Page last updated: 2024-08-23

pravastatin and Brain Ischemia

pravastatin has been researched along with Brain Ischemia in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (50.00)29.6817
2010's6 (37.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Dailler, F; Mazard, T; Ritzenthaler, T1
Isaka, Y; Nakamura, T; Nakayama, S; Taguchi, N; Tanaka, M1
Aoki, S; Hosomi, N; Kagimura, T; Kamiyama, K; Kitagawa, K; Koga, M; Maruyama, H; Matsumoto, M; Minematsu, K; Nagai, Y; Nezu, T; Ohtsuki, T; Origasa, H; Suzuki, R; Toyoda, K; Uchiyama, S; Yasaka, M1
Guth, J; Kosteva, A; Levasseur-Franklin, KE; Liotta, E; Lizza, BD; Maas, MB; Naidech, AM; Rosenberg, NF1
Beretta, S; Cai, R; Carone, D; Cattalini, A; Conti, E; Cuccione, E; de Curtis, M; Ferrarese, C; Librizzi, L; Monza, L; Sala, G; Versace, A1
Aoki, S; Fukushima, M; Hosomi, N; Ibayashi, S; Kitagawa, K; Kohriyama, T; Maruyama, H; Matsumoto, M; Minematsu, K; Mori, E; Nagai, Y; Nakamura, M; Nezu, T; Ohtsuki, T; Origasa, H; Shinohara, Y; Sunami, N; Takagi, M; Terayama, Y; Uchiyama, S; Yamaguchi, T; Yokota, C1
Hosomi, N; Kagimura, T; Kitagawa, K; Matsumoto, M; Minematsu, K; Nagai, Y; Nakamura, M; Ohtsuki, T; Origasa, H; Uchiyama, S1
Ay, H; Dalkara, T; Kirazli, S; Kocaefe, C; Moskowitz, MA; Ozcebe, O; Ozgüç, M; Qui, J; Topalkara, K; Yemisci, M1
Abe, A; Katayama, Y; Katsura, K; Nagayama, H; Nishiyama, Y; Otsuka, T; Ueda, M1
Blauw, GJ; Bollen, EL; de Craen, AJ; Ford, I; ten Dam, VH; van Buchem, MA; van den Heuvel, DM; Westendorp, RG1
Carod-Artal, FJ1
Chen, B; Zheng, Z1
Hori, M; Kitagawa, K; Ohyama, N; Sasaki, T; Sugiura, S; Terasaki, Y; Todo, K; Yagita, Y1
Berger, C; Maurer, MH; Schwab, S; Xia, F1
Czosnyka, M; Hutchinson, PJ; Kirkpatrick, PJ; Pickard, JD; Richards, H; Tseng, MY; Turner, CL1
Anderson, NE; Colquhoun, DM; Glasziou, P; Hankey, GJ; Hunt, D; Kirby, AC; MacMahon, S; Simes, RJ; Tonkin, AM; Watson, JD; West, MJ; White, HD1

Reviews

1 review(s) available for pravastatin and Brain Ischemia

ArticleYear
Neuroprotection by pravastatin in acute ischemic stroke in rats.
    Brain research reviews, 2008, Volume: 58, Issue:1

    Topics: Animals; Anticholesteremic Agents; Brain Ischemia; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Pravastatin; Rats; Rats, Wistar; Stroke; Treatment Outcome

2008

Trials

9 trial(s) available for pravastatin and Brain Ischemia

ArticleYear
Long-Term Effect of Pravastatin on Carotid Intima-Media Complex Thickness: The J-STARS Echo Study (Japan Statin Treatment Against Recurrent Stroke).
    Stroke, 2018, Volume: 49, Issue:1

    Topics: Aged; Aged, 80 and over; Asian People; Brain Ischemia; Carotid Intima-Media Thickness; Female; Humans; Japan; Male; Middle Aged; Pravastatin; Stroke; Time Factors

2018
Preadmission statin use does not improve functional outcomes or prevent delayed ischemic events in patients with spontaneous subarachnoid hemorrhage.
    Pharmacotherapy, 2014, Volume: 34, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Cohort Studies; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Intensive Care Units; Logistic Models; Male; Middle Aged; Multivariate Analysis; Pravastatin; Prospective Studies; Subarachnoid Hemorrhage; Time Factors

2014
The Japan Statin Treatment Against Recurrent Stroke (J-STARS): A Multicenter, Randomized, Open-label, Parallel-group Study.
    EBioMedicine, 2015, Volume: 2, Issue:9

    Topics: Aged; Asian People; Brain Ischemia; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Outcome Assessment, Health Care; Pravastatin; Proportional Hazards Models; Recurrence; Stroke

2015
Reduction in High-Sensitivity C-Reactive Protein Levels in Patients with Ischemic Stroke by Statin Treatment: Hs-CRP Sub-Study in J-STARS.
    Journal of atherosclerosis and thrombosis, 2017, Oct-01, Volume: 24, Issue:10

    Topics: Aged; Aged, 80 and over; Brain Ischemia; C-Reactive Protein; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Inflammation; Male; Middle Aged; Pravastatin; Recurrence; Risk; Stroke

2017
Statin potentiates human platelet eNOS activity without enhancing eNOS mRNA and protein levels.
    Cerebrovascular diseases (Basel, Switzerland), 2008, Volume: 26, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Bleeding Time; Blood Platelets; Brain Ischemia; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Ornithine; Platelet Aggregation; Pravastatin; RNA, Messenger; Stroke; Treatment Outcome

2008
Statin treatment decreased serum asymmetric dimethylarginine (ADMA) levels in ischemic stroke patients.
    Journal of atherosclerosis and thrombosis, 2011, Volume: 18, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Atherosclerosis; Atorvastatin; Brain Ischemia; Cholesterol, LDL; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Linear Models; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrroles; Quinolines; Stroke

2011
Effect of pravastatin on cerebral infarcts and white matter lesions.
    Neurology, 2005, May-24, Volume: 64, Issue:10

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Cerebral Infarction; Cholesterol, LDL; Disease Progression; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Arteriosclerosis; Magnetic Resonance Imaging; Male; Nerve Fibers, Myelinated; Pravastatin; Prospective Studies; Telencephalon; Treatment Failure

2005
Biological effects of acute pravastatin treatment in patients after aneurysmal subarachnoid hemorrhage: a double-blind, placebo-controlled trial.
    Journal of neurosurgery, 2007, Volume: 107, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Brain Ischemia; C-Reactive Protein; Cholesterol, LDL; Double-Blind Method; Fibrin Fibrinogen Degradation Products; Fibrinogen; Hematocrit; Hemoglobins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Aneurysm; Leukocyte Count; Lipids; Logistic Models; Middle Aged; Platelet Count; Pravastatin; Risk Factors; Subarachnoid Hemorrhage; Vasospasm, Intracranial

2007
Pravastatin therapy and the risk of stroke.
    The New England journal of medicine, 2000, Aug-03, Volume: 343, Issue:5

    Topics: Adult; Aged; Anticholesteremic Agents; Brain Ischemia; Cerebral Hemorrhage; Coronary Disease; Double-Blind Method; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Pravastatin; Risk Factors; Severity of Illness Index; Stroke

2000

Other Studies

6 other study(ies) available for pravastatin and Brain Ischemia

ArticleYear
Pravastatin may improve neurological outcome following low-grade aneurysmal subarachnoid hemorrhage.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2022, Volume: 98

    Topics: Brain Ischemia; Case-Control Studies; Cerebral Infarction; Humans; Pravastatin; Prognosis; Subarachnoid Hemorrhage; Treatment Outcome

2022
Combined Treatment with Hydrophilic and Lipophilic Statins Improves Neurological Outcomes Following Experimental Cardiac Arrest in Mice.
    Neurocritical care, 2020, Volume: 33, Issue:1

    Topics: Animals; Behavior, Animal; Blood Gas Analysis; Brain Edema; Brain Ischemia; CA1 Region, Hippocampal; Cardiopulmonary Resuscitation; Cytokines; Heart Arrest; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Neuroprotective Agents; Pravastatin; Random Allocation; Simvastatin; Survival Rate

2020
Pravastatin acute neuroprotective effects depend on blood brain barrier integrity in experimental cerebral ischemia.
    Brain research, 2015, Jul-30, Volume: 1615

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Capillary Permeability; Guinea Pigs; Infarction, Middle Cerebral Artery; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 3; Neuroprotective Agents; Pravastatin; Proto-Oncogene Proteins c-akt; Time Factors; Zonula Occludens-1 Protein

2015
Statins and cerebral vasomotor reactivity: implications for a new therapy?
    Stroke, 2006, Volume: 37, Issue:10

    Topics: Adult; Animals; Arginine; Atorvastatin; Brain Ischemia; Cerebrovascular Circulation; Clinical Trials, Phase II as Topic; Endothelium, Vascular; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Intracranial Aneurysm; Mice; Middle Cerebral Artery; Nitric Oxide; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Simvastatin; Stroke; Subarachnoid Hemorrhage; Ultrasonography, Doppler, Transcranial; Vasodilation; Vasomotor System; Vasospasm, Intracranial

2006
Effects of Pravastatin on neuroprotection and neurogenesis after cerebral ischemia in rats.
    Neuroscience bulletin, 2007, Volume: 23, Issue:4

    Topics: Animals; Brain Ischemia; Bromodeoxyuridine; Cell Count; Cell Proliferation; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Male; Microtubule-Associated Proteins; Neurologic Examination; Neurons; Neuropeptides; Neuroprotective Agents; Phosphopyruvate Hydratase; Pravastatin; Rats; Rats, Wistar; Time Factors

2007
Postischemic administration of HMG CoA reductase inhibitor inhibits infarct expansion after transient middle cerebral artery occlusion.
    Brain research, 2007, Nov-21, Volume: 1181

    Topics: Animals; Brain; Brain Ischemia; Disease Models, Animal; Drug Administration Schedule; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Male; Pravastatin; Rats; Rats, Wistar

2007