pqq cofactor has been researched along with Disease Models, Animal in 15 studies
PQQ Cofactor: A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES.
pyrroloquinoline quinone : A pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cognitive impairments were prevented and bioenergetic deficits partially reversed when Tg(+/-) rats were fed a nutritionally complete diet from weaning to 6-month-old supplemented with pyrroloquinoline quinone, a mitochondrial biogenesis stimulator with antioxidant and neuroprotective effects." | 1.46 | Synaptosomal bioenergetic defects are associated with cognitive impairment in a transgenic rat model of early Alzheimer's disease. ( Cassina, A; Castaño, EM; Cuello, AC; Do Carmo, S; Evelson, P; Galeano, P; Leal, MC; Magnani, N; Martino Adami, PV; Morelli, L; Quijano, C, 2017) |
| "Traumatic brain injury is one of the leading causes for adult disability and death." | 1.46 | The Effect of Pyrroloquinoline Quinone on Apoptosis and Autophagy in Traumatic Brain Injury. ( Qian, Y; Yan, M; Ye, Y; Yin, B; Zhang, L; Zhang, P; Zhao, J; Zhu, S, 2017) |
| "However, it is unclear whether intracerebral hemorrhage (ICH), as an acute devastating disease, can also benefit from PQQ in experimental conditions." | 1.42 | Protective Effect of Pyrroloquinoline Quinone (PQQ) in Rat Model of Intracerebral Hemorrhage. ( Cai, R; Dai, A; Ge, J; Jiang, Z; Lu, H; Shen, J; Song, X, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 4 (26.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 1 |
| Li, M | 1 |
| Chen, P | 1 |
| Shi, X | 1 |
| Min, Z | 1 |
| Zhou, J | 1 |
| Mao, R | 1 |
| Cui, B | 1 |
| Cheng, Y | 1 |
| Chen, Z | 1 |
| Devasani, K | 1 |
| Kaul, R | 1 |
| Majumdar, A | 1 |
| Ng, CH | 1 |
| Basil, AH | 1 |
| Hang, L | 1 |
| Tan, R | 1 |
| Goh, KL | 1 |
| O'Neill, S | 1 |
| Zhang, X | 1 |
| Yu, F | 1 |
| Lim, KL | 1 |
| Wen, H | 1 |
| He, Y | 1 |
| Zhang, K | 1 |
| Yang, X | 1 |
| Hao, D | 1 |
| Jiang, Y | 1 |
| He, B | 1 |
| Geng, Q | 1 |
| Gao, H | 1 |
| Yang, R | 1 |
| Guo, K | 1 |
| Miao, D | 1 |
| Lu, H | 1 |
| Shen, J | 1 |
| Song, X | 1 |
| Ge, J | 1 |
| Cai, R | 1 |
| Dai, A | 1 |
| Jiang, Z | 1 |
| Jia, D | 1 |
| Duan, F | 1 |
| Peng, P | 1 |
| Sun, L | 1 |
| Ruan, Y | 1 |
| Gu, J | 1 |
| Martino Adami, PV | 1 |
| Quijano, C | 1 |
| Magnani, N | 1 |
| Galeano, P | 1 |
| Evelson, P | 1 |
| Cassina, A | 1 |
| Do Carmo, S | 1 |
| Leal, MC | 1 |
| Castaño, EM | 1 |
| Cuello, AC | 1 |
| Morelli, L | 1 |
| Zhang, P | 1 |
| Ye, Y | 1 |
| Qian, Y | 1 |
| Yin, B | 1 |
| Zhao, J | 1 |
| Zhu, S | 1 |
| Zhang, L | 1 |
| Yan, M | 1 |
| Bauerly, K | 1 |
| Harris, C | 1 |
| Chowanadisai, W | 1 |
| Graham, J | 1 |
| Havel, PJ | 1 |
| Tchaparian, E | 1 |
| Satre, M | 1 |
| Karliner, JS | 2 |
| Rucker, RB | 1 |
| Gong, D | 1 |
| Geng, C | 1 |
| Jiang, L | 1 |
| Aoki, Y | 1 |
| Nakano, M | 1 |
| Zhong, L | 1 |
| Zhu, BQ | 1 |
| Zhou, HZ | 1 |
| Teerlink, JR | 1 |
| Liu, S | 1 |
| Li, H | 1 |
| Ou Yang, J | 1 |
| Peng, H | 1 |
| Wu, K | 1 |
| Liu, Y | 1 |
| Yang, J | 1 |
| Zhang, Y | 1 |
| Feustel, PJ | 1 |
| Kimelberg, HK | 1 |
1 review available for pqq cofactor and Disease Models, Animal
| Article | Year |
|---|---|
Mini-review: Functions and Action Mechanisms of PQQ in Osteoporosis and Neuro Injury.
Topics: Animals; Antioxidants; Disease Models, Animal; Gram-Positive Bacteria; Gram-Positive Bacterial Infec | 2020 |
14 other studies available for pqq cofactor and Disease Models, Animal
| Article | Year |
|---|---|
Anti-inflammatory and Antioxidant Effects of Pyrroloquinoline Quinone in L-NAME-Induced Preeclampsia-Like Rat Model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Pressure; Disease Models, Animal; Female; Inj | 2022 |
Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Inflammation; Janu | 2022 |
Supplementation of pyrroloquinoline quinone with atorvastatin augments mitochondrial biogenesis and attenuates low grade inflammation in obese rats.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Blood Glucose; Cytokines; Disease Models, Animal; D | 2020 |
Genetic or pharmacological activation of the Drosophila PGC-1α ortholog spargel rescues the disease phenotypes of genetic models of Parkinson's disease.
Topics: AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Drosophila; Drosophila Proteins; Gen | 2017 |
Pyrroloquinoline Quinone Prevents Estrogen Deficiency-Induced Osteoporosis by Inhibiting Oxidative Stress and Osteocyte Senescence.
Topics: Animals; Cellular Senescence; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Estrogens; | 2019 |
Protective Effect of Pyrroloquinoline Quinone (PQQ) in Rat Model of Intracerebral Hemorrhage.
Topics: Animals; Cerebral Hemorrhage; Disease Models, Animal; Male; Neuroprotective Agents; Oxidative Stress | 2015 |
Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice.
Topics: Animals; Antioxidants; Cell Death; Cell Movement; Cell Proliferation; Cells, Cultured; Cytokines; Di | 2015 |
Synaptosomal bioenergetic defects are associated with cognitive impairment in a transgenic rat model of early Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Diet Therapy; Disease Models, Animal; Electron Tr | 2017 |
The Effect of Pyrroloquinoline Quinone on Apoptosis and Autophagy in Traumatic Brain Injury.
Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Autophagosomes; Autophagy; Brain Injuries, Traumat | 2017 |
Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats.
Topics: Animals; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Metabolism; Glucose; | 2011 |
Effect of pyrroloquinoline quinone on neuropathic pain following chronic constriction injury of the sciatic nerve in rats.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; | 2012 |
Pyrroloquinoline quinone (PQQ) decreases myocardial infarct size and improves cardiac function in rat models of ischemia and ischemia/reperfusion.
Topics: Animals; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Function Tests | 2004 |
Enhanced rat sciatic nerve regeneration through silicon tubes filled with pyrroloquinoline quinone.
Topics: Animals; Disease Models, Animal; Male; Nerve Regeneration; Neural Conduction; PQQ Cofactor; Prosthes | 2005 |
Neuroprotection by pyrroloquinoline quinone (PQQ) in reversible middle cerebral artery occlusion in the adult rat.
Topics: Animals; Behavior, Animal; Brain; Brain Infarction; Cytoprotection; Disease Models, Animal; Dose-Res | 2006 |