 220 mg/dl and angiographically documented coronary artery disease. Coronary Artery Regression Study (CARS) Group.
    The American journal of cardiology, 1997, Apr-01, Volume: 79, Issue:7

    Topics: Anticholesteremic Agents; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Coronary Angiography; Coronary Artery Disease; Disease Progression; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pravastatin; Prospective Studies; Time Factors

1997
Intravascular ultrasound analysis of reduction in progression of coronary narrowing by treatment with pravastatin.
    The American journal of cardiology, 1997, Jun-15, Volume: 79, Issue:12

    Topics: Aged; Anticholesteremic Agents; Constriction, Pathologic; Coronary Artery Disease; Disease Progression; Humans; Male; Middle Aged; Pravastatin; Treatment Outcome; Ultrasonography, Interventional

1997
Effect of pravastatin on angiographic restenosis after coronary balloon angioplasty. The PREDICT Trial Investigators. Prevention of Restenosis by Elisor after Transluminal Coronary Angioplasty.
    Journal of the American College of Cardiology, 1997, Volume: 30, Issue:4

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Cholesterol; Combined Modality Therapy; Coronary Angiography; Coronary Disease; Disease Progression; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pravastatin; Prospective Studies; Recurrence; Treatment Outcome

1997
Modulation of lipoprotein(a) atherogenicity by high density lipoprotein cholesterol levels in middle-aged men with symptomatic coronary artery disease and normal to moderately elevated serum cholesterol. Regression Growth Evaluation Statin Study (REGRESS)
    Journal of the American College of Cardiology, 1997, Nov-15, Volume: 30, Issue:6

    Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Coronary Angiography; Coronary Artery Disease; Disease Progression; Double-Blind Method; Humans; Hypercholesterolemia; Lipoprotein(a); Male; Middle Aged; Multivariate Analysis; Pravastatin; Prospective Studies; Reference Values

1997
The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. The Regression Growth Evaluation Statin Study Group.
    The New England journal of medicine, 1998, Jan-08, Volume: 338, Issue:2

    Topics: Anticholesteremic Agents; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Cholesterol, HDL; Coronary Artery Disease; Disease Progression; Dose-Response Relationship, Drug; Glycoproteins; Humans; Hypercholesterolemia; Male; Middle Aged; Polymorphism, Genetic; Pravastatin; Prospective Studies

1998
The inhibitory effects of pravastatin on natural killer cell activity in vivo and on cytotoxic T lymphocyte activity in vitro.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1998, Volume: 17, Issue:4

    Topics: Adjuvants, Immunologic; Anticholesteremic Agents; Cells, Cultured; Cholesterol; Cholesterol, LDL; Coronary Disease; Cyclosporine; Disease Progression; Drug Synergism; Female; Graft Rejection; Graft Survival; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Incidence; Killer Cells, Natural; Male; Middle Aged; Pravastatin; T-Lymphocytes, Cytotoxic; Transplantation, Homologous

1998
Effects of lowering average of below-average cholesterol levels on the progression of carotid atherosclerosis: results of the LIPID Atherosclerosis Substudy. LIPID Trial Research Group.
    Circulation, 1998, May-12, Volume: 97, Issue:18

    Topics: Adult; Aged; Angina, Unstable; Anticholesteremic Agents; Apolipoproteins A; Apolipoproteins B; Arteriosclerosis; Carotid Artery, Common; Carotid Stenosis; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; New Zealand; Pravastatin; Risk Factors; Treatment Outcome; Triglycerides; Ultrasonography

1998
B-mode ultrasound assessment of pravastatin treatment effect on carotid and femoral artery walls and its correlations with coronary arteriographic findings: a report of the Regression Growth Evaluation Statin Study (REGRESS).
    Journal of the American College of Cardiology, 1998, Volume: 31, Issue:7

    Topics: Anticholesteremic Agents; Carotid Arteries; Coronary Angiography; Coronary Artery Disease; Disease Progression; Femoral Artery; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Multicenter Studies as Topic; Pravastatin; Randomized Controlled Trials as Topic; Ultrasonography

1998
Proposed synergistic effect of calcium channel blockers with lipid-lowering therapy in retarding progression of coronary atherosclerosis.
    Cardiovascular drugs and therapy, 1998, Volume: 12 Suppl 1

    Topics: Anticholesteremic Agents; Calcium Channel Blockers; Coronary Artery Disease; Disease Progression; Drug Synergism; Drug Therapy, Combination; Follow-Up Studies; Humans; Pravastatin

1998
Pravastatin prevents clinical events in revascularized patients with average cholesterol concentrations. Cholesterol and Recurrent Events CARE Investigators.
    Journal of the American College of Cardiology, 1999, Volume: 34, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Coronary Artery Bypass; Disease Progression; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Pravastatin; Secondary Prevention; Survival Analysis; Treatment Outcome

1999
Intima-media thickness after pravastatin stabilizes also in patients with moderate to no reduction in LDL-cholesterol levels: the carotid atherosclerosis Italian ultrasound study.
    Atherosclerosis, 2000, Volume: 151, Issue:2

    Topics: Anticholesteremic Agents; Carotid Artery Diseases; Cholesterol, LDL; Disease Progression; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Arteriosclerosis; Lipids; Male; Middle Aged; Pravastatin; Tunica Intima; Tunica Media; Ultrasonography

2000
Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization.
    Circulation, 2001, Feb-20, Volume: 103, Issue:7

    Topics: Aged; Apolipoprotein B-100; Apolipoproteins B; Carotid Arteries; Carotid Artery Diseases; Cell Adhesion Molecules; Cell Death; Cholesterol; Collagen; Disease Progression; Endarterectomy, Carotid; Female; Humans; In Situ Nick-End Labeling; Inflammation; Lipid Metabolism; Lipoproteins; Male; Matrix Metalloproteinase 2; Metalloendopeptidases; Middle Aged; NF-kappa B; Pravastatin; Prospective Studies; Sweden; Tissue Inhibitor of Metalloproteinases; Treatment Outcome

2001
Systolic and pulse blood pressures (but not diastolic blood pressure and serum cholesterol) are associated with alterations in carotid intima-media thickness in the moderately hypercholesterolaemic hypertensive patients of the Plaque Hypertension Lipid Lo
    Journal of hypertension, 2001, Volume: 19, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carotid Arteries; Cholesterol; Disease Progression; Drug Therapy, Combination; Female; Fosinopril; Heart Rate; Humans; Hypercholesterolemia; Hypertension; Italy; Male; Middle Aged; Pravastatin; Systole; Tunica Intima; Ultrasonography

2001
Aggressive versus moderate lipid-lowering therapy in postmenopausal women with hypercholesterolemia: Rationale and design of the Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES) trial.
    American heart journal, 2001, Volume: 141, Issue:5

    Topics: Aged; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Cholesterol, LDL; Coronary Vessels; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Middle Aged; Postmenopause; Pravastatin; Prognosis; Prospective Studies; Pyrroles; Reproducibility of Results; Safety; Tomography, X-Ray Computed

2001
Effect of pravastatin treatment on the evolution of extracoronary atherosclerosis in renal transplant patients.
    Transplantation proceedings, 2002, Volume: 34, Issue:1

    Topics: Arteriosclerosis; Carotid Arteries; Carotid Stenosis; Disease Progression; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Transplantation; Lipids; Male; Postoperative Complications; Pravastatin; Time Factors

2002
Relations of lipoprotein subclass levels and low-density lipoprotein size to progression of coronary artery disease in the Pravastatin Limitation of Atherosclerosis in the Coronary Arteries (PLAC-I) trial.
    The American journal of cardiology, 2002, Jul-15, Volume: 90, Issue:2

    Topics: Anticholesteremic Agents; Cholesterol; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Disease Progression; Female; Humans; Lipoproteins; Lipoproteins, LDL; Male; Middle Aged; Particle Size; Pravastatin; Treatment Outcome

2002

Other Studies

23 other study(ies) available for pravastatin and Disease Exacerbation

ArticleYear
Sustained Focal Vascular Inflammation Accelerates Atherosclerosis in Remote Arteries.
    Arteriosclerosis, thrombosis, and vascular biology, 2020, Volume: 40, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Aortitis; Atherosclerosis; Brachiocephalic Trunk; Collagen; Disease Models, Animal; Disease Progression; Inflammation Mediators; Interleukin-6; Lipid Metabolism; Male; Mice, Knockout, ApoE; Minocycline; Necrosis; Plaque, Atherosclerotic; Pravastatin; Time Factors

2020
Effects of Pravastatin on Type 1 Diabetic Rat Heart with or without Blood Glycemic Control.
    Journal of diabetes research, 2018, Volume: 2018

    Topics: Animals; Blood Glucose; Collagen Type I; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Progression; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Peptidyl-Dipeptidase A; Pravastatin; Rats; Rats, Inbred Lew; Reactive Oxygen Species

2018
Clinical Inquiries. Do statins alter the risk or progression of dementia?
    The Journal of family practice, 2018, Volume: 67, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Cognition; Dementia; Disease Progression; Female; Guidelines as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Simvastatin; United States; United States Food and Drug Administration

2018
Statins for treating stable angina: can statins improve the plaque morphology and angina?
    Future cardiology, 2013, Volume: 9, Issue:2

    Topics: Angina Pectoris; Angina, Stable; Atorvastatin; Disease Progression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Plaque, Atherosclerotic; Pravastatin; Pyrroles; Ultrasonography, Interventional

2013
Impact of HMG-CoA reductase inhibitors on the incidence of polyomavirus-associated nephropathy in renal transplant recipients with human BK polyomavirus viremia.
    Transplant infectious disease : an official journal of the Transplantation Society, 2015, Volume: 17, Issue:4

    Topics: Adult; Aged; BK Virus; Disease Progression; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Polyomavirus Infections; Postoperative Complications; Pravastatin; Treatment Outcome; Tumor Virus Infections; Viremia

2015
Pravastatin has no advantage in small-cell lung cancer.
    The Lancet. Oncology, 2017, Volume: 18, Issue:4

    Topics: Antineoplastic Agents; Clinical Decision-Making; Clinical Trials, Phase III as Topic; Disease Progression; Disease-Free Survival; Humans; Lung Neoplasms; Patient Selection; Pravastatin; Randomized Controlled Trials as Topic; Small Cell Lung Carcinoma; Time Factors; Treatment Outcome

2017
The relation between extent of coronary artery disease measured by quantitative coronary angiography and changes in lipid profile: insights from trials of atherosclerosis regression.
    The Journal of invasive cardiology, 2008, Volume: 20, Issue:6

    Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Coronary Vessels; Disease Progression; Female; Fluorobenzenes; Follow-Up Studies; Heptanoic Acids; Humans; Male; Middle Aged; Pravastatin; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Risk Factors; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome; Ultrasonography, Interventional

2008
Statins for slowing kidney disease progression: an as yet unproven indication.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 52, Issue:3

    Topics: Chronic Disease; Disease Progression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Diseases; Pravastatin; Treatment Outcome

2008
Different effects of commonly prescribed statins on abdominal aortic aneurysm wall biology.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2010, Volume: 39, Issue:5

    Topics: Aged; Aorta; Aortic Aneurysm, Abdominal; Atorvastatin; Biomarkers; Cathepsin A; Cathepsin B; Chi-Square Distribution; Cohort Studies; Disease Progression; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Interleukins; Lymphotoxin-alpha; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Netherlands; Pravastatin; Pyrroles; Risk Assessment; Risk Factors; Simvastatin; Tumor Necrosis Factor-alpha; Vascular Surgical Procedures

2010
Mannose binding lectin 2 haplotypes do not affect the progression of coronary atherosclerosis in men with proven coronary artery disease treated with pravastatin.
    Atherosclerosis, 2011, Volume: 215, Issue:1

    Topics: Coronary Angiography; Coronary Artery Disease; Disease Progression; Genotype; Haplotypes; Humans; Male; Mannose-Binding Lectin; Middle Aged; Polymorphism, Genetic; Pravastatin

2011
HMG-CoA reductase inhibitor (Statin) therapy and coronary atherosclerosis in Japanese subjects: role of high-density lipoprotein cholesterol.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2011, Dec-01, Volume: 11, Issue:6

    Topics: Aged; Area Under Curve; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Disease Progression; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Male; Middle Aged; Plaque, Atherosclerotic; Pravastatin; Prospective Studies; ROC Curve; Sensitivity and Specificity; Treatment Outcome

2011
Low-density lipoprotein lowering and atherosclerosis progression: does more mean less?
    Circulation, 2002, Oct-15, Volume: 106, Issue:16

    Topics: Arteriosclerosis; Atorvastatin; Carotid Arteries; Cholesterol; Cholesterol, LDL; Disease Progression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Pravastatin; Pyrroles; Ultrasonography

2002
Clash of the statins? A trial pitting two popular statins against each other helps answer a far more important question: how low should cholesterol go?
    Harvard heart letter : from Harvard Medical School, 2004, Volume: 14, Issue:6

    Topics: Arteriosclerosis; Atorvastatin; Cholesterol, LDL; Clinical Trials as Topic; Disease Progression; Heptanoic Acids; Humans; Hypolipidemic Agents; Myocardial Infarction; Pravastatin; Pyrroles; Reference Values; Stroke

2004
Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure.
    Cardiovascular research, 2006, Feb-15, Volume: 69, Issue:3

    Topics: Animals; Anticholesteremic Agents; Atrial Natriuretic Factor; Collagen; Disease Progression; Fibronectins; Glutathione; Heart Failure; Hypertrophy, Left Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Models, Animal; Myocardium; Myosin Heavy Chains; NADPH Oxidases; Natriuretic Peptide, Brain; Oxidative Stress; Pravastatin; Rats; Rats, Inbred Dahl; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Chloride, Dietary; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2

2006
The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline-induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS.
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 373, Issue:6

    Topics: Acetylcholine; Animals; Apoptosis; Blood Pressure; Blotting, Western; Body Weight; Caspase 3; Disease Progression; Endothelial Cells; Heart Function Tests; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; In Situ Nick-End Labeling; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Nitroprusside; Poisons; Pravastatin; Pulmonary Artery; Rats; Rats, Wistar; Survival; Vasodilator Agents

2006
Polymorphism of the cholesteryl ester transfer protein gene.
    The New England journal of medicine, 1998, May-28, Volume: 338, Issue:22

    Topics: Carrier Proteins; Cholesterol Ester Transfer Proteins; Coronary Artery Disease; Disease Progression; Glycoproteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Polymorphism, Genetic; Pravastatin

1998
Polymorphism of the cholesteryl ester transfer protein gene.
    The New England journal of medicine, 1998, May-28, Volume: 338, Issue:22

    Topics: Alcohol Drinking; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Diet; Disease Progression; Genotype; Glycoproteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pravastatin

1998
Effects of chronic combined treatment with captopril and pravastatin on the progression of insulin resistance and cardiovascular alterations in an experimental model of obesity in dogs.
    American journal of hypertension, 1998, Volume: 11, Issue:7

    Topics: Animals; Anticholesteremic Agents; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Captopril; Cardiovascular Diseases; Cholesterol; Coronary Vessels; Disease Models, Animal; Disease Progression; Dogs; Drug Therapy, Combination; Heart; Insulin; Insulin Resistance; Linear Models; Male; Multivariate Analysis; Myocardium; Obesity; Pravastatin; Triglycerides

1998
Double filtration plasmapheresis maintains normal adhesion molecule levels.
    Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis, 1998, Volume: 2, Issue:3

    Topics: Anticholesteremic Agents; Arteriosclerosis; Biomarkers; Cell Adhesion Molecules; Cholesterol; Disease Progression; Endothelium, Vascular; Filtration; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Intercellular Adhesion Molecule-1; Myocardial Ischemia; Peripheral Vascular Diseases; Plasmapheresis; Pravastatin; Thrombomodulin; Vascular Cell Adhesion Molecule-1; von Willebrand Factor

1998
Fluvastatin suppresses atherosclerotic progression, mediated through its inhibitory effect on endothelial dysfunction, lipid peroxidation, and macrophage deposition.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:1

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cholesterol, Dietary; Disease Progression; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluvastatin; Hemolytic Plaque Technique; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipid Peroxidation; Lipid Peroxides; Lipids; Macrophages; Male; Muscle, Smooth, Vascular; Pravastatin; Rabbits; Thiobarbituric Acid Reactive Substances

2000
Diabetic retinopathy and serum lipids.
    Singapore medical journal, 2000, Volume: 41, Issue:6

    Topics: Aged; Anticholesteremic Agents; Blood Glucose; Cholesterol; Diabetic Retinopathy; Disease Progression; Exudates and Transudates; Female; Humans; Hyperlipidemias; Laser Coagulation; Lipoproteins, LDL; Pravastatin; Triglycerides

2000
Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis.
    Circulation, 2001, Oct-30, Volume: 104, Issue:18

    Topics: Aged; Aortic Valve Stenosis; Atorvastatin; Calcinosis; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; Echocardiography; Electrocardiography; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Male; Multivariate Analysis; Pravastatin; Pyrroles; Retrospective Studies; Risk Factors; Simvastatin; Treatment Outcome; Triglycerides; Vascular Patency

2001
Cost-effectiveness of intensive glycemic control, intensified hypertension control, and serum cholesterol level reduction for type 2 diabetes.
    JAMA, 2002, May-15, Volume: 287, Issue:19

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Antihypertensive Agents; Cholesterol; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Disease Progression; Humans; Hypoglycemic Agents; Insulin; Markov Chains; Middle Aged; Pravastatin; Quality-Adjusted Life Years; Sulfonylurea Compounds; United States

2002