practolol and Acute Liver Injury, Drug-Induced studies

practolol and Acute Liver Injury, Drug-Induced

Practolol: A beta-1 adrenergic antagonist that has been used in the emergency treatment of CARDIAC ARRYTHMIAS.
practolol : N-(4-Hydroxyphenyl)acetamide in which the hydrogen of the phenolic hydroxy group is substituted by a 3-(isopropylaminoamino)-2-hydroxypropyl group. A selective beta blocker, it has been used in the emergency treatment of cardiac arrhythmias.

Research Excerpts

Excerpt	Relevance	Reference
"Reserpine was uneffective in terms of liver derangement, but exerted some protection against the general toxic effect of A."	1.25	Effects of sympatholytic agents on amanita phalloides toxicity in the rat. ( Baccino, FM; Pernigotti, L; Torrielli, MV; Zuretti, MF, 1975)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (50.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (50.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

2 (50.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

2 (50.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Dawson, S	1
Stahl, S	2
Paul, N	1
Barber, J	1
Kenna, JG	2
Warner, DJ	1
Chen, H	1
Cantin, LD	1
Walker, CL	1
Noeske, T	1
Zuretti, MF	1
Pernigotti, L	1
Torrielli, MV	1
Baccino, FM	1
Rosner, I	1
Romero-Ferret, C	1
Mottot, G	1

Studies

Dawson, S

Stahl, S

Paul, N

Barber, J

Kenna, JG

Warner, DJ

Chen, H

Cantin, LD

Walker, CL

Noeske, T

Zuretti, MF

Pernigotti, L

Torrielli, MV

Baccino, FM

Rosner, I

Romero-Ferret, C

Mottot, G

Other Studies

4 other studies available for practolol and Acute Liver Injury, Drug-Induced

Article	Year
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters	2012
Effects of sympatholytic agents on amanita phalloides toxicity in the rat. Research communications in chemical pathology and pharmacology, 1975, Volume: 10, Issue:3 Topics: Acid Phosphatase; Animals; Butoxamine; Catecholamines; Chemical and Drug Induced Liver Injury; Epine	1975
Letter: Treatment of acute paracetamol poisoning. Lancet (London, England), 1973, Dec-01, Volume: 2, Issue:7840 Topics: Acetaminophen; Alprenolol; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationsh	1973

Article

Year

In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.

Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012

Effects of sympatholytic agents on amanita phalloides toxicity in the rat.

Research communications in chemical pathology and pharmacology, 1975, Volume: 10, Issue:3

Topics: Acid Phosphatase; Animals; Butoxamine; Catecholamines; Chemical and Drug Induced Liver Injury; Epine

1975

Letter: Treatment of acute paracetamol poisoning.

Lancet (London, England), 1973, Dec-01, Volume: 2, Issue:7840

Topics: Acetaminophen; Alprenolol; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationsh

1973