Page last updated: 2024-10-20

pqq cofactor and Parkinson Disease

pqq cofactor has been researched along with Parkinson Disease in 4 studies

PQQ Cofactor: A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES.
pyrroloquinoline quinone : A pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Li, S2
Raja, A1
Noroozifar, M2
Kerman, K2
Zhou, J1
Ng, CH1
Basil, AH1
Hang, L1
Tan, R1
Goh, KL1
O'Neill, S1
Zhang, X1
Yu, F1
Lim, KL1
Zhang, Q1
Chen, S1
Yu, S1
Qin, J1
Zhang, J1
Cheng, Q1
Ke, K1
Ding, F1

Other Studies

4 other studies available for pqq cofactor and Parkinson Disease

ArticleYear
Understanding the Inhibitory and Antioxidant Effects of Pyrroloquinoline Quinone (PQQ) on Copper(II)-Induced α-Synuclein-119 Aggregation.
    ACS chemical neuroscience, 2022, 04-20, Volume: 13, Issue:8

    Topics: alpha-Synuclein; Antioxidants; Copper; Dopaminergic Neurons; Humans; Parkinson Disease; PQQ Cofactor

2022
Electrochemical flow injection analysis of the interaction between pyrroloquinoline quinone (PQQ) and α-synuclein peptides related to Parkinson's disease.
    The Analyst, 2021, Jul-21, Volume: 146, Issue:14

    Topics: alpha-Synuclein; Flow Injection Analysis; Humans; Parkinson Disease; Peptides; PQQ Cofactor

2021
Genetic or pharmacological activation of the Drosophila PGC-1α ortholog spargel rescues the disease phenotypes of genetic models of Parkinson's disease.
    Neurobiology of aging, 2017, Volume: 55

    Topics: AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Drosophila; Drosophila Proteins; Gen

2017
Neuroprotective effects of pyrroloquinoline quinone against rotenone injury in primary cultured midbrain neurons and in a rat model of Parkinson's disease.
    Neuropharmacology, 2016, Volume: 108

    Topics: Animals; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Mesencephalon;

2016