Page last updated: 2024-08-23

pravastatin and Body Weight

pravastatin has been researched along with Body Weight in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.38)18.7374
1990's7 (21.88)18.2507
2000's9 (28.13)29.6817
2010's12 (37.50)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Grime, K; Paine, SW1
Gari, M; Kumar Mariappan, A; Kumar, A; Kumar, D; Kumar, T; Lingaraju, MC; Parida, S; Rana, A; Sharma, M; Singh, TU1
Favero, BC; García-Arevalo, M; Gomes-Marcondes, MCC; Lorza-Gil, E; Oliveira, HCF1
Beck, B; Donner, D; du Toit, EF; Headrick, JP; Oi, M; Peart, J; Wendt, L1
Marrion, NV; Robertson, JD; Robinson, ES; Stuart, SA1
Costantine, MM; Gamble, P; Hankins, GD; Kechichian, T; Longo, M; McDonnold, M; Saade, GR; Tamayo, E1
Carraway, JW; Gazda, LS; Hall, RD; Laramore, MA; Smith, BH; Vinerean, HV2
Fledderus, JO; Giles, RH; Gremmels, H; Joles, JA; Oosterhuis, NR; Papazova, DA; van Koppen, A; Verhaar, MC1
Araki, K; Kakuma, T; Katsuragi, I; Masaki, T; Yoshimatsu, H1
Ishihara, Y; Kohno, M; Kosaka, H; Mizukawa, M; Noma, T; Obayashi, A; Ohmori, K; Yoshida, J; Yukiiri, K1
Bang, YJ; Byun, HJ; Kim, W; Lee, HS; Lee, SH; Lee, SM; Myung, SJ; Yang, JI; Yoon, JH1
Egawa, T; Hirabara, Y; Ikeda, M; Kataoka, Y; Kusaba, K; Mitsunaga, D; Shuto, H; Takano, Y; Tominaga, K; Yamauchi, A1
Kückelhaus, CS; Kückelhaus, SA; Muniz-Junqueira, MI1
Arai, H; Minami, M; Murayama, T; Tamura, Y; Yokode, M1
Chang, NC; Chou, TF; Lee, TM; Lin, MS; Tsai, CH1
Bouchier-Hayes, D; Casey, RG; Chen, G; Joyce, M; Roche-Nagle, G1
Ichihara, K; Kanda, M; Kasai, T; Keimatsu, N; Satoh, K; Sun, F; Takaguri, A1
Hamano, K; Ito, H; Kobayashi, T; Li, TS; Mikamo, A; Suzuki, R; Takahashi, M1
Bardou, M; Dumas, M; Goirand, F; Guerard, P; Lirussi, F; Rakotoniaina, Z; Rochette, L1
Aizawa, R; Fukaura, Y; Hasebe, M; Ito, M; Morotomi, M; Narisawa, T1
do Nascimento, LO; Maranhão e Pesquisadores, RC; Santos, RD1
Albarrán, OG; García-Robles, R; Rábano, A; Ruilope, LM; Villa, E1
Maranhão, RC; Santos, RD1
Bak, AA; Grobbee, DE; Huizer, J; Leijten, PA; Rila, H1
Asenjo-Barrón, JC; Cárdenas-Vázquez, R; Díaz-Zagoya, JC; Juárez-Oropeza, MA; Martínez, F1
Beinlich, CJ; Ichihara, K; Morgan, HE; Satoh, K; Shirota, F; Tsunajima, T1
Arita, S; Kasraie, A; Mullen, Y; Ohtsuka, S; Smith, CV; Une, S1
Arbeeny, CM; Bergquist, KE1
Manabe, S; Masuda, H; Matsunuma, N; Miyakoshi, N; Sudo, S; Yamashita, K1
Manabe, S; Masuda, H; Matsunuma, N; Miyakoshi, N; Sudo, S; Tanase, H; Yamashita, K1
Masuda, H; Matsunuma, N; Miyakoshi, N; Tarumi, C; Yamashita, K1

Trials

1 trial(s) available for pravastatin and Body Weight

ArticleYear
Diet and pravastatin in moderate hypercholesterolaemia: a randomized trial in 215 middle-aged men free from cardiovascular disease.
    Journal of internal medicine, 1998, Volume: 244, Issue:5

    Topics: Anticholesteremic Agents; Blood Pressure; Body Weight; Combined Modality Therapy; Double-Blind Method; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Patient Compliance; Pravastatin; Treatment Outcome

1998

Other Studies

31 other study(ies) available for pravastatin and Body Weight

ArticleYear
Species differences in biliary clearance and possible relevance of hepatic uptake and efflux transporters involvement.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bile; Body Weight; Dogs; Drug Administration Routes; Humans; Liver; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Organic Anion Transporters; Pharmaceutical Preparations; Protein Binding; Rats; Species Specificity

2013
Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2023, Volume: 98, Issue:8

    Topics: Animals; Body Weight; Collagen; Fibrosis; Isoproterenol; Mice; Pravastatin; Transforming Growth Factor beta

2023
Diabetogenic effect of pravastatin is associated with insulin resistance and myotoxicity in hypercholesterolemic mice.
    Journal of translational medicine, 2019, 08-27, Volume: 17, Issue:1

    Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Cell Line; Diabetes Mellitus, Experimental; Fasting; Female; Glucose Intolerance; Homeostasis; Hypercholesterolemia; Insulin; Insulin Resistance; Insulin Secretion; Mice, Inbred C57BL; Models, Biological; Muscle Fibers, Skeletal; Muscle Proteins; Myotoxicity; Oxidative Stress; Phosphorylation; Pravastatin; Proteolysis; Receptors, LDL; Signal Transduction; Superoxides

2019
Pravastatin improves risk factors but not ischaemic tolerance in obese rats.
    European journal of pharmacology, 2018, May-05, Volume: 826

    Topics: Animals; Blood Glucose; Body Weight; Diet, Carbohydrate Loading; Diet, High-Fat; Disease Models, Animal; Heart; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Insulin Resistance; Lipid Peroxidation; Male; Mitochondria; Mitochondrial Dynamics; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Obesity; Pravastatin; Rats; Rats, Wistar; Risk Factors

2018
Chronic pravastatin but not atorvastatin treatment impairs cognitive function in two rodent models of learning and memory.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Animals; Atorvastatin; Body Weight; Cholesterol; Cognition; Discrimination, Psychological; Heptanoic Acids; Male; Memory; Pravastatin; Pyrroles; Rats; Reversal Learning; Time Factors

2013
The effect of prenatal pravastatin treatment on altered fetal programming of postnatal growth and metabolic function in a preeclampsia-like murine model.
    American journal of obstetrics and gynecology, 2014, Volume: 210, Issue:6

    Topics: Analysis of Variance; Animals; Area Under Curve; Blood Glucose; Body Weight; Cell Cycle Proteins; Disease Models, Animal; Female; Fetal Development; Insulin; Male; Mice; Pravastatin; Pre-Eclampsia; Pregnancy; Receptors, G-Protein-Coupled; Vascular Endothelial Growth Factor Receptor-1

2014
Pravastatin improves glucose regulation and biocompatibility of agarose encapsulated porcine islets following transplantation into pancreatectomized dogs.
    Journal of diabetes research, 2014, Volume: 2014

    Topics: Animals; Anticholesteremic Agents; Area Under Curve; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Experimental; Dogs; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Pancreas; Pravastatin; Sepharose; Swine; Time Factors; Transplantation, Heterologous

2014
No evidence of viral transmission following long-term implantation of agarose encapsulated porcine islets in diabetic dogs.
    Journal of diabetes research, 2014, Volume: 2014

    Topics: Animals; Body Weight; C-Peptide; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dogs; Insulin; Islets of Langerhans; Male; Pravastatin; Sepharose; Swine; Time Factors

2014
Ex vivo exposure of bone marrow from chronic kidney disease donor rats to pravastatin limits renal damage in recipient rats with chronic kidney disease.
    Stem cell research & therapy, 2015, Apr-15, Volume: 6

    Topics: Animals; Apoptosis; Blood Pressure; Body Weight; Bone Marrow Cells; Bone Marrow Transplantation; Cell Movement; Chemokine CXCL5; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glomerular Filtration Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Male; Pravastatin; Rats; Rats, Inbred Lew; Renal Insufficiency, Chronic; Tissue Donors; Transplantation, Homologous

2015
Effects of pravastatin on obesity, diabetes, and adiponectin in diet-induced obese mice.
    Obesity (Silver Spring, Md.), 2008, Volume: 16, Issue:9

    Topics: Adiponectin; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Eating; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Oxygen Consumption; Pravastatin; Random Allocation; Resistin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triglycerides

2008
Effects of combined olmesartan and pravastatin on glucose intolerance and cardiovascular remodeling in a metabolic-syndrome model.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:7

    Topics: Adiponectin; Adipose Tissue, White; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Blood Pressure; Blotting, Western; Body Weight; Cardiovascular System; Drug Therapy, Combination; Eating; Glucose Intolerance; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lipids; Male; Metabolic Syndrome; Nitric Oxide Synthase Type III; Oxidation-Reduction; Pravastatin; Rats; Rats, Inbred OLETF; RNA, Messenger; Superoxides; Tetrahydrofolate Dehydrogenase; Tetrazoles

2009
Synergistic antifibrotic efficacy of statin and protein kinase C inhibitor in hepatic fibrosis.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:1

    Topics: Animals; Apoptosis; Body Weight; Carbon Tetrachloride; Cell Line, Transformed; Disease Models, Animal; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Liver Cirrhosis; Male; Mice; Mice, Inbred BALB C; Mitochondria; Organ Size; Pravastatin; Protein Kinase C; Protein Kinase Inhibitors; Thioacetamide

2010
The statins fluvastatin and pravastatin exert anti-flushing effects by improving vasomotor dysfunction through nitric oxide-mediated mechanisms in ovariectomized animals.
    European journal of pharmacology, 2011, Jan-25, Volume: 651, Issue:1-3

    Topics: Animals; Arteries; Body Weight; Estrogen Replacement Therapy; Fatty Acids, Monounsaturated; Female; Fluvastatin; Hot Flashes; Indoles; Menopause; Mice; Nitric Oxide; Organ Size; Ovariectomy; Physical Conditioning, Animal; Pravastatin; Rats; Skin; Uterus; Vasoconstriction; Vasodilation; Vasomotor System

2011
Influence of long-term treatment with pravastatin on the survival, evolution of cutaneous lesion and weight of animals infected by Leishmania amazonensis.
    Experimental parasitology, 2011, Volume: 127, Issue:3

    Topics: Analysis of Variance; Animals; Antiprotozoal Agents; Body Weight; Cricetinae; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leishmania mexicana; Leishmaniasis, Cutaneous; Male; Mesocricetus; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pravastatin; Statistics, Nonparametric; Survival Rate

2011
Differential effect of statins on diabetic nephropathy in db/db mice.
    International journal of molecular medicine, 2011, Volume: 28, Issue:5

    Topics: Adiposity; Albuminuria; Animals; Blood Pressure; Body Weight; Creatinine; Diabetic Nephropathies; Fluorobenzenes; Insulin Resistance; Male; Mice; Oxidative Stress; Pravastatin; Pyrimidines; Quinolines; Real-Time Polymerase Chain Reaction; Rosuvastatin Calcium; Sulfonamides

2011
Effect of pravastatin on development of left ventricular hypertrophy in spontaneously hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:1

    Topics: Animals; Body Weight; Cardiac Pacing, Artificial; Endothelin-1; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Male; Myocardium; Organ Size; Pravastatin; Rats; Rats, Inbred SHR; RNA, Messenger; Ventricular Function

2005
Pravastatin modulates early diabetic nephropathy in an experimental model of diabetic renal disease.
    The Journal of surgical research, 2005, Volume: 123, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Glomerular Filtration Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pravastatin; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation; Renal Insufficiency; Triglycerides; Urine

2005
HMG-CoA reductase inhibitors do not improve glucose intolerance in spontaneously diabetic Goto-Kakizaki rats.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:11

    Topics: Animals; Atorvastatin; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus; Glucose Intolerance; Glucose Tolerance Test; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Resistance; Male; Pravastatin; Pyrroles; Rats; Rats, Wistar; Simvastatin

2005
Pravastatin improves remodeling and cardiac function after myocardial infarction by an antiinflammatory mechanism rather than by the induction of angiogenesis.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:6

    Topics: Angiogenesis Inducing Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Bone Marrow Cells; Bone Marrow Transplantation; Cell Differentiation; Cells, Cultured; Collagen; Combined Modality Therapy; Drug Evaluation, Preclinical; Endothelium, Vascular; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections; Interleukin-1beta; Male; Myocardial Infarction; Neovascularization, Physiologic; Pravastatin; Random Allocation; Rats; Rats, Zucker; Single-Blind Method; Triglycerides; Ultrasonography; Vascular Endothelial Growth Factor A; Ventricular Remodeling

2006
The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline-induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS.
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 373, Issue:6

    Topics: Acetylcholine; Animals; Apoptosis; Blood Pressure; Blotting, Western; Body Weight; Caspase 3; Disease Progression; Endothelial Cells; Heart Function Tests; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; In Situ Nick-End Labeling; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Nitroprusside; Poisons; Pravastatin; Pulmonary Artery; Rats; Rats, Wistar; Survival; Vasodilator Agents

2006
Chemoprevention by pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, of N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats.
    Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Bile Acids and Salts; Body Weight; Cholesterol; Colonic Neoplasms; Drinking; Eating; Enzyme Inhibitors; Feces; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Methylnitrosourea; Pravastatin; Rats; Rats, Inbred F344; Sterols

1996
[Assessment of short-term effects of awareness programs and pravastatin therapy on subjects from private clinics at high risk for cardiovascular disease].
    Arquivos brasileiros de cardiologia, 1997, Volume: 69, Issue:4

    Topics: Adult; Aged; Blood Pressure; Body Weight; Cardiovascular Diseases; Cholesterol; Evaluation Studies as Topic; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Program Evaluation; Risk Factors

1997
Effects of chronic combined treatment with captopril and pravastatin on the progression of insulin resistance and cardiovascular alterations in an experimental model of obesity in dogs.
    American journal of hypertension, 1998, Volume: 11, Issue:7

    Topics: Animals; Anticholesteremic Agents; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Captopril; Cardiovascular Diseases; Cholesterol; Coronary Vessels; Disease Models, Animal; Disease Progression; Dogs; Drug Therapy, Combination; Heart; Insulin; Insulin Resistance; Linear Models; Male; Multivariate Analysis; Myocardium; Obesity; Pravastatin; Triglycerides

1998
[Comparison of hypercholesterolemic men and women at high risk for atherosclerosis. Study of risk factors and response to pravastatin treatment].
    Arquivos brasileiros de cardiologia, 1998, Volume: 70, Issue:6

    Topics: Adult; Aged; Anticholesteremic Agents; Arteriosclerosis; Blood Pressure; Body Weight; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged; Patient Selection; Pravastatin; Risk Factors; Sex Factors

1998
Comparative toxicity of high doses of vastatins currently used by clinicians, in CD-1 male mice fed with a hypercholesterolemic diet.
    Life sciences, 1999, Volume: 65, Issue:9

    Topics: Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Cholesterol, Dietary; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipids; Liver; Lovastatin; Male; Mice; Mice, Inbred Strains; Organ Size; Pravastatin; Simvastatin; Time Factors; Transaminases; Triglycerides

1999
Limitation of heart growth in neonatal piglets by simvastatin and atorvastatin: comparison with pravastatin.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6

    Topics: Administration, Oral; Animals; Animals, Newborn; Atorvastatin; Blood Pressure; Body Weight; DNA; Heart; Heart Rate; Heart Ventricles; Heptanoic Acids; Mitogen-Activated Protein Kinases; Myocardium; Organ Size; Pravastatin; Proteins; Pyrroles; RNA; Simvastatin; Swine; Water

2001
Prolongation of islet allograft survival in mice by combined treatment with pravastatin and low-dose cyclosporine.
    Cell transplantation, 2001, Volume: 10, Issue:7

    Topics: Animals; Blood Glucose; Body Weight; Cyclosporine; Drug Synergism; Graft Survival; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Immunosuppressive Agents; Islets of Langerhans Transplantation; Kidney; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pravastatin; Transplantation, Homologous

2001
The effect of pravastatin on serum cholesterol levels in hypercholesterolemic diabetic rabbits.
    Biochimica et biophysica acta, 1991, Apr-15, Volume: 1096, Issue:3

    Topics: Animals; Anticholesteremic Agents; Apolipoproteins; Body Weight; Cholesterol; Coconut Oil; Diabetes Complications; Diabetes Mellitus; Diet, Atherogenic; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Male; Naphthalenes; Plant Oils; Pravastatin; Rabbits; Triglycerides

1991
Preliminary dose finding study for subacute toxicological study of pravastatin sodium in monkeys.
    The Journal of toxicological sciences, 1989, Volume: 14 Suppl 1

    Topics: Administration, Oral; Alanine Transaminase; Animals; Anticholesteremic Agents; Aspartate Aminotransferases; Body Temperature; Body Weight; Cholesterol; Diarrhea; Dose-Response Relationship, Drug; Eating; Female; Hematologic Tests; Heptanoic Acids; Macaca fascicularis; Male; Naphthalenes; Organ Size; Pravastatin

1989
Subacute toxicological study in monkeys treated orally with pravastatin sodium for 5 weeks.
    The Journal of toxicological sciences, 1989, Volume: 14 Suppl 1

    Topics: Administration, Oral; Animals; Body Weight; Cholesterol; Diarrhea; Dose-Response Relationship, Drug; Female; Hematologic Tests; Heptanoic Acids; Hypolipidemic Agents; Kidney Function Tests; Liver Function Tests; Macaca fascicularis; Male; Naphthalenes; Organ Size; Pravastatin; Time Factors; Urine

1989
Long term oral administration study of pravastatin sodium to beagles for 104 weeks.
    The Journal of toxicological sciences, 1989, Volume: 14 Suppl 1

    Topics: Animals; Anticholesteremic Agents; Body Weight; Dogs; Electrocardiography; Electroretinography; Estrus; Female; Hematologic Tests; Heptanoic Acids; Kidney Function Tests; Liver Function Tests; Male; Naphthalenes; Occult Blood; Ophthalmoscopy; Organ Size; Pravastatin; Time Factors; Urinalysis

1989