ppm 18 has been researched along with Leukemia, Myeloid, Acute in 1 studies
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In addition, we demonstrated that treatment of human acute myeloid leukemia cell line MV4-11 with the selective HDAC6 inhibitors decreases levels of mutant FLT-3 and constitutively active STAT5 and attenuates Erk phosphorylation, all of which are associated with the inhibitor's selective toxicity against leukemia." | 1.38 | A novel class of small molecule inhibitors of HDAC6. ( Chou, CJ; Inks, ES; Jesinkey, SR; Josey, BJ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inks, ES | 1 |
| Josey, BJ | 1 |
| Jesinkey, SR | 1 |
| Chou, CJ | 1 |
1 other study available for ppm 18 and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
A novel class of small molecule inhibitors of HDAC6.
Topics: Antineoplastic Agents; Cell Line, Tumor; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Hist | 2012 |