povidone-iodine and HIV-Infections

Topics: Administration, Oral; Animals; Anti-HIV Agents; Blood; Cats; Equipment Contamination; General Surgery; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Instillation, Drug; Lymph; Models, Animal; Needlestick Injuries; Povidone-Iodine; Time Factors; Tourniquets

Topics: Anti-HIV Agents; Anti-Infective Agents, Local; HIV Infections; Humans; Ophthalmic Solutions; Povidone-Iodine; Risk Factors

This article describes the clinical features and management of noma (cancrum oris) in HIV/AIDS patients.. Eight HIV/AIDS patients were studied. Clinical presentation was different in all of the cases. Conservative debridement under local anesthesia with an antibiotic was performed.. Satisfactory resolution of the acute phase of this dangerous infection was achieved.. Minimal but thorough debridement of necrotic tissue along with lavage with povidone-iodine is effective in controlling this infective process. However, long-term sequelae of noma are not possible because of the underlying HIV infection from which the patients inevitably soon succumbs.

Topics: Adult; Child, Preschool; Debridement; Female; HIV Infections; Humans; Infant; Male; Noma; Povidone-Iodine; Therapeutic Irrigation

The results of Betadine treatment obtained in the course of a one-year period proved the usefulness of the bacteriostatic and bactericidal product as a disinfectant of the skin and mucosa in immuno-deficiency diseases, in our cases in AIDS (but supposedly in other similar diseases as well). In these diseases this new therapeutic means does supply a need. The solution was successfully used in patients in whom superficial decontamination is of high importance and whose cutaneous and mucosal infections had raised therapeutic problems for years. Side-effects were not observed. The product could be easily applied. If the germ count of the atrophying pathogen is not very high and the lesion is due supposedly to mixed infection, the product will be effective even in monotherapy. Similarly, in mild mycotic infections systemic therapy could be avoided. In cases of purulent alterations the solution is successfully applied as an adjuvant to antibacterial treatment and its continuous use prevents early recurrence. The long-term use of the product did not cause side-effects, irritation of the skin or the mucosa.

Topics: Anti-Bacterial Agents; Baths; Drug Evaluation; Drug Therapy, Combination; HIV Infections; Humans; Mouth Diseases; Oral Hygiene; Povidone-Iodine; Skin Diseases, Infectious; Solutions