povidone-iodine and Diabetic-Neuropathies

The definition for the diabetic foot is infection, ulceration or destruction of deep tissues of the foot associated with neuropathy or peripheral vascular disease in the lower extremity of people with diabetes. Non-diabetic patients may suffer the same risks when neuropathy and arteriopathy are present. Knowing that 85% of amputations are preceded by foot ulcers, prevention is primordial. At the onset of an ulcer, immediate treatment must be undertaken and preferably by an interdisciplinary team. Delayed healing and increased risk of infection are often due to an associated vascular disease. While the array of dressings is expansive there is no «gold standard» treatment or «miracle dressing» described for foot ulcers. The management consists of wound analysis, debridement, woundcare and especially offloading.

Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Bandages; Combined Modality Therapy; Debridement; Diabetic Angiopathies; Diabetic Foot; Diabetic Neuropathies; Humans; Necrosis; Povidone-Iodine; Wound Infection

Examined 22 patients with diabetes mellitus (DM) type II of neuropathic form of diabetic foot syndrome (DFS). In 12 patients (comparison group) local povidone-iodine was used main in 10 (study group), except povidone-iodine, in the phase of exudation used tyrothricin in gel form, the granulation and epithelization phase, after cleaning the wounds, were injected intradermally 1 ml of injecting material for skin regeneration Lacerta. Trophic defects in 9 (90%) patients of the main group during the observation period healed completely, in the comparison group complete healing of the ulcer reached in 2 (16.7%) patients, the rest-wounds, although purified, however, were lethargic granulation, epithelization occurred very slowly. Consequently, the use of the proposed method allows to achieve more rapid healing of trophic ulcers that do not heal continued in patients of neuropathic forms of DFS.

Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Biological Factors; Diabetes Mellitus, Type 2; Diabetic Foot; Diabetic Neuropathies; Female; Humans; Male; Middle Aged; Povidone-Iodine; Protamines; Re-Epithelialization; Skin; Treatment Outcome; Tyrothricin