pqq cofactor has been researched along with Parkinson Disease in 4 studies
PQQ Cofactor: A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES.
pyrroloquinoline quinone : A pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 2 (50.00) | 2.80 |
Authors | Studies |
---|---|
Li, S | 2 |
Raja, A | 1 |
Noroozifar, M | 2 |
Kerman, K | 2 |
Zhou, J | 1 |
Ng, CH | 1 |
Basil, AH | 1 |
Hang, L | 1 |
Tan, R | 1 |
Goh, KL | 1 |
O'Neill, S | 1 |
Zhang, X | 1 |
Yu, F | 1 |
Lim, KL | 1 |
Zhang, Q | 1 |
Chen, S | 1 |
Yu, S | 1 |
Qin, J | 1 |
Zhang, J | 1 |
Cheng, Q | 1 |
Ke, K | 1 |
Ding, F | 1 |
4 other studies available for pqq cofactor and Parkinson Disease
Article | Year |
---|---|
Understanding the Inhibitory and Antioxidant Effects of Pyrroloquinoline Quinone (PQQ) on Copper(II)-Induced α-Synuclein-119 Aggregation.
Topics: alpha-Synuclein; Antioxidants; Copper; Dopaminergic Neurons; Humans; Parkinson Disease; PQQ Cofactor | 2022 |
Electrochemical flow injection analysis of the interaction between pyrroloquinoline quinone (PQQ) and α-synuclein peptides related to Parkinson's disease.
Topics: alpha-Synuclein; Flow Injection Analysis; Humans; Parkinson Disease; Peptides; PQQ Cofactor | 2021 |
Genetic or pharmacological activation of the Drosophila PGC-1α ortholog spargel rescues the disease phenotypes of genetic models of Parkinson's disease.
Topics: AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Drosophila; Drosophila Proteins; Gen | 2017 |
Neuroprotective effects of pyrroloquinoline quinone against rotenone injury in primary cultured midbrain neurons and in a rat model of Parkinson's disease.
Topics: Animals; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Mesencephalon; | 2016 |