Page last updated: 2024-08-23

pravastatin and Atherogenesis

pravastatin has been researched along with Atherogenesis in 77 studies

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's32 (41.56)29.6817
2010's37 (48.05)24.3611
2020's8 (10.39)2.80

Authors

AuthorsStudies
Nguyen, L; Pham, A; Polic, A; Thompson, JL1
Liu, L; Su, R; Wen, T; Xiao, Z; Xie, Y; Xu, J; Zhang, M; Zhu, L1
Cassola, N; Clezar, CN; Flumignan, CD; Flumignan, RL; Nakano, LC; Trevisani, VF1
Jia, Z; Li, H; Li, M; Li, Q; Liang, X; Su, D; Xuan, W1
Avihingsanon, A; Bautista-Arredondo, S; Bendavid, E; Boettiger, DC; Chaiwarith, R; Chattranukulchai, P; Kahn, JG; Khusuwan, S; Kiertiburanakul, S; Law, MG; Newall, AT; Phillips, A; Ross, J1
Chen, Y; Hu, L; Jia, J; Liu, X; Luo, X; Ou, Y; Shen, W; Shi, H; Sun, S; Zhang, H; Zhou, G1
Andia, ME; Botnar, RM; Lavin Plaza, B; Lorrio, S; Phinikaridou, A; Potter, M; Rashid, I1
Abeydeera, D; Demer, LL; Fong, F; Iriana, S; Lu, M; Patel, NR; Qiao, R; Tintut, Y; Xian, JZ1
Heo, TH; Park, KY2
Chen, X; Li, Y; Lin, L; Wang, S; Zhang, H1
Li, Q; Xiao, S; Zhang, X1
Gao, JH; Lu, JL; Wang, HM1
Liu, G; Liu, M; Wang, M1
Daida, H; Hata, M; Kaku, K; Kawamori, R; Kishimoto, J; Kurabayashi, M; Masuda, I; Nohara, R; Sakuma, I; Yamazaki, T; Yokoi, H; Yoshida, M2
Fukui, K; Hibi, K; Kunishima, T; Michishita, I; Miyake, S; Morino, Y; Muramatsu, T; Nozato, T; Nozue, T; Onishi, Y; Sato, A; Takeyama, Y; Terashima, M; Tohyama, S; Umezawa, S; Yamamoto, S; Yamauchi, T1
Alexopoulos, N; Arepalli, CD; Chen, Z; Hartlage, GR; Kim, S; Melek, BH; Raggi, P; Stillman, AE1
Baumgarten, G; Frede, S; Hilbert, T; Hoeft, A; Klaschik, S; Knuefermann, P; Poth, J1
Daida, H; Kitagawa, Y; Matsushita, Y; Sugihara, M; Teramoto, T1
Ara, N; Iuchi, A; Miyoshi, H; Mizuguchi, Y; Nagase, N; Oishi, Y; Oki, T1
Brazier, J; Brown, WT; Campbell, SE; D'Agostino, RB; Gordon, LB; Kieran, MW; Kleinman, ME; Massaro, J1
Díaz Rodríguez, Á1
Mantilla, T1
Hernández Mijares, A1
González, DF1
Arai, M; Kako, N; Kawasaki, M; Minatoguchi, S; Miwa, H; Nagaya, M; Noda, T; Onishi, N; Ono, K; Saeki, M; Sato, N; Tanaka, R; Watanabe, S; Watanabe, T1
Braamskamp, MJ; Hutten, BA; Wiegman, A1
Ángeles-Garay, U; Carrillo-González, AL; Hernández, C; Jara, L; Medina, G; Olvera-Acevedo, A; Peralta-Amaro, AL; Vera-Lastra, OL1
Liu, J; Lu, P; Pang, X1
Banach, M; Bittner, V; Hovingh, GK; Kastelein, JJ; Lip, GY; Mikhailidis, DP; Ray, K; Rysz, J; Sahebkar, A; Serban, C; Undas, A; Ursoniu, S; Watts, GF1
Calderón-Aranda, E; Cruz-Dominguez, MP; Jara, LJ; Medina, G; Méndez-Flores, S; Vera-Lastra, O1
Heo, TH; Jun, HS; Kwak, MK; Oh, E; Park, KY1
Roever, L1
Baranska, M; Chlopicki, S; Czyzynska-Cichon, I; Drahun, A; Franczyk-Zarow, M; Gasior-Glogowska, M; Jasztal, A; Kostogrys, RB; Kus, E; Manterys, A; Wrobel, TP1
Chae, A; Choi, SH; DeMaria, AN; Messig, M; Miller, E; Nissen, SE; Ntanios, F; Tsimikas, S; Witztum, JL1
del Sol, AI; Nanayakkara, PW1
Avello L, M; Bravo D, M; Calvo M, C; Mennickent C, S1
Gao, PJ; Sun, BG; Zhou, XX1
Fraser, H; Lusis, AJ; Shaposhnik, Z; Trias, J; Wang, X1
Hibi, K; Kunishima, T; Michishita, I; Miyake, S; Morino, Y; Muramatsu, T; Nozue, T; Sato, A; Sozu, T; Takeyama, Y; Tohyama, S; Umezawa, S; Yamamoto, S; Yamauchi, T1
Anantharamaiah, GM; Fogelman, AM; Hama, S; Hough, G; Lehrer, RI; Navab, M; Palgunachari, MN; Ruchala, P; Waring, AJ1
David, S; Fliser, D; Haller, H; Kielstein, JT; Kümpers, P; Lukasz, A1
Koh, KK1
David, S; Fliser, D; Haller, H; Kielstein, JT; Lorenzen, JM; Neunhöffer, H1
Hennekens, C1
Cairns, R; Cannon, CP; Michael Gibson, C; Nazer, B; Ray, KK1
Campos, H; Devlin, JJ; Iakoubova, OA; Kirchgessner, TG; Louie, JZ; Sabatine, MS; Sacks, FM; Shiffman, D1
Arruda, AP; Breder, I; Coope, A; de Oliveira, HC; Dorighello, Gde G; Milanski, M; Razolli, D; Velloso, LA1
Major, A; Mendez-Fernandez, Y1
Abe, A; Katayama, Y; Katsura, K; Nagayama, H; Nishiyama, Y; Otsuka, T; Ueda, M1
Ishibashi, T1
Daida, H; Kitagawa, Y; Teramoto, T1
Dhiman, MK; Petkar, K; Sawant, K; Yedurkar, P1
Huang, C; Huang, Z; Jiang, H; Wu, G; Xie, Q; Xu, L1
Anantharamaiah, GM; Fogelman, AM; Frank, JS; Garber, DW; Hama, S; Handattu, S; Hough, G; Navab, M; Reddy, ST1
Kastelein, JJ; van Leuven, SI1
Frazier, OH; Radovancevic, B; Radovancevic, R; Stojanovic, I; Thomas, CD; Vrtovec, B; Yazdanbakhsh, AP1
Inaba, T; Kato, M; Kitayama, K; Koike, H; Mizuno, M; Sada, T1
Field, KM1
Cannon, CP; Ray, KK1
Kametsu, Y; Kitagawa, Y; Sekiyama, S; Takagi, S1
Fukushima, H; Hirai, T; Honda, O; Horibata, Y; Koga, H; Kugiyama, K; Ogawa, H; Sakamoto, T; Sugiyama, S; Watanabe, K; Yamashita, Y; Yoshimura, M1
de Paula-Coelho, VN; Junqueira, LF; Karnib, SR; Muniz-Junqueira, MI1
Bots, AF; Kastelein, JJ1
Feng, JH; Kang, MF; Li, YQ; Ma, LP; Nie, DN; Wu, YD; Xie, SF; Xu, LZ; Yin, SM1
Hayashi, J; Maeda, S; Ohnishi, H; Okada, K; Sawayama, Y1
Filella, X; Franquesa, J; Marcos, JM; Molina, R; Morales, C; Salinas, R; Trapé, J1
Busser, E; de Kleijn, DP; de Vries, JP; Koekkoek, JA; Moll, FL; Pasterkamp, G; Schoneveld, A; van der Wal, AC; Velema, E; Verheijen, JH; Verhoeven, BA; Virmani, R1
Adams, V; Erbs, S; Goettsch, W; Hambrecht, R; Holtz, J; Krekler, M; Kuss, O; Lenk, K; Mohr, FW; Morawietz, H; Schubert, A; Schuler, G1
Belzunce, M; Orbe, J; Páramo, JA; Rodríguez, JA; Roncal, C1
Dever, G; Kennedy, S; Monopoli, A; Rush, C; Spickett, CM; Tennant, G; Wainwright, CL1
Arakawa, E; Hasegawa, K; Ina, Y; Matsubara, M; Takada, C; Takayama, M; Yao, K1
Angri, V; Calabrò, P; Chiariello, M; Cirillo, P; De Rosa, S; Fiorentino, I; Gargiulo, A; Musto D'Amore, S; Pacileo, M; Petrillo, G; Prevete, N; Sasso, L; Ucci, G1
Averna, MR; Bucciarelli, L; Cefalù, AB; Ciabattoni, G; Davì, G; Davì, V; Ferrante, E; Noto, D; Pettinella, C; Santilli, F1
Havekes, LM; Jukema, JW; Kleemann, R; Kooistra, T; Princen, HM; van der Hoorn, JW1
Benson, R; Dever, GJ; Kennedy, S; Spickett, CM; Wainwright, CL1

Reviews

12 review(s) available for pravastatin and Atherogenesis

ArticleYear
Statins in Pregnancy: Can We Justify Early Treatment of Reproductive Aged Women?
    Current atherosclerosis reports, 2022, Volume: 24, Issue:8

    Topics: Adult; Atherosclerosis; Cardiovascular Diseases; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infant, Newborn; Lactation; Pravastatin; Pregnancy

2022
Pharmacological interventions for asymptomatic carotid stenosis.
    The Cochrane database of systematic reviews, 2023, 08-04, Volume: 8

    Topics: Aspirin; Atherosclerosis; Atorvastatin; Carotid Stenosis; Chlorthalidone; Fluvastatin; Hemorrhage; Humans; Ischemic Stroke; Metoprolol; Pravastatin; Probucol; Rosuvastatin Calcium; Stroke; Warfarin

2023
[Combination of pravastatin and fenofibrate (Pravafenix ®). Safety studies].
    Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis, 2014, Volume: 26 Suppl 1

    Topics: Atherosclerosis; Cardiovascular Diseases; Drug Combinations; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipids; Pravastatin; Risk Factors

2014
Early initiation of statin treatment in children with familial hypercholesterolaemia.
    Current opinion in lipidology, 2015, Volume: 26, Issue:3

    Topics: Atherosclerosis; Child; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Pravastatin; Treatment Outcome

2015
The impact of statin therapy on plasma levels of von Willebrand factor antigen. Systematic review and meta-analysis of randomised placebo-controlled trials.
    Thrombosis and haemostasis, 2016, Volume: 115, Issue:3

    Topics: Adult; Aged; Antigens; Atherosclerosis; Atorvastatin; Cardiovascular Diseases; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Regression Analysis; Risk Assessment; Rosuvastatin Calcium; Simvastatin; Thrombosis; von Willebrand Factor; Young Adult

2016
Pravastatin: an evidence-based statin?
    Expert opinion on drug metabolism & toxicology, 2008, Volume: 4, Issue:6

    Topics: Atherosclerosis; Cardiovascular Diseases; Evidence-Based Medicine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Practice Guidelines as Topic; Pravastatin; Treatment Outcome

2008
[Pleiotropic effects of statins].
    Revista medica de Chile, 2008, Volume: 136, Issue:6

    Topics: Anticholesteremic Agents; Antioxidants; Atherosclerosis; Atorvastatin; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Oxidative Stress; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides

2008
[Pravastatin and acetylsalycilic acid fixed-combination: a strategy to improve cardiovascular outcomes].
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2007, Volume: 7 Spec No 1

    Topics: Aspirin; Atherosclerosis; Coronary Disease; Drug Combinations; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Infarction; Platelet Aggregation Inhibitors; Pravastatin; Randomized Controlled Trials as Topic; Stroke; Treatment Outcome

2007
[Anti-atherosclerotic and anti-inflammatory effects of statin on cardiovascular disease and their mechanisms].
    Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69, Issue:1

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Mevalonic Acid; Monomeric GTP-Binding Proteins; Plaque, Atherosclerotic; Pravastatin; Primary Prevention; Randomized Controlled Trials as Topic; Secondary Prevention

2011
Atorvastatin.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:7

    Topics: Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Cardiovascular Diseases; Carotid Arteries; Cholesterol, LDL; Coronary Artery Disease; Drug Interactions; Endothelium, Vascular; Forecasting; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Leukocytes; Pravastatin; Proportional Hazards Models; Pyrroles; Randomized Controlled Trials as Topic

2005
Effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on high-sensitivity C-reactive protein levels.
    Pharmacotherapy, 2005, Volume: 25, Issue:10

    Topics: Animals; Atherosclerosis; Atorvastatin; C-Reactive Protein; Cardiovascular Diseases; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Metabolic Syndrome; Pravastatin; Pyrroles; Risk Factors; Simvastatin

2005
Optimal goals for statin use in patients with coronary artery disease.
    Current opinion in cardiology, 2005, Volume: 20, Issue:6

    Topics: Atherosclerosis; C-Reactive Protein; Cholesterol, LDL; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Pravastatin; Treatment Outcome

2005

Trials

21 trial(s) available for pravastatin and Atherogenesis

ArticleYear
Effects of Xuezhikang versus Pravastatin on Triglyceride Level in Patients with T2DM and Dyslipidemia: Study Protocol for a Multicenter Randomized Controlled Trial.
    Current vascular pharmacology, 2023, Volume: 21, Issue:3

    Topics: Atherosclerosis; Diabetes Mellitus, Type 2; Dyslipidemias; Humans; Lipids; Multicenter Studies as Topic; Pravastatin; Randomized Controlled Trials as Topic; Triglycerides

2023
Drug effect of atorvastatin on middle cerebral atherosclerotic stenosis and high resolution NMR diagnosis.
    Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:3(Special)

    Topics: Aged; Atherosclerosis; Atorvastatin; Constriction, Pathologic; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Magnetic Resonance Imaging; Male; Middle Aged; Middle Cerebral Artery; Pravastatin; Rosuvastatin Calcium; Simvastatin

2018
Comparison and analysis of the therapeutic effect of different statins in the treatment of atherosclerosis.
    Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:4(Special)

    Topics: Adult; Aged; Atherosclerosis; Atorvastatin; Carotid Arteries; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Plaque, Atherosclerotic; Pravastatin; Simvastatin

2018
Intensive lipid-lowering therapy for slowing progression as well as inducing regression of atherosclerosis in Japanese patients: subanalysis of the JART study.
    International heart journal, 2013, Volume: 54, Issue:1

    Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Carotid Intima-Media Thickness; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; Female; Fluorobenzenes; Humans; Hypercholesterolemia; Japan; Lipid Metabolism; Male; Middle Aged; Outcome Assessment, Health Care; Pharmacovigilance; Pravastatin; Preventive Health Services; Pyrimidines; Risk Assessment; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome

2013
Comparison of effects of serum n-3 to n-6 polyunsaturated fatty acid ratios on coronary atherosclerosis in patients treated with pitavastatin or pravastatin undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2013, Jun-01, Volume: 111, Issue:11

    Topics: Aged; Atherosclerosis; Biomarkers; Coronary Artery Disease; Dose-Response Relationship, Drug; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Percutaneous Coronary Intervention; Pravastatin; Prospective Studies; Quinolines; Severity of Illness Index; Treatment Outcome; Ultrasonography, Interventional

2013
Effect of intensive versus moderate lipid-lowering therapy on epicardial adipose tissue in hyperlipidemic post-menopausal women: a substudy of the BELLES trial (Beyond Endorsed Lipid Lowering with EBT Scanning).
    Journal of the American College of Cardiology, 2013, May-14, Volume: 61, Issue:19

    Topics: Adipose Tissue; Aged; Aged, 80 and over; Atherosclerosis; Atorvastatin; Coronary Artery Disease; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Middle Aged; Postmenopause; Pravastatin; Pyrroles; Vascular Calcification

2013
The relationship between low-density lipoprotein cholesterol levels and the incidence of cardiovascular disease in high-risk patients treated with pravastatin: main results of the APPROACH-J study.
    International heart journal, 2014, Volume: 55, Issue:1

    Topics: Aged; Atherosclerosis; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Japan; Male; Middle Aged; Pravastatin; Prospective Studies

2014
Change in carotid intima-media thickness in a high-risk group of patients by intensive lipid-lowering therapy with rosuvastatin: subanalysis of the JART study.
    International heart journal, 2014, Volume: 55, Issue:2

    Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Carotid Intima-Media Thickness; Cholesterol, LDL; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fluorobenzenes; Follow-Up Studies; Humans; Lipids; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrimidines; Risk Factors; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome

2014
Influence of comorbid cardiovascular risk factors on left atrial-left ventricular interaction in asymptomatic patients: clinical application of two-dimensional speckle-tracking echocardiography.
    International heart journal, 2014, Volume: 55, Issue:2

    Topics: Aged; Atherosclerosis; Atrial Function, Left; Carotid Intima-Media Thickness; Dose-Response Relationship, Drug; Double-Blind Method; Echocardiography; Female; Fluorobenzenes; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrimidines; Risk Factors; Rosuvastatin Calcium; Severity of Illness Index; Sulfonamides; Ventricular Dysfunction, Left; Ventricular Function, Left

2014
Anti-inflammatory and morphologic effects of pitavastatin on carotid arteries and thoracic aorta evaluated by integrated backscatter trans-esophageal ultrasound and PET/CT: a prospective randomized comparative study with pravastatin (EPICENTRE study).
    Cardiovascular ultrasound, 2015, Apr-02, Volume: 13

    Topics: Aged; Anti-Inflammatory Agents; Atherosclerosis; Carotid Arteries; Echocardiography, Transesophageal; Female; Humans; Male; Multimodal Imaging; Positron-Emission Tomography; Pravastatin; Quinolines; Reproducibility of Results; Sensitivity and Specificity; Systems Integration; Thoracic Arteries; Tomography, X-Ray Computed; Treatment Outcome

2015
[Effect of pravastatine plus ezetimibe on carotid intima media thickness in patients with lupus erythematosus].
    Revista medica del Instituto Mexicano del Seguro Social, 2015, Volume: 53 Suppl 1

    Topics: Adult; Anticholesteremic Agents; Atherosclerosis; Carotid Intima-Media Thickness; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Longitudinal Studies; Lupus Erythematosus, Systemic; Middle Aged; Pravastatin; Prospective Studies; Treatment Outcome

2015
Treatment with statin on atheroma regression evaluated by intravascular ultrasound with Virtual Histology (TRUTH Study): rationale and design.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:2

    Topics: Atherosclerosis; Coronary Artery Disease; Coronary Vessels; Endpoint Determination; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Pravastatin; Prospective Studies; Quinolines; Ultrasonography, Interventional; User-Computer Interface

2009
Circulating angiopoietin-2 in essential hypertension: relation to atherosclerosis, vascular inflammation, and treatment with olmesartan/pravastatin.
    Journal of hypertension, 2009, Volume: 27, Issue:8

    Topics: Adult; Aged; Angiopoietin-2; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; C-Reactive Protein; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Imidazoles; Male; Middle Aged; Pravastatin; Prospective Studies; Tetrazoles; Vasculitis

2009
Association between percutaneous coronary intervention and long-term C-reactive protein levels in patients with acute coronary syndromes.
    Journal of thrombosis and thrombolysis, 2010, Volume: 30, Issue:1

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Atherosclerosis; Atorvastatin; C-Reactive Protein; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Observation; Pravastatin; Pyrroles; Treatment Outcome

2010
Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Arg allele from the cholesterol and recurrent events trial.
    The American journal of cardiology, 2010, May-01, Volume: 105, Issue:9

    Topics: Alleles; Atherosclerosis; Cholesterol; DNA; Dose-Response Relationship, Drug; Double-Blind Method; Female; Genetic Predisposition to Disease; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinesins; Male; Middle Aged; Myocardial Infarction; Polymerase Chain Reaction; Polymorphism, Genetic; Pravastatin; Prevalence; Prospective Studies; Risk Factors; Secondary Prevention; Survival Rate; Treatment Outcome; United States

2010
Statin treatment decreased serum asymmetric dimethylarginine (ADMA) levels in ischemic stroke patients.
    Journal of atherosclerosis and thrombosis, 2011, Volume: 18, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Atherosclerosis; Atorvastatin; Brain Ischemia; Cholesterol, LDL; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Linear Models; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrroles; Quinolines; Stroke

2011
Stabilization of carotid atheroma assessed by quantitative ultrasound analysis in nonhypercholesterolemic patients with coronary artery disease.
    Journal of the American College of Cardiology, 2005, Dec-06, Volume: 46, Issue:11

    Topics: Atherosclerosis; C-Reactive Protein; Carotid Artery Diseases; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Imaging; Male; Pravastatin; Prospective Studies; Triglycerides; Ultrasonography, Interventional

2005
Achieving lipid goals in real life: the Dutch DISCOVERY study.
    International journal of clinical practice, 2005, Volume: 59, Issue:12

    Topics: Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Netherlands; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome; Triglycerides

2005
Effect of probucol on elderly hypercholesterolemic patients in the FAST study.
    Fukuoka igaku zasshi = Hukuoka acta medica, 2006, Volume: 97, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Carotid Arteries; Carotid Artery Diseases; Cohort Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Male; Middle Aged; Pravastatin; Probucol; Risk; Treatment Outcome

2006
Endothelial Protection, AT1 blockade and Cholesterol-Dependent Oxidative Stress: the EPAS trial.
    Circulation, 2006, Jul-04, Volume: 114, Issue:1 Suppl

    Topics: Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Biphenyl Compounds; Blood Pressure; Cholesterol; Cholesterol, LDL; Coronary Artery Bypass; Coronary Disease; Drug Therapy, Combination; Elective Surgical Procedures; Gene Expression Regulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Irbesartan; Mammary Arteries; Membrane Glycoproteins; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Natriuretic Peptide, C-Type; Nitric Oxide Synthase Type III; Oxidative Stress; Polymerase Chain Reaction; Pravastatin; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Scavenger Receptors, Class E; Tetrazoles

2006
Decreased plasma soluble RAGE in patients with hypercholesterolemia: effects of statins.
    Free radical biology & medicine, 2007, Nov-01, Volume: 43, Issue:9

    Topics: Anticholesteremic Agents; Arginine; Atherosclerosis; Atorvastatin; Cross-Sectional Studies; Dinoprost; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Pravastatin; Pyrroles; Receptor for Advanced Glycation End Products; Receptors, Immunologic

2007

Other Studies

44 other study(ies) available for pravastatin and Atherogenesis

ArticleYear
HRD1 prevents atherosclerosis-mediated endothelial cell apoptosis by promoting LOX-1 degradation.
    Cell cycle (Georgetown, Tex.), 2020, Volume: 19, Issue:12

    Topics: Apoptosis; Atherosclerosis; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Kruppel-Like Transcription Factors; Lipoproteins, LDL; Pravastatin; Proteolysis; Scavenger Receptors, Class E; Ubiquitin-Protein Ligases; Ubiquitination

2020
Statins for atherosclerotic cardiovascular disease prevention in people living with HIV in Thailand: a cost-effectiveness analysis.
    Journal of the International AIDS Society, 2020, Volume: 23 Suppl 1

    Topics: Adult; Atherosclerosis; Cost-Benefit Analysis; Drug Costs; Female; HIV Infections; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pravastatin; Quality-Adjusted Life Years; Quinolines; Thailand

2020
Pravastatin attenuates atherosclerosis after myocardial infarction by inhibiting inflammatory Ly6C
    The Journal of international medical research, 2020, Volume: 48, Issue:7

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Plaque, Atherosclerotic; Pravastatin

2020
Sustained Focal Vascular Inflammation Accelerates Atherosclerosis in Remote Arteries.
    Arteriosclerosis, thrombosis, and vascular biology, 2020, Volume: 40, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Aortitis; Atherosclerosis; Brachiocephalic Trunk; Collagen; Disease Models, Animal; Disease Progression; Inflammation Mediators; Interleukin-6; Lipid Metabolism; Male; Mice, Knockout, ApoE; Minocycline; Necrosis; Plaque, Atherosclerotic; Pravastatin; Time Factors

2020
Statin Effects on Vascular Calcification: Microarchitectural Changes in Aortic Calcium Deposits in Aged Hyperlipidemic Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2021, Volume: 41, Issue:4

    Topics: Age Factors; Animals; Aorta; Aortic Diseases; Atherosclerosis; Calcium; Disease Models, Animal; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipids; Mice, Inbred C57BL; Mice, Knockout, ApoE; Plaque, Atherosclerotic; Pravastatin; Rupture, Spontaneous; Time Factors; Vascular Calcification

2021
Critical role of TNF inhibition in combination therapy for elderly mice with atherosclerosis.
    Cardiovascular therapeutics, 2017, Volume: 35, Issue:6

    Topics: Aging; Animals; Atherosclerosis; Cholesterol, Dietary; Cytokines; Diet, High-Fat; Drug Therapy, Combination; Etanercept; Fibrinolytic Agents; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; Pravastatin; Receptors, LDL; Succinates; Tumor Necrosis Factor-alpha

2017
Pravastatin polarizes the phenotype of macrophages toward M2 and elevates serum cholesterol levels in apolipoprotein E knockout mice.
    The Journal of international medical research, 2018, Volume: 46, Issue:8

    Topics: Animals; Anticholesteremic Agents; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Cholesterol; Disease Models, Animal; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Plaque, Atherosclerotic; Pravastatin

2018
Pravastatin improves atherosclerosis in mice with hyperlipidemia by inhibiting TREM-1/DAP12.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:15

    Topics: Adaptor Proteins, Signal Transducing; Animals; Anticholesteremic Agents; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Hyperlipidemias; Interleukin-1; Mice; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; Pravastatin; Triggering Receptor Expressed on Myeloid Cells-1; Tumor Necrosis Factor-alpha

2018
Combination therapy with cilostazol and pravastatin improves antiatherogenic effects in low-density lipoprotein receptor knockout mice.
    Cardiovascular therapeutics, 2018, Volume: 36, Issue:6

    Topics: Animals; Aorta; Aortic Diseases; Atherosclerosis; Cell Adhesion Molecules; Cholesterol, Dietary; Cilostazol; Cytokines; Diet, High-Fat; Disease Models, Animal; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lipids; Male; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; Platelet Aggregation Inhibitors; Pravastatin; Receptors, LDL

2018
Anti-atherogenic effects of statins: Impact on angiopoietin-2 release from endothelial cells.
    Biochemical pharmacology, 2013, Nov-15, Volume: 86, Issue:10

    Topics: Acyl Coenzyme A; Angiopoietin-2; Atherosclerosis; Cell Survival; Cells, Cultured; Endothelial Cells; Exocytosis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Nitric Oxide; Nitric Oxide Synthase Type III; Pravastatin; Simvastatin; Weibel-Palade Bodies

2013
Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.
    Circulation, 2014, Jul-01, Volume: 130, Issue:1

    Topics: Adolescent; Adult; Alkyl and Aryl Transferases; Atherosclerosis; Cause of Death; Child; Child, Preschool; Clinical Trials as Topic; Cohort Studies; Dimethylallyltranstransferase; Diphosphonates; Drug Therapy, Combination; Female; Genes, Dominant; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Kaplan-Meier Estimate; Lamin Type A; Male; Multicenter Studies as Topic; Nuclear Proteins; Piperidines; Pravastatin; Progeria; Proportional Hazards Models; Protein Precursors; Protein Prenylation; Pyridines; Treatment Outcome; Young Adult; Zoledronic Acid

2014
[The fixed combination of pravastatin and fenofibrate: what can it provide?].
    Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis, 2014, Volume: 26 Suppl 1

    Topics: Atherosclerosis; Cardiovascular Diseases; Drug Combinations; Dyslipidemias; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type V; Hypolipidemic Agents; Pravastatin; Risk Factors

2014
[Achievement of therapeutic objectives].
    Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis, 2014, Volume: 26 Suppl 1

    Topics: Atherosclerosis; Cardiovascular Diseases; Drug Administration Schedule; Drug Combinations; Dyslipidemias; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Medication Adherence; Pravastatin; Risk Factors

2014
[Treatment of older patients with dyslipidemia].
    Semergen, 2014, Volume: 40 Suppl 1

    Topics: Age Factors; Aged; Atherosclerosis; Dyslipidemias; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Practice Guidelines as Topic; Pravastatin; Quality of Life

2014
Pravastatin inhibits fibrinogen- and FDP-induced inflammatory response via reducing the production of IL-6, TNF-α and iNOS in vascular smooth muscle cells.
    Molecular medicine reports, 2015, Volume: 12, Issue:4

    Topics: Animals; Atherosclerosis; Cell Line; Dose-Response Relationship, Drug; Fibrin Fibrinogen Degradation Products; Fibrinogen; Inflammation; Interleukin-6; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type II; Pravastatin; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2015
Effect of ezetimibe plus pravastatin on endothelial dysfunction in patients with systemic lupus erythematosus.
    Lupus, 2016, Volume: 25, Issue:7

    Topics: Adult; Anticholesteremic Agents; Atherosclerosis; Brachial Artery; C-Reactive Protein; Cholesterol; Drug Therapy, Combination; Endothelium, Vascular; Ezetimibe; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Pravastatin; Ultrasonography; Vasodilation

2016
Pravastatin and Sarpogrelate Synergistically Ameliorate Atherosclerosis in LDLr-Knockout Mice.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Animals; Atherosclerosis; Cell Proliferation; Cytokines; Drug Synergism; Gene Expression Regulation; Gene Knockout Techniques; Hypolipidemic Agents; Intercellular Adhesion Molecule-1; Lipids; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Myocytes, Smooth Muscle; Plaque, Atherosclerotic; Pravastatin; Receptors, LDL; Succinates

2016
Pitavastatin versus Pravastatin in Reduction of Remnant Lipoprotein Cholesterol in Patients with Dyslipidemias.
    Clinical therapeutics, 2016, Volume: 38, Issue:5

    Topics: Atherosclerosis; Cholesterol; Dyslipidemias; Humans; Pravastatin; Triglycerides

2016
Anti-atherosclerotic effects of pravastatin in brachiocephalic artery in comparison with en face aorta and aortic roots in ApoE/LDLR
    Pharmacological reports : PR, 2017, Volume: 69, Issue:1

    Topics: Animals; Anticholesteremic Agents; Aorta; Apolipoproteins E; Atherosclerosis; Brachiocephalic Trunk; Female; Mice; Mice, Knockout; Pravastatin; Receptors, LDL; Treatment Outcome

2017
Relationship between biomarkers of oxidized low-density lipoprotein, statin therapy, quantitative coronary angiography, and atheroma: volume observations from the REVERSAL (Reversal of Atherosclerosis with Aggressive Lipid Lowering) study.
    Journal of the American College of Cardiology, 2008, Jul-01, Volume: 52, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Atherosclerosis; Atorvastatin; Autoantibodies; Biomarkers; Cholesterol, LDL; Coronary Angiography; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin G; Immunoglobulin M; Lipoprotein(a); Male; Malondialdehyde; Middle Aged; Oxidative Stress; Phospholipids; Pravastatin; Prospective Studies; Pyrroles; Research Design

2008
Pravastatin attenuates interferon-gamma action via modulation of STAT1 to prevent aortic atherosclerosis in apolipoprotein E-knockout mice.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:4

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Down-Regulation; Drug Evaluation, Preclinical; Gene Expression Regulation; Hypolipidemic Agents; Interferon Regulatory Factor-1; Interferon-gamma; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pravastatin; STAT1 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins

2009
The synergistic inhibition of atherogenesis in apoE-/- mice between pravastatin and the sPLA2 inhibitor varespladib (A-002).
    Journal of lipid research, 2009, Volume: 50, Issue:4

    Topics: Acetates; Animals; Apolipoproteins E; Aryldialkylphosphatase; Atherosclerosis; Drug Synergism; Enzyme Inhibitors; Indoles; Keto Acids; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phospholipases A2, Secretory; Pravastatin; Prodrugs

2009
A novel method for oral delivery of apolipoprotein mimetic peptides synthesized from all L-amino acids.
    Journal of lipid research, 2009, Volume: 50, Issue:8

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins E; Atherosclerosis; Biological Availability; Female; Humans; Inflammation; Lipoproteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; Niclosamide; Peptides; Pravastatin; Protein Structure, Secondary

2009
Combination treatment to prevent atherosclerosis.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:1

    Topics: Anticholesteremic Agents; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Drug Therapy, Combination; Dyslipidemias; Humans; Hypertension; Pravastatin

2009
Angiotensin II receptor blocker and statins lower elevated levels of osteopontin in essential hypertension--results from the EUTOPIA trial.
    Atherosclerosis, 2010, Volume: 209, Issue:1

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Biomarkers; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Imidazoles; Male; Middle Aged; Osteopontin; Pravastatin; Prospective Studies; Randomized Controlled Trials as Topic; Tetrazoles

2010
Reduction of endoplasmic reticulum stress--a novel mechanism of action of statins in the protection against atherosclerosis.
    Atherosclerosis, 2010, Volume: 212, Issue:1

    Topics: Animals; Antigens, Differentiation; Atherosclerosis; Cell Line; Disease Models, Animal; DNA-Binding Proteins; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Eukaryotic Initiation Factor-2; Fatty Acids; Heat-Shock Proteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Mice; Mice, Knockout; Phosphorylation; Pravastatin; Receptors, LDL; Regulatory Factor X Transcription Factors; Simvastatin; Stress, Physiological; Transcription Factors

2010
Sizing up stability: combination therapy with Apo-AI peptide mimetics and statins in systemic lupus erythematosus-mediated atherosclerosis.
    Arthritis research & therapy, 2010, Volume: 12, Issue:5

    Topics: Animals; Anticholesteremic Agents; Apolipoprotein A-I; Atherosclerosis; Drug Therapy, Combination; Humans; Lupus Erythematosus, Systemic; Mice; Peptides; Plaque, Atherosclerotic; Pravastatin

2010
APPROACH-J study: design, rationale, and baseline data of the affirmation primary prevention with pravastatin in reduction of occlusive atherosclerotic complications in hypercholesterolemia--Japan study.
    Journal of atherosclerosis and thrombosis, 2011, Volume: 18, Issue:12

    Topics: Adult; Atherosclerosis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Japan; Male; Middle Aged; Pravastatin; Primary Prevention

2011
Biopolymeric mucoadhesive bilayer patch of pravastatin sodium for buccal delivery and treatment of patients with atherosclerosis.
    Drug development and industrial pharmacy, 2013, Volume: 39, Issue:5

    Topics: Acrylates; Administration, Buccal; Animals; Area Under Curve; Atherosclerosis; Biological Availability; Drug Delivery Systems; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypromellose Derivatives; Male; Methylcellulose; Mouth Mucosa; Pravastatin; Rabbits; Solubility

2013
Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia.
    Chemical & pharmaceutical bulletin, 2013, Volume: 61, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anticholesteremic Agents; Aorta; Aorta, Abdominal; Atherosclerosis; Cholesterol; Cholesterol, LDL; Diet, High-Fat; Disease Models, Animal; Histamine; Hyperlipidemias; Male; Plaque, Atherosclerotic; Pravastatin; Rabbits; Thrombosis; Thromboxane B2; Triglycerides; Viper Venoms

2013
D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:7

    Topics: Age Factors; Animal Feed; Animals; Anti-Inflammatory Agents; Apolipoprotein A-I; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Chemotaxis, Leukocyte; Cholesterol, HDL; Drug Synergism; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Mucosa; Macaca fascicularis; Male; Mice; Mice, Mutant Strains; Monocytes; Pravastatin

2005
Survival, graft atherosclerosis, and rejection incidence in heart transplant recipients treated with statins: 5-year follow-up.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005, Volume: 24, Issue:9

    Topics: Adolescent; Adult; Aged; Atherosclerosis; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Male; Middle Aged; Pravastatin; Retrospective Studies; Survival Analysis; Treatment Outcome

2005
Effect of combined treatment with an angiotensin II receptor antagonist and an HMG-CoA reductase inhibitor on atherosclerosis in genetically hyperlipidemic rabbits.
    Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atherosclerosis; Blood Pressure; Chemokine CCL2; Cholesterol; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Imidazoles; Immunohistochemistry; Macrophages; Olmesartan Medoxomil; Pravastatin; Rabbits; Tetrazoles; Tunica Intima

2005
Increase in plasma malondialdehyde-modified low-density lipoprotein in patients with atherothrombotic cerebral infarction.
    The Tokai journal of experimental and clinical medicine, 2005, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Atherosclerosis; Carotid Arteries; Cerebral Infarction; Cholesterol, LDL; Female; Humans; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Pravastatin; Statistics as Topic; Ultrasonography, Doppler

2005
Effects of pravastatin on the in vitro phagocytic function and hydrogen peroxide production by monocytes of healthy individuals.
    International immunopharmacology, 2006, Volume: 6, Issue:1

    Topics: Adult; Atherosclerosis; Female; Humans; Hydrogen Peroxide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Middle Aged; Monocytes; Phagocytosis; Pravastatin; Saccharomyces cerevisiae

2006
[The effects of pravastatin on platelet-derived nitric oxide system in rabbits].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2005, Volume: 26, Issue:9

    Topics: Animals; Atherosclerosis; Blood Platelets; Disease Models, Animal; Male; Nitric Oxide; Nitric Oxide Synthase; Pravastatin; Rabbits; RNA, Messenger

2005
Vascular endothelial growth factor serum concentrations in hypercholesterolemic patients.
    Scandinavian journal of clinical and laboratory investigation, 2006, Volume: 66, Issue:3

    Topics: Adult; Aged; Anticholesteremic Agents; Atherosclerosis; C-Reactive Protein; Case-Control Studies; Cholesterol; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Inflammation Mediators; Male; Middle Aged; Neovascularization, Pathologic; Pravastatin; Triglycerides; Vascular Endothelial Growth Factor A

2006
Statin treatment is not associated with consistent alterations in inflammatory status of carotid atherosclerotic plaques: a retrospective study in 378 patients undergoing carotid endarterectomy.
    Stroke, 2006, Volume: 37, Issue:8

    Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Atherosclerosis; Atorvastatin; Carotid Arteries; Carotid Artery Diseases; Cytokines; Dose-Response Relationship, Drug; Endarterectomy, Carotid; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Inflammation; Macrophages; Peptide Hydrolases; Phenotype; Pravastatin; Pyrroles; Retrospective Studies; Simvastatin

2006
The 4G/5G PAI-1 polymorphism influences the endothelial response to IL-1 and the modulatory effect of pravastatin.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:8

    Topics: Analysis of Variance; Atherosclerosis; Cells, Cultured; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Pravastatin; Promoter Regions, Genetic; Umbilical Veins

2006
The nitric oxide-donating pravastatin derivative, NCX 6550 [(1S-[1alpha(betaS*, deltaS*), 2alpha, 6alpha, 8beta-(R*), 8a alpha]]-1,2,6,7,8,8a-Hexahydro-beta, delta, 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic acid 4-(nitrooxy)but
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Cell Adhesion; Chemokine CCL2; Cholesterol; Endothelium, Vascular; Female; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Nitrates; Nitric Oxide Donors; Pravastatin; Reactive Oxygen Species; Spleen; Thrombin

2007
Comparison of the antiatherosclerotic effects of dihydropyridine calcium channel blocker and HMG-CoA reductase inhibitor on hypercholesterolemic rabbits.
    Vascular pharmacology, 2007, Volume: 46, Issue:4

    Topics: Animals; Aorta, Thoracic; Atherosclerosis; Calcium Channel Blockers; Cholesterol; Dihydropyridines; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperplasia; Male; Pravastatin; Rabbits; RNA, Messenger; Scavenger Receptors, Class E; Time Factors; Tunica Intima; Up-Regulation; Vascular Cell Adhesion Molecule-1; Vasodilation

2007
HMG-CoA reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells.
    Journal of vascular research, 2007, Volume: 44, Issue:6

    Topics: Atherosclerosis; Cell Adhesion; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Intercellular Adhesion Molecule-1; Leukocytes; Lovastatin; NF-kappa B; Nicotine; Nicotinic Agonists; Pravastatin; Protein Kinase C; Reactive Oxygen Species; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Simvastatin; Smoking; Superoxide Dismutase; Time Factors; Vascular Cell Adhesion Molecule-1

2007
Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice.
    Journal of hypertension, 2007, Volume: 25, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoprotein E3; Atherosclerosis; Blood Pressure; Collagen; Diet, Atherogenic; Drug Synergism; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Inflammation; Lipids; Macrophages; Mice; Mice, Transgenic; Monocytes; Muscle, Smooth, Vascular; Pravastatin; Recombinant Proteins; Serum Amyloid A Protein; T-Lymphocytes; Tetrazoles

2007
Phospholipid chlorohydrin induces leukocyte adhesion to ApoE-/- mouse arteries via upregulation of P-selectin.
    Free radical biology & medicine, 2008, Feb-01, Volume: 44, Issue:3

    Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Arteries; Atherosclerosis; Cell Adhesion; Chlorohydrins; Hypochlorous Acid; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Lipoproteins, LDL; Mice; Mice, Knockout; Nitrates; P-Selectin; Phosphatidylcholines; Phospholipids; Pravastatin; Reactive Oxygen Species; Up-Regulation

2008