Page last updated: 2024-11-03

ppm 18 and Leukemia, Myeloid, Acute

ppm 18 has been researched along with Leukemia, Myeloid, Acute in 1 studies

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research Excerpts

ExcerptRelevanceReference
"In addition, we demonstrated that treatment of human acute myeloid leukemia cell line MV4-11 with the selective HDAC6 inhibitors decreases levels of mutant FLT-3 and constitutively active STAT5 and attenuates Erk phosphorylation, all of which are associated with the inhibitor's selective toxicity against leukemia."1.38A novel class of small molecule inhibitors of HDAC6. ( Chou, CJ; Inks, ES; Jesinkey, SR; Josey, BJ, 2012)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inks, ES1
Josey, BJ1
Jesinkey, SR1
Chou, CJ1

Other Studies

1 other study available for ppm 18 and Leukemia, Myeloid, Acute

ArticleYear
A novel class of small molecule inhibitors of HDAC6.
    ACS chemical biology, 2012, Feb-17, Volume: 7, Issue:2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Hist

2012