pravastatin has been researched along with Aging in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Cabral, WA; Collins, FS; Cubria, MB; DuBose, A; Erdos, MR; Kamalapathy, P; Karim, L; Masoudi, A; Nazarian, A; Oftadeh, R; Snyder, BD; Suarez, S | 1 |
| Heo, TH; Park, KY | 1 |
| Gao, M; Johnston, RK; Matthews, AB; Skolnick, J; Snell, TW; Zhou, H | 1 |
| Jiang, K | 1 |
| Celik-Ozenci, C; Dalaklioglu, S; Sahin, P; Tasatargil, A | 1 |
| Blauw, GJ; Bollen, EL; Buckley, BM; de Craen, AJ; Ford, I; Jolles, J; Jukema, JW; Macfarlane, PW; Murphy, MB; Packard, CJ; Sattar, N; Shepherd, J; Stott, DJ; Trompet, S; van Vliet, P; Westendorp, RG | 1 |
| Abouelnaga, ZA; Alhaj, MA; Awad, MM; Citro, LA; El-Sayed, O; Elnakish, MT; Hassanain, HH; Hassona, MD; Khan, M; Kulkarni, A; Kuppusamy, P; Moldovan, L; Sayyid, M | 1 |
| de Craen, AJ; Ford, I; Jukema, JW; McInnes, IB; Murray, HM; Packard, CJ; Sattar, N; Stott, DJ; Trompet, S; Welsh, P; Westendorp, RG | 1 |
| Ishida, K; Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K | 1 |
| Kim, J; Lim, SW; Piao, SG; Song, JH; Yang, CW; Yoon, HE | 1 |
| Stefanec, T | 1 |
| Brown, EA; Gaw, A; Murray, HM | 1 |
| Blauw, GJ; Bollen, EL; Box, FM; de Craen, AJ; Murray, HM; ten Dam, VH; van Buchem, MA; van den Heuvel, DM; Westendorp, RG | 1 |
| Brouilette, SW; Ford, I; McMahon, AD; Moore, JS; Packard, CJ; Samani, NJ; Shepherd, J; Thompson, JR | 1 |
| Blauw, GJ; Box, FM; de Craen, AJ; Jukema, JW; Palm-Meinders, IH; Reiber, JH; van Buchem, MA; van der Geest, RJ; van der Grond, J | 1 |
| Bär, PR; Bredman, JJ; Cohen, LH; De Vries, AC; Vermeer, MA | 1 |
| Sugiyama, S | 1 |
| Hatanaka, T | 1 |
| Gaw, A | 1 |
2 review(s) available for pravastatin and Aging
| Article | Year |
|---|---|
Clinical pharmacokinetics of pravastatin: mechanisms of pharmacokinetic events.
Topics: Adult; Aged; Aging; Area Under Curve; Biotransformation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Absorption; Male; Pravastatin; Sex Characteristics; Tissue Distribution | 2000 |
Healthy ageing: addressing acute coronary syndrome?
Topics: Acute Disease; Adult; Age Factors; Aged; Aging; Australia; Coronary Disease; Endothelium, Vascular; Evidence-Based Medicine; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Middle Aged; New Zealand; Pravastatin; Risk Factors; Sex Factors; Simvastatin; Syndrome; United States | 2001 |
4 trial(s) available for pravastatin and Aging
| Article | Year |
|---|---|
Pravastatin and cognitive function in the elderly. Results of the PROSPER study.
Topics: Aged; Aging; Anticholesteremic Agents; Cognition; Cognition Disorders; Female; Follow-Up Studies; Humans; Male; Neuropsychological Tests; Nootropic Agents; Pravastatin; Prospective Studies; Time Factors; Treatment Outcome | 2010 |
Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-10; Logistic Models; Male; Odds Ratio; Pravastatin; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Time Factors | 2011 |
Lack of effect of pravastatin on cerebral blood flow or parenchymal volume loss in elderly at risk for vascular disease.
Topics: Aged; Aged, 80 and over; Aging; Blood Circulation Time; Blood Flow Velocity; Blood Pressure; Brain; Carotid Arteries; Cerebrovascular Circulation; Cholesterol; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Imaging; Male; Pravastatin; Prospective Studies; Software; Time Factors | 2005 |
Pravastatin decreases wall shear stress and blood velocity in the internal carotid artery without affecting flow volume: results from the PROSPER MRI study.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Anticholesteremic Agents; Blood Flow Velocity; Blood Viscosity; Blood Volume; Carotid Artery Diseases; Carotid Artery, Internal; Carotid Stenosis; Cerebrovascular Circulation; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Placebos; Pravastatin; Prospective Studies; Stress, Mechanical; Time Factors | 2007 |
13 other study(ies) available for pravastatin and Aging
| Article | Year |
|---|---|
Evaluation of musculoskeletal phenotype of the G608G progeria mouse model with lonafarnib, pravastatin, and zoledronic acid as treatment groups.
Topics: Aging; Animals; Bone and Bones; Bone Density Conservation Agents; Cartilage; Disease Models, Animal; Femur; Glycosaminoglycans; Joints; Lamin Type A; Mice; Mice, Transgenic; Mutation; Osteoarthritis; Phenotype; Piperidines; Pravastatin; Progeria; Protein Processing, Post-Translational; Pyridines; X-Ray Microtomography; Zoledronic Acid | 2020 |
Critical role of TNF inhibition in combination therapy for elderly mice with atherosclerosis.
Topics: Aging; Animals; Atherosclerosis; Cholesterol, Dietary; Cytokines; Diet, High-Fat; Drug Therapy, Combination; Etanercept; Fibrinolytic Agents; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; Pravastatin; Receptors, LDL; Succinates; Tumor Necrosis Factor-alpha | 2017 |
Repurposed FDA-approved drugs targeting genes influencing aging can extend lifespan and healthspan in rotifers.
Topics: Aging; Animals; Capecitabine; Databases, Pharmaceutical; Drug Evaluation, Preclinical; Drug Repositioning; Erythromycin; Female; Genes, Helminth; Glutamates; Healthy Aging; Longevity; Male; Models, Animal; Pravastatin; Reproduction; Rotifera; United States; United States Food and Drug Administration; User-Computer Interface | 2018 |
Drug development for progeria yields insights into normal aging.
Topics: Aging; Child; Clinical Trials as Topic; Diphosphonates; Drug Discovery; Humans; Imidazoles; Lamin Type A; Mutation; Piperidines; Pravastatin; Progeria; Pyridines; Time Factors; Zoledronic Acid | 2013 |
Pravastatin improves the impaired nitric oxide-mediated neurogenic and endothelium-dependent relaxation of corpus cavernosum in aged rats.
Topics: Aging; Animals; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Penis; Pravastatin; Rats, Wistar | 2014 |
Cardiac remodeling caused by transgenic overexpression of a corn Rac gene.
Topics: Aging; Amino Acid Sequence; Analysis of Variance; Animals; Echocardiography; Genotype; Hypertrophy, Left Ventricular; Integrin alpha1; Integrin beta1; Magnetic Resonance Imaging; Male; MAP Kinase Signaling System; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Myocardium; Myosin Heavy Chains; Phenotype; Plant Proteins; Pravastatin; Promoter Regions, Genetic; rac1 GTP-Binding Protein; Superoxides; Thyroxine; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2011 |
Pravastatin normalizes endothelium-derived contracting factor-mediated response via suppression of Rho-kinase signalling in mesenteric artery from aged type 2 diabetic rat.
Topics: Aging; Animals; Diabetes Mellitus, Type 2; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mesenteric Arteries; Pravastatin; Rats; Rats, Inbred OLETF; rho-Associated Kinases; Signal Transduction | 2012 |
Statin upregulates the expression of klotho, an anti-aging gene, in experimental cyclosporine nephropathy.
Topics: Aging; Animals; Cyclosporine; Glucuronidase; Immunosuppressive Agents; Kidney; Kidney Diseases; Klotho Proteins; Male; Mice; Pravastatin; Up-Regulation | 2012 |
The PROSPER trial.
Topics: Age Factors; Aged; Aging; Anticholesteremic Agents; Endothelial Growth Factors; Humans; Intercellular Signaling Peptides and Proteins; Lymphokines; Neoplasms; Neovascularization, Pathologic; Pravastatin; Predictive Value of Tests; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Plasma lipoprotein(a) [Lp(a)] concentrations and cardiovascular events in the elderly: evidence from the prospective study of pravastatin in the elderly at risk (PROSPER).
Topics: Aged; Aged, 80 and over; Aging; Anticholesteremic Agents; Cardiovascular Diseases; Cognition Disorders; Cohort Studies; Disabled Persons; Female; Humans; Lipoprotein(a); Male; Pravastatin; Predictive Value of Tests; Risk Factors | 2005 |
Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study.
Topics: Aging; Blood Pressure; Case-Control Studies; Cholesterol; Coronary Disease; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Polymerase Chain Reaction; Pravastatin; Risk Factors; Scotland; Telomere | 2007 |
Cholesterol content of the rat lens is lowered by administration of simvastatin, but not by pravastatin.
Topics: Aging; Animals; Anticholesteremic Agents; Cholesterol; Dose-Response Relationship, Drug; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lens, Crystalline; Lovastatin; Microsomes, Liver; Organ Culture Techniques; Pravastatin; Rats; Rats, Wistar; Simvastatin; Time Factors | 1993 |
HMG CoA reductase inhibitor accelerates aging effect on diaphragm mitochondrial respiratory function in rats.
Topics: Aging; Animals; Cell Respiration; Diaphragm; Electron Transport; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mitochondria, Heart; Mitochondria, Liver; Mitochondria, Muscle; Multienzyme Complexes; NAD(P)H Dehydrogenase (Quinone); Oxidoreductases; Pravastatin; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Ubiquinone | 1998 |