povidone-iodine and Halitosis

The purpose of this study was to assess the effects of 4 types of widely used commercial mouth rinses on third molar surgery-related oral malodor.. In this double-blind selective clinical trial, 80 participants (40 women, 40 men) who had undergone third molar surgery were divided into 5 groups, and different mouth rinses were given to each: 0.2% chlorhexidine gluconate (Chx), 0.12% chlorhexidine gluconate with 0.15% benzydamine hydrochloride (Chx+Bzd), 7.5% polyvinylpyrrolidone iodine (Pvp), 0.15% benzydamine hydrochloride (Bzd), and sterile saline solution (Ss), with other routine medications. Oral malodor of patients was evaluated with 3 methods; using a Halimeter, an organoleptic method, and patient self-evaluation. Measurements were performed preoperatively and postoperatively (pre-op, third, eighth, and fifteenth days).. Bad breath parameters systematically increased (P < .05) in all groups after third molar surgery on the third and eighth days. The Pvp and Ss groups showed higher scores when volatile sulfur compounds were considered. When organoleptic and patient self-evaluation scores were considered, the Bzd and Ss groups had higher scores than the others on the third and eighth days. The difference between the pre-op day and the fifteenth day was not significant in all groups in terms of all measures.. Third molar surgery-related oral malodor increases during the first postoperative week and decreases to the preoperative level after 15 days. Results from the 3 different methods showed that Chx and Chx+Bzd mouth rinses are more effective mouth rinses than the others on third molar surgery-related oral malodor.

Topics: Adolescent; Adult; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Benzydamine; Breath Tests; Chlorhexidine; Double-Blind Method; Drug Combinations; Female; Halitosis; Humans; Male; Molar, Third; Mouthwashes; Povidone-Iodine; Self-Assessment; Sodium Chloride; Sulfur Compounds; Tooth Extraction; Tooth, Impacted

Volatile sulphur compounds (VSC), hydrogen sulphide, methyl mercaptan and dimethyl sulphide are by-products derived in oral cavity through putrefactive activity of microorganisms. VSC are the principal cause of physiological oral malodour. There are indications that these compounds are cytotoxic to oral tissues. Hence, it has been considered that the prevention of oral malodour has an important role in preventive dentistry. The objective of this study is to ascertain the effect of two mouthwashes, sodium azulenesulphonic acid and povidone-iodine, which are frequently used in dental clinics, on concentration of VSC in mouth air. The VSC were analyzed using VSC analysis system. VSC were determined at immediately after rince and at one, two and three hours after rince. The results indicated that neither mouthwash was very effective in controlling VSC production. No reduction in VSC was observed at one and two hour post-rinsing with sodium azulenesulphonic acid mouthwash, and only 39% reduction of total sulphur of VSC was observed at one hour following the use of the povidone-iodine containing products. However, this effect was lost within two hours post-rinsing.

Topics: Azulenes; Halitosis; Humans; Mouthwashes; Povidone; Povidone-Iodine; Sesquiterpenes