povidone-iodine and Enterobacteriaceae-Infections

Four cases of infected vascular prosthetic graft in the groin successfully treated with povidone-iodine solution using a conservative approach are described here. In all patients the same technique was used. After complete debridement, the prosthetic graft in the groin was completely exposed. The wound was cleansed with hydrogen peroxide and then dressed with gauze soaked in 1:10 sterile water-diluted povidone-iodine solution. The dressings were changed twice a day. The patients were supplemented by systemic therapy of an appropriate antibiotic. All patients were observed in the intensive care unit. In all patients this treatment method led to control of infection and healing of the wound. Thus, it was not necessary to remove the prosthetic graft and patients were spared a major surgical intervention. At follow-up, the prosthetic grafts remain patent without any signs of recurrence of infection.

Topics: Aged; Anti-Infective Agents, Local; Arterial Occlusive Diseases; Blood Vessel Prosthesis; Enterobacteriaceae Infections; Female; Femoral Artery; Groin; Humans; Iliac Artery; Lower Extremity; Male; Middle Aged; Popliteal Artery; Povidone-Iodine; Prosthesis-Related Infections; Streptococcal Infections

The incidence of catheter-associated urinary tract infections (UTIs) becomes higher with prolongation of the indwelling period of a catheter. As to the entry of bacteria, ascending UTIs have now attracted attention. In the present study. the metal area was examined bacteriologically and the possibility to use antiseptics for blocking the route of developing infections was investigated. The subjects included 72 patients with an indwelling, urethral catheter inserted post-operatively. These patients were divided into three groups treated with once or twice daily application of povidone-iodine or once daily application of povidone-iodine cream. In these groups, the relation between changes in isolation of bacteria from the meatal area and the incidence of UTI was evaluated. It was found that reduction in bacterial count by antisepsis is effective to prevent ascending UTIs. Moreover, once daily application of povidone-iodine was proven to be effective in male patients. The effective antisepsis in females was twice daily application of povidone-iodine.

Topics: Anti-Infective Agents, Local; Antisepsis; Bacteria; Bacteriuria; Burkholderia; Catheters, Indwelling; Chemoprevention; Colony Count, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Enterococcus; Female; Gram-Positive Bacterial Infections; Humans; Incidence; Iodophors; Male; Postoperative Care; Povidone-Iodine; Sex Factors; Staphylococcal Infections; Staphylococcus; Urethra; Urinary Catheterization; Urinary Tract Infections

Antibacterial activity of surgical adhesive films containing various antiseptics in the adhesive layer was studied experimentally. It was shown that the adhesive films containing 0.1 to 1% (in terms of active iodine) of iodopyrone had a stable bactericidal action and were effective against to the main causative agents of surgical infections, i. e. Staphylococcus spp., E. coli, Klebsiella spp., Pseudomonas aeruginosa and others.

Topics: Anti-Infective Agents, Local; Antisepsis; Drug Combinations; Drug Evaluation, Preclinical; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Occlusive Dressings; Potassium Iodide; Povidone-Iodine; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Staphylococcus aureus; Surgical Wound Infection; Tissue Adhesives

Topics: Aged; Bacterial Infections; Cardiac Surgical Procedures; Child, Preschool; Enterobacter; Enterobacteriaceae Infections; Escherichia coli Infections; Female; Humans; Infant; Klebsiella Infections; Male; Mediastinal Diseases; Middle Aged; Povidone; Povidone-Iodine; Proteus Infections; Pseudomonas Infections; Serratia; Staphylococcal Infections; Sternum; Streptococcal Infections; Surgical Wound Infection; Therapeutic Irrigation

Topics: Antisepsis; Cross Infection; Drug Combinations; Enterobacteriaceae Infections; Evaluation Studies as Topic; Humans; Iodine; Povidone; Povidone-Iodine; Surgical Procedures, Operative; Surgical Wound Infection