pravastatin has been researched along with Alloxan Diabetes in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.57) | 18.7374 |
| 1990's | 5 (17.86) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 13 (46.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Favero, BC; García-Arevalo, M; Gomes-Marcondes, MCC; Lorza-Gil, E; Oliveira, HCF | 1 |
| Jeon, Y; Kim, S; Lee, JH; Min, JJ; Ryu, DK; Shin, BS; Shin, YH | 1 |
| Casiano, H; Crespo, MJ; Cruz, N; Hernandez, C; Quidgley, J; Rivera, K; Torres, H | 1 |
| Hori, E; Itoh, T; Kajikuri, J; Kikuchi, C; Kimura, K; Matsunaga, T; Nagami, C | 1 |
| Hu, MY; Jia, LL; Li, F; Liu, C; Liu, L; Liu, XD; Xu, D; Yang, Y; Zhang, M; Zhong, ZY | 1 |
| Carraway, JW; Gazda, LS; Hall, RD; Laramore, MA; Smith, BH; Vinerean, HV | 2 |
| Gad, HI | 2 |
| Li, F; Ling, Z; Liu, C; Liu, L; Liu, X; Shu, N; Xu, D; Zhang, M; Zhong, Z | 1 |
| Li, F; Ling, ZL; Liu, C; Liu, L; Liu, XD; Shu, N; Wang, ZJ; Zhang, M; Zhong, ZY | 1 |
| Bouchier-Hayes, D; Chan, F; Hanson, R; Laing, T | 1 |
| Fukushima, S; Hasegawa, Y; Inotsume, N; Kishimoto, S; Shibatani, N; Takeuchi, Y | 1 |
| Aoki, T; Imaeda, A; Kaneko, T; Kondo, Y; Nagase, H; Nakamura, N; Yoshikawa, T | 1 |
| Ichihara, K; Kanda, M; Satoh, K | 1 |
| Bouchier-Hayes, D; Casey, RG; Chen, G; Joyce, M; Roche-Nagle, G | 1 |
| Campesi, I; Emanueli, C; Gadau, S; Kraenkel, N; Madeddu, P; Meloni, M; Monopoli, A; Ongini, E | 1 |
| Huang, Z; Jansson, L; Sjöholm, A | 1 |
| Agardh, CD; Agardh, E; Gustavsson, C; Hagert, P | 1 |
| Fujii, T; Kuwano, H; Onimaru, M; Sueishi, K; Yonemitsu, Y | 1 |
| Arita, S; Atiya, A; Joh, S; Kasraie, A; Mullen, Y; Ohtsuka, S; Saul, J; Une, S | 1 |
| Kamata, K; Kasuya, Y; Suenaga, H; Sugiura, M | 1 |
| Arita, S; Atiya, A; Kasraie, A; Mullen, Y; Ohtsuka, S; Shevlin, L; Une, S | 2 |
| Hayashi, A; Hidaka, H; Hiramatsu, M; Kanno, T; Ueshima, H | 1 |
| Arita, S; Maruyama, M; Mullen, Y; Nagai, T; Sakamoto, Y; Smith, CV | 1 |
| Dumont, AS; Dumont, RJ; Fedak, PM; Hyndman, ME; Kassell, NF; Sutherland, GR; Verma, S | 1 |
| Ebisuno, S; Isohashi, F; Nakanishi, Y; Sakamoto, Y | 1 |
28 other study(ies) available for pravastatin and Alloxan Diabetes
| Article | Year |
|---|---|
Diabetogenic effect of pravastatin is associated with insulin resistance and myotoxicity in hypercholesterolemic mice.
Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Cell Line; Diabetes Mellitus, Experimental; Fasting; Female; Glucose Intolerance; Homeostasis; Hypercholesterolemia; Insulin; Insulin Resistance; Insulin Secretion; Mice, Inbred C57BL; Models, Biological; Muscle Fibers, Skeletal; Muscle Proteins; Myotoxicity; Oxidative Stress; Phosphorylation; Pravastatin; Proteolysis; Receptors, LDL; Signal Transduction; Superoxides | 2019 |
Effects of Pravastatin on Type 1 Diabetic Rat Heart with or without Blood Glycemic Control.
Topics: Animals; Blood Glucose; Collagen Type I; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Progression; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Peptidyl-Dipeptidase A; Pravastatin; Rats; Rats, Inbred Lew; Reactive Oxygen Species | 2018 |
Daily administration of atorvastatin and simvastatin for one week improves cardiac function in type 1 diabetic rats.
Topics: Animals; Atorvastatin; Blood Glucose; Cardiac Output; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Administration Schedule; Heart; Heart Rate; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pravastatin; Pyrroles; Rats; Rats, Sprague-Dawley; Simvastatin; Ventricular Function, Left | 2014 |
Aortic superoxide production at the early hyperglycemic stage in a rat type 2 diabetes model and the effects of pravastatin.
Topics: Animals; Aorta; Blood Glucose; Catalase; Coronary Disease; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nitric Oxide Synthase Type III; Pravastatin; Protein Kinase C; Rats, Long-Evans; Superoxides | 2014 |
Co-administration of paroxetine and pravastatin causes deregulation of glucose homeostasis in diabetic rats via enhanced paroxetine exposure.
Topics: Animals; Anticholesteremic Agents; Antidepressive Agents, Second-Generation; Blood Glucose; Cell Line; Depression; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Drug Interactions; Hypercholesterolemia; Insulin; Male; Paroxetine; Pravastatin; Rats; Rats, Sprague-Dawley; Serotonin | 2014 |
Pravastatin improves glucose regulation and biocompatibility of agarose encapsulated porcine islets following transplantation into pancreatectomized dogs.
Topics: Animals; Anticholesteremic Agents; Area Under Curve; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Experimental; Dogs; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Pancreas; Pravastatin; Sepharose; Swine; Time Factors; Transplantation, Heterologous | 2014 |
No evidence of viral transmission following long-term implantation of agarose encapsulated porcine islets in diabetic dogs.
Topics: Animals; Body Weight; C-Peptide; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dogs; Insulin; Islets of Langerhans; Male; Pravastatin; Sepharose; Swine; Time Factors | 2014 |
Does combined peroxisome proliferator-activated receptors-agonist and pravastatin therapy attenuate the onset of diabetes-induced experimental nephropathy?
Topics: Animals; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycated Hemoglobin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Kidney; Lipid Peroxides; Peroxisome Proliferator-Activated Receptors; Pravastatin; Rats; Rosiglitazone; Thiazolidinediones; Transferrin; Tumor Necrosis Factor-alpha | 2014 |
Co-administration of paroxetine increased the systemic exposure of pravastatin in diabetic rats due to the decrease in liver distribution.
Topics: Administration, Intravenous; Administration, Oral; Animals; Body Fluids; Carbamates; Cell Separation; Diabetes Mellitus, Experimental; Diet, High-Fat; Disease Models, Animal; Feces; Hepatocytes; Intestinal Absorption; Liver; Male; Paroxetine; Piperidines; Pravastatin; Rats, Sprague-Dawley; Tissue Distribution | 2015 |
Differential effects of pravastatin on the pharmacokinetics of paroxetine in normal and diabetic rats.
Topics: Animals; Anticholesteremic Agents; Biological Transport; Diabetes Mellitus, Experimental; Hepatocytes; Liver; Paroxetine; Pravastatin; Rats; Selective Serotonin Reuptake Inhibitors | 2017 |
Effect of pravastatin on experimental diabetic wound healing.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Pravastatin; Rats; Rats, Sprague-Dawley; Skin; Wound Healing; Wounds and Injuries | 2010 |
The disposition of pravastatin in a rat model of streptozotocin-induced diabetes and organic anion transporting polypeptide 2 and multidrug resistance-associated protein 2 expression in the liver.
Topics: Animals; Area Under Curve; Bile; Biological Transport; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Gene Expression; Liver; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Pravastatin; Rats; Rats, Inbred Strains; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Effects of pravastatin or 12/15 lipoxygenase pathway inhibitors on indices of diabetic nephropathy in an experimental model of diabetic renal disease.
Topics: Albuminuria; Animals; Anticholesteremic Agents; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Insulin; Kidney; Male; Oxidative Stress; Pravastatin; Rats; Rats, Wistar; Signal Transduction; Treatment Outcome | 2012 |
Antioxidative effects of fluvastatin and its metabolites against DNA damage in streptozotocin-treated mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Creatinine; Deoxyguanosine; Diabetes Mellitus, Experimental; DNA; DNA Damage; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Kidney; Liver; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Pravastatin; Simvastatin; Weight Gain | 2002 |
Effects of atorvastatin and pravastatin on glucose tolerance in diabetic rats mildly induced by streptozotocin.
Topics: Administration, Oral; Animals; Atorvastatin; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Glucose; Glucose Tolerance Test; Heptanoic Acids; Injections, Intravenous; Insulin; Insulin Secretion; Male; Pravastatin; Pyrroles; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors | 2003 |
Pravastatin modulates early diabetic nephropathy in an experimental model of diabetic renal disease.
Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Glomerular Filtration Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pravastatin; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation; Renal Insufficiency; Triglycerides; Urine | 2005 |
Nitropravastatin stimulates reparative neovascularisation and improves recovery from limb Ischaemia in type-1 diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Pravastatin | 2007 |
Gender-specific regulation of pancreatic islet blood flow, insulin levels and glycaemia in spontaneously diabetic Goto-Kakizaki rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Irbesartan; Islets of Langerhans; Male; Pravastatin; Rats; Rats, Mutant Strains; Regional Blood Flow; Sex Factors; Tetrazoles | 2008 |
Inflammatory markers in nondiabetic and diabetic rat retinas exposed to ischemia followed by reperfusion.
Topics: Animals; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Docosahexaenoic Acids; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Pravastatin; Rats; Rats, Wistar; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Statins restore ischemic limb blood flow in diabetic microangiopathy via eNOS/NO upregulation but not via PDGF-BB expression.
Topics: Animals; Becaplermin; Blood Glucose; Cells, Cultured; Cholesterol, LDL; Combined Modality Therapy; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Foot; Enzyme Inhibitors; Genetic Therapy; Glycation End Products, Advanced; Hindlimb; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet-Derived Growth Factor; Pravastatin; Proto-Oncogene Proteins c-sis; Quinolines; Regional Blood Flow; Signal Transduction; Time Factors; Up-Regulation | 2008 |
Islet protective effect of pravastatin from nonspecific inflammation in mouse pancreatic islet isografts.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Inflammation; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Niacinamide; Pravastatin; Transplantation, Isogeneic | 1996 |
[Effect of cholestyramine on angiopathies in cholesterol-fed mice and diabetic mice].
Topics: Animals; Anticholesteremic Agents; Cholesterol, Dietary; Cholestyramine Resin; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Hypercholesterolemia; Male; Mice; Mice, Inbred ICR; Pravastatin; Vascular Diseases; Vasodilation | 1995 |
Pravastatin and low-dose cyclosporine treatment prevent islet allograft rejection in mice.
Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pravastatin; Transplantation, Homologous | 1998 |
Prevention of primary islet isograft nonfunction in mice with pravastatin.
Topics: Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glycosuria; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Islets of Langerhans Transplantation; Male; Mice; Mice, Inbred BALB C; Pravastatin; Transplantation, Isogeneic | 1998 |
Enzyme immunoassay of urinary mevalonic acid and its clinical application.
Topics: Adult; Animals; Antibodies, Monoclonal; Cross Reactions; Diabetes Mellitus, Experimental; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoenzyme Techniques; Male; Mevalonic Acid; Middle Aged; Pravastatin; Rats; Rats, Sprague-Dawley; Reference Values | 1998 |
Islet graft primary nonfunction and its prevention.
Topics: Animals; Animals, Newborn; Antioxidants; Blood Glucose; Chromans; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Graft Survival; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pravastatin; Subrenal Capsule Assay; Transplantation, Homologous; Transplantation, Isogeneic | 2000 |
Improvement of endothelial function in insulin-resistant carotid arteries treated with pravastatin.
Topics: Animals; Carotid Stenosis; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelium, Vascular; Hypertension; Insulin Resistance; Male; Nitric Oxide; Pravastatin; Rats; Rats, Sprague-Dawley; Risk Factors; Stroke; Vascular Resistance | 2001 |
Acetyl-CoA hydrolase: relation between activity and cholesterol metabolism in rat.
Topics: Acetyl-CoA Hydrolase; Animals; Anticholesteremic Agents; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Clofibric Acid; Cytosol; Diabetes Mellitus, Experimental; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Naphthalenes; Pravastatin; Rats; Thiolester Hydrolases | 1988 |