pp242 and Neoplasms

pp242 has been researched along with Neoplasms* in 1 studies

Reviews

1 review(s) available for pp242 and Neoplasms

Article	Year
Allosteric and ATP-competitive kinase inhibitors of mTOR for cancer treatment. Bioorganic & medicinal chemistry letters, 2010, Aug-01, Volume: 20, Issue:15 Over the past few years a number of components of the PI3K/mTOR pathway have been the subject of intense drug discovery activities both in pharmaceutical companies and in academia. This review article summarizes progress made in the identification and development of allosteric and ATP-competitive kinase inhibitors of mTOR and their potential therapeutic use in oncology. Topics: Adenosine Triphosphate; Allosteric Regulation; Antineoplastic Agents; Humans; Neoplasms; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Pyrimidines; Signal Transduction; TOR Serine-Threonine Kinases	2010

Article

Year

Allosteric and ATP-competitive kinase inhibitors of mTOR for cancer treatment.

Bioorganic & medicinal chemistry letters, 2010, Aug-01, Volume: 20, Issue:15

Over the past few years a number of components of the PI3K/mTOR pathway have been the subject of intense drug discovery activities both in pharmaceutical companies and in academia. This review article summarizes progress made in the identification and development of allosteric and ATP-competitive kinase inhibitors of mTOR and their potential therapeutic use in oncology.

Topics: Adenosine Triphosphate; Allosteric Regulation; Antineoplastic Agents; Humans; Neoplasms; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Pyrimidines; Signal Transduction; TOR Serine-Threonine Kinases

2010