practolol has been researched along with Muscle Contraction in 35 studies
Practolol: A beta-1 adrenergic antagonist that has been used in the emergency treatment of CARDIAC ARRYTHMIAS.
practolol : N-(4-Hydroxyphenyl)acetamide in which the hydrogen of the phenolic hydroxy group is substituted by a 3-(isopropylaminoamino)-2-hydroxypropyl group. A selective beta blocker, it has been used in the emergency treatment of cardiac arrhythmias.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prenalterol pretreatment did not induce any marked changes, either in the stimulatory potency or affinity of the agonists in the two tissues or in the maximal response (ISA) of prenalterol in the papillary muscle." | 1.27 | Effects of in vivo treatment with isoprenaline or prenalterol on beta-adrenoceptor mechanisms in the heart and soleus muscle of the cat. ( Carlsson, E; Hedberg, A; Mattsson, H; Nerme, V, 1984) |
| "When dose-response curves are replicated, averaging the responses to each dose of drug reduces the slope of the mean curve." | 1.27 | A method for presenting and comparing dose-response curves. ( Carpenter, JR, 1986) |
| "Prazosin was 300 times more active than rauwolscine in inhibiting NA-induced contractions." | 1.27 | Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery. ( Andersson, KE; Hedlund, H, 1985) |
| "3 Propranolol caused a parallel shift to the right of the noradrenaline dose-response curve which was not changed by phentolamine." | 1.26 | alpha And beta-adrenoceptors in the detrusor muscle and bladder base of the pig and beta-adrenoceptors in the detrusor muscle of man. ( Larsen, JJ, 1979) |
| " Log dose-response curves to isoprenaline from spontaneously contracting muscle strips from rabbit uterus have been obtained." | 1.25 | Action of beta-adrenoceptor antagonists on the response to isoprenaline in the oestrogen dominated rabbit uterus. ( Nesheim, BI, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (97.14) | 18.7374 |
| 1990's | 1 (2.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lalloz, L | 1 |
| Loppinet, V | 1 |
| Coudert, G | 1 |
| Guillaumet, G | 1 |
| Loubinoux, B | 1 |
| Labrid, C | 1 |
| Beaughard, M | 1 |
| Dureng, G | 1 |
| Lamar, JC | 1 |
| Kenakin, TP | 1 |
| Beek, D | 1 |
| Johansson, U | 2 |
| Waldeck, B | 3 |
| Alkondon, M | 1 |
| Sivam, SP | 1 |
| Bhatia, S | 1 |
| Sen, P | 1 |
| Apperley, GH | 1 |
| Drew, GM | 1 |
| Sullivan, AT | 1 |
| Taylor, SE | 1 |
| Mattsson, H | 2 |
| Hedberg, A | 2 |
| Carlsson, E | 2 |
| Kimura, I | 1 |
| Katoh, H | 1 |
| Kimura, M | 1 |
| Nerme, V | 1 |
| Zaagsma, J | 2 |
| van der Heijden, PJ | 1 |
| van der Schaar, MW | 1 |
| Bank, CM | 1 |
| Maccarrone, C | 1 |
| Malta, E | 1 |
| Raper, C | 1 |
| Nergårdh, A | 1 |
| Boréus, LO | 1 |
| Naglo, AS | 1 |
| Cohen, ML | 1 |
| Wiley, KS | 1 |
| Meems, L | 1 |
| Boorsma, M | 1 |
| Bauer, V | 1 |
| Zakhari, S | 1 |
| Kelkar, VV | 2 |
| Gupta, RS | 1 |
| Jariwala, NU | 1 |
| Joshi, NJ | 1 |
| Hara, Y | 1 |
| Sato, E | 1 |
| Miyagishi, A | 1 |
| Aono, S | 1 |
| Nakatani, H | 1 |
| Larsen, JJ | 1 |
| Nesheim, BI | 1 |
| Jindal, MN | 1 |
| Shah, UH | 1 |
| Patel, VK | 1 |
| Reis, CC | 1 |
| Ek, B | 1 |
| Carpenter, JR | 1 |
| Yamada, S | 1 |
| Kashiwabara, T | 1 |
| Yamazawa, T | 1 |
| Harada, Y | 1 |
| Nakayama, K | 1 |
| Hedlund, H | 1 |
| Andersson, KE | 1 |
| Widmark, E | 1 |
| Levy, B | 1 |
| Anderson, GF | 1 |
| Kreulen, DL | 1 |
| Fredericks, CM | 1 |
| Lefkowitz, RJ | 1 |
| Weinstock, M | 1 |
| Schechter, Y | 1 |
| Erez, M | 1 |
| Shtacher, G | 1 |
| Horii, D | 1 |
| Kawada, T | 1 |
| Takeda, K | 1 |
| Imai, S | 1 |
| Harry, JD | 1 |
| Linden, RJ | 1 |
| Snow, HM | 1 |
| Olsson, OA | 1 |
| Persson, CG | 1 |
| Limbourg, P | 1 |
| Just, H | 1 |
| Lang, KF | 1 |
35 other studies available for practolol and Muscle Contraction
| Article | Year |
|---|---|
2-Benzodioxinylaminoethanols: a new class of beta-adrenergic blocking and antihypertensive agents.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Dioxins; Dose-Response Relationship, | 1981 |
Is prenalterol (H133/80) really a selective beta 1 adrenoceptor agonist? Tissue selectivity resulting from differences in stimulus-response relationships.
Topics: Adrenergic beta-Agonists; Airway Resistance; Animals; Cats; Guinea Pigs; In Vitro Techniques; Isopro | 1980 |
On the stereospecificity of the beta2-adrenoceptor blocking properties of prenalterol.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Guinea Pigs; In Vitro Techniques; Ma | 1980 |
Anticholinesterase effect of sotalol.
Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Carbachol; Cholinesterase In | 1981 |
beta 1-Adrenoceptors mediating relaxation of the guinea-pig trachea: experiments with prenalterol, a beta 1-selective adrenoceptor agonist.
Topics: Adrenergic beta-Agonists; Animals; Estradiol; Guinea Pigs; In Vitro Techniques; Male; Muscle Contrac | 1981 |
Prenalterol is an agonist at beta 2- as well as at beta 1-adrenoceptors.
Topics: Adrenergic beta-Agonists; Animals; Atenolol; Cats; Female; Isoproterenol; Lung; Male; Muscle Contrac | 1982 |
Pharmacological isolation of a single beta-adrenoceptor subtype makes Schild plots which have slopes of 1 possible for selective beta-adrenoceptor antagonists in carbachol-contracted guinea-pig trachea.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Carbachol; Guinea Pigs; In Vitro Techniques; Kinet | 1982 |
Intrinsic sympathomimetic activity of the partial agonist prenalterol in relation to beta adrenoceptor interaction in various tissues, in vitro.
Topics: Adrenergic beta-Agonists; Animals; Cats; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isopr | 1983 |
Difference between adrenergic beta 1- and beta 2-blocking effects on isoproterenol-induced Ca spike suppression in guinea-pig taenia coli.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Calcium; Dose-Response Relationship, Drug; Guinea | 1983 |
Effects of in vivo treatment with isoprenaline or prenalterol on beta-adrenoceptor mechanisms in the heart and soleus muscle of the cat.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cats; Female; Heart; Isoproterenol; Male; Musc | 1984 |
Differentiation of functional adrenoceptors in human and guinea pig airways.
Topics: Anaphylaxis; Animals; Bronchi; Corticosterone; Guinea Pigs; Histamine Release; Humans; Immunization; | 1984 |
Effects of prenalterol and its N-homoveratryl derivative in the anaesthetized cat.
Topics: Anesthesia; Animals; Blood Pressure; Cardiac Output; Cats; Female; Heart Rate; Hemodynamics; Isoprot | 1983 |
Characterization of the adrenergic beta-receptor in the urinary bladder of man and cat.
Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Butoxamine; Cats; Child; Child, Prescho | 1977 |
Specific enhancement of norepinephrine-induced contraction in rat veins after beta adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Animals; Drug Interactions; Electric Stimulation; In Vitro Techniques; | 1977 |
Beta-Adrenoceptor studies. 4. Influence of albumin on in vitro beta-adrenoceptor blocking and antiarrhythmic properties of propranolol, pindolol, practolol and metoprolol.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart | 1977 |
Pharmacological studies with beta-adrenoreceptor blocking agents I. Effect on the smooth muscle of the taenia coli of the guinea pig.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Colon; Guinea Pigs; In Vitro Techniques; Is | 1977 |
Antagonism by some beta-adrenoceptor-blocking agents to cholinergic stimulation of skeletal muscle in vitro.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Anura; Ethanolamines; Guinea Pigs; Mesylates; M | 1979 |
[Pharmacological properties of dl-2-(3'-t-butylamino-2'-hydroxypropylthio)-4-(5'-carbamoyl-2'-thienyl) thiazole hydrochloride (S-596), a new beta-adrenergic blocking agent (author's transl)].
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardi | 1979 |
alpha And beta-adrenoceptors in the detrusor muscle and bladder base of the pig and beta-adrenoceptors in the detrusor muscle of man.
Topics: Adult; Aged; Albuterol; Animals; Butoxamine; Carbachol; Female; Humans; In Vitro Techniques; Male; M | 1979 |
Action of beta-adrenoceptor antagonists on the response to isoprenaline in the oestrogen dominated rabbit uterus.
Topics: Adrenergic beta-Antagonists; Animals; Drug Interactions; Estrogens; Female; In Vitro Techniques; Iso | 1975 |
A study of some beta-adrenoceptor blocking agents on skeletal muscle.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anura; Cats; Diaphragm; Ele | 1975 |
Study of the contraction induced by norepinephrine and clonidine in the isolated guinea-pig ileum.
Topics: Animals; Atropine; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Co | 1991 |
Studies on mechanisms for beta-adrenoceptor mediated inhibition of colon motility.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colon; Gastrointestinal Motility; Hy | 1985 |
A method for presenting and comparing dose-response curves.
Topics: Adrenergic beta-Antagonists; Animals; Biometry; Dose-Response Relationship, Drug; Epinephrine; Guine | 1986 |
Demonstration of beta 1-adrenoceptor mediating relaxation of porcine coronary artery by radioligand binding and pharmacological methods.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-Antagonists; Ani | 1988 |
Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery.
Topics: Acetylcholine; Aged; Carbachol; Clonidine; Electric Stimulation; Ethanolamines; Humans; In Vitro Tec | 1985 |
Comparison of the effects of forskolin and isoprenaline on tracheal, cardiac and skeletal muscles from guinea-pig.
Topics: Animals; Cardiotonic Agents; Colforsin; Diterpenes; Guinea Pigs; Heart; In Vitro Techniques; Isoprot | 1985 |
Practolol blockade of cardiac but not vascular or uterine beta-adrenergic receptors in the anesthetized cat.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Blood Vessels; Cats; Depression, Chemical; Dos | 1973 |
Selective beta blockade of isolated rabbit detrusor muscle with practolol (AY21,011) and N-isopropylmethoxamine.
Topics: Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techni | 1973 |
Editorial: Selectivity in beta-adrenergic responses: clinical implications.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Bronchi; Butoxamin | 1974 |
Changes in beta-adrenoceptor-blocking activity produced by chemical modifications in the practolol molecule.
Topics: Adrenergic beta-Antagonists; Animals; Benzamides; Blood Pressure; Cats; Chemical Phenomena; Chemistr | 1974 |
Comparison of beta-adrenergic blocking activities of propranolol, isopropylmethoxamine, sotalol, practolol, alprenolol, pindolol, oxprenolol and D-32 in the atria and trachea of the guinea-pig.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Butylamines; Dose-Response Relationship, Drug; Ele | 1974 |
The effects of three beta-adrenoceptor blocking drugs on isolated preparations of skeletal and cardiac muscle.
Topics: Adrenergic beta-Antagonists; Animals; Depression, Chemical; Diaphragm; Electric Stimulation; Heart; | 1974 |
Potency ratio between the beta-adrenoceptor stimulants isoprenaline and terbutaline on rabbit detrusor muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; In Vitro Techniques; Isoproterenol; | 1974 |
[Comparative studies on practolol, pindolol and propranolol effect on hemodynamics and contractility of left ventricle in coronary disease patients].
Topics: Coronary Disease; Heart; Heart Ventricles; Hemodynamics; Humans; Muscle Contraction; Pindolol; Pract | 1973 |